Medicine and Health Sciences Commons^™

Effects Of A Novel Botanical Supplement On Glycemic Variability And Postprandial Glucose Response, Nicole Stevens

Oxford ICSB

Mulberry leaf extract high in the iminosugar 1-deoxynojirimycin (DNJ) has been shown in previous studies to inhibit glycosidase enzyme activity. A novel supplement including mulberry leaf extract, berberine and cinnamon extract was evaluated in a two-cohort study using endpoints of glycemic variability, postprandial glucose response, fasting glucose, fasting insulin, and safety markers. In the first cohort (n=15), these endpoints were determined over two weeks by continuous glucose monitoring (CGM) and blood/urine analyses in healthy adults. Approximately half of the participants (n=7) took a dosage of 250 mg prior to each meal, and the other participants (n=8) took 500 mg before …

The Impact Of Covid-19 On The Supply Chain And Quality Of Botanical Ingredients, Stefan Gafner

Oxford ICSB

Examples from the past show that a supply chain disruption, or a series of such disruptions, generates sudden spikes in consumer demand, and that abrupt, unplanned changes to the supply and demand in botanical materials lead to an increase in adulteration and fraud. When this happens due to simultaneous interruptions of numerous ingredients based on a global pandemic, as in the case of COVID-19, it is predictable that unscrupulous suppliers and sellers of botanical ingredients will attempt to take advantage of supply shortages by manufacturers of herbal medicines and dietary supplements to sell them lower-quality or sometimes adulterated materials.

Among …

Immulina Enhances Host Resilience Against Influenza Virus-Induced Illness In A Prodromal Mouse Model: Part B – Changes In Viral Load And Clinical Signs Of Infection, Kashif Shamim, Tahir Mir

Oxford ICSB

The University of Mississippi Botanical Dietary Supplements Research Center is performing research on the potential use of Limnospira (formally Arthrospira) to enhance resilience against influenza viral infection. Limnospira is a cyanobacterium that has been used as a food for centuries and more recently as a popular health supplement. A commercial extract called Immulina has been developed that concentrates the level of immunomodulatory activity due to Braun-type lipoproteins – compounds that activate immune pathways through a toll-like receptor (TLR) 2-dependent mechanism. Although oral ingestion of Immulina has been reported to exhibit a protective effect against subsequent H1N1 influenza A (IfA) …

138 - Does The Sensory Room Work?, Chantal Martinez, Megan Keach, Ryan Mcdonald, Hollie Errington

GREAT Day Posters

Mental health in college students has been a continuous issue with many students suffering from anxiety and depression. Many students are particularly vulnerable to stress, which is correlated to academic underperformance, failure to fulfill academic obligations, and problematic health behaviors, such as substance abuse. A higher perceived stress level in university students can cause a poorer quality of life, well-being, and sleep quality. It is important to recognize coping strategies to relieve these mental health stressors. There are many resources available on campus to help students in regards to mental health, but the newly developed sensory room located in Monroe …

253 - Ambient Identity Cues Within Digital Spaces: How Institutional Identities Influence Text And Image Selection, Rachel Denzler, Daniel Regan, Kaitlyn Britt, Michelle Costa, Charlotte Sutphin

GREAT Day Posters

Belonging is a basic human need with substantial impact on overall health and well-being (e.g., Baumeister & Leary, 1995). The presence of ambient identity cues, socially symbolic objects that communicate stereotypes about group members inhabiting a given environment, can powerfully impact perceptions of belonging and interest (Cheryan et al., 2009). Our previous work examined the presence of identity cues in academic digital spaces regarding text analyses. Through examining 36 institutional website pages, we conducted a qualitative assessment of identity cues via Linguistic Inquiry and Word Count (Pennebaker et al., 2001). The current work analyzes the images within the institutional websites, …

305 - Cannabis Use Among Gender And Sexual Minority College Students, Karla Mejia, Samantha Degrandis, Madison James

