Medicine and Health Sciences Commons^™

30-Day Oral Acetaminophen Tolerance In Adult Horses, Sarah E. Foreman

Celebration of Learning

There are no controlled studies of acetaminophen toxicity in horses. The objective was to test the hypotheses that oral acetaminophen administered at a dosage 25% higher than that sometimes used in horses would result in measurable hepatic toxicity as seen in humans and other species. Six healthy adult horses were administered 25 mg/kg acetaminophen powder in corn syrup twice daily for 30 days. Three other horses served as negative controls receiving only corn syrup. Jugular venous blood samples were obtained on days 7 and 1 before treatment; on treatment days 1, 2, 5, 8, 12, 15, 19, 22, 26 and …

Managing Patient Expectations With Implant Treatment, Daniel B. Kamran, Mark Booth Dds, Eduardo Gonzalez Dds, Ed Shaw Dds

Excellence Day

This patient came to University of the Pacific, Arthur A. Dugoni School of Dentistry to get implants and implant crowns to improve his smile, replacing his upper partial denture. Different approaches were made by the faculty to arrive at best outcomes, which took four years for the patient to receive the treatment he wanted. This abstract will further detail how the treatment was conducted and the results afterwards.

Rapid Placement And Anatomical Sculpting Of Hardened Posterior Composite, Patrick Roetzer, Mahek Pipalia, Krunali Kapadia

Excellence Day

Posterior composites have long had a reputation for being difficult and time consuming in clinical practice. In addition to this reputation, it has been noted that recurrent caries and in general failure of these restorations prematurely has been a problem. Relative to amalgams, posterior composites have vexed even good clinical dentist. This video presentation illustrates techniques that not only save time but also create more predictable high-quality restorations.

A Modified “Wound Healing” And Hypoxia Model In Vitro, Schuyler G. Tang, Isabel Kwon, Marie M. Tolarova, Mirek Tolar

Excellence Day

Closing a wound may resemble some aspects of fusion of embryonic processes during development of face. In addition, both are sensitive to oxygen supply.

Effect Of Folate On Endoplasmic Reticulum Stress Caused By Hypoxia, Paul Kim, Shub Dhillon, Mahsa Mortazavi, Marie M. Tolarova, Mirek Tolar

Excellence Day

Endoplasmic reticulum (ER) stress is involved in the pathogenesis of congenital cardiac defects, intrauterine growth restriction, craniofacial anomalies, and many common diseases. The purpose of this study was to test if folic acid (FA) can mitigate ER stress or improve recovery of cells from ER stress.

Integrating Interprofessional Education Through Service-Learning: Continued Multidisciplinary Collaboration For Student-Led Volunteer Healthcare Event, Sunny Jisun Lee, Heather Leo, Sachan Bhatia, Byron Chou, Christine E. Miller

Excellence Day

SCOPE (Student Community Outreach for Public Education) at University of the Pacific (UOP), Arthur A. Dugoni School of Dentistry sponsored the 25th Annual Senior Smiles Health & Wellness Fair in its clinic, located in San Francisco on April 21^th, 2018. More than 105 San Francisco’s senior citizens with limited access to health care attended this event. As a continuation of last year’s Senior Smiles & Wellness which pioneered the launch of Interprofessional education (IPE) activities, SCOPE provided various health screenings to the senior attendees in partnership with Dugoni’s sister schools UOP Audiology and Physical Therapy program as well …

Biomarkers Of Orthodontic Tooth Movement, Ellie Schwartz, Shubdeep Kaur, Mahsa Mortazavi, Marie M. Tolarova, Mirek Tolar

Excellence Day

Orthodontic tooth movement is made possible by remodeling of the alveolar bone process. Bone remodeling is carried out by cellular activities of osteoclasts, osteoblasts, and osteocytes. This in turn is regulated by a number of extracellular factors including growth factors, cytokines, chemokines, hormones and biomechanical force. This review is focused on chemical biomarkers characterizing orthodontic tooth movement.

