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Articles 31 - 60 of 11706
Full-Text Articles in Medicine and Health Sciences
Effects Of Microgravity And Gamma Radiation On Biofilm Growth, Anya Pavlidis, Kaitlyn Mills Mills, Eva Mcclory, Grant Erlinder, Allen Qiu
Effects Of Microgravity And Gamma Radiation On Biofilm Growth, Anya Pavlidis, Kaitlyn Mills Mills, Eva Mcclory, Grant Erlinder, Allen Qiu
Discovery Day - Daytona Beach
Biofilms are collections of bacteria that commonly grow on a variety of surfaces. They are resistant to environmental impacts as bacteria fortify themselves to a surface. Biofilms are commonly found on Earth, but more problematically are also found on spacecraft. On the ISS biofilms have developed in spaces like the workout area, food spaces, and most concerning in the Water Recovery System (WRS). Biofilms tend to react differently to attempted cleaning methods in space than they do on Earth and can be located in extremely difficult to reach places. This study aims to explore the effects of gamma radiation on …
Effects Of Sleep Duration And Perceived Stress Of Reaction Time In Undergraduate Students, Caitlin Wescott, Edna Urrutia, Ryan F. Rednick, David Still
Effects Of Sleep Duration And Perceived Stress Of Reaction Time In Undergraduate Students, Caitlin Wescott, Edna Urrutia, Ryan F. Rednick, David Still
Discovery Day - Daytona Beach
Sleep deprivation and psychological stress are common among undergraduate students and can negatively affect cognitive performance. Reaction time is an important indicator of attention and processing speed and plays a critical role in both everyday activities, such as driving, and high-performance environments where rapid responses are required. This study aims to examine how sleep duration and perceived stress levels influence reaction time in undergraduate students. Participants will report their sleep duration and perceived stress levels through short surveys and wearable sleep data, while reaction time will be measured using a standardized computerized reaction time test. By comparing reaction time across …
Interactive Effects Of Tissue Temperature And Hydration State On Tendon Mechanical Properties Using A Chicken Drumstick Model, Makayla Maso, Kiara Maso, Mikayla Hulvey
Interactive Effects Of Tissue Temperature And Hydration State On Tendon Mechanical Properties Using A Chicken Drumstick Model, Makayla Maso, Kiara Maso, Mikayla Hulvey
Discovery Day - Daytona Beach
This study focused on the effects of temperature and hydration on tendon extensibility. Four experimental groups were tested using chicken leg tendons tested ex vivo: cold and dehydrated, cold and hydrated, warm and dehydrated, and warm and hydrated. Each treatment group was pulled with an increasing load and measured. It was hypothesized that the warm and hydrated test group would extend the furthest. This was based on studies citing increased bodily flexibility with increasing body temperature as well as stiffness at lower temperatures. Combining temperature and hydration state allowed for not only individual effects of variables to be tested but …
Steam Distillation Of Jasmine, Mikayla Hulvey, Meliah Martin
Steam Distillation Of Jasmine, Mikayla Hulvey, Meliah Martin
Discovery Day - Daytona Beach
This experiment aimed to isolate various components, including benzyl acetate, linalool, indole, and farnesene, from jasmine buds. The functional groups include an ester in benzyl acetate, an alcohol in linalool, an amine in indole, and alkenes in farnesene. Jasmine buds were combined with distilled water and steam distilled using a standard distillation apparatus. The distillate, containing hydrosol and trace amounts of essential oil, was then collected for extraction using methyl tert-butyl (MTBE) for a liquid-liquid extraction. The organic layer was then separated, washed using brine, dried over anhydrous sodium sulfate, and then transferred for later analysis. The essential oil obtained …
Numerical Analysis Of The Sir Model For Predicting Disease Spread, Victoria Gaibor, Isabel Tejada, Kate Moore
Numerical Analysis Of The Sir Model For Predicting Disease Spread, Victoria Gaibor, Isabel Tejada, Kate Moore
Discovery Day - Daytona Beach
