Medicine and Health Sciences Commons^™

Ai-Assisted Patient Assignment: Enhancing Workload Balance And Supporting Charge Nurse Decision-Making, Grace Mei, Brandon Bush Msn-Rn

Research Scholars

No abstract provided.

Operative Room Turnover And Efficiency Transitioning Between Robotic And Laparoscopic Surgery At Lehigh Valley Health Network, Part Of Jefferson Health, Liyana Paiker, Kelsey White Do, Mark Broadwin Md, Rovinder S. Sandhu Md, Jeffrey Glaser Md, Mba

Research Scholars

No abstract provided.

Analysis Of Care And Outcomes For Stage Iv Melanoma Patients At Lehigh Valley Topper Cancer Institute (2017-2023), Jake M. Panzer, Suresh G. Nair Md, Melissa Kratz Rn, Msn, Aocn

Research Scholars

No abstract provided.

Impella 5.5 Total Implant Outcomes For The Past 4 Years, Grace Perez, Jonathan Nelson, Bryan D. Nelson Mba, Cphq, Nrp, James K. Wu Md

Research Scholars

No abstract provided.

Management Of Hospitalized Patients With The West Nile Infection At Lehigh Valley Health Network, A Part Of Jefferson Health (Lvhn), Ta'niya Pleasant, Maham Rehman, Raul E Davaro Md

Research Scholars

No abstract provided.

Assessing The Impact Of A Pharmacy Driven Adult Mrsa Nasal Screening Protocol, Priyal Prabhu, Jarrod W. Kile Rphd, Golda Peysakhova Pharmd, Kathryn Zaffiri Mph, Eric Young Md

Research Scholars

No abstract provided.

The Impact Of Vision Therapy On Post-Concussion Symptom Resolution, Priya Sandhu, Francesca Andronic Md, Hope Kincaid Mph, Cph, Mitch Daniel, Daniele Shollenberger Crnp, Mark Cipolle Md

Research Scholars

No abstract provided.

Assessing The Impact Of A Pharmacy Driven Adult Clostridioides Difficile Screening, Anya Sawhney, Jarrod W. Kile Rphd, Brooke Broczkowski Pharmd, Eric Young Md, Kathryn Zaffiri Mph, Golda Peysakhova Pharmd

Research Scholars

No abstract provided.

Retrospective Review Of Vaginal Cuff Recurrence Following Hdr Therapy Of Endometrial Or Uterine Cancer, Kaitlyn Shak, Melissa Kratz Rn, Msn, Aocn

Research Scholars

No abstract provided.

Population Health Analysis And Identifying Healthcare Need In Monroe County, Kayla Schankel, Lisa Keller Med

Research Scholars

No abstract provided.

A Review Of Actinomyces Cultures And Pathology Specimens At A Large Academic Institution, Amy Slenker Md, Alex Benjamin Md, Deepti Verma Md, Shae Duka Mph, Alison Sutter Mph, Divya Verma

Research Scholars

No abstract provided.

Impact Of Preconception Counseling On Rates Of Preterm Birth And Cardiac Events In Pregnant Patients With Underlying Cardiac Issues, Sienna Walenciak, Rachel Flanagan Do, Rijul Amin, Taylor Deannuntis Do, Ghamar Bitar Md, Hope Kincaid Mph, Cph, Terri Vian, Joanne Quiñones Md, Msce

Research Scholars

No abstract provided.

Sepsis Not Present On Admission Mortality Analysis: Insights From Squad Virtual Nurse Monitoring, Adelaide Weir, Courtney Moore Md, Lorraine Valeriano Bsn, Rn, Cnrn, Michael Blawn Bsn, Rn, Deborah Santos Bsn, Rn, Jessica Maher Adn, Rn, Ccrn, Timothy J. Friel Md, Matthew Mccambridge Md, Dana Peluso Lpn, Bs

Research Scholars

No abstract provided.

Oximetry Disparity Due To Skin Color, Sera Wambui Karanja, Kirth W. Steele Do

Research Scholars

No abstract provided.

Assessing Frontline Rehabilitation Clinician Engagement In Quality Improvement And Research: The Role Of Systems Thinking, Psychological Safety, And Advisory Board Support, Synthia Layous, Kasey Hutter Ms, Ccc-Slp, Michael Pechulis Dpt, Heather Monihan Pt, Dpt

Research Scholars

No abstract provided.

Mystery Archives: Administrative File Management & Retention, Mia Mancebo, Amy Kintz, Jonathan Davidson Mba, Mabc, Pmp

Research Scholars

No abstract provided.

Improving Efficiency And Cost Effectiveness In Radiology Services Within Urgent Care Imaging Services, Athon Ros, Drew Borger Cpa

Research Scholars

No abstract provided.

