Medicine and Health Sciences Commons^™

A Pharmacologic Investigation Of The Antiinflammatory Activity Of Cryogenine, Donald Saadia Kosersky

University of the Pacific Theses and Dissertations

This study was conducted in an attempt to define the anti inflammatory efficacy of cryogenine, the major alkaloid of Heimia salicifolia Link and Otto. The anti inflammatory effects produced by cryogenine, phenylbutazone, indomethacin, mefenamic acid, paramethasone, hydrocortisone and 6-mercaptopurine were compared considering the sequential changes in various motameters during the course of adjuvant-induced polyarthritis in rats. Polyarthritis was induced by the subplantar injection of a suspension of heat-killed Mycobacterium butyricus in mineral oil into the right hind paw of Sprague-Dawley rats. The manifestations of the diseases were monitored in terms of hind paw swelling, subjective appearance of secondary lesions, impairment …

Antibradykinin Evaluation Of Cryogenine And Selected Other Agents, Ralph William Trottier Jr.

University of the Pacific Theses and Dissertations

One intent of this study was to detect and to define any antibradykinin capacity that cryogenine may have using both in vivo and in vitro pharmacological models. The activity of cryogenine in these tests was compared to a variety of clinically-proven anti-inflammatory compounds as well as to other agents known to possess anti-inflammatory activity in certain experimentally-induced inflammations. Cryogenine is an unusual anti-inflammatory agent since it is an alkaloid - all of the commonly used anti-inflammatories (aspirin, phenylbutazone, indomethacin, etc.) are organic acids.

The Effects Of Indomethacin On A Strain Of Fibroblasts Cultivated In Vitro, John Thomas Mccloskey

University of the Pacific Theses and Dissertations

Man has always searched for greater understanding of himself and his environment. As a result, much scientific investigation has been directed towards the understanding of the life process. In recent years, such scientific inquiry has become increasingly focused on the fundamental biochemical events taking place at the cellular, subcellular, and molecular levels. In the course of investigation into the nature of living things, research has often necessitated the development of new techniques and investigational tools to serve as experimental systems. Very often such new methods have made possible the discovery of previously unknown processes. One very interesting and useful investigational …

Representative Personality Dimensions Characteristic Of Different Occupational Choice In The Paramedical Field, Priscilla Bernadette Campos

University of the Pacific Theses and Dissertations

The purpose of this study was to ascertain if there are similarities and differences that differentiate one paramedical group from another in the realm of non-intellectual characteristics. Senior students and successful practitioners in four paramedical groups selected were Registered Nurse. Licensed Vocational Nurse, medical Assistant, and Dental Assistant.

Oral Stereognosis And Two-Point Discrimination Ability Of Anterior Tongue Thrusters And Normal Swallowers, Lawrence Jay Friedman

University of the Pacific Theses and Dissertations

The present study was designed to determine whether differences exist between frontal tongue thrusters and normal swallowers on tasks or oral stereognosis and two-point discrimination.

Differential Performance Of Stutterers And Fluent Speakers In The Perception Of Tachistoscopically Presented Visual Forms, Melvin Sander Cohen

University of the Pacific Theses and Dissertations

The present study was designed to answer the question: WIll stutterers perform differently from fluent speakers on a test of tachistoscopic recognition. It was hypothesized that persons exhibiting overt secondary symptoms of stuttering would demonstrate a visual field preference different from an age-matched group of fluent speakers who have no personal or familial history of stuttering.

The Dialysis Of Caffeine Through Selected Semi-Permeable Membranes, Paul James Perry

University of the Pacific Theses and Dissertations

Until the past few years, cellulose derivatives, (e.g., cellophane, collodion, and parchment) and animal membranes (e.g., goldbeater’s skin) have been the only dialysis membranes employed commercially. Cellophane has been used as the dialysis membrane in the artificial kidney since the machine’s inception in 1914. It continues to serve in this capacity, even though, in the last few years, attempts have been made to develop better films.

An appreciation of both the “solution theory” and the “pore theory” is in order for this discussion. By incorporating the dynamics of these theories in the techniques of membram formulation, improved membrane performance can …

A Study Of Families With Stress Related To The Care Of Children With Myelomeningocele, Janet L. Ferguson, Russel Tweed

Dissertations and Theses

This was an exploratory-descriptive study of fifty children afflicted with myelomeningocele, ages one through six, who were known to the Myelomeningocele Clinic of the Crippled Children’s Division. The study identified the degree of multiple physical, emotional, and environmental stress factors that families must be prepared to cope with. The study identified eleven factors felt to play an important role in family dynamics and how they related to the families response to their child with myelomeningocele. The factors were tested and found to be valid by the use of a pre-test on ten case records. Medical records were then obtained from …

Physiology Of A Uv-Induced, Coagulase-Positive, Avirulent Mutant Of Staphylococcus Aurues As Compared To Its Virulent Parent, James J. Bertucci

Master's Theses

No abstract provided.