This project, Numerical Solutions of the SIR Model for Predicting Disease Spread, investigates the application of numerical methods to analyze the dynamics of infectious diseases using the classical Susceptible–Infected–Recovered (SIR) model. The SIR model, a system of nonlinear ordinary differential equations, is widely used to describe how diseases such as COVID-19 propagate through a population. The primary objective of this study is to solve the SIR initial value problem using multiple numerical techniques, including Euler’s method, Runge–Kutta methods, and multistep methods, and to compare their accuracy and efficiency. The model is implemented using given initial conditions and parameters, and additional …
Simulating Pacemakers And Heartbeat Recovery Through Mathematical Modeling, Thomas Estrada, Jayla Edwards
Simulating Pacemakers And Heartbeat Recovery Through Mathematical Modeling, Thomas Estrada, Jayla Edwards
Discovery Day - Daytona Beach
Title: Simulating Pacemakers and Heartbeat Recovery Through Mathematical Modeling This study utilizes the Fitzhugh-Nagumo model to simulate cardiac electrical activity and the regulatory role of pacemakers through ordinary differential equations (ODEs). By defining the rate of change for membrane voltage, 𝑑𝑣/dt, and a recovery variable, 𝑑𝑤/dt, the model captures the heart's excitability and resting states. Central to the analysis is the stimulus current parameter, which represents the "kick" provided by a pacemaker to correct flatline conditions or weak heartbeats. Using Euler’s method for numerical integration, the research compares unstable cardiac rhythms against corrected periodic oscillations. Additionally, the project implements vector …
Finding And Using Validated Surveys In Health Science Research, Tracy Ashby
Finding And Using Validated Surveys In Health Science Research, Tracy Ashby
Library Class: Lunch & Learn
Join us as we introduce techniques for identifying and using validated surveys in health sciences research. Learn strategies for finding reliable, evidence-based measurement tools in the databases and gain tips on how to evaluate their quality and relevance.
Abstract Book (Pdf), Lsu Health School Of Medicine
Abstract Book (Pdf), Lsu Health School Of Medicine
Summer Research Internship Program
Abstract Book for the 20XX Summer Research Internship Program.
Participants are listed alphabetically by last name.
Accessibility statement: The attached document has been formatted to meet PDF/UA v1 standards.
A Phenomenological Study Of Parent Experiences During Transition From Early Intervention To School-Based Services, Kelly F. Gregoire, Halie Mayfield, Jeryl D. Benson, Johnna Estep
A Phenomenological Study Of Parent Experiences During Transition From Early Intervention To School-Based Services, Kelly F. Gregoire, Halie Mayfield, Jeryl D. Benson, Johnna Estep
Graduate Student Research Symposium
Abstract
Importance: Occupational therapy (OT) practitioners and members of the Early Intervention (EI) to school-based transition should understand the barriers to a successful transition to better advocate for their clients and tailor their involvement in the transition process.
Objective: To explore the lived experience of parents of young children participating in the transition process.
Participants: Fourteen parents of young children (ages 2.5-6 years) with a developmental disability.
Outcomes and Measures: Semi-structured interviews focusing on parent and family experiences with the transition process.
Results: Seven resulting themes emerged from the data representing parent perceptions related to their experience of the system. …
Awareness Of The Medicare Diabetes Prevention Program Among Healthcare Providers Caring For Older Adults, Anannya Pushkarna, Melanie Turk
Awareness Of The Medicare Diabetes Prevention Program Among Healthcare Providers Caring For Older Adults, Anannya Pushkarna, Melanie Turk
Graduate Student Research Symposium
Introduction:
Prediabetes is a prevalent condition among older adults and represents a crucial opportunity where early interventions can help prevent the onset of type 2 diabetes mellitus. Lifestyle modifications are first-line management. The Medicare Diabetes Prevention Program (MDPP), a 12-month lifestyle change program initiated in 2018, is fully covered by Medicare, yet uptake remains limited. This study assessed healthcare providers’ beliefs about prediabetes and awareness of the MDPP.