Geometric Morphometric Shape Assessment Of Juvenile Mandibles, Tiffany Tran, Vicki Lo, Hee Soo Oh, Gary D. Richards

Excellence Day

OBJECTIVES: We explore three-dimensional data to delineate idiosyncratic and progressive growth variation in 6.0-8.0 year old mandibles (n=45).

Variation In And Assessment Of Inferior Alveolar Nerve Block Landmarks In Children And Adolescents, Soi Park, Younjin Lee, Younyoung Lee, Tiffany Tran, Gary D. Richards

Excellence Day

OBJECTIVES: In earlier work (Lambert et al., 2017) we demonstrated the efficacy of new landmarks for inferior alveolar nerve (IAN) block injections. While the latter study focused on adult morphology, the landmarks were shown to be effective in cases where the M³/₃ were present but unerupted. Based on these result a question arose as to their applicability of the landmarks to children and adolescents, given the known changes in mandibular foramen position during growth. Here we quantify the position of the mandibular foramen relative to standard landmarks during growth and assess the new landmarks applicability for IAN …

Shear Bond Strength Of Nine Dual Cured Build-Up Materials And A Light-Curing Adhesive System On Dentin, Deepali Malla, Karen Schulze, Patrick Roetzer

Excellence Day

The purpose of this study was to measure the shear bond strength of nine different commercially available dual cured core build-up materials on human dentin in conjunction with a light curing adhesive system. The null hypothesis was that there is no statistical significant difference among the core build-up systems.

Root Analogue Implant Creation: Establishing Procedures For The General Dentist, Alicia Hazdovac, Sarah Osborne, Gary D. Richards

Excellence Day

The possibility of replacing damaged teeth with custom-made root analogue implants was initially suggested around 1969 and reintroduced by Lungren et al. in 1992. The latter authors created custom implants in titanium and reported good osteointegration and aesthetic results. Following this effort there has been an increasing focus on custom root analogue implants as a replacement for ‘screw-type’ implants. Given the availability of software to manipulate 3D image data and the rapid rise of 3D printing technology, the question arises as to whether a general dentist can produce their own implants. Here we test the feasibility of practitioners producing custom …

The Role Of Aryl Hydrocarbon Receptor (Ahr) Signaling Pathway In Oral Squamous Cell Carcinoma (Oscc): Preliminary Results., Renee Lee, Cui Xu, Leticia Ferreira, Ana Carolina Morandini, Erivan Ramos-Junior

Excellence Day

OBJECTIVES: A large number of experimental and clinical studies suggest that the origin of oral squamous cell carcinoma (OSCC) is linked to environmental carcinogenesis (tobacco, alcohol). Among these environmental factors, cigarette smoking is the most studied and has been associated with increased susceptibility to OSCC by activating signaling pathways responsible for cancer initiation and progression. Besides nicotine, cigarette smoke also contains aryl hydrocarbon receptor (AhR) agonists, such as dioxin and benzo(a)pyrene. Aberrant AhR expression and AhR pathway activation are involved in several types of cancer. However, the relationship between AhR pathway activation and oral cancer progression is still unclear.

Genes Associated With Mandibular Prognathism In The Chinese Population, Jacqueline Payne, Marie Tolarova M.D., Ph.D., D.Sc.

Excellence Day

Mandibular prognathism (MP) is the relationship of the mandible anteriorly positioned in relation to the cranial base. The prevalence of MP in Asians is estimated to be 15%, whereas American and European descent exhibit a 5% prevalence. Orthodontic treatment is lengthy and challenging, and severe cases require surgical intervention. However, when a treatment is planned well, the outcomes are predominantly successful. It has been known that genetics are involved in the etiology of prognathism and that greater genetic contribution corresponds to greater challenges to treatment. Thus, there is a desire to determine genes involved in the etiology of prognathism.

Socio-Economic Factors That May Contribute To Etiology Of Orofacial Clefts., Shubdeep Kaur, Mahsa Mortazavi, Geethapriya Kumar, Marie M. Tolarova

Excellence Day

Association of socio-economic status (SES) with congenital anomalies and diseases has been studied for many years. Under the umbrella of SES are several factors and they vary in different parts of the world due to differences in climate, ethnicity, and culture.

