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Full-Text Articles in Medicine and Health Sciences

A Glimmer Of Hope? Assessing Hope As A Moderator Of The Relationship Between Parenting And Adolescent Depressive Symptoms, Lisa D. Bishop