Medicine and Health Sciences Commons^™

The Shape School: Assessing Executive Function In Preschool Children, K. A. Espy

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

Age-related changes in executive function were examined on a new task, the Shape School, in 70 preschool children (32-68 months old). The Shape School is a colorful storybook designed to examine inhibition and switching processes in young children. Results confirmed that task efficiency varied significantly with age, with older age groups outperforming younger groups. Furthermore, inhibition efficiency improved significantly between 3 to 4 years of age, whereas switching skills showed developmental improvement from 4 to 5 years of age. These results suggest that the Shape School is sensitive to maturational effects and that performance can be parsed into inhibition and …

Ms211: By Healthcare Committee Doc, Armin Weinberg

Works on Radiation Effects: 1990-2020

Selected material about the healthcare system/status in Russia circa 1997. It looks like a series of pieces from a healthcare publication. Clearly this was a part of our trying to assess the opportunity to further our work with Dennis Sokol of the American Medical Centers that Ambassador Strauss connected us with as well as the post-Chernobyl opportunities for our colleagues in the Former USSR. See more at Armin Weinberg, PhD Papers and its finding aid.

Triazine Herbicide Exposure And Breast Cancer Incidence: An Ecologic Study Of Kentucky Counties, Michele A. Kettles, Steven R. Browning, Timothy Scott Prince, Sanford W. Horstman

Preventive Medicine and Environmental Health Faculty Publications

The incidence of breast cancer in the United States has steadily increased for the past three decades. Exposure to excess estrogen, in both natural and synthetic forms, has been implicated as a risk factor for the development of this disease. Considerable interest has been focused on organochlorines, such as the triazine herbicides, and their possible role in the initiation or promotion of human breast cancer. To explore this relationship, an ecologic study of Kentucky counties was designed. Exposure to triazines was estimated by use of water contamination data, corn crop production, and pesticide use data. A summary index of triazine …

Fetal Abdominal Circumference In Normal Pregnancy:Chulalongkorn Hospital Population, Boonehai Uerpairojkit, Saknan Manotaya, Somehai Tanawattanaeharoen, Yuen Tannirandom, Wanieha Settanarak, Dhiraphongs Charoenvidhya

Chulalongkorn Medical Journal

No abstract provided.

The Association Of Hla-Drb Genes And The Shared Epitope With Rheumatoid Arthritis In Pakistan, K Hameed, S Bowman, E Kondeatis, R Vaughan, T Gibson

Section of Internal Medicine

The association of particular HLA-DR alleles and the shared epitope with rheumatoid arthritis (RA) is now well established. The strength of these links varies between races. Furthermore, the proposition that the presence of the shared epitope is indicative of severe disease has been more difficult to sustain in non-Europeans. This study examines the frequency of HLA-DR and HLA-DRB1 amongst Pakistanis for the first time. Using the polymerase chain reaction (PCR) and sequence-specific oligonucleotide probes (PCR-SSOP) and primers (PCR-SSP), HLA-DR phenotype and genotype frequencies were ascertained in 86 RA hospital out-patients and 79 healthy controls matched for age, gender and ethnicity. …

Expression Of Protein Kinase C Beta In The Heart Causes Hypertrophy In Adult Mice And Sudden Death In Neonates, Joel C. Bowman, Susan F. Steinberg, Tiangrong Jiang, David L. Geenen, Glenn I. Fishman, Peter M. Buttrick

Peer Reviewed Articles

Protein kinase C (PKC) activation in the heart has been linked to a hypertrophic phenotype and to processes that influence contractile function. To establish whether PKC activation is sufficient to induce an abnormal phenotype, PKCbeta was conditionally expressed in cardiomyocytes of transgenic mice. Transgene expression in adults caused mild and progressive ventricular hypertrophy associated with impaired diastolic relaxation, whereas expression in newborns caused sudden death associated with marked abnormalities in the regulation of intracellular calcium. Thus, the PKC signaling pathway in cardiocytes has different effects depending on the timing of expression and, in the adult, is sufficient to induce pathologic …

Occupational Therapy's Link To Vocational Reeducation, 1910-1925., Sharon A. Gutman

Department of Occupational Therapy Faculty Papers

The development of occupational therapy is rooted in early 20th century medical reform. During the early 1910s, several members of the medical profession, human service workers, and the larger American society were increasingly disturbed by medical practices that did not consider the individual's personal experience of disability. Occupational therapy was developed, in part, out of this desire to provide persons with treatment that helped them to function in their communities despite their disability. Early occupational therapy leaders envisioned the fledgling profession as a societal service capable of assisting persons with disabilities to return to both work and community life. Vocational …

Non-Visualization Of Lung Markings Below Hemidiaphragm In Subtle Subpulmonic Effusion: An Old Sign Resuscitated, Y A. Husen, T R. Khalid, Z A. Khan, M Y. Sheikh