Methods:
A cross-sectional survey was administered electronically to a national sample of physicians, nurse practitioners (NPs), and physician assistants (PAs). Questions addressed beliefs about prediabetes, barriers to care, and knowledge/awareness of the …
Uncovering The Path To Diagnosis Among Adults With Attention-Deficit/Hyperactivity Disorder: A Constructivist Grounded Theory Mini-Study, Jeffrey D. Whitaker, Rick Zoucha, Melissa Kalarchian
Uncovering The Path To Diagnosis Among Adults With Attention-Deficit/Hyperactivity Disorder: A Constructivist Grounded Theory Mini-Study, Jeffrey D. Whitaker, Rick Zoucha, Melissa Kalarchian
Graduate Student Research Symposium
Abstract
Background: Attention-deficit/hyperactivity disorder (ADHD) often persists into adulthood, yet many adults are first diagnosed only after years of functional strain, compensation, and alternative explanations for their difficulties. Purpose: This study explored how adults first diagnosed with ADHD in adulthood described navigating the process of obtaining a formal diagnosis. Methods: A constructivist grounded theory mini-study was conducted with seven adults, ages 27 to 43, who reported receiving their first formal ADHD diagnosis at age 18 or later. Participants completed semi-structured Zoom interviews focused on early experiences, symptom interpretation, help-seeking, and formal assessment. Data were analyzed using initial, focused, and theoretical …
High Burden Of Elevated Fib-4 In Metabolically At-Risk Primary Care Patients: Simple Predictors To Guide Hepatic Fibrosis Triage, Ridwan Ademola Lawal, Fatimah Bello, Rashmee Patil, Juliana Yang
High Burden Of Elevated Fib-4 In Metabolically At-Risk Primary Care Patients: Simple Predictors To Guide Hepatic Fibrosis Triage, Ridwan Ademola Lawal, Fatimah Bello, Rashmee Patil, Juliana Yang
Research Symposium
Background: Metabolic dysfunction–associated steatotic liver disease (MASLD), including metabolic dysfunction–associated steatohepatitis (MASH), is a leading cause of chronic liver disease worldwide. Current guidelines recommend fibrosis-based risk stratification using noninvasive tools such as the Fibrosis-4 (FIB-4) index in patients with metabolic risk factors, followed by secondary assessment (e.g., transient elastography or enhanced liver fibrosis(ELF) testing) for those with elevated scores. However, data on the real-world prevalence of elevated FIB-4 in U.S. primary care populations, particularly in safety-net settings, and the downstream implications for fibrosis evaluation remain limited. We aimed to quantify the burden of elevated FIB-4 in a primary care setting …
Pharmaceutical Industry Manufacturing Trend For Tablet Dosage Forms And Opportunities For The Future: A Case Study Of Current Practice And Future Developments, Tarang Patel
Discovery Day
INTRODUCTION: Tablet dosage forms remain the most widely utilized oral drug delivery system due to their stability, ease of administration, cost-effectiveness, and scalability. Over recent decades, advancements such as high-speed compression, improved granulation techniques, and regulatory frameworks (bioavailability, validation, and quality assurance) have significantly shaped modern pharmaceutical manufacturing. However, current systems remain largely semi-automated and resource-intensive, highlighting the need for technological transformation.
METHOD: This study presents a case-based evaluation of a contemporary pharmaceutical tablet manufacturing facility. The analysis maps the complete production workflow, including material handling, dispensing, granulation, lubrication, compression, coating, inspection, and packaging. Operational practices were reviewed alongside quality …
Enhancing Research Communication With Visual Tools, Sonya Fogg
Enhancing Research Communication With Visual Tools, Sonya Fogg
Library Class: Lunch & Learn
Understand the role of visual communication in medical research. Distinguish between data visualizations, infographics, and visual abstracts. Identify best practices and some resources and tools for creating effective visuals.
Program (Pdf), Department Of Orthopaedics
Program (Pdf), Department Of Orthopaedics
Dept. of Orthopaedics: Robert D. D’Ambrosia Lectureship & Research Day
Program with abstracts for the 22nd Annual Dept of Orthopaedics Annual Robert D. D’Ambrosia Lectureship & Research Day held June 20, 2026.
‘Latest And Greatest Findings In Aboriginal Cancer Research In Wa ’, Andrew Redfern
‘Latest And Greatest Findings In Aboriginal Cancer Research In Wa ’, Andrew Redfern
Talking Heads Seminar Series
In this talk we will invite the audience to walk with us along the path we have taken over the last 20 years, exploring the reasons why Aboriginal people can experience poorer outcomes when they develop cancer. From there we discuss our search for solutions; cultural, biological and medical, looking at how both improving and personalising our approach to the individual person and the services we build for them may overcome the problems uncovered.
