Medicine and Health Sciences Commons^™

Effects Of Height Increasing Heel Insole On Lower Extremity Joint Mechanics, Youngwook Kim

UNO Student Research and Creative Activity Fair

High-heel shoes alter foot pressure distribution and lower extremity kinetic and kinematics. Unlike general women’s high-heeled shoes, height increasing heel insoles are cushioned, which may contribute to impact absorption. The purpose of this study is to compare the kinetic and kinematics of gaits with and without height increasing heel insoles. Two male subjects performed level walking under two conditions: wearing sports shoes with and without height increasing heel insoles which added additional 5 cm of the heel height (total 6 cm). The vertical ground reaction force (GRF), angle, moment, and power of ankle, knee, and hip during the stance phase …

Creating A Standard In At-Home Pulmonary Exercise Maintenance Programs, Casey Caniglia

UNO Student Research and Creative Activity Fair

Between 12-24 million people in the United States suffer chronic obstructive pulmonary disease (COPD). COPD is linked to reduced physical activity and may be due to effects of the disease on the musculoskeletal system. Pulmonary rehabilitation (PR) clinics offer patients the chance for a better quality of life through exercise programs. However, PR typically lasts 36 sessions and is covered by Medicare. However, any maintenance past the 36 visits requires that costs to be covered by the patient. Cost and access to infrastructure are major barriers to continued supervised maintenance. Lack of confidence and motivation are barriers to at-home fitness …

Session D-2: Don’T Overdose The Patient: A Unit Conversion Literacy Project, Gary M. Baker, David Anim-Addo, Patrick Young

Professional Learning Day

General chemistry for non-science majors is often a prerequisite course for students pursuing degree programs in allied health fields, such as nursing. A core nursing skill is medicine management, which includes correctly calculating drug dosage volumes administered by I.V. or injection. Such calculations are nothing more than general chemistry problems involving concentration units and dilution. Our data show, however, that more than 90% of students lack this skill after taking a traditional general chemistry course. This presentation will focus on documenting this curricular gap and how we, as teachers, can address it.

Effect Of A Passive Exoskeletal Device On Locomotor Adaptive Ability In Healthy Human Subjects, James Nielsen

UNO Student Research and Creative Activity Fair

Background: Functional mobility in stroke survivors is affected by the deterioration in bilateral coordination while walking. A passive exoskeletal device, the Kickstart (Cadence Biomedical, Seattle, WA), that provides assistance during walking may help correct asymmetrical gait patterns by providing different task constraints for each leg during gait training. Methods: 15 healthy young participants walked on a split-belt treadmill where the speed of each belt could be controlled independently. Each participant’s preferred walking speed (PWS), fast walking speed (FWS) and slow walking speed (SWS) was established. Participants then underwent the experimental protocol while either wearing or not wearing the exoskeleton. The …

Animal Assisted Therapy And Reducing Depression In Chronic Hemodialysis Patients, Dawn Delucia

Discovery Day (formerly Post & Beyond)

Chronic dialysis patients are dependent on a hemodialysis machine to cleanse their blood of waste that is normally excreted by healthy functioning kidneys. The average number of hemodialysis treatments required per week are three with an average treatment time being three to four hours per treatment. Discontinuation of hemodialysis will result in death. The only way to eliminate the need for hemodialysis is a kidney transplant (National Kidney Foundation, 2008, 2013). Hemodialysis is not without its inherent risks. Side effects can include but are not limited to: hypotension, cardiovascular complications, cramping from fluid removal, and bleeding (Aguera, Martin-Malo, Alvarez-Lara, Garcia-Montemayor, …

Engagement Of Latino/Hispanic Msm In Hiv Prevention, Natividad Hernandez

UNO Student Research and Creative Activity Fair

Nationally, men who have sex with men (MSM) continue to be significantly affected by HIV compared to other populations. Surveillance data indicates that in Nebraska, between 2011 and 2015, over 55% of new HIV cases were MSM.¹ More specifically, the majority of new HIV cases in the state of Nebraska are reported in Douglas County.² The rate of Hispanic Latino males living with an HIV diagnosis is 2.3 times of white males.³ Similarly, the rate of Hispanic/Latina women living with HIV diagnosis is 3.4 times that white females.³ It is important to identify culturally appropriate messages …

Docking Studies Of Isoform-Selectivity Of Phosphatidylinositol 3-Kinase (Pi3k) Inhibitors, Kaitlin Goettsch