Department of Radiology

To assess the lack of visibility of vascular markings under the hemidiaphragm on a frontal chest radiograph as a sign of pleural effusion, fifteen patients were collected showing this sign. Pleural effusion was diagnosed by ultrasound, comparison with previous or subsequent chest x-ray or computed tomography. Patients in the study group exhibited this sign in the absence of the classical signs of pleural effusion. In the control group, lack of visibility of blood vessels was observed in only 4.2% cases. Non-visualization of vascular markings below the hemidiaphragm should alert the interpreter to the possible presence of pleural effusion and a …

Modulation Of The Rat Potassium Channel Kv1.5, Daniel Benjamin Saal

Yale Medicine Thesis Digital Library

1. Kv1.5 is a delayed rectifier-type potassium channel. We have examined the localization of the channel protein using a polyclonal antibody against Kv1.5. This channel is expressed in numerous regions of the brain, primarily in glial cells. Its expression is particularly intense in the endfoot processes which abut the microvasculature of the brain. It is also expressed in the cell bodies and cellular processes in the pituitary.2. Immunoprecipitation of the Kv1.5 protein, from HEK 293 cells which were transformed with the Kv1.5 gene, revealed that the channel is phosphorylated and that treatment of cells with dibutyryl cyclic AMP (dibcAMP) or …

Predicting Red Blood Cell Transfusions In Very Low Birth Weight Infants Based On Clinical Risk Factors., David A. Paul, Stephen A. Pearlman, Kathleen H. Leef, John L. Stefano

Department of Pediatrics Faculty Papers

OBJECTIVE: To describe the clinical factors most predictive of red blood cell transfusion in very low birth weight (VLBW) infants.

STUDY DESIGN: Retrospective review of VLBW infants cared for at a single level III NICU during a two year period, n = 199.

RESULTS: Overall transfusion requirement was 4.6 +/- 6.2 transfusions/infant/hospital course. Length of hospital stay, days of mechanical ventilation, requirement for dopamine support, birth weight, initial hematocrit, periventricular leukomalacia and necrotizing enterocolitis all independently correlated with number of transfusions and donors. Bronchopulmonary dysplasia and patent ductus arteriosus were associated with donor but not transfusion number.

CONCLUSIONS: Our data …

Induction Of Labor By Vaginal Prostaglandin E2 (Pge2):A Randomized Study Comparing Gel With The Suppository, Somchai Tanawattanacharoen

Chulalongkorn Medical Journal

No abstract provided.

The Availability Of Inferences In Children And Young Adults, Gerilyn A. Katz

Student Work

Much of the research on age-related differences in the ability to inhibit irrelevant information in a given task has been on the study of younger and older adults. Only a minimal amount of research has focused on the developmental differences in children and young adults. Accordingly, the purpose of this paper is to examine whether age-related differences exist between children and young adults in processes consistent with inhibition.

Third-, sixth-grade children, and college undergraduates listened to twenty-four garden path passages containing either expected or unexpected, but acceptable, conclusions. The twenty-four passages were divided into four subsets, with each subset containing …

Open Fractures Caused By High Velocity Missiles: The Outcome Of Treatment Of 39 Fractures Followed For 1-3 Years, M A. Khan, R Hussain, S H. Khan, M Umar

Department of Surgery Docs

Between 1993 and 1995, thirty-three patients having 39 fractures caused by missiles fired from a high velocity rifle were reviewed retrospectively between 1 and 3 years after injury and the outcome of treatment assessed. Majority (33 out of 39) were Grade III. Union was achieved in 35 out of 39 fractures, there was deep infection and delayed union in one case each. Non-union occurred in three fractures. The fractures were stabilized using different techniques, but highest complication rate was seen with the use of the static external fixator. This was related to the severe nature of the injury as well …

หน่วยทารกแรกเกิด, Nimit Taechakraichana

Chulalongkorn Medical Journal

No abstract provided.

Ob&Gyn Department: The Great Stride Toward The Year 2000, N. Taechakraichana

Chulalongkorn Medical Journal

No abstract provided.

Assessment Of Abnormal Uterine Bleeding: Sonographic Role And The Changing Status, B. Uerpairojkit

Chulalongkorn Medical Journal

No abstract provided.

Dna Proliferation Indices In Papillary Immaturemetaplasia Of The Cervix, Prasert Trivijitsilp, Cp Crum

Chulalongkorn Medical Journal

No abstract provided.

Termination Of Second And Third Trimester Pregnancyby Misoprostol, Saknan Manotaya, Wiboon Kamolpomwijit

Chulalongkorn Medical Journal

No abstract provided.

Isolated Torsion Of The Fallopian Tube, Ruangsak Lertkhachonsuk, Wanwadee Sripitak

Chulalongkorn Medical Journal

No abstract provided.

Uterine Inversion: A Case Report, Sukanya Chaikittisilpa

Chulalongkorn Medical Journal

No abstract provided.