Starting with improved cancer prevention, the talk will move to screening issues and their possible remedies, then on to optimising cure in people with early cancer …
The Readiness Reset: Sleep, Stress, And Pain Management For Tactical Performance, Lauren Fried
The Readiness Reset: Sleep, Stress, And Pain Management For Tactical Performance, Lauren Fried
Tactical & Occupational Performance Conference
Tactical professionals operate in high-demand environments where sleep disruption, chronic stress, and persistent pain are often normalized, but these factors significantly affect readiness, resilience, and long-term performance. This session explores how sleep, stress, and pain interact at the physiological and neurological levels to influence decision-making, recovery, injury risk, and operational effectiveness in first responders and military personnel.
Participants will gain a deeper understanding of how nervous system regulation, circadian rhythms, and pain perception affect both physical and cognitive performance under stress. Drawing on current research and applied human performance principles, this session highlights practical, field-applicable strategies that tactical professionals and …
Mobility And Flexibility For The Tactical Athlete, Nancy Henderson, Haley Worst, Michelle Geter, Mikal Mascarello, Josie Stirling
Mobility And Flexibility For The Tactical Athlete, Nancy Henderson, Haley Worst, Michelle Geter, Mikal Mascarello, Josie Stirling
Tactical & Occupational Performance Conference
Mobility and Flexibility for the Tactical Athlete
Beyond The Expected Window: A Rare Presentation Of Acei-Associated Angioedema Two Decades Into Therapy, Taiwo Ajani, Jose J. Loayza Pintado, Renzo Aller Rojas, Jorge Aboytes Trevino, Michelle Lopez
Beyond The Expected Window: A Rare Presentation Of Acei-Associated Angioedema Two Decades Into Therapy, Taiwo Ajani, Jose J. Loayza Pintado, Renzo Aller Rojas, Jorge Aboytes Trevino, Michelle Lopez
Research Colloquium
Introduction: Angiotensin-converting enzyme inhibitor–induced angioedema (ACEI-AE) is a rare but potentially serious adverse effect of a widely used class of antihypertensives. It typically presents as non-pitting, non-pruritic swelling of the face, lips, tongue, or upper airway, often without associated urticaria. Although most cases occur within the first weeks of treatment, delayed presentations, sometimes after years of stable therapy, have been increasingly recognized. The condition is bradykinin-mediated and often does not respond to standard allergy medications such as antihistamines or corticosteroids.
Case Presentation: A 56-year-old woman with a medical history of hypertension, type 2 diabetes, GERD, and seasonal allergies presented to …
Comparing The Effect Of Oral And Transdermal Estrogen Therapy On Lipid Profile In Postmenopausal Women: A Systematic Review And Meta-Analysis Of Randomized Clinical Trials, Mohamed Doma, Jose J. Loayza Pintado, Aria Atwal, Angelica Lopez Jesus, Farhaan Zahrawi, Ibrahim Saleh, Ahmed El Gammal, Zeyad Maharm, Adham Galal Ramadan, Benito Vlassis, Mustafa Shafeeq Ali, Mohammad Khodr Aljamali, Ralph Pandey, Mounira Mefti, Merhan Badran, Muaaz Aslam, Anuj Subedi, Jaffer Shah, Hani Aiash
Comparing The Effect Of Oral And Transdermal Estrogen Therapy On Lipid Profile In Postmenopausal Women: A Systematic Review And Meta-Analysis Of Randomized Clinical Trials, Mohamed Doma, Jose J. Loayza Pintado, Aria Atwal, Angelica Lopez Jesus, Farhaan Zahrawi, Ibrahim Saleh, Ahmed El Gammal, Zeyad Maharm, Adham Galal Ramadan, Benito Vlassis, Mustafa Shafeeq Ali, Mohammad Khodr Aljamali, Ralph Pandey, Mounira Mefti, Merhan Badran, Muaaz Aslam, Anuj Subedi, Jaffer Shah, Hani Aiash
Research Colloquium
Introduction: Menopause is associated with significant physiological changes, including alterations in lipid profiles. Estrogen therapy plays a crucial role in managing symptoms and preventing long-term complications. This study aims to compare oral and transdermal routes of estrogen therapy among postmenopausal women and assess changes in lipid parameters from baseline.
Methods: Randomized clinical trials comparing oral and transdermal estrogen therapy in postmenopausal women were identified through searches in PubMed, Scopus, Web of Science, and ClinicalTrials.gov. Pooled mean differences (MDs) with 95% confidence intervals (CIs) were calculated using a random-effects model. Statistical analysis was conducted using R version 4.3.2.