UNO Student Research and Creative Activity Fair

Phosphatidylinositol 3-kinases (PI3Ks) and their related pathways are reputed targets for drug-based anticancer therapies. Mutations in PI3K genes, expression, and pathways are frequent among multiple cancer types. Four isoforms of PI3Ks exist: α, β, γ, & δ and studies have identified several ligands for each isoform which are capable of serving as inhibitory therapeutic compounds. However, the biochemical efficacy of these molecules varies and the isoform selectivity is not well understood. In this study, we applied in silico docking methods and free energy calculation methods to estimate the binding of reported PI3K ligands against 5 PI3K structures: PI3Kα (PBD ID: …

Range Of Motion And Walking Distances In Subjects With Peripheral Artery Disease, Henamari Ybay

UNO Student Research and Creative Activity Fair

Peripheral artery disease (PAD) is caused by blockages in the lower extremity arteries that results in pain during walking known as claudication. Gait variability has emerged as a functional assessment in older and pathological groups1. A healthy gait pattern demonstrates stride-to-stride fluctuations within a certain range of values.2 This study uses standard deviation (SD) and coefficient of variation (CV) to assess the magnitude of variability in the time series. . We compared variability before and after surgery that restores blood flow to the legs of patients with PAD.. Thirty-nine subjects were recruited from the Veteran’s Affairs Medical Center. The setup …

Outcomes Of Early Transition From Intravenous To Oral Antimicrobial Treatment In Pediatric Osteomyelitis, Sofia Rahmanzai

UNO Student Research and Creative Activity Fair

The purpose of this clinical study is to determine the effectiveness of the updated treatment for acute osteomyelitis. This treatment plan consists of early transition from intravenous to oral antimicrobial therapy. The efficaciousness of these therapies were compared with post-discharge outcomes and complication rates. This study will utilize patient records during 2011 to 2016 from the University of Nebraska Medical Center and Children’s Hospital and Medical Center. The study includes patients aged from 1 month to 18 years for acute or unspecified osteomyelitis. Excluded patients are children with chronic osteomyelitis, hospitalization of ten or more days, patients with comorbid conditions …

Construction Of Auxotrophic Strains Of Candida Albicans Clinical Strains, Jenna L. Christiansen

UNO Student Research and Creative Activity Fair

Candida albicans is a yeast commonly found in the gastrointestinal and genitourinary tracts of healthy individuals. Although part of the normal human microbiome, C. albicans can be problematic to certain populations such as individuals with compromised immune systems or those taking broad-spectrum antibiotics. C. albicans is the cause of diaper rash, thrush, vaginal yeast infections, and is a leading cause of systemic infections in hospitals. The focus of C. albicans research has almost entirely been focused on a single strain background, SC5314, found in clade I. This research will contribute to a larger project to delete several marker genes (URA3, …

Meditation As An Intervention For College Students, Ameen Wahba

UNO Student Research and Creative Activity Fair

College students face a variety of stressors and are increasingly susceptible to mental health disorders. Meditation is considered a secular intervention to aid in well-being as well as an aspect of the religious or spiritual experience. In regard to application in daily life, many individuals are unaware of the varieties of meditation available. This work will aim to demystify the practice of meditation in a practical context, specifically focusing its simplicity and lack of cost. Focused Awareness meditation, Open Monitoring Meditation, and Compassion Meditation will be compared and contrasted for their varying benefits in the context of the life of …

The Effect Of Auditory Stimulation On Human Movement Variability And Associated Cortical Involvement, Samuel Maaiah 9051573

UNO Student Research and Creative Activity Fair

The Biomechanics Research Building (BRB) is presently using functional near-infrared spectroscopy (fNIRS) to measure and understand brain activity during human movement and exercise. Compared to other brain activity measuring methods, which require subjects to remain very still during recording, fNIRS allows researchers to study brain activity while subjects perform a range of movement tasks. It is consequently a useful tool for studying movements (e.g. walking) that are not conducive to conventional methods of measuring brain activity. Experiments using fNIRS can vary dramatically in duration depending upon the research question. Some experimental methods contain multiple trials for short time intervals, while …

The Effects Of Walking Speed On Gait Propulsion When Wearing An Ankle-Foot Orthosis, Alli Kalina

UNO Student Research and Creative Activity Fair

Peripheral artery disease (PAD) is a cardiovascular disease that results from blockage of one or more arteries in the lower extremity. Often, patients with PAD have reduced ability to push off with the foot at the end of the gait cycle. When walking, the ankle contributes the majority of the power to propel the body into the next step. An ankle-foot orthosis (AFO) is a device that aids in ankle propulsion by increasing the energy return, thus decreasing the ankle deficit in pathological individuals. The purpose is to investigate the effect of walking speed on ankle propulsion during walking. Subjects …