Calcium And Postmenopausal Osteoporosis, K. Panyakhamlerd, S. Chaikittisilpa, N. Taechakraichana, K. Limpaphayom

Chulalongkorn Medical Journal

No abstract provided.

An Evaluation Of The Sensitivity Of Subjects With Peanut Allergy To Very Low Doses Of Peanut Protein: A Randomized, Double-Blind, Placebo-Controlled Food Challenge Study, Jonathan O'B. Hourihane, Sally A. Kilburn, Julie A. Nordlee, Susan L. Hefle, Steve L. Taylor, John O. Warner

Department of Food Science and Technology: Faculty Publications

The minimum dose of food protein to which subjects with food allergy have reacted in double-blind, placebo-controlled food challenges is between 50 and 100 mg. However, subjects with peanut allergy often report severe reactions after minimal contact with peanuts, even through intact skin.

Objective: We sought to determine whether adults previously proven by challenge to be allergic to peanut react to very low doses of peanut protein.

Methods: We used a randomized, double-blind, placebo-controlled food challenge of 14 subjects allergic to peanuts with doses of peanut ranging from 10 μg to 50 mg, administered in the form of …

Managed Care Accreditation: Decoding The Acronyms, Randall K. Abbott, Joanne Gatti-Petito

Nursing Faculty Publications

While their health care plan's accreditation status is of increasing importance to employers, they are faced with a bewildering array of accreditation groups and standards. No accreditation organization can assure quality of care, but careful evaluation of accreditation standards, processes and results can help steer decision making in the right direction.

Élaboration D'Un Modèle De Prédiction Des Contraintes In Situ Dans Le Nord-Ouest Québécois, Robert Corthésy, Maria Helena Leite, Denis E. Gill

Rapports de recherche scientifique

No abstract provided.

Farmer Crushed When Run Over By Tractor And Disc, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Tractors/Logging

A 75-year-old farmer was killed when he was run over by a tractor and disc attachment. The farmer attempted to start the engine on a tractor while he stood on the ground beside it, a practice which was not unusual for him. The transmission had been left in gear and when the ignition was started the tractor lurched forward knocking the victim to the ground. The tractor continued to move forward, running over the victim. His wife went to search for him when she realized he had been gone from the house for quite some time. She found him in …

Role Of Egr-1 Gene Expression In B Cell Receptor-Induced Apoptosis In An Immature B Cell Lymphoma, Subramanian Muthukkumar, Seong-Su Han, Sumathi Muthukkumar, Vivek M. Rangnekar, Subbarao Bondada

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Ligation of B cell receptor (BCR) on BKS-2, an immature B cell lymphoma by anti-IgM antibodies (Ab) caused apoptosis. Here we report that signaling through B cell receptor in wild type BKS-2 cells down-regulated the expression of Egr-1, a zinc finger-containing transcription factor. A reduction in the level ofEgr-1 mRNA could be demonstrated as early as 30 min after the ligation of BCR on BKS-2 cells. Immunocytochemical and Western blot analysis revealed that the expression of EGR-1 protein was also inhibited by anti-IgM treatment. Antisense oligonucleotides to Egr-1 caused growth inhibition and apoptosis in BKS-2 cells, suggesting that …

The Ontological Argument For Colombian Narcoguerrillas In United States (Us) Anti-Drug Programs, Ibpp Editor

International Bulletin of Political Psychology

This article describes some conceptual fallacies in US anti-drug programs towards Colombia.

Cross-Validation Of The Injury Behavior Checklist In A School-Age Sample, Richard Potts, Isaac Martinez, Angela Dedmon, Leslie Schwarz, David Dilillo, Lisa Swisher

Department of Psychology: Faculty Publications

Examined descriptive characteristics, internal validity, and convergent validity of the Injury Behavior Checklist (IBC) in a sample of 7- to 10-year-old children. Although the IBC was originally designed for use with preschool children, results of the present study showed that it has acceptable psychometric qualities for use with children as old as 9 years. The IBC shows promise as an easily administered instrument for research on psychological and behavioral mechanisms of child hood injury, as well as for individual screening for injury liability.

Right Medial Temporal-Lobe Contribution To Object-Location Memory, B Milner, Ingrid Johnsrude, J Crane

Brain and Mind Institute Researchers' Publications

An important aspect of normal human memory, and one humans share with many other species, is the ability to remember the location of objects in their environment. There is by now strong evidence from the study of epileptic patients undergoing brain surgery that right temporal-lobe lesions that encroach extensively upon the hippocampal and parahippocampal gyrus impair the delayed, but not the immediate, recall of the location of objects within a random array. These findings have now been extended to a multiple-trial, spatial-array learning task; by including not only patients tested after unilateral anterior temporal lobectomy but also those with a …

What's Happening: October 29, 1997, Maine Medical Center

What's Happening

No abstract provided.