Medicine and Health Sciences Commons^™

Emergency Response Time And Fatalities In Rural Areas, Carrie Quinn

Grace Peterson Nursing Research Colloquium

Abstract

More than 90 people die every day in motor vehicle accidents. Rural residents are found to be five times more likely than their urban counterparts to die in a motor vehicle accident and three times more likely to be hospitalized. Many factors contribute to the severity and outcome of an accident; however, emergency medical services response time is one easily modifiable factor that is heavily related to the location of the accident and the patient’s outcome. This purpose of this research was to investigate motor vehicle accidents and emergency response time in a rural setting. The results reveal that …

Clinicians’ Perspectives And Utilization Regarding Harm Reduction In Nursing Practice In Care Of Persons With Addiction: A Literature Review, Audrey Killarney

Grace Peterson Nursing Research Colloquium

Clinicians’ perspectives and utilization regarding harm reduction in nursing practice in care of persons with addiction: A literature review

Audrey Killarney, BS

Prof. Michelle Neuman, MSN, APN, RN

NSG 598: Graduate Research Synthesis

18 August 2017

Introduction

Background & Significance

Harm reduction is a concept best described as the recognition that individuals will engage in unhealthy behaviors, and the goal is to minimize the associated potential harm. (Stockwell, Reist, Macdonald, Benoit, & Jansson, 2010). Classically, it was used an alternative model of care for treating smokers and controlling the spread of HIV and hepatitis B (Henwood, Padgett, & Tiderington, 2014). …

Incidence Of Pediatric Melanoma, Brittany Bendoff

Grace Peterson Nursing Research Colloquium

Background: Over the last 40 years the number of new melanoma cases is not only increasing in adults, but also in children. The rate of pediatric melanoma in males and females ages 1 to 19 has increased by 2% per year since 1973. Risk factors for adult melanomas are well understood, whereas due to the rarity of pediatric melanomas, the risk factors have not been established

Objectives: The purpose of the integrative literature review is to discover if and why the incidence rates of pediatric melanoma are increasing This review will also explore the trends in pediatric melanoma and detection …

Outdoor Physical Activity And Mental Health, Justyna Helinska, Elizabeth Hartman

Grace Peterson Nursing Research Colloquium

Abstract

Background: According to the Center for Disease Control and Prevention (2013), about 25% of US adults have a mental illness. The economic demand that treatment for mental illness involves is extensive. Recent evidence suggests that the outdoor environment that consists of exercise may have an effect on mental health. Present review of literature is unclear how effective this intervention might be if incorporated into an inpatient psychiatric setting.

Objective: Examining the benefits of incorporating outdoor physical activity as an intervention to treat psychiatric disorders.

Method: The literature search for the research topic was found using the databases of: CINAHL …

Coping Strategies Associated With High Quality Of Life In People Diagnosed With Multiple Sclerosis: An Intagrative Literature Review, Alyssa Fitzhugh

Grace Peterson Nursing Research Colloquium

Background: People suffering from Multiple Sclerosis (MS) face many challenges including physical disability, financial strain, and cognitive changes. While the coping mechanisms used to address these stressors can greatly impact one’s quality of life, limited studies are conducted to understand positive coping strategies used by this population.

Objectives: The purpose of this integrative literature review was to examine the types of coping strategies that have a positive impact on quality of life in individuals diagnosed with Multiple Sclerosis.

Methods: An integrative literature review was conducted. The keywords “coping, coping strategies, quality of life, multiple sclerosis, and MS” were used to …

Effective Nursing Interventions For Patients With High Health Anxiety: An Integrative Literature Review, Christina Hetz

Grace Peterson Nursing Research Colloquium

Effective Nursing Interventions For Patients With High Health Anxiety: An Integrative Literature Review

Christina Hetz

Faculty Sponsor: Dr. Young-Me Lee, PhD, RN, Larry Maturin MSN, APN, ACNS-BC, CEN, CCRN

Background: Patients with high health anxiety over seek medical services, resulting unnecessary and possibly invasive tests, consultations, and medication. This behavior ultimately results in iatrogenesis and causes symptoms of high health anxiety to increase.