The Cortical Nucleus Of The Amygdala As A Component In The Systems Regulating Gonadotrophin Secretion, Stuart Warren Smith

Dissertations

No abstract provided.

Radioautographic Incorporation Of Tritiated Lysine Into Protein Of Cells Of The Spermatogenic Cycle, Casimir F. Firlit

Dissertations

No abstract provided.

Hormonally-Induced Permeability Changes In Staphylococcus Aureus, Thomas J. Fitzgerald

Dissertations

No abstract provided.

Neurochemical Evidence For Cholinergic-Adrenergic Coupling In Mammalian Central Nervous System, Silas N. Glisson Iii

Dissertations

No abstract provided.

Investigation Of The Anticurare Effect Of Sodium Fluoride At The Mammalian Skeletal Neuromuscular Junction: A Dissertation, Robert S. Jacobs

Dissertations

No abstract provided.

Histochemical Localization And Identification Of Monoamine-Containing Cell Bodies In The Brain Stem Of The Squirrel Monkey (Saimiri Sciureus), Jack E. Hubbard

Dissertations

No abstract provided.

Protein Synthesis In Regenerating Wound Tissue And The Effect Of Thyroid Hormone, Cary Bruce Linksy

Dissertations

No abstract provided.

The Interaction Of Ethidium Bromide With Nucleic Acids, William Warren Martz

Dissertations

No abstract provided.

The Attempted Synthesis Of 4,4-Dimethyl-3-Dimethylamino-2,6-Cyclohexanedione Carboxamide, Roger Leith Cockerline

University of the Pacific Theses and Dissertations

The use of boron-containing amines for the amino alkylation of amides has been investigated in our laboratories with the aim of preparing compounds which could be used in neutron capture therapy. The purpose of this procedure is to achieve selective irradiation of a neoplactic growth by inducing radioactivity throughout that tissue. Although the results obtained in destroying tumors have not always been encouraging, they have been such - especially in cases not amenable to treatment by surgery or chemotherapy - that further research is warranted in order to develop drugs that can be used effectively in neutron capture therapy (Farr, …

Validation Of The Automated Readability Index For Use With Technical Materials, Leroy John Delionbach

College of Graduate Studies: Theses & Dissertations (1964–2006)

No abstract provided.

Release From Proactive Inhibition As A Function Of Pleasantness And Unpleasantness Of Encoded Verbal Materials, Fulton Cooper

College of Graduate Studies: Theses & Dissertations (1964–2006)

No abstract provided.

Glutaraldehyde As A Cold Sterilizing Agent For Endodontic Instruments, Gary Max Ritchie

Master's Theses

No abstract provided.

An Evaluation Of Occlusal Force Discrimination By Denture Wearers, Fred James Pacer

Master's Theses

No abstract provided.

The Effects Of Various Cation Concentrations On Salivary Amylase Activity, William Macdonald Reeves

Master's Theses

No abstract provided.

Correlations Between Behavioral Changes And Drug Induced Variations Of The Levels Of Mouse Brain Catecholamines And Serotonin, Daniel Leo Richardson

Master's Theses

No abstract provided.

Dentofacial Changes Of The Pre-Adolescent Child Produced By Heavy, Continuous Posterior Traction To The Maxillary Molars, Parallel To The Occlusal Plane: A Serial Cephalometric Investigation, Norman Lewis Sanders

Master's Theses

No abstract provided.

Some Physical Properties Of Cements Employed In The Cementation Of Orthodontic Bands, Jay R. Schauer

Master's Theses

No abstract provided.

Circadian Rhythm In The Labial Gingival Epithelium Of The Rat Maxillary Incisor, Paul A. Stutman

Master's Theses

No abstract provided.

Effect Of Vitamin D On Ribonucleic Acid Synthesis In Bone, Sue Ann Eckhardt Shelley

Master's Theses

No abstract provided.

Masticatory Rate As A Determinant Of The Rate Of Secretion Of Human Mixed Saliva, George Frederick Siersma

Master's Theses

No abstract provided.

A Morphologic Comparison Of The Periodontal Ligament Of Normal Versus Accelerated Erupting Teeth In Rats And Guinea Pigs, Andrew P. Trapani

Master's Theses

No abstract provided.