Results: Eight randomized …
Cardiovascular Response Patterns To Oral Versus Transdermal Estrogen Therapy In Postmenopausal Women, Mohamed Doma, Jose J. Loayza Pintado, Aria Atwal, Angelica Lopez Jesus, Farhaan Zahrawi, Ibrahim Saleh, Ahmed El Gammal, Zeyad Maharm, Adham Galal Ramadan, Benito Vlassis, Mustafa Shafeeq Ali, Mohammad Khodr Aljamali, Ralph Pandey, Mounira Mefti, Merhan Badran, Muaaz Aslam, Anuj Subedi, Jaffer Shah, Hani Aiash
Cardiovascular Response Patterns To Oral Versus Transdermal Estrogen Therapy In Postmenopausal Women, Mohamed Doma, Jose J. Loayza Pintado, Aria Atwal, Angelica Lopez Jesus, Farhaan Zahrawi, Ibrahim Saleh, Ahmed El Gammal, Zeyad Maharm, Adham Galal Ramadan, Benito Vlassis, Mustafa Shafeeq Ali, Mohammad Khodr Aljamali, Ralph Pandey, Mounira Mefti, Merhan Badran, Muaaz Aslam, Anuj Subedi, Jaffer Shah, Hani Aiash
Research Colloquium
Introduction: The comparative effects of oral versus transdermal estrogen therapy on cardiovascular parameters in postmenopausal women remain incompletely understood. This analysis aimed to evaluate blood pressure and heart rate responses between administration routes.
Methods: A systematic review of randomized trials comparing oral and transdermal estrogen therapy in postmenopausal women was conducted. Primary outcomes included changes in systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate. Random-effects meta-analysis was performed to calculate pooled mean differences (MD) with 95% confidence intervals (CI).
Results: Analysis of 8 randomized trials (N=885) showed no significant differences between oral and transdermal routes in mean …
A Flare Beyond The Gut: Culture-Negative Skin Abscesses In Ulcerative Colitis, Jose J. Loayza Pintado, Mohammad Aqeel, Jorge Aboytes Trevino, Taiwo Ajani, Andres Suarez
A Flare Beyond The Gut: Culture-Negative Skin Abscesses In Ulcerative Colitis, Jose J. Loayza Pintado, Mohammad Aqeel, Jorge Aboytes Trevino, Taiwo Ajani, Andres Suarez
Research Symposium
Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease often complicated by extraintestinal manifestations, with skin involvement seen in up to 15% of patients. Typical lesions include erythema nodosum and pyoderma gangrenosum, but abscess-like cutaneous lesions are almost always assumed to be infectious. Rare case reports describe sterile, culture-negative abscesses arising during UC flares, yet their true prevalence is unknown. We present the case of a young man with UC who developed multiple aseptic skin abscesses in parallel with active proctitis.
Case Presentation: A 19-year-old man with prior Clostridioides difficile infection and subtotal colectomy (rectal preservation) presented with malaise, …
Breaking The Cycle Of Telemetry Overuse: A Resident-Led Quality Improvement Initiative, Jose Donis, Jose J. Loayza Pintado, Luis Salcedo, Renzo Aller, Andres Suarez
Breaking The Cycle Of Telemetry Overuse: A Resident-Led Quality Improvement Initiative, Jose Donis, Jose J. Loayza Pintado, Luis Salcedo, Renzo Aller, Andres Suarez
Research Symposium
Background: Telemetry monitoring is a critical tool in detecting arrhythmias but is frequently overutilized outside of guideline-based indications, contributing to alarm fatigue, unnecessary costs, and resource strain. National guidelines (AHA 2017; BHRS 2020) recommend targeted use, yet adherence remains inconsistent. This quality improvement (QI) project was designed to assess baseline adherence and implement a resident-led intervention to optimize telemetry utilization in a general medicine unit.