Aim: The purpose of this integrative literature review was to identify interventions to lessen symptoms of high health anxiety, and the healthcare providers most successful in providing these interventions.

Method: An integrative literature review was conducted using …

The Role Of Implicit Bias On Racial/Ethnic Health Disparities And Its, Anna Kim

Grace Peterson Nursing Research Colloquium

Background: Health disparities are differences in wellness and disease that exist between populations. Health disparities based on race and ethnicity exist in the United States, and implicit bias on the part of the provider may play a part. Objectives: The purpose of this integrative literature review is to describe if implicit bias based on race/ethnicity is found among health care professionals and its impact on health outcomes. Methods: Original studies published after 2006 were found using the CINAHL Complete database. Those that measured implicit bias in health professionals and studied racial/ethnic disparities were included. Results: Six original studies were analyzed, …

Early Life Antibiotic Exposure And Its Association With Overweight/Obesity: An Integrative Review Of The Literature, Margaret Pfaff

Grace Peterson Nursing Research Colloquium

Early Life Antibiotic Exposure and its Association with Overweight/Obesity: An Integrative Review of the Literature

Margaret Pfaff

Faculty Sponsor: Dr. Shannon Simonovich

Background: Prevention of or treatment for obesity could improve quality of life for many people. Infancy may be a critical period during which efforts should be focused to mitigate modifiable factors that may influence the risk for developing obesity.

Objectives: This integrative literature identified factors associated with greater incidence or effects of antibiotic exposure during infancy and examined the connection between early life antibiotic exposure and later in life overweight/obesity.

Method: This analysis followed the Whittemore and Knafl …

Caregivers To Those With Traumatic Brain Injury: Identifying Caregiver Stressors And Effective Interventions, Andrea Vanover

Grace Peterson Nursing Research Colloquium

Abstract

Background: Traumatic Brain Injury is form of acquired brain injury that occurs when a sudden external trauma causes damage to the brain and depending on the severity of the injury, patients will need long-term care from caregivers who provide complete support to the affected. Feelings of stress make caregivers vulnerable to depression, anxiety, and reduce their ability to deal with coping which will further complications of caregiving.

Objective: The purpose of this literature review is to synthesize the research to identify caregiver stressors and clinically proven treatments to reduce caregiver stress in caregivers to those with TBI

Methods: Articles …

Evaluating The Role Of Community Advisory Boards: With Persons Who Inject Drugs In Photovoice Research, Nicole Pallas

Grace Peterson Nursing Research Colloquium

Background: The use of community advisory boards (CABs) is a source of leadership in community-based participatory research (CBPR); however, not all researchers have incorporated CABs, and others have restricted CAB involvement for feasibility purposes. Although there is literature about utilizing CABs in a variety of CBPR studies, less is known about the challenges and successes of working with persons who inject drugs (PWIDs) as CAB members in photovoice methodology, as well as their perceptions throughout the process.

Objectives: The purpose of this qualitative study was to investigate the role CABs play in photovoice research while determining PWIDs’ capacity to fulfill …

Role Of Education In Organ Donation: An Integrative Literature Review, Angelica Dickey

Grace Peterson Nursing Research Colloquium

Role of Education in Organ Donation An Integrative Literature Review

Angelica Dickey

Faculty Sponsor: Angel Butron, RN

Background: Currently in the United States alone, there are over 120,000 individuals waiting for a transplant and on average, 22 individuals will die each day waiting. The current need for organs significantly outweighs the number of organs donated and the education process can help this balance.

Objectives: The purpose of this integrative literature review was to measure the general knowledge of non-healthcare professionals on organ donation and how earlier education can help increase rates of donation.

Method: An integrative literature review was conducted …

Advanced Maternal Age And The Correlation Between Cesarean Birth Rates, Hope Campbell

Grace Peterson Nursing Research Colloquium

According to the Center for Disease Control and Prevention (CDC), the mean age of mothers at the delivery of their first child has increased from 24.9 years to 26.3 years between 2000 and 2014. Miscarriages, financial instability, lack of a partner and more effective contraception may also be associated with the increasing rate of delayed pregnancy. The increasing rate of delayed pregnancy could contribute to the higher rate of cesarean section deliveries in women over the age of 35 which could lead to an increased risk to mother and fetus. The rising cesarean rate is associated with rising costs and …

Nurses Lack Education In Caring For Patients With Down Syndrome, Sarah Coughlin

Grace Peterson Nursing Research Colloquium

Abstract

Individuals with Down Syndrome have a longer life expectancy due to medical advancements made over the past several years. This creates a concern that nurses are not being effectively educated to provide competent care for this population. The purpose of this research was to conduct an integrated literature review which identified nursing knowledge deficits in providing competent care for patients with Down Syndrome. It also examined how nurses can be best educated to provide care for individuals with Down Syndrome to improve their quality of life. Scholarly articles were found searching scholarly databases such as PubMed and CINAHL Complete. …

Factors Contributing To Weight-Gain In Pediatric Psychiatric Patients: An Integrative Literature Review, Holly Ann Douglas Charles

Grace Peterson Nursing Research Colloquium

Obesity and excess weight occur more frequently in the psychiatric patient population. Inappropriate weight gain during in-patient treatment indicates long-term increases in weight. Children are particularly vulnerable to the ill effects of obesity with an increased risk of premature mortality and adult morbidity. Thus, it is imperative to minimize weight gain during psychiatric treatment. The purpose of this review was to identify factors contributing to weight gain in youth psychiatric patients, effective strategies to control modifiable risk factors, and the population that would benefit most from these strategies. An intensive review of literature was conducted. The search utilized multiple databases, …

The Availability & Efficacy Of Non-Pharmacological Interventions For Pain Management For Children With Sickle Cell Disease: A Systematic Review Of The Literature, Uchenna Onyema-Jones

Grace Peterson Nursing Research Colloquium

The Availability & Efficacy of Non-Pharmacological Interventions

For Pain Management for Children with Sickle Cell Disease:

A Systematic Review of the Literature

Uchenna N. Onyema-Jones

Faculty Sponsor: Tamara Poole, MS, APN, FNP-BC

Background: Pain is the leading cause of hospitalizations for many pediatric patients with sickle cell disease and unfortunately it is often sub-optimally managed by healthcare professionals with pharmacological interventions.

Objectives: The purpose of this systematic literature review was to examine the availability and efficacy of non-pharmacological interventions used to manage pain in pediatric patients with sickle cell disease.

Method: A systemic literature review was conducted using the databases …

Best Evidence-Based Best Practices For Helping Women That Are Addicted To Opiates During Pregnancy, Jordan Edwards

Grace Peterson Nursing Research Colloquium

Background: Women of childbearing age that are active opiate users are at high risk of inflicting irreversible damage on not only themselves but onto their unborn children as well. There are limited studies on effective treatment options and education models for pregnant women addicted to opiates. Current practices for helping women that are addicted to opiates do not address the importance of education models for successful cessation of opiate abuse, and defer to treatment options that are used for the general population.

Objectives: The purpose of this integrative literature review was to identify what evidence-based best practices are being used …

Psychological & Psychosocial Deficits Among Pediatric Survivors Of Hematological Neoplasms, Elizabeth Ross

Grace Peterson Nursing Research Colloquium

Background: Pediatric cancer patients are surviving cancer and living long, relatively healthy lives due to advances in pediatric cancer therapeutics. Even with modern medical research and technology, pediatric cancer is still the leading cause of death for children and adolescents in the United States. Based on statistics from the American Cancer Society (ACS), hematological cancers, such as leukemia and lymphoma, are the leading type of non-solid malignancies in children (ACS, 2016). For decades pediatric cancer survival rates have steadily increased with an overall cure rate of over 75%.

While it is great that the survivor rate has and is steadily …

The Influence Of Compassion Satisfaction And Its Effect On The Nurse-Patient Relationship, Brandon Larsen

Grace Peterson Nursing Research Colloquium

No abstract provided.

Intraoperative Blood Pressure And Effect Of Volatile Anesthetic In Brain Dead Organ Donors, Alison Karmanian

Grace Peterson Nursing Research Colloquium

Intraoperative Blood Pressure and Effect of Volatile Anesthetic in Brain Dead Organ Donors

Alison L. Karmanian

Faculty Sponsor: Dr. Pamela Schwartz, CRNA, DNP

Background: There is a large disparity between the number of people waiting for organ transplants and the number of organs available. Optimal hemodynamic management can influence transplant outcomes, therefore evidence-based hemodynamic management should be practiced to maximize scarce donor organs.

Purpose: The purpose of this study was to examine intraoperative blood pressures and administration of volatile anesthetics during brain dead organ donor procurements. Use of volatile anesthetics was examined to determine how use and dose affected the …

Barriers To Advance Directives, Anna Malia Connor Ticknor

Grace Peterson Nursing Research Colloquium

Abstract

Background: Advanced directives (ADs) are legal documents that allows an individual to document their specific wishes for medical care should they be unable to speak for themselves. The use of advanced directives has implications directing the course of end-of-life care affecting both the cost and direction of care. Advance directives can clarify confusion and provide guidance, but their implementation is not clearly defined within the healthcare system. Despite their implications, multiple surveys indicate these documents have limited use within the United States for reasons that are not easily isolated including lack of knowledge of advanced directives and lack of …

Synthesis Of Hydroxybenzylidene-Indolinones, Schiff Bases And N-Substituted Analogs And Their Effects On Bacterial Physiology., Catherine Eliana Cabrera, Neetu Dayal, Moloud Aflaki, Herman Sintim

The Summer Undergraduate Research Fellowship (SURF) Symposium

c-di-AMP is a global stress response regulator involved in some processes of biofilm formation and antibiotic resistance. It has become a candidate target for the development of new antibacterial treatments. Previous studies have shown that hydroxybenzylidene-indolinones can act as c-di-AMP synthase inhibitors. They also act as antibacterial and anti-biofilm inhibitors and re-sensitize resistant bacteria to methicillin and vancomycin. In this project, potent analogs of these compounds, including Schiff bases and N-substituted compounds, have been synthetized. The objective of this work is to explore the effect of these modifications on their biological activity. Base-catalyzed condensation and acid-catalyzed reactions were performed in …

Temporal Resolution Of Cell Death Signaling Events Induced By Cold Atmospheric Plasma And Electroporation In Human Cancer Cells, Danielle M. Krug, Prasoon K. Diwakar, Ahmed Hassanein

The Summer Undergraduate Research Fellowship (SURF) Symposium

Cancer treatment resistance and their invasive and expensive nature is propelling research towards developing alternate approaches to eradicate cancer in patients. Non-thermal, i.e., cold atmospheric plasma (CAP) and electroporation (EP) applied to the surface of cancerous tissue are new methods that are minimally invasive, safe, and selective. These approaches, both independently and synergistically, have been shown to deplete cancer cell populations, but the signaling mechanisms of death and their timelines of action are still widely unknown. To better understand the timeframe of signaling events occurring upon treatment, human cancer cell lines were treated with CAP, EP, and combined CAP with …

Effects Of Stroma On Er+ Breast Cancer Cell Metastasis, Shipeng Xu, Luis Solorio, Sarah Calve

The Summer Undergraduate Research Fellowship (SURF) Symposium

Breast cancer is one of the most wide-spread diseases among women in America. If the cancer is local, it is easily controlled by surgical resection. However, if the cancer cells metastasize, patient survival is significantly reduced. 70% of breast cancers can be targeted through estrogen receptors (ER) on the membrane, with compounds such as tamoxifen. However, tamoxifen shows unreliable outcomes on different patients and it is believed that the ineffectiveness of tamoxifen is related to the epithetical-mesenchymal transition (EMT) of cancer cells. To address this problem, we are designing a system that stimulates metastasis activation with the aim of incorporating …

Three-Dimensional Microfluidic Tumor Vascular Model For Investigating Breast Cancer Metastasis, Anastasiia Vasiukhina, Brian H. Jun, Luis Solorio, Pavlos P. Vlachos

The Summer Undergraduate Research Fellowship (SURF) Symposium

Metastasis is one of the primary reasons for the high mortality rates in female patients diagnosed with breast cancer. It involves the migration of cancer cells into the circulatory system allowing for the dissemination of cancer cells in distal tissues. Understanding the major processes that occur in cells and tissues during metastasis can help improve currently existing therapeutic methods. In order to understand such mechanisms, developing physiologically relevant tissue models is crucial. Advancements in microfluidics have led to the fabrication of 3D culture models with shear stress gradients and flow control that can recapitulate aspects of the tumor microenvironment in …

Finding Human Proteins That Bind To A Lassa Virus Protein, Maria Alejandra Pardo Ruge, Veronica J. Heintz, Douglas J. Lacount

The Summer Undergraduate Research Fellowship (SURF) Symposium

Viral hemorrhagic fevers are severe illnesses caused by many different viruses. Lassa Virus is one of these important pathogens in Western Africa, causing hemorrhagic fever and eventually death without early medical treatment. There is no vaccine and there is little information on host-pathogen interactions. Therefore, the interaction between viral proteins and host targets is useful to understand Lassa virus’s lifecycle and pathology, and to develop ways to prevent infection. In this project, we study the nucleoprotein of Lassa virus (NP), which has been reported to have anti-interferon (IFN) activity through elimination of double stranded RNA (dsRNA). These features could be …

Development Of Self-Assembling Nanoparticles For Drug Delivery Applications, Young Chan Kim, Craig Sweet, Helen Margaret Flynn, David H. Thompson

The Summer Undergraduate Research Fellowship (SURF) Symposium

Bladder cancer is the ninth most common cancer in the world, and occurs in nearly four percent of all men. Although many cases are diagnosed as early stage cancer and the tumor can be removed by surgery, reoccurrence rates are high making treatment difficult and thus one of the most expensive cancers. To address this problem, drugs are injected intravesically after tumor removal to kill any residual cancer that may cause reoccurrence. While this was a significant improvement over surgery alone, high toxicity along with short residence times in the bladder limited its effectiveness. To combat these shortcomings, we will …

Fret Biosensors: Engineering Fluorescent Proteins As Biological Tools For Studying Parkinson’S Disease, Nathan J. Leroy, Jacob R. Norley, Saranya Radhakrishnan, Mathew Tantama

The Summer Undergraduate Research Fellowship (SURF) Symposium

Parkinson’s Disease (PD) is a common neurodegenerative disease with over 200,000 new cases each year. In general, the cause of the disease is unknown, but oxidative stress inside of neurons has been associated with the disease’s pathology for some time. Currently, techniques to study the onset of PD inside of neurons are limited. This makes treatments and causes difficult to discover. One solution to this has been fluorescent protein biosensors. In short, these proteins can be engineered to glow when a certain state is achieved inside a cell. The present research discusses the engineering of a genetically-encoded fluorescent protein (FP) …

Determining The Structure Of Phospholipase C Epsilon, Hannah O'Neill, Monita Sieng, Elisabeth Garland-Kuntz, Angeline Lyon

The Summer Undergraduate Research Fellowship (SURF) Symposium

The phospholipase C (PLC) epsilon subfamily of PLC enzymes are found at highest concentration within the cardiovascular system. Improper functioning of the enzyme, whether due to overstimulation or changes in expression, has far-reaching effects within the human body Stunted heart valve development and cardiac hypertrophy and are two such examples. The mechanisms by which PLC epsilon activity is regulated in these processes remain unknown, as does the physical structure of the enzyme. In this study, we seek to determine the structure of a PLC epsilon fragment that retains enzymatic activity and is amenable to crystallization. Mutagenesis of PLC epsilon cDNA …

Computational Drug Design: A Multitargeted Approach In Bladder Cancer, Travis C. Lantz, Joydeb Majumder, Gaurav Chopra

The Summer Undergraduate Research Fellowship (SURF) Symposium

Cancer is a complex, robust disease with multiple redundant disease pathways which lead to tumor development, growth, and eventually even death. Despite known redundancies, cancer therapeutics continue to be developed against a single protein target. Initial disease regression occurs followed by relapse in a drug resistant disease state. In response, combinational drug clinical trial targeting multiple pathways began, and have failed due to increased toxicity caused by adverse drug interactions. Development of a single drug that differentially targets multiple disease pathways will result in a more potent therapeutic while inducing minimal toxicity. This was done computationally through in-lab software packages, …

19th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.