The purpose of this systematic review was to determine associations between various risk factors related to SES and prevalence of orofacial clefts (OFC).

Orofacial Clefts In The Middle Eastern Countries – A Systematic Review, Mahsa Mortazavi, Marie M. Tolarova

Excellence Day

The purpose of this study was to determine the prevalence of orofacial clefts (OFC) in the Middle East. Recent studies of etiology of OFC in populations of different countries characterized by a specific cultural, religious, or socioeconomic status revealed that different environmental and genetic factors may participate in their etiology.

Distribution Of Malocclusions In Middle East Countries: A Systematic Review., Mahsa Mortazavi, Marie M. Tolarova

Excellence Day

High prevalence, multifactorial etiology and the effect on the esthetic, function and quality of life, make the malocclusions as a subject of debate for many years. Regarding the important role of malocclusion in treatment approaches, policy making in health organizations and understanding the etiology factors, this literature review was performed with the purpose of determining the prevalence and distribution of malocclusion in region of the Middle East.

Case Report: Use Of Non-Ridgid Connector, Veniamin Dronov

Excellence Day

Long span bridges have a tendency to experience harmful stress due to the increased surface area and of the restoration. These stresses can cause several problems including failure of the restoration or cause significant discomfort to the patient.

Treatment Planning: Facially Generated, Digitally Guided, Manually Fabricated Smile Design, Neal Atul Patel

Excellence Day

A clinical case presentation of a smile design that consists of 10 units of minimally invasive indirect restorations.

Longitudinal Cephalometric Study Of Untreated Subjects With Different Facial Types, Divya Vadlamudi, Shalaka Desai, Ambika Arun, Bhuvaneshwari Tatikonda, Shreya Penukonda, Apurva Dabak, Cindy Kim, Mai Nguyen, Heesoo Oh

Excellence Day

To examine the craniofacial morphological characteristics of different facial types based on vertical dysplasia in untreated subjects from the ages of 8 to 18.

Changes In Airway Volume In Adult Patients Following Orthodontic Treatment With Premolar Extractions Versus Non-Extraction, Sunny Jisun Lee, Allison Kawata, Hayoung Michael Shin, David Chambers, Joorok Park, Heesoo Oh

Excellence Day

Recent concerns about the prevalence of obstructive sleep apnea (OSA) and its negative sequelae have led to investigations of how manipulation of the dentofacial complex may affect airway problems. CBCT can be used to measure airway dimensions of patients. Extraction of premolars is indicated as part of orthodontic treatment for patients who have severe crowding or protrusion of incisors. Some have suggested that the reduction in arch circumference after premolar extraction would lead to decreased airway volume, which may predispose a patient for sleep disordered breathing (SDB). The purpose of this study was to determine whether there is a significant …

Changes In Cephalometric Measurements In Adult Patients Following Orthodontic Treatment With Premolar Extractions Versus Non-Extraction, Byron Chou, David Dang, Adrienne Joy, David Chambers, Joorok Park, Heesoo Oh

Excellence Day

Extraction of premolars is indicated as part of orthodontic treatment for patients who have severe crowding or protrusion of incisors. CBCT can be used to locate cephalometric landmarks in 3D. The purpose of this study was to determine whether there are differences in sagittal, transverse, and vertical skeletal and dental dimensions for adult patients who were treated with premolar extractions in conjunction with orthodontic treatment compared to those who received orthodontic treatment without extractions.

Condylar Degeneration In Patients With Dental Open Bite Versus Skeletal Open Bite Utilizing Cbct, Alex Rauchle, Alston Trinh, Linda Phi, Brad Albertson, Joorok Park, Heesoo Oh

Excellence Day

Idiopathic condylar resorption (ICR) is a condition in which either one or both condyles undergo degeneration. Bilateral TMJ involvement presents as a clockwise rotation of the mandible in the posterior-inferior direction, resulting in an anterior open bite. The purpose of the study was to assess TMJ condylar degeneration in dental open bites compared to skeletal open bites.