Methods: The project was conducted in the 2-West Internal Medicine Unit at Rio Grande Regional Hospital. Residents were integrated into daily telemetry decision-making beginning in November 2024, following structured education with workshops, simulation training, and …
From Skin To Spleen To Brain: Full-Spectrum Embolic Complications In Staphylococcus Aureus Endocarditis, Jose J. Loayza Pintado, Jorge Aboytes Trevino, Julian Galindo, Mohammad Aqeel, John Cauba, Joshua Nwose, Andres Suarez Parraga
From Skin To Spleen To Brain: Full-Spectrum Embolic Complications In Staphylococcus Aureus Endocarditis, Jose J. Loayza Pintado, Jorge Aboytes Trevino, Julian Galindo, Mohammad Aqeel, John Cauba, Joshua Nwose, Andres Suarez Parraga
Research Symposium
Background: Infective endocarditis (IE) results from bacterial adhesion to endocardial tissue and valvular apparatus. While viridans group streptococci and Enterococcus species are associated with subacute disease, Staphylococcus aureus, including methicillin-resistant strains (MRSA), is a leading cause of more acutely destructive presentations. The entry of these pathogens can occur through surgical and dental procedures, intravenous drug use, or less apparent etiology. Classic peripheral stigmata (Osler nodes, Janeway lesions, splinter hemorrhages, Roth spots) are now uncommon but clinically meaningful. Current guidelines emphasize rapid multimodality imaging to detect cerebral and systemic emboli in symptomatic IE. We present a 50-year-old man with S. aureus …
The Bubble, The Blockage, And The Barrier: Weighing Pfo Against Moyamoya In An Stroke Mechanism Diagnostic Challenge In Down Syndrome With Achalasia, Jose J. Loayza Pintado, Adolfo Nava, Jose Donis Castaneda, Taiwo Ajani, Cesar Uribe
The Bubble, The Blockage, And The Barrier: Weighing Pfo Against Moyamoya In An Stroke Mechanism Diagnostic Challenge In Down Syndrome With Achalasia, Jose J. Loayza Pintado, Adolfo Nava, Jose Donis Castaneda, Taiwo Ajani, Cesar Uribe
Research Symposium
Background: Paradoxical embolism through a PFO or small ASD is a common mechanism of stroke in young adults, and randomized trials plus contemporary guidelines support closure in carefully selected 18–60-year-olds to reduce recurrence. Individuals with Down syndrome frequently have congenital heart lesions, raising the pretest probability of shunt-mediated stroke. Yet Down syndrome is also linked to moyamoya arteriopathy, creating diagnostic ambiguity when intracranial narrowing is seen on first-pass imaging. We present a 34-year-old woman with Down syndrome, an acute MCA infarct, and a mildly positive bubble study in whom TEE was deferred for achalasia, illustrating a cardiology-led diagnostic challenge that …
Impact Of Insurance On In-Hospital Mortality And Other Outcomes Among Patients With Acs And Cardiogenic Shock: A Nationwide Analysis From 2022., Renzo Aller, Aura Calderon
Impact Of Insurance On In-Hospital Mortality And Other Outcomes Among Patients With Acs And Cardiogenic Shock: A Nationwide Analysis From 2022., Renzo Aller, Aura Calderon
Research Symposium
Introduction: Insurance coverage may significantly affect access to timely and advanced cardiovascular therapeutic interventions within the United States. Among individuals experiencing acute myocardial infarction (AMI) accompanied by cardiogenic shock (CS), variations based on the primary payer may play a role in subsequent in-hospital outcomes. We conducted a retrospective analysis to determine whether insurance status correlates with in-hospital mortality and other outcomes among patients with AMI and CS, utilizing the NIS database.
Methods: ACS patients in the 2022 NIS were categorized as STEMI or NSTE-ACS using appropriate ICD‐10 codes. Patients with both types of ACS and cardiogenic shock were included in …
The Triple Threat: Hiv, Nonadherence, And Substance Use Driving Premature Coronary Events, Jose J. Loayza Pintado, Taiwo Ajani, Angelica Lopez Jesus, Aura Calderon, Jose Pena
The Triple Threat: Hiv, Nonadherence, And Substance Use Driving Premature Coronary Events, Jose J. Loayza Pintado, Taiwo Ajani, Angelica Lopez Jesus, Aura Calderon, Jose Pena
Research Symposium
Background: People living with HIV (PLWH) experience nearly double the risk of premature atherosclerotic cardiovascular disease and often present with acute coronary syndromes at younger ages [1]. Chronic inflammation, immune activation, and drug–drug interactions between antiretrovirals and antiplatelet agents further contribute to accelerated atherosclerosis and poor outcomes after percutaneous coronary intervention (PCI) [2,3]. Importantly, in-stent restenosis (ISR) remains disproportionately frequent in PLWH despite modern drug-eluting stents, with medication nonadherence compounding risk [4]. We present a young woman with HIV and recurrent myocardial infarction due to rapid ISR, underscoring the impact of inflammation, adherence, and pharmacologic interactions on secondary prevention.
