Medicine and Health Sciences Commons^™

Ua66/4/2 Ceremony Of Capping & Pinning, Wku Dental Hygiene

WKU Administration Documents

Program from capping & pinning ceremony.

Ua66/14/3 Nursing Pinning Ceremony, Wku Nursing

WKU Administration Documents

Pinning ceremony program listing graduates of the WKU Nursing program.

The Effect Of Selenium Supplementation On The Immune Response Of Mice With Experimental Chagas' Disease, Cindy Calisi, Lynette Brooks

Mahurin Honors College Capstone Experience/Thesis Projects

No abstract provided.

Retiree/Part-Time Farmer Killed When Run Over By Bush Hog, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Tractors/Logging

A 64-year-old male retiree and part-time farmer was killed when he fell from his tractor and was run over by the edge of the bush-hog attachment. The victim had been repairing a tractor tire earlier in the day. He was apparently trying to drive the tractor into a garage when he lost control and fell or was knocked from the tractor seat to the ground, falling between the tractor and the bush hog. The KY FACE investigator concluded that, in order to prevent similar occurrences, tractor operators should:

• Retrofit tractors with operator restraint systems (seatbelts) and Roll Over Protective Structures …

Information Interface - Volume 20, Issue 2 - May/June 1995, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

Diagnostic Evaluation Of Pleural Effusion And The Role Of Needle Pleural Biopsy, S F. Hussain, S Mujahid, J A. Khan

Section of Pulmonary & Critical Care

No abstract provided.

An 800-Year-Old Physician – Surgeon Researcher Who Fits The Neuro Mold, George M. Austin

The Dr. George M. Austin Neurology Research Collection

Dr. Austin's copy of the McGill Neurosurgical Reunion Book of Abstracts. The file contains the Authors Index and Dr. Austin's abstract. Presented May 1995 for the Aneurysm-Stroke Research Foundation. Dr. Austin's complete copy of the book is available for use at Loma Linda University, Department of Archives and Special Collections.

The Oral Physician... Creating A New Oral Health Professional For A New Century, David A. Nash

Oral Health Science Faculty Publications

No abstract provided.

Transcriptional Activity Of Core Binding Factor-Alpha (Aml1) And Beta Subunits On Murine Leukemia Virus Enhancer Cores., Ari L. Zaiman, Amy F. Lewis, Barbara E. Crute, N. A. Speck, Jack Lenz

Dartmouth Scholarship

Core binding factor (CBF), also known as polyomavirus enhancer-binding protein 2 and SL3 enhancer factor 1, is a mammalian transcription factor that binds to an element termed the core within the enhancers of the murine leukemia virus family of retroviruses. The core elements of the SL3 virus are important genetic determinants of the ability of this virus to induce T-cell lymphomas and the transcriptional activity of the viral long terminal repeat in T lymphocytes. CBF consists of two subunits, a DNA binding subunit, CBF alpha, and a second subunit, CBF beta, that stimulates the DNA binding activity of CBF alpha. …

Heterozygosity Mapping Of Partially Congenic Lines: Mapping Of A Semidominant Neurological Mutation, Wheels ( Whl), On Mouse Chromosome 4, Patrick M. Nolan, Patricia J. Sollars, Barbara A. Bohne, Warren J. Ewens, Gary E. Pickard, Maja Bucan

School of Veterinary and Biomedical Sciences: Faculty Publications

We identified a semidominant, chemically induced, mouse use mutation with a complex array of abnormal behaviors including bidirectional circling and hyperactivity, abnormal circadian rhythmicity and abnormal responses to light. In this report, we genetically and phenotypically characterized the circling/ waltzing component of the abnormal behavior. We mapped the locus controlling this trait by heterozygosity mapping of partially congenic lines carrying the mutagenized chromosome outcrossed to different inbred strains for three generations. Analysis of 68 PCR-based markers in 13 affected individuals indicated that the mutant locus, named Wheels (Whl), resides in the subcentromeric portion of mouse chromosome 4. The …