Complication Rates In Aortic Surgeries Using Deep Versus Moderate Hypothermic Circulatory Arrest, Sofia Velez, Sophia Gormas, Bryan D. Nelson Mba, Cphq, Nrp, James K. Wu Md

Research Scholars

No abstract provided.

Policy Brief: North Dakota Maternal Mortality Committee, Kilyn R. Parisien

Public Health Student Publications

The following policy brief was created to examine North Dakota policies that are specific to maternal mortality and morbidity reviews. The North Dakota Maternal Mortality Committee (NDMMRC) is responsible for conducting maternal mortality and morbidity reviews in the state of North Dakota. This brief is guided by policies from North Dakota and MMRC reviews from surrounding states to inform six recommendations intended that guarantee the highest quality data collection and data reporting on maternal mortality and morbidity.

Higher Mortality And Distinct Complications After Anterior Cervical Discectomy And Fusion In Dialysis Patients, Despite Improvements Over Prior Decade: A National Inpatient Study, Mitchell K. Ng, Leonidas E. Mastrokostas, Paul G. Mastrokostas, William A. Green, Joshua Mathew, Gregorio Baek, Yasmine Eichbaum, Yulia Lee, Morgan Hitchner, Jonathan Dalton, Adam Fano, Alec Giakas, Rajendra Singh, Brendan Reitman, Afshin E. Razi, Daniel R. Fassett, Alan S. Hilibrand, Alex R. Vaccaro, Christopher K. Kepler, Gregory D. Schroeder, Andrew P. Alvarez

Rothman Institute Papers

Introduction: Dialysis patients undergoing anterior cervical discectomy and fusion (ACDF) face elevated perioperative risk due to complex comorbidities. This study aimed to (1) identify associations between dialysis status and perioperative complications after ACDF, (2) quantify differences in length of stay (LOS), hospitalization costs, and discharge disposition, and (3) provide a contemporary national benchmark for outcomes in this high-risk population. Materials and Methods: The 2016–2022 National Inpatient Sample was queried for adult elective ACDF cases. Dialysis dependence was identified through International Classification of Diseases-10 codes for end-stage renal disease with hemodialysis or peritoneal dialysis. Demographics, comorbidities, complications, LOS, costs, and discharge …

Utilizing Data To Inform Educational Decision Making, Andrew Blum, Kerri Green Edd, Ms

Research Scholars

No abstract provided.

Simbinder-If: Structure-Aware Antibody Affinity Optimization Via Efficient Preference Learning, Xinyan Zhao, Yi-Ching Tang, Rivaaj Monsia, Victor J Cantu, Ashwin Kumar Ramesh, Siyu Yang, Xiaozhong Liu, Zhiqiang An, Xiaoqian Jiang, Yejin Kim

The Brown Foundation: Institute of Molecular Medicine

Motivation: Antibody therapeutic efficacy depends on high-affinity target engagement, yet laboratory affinity maturation is slow and costly. Most protein language models (PLMs) lack explicit training for high affinity, and current preference optimization methods introduce computational overhead without clear affinity improvements. Therefore, structure-aware and parameter-efficient approaches for antibody affinity optimization are urgently needed.

Results: We propose SimBinder-IF, a structure-aware antibody optimization model trained by freezing the Evolutionary Scale Modeling inverse folding (ESM-IF) structure encoder and fine-tuning only its decoder via Simple Preference Optimization (SimPO) to prefer stronger binders. In generalization tests across seven held-out complexes (93 477 mutants), SimBinder-IF shows a …

Dnp Final Report: Improving Length Of Stay Outcomes Using Structured Barrier Rounds: A Quality Improvement Project, Martha Kwamboka Apella

DNP Final Reports

Prolonged length of stay (LOS) in the acute care setting is a challenging issue driven by multiple factors. Increased LOS is associated with mortality, hospital-acquired infections, patient safety events, functional impairment, decreased quality of life, social isolation, and increased cost of care. The causes of increased LOS in the medical-surgical unit are unclear, necessitating an evidence-based project to address the problem. The purpose of this quality improvement initiative was to implement structured interdisciplinary barrier rounds and evaluate their effect on LOS, opportunity days, and estimated cost of care in a medical-surgical unit. The facility complex care coordinator (CCC) was identified …

Dupilumab For Patients With Allergic Fungal Rhinosinusitis, Amber U Luong, Joshua M Levy, Sarah K Wise, Joseph K Han, Mamoru Yoshikawa, Luo Zhang, Rodney Schlosser, Prerna Ranganathan, Paula Dakin, Jennifer Maloney, George D Yancopoulos, Andrew P Fontenot, Neelam A Phadke, Lacey R Robinson

The Brown Foundation: Institute of Molecular Medicine

Background: Allergic fungal rhinosinusitis (AFRS) is a severe subtype of chronic rhinosinusitis characterized by fungal hypersensitivity and accentuated type 2 inflammation. Dupilumab-a fully human mAb blocking IL-4/13, approved for type 2 inflammatory diseases, including chronic rhinosinusitis with nasal polyps-may benefit patients with AFRS.