GREAT Day Posters

Previous research has found an increased risk for substance use in sexual and gender minority (SGM) identifying individuals. Broadly, within the age groups of college students and emerging adulthood, heightened rates of marijuana use have been observed for individuals endorsing a sexual and/or gender minority identity (Dunbar et al., 2022). The current study will examine associations between college students' rates of marijuana use and the endorsement of a SGM identity status. Participants (N = 150; Age = 19.2, SD = 1.7) reported on their sexual and gender identity and completed self-report measures, including the Difficulties in Emotion Regulation Scale (DERS; …

311 - Sibling Dyads’ Perceptions Of Their Relationship In Adolescence And Early Adulthood, Isabelle Cook, Adele Beltrani, Emma Richards, Natalie Thurston

GREAT Day Posters

As part of a longitudinal study, we examined siblings’ perceptions of their relationship in adolescence and early adulthood. Twenty-five sibling dyads completed questionnaires about their relationship during adolescence and early adulthood. The adolescent questionnaire was an age-adjusted questionnaire developed for use in the study; it included five scales (Asymmetry, Intimacy, Prosocial/Harmony, Relational Aggression, and Conflict). For the early adulthood phase, we used the Adult Sibling Relationship Questionnaire (Stocker et al., 1997); it included 12 scales (Similarity, Intimacy, Quarreling, Affection, Antagonism, Admiration, Emotional Support, Competition, Instrumental Support, Domination, Acceptance, and Knowledge). Correlations among scales on the questionnaires reveal considerable coherence in …

Açaí Fruit Pulp And Supplement Extracts: Potential Induction Of Cyp Enzymes And P-Gp/Oatp-B Transporters, Kelli Mcdonald

Oxford ICSB

Euterpe oleracea Mart., commonly known as açaí, is among the top 40 botanicals currently used in the United States. Its presence in food products and botanical supplements is growing exponentially. To better ascertain potential açaí-drug interactions, we are analyzing the effects of açaí extracts on CYP induction and P-gp/OATP-B drug transporters. Certified organic açaí fruit powder from Mountain Rose (MR) Herbs (Eugene, OR, USA) and dietary supplement capsules containing aqueous extracts of Euterpe oleracea Mart. (açaí) fruit from Nature’s Way (Green Bay, WI, USA) and Natrol (Chatsworth, CA, USA) were obtained. The Mountain Rose powder is representative of what is …

Prediction Of Clinically Relevant Botanical-Drug Clearance Interactions For Boswellia Serrata Extract Using Sandwich-Cultured Human Hepatocytes., Amy Roe

Oxford ICSB

Boswellia serrata extract (BSE) is used in dietary supplements for its anti-inflammatory properties. There are reports in the scientific literature that BSE has the potential to inhibit CYP450 enzymes. We have shown that sandwich-cultured human hepatocytes (SCHH) are an excellent model for predicting clinically relevant botanical-drug interactions (BDI) since they integrate metabolism and transport. When using SCHH the BDI potential with BSE appears low; however, our previous work did not include an assessment of CYP450 induction potential. We present an intrinsic clearance approach using SCHH to evaluate an overall net effect (inhibition and induction) of BDI potential with BSE. SCHH …

Usp Monographs For Quality Control Of Different Ginsengs, Cuiying Ma

Oxford ICSB

Ginseng species are members of the genus Panax and are characterized by the presence of ginsenosides. American ginseng, Asian ginseng, Tienchi ginseng, and red (steamed) Asian ginseng roots and their extracts are very popular ingredients of dietary supplements. Quality control of ginseng dietary supplement products and differentiation of different ginseng articles are important for guaranty of quality and correct labeling. USP monographs for different ginsengs provide quality control procedures with suitable reference standards (RS) to help ensure correct and qualified ginseng ingredients are used.

