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Jefferson Alumni Bulletin – Volume Xlii, Number 4, Summer 1993

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLII, Number 4, Summer 1993

The development of surgery for heart disease, page 6

Refining the heart-lung machine, page 9

Training surgical residents, page 10

Counseling in family medicine, page 10

Volunteer care in Swaziland, page 10

Paleoradiology of the prehistoric Australian aborigines, page 11

Vaccine therapy of melanoma, page 12

Biliary radiology and T tube design, page 13

Familial patterns of ovarian carcinoma, page 15

The importance of treating diabetic retinopathy, page 16

Investigators identify key protein causing heart muscle damage after heart attack, page 18

Croce wins Mott Prize, page 19

Westermark given …

Department Of Radiology-Annual Report-July 1, 1992 To June 30, 1993, David C. Levin

Department of Radiology Administrative Documents and Reports

Department of Radiology Annual Report, July 1, 1992 to June 30, 1993. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States. 85 pages.

Transcript Of The Interview With Dr. James Quisenberry, James E. Quisenberry, Shirley Gish

Louise Caudill Oral History Collection

A transcript of an oral history with Dr. James Quisenberry, conducted by Shirley Gish, about his recollection of Dr. Louise Caudill.

Transcript Of Interview With Dr. Louise Caudill And Susie Halbleib (Interview 6), Claire Louise Caudill, Susie Halbleib, Shirley Gish

Louise Caudill Oral History Collection

A transcript of the second interview of Dr. Louise Caudill and Susie Halbleib, conducted by Shirley Gish, about Dr. Caudill's life and career.

Transcript Of The Interview With Jane Caudill, Jane E. Caudill, Shirley Gish

Louise Caudill Oral History Collection

A transcript of an oral history with Jane Caudill, conducted by Shirley Gish, about her recollection of Dr. Louise Caudill and the community of Morehead, Kentucky during the early half of the 20th century.

Transcript Of The Interview With Sister Jean Francis, Jean Francis, Shirley Gish

Louise Caudill Oral History Collection

A transcript of an oral history with Sister Jean Francis, conducted by Shirley Gish, about her recollection of Dr. Louise Caudill and her efforts to bring a hospital to the community of Morehead, Kentucky.

Transcript Of The Interview With Bob Bishop, Robert S. Bishop, Shirley Gish

Louise Caudill Oral History Collection

A transcript of an oral history with Bob Bishop, conducted by Shirley Gish, about his recollection of Dr. Louise Caudill and the community of Morehead, Kentucky during the early half of the 20th century.

Ua66/14/4 Kentucky Partnership Newsletter, Vol. 1, No. 3, Kentucky Partnership For Farm Family Health & Safety

University Organizations

Newsletter created by and about the Kentucky Partnership for Farm Family Health & Safety.

Helping To Harm? The Ethical Dilemmas Of Managing Politically Sensitive Data, Sylvie C. Tourigny

Center for the Study of Ethics in Society Papers

Presented to the WMU Center for the Study of Ethics in Society - March 19, 1993.

Suggested Reference Ranges In Clinical Chemistry For Apparently Healthy Males And Females Of Pakistan., Ayesha Molla, Mohammad Khurshid, William T. Manser, Rukhsana Lalani, Anis Alam, Zubaida Mohammad

Department of Pathology and Laboratory Medicine

Abstract

Seven hundred and eighty six apparently healthy males (418) and females (368) aged 0-69 years were randomly selected for estimation of reference ranges of 24 serum analytes at the clinical chemistry laboratory of The Ago Khon University Hospital (AKUH). Of the total study samples, 56% (439/786) were in the poediatric age group (0-14 years) and 44% (347/786) in the adult (1 5_60 years) group. Beckman Astra Ideal Autoanalyzer was used for all the estimations. Moon and standard deviations (SD) were calculated for each of the age groups. Reference ranges were calculated following standard methods of the International Federation of …

Cloning And Characterization Of Subunits Of The T-Cell Receptor And Murine Leukemia Virus Enhancer Core-Binding Factor., Shuwen Wang, Qing Wang, Barbara E. Crute, Irena N. Melnikova, Susanna R. Keller, Nancy A. Speck

Dartmouth Scholarship

Moloney murine leukemia virus causes thymic leukemias when injected into newborn mice. A major determinant of the thymic disease specificity of Moloney virus genetically maps to the conserved viral core motif in the Moloney virus enhancer. Point mutations introduced into the core site significantly shifted the disease specificity of the Moloney virus from thymic leukemia to erythroid leukemia (N.A. Speck, B. Renjifo, E. Golemis, T.N. Fredrickson, J.W. Hartley, and N. Hopkins, Genes Dev. 4:233-242, 1990). We previously reported the purification of core-binding factors (CBF) from calf thymus nuclei (S. Wang and N.A. Speck, Mol. Cell. Biol. 12:89-102, 1992). CBF binds …

Lithium Phthalocyanine: A Probe For Electron Paramagnetic Resonance Oximetry In Viable Biological Systems., K. J. Liu, P. Gast, M. Moussavi, S. W. Norby, N Vahidi, T Walczak