Objective: We sought to understand the effect of dupilumab in AFRS.

Methods: In this phase 3 trial, patients with AFRS age ≥6 years were randomized to dupilumab or matched placebo for 52 weeks. The primary end point was Lund-Mackay computed tomography score, quantifying sinus opacification, at 52 weeks. Secondary end points were multiplicity-controlled and hierarchically tested.

Results: …

Effects Of Non-Surgical Periodontal Therapy On Dental Plaque Microbiome, Qingguo Wang, Bing-Yan Wang, Derek Wilus, Hua Xie

Faculty, Staff and Student Publications

Periodontitis, a chronic inflammatory disease affecting approximately 40% of U.S. adults aged 30 years and older, is characterized by dysbiosis of the dental plaque microbiome. However, although scaling and root planing (SRP) is the cornerstone of periodontal treatment, its effects on the taxonomic composition and functional potential of the dental plaque microbiome remain incompletely understood. In this study, we used whole-metagenome shotgun sequencing to characterize taxonomic composition and functional potential in dental plaque microbiomes collected from 39 patients with Stage II or III generalized periodontitis before and 3–4 months after SRP. Consistent with clinical improvement, periodontal therapy significantly reduced probing …

Availability Of Cannabinoid-Infused Products In Corner Stores In Franklin Park, Allentown, Abigale Brosious, Joselyn Correa-Melendez Dhsc, Mph, Kimberly C. Brown Md

Research Scholars

No abstract provided.

Beyond Visual Inspection: Evaluating The Role Of Borescope Technology In Detecting Internal Contamination Of Reprocessed Surgical Instruments, Charlotte Annes, Adrienne Bell Bba, Cspdt, Robin Tannous Bsn, Rn, Cnor, Jonathan T. Berback Mph, Cic

Research Scholars

No abstract provided.

Loss Of Nemp1 Disrupts Female Meiosis And Activates A Conserved Atm-Chk2 Checkpoint, Bilal Ahmad Hakim, Yonit Tsatskis, Ling Zhang, Esther Choi, Ying Zhang, Didier Hodzic, Que Wu, Muyun Zhang, Maryam Pashaei, Kyungwon Ha, Jannette Rusch, Julie A Brill, Miguel Angel Brieño-Enríquez, Andrea Jurisicova, Helen Mcneill

2020-Current year OA Pubs

Female germ cells must preserve the integrity of their genome and generate genetic diversity via meiotic recombination. This challenging process is error prone. Highly conserved checkpoint pathways detect errors in recombination and DNA damage, inducing the death of defective oocytes. Nuclear Envelope Membrane Protein (NEMP) homologs are highly conserved proteins critical for fertility in flies, worms, fish and mice. They localize to the inner nuclear envelope where they provide mechanical support. However, why NEMP homologs are specifically required for fertility is still unclear. Using both Drosophila and mouse models, we establish that loss of NEMP homologs leads to activation of …

Dnp Final Report: Enhancing Self-Regulated Learning And Metacognition For First-Semester Undergraduate Nursing Students, Carla S. Biondillo

DNP Final Reports

Background. First-year undergraduate nursing students often struggle to adapt their learning strategies to the higher-order thinking and clinical reasoning demands of nursing education. Ineffective study habits, low academic self-efficacy, and limited self-regulated learning (SRL) skills are consistently identified as predictors of attrition, which ranges from 20–50% nationally and internationally.

Purpose. At an academic medical center in rural East Texas, first-semester students report academic overwhelm and inadequate study strategies, consistent with national trends. A structured, evidence-based faculty coaching intervention targeting SRL and metacognition was found to be feasible within the collaborative, student-centered organizational culture.

Methods. A quality improvement (QI) design …

Dnp Final Report: Community-Based Advance Care Planning Education For Older Adults: A Quality Improvement Project, Teresa Hill

DNP Final Reports

Background: Advance care planning (ACP) supports patient autonomy and promotes care aligned with individual values and preferences. Despite these benefits, fewer than half of adults aged 50–80 have completed formal ACP documentation, and community-dwelling older adults rarely engage in ACP before serious illness, representing a persistent gap in early engagement.

Purpose: This quality improvement (QI) project evaluated the effectiveness of a community-based ACP educational intervention in improving ACP knowledge, confidence, and engagement among older adults.

Methods: A nurse facilitator trained in the Five Wishes framework delivered a structured, 60-minute ACP workshop at a senior center in North Texas. A pre–post …