Case …
Survival Outcomes And Tumor Site Distribution By Molecular Subtype In Breast Cancer Patients Under 40, Muhammad Noorani, Shubhank Goyal, Sierra Viduarri, Aura Calderon, Christine Pham, Shweta Singh, Mutaaz Ahmed, Anupam Dhasmana, Swati Dhasmana, Murali Yallapu, Shubash Chauhan, Diane Nguyen, Sidketa Fofana, Sheema Khan
Survival Outcomes And Tumor Site Distribution By Molecular Subtype In Breast Cancer Patients Under 40, Muhammad Noorani, Shubhank Goyal, Sierra Viduarri, Aura Calderon, Christine Pham, Shweta Singh, Mutaaz Ahmed, Anupam Dhasmana, Swati Dhasmana, Murali Yallapu, Shubash Chauhan, Diane Nguyen, Sidketa Fofana, Sheema Khan
Research Symposium
Background: Screening guidelines for breast cancer typically begin at age 40, leaving younger women at risk for delayed detection. The survival outcomes and tumor site patterns by subtype in this younger population remain underexplored. Our analysis leverages comprehensive national data to fill this critical knowledge gap, offering one of the most detailed evaluations to date of molecular subtype distribution, prognostic disparities, and anatomical presentation in women under 40.
Methods: Using the SEER 18 registry, we identified 5,026 female patients diagnosed under age 40 with invasive breast cancer in 2018. This year was selected for the most recent data available on …
Severe Cold Agglutinin Hemolytic Anemia Secondary To Mycoplasma Pneumoniae And Epstein-Barr Virus Co-Infection In An Elderly Patient, Aura Mc Calderon, Jose Loayza, Luis Salcedo, Ivan Mogollon, Asmik Asatrian
Severe Cold Agglutinin Hemolytic Anemia Secondary To Mycoplasma Pneumoniae And Epstein-Barr Virus Co-Infection In An Elderly Patient, Aura Mc Calderon, Jose Loayza, Luis Salcedo, Ivan Mogollon, Asmik Asatrian
Research Symposium
Introduction: Cold autoimmune hemolytic anemia (AIHA) is an uncommon, complement-mediated hemolysis typically driven by IgM autoantibodies; secondary forms are often infection-related. Severe, transfusion-refractory presentations are rare in older adults. We present an elderly patient with Mycoplasma pneumoniae and Epstein–Barr virus co-infection complicated by life-threatening cold agglutinin hemolysis.
Case report: Upon admission, a 79-year-old male patient presented with a one-week history of fatigue, pyrexia, nasal congestion, and dyspnea; examination findings revealed pallor, bibasilar crackles, and mild splenomegaly. Laboratory investigations indicated the presence of severe hemolytic anemia accompanied by compensatory reticulocytosis and thrombocytosis (hemoglobin 5.5 g/dL, hematocrit 17.2%, MCV 100 fL, reticulocytes …
Iptacopan-Responsive Pnh With Pancytopenia: Hematologic Normalization And Dose Adjustment For Transaminitis, Aura Mc Calderon, Jose Loayza, Francisco Arias, Catherine Matos, Bharat Peddinani, Diane Nguyen
Iptacopan-Responsive Pnh With Pancytopenia: Hematologic Normalization And Dose Adjustment For Transaminitis, Aura Mc Calderon, Jose Loayza, Francisco Arias, Catherine Matos, Bharat Peddinani, Diane Nguyen
Research Symposium
Introduction: Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem-cell disorder driven by loss of GPI-anchored complement regulators (CD55, CD59), leading to complement-mediated intravascular hemolysis, cytopenias, and thrombosis. We report a new PNH diagnosis in a young woman with severe pancytopenia who achieved hematologic improvement on oral iptacopan, requiring dose adjustments for mild liver enzyme elevation.
Case Report: On February 27, 2025, a 38-year-old female patient exhibited symptoms of progressive fatigue, dyspnea, and jaundice. Initial laboratory assessments indicated the presence of severe hemolytic anemia accompanied by pancytopenia, hemoglobin level recorded at 4.7 g/dL, white blood cell count at 1.6×10³/µL (absolute …