Modification Of The Ruiz-Moreno Chikungunya Seir Model, Joseph Devlin

UNO Student Research and Creative Activity Fair

The Ruiez-Moreno CHIKV model predicts the outcome of the Chikungunya disease. Chikungunya, a disease similar to the Zika virus, is vector-borne with very little treatment for patients. This experiment looks to find ways to improve the model. The model will still need further improvement, as there is no model that can predict with full certainty. However, a method of modification has been made to expedite the process, the code has been rearranged for easy input and to minimize possibility of unwanted changes, and the control files for comparison have been created. The method to modify the model can be superimposed …

Postpartum Physical Activity And Sleep Levels In Overweight And Normal Weight Mothers, Shane Warehime

UNO Student Research and Creative Activity Fair

Objective: Objectively examine postpartum mothers’ physical activity (PA) and sleep. Compare PA and sleep of overweight/obese and normal weight postpartum mothers. Setting: A mid-sized city in the Midwestern United States. Participants: Twenty-one mothers who had an infant at least three months old. Participants were classified as normal weight (n = 8) or overweight (n = 13). Methods: PA and sleep levels were gathered for four days at three time intervals in the six months following childbirth. Wrist-worn Actigraph accelerometers were used to collect data. Results: All participants increased PA over time, especially from visit two to visit three. When separated …

Levodopa-Induced Morot Behavior Alterations In Dosophila Larvae, James Stanton

UNO Student Research and Creative Activity Fair

Exposing L-Dopa to Drosophila Melanogaster larvae and recording their induced dyskinetic behavior

Cocoa Procyanidin And Β-Cell Proliferation, Whitney Harris, Alonzo Cook Phd, Michael Scott Brashaw Iii, Jeffrey Brown, Kyril Cole, Kody Hasebi, Ysabella Del Rosario, Sara Werner, Bryan Samuel Witt

Biomedical Engineering Western Regional Conference

This presentation explains an experiment that attempts to provide a more thorough understanding on the effect of cocoa procyanidin on β-Cell proliferation in diabetic rats in order to advance the treatment of diabetes.

Structural Mrsa Resistance Through Carbon-Infiltrated Carbon Nanotube Coating Of External Fixator Pins, Jaclyn Larsen, Stephanie Morco, Brian Jensen, Anton Bowden

Biomedical Engineering Western Regional Conference

No abstract provided.

High-Speed Video Capture Of Anterior Cruciate Ligament Tear, Steven L. Cook, Devon T. Smith

Biomedical Engineering Western Regional Conference

High-speed Video Capture of Anterior Cruciate Ligament Tear

Engineering Fret Biosensors For Microrna Presence/Absence Analysis, Nicholas E. Larkey, Sean M. Burrows

Biomedical Engineering Western Regional Conference

No abstract provided.

Bssfp Elliptical Signal Model With Grappa Parallel Imaging, Grayson Tarbox, Joseph Valentine, Meredith Taylor, Neal Bangerter

Biomedical Engineering Western Regional Conference

In magnetic resonance imaging, balanced steady-state free precession acquisition using the elliptical signal model geometrical solution can be combined with a GRAPPA parallel imaging reconstruction that preserves phase information to shorten scan times.

Difference Image Ultra-Short Echo Time T2* Mapping Using A 3d Cones Trajectory, Amin Nazaran, Grayson Tarbox, Randy Hartley, Neal Bangerter

Biomedical Engineering Western Regional Conference

This study introduces a methodology for detecting subtle variations in tissues with very rapid T2* decay through a difference image ultra-short T2* mapping technique using a 3D cones k-space trajectory. The new method is demonstrated in both a normal and surgically repaired Achilles tendon. The resulting UTE images are differenced and T2* values were calculated using a mono-exponential least squares fit on a voxel by voxel basis. The ultrashort T2* maps yield very consistent short T2* values in healthy tendon of 0.3-0.5 ms, while notable variations and elevations of T2* values are observed in surgically repaired tendon.