Student’S Perceptions Of Spiritual Preparedness And Contribution To Their Community Following An Emergency Preparedness Interprofessional Collaborative Practice Simulation, Elizabeth J. Scott, Ronda M. Christman, Sonia K. Wrate, Rebecca Retzer, Laura Racovita, Faith A. Laughlin, Leslie Ann Schwarazer, Cynthia F. M. Gettys, Maureen Baksh-Griffin

Adventist Human-Subject Researchers Association

This presentation highlights findings from a study exploring student perceptions of spirituality and contributing to their community after participating in an emergency preparedness interprofessional simulation. Mixed methods were utilized and an online survey was emailed to a convenience sample (N=338). The majority self-reported they can better contribute to their community.

Student’S Understand Their Care Role And Have The Ability To Provide Care Following A Multi Patient Collaborative Practice Simulation, Barbara James, Ronda M. Christman, Christina Shrode, Laura Racovita-Szilagyi, Caroline T. Mcarthur, Sonia Wrate, Christy Showalter, Leslie Ann Schwarazer, Michael Liedke, Christine A. Moniyung, Jill Buchholz

Adventist Human-Subject Researchers Association

This presentation highlights findings from a study exploring student perceptions after participating in a Multi Patient Interprofessional Collaborative Practice simulation. Mixed methods were utilized and an online survey was emailed to a convenience sample (N = 81). The majority self-reported they understand their care role and abilities to provide care.

An Assessment Of Maternal Mortality In Papua New Guinea: An Explanatory Sequential Mixed Methods Approach, Jennifer Litau

Adventist Human-Subject Researchers Association

Research into the serious manifestation of maternal mortality in Papua New Guinea is essential for formative knowledge and intervention. Explanatory sequential mixed methods approach employed first involved SPSS analyses of Gulf Provincial Hospital’s obstetric data revealing high rates of home deliveries by mothers. Interviews in high incidence communities provided explanations and mortality experiences.

A Critical Analysis Of The Mental Health First Aid Educational Intervention Developed By The National Council For Behavioral Health, Padma P. Tadi Uppala

Adventist Human-Subject Researchers Association

In Berrien County, Michigan, the priority health need identified among students was mental health. The objective of this study is to critically analyze the Mental Health First Aid educational intervention developed by the National Council of Behavioral Health for family members and health professionals. Spirituality was identified as a negative factor affecting mental health on the survey. It is important for mental health professionals to acknowledge the protective role of spirituality against mental illness as pointed out in the scientific literature.

The Association Of The Cumulative/Lifetime Duration Of Breast Feeding And The Development Of Post Menopausal Breast Cancer. Results From Adventist Health Study - 2., Sozina Katuli, Synove Knutsen Dr, Raymond Knutsen Dr., Ronald Mataya Dr., Oda Keiji, Gary Frasier Dr.

Adventist Human-Subject Researchers Association

We modeled breast cancer in a Cox proportional hazard regression analysis and found 25% lower risk for those who initiated breastfeeding than those who never breastfed. There was a threshold effect for duration of breastfeeding and increased risk for family history of breast cancer, recent HRT use, and higher education.

Student Perception Of Biblical Worldview And Personal/Professional Impact Of The Sau Higher Education Biblical Foundation Course Design Model, Lilly Tryon, Ronda Christman

Adventist Human-Subject Researchers Association

This presentation highlights findings from a study exploring student perceptions of taking a course designed with the Biblical Foundation of Faith in Learning Concept Map (BFFL-CM). Mixed methods were utilized, an online survey was emailed, with N=140 sample. The majority felt they benefited from taking the course with the BFFL-CM.

P-10 Time Spent Studying, On Social Media, And Spirituality: Nursing Students’ Perceptions, Ronda M. Christman, Elizabeth J. Scott, Eunice Muriu, Cynthia Booher, Ronald Mitchell

Adventist Human-Subject Researchers Association

This presentation highlights findings from a multi-university study exploring students’ perceptions of studying, social media, and spirituality. Mixed methods were utilized, an online survey was emailed, with N=88 sample size. Over half (55%) have a personal daily devotional 4 – 7 days/week.

Understanding Qualitative 3d Shape From Texture And Shading, Benjamin Kunsberg, Steven W. Zucker

MODVIS Workshop

No abstract provided.