USP ginseng monographs include both UHPLC and HPTLC identification tests of ginsenosides, which can efficiently identify …

More Than Just A Number: Utilizing Ccs And Conformational Space Analysis To Characterize Unknowns In Complex Extracts, Rachel A. Harris

Oxford ICSB

Natural products from plants, either as pure compounds or as prepared extracts, are widely recognized for their near unlimited potential due to their unmatched and rich chemical diversity. Challenging aspects in the use of natural products include the recognition that unknown compounds are not included in spectral databases, have no chemical standards, and discrimination of structurally similar isomers requires knowledge of isomer presence and potentially difficult and time-consuming chromatographic separations.[FS1] Ion mobility (IM) is a gas phase analytical technique that separates ions based on differences in their size, shape, and charge in the gas phase. Increasingly, IM is being utilized …

Cardiovascular Disease In The Active Service: Incidence Rates And Implications For Intervention, Sophie R. Vincent

Symposium of Student Scholars

Cardiovascular disease (CVD) is the number one cause of death in the United States. Common risk factors associated with CVD are obesity, hypertension, alcohol use, tobacco use, unhealthy diet, and physical inactivity. Other factors such as genetics, race, age, and gender also play a role in the development of CVD. Based on current literature, the increasing trend of obesity impacts even active-duty military service members who are paid to maintain their physical fitness. Due to the lack of literature surrounding incidences of CVDs in active service members, the present study provides insight into this topic. The present research conducted a …

Effect Of Virtual Dementia Tour On Prelicensure Student Nurses’ Attitudes Towards Dementia Care: A Quantitative Study Protocol, Kevin Alton

Symposium of Student Scholars

Background: With over six million Americans currently living with dementia, it is crucial for prelicensure nursing programs to prepare registered nurses to provide quality care to individuals with dementia and their caregivers. Due to the challenges associated with providing face-to-face clinical experiential learning, particularly during the COVID-19 pandemic, virtual simulation approaches are now being used as alternative or complementary clinical experiential teaching/learning methods.

Design: Quantitative Research

Purpose: To evaluate the effectiveness of the Virtual Dementia Tour on prelicensure student nurses' attitudes towards dementia care.

Methods: This study is nested in a larger ongoing multisite, mixed-methods crossover-experimental designed study that investigates …

The Influence Of Surgical Stress And Inflammatory Biomarkers On The Occurrence Of Postoperative Delirium, Kirsten Davis, Yulisa Flores

Symposium of Student Scholars

Research focusing on hypothermia has established a relationship between surgical stress and inflammatory biomarkers on delirium incidents in critically ill non-cardiac surgical patients. Unfortunately, postoperative delirium is a common complication after surgery and results in acute brain failure. Though the cause of delirium is still relatively unknown, systemic inflammation with neurological involvement is one of the leading etiologic theories. Another common complication in surgical patients is the occurrence of unplanned hypothermia during non-cardiac surgeries. For our study, we will be looking at two inflammatory biomarkers: C-reactive protein (CRP), and Interleukin 6 (IL-6). CRP is produced in the liver and is …

Employee Attrition: Analyzing Factors Influencing Job Satisfaction Of Ibm Data Scientists, Graham Nash

Symposium of Student Scholars

Employee attrition is a relevant issue that every business employer must consider when gauging the effectiveness of their employees. Whether or not an employee chooses to leave their job can come from a multitude of factors. As a result, employers need to develop methods in which they can measure attrition by calculating the several qualities of their employees. Factors like their age, years with the company, which department they work in, their level of education, their job role, and even their marital status are all considered by employers to assist in predicting employee attrition. This project will be analyzing a …

The Impact Of The Covid-19 Pandemic On Maternal Health Outcomes, Jaiden Outten, Afekwo Mary Ukuku Ph.D.

Symposium of Student Scholars

Title: The Impact of the COVID-19 Pandemic on Maternal Health Outcomes

Abstract

The COVID-19 Pandemic has disrupted access to maternal health services. Lockdowns, fear of contracting the disease, and limited access to healthcare services may have affected the overall well-being of expectant mothers and their newborns. Studies from previous infectious disease outbreaks have shown that adverse maternal outcomes have increased. Research is needed to determine the indirect impact the pandemic had on various areas of maternal health. The purpose of this study is to conduct a systematic literature review to understand the impact of COVID-19 on maternal health. A systematic …

The Relationship Amongst Sleep, Gestational Weight Gain, And Insulin Resistance During Pregnancy, Ami Eho