Dartmouth Scholarship

Lithium phthalocyanine (LiPc) is a prototype of another generation of synthetic, metallic-organic, paramagnetic crystallites that appear very useful for in vitro and in vivo electron paramagnetic resonance oximetry. The peak-to-peak line width of the electron paramagnetic resonance spectrum of LiPc is a linear function of the partial pressure of oxygen (pO2); this linear relation is independent of the medium surrounding the LiPc. It has an extremely exchange-narrowed spectrum (peak-to-peak line width = 14 mG in the absence of O2). Physicochemically LiPc is very stable; its response to pO2 does not change with conditions and environments (e.g., pH, temperature, redox conditions) …

Aggressive Angiomyxoma Of Vulva, Farrukh Aijaz, Shahid Pervez, Shehnaz Wasti, Sheema H. Hassan

Department of Pathology and Laboratory Medicine

No abstract provided.

Narrative Skills In 4-Year-Olds With Normal, Impaired, And Late-Developing Language, Rhea Paul, Rita L. Smith

Communication Disorders Faculty Publications

Two groups of children who were slow in expressive language development (SELD) at age 2 and a matched group of toddlers with normal language were re-evaluated at age 4. Assessment included measures of productive syntactic skills in spontaneous speech and narrative abilities in a standard story retelling task. Four-year-olds who continued to perform below the normal range in sentence structure production scored significantly lower than their normally speaking peers on all measures of narrative skill. Children who were slow to begin talking at age 2 but who, by age 4, had moved into the normal range in basic sentence structure …

Immunocompromise In Gnotobiotic Pigs Induced By Verotoxin-Producing Escherichia Coli (O111:Nm), Jane Christopher-Hennings, Joann A. Willgohs, David H. Francis, Usha A. K. Raman, Rodney A. Moxley, David J. Hurley

School of Veterinary and Biomedical Sciences: Faculty Publications

A verotoxin-producing Escherichia coli serotype O111:NM strain (strain 10049; verotoxin 1 positive) persistently infected experimentally inoculated gnotobiotic pigs, causing attaching-effacing intestinal lesions and chronic diarrhea. Experiments were performed to determine whether persistent infection might be associated with immunocompromise of the host by this organism. Pigs inoculated with this strain had a significant reduction in peripheral blood lymphocytes and lower antibody titers to sheep erythrocytes compared with control pigs. Compared with pigs given a verotoxin-negative pathogenic strain of the same serotype (O111:NM, strain 2430), pigs inoculated with the verotoxin-positive strain had lower peripheral lymphocyte counts and proliferative responses to concanavalin A, …

Early Adolescent Family Formation, Lisa J. Crockett

Department of Psychology: Faculty Publications

In the United States, adolescent family formation has been considered a major social problem since the late 1970s. The sources of concern are multiple. First, teenage childbearing is associated with risks for the mother and her child, including health problems, reduced life chances, and a greater likelihood of living in poverty. Second, a large and increasing proportion of births to teenagers are nonmarital; this appears to compound these risks. Third, the rate of teenage childbearing in the United States far exceeds those in other Western, industrialized countries (Alan Guttmacher Institute, 1986). The high rate of adolescent pregnancy in the United …

Ihs Indirect Costs Study, Native American Consultants, Inc.

Native Health Database Full Text

This study defines, documents, and analyzes the administrative and management costs (overhead) of the Indian Health Service (IHS) that are incurred in providing services to American Indians and Alaska Natives (AI/ANs).

Estimation Of The Incidence Of A Rare Genetic Disease Through A Two-Tier Mutation Survey, R Chakraborty, M R Srinivasan, S Raskin

Faculty, Staff and Student Publications

Recent attempts to detect mutations involving single base changes or small deletions that are specific to genetic diseases provide an opportunity to develop a two-tier mutation-screening program through which incidence of rare genetic disorders and gene carriers may be precisely estimated. A two-tier survey consists of mutation screening in a sample of patients with specific genetic disorders and in a second sample of newborns from the same population in which mutation frequency is evaluated. We provide the statistical basis for evaluating the incidence of affected and gene carriers in such two-tier mutation-screening surveys, from which the precision of the estimates …

Sequencing Of Cdna From 50 Unrelated Patients Reveals That Mutations In The Triple-Helical Domain Of Type Iii Procollagen Are An Infrequent Cause Of Aortic Aneurysms., Gerard Tromp, Yuli Wu, Darwin J. Prockop, Swarna L. Madhatheri, Caren Kleinert, James J. Earley, Jiapiao Zhuang, Orjan Norrgård, R. Clement Darling, William M. Abbott, C. William Cole, Pekka Jaakkola, Markku Ryynanen, William H. Pearce, James S.T. Yao, Kari Majamaa, Stanton N. Smullens, Zoran Gatalica, Robert E. Ferrell, Sergio A. Jimenez, Charles E. Jackson, Virginia V. Michels, Michael Kaye, Helena Kuivaniemi

Department of Biochemistry and Molecular Biology Faculty Papers

Detailed DNA sequencing of the triple-helical domain of type III procollagen was carried out on cDNA prepared from 54 patients with aortic aneurysms. The 43 male and 11 female patients originated from 50 different families and five different nationalities. 43 patients had at least one additional blood relative who had aneurysms. Five overlapping asymmetric PCR products, covering all the coding sequences of the triple-helical domain of type III procollagen, were sequenced with 28 specific sequencing primers. Analysis of the sequencing gels revealed only two nucleotide changes that altered the structure of the protein. One was a substitution of threonine for …

Tuberculous Mastitis Mimicking Malignancy--A Case Report With Review Of Literature, M Y. Sheikh, T A. Rana, M U. Islam

Department of Radiology

No abstract provided.