Learning Lessons From Sunk Costs, Brian H. Bornstein, Gretchin B. Chapman

Department of Psychology: Faculty Publications

Study participants rated the quality of several arguments for continuing an original plan in sunk cost situations in order to (a) avoid wasting resources, (b) learn to make better decisions, (c) punish poor decision making, and (d) appear consistent. The lesson-learning argument was perceived as most appropriate when adult teachers taught lessons to others, the original decision was carelessly made, or if it consumed comparatively more resources. Ratings of the lesson-learning argument were higher for teacher-learner than for adult-alone situations, regardless of whether the learner was a child or an adult. The implications for improving decision making and judging whether …

Altered Platelet Activating Factor Metabolism In Insulin Dependent Diabetes Mellitus, R A. Memon, S A. Saeed, A Jabbar, A Jafri, A H. Gilani, S Saleem, H Akbani

Department of Biological & Biomedical Sciences

Diabetes mellitus is associated with several abnormalities of platelet function. Recent studies have shown that the blood level of platelet activating factor (PAF), a potent inducer of platelet aggregation, is elevated in insulin dependent diabetes mellitus (IDDM) and remains unchanged in non-insulin dependent diabetes mellitus (NIDDM) patients. However, the mechanism of this increase in PAF levels has not been determined. In this study we have measured the activity of plasma PAF acetylhydrolase (an enzyme that regulates PAF levels) and lipoprotein levels in control subjects and diabetic patients. The data presented show that plasma PAF acetylhydrolase activity is significantly decreased in …

Prison Employee Killed In Tractor Rollover, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Tractors/Logging

A 36-year-old male prison recreation director was killed in a tractor rollover incident. The victim was driving the tractor down a sloping, S-curved driveway when he lost control. The tractor went over an embankment, rolled one-half turn, and came to rest on the victim. It was not equipped with a Rollover Protective Structure (ROPS) or a seatbelt. The victim was pronounced dead at the scene by the county coroner. In order to prevent similar incidents, the KY FACE investigators concluded that:

• Tractors should be retrofitted with Roll Over Protective Structures and seatbelts.
• Employers should provide tractor operation training by safety …

Increased Alpha 1(I) Procollagen Gene Expression In Tight Skin (Tsk) Mice Myocardial Fibroblasts Is Due To A Reduced Interaction Of A Negative Regulatory Sequence With Ap-1 Transcription Factor., Neena Philips, Reza I. Bashey, Sergio A. Jimenez

Department of Medicine Faculty Papers

The TSK mouse, a model of fibrosis, displays exaggerated connective tissue accumulation in skin and visceral organs including the heart. To study the mechanisms of myocardial fibrosis in TSK mice, we established several strains of TSK mice myocardial fibroblasts in culture and examined the regulation of collagen gene expression in these cells. These strains displayed increased collagen gene expression in comparison with myocardial fibroblasts established from normal mice. On an average, the TSK myocardial fibroblast cultures showed a 4-fold increase in collagen synthesis and 4.4- and 3.6-fold increases, respectively, in alpha 1(I) and alpha 1(III) collagen mRNA steady state levels. …

Farmer Killed When Run Over By Tractor In Barn, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Tractors/Logging

A 62-year-old male farmer was killed inside his barn on a Saturday afternoon after starting his tractor from a standing position. The victim was demonstrating recent repairs to the tractor for his brother-in-law; a new battery and starter had been installed. Standing beside the tractor, the victim reached for the ignition switch to turn the tractor on. The tractor was in gear; when he turned the key the tractor lurched forward, running over the victim, who died moments later. The KY FACE investigators concluded that, to prevent similar occurrences, farmers and other tractor operators should:

• Never attempt to start a …

Pbn, Dmpo, And Pobn Compositions And Method Of Use Thereof For Inhibition Of Age-Associated Oxidation, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Compositions containing as the active ingredient a spin-trapping reagent, preferably α-phenyl butyl nitrone (PBN) or spin-trapping derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient are disclosed for treating or preventin symptoms associated with aging or other conditions associated with oxidative tissue damage. Other spin-trapping agents can also be used, such as 5,5-dimethyl pyrroline N-oxide (DMPO) or α-(4-pyridyl 1-oxide)-N-tert-butylnitrone (POBN), and other spin-trapping derivatives thereof. These compositions and methods are useful in the treatment of age-related disorders, pre-surgical and/or pre-anesthetic preparation or administration of chemotherapeutic agents, and in the treatment of disorders or trauma of the brain, …

Protein-Peptide Interactions Analyzed With The Yeast Two-Hybrid System, Meijia Yang, Zining Wu, Stanley Fields

Dartmouth Scholarship

The yeast two-hybrid system was used to screen a library of random peptides fused to a transcriptional activation domain in order to identify peptides capable of binding to the retinoblastoma protein (Rb). Seven peptides were identified, allof which contain the Leu-X-Cys-X-Glu motif found in Rb-binding proteins, although their activity in the yeast assay variedover a 40-fold range. Mutagenesis of the DNA encoding two of these peptides followed by screening in the two-hybrid systemallowed the delineation of residues apart from the invariant Leu, Cys and Glu that affect binding to Rb. Binding affinities of a peptide and one of its variants …

Apparatus And Method For Noninvasive Chemical Analysis, Robert A. Lodder

Pharmaceutical Sciences Faculty Patents

A method and apparatus are provided for magnetohydrodynamic acoustic-resonance, near-IR spectroscopy. The method includes a step of applying to a subject under study a magnetic field having a strength between 2,00-10,000 gauss, near-IR radiation having a wavelength between 800-3,000 nm and an acoustic wave having a frequency between 10 khz-1 Mhz. The method also includes the steps of inducing vibration of ions in the magnetic field and detecting an electric wave generated magnetohydrodynamically by the acoustic wave induced vibration of the ions. Next is the collecting of the electrical, acoustical and near-IR spectra and the analyzing of the collected spectra. …

Mid-Atlantic Ethics Committee Newsletter, Spring 1995

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

The Beat Newsletter, College Of Medicine

The Beat Newsletter

This is the April, 1995 edition of the Frederick P. Whiddon College of Medicine's newsletter - The Beat.

Contents include:

• Site specific drug delivery
• Herpes simplex virus
• Biotechnical services
• DNA repair enzymes
• NIH grant to study fetal development
• USA stroke center

Ua66/13/3 Health Link, Vol. 1, No. 1, Wku Public Health

WKU Administration Documents

Newsletter created by and about the WKU Public Health department.

Ua66/14/4 Kentucky Partnership Newsletter, Vol. Ii, No. 8, Kentucky Partnership For Farm Family Health & Safety

University Organizations

Newsletter created by and about the Kentucky Partnership for Farm Family Health & Safety.

Factors Which Predict The Initiation And Use Of Alcohol In Rural Adolescents, Charlotte Swint

Masters Theses & Specialist Projects

The purpose of this research was to determine whether a selected group of factors are significant when trying to predict the use of alcohol by adolescents who live in rural areas. This research is important because most of the studies concerning drug and alcohol use in adolescents have focused on adolescents who live in urban areas. The results of such studies may not be generalizable to rural populations. The factors investigated included the following: availability of alcohol, peer influence, parental influence, tobacco use, gender, and grade level. These factors were chosen based on their inclusion in four prominent theories regarding …

Communications Connection - Vol.2, No. 4 - Spring 1995, Nova Southeastern University

Communications Connection

No abstract provided.

Basics Of Research (Part 2): Reviewing The Literature, Eric Davis, Cheryl Thompson, Edward A. Panacek

Journal Articles: College of Nursing

No abstract provided.