The Recovery Glove System- A Sensor Driven Glove With Interactive Games For Fine Motor Skill Disabilities, Brian Lee, Oscar Ledezma, Jonathan Rey, Nicholas Alvarado, Deborah Won

Biomedical Engineering Western Regional Conference

Hand mobility is commonly impaired in stroke victims. Treatment for hand impairment range from therapist-guided physical exercises to robotically controlled exoskeletons. However, A more effective treatment which actually restores hand mobility is by encouraging patients to carry out hand movements themselves.We have designed an Arduino based hand therapy device in which the user interacts with a computer graphic interface (CGI) game controlled by a glove was embedded with a force sensing resistor (FSR) at each of the fingertips except for the thumb. The interactive therapy guides the user through exercises and provides live, quantitative information by which the stroke patient …

Heart Pump Modelling: Design Of Pulsatile Flow Phantoms, Olivia Coiado, Kevin Jones, Parker Schibel, Nicolas De Almeida

Biomedical Engineering Western Regional Conference

The purpose of this project is to build a model, which mimics physiological conditions of the human cardiovascular system in order to simulate the parameters of the human heart in vivo. For this project, it was developed a flow phantom with vessel mimicking material, as well as blood-mimicking and tissue-mimicking fluid. Phantoms in general are specifically designed objects involving dedicated biomaterials to simulate special realistic circuits of human beings. To develop the flow phantom, low-priced biomaterials for blood mimicking fluid, tissue mimicking, and vessel mimicking material was researched.

Keywords: Cardiovascular system, heart pump, modelling, pulsatile.

Penetrance Estimates For Incidental Genomic Findings In Acmg-59, James A. Diao

Yale Day of Data

The dropping costs and rising popularity of next-generation sequencing has introduced the possibility of personalizing medical treatments and screening for genetic diseases. Still, the clinical community’s understanding remains incomplete, with limited consensus on the proper interpretation for many genetic variants. Thus, the standard procedure when returning sequencing results has been to report findings only in genes related to the diagnostic indication, and not incidental findings in other genes. To balance the threat of false positives with the medical benefits of true findings, the American College on Medical Genetics and Genomics (ACMG) recommends an exception: that clinical sequencing laboratories seek and …

Need Vs. Supply Analysis Of The New Haven Public Bus System, Stan Mathis

Yale Day of Data

ABSTRACT:

The aim of the study was to assess how well the public transportation system of New Haven County was matched to the public transit need using publicly available geospatial datasets from state and federal sources. Geospatial bus stop data was extracted from public State of Connecticut data sets. Census tract geography was extracted from US Census TIGER files while census tract aggregated household vehicle access data was queried from the American Community Survey data access server. A census tract’s Need was defined as percentage of households reporting access to zero vehicles; its supply was defined as the number of …

Life Of A Child With Hypotonia, Shannon Valedta

School of Human Sciences Research Showcase

The disorder is found in infants, and not many people heard of this disability. People need to be informed about Hypotonia so that it will benefit research to develop a cause and cure to Hypotonia. Also, in our field we are able to educate parents and therapists about what is Hypotonia, and develop techniques for the child to be able to develop properly.

What is Benign Congenital Hypotonia

Benign Congenital Hypotonia, also known as "Floppy Baby Syndrome", is the medical term for low muscle tone.

Sexual Dimorphism In Rat Vascular Function Of Type I And Type Ii Diabetes: Role Of Edrfs, Roshanak Rahimian

Science Seminar Series

Dr. Roshanak Rahimian, professor of physiology and pharmacology in the Thomas J. Long School of Pharmacy and Health Sciences will tell us about her work on understanding the mechanisms underlying the interaction of sex and diabetes in vasculature.

Over the past decade, diabetes and obesity have reached epidemic levels in developed countries, and has become one of the most serious and challenging health problems in the 21st century. Several studies suggest that diabetes affects male and female vascular beds differently. However, the mechanisms underlying the interaction of sex and diabetes in vasculature remain to be investigated. We have shown that …

Tb Screening Guidelines For Transitional Care Unit, Caleb E. Newcomer

Scholars Week

The basis of this research was the formation of new TB screening and risk assessment guidelines on a Transitional Care Unit within a medical center. Current evidence-based research studies helped to guide the recommendations for the policy changes based on their results and findings. The most pertinent policy changes are the treatment offered for patients suspected with HIV, the rigorous use of the Risk Assessment Tool, and BAMT testing for TB.

Personal Protective Equipment Use For Patients With Clostridium Difficile, Mallory L. Compton

Scholars Week

In researching the literature on correct PPE by healthcare staff when a patient has C. diff. I have found that the policy on PPE for patients with C. diff at Baptist Health Paducah is compliant. The theoretical framework used for this research is that of Imogene King. Their policy is evidence based and is also cost effective when it comes to preventing the spread of infection from patient to patient. There is no need for change to this policy at this time because it is supported by evidence in the literature.