Transcript Of The Interview With Lucille Caudill, Lucille Caudill Little, Shirley Gish

Louise Caudill Oral History Collection

A transcript of an oral history with Lucille Caudill Little, conducted by Shirley Gish, about her recollection of Dr. Louise Caudill and the community of Morehead, Kentucky during the early half of the 20th century.

Transcript Of Interview With Dr. Louise Caudill, Susie Halbleib, And Dr. Travis Lockhart, Claire Louise Caudill, Susie Halbleib, Travis Lockhart, Shirley Gish

Louise Caudill Oral History Collection

A transcript of the second interview of Dr. Louise Caudill and Susie Halbleib, conducted by Shirley Gish, about Dr. Caudill's life and career.

Regulation Of Human Lung Fibroblast Alpha 1(I) Procollagen Gene Expression By Tumor Necrosis Factor Alpha, Interleukin-1 Beta, And Prostaglandin E2., Arturo Diaz, Elena Munoz, Rosemary Johnston, Joseph H. Korn, Sergio A. Jimenez

Department of Medicine Faculty Papers

We investigated the participation of prostaglandin (PG) E2 in the regulation of the alpha 1(I) procollagen gene expression by tumor necrosis factor alpha (TNF alpha), and interleukin-1 beta (IL-1 beta) in normal adult human lung fibroblasts. TNF alpha (100 units/ml) and IL-1 beta (100 units/ml) stimulated the production of PGE2 and caused a dose-dependent inhibition of up to 54 and 66%, respectively, of the production of type I procollagen. Preincubation of cultures with indomethacin partially reversed the inhibition of procollagen production induced by the cytokines. Cytokine-stimulated endogenous fibroblast PG accounted for 35 and 68% of the inhibition induced by TNF …

Ua66/4/2 Ceremony Of Capping & Pinning, Wku Dental Hygiene

WKU Administration Documents

Program from capping & pinning ceremony.

Ua66/14/3 Nursing Pinning Ceremony, Wku Nursing

WKU Administration Documents

Pinning ceremony program listing graduates of the WKU Nursing program.

Rapid Assessment Of Drug Susceptibilities Of Mycobacterium Tuberculosis By Means Of Luciferase Reporter Phages, William R. Jacobs Jr., Raul G. Barletta, Rupa Udani, John Chan, Gary Kalkut, Gabriel Sosne, Tobias Kieser, Gary J. Sarkis, Graham F. Hatfull, Barry R. Bloom

School of Veterinary and Biomedical Sciences: Faculty Publications

Effective chemotherapy of tuberculosis requires rapid assessment of drug sensitivity because of the emergence of multidrug-resistant Mycobacterium tuberculosis. Drug susceptibility was assessed by a simple method based on the efficient production of photons by viable mycobacteria infected with specific reporter phages expressing the firefly luciferase gene. Light production was dependent on phage infection, expression of the luciferase gene, and the level of cellular adenosine triphosphate. Signals could be detected within minutes after infection of virulent M. tuberculosis with reporter phages. Culture of conventional strains with antituberculosis drugs, including isoniazid or rifampicin, resulted in extinction of light production. In contrast, …

Ua66/14/3 Nursing Pinning Ceremony, Wku Nursing

WKU Administration Documents

Pinning ceremony program listing graduates of the WKU Nursing program.

Information Interface - Volume 17, Issue 3 - May/June 1993, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

Cryptococcus Neoformans Serotype Groups Found In Clinical And Environmental Isolates, John Clauson

Masters Theses & Specialist Projects

Cryptococcus neoformans is an encapsulated yeast responsible for severe meningoencephalitis. The importance of epidemiological studies on cryptococcosis has increased since the beginning of the AIDS epidemic. C. neoformans exists in two varieties containing four serotypes, C. neoformans var. neoformans (serotypes A and D) and C. neoformans var. gattii (serotypes B and C). Locally C. neoformans var. neoformans has been associated with pigeon feces during those months having an average temperature of 64.2°F j(17.8°C) and above. Clinical and environmental isolates of C. neoformans obtained from regional hospitals and environmental samplings, respectively, have been grouped into their variety status utilizing canavanine-glycine-bromthymol blue …

Reasonable Children, Michael Pritchard

Center for the Study of Ethics in Society Papers

Presented to the WMU Center for the Study of Ethics in Society - May 19, 1993.