Partnerships Between Community Residents And Professionals: Issues Of Power And Social Class Across The Lifespan Of Neighbourhood Organizations, Barbara Derksen, Geoffrey Nelson

Psychology Faculty Publications

We described a qualitative sutdy of four neighbourhood centres jointly created by a sponsoring agency and community members to prevent problems in the lives of chidlren and adults in these neighbourhoods. Individual and focus group interviews with staff, community members, and other agency workers were used to develop an understanding of issues involved at various stages across the lifespan of these settings. Two tensions noted in this process were between community members and professionals from the sponsoring organization and between lower-class and middle-class community members. We discuss the implications of these findigns for practice in community development.

Health Attitude Changes As A Result Of Participating In A Worksite Prenatial Education Program, Vickie Gibson

Masters Theses & Specialist Projects

The purpose of this study was to determine whether differences in health beliefs exist between participants attending worksite prenatal education classes and participants receiving only prenatal education self-help materials. A multiple treatment study was performed on a sample of convenience of 169 women enrolled in Fruit of the Loom's worksite prenatal education program. Group 1 subjects received class and materials while Group 2 subjects received materials only. Study participants were asked to complete an 18-item Likert scale questionnaire prior to enrolling in the program and again upon completion. Sixty-two subjects completed both the pre- and posttest questionnaires. Analysis of covariance …

Athletic Identity And Sport Orientation Of Adolescent Swimmers With Disabilities, Jeffrey J. Martin, Carol Adams Mushett, Kari L. Smith

Kinesiology, Health and Sport Studies

Measures of athletic identity and sport orientation, developed from self-schema theory, social role theory, and achievement motivation theory, were used to examine international adolescent swimmers with disabilities. The multidimensional Athletic Identity Measurement Scale (Brewer, Van Raalte, & Linder, 1993) was used to assess self-identity, social identity, exclusivity, and negative affectivity. The Sport Orientation Questionnaire (Gill & Deeter, 1988) measured competitiveness, win orientation, and goal orientation. Swimmers reported (a) a strong self-identity, (b) a moderate to strong social identity, (c) negative affectivity with lower levels of exclusivity, (d) strong competitiveness and goal orientation, and (e) moderate win orientation. Self-identity was correlated …

A Change Of Il-2 And Il-4 Production In Patients With Helicobactor Pylori Infection, X. G. Fan, Javed Yakoob, X. J. Fan, P. W. N. Keeling

Section of Gastroenterology

Helicobactor pylori is the most common cause of gastroduodenal inflammation. However, the exact immune pathogenesis is not fully understood. To look for evidence of the immunological mechanism in H. pylori associated disease, we measured cytokine interleukin-2 (IL-2) and IL-4 levels produced by peripheral blood lymphocytes (PBL) and gastric biopsies in 20 subjects with or without H. pylori infection. H. pylori can stimulate IL-2 and IL-4 production from PBL in H. pylori negative as well as H. pylori positive individuals. The spontaneous IL-2 production by PBL and gastric biopsies was greater (p < 0.0025, <0.001)in H. pylori negative individuals than that in H. pylori infected patients. Increased IL-4 levels from PBL in H. pylori infected patients were found in the presence of H. pylori (p < 0.0025). An increased spontaneous production of IL-4 from gastric biopsies was also observed in H. pylori infected patients (p < 0.025). In conclusion, an enhanced type 2 cytokine production was observed in H. pylori infected patients, which may be responsible for H. pylori chronic infection.

Polyclonal Mycobacterium Avium Infections In Patients With Aids: Variations In Antimicrobial Susceptibilities Of Different Strains Of M. Avium Isolated From The Same Patient., C Fordham Von Reyn, Nicholas J. Jacobs, Robert D. Arbeit, Joe N. Maslow, S Niemczyk

Dartmouth Scholarship

Broth microdilution MICs were determined for pairs of strains isolated from five AIDS patients with polyclonal Mycobacterium avium infection. Four (80%) of the five patients were infected simultaneously with strains having different antimicrobial susceptibility patterns. These findings have implications for the interpretation of susceptibility data in M. avium prophylaxis and treatment trials.