Symposium of Student Scholars

The Relationship Amongst Sleep, Gestational Weight Gain, and Insulin Resistance During Pregnancy

Authors: Ami Eho1, Dr. Janeen Amason2, Dr. Katherine H. Ingram3 (mentor)

INTRODUCTION: The Center for Disease Control and Prevention reports that 48% of pregnancies are affected by excessive weight gain. Gestational weight gain (GWG) is associated with adverse perinatal outcomes including insulin resistance, a precursor to type 2 diabetes. Short sleep duration and poor sleep quality are correlated with weight gain in general population but the relationship between sleep and weight gain during pregnancy is unclear. OBJECTIVE: To evaluate how sleep duration or sleep quality affect GWG and …

Unstable Politics, Empty Stomachs: Investigating The Relationship Between Political Instability And Food Insecurity, Andrew Lewis

Symposium of Student Scholars

Nowadays, food shortages are becoming more commonplace due to increasing costs and supply chain disruptions caused by the COVID-19 epidemic and other socioeconomic factors. Food security is a crucial public health issue that affects human well-being, health, and development on a global scale. The State of Food Security and Nutrition in the World report from 2021 estimates approximately 2.37 billion people suffered from a lack of food in 2020. In other words, 1 in 3 people could not access enough food (FAO et al., 2021). Food security is not only determined by natural factors but also by social factors such …

A Research Appraisal Of How Electronic Health Record Implementation Has Impacted Coding Efficiency​, Madeline Phillips, Jasmine Ware

ATU Scholars Symposium

This research project highlights the ways that coding efficiency has been improved in healthcare over the years, with an emphasis on EHR implementation. This research project references and analyzes trends concerning coding and the revenue cycle from both credible and reliable sources. In this research study, we will reference articles that analyze trends and create a visual understanding of the data collected. This study will highlight a broad spectrum of the impact of electronic health record implementation in the healthcare setting. (Tsai et al., 2020)

The Effects Of Artificial Insemination On Beef Cattle In The United States, Allee R. Sweeten, Abigail Shelnut, Madison Dickey

ATU Scholars Symposium

Artificial insemination (AI) is a reproductive procedure widely used in cattle industries and other livestock to increase pregnancy rates. Breeders must wait until the animals are in the estrus part of their estrous cycle to AI. Estrus synchronization is utilized to manipulate the estrous cycle to go into estrus or standing heat. AI is conducted by loading a semen straw into an inseminating gun, inserting the gun into the vagina of the heifer, and making sure it gets past the cervix by palpating with the other hand. Once past the cervix, the semen can be distributed in the heifer. AI …

Fighting Malnutrition In Kenya, Jessica Payton, Tara Ross, Adalyne Nehus

ATU Scholars Symposium

No abstract provided.

The Demographic Shift Of Males And Females In Veterinary Medicine, Dalton Tatum, Eddy Patterson, Mia C. Ratliff

ATU Scholars Symposium

The workforce in veterinary medicine saw a gender shift from a male dominated field towards women in the present day. This research aimed to determine why this shift occurred through demographic analysis and surveys to different job types in this career path. By using this data, the group determined that one of the biggest impacts of the shift is due to the very component that makes veterinary medicine such a tough field, and it is located at the graduate school entry level . The competitiveness level is intertwined through all of the data and leads to the conclusion that females …

The Synergistic Effect Of Loganetin And 5-Fluorouracil On The Carcinogenesis Of Glioblastoma Cancer Cells, Jonathan Wollenberg

ATU Scholars Symposium

Chemoresistance is a discouraging trend that affects chemotherapeutic agents like 5-fluorouracil (5-FU) and leads to decreased efficacy of treatment. This has led to numerous studies into compound synergism. Glioblastomas are a type of lethal cancer that has shown chemoresistance to therapeutic agents such as 5-fluorouracil. Being the most common and lethal primary brain tumor, research on mechanisms of growth inhibition is vastly important (Lustig, 2018). The purpose of this study was to analyze whether 5-fluorouracil and a compound named Loganetin could synergistically inhibit glioblastoma cancer cells. This specific study utilized an extract created from the Lonicera etrusca plant. It was …

Fast Detection Of Adulteration In Lavender Essential Oil Using A-Teem Multidimensional Spectroscopy, Jeffrey Juien

Oxford ICSB

Absorbance-Transmission Excitation Emission Matrix, or “A-TEEM” is a multimodal spectroscopic approach that incorporates UV/Vis and 3D fluorescence for a 2-in-1 measurement. This attractive methodology promotes a rapid and cost-effective alternative for analyses in areas as diverse as water treatment, food & beverage, natural products, and pharmaceuticals. One of the key attributes responsible for its appeal is the very low limit of detection, often in the parts-per-billion to parts-per-trillion range, which is several orders of magnitude better than competing technologies such as NIR, FT-IR, and Raman. In addition to having high sensitivity and specificity, A-TEEM has proven to be a robust …

Operation Supplement Safety Ingredient Database: A Comprehensive Encyclopedic Collection Of Ingredients, Andrea T. Lindsey

Oxford ICSB

Operation Supplement Safety (OPSS) is the Department of Defense’s (DoD) go-to program for anything related to dietary supplements (DS). OPSS partners with other federal departments, professional and academic institutions to provide the most current, evidence-based information, resources, and tools for education and decision-making. In March 2022, DoD Instruction (DoDI) 6130.06, Use of Dietary Supplements in the DoD was issued. It states that OPSS will maintain the official DoD Prohibited Dietary Supplement Ingredients List and provide DS educational training.

OPSS is developing a comprehensive ingredient database (OPSSID) that will list all ingredients (to include prohibited ones) found in DS, along with …

Supporting The Development Of Early Literacy For Children Using Augmentative And Alternative Communication (Aac), Logan Winter

Student Academic Conference

This literature review was completed to explore emerging literacy skills in children who use Augmentative and Alternative Communication (AAC) for communication purposes. This paper explored the differences in language and literacy learning for children who utilize AAC. For children in early developmental phases of language, AAC played a role in both receptive and expressive language. Skills learned in receptive and expressive language can be shaped into what is considered early literacy skills. Through findings by researchers and experts in the field of AAC and speech-language pathology this paper defined specific interventions and supports that can be implemented during the development …

Chemometrics: A Valuable Tool For Deriving Information From Complex Data Sets, James Harnly

Oxford ICSB

Chemometrics is a subset of machine learning which has been defined a set of advanced mathematical and statistical methods for the analysis of data. This defines many methods such as chemometrics, artificial neuro networks, support vector machines, and rule building expert systems. Chemometrics allows us to draw information from multivariate raw data, i.e., to discover patterns, causes of the patterns, and, with appropriate algorithms, the variance associated with the patterns. The most commonly used forms of chemometrics are principal components analysis (PCA for modeling) and partial least squares-discriminant analysis (PLS-DA for classification), unsupervised and supervised methods, respectively. In its simplest …

Rapid Simultaneous Quantitation Of Kavalactones And Flavokavains In Piper Methysticum Root By A-Teem Spectroscopy, James Kababick, Stacy Wise

Oxford ICSB

No abstract provided.

Investigating Differences In Iga Antibody Response Against Aspergillus Fumigatus In Wild Type And Tlr7 Protein Deficient Mice, Courtney Folk

Student Academic Conference

Aspergillus fumigatus is a commonly inhaled, respiratory fungal pathogen and an allergen found in flooded indoor environments, household dust, soil, and plant matter. While a competent immune system effectively clears the inhaled fungus, this same fungus poses a significant threat to weakened immune systems due to its potential to invade the lungs, bloodstream and brain tissue. The mouse genome is 99% similar to the human genome and can serve effectively model the effects of inhaled A. fumigatus (Guénet, 2005). Antibodies play a crucial role in neutralizing pathogens and in mediating an allergic response. In this study, we will investigate the …

Postpartum Health And Wellbeing, Tamara Black

Symposium of Student Scholars

Our project is testing the stress levels of women in postpartum. We developed surveys for women who have recently given birth and then do a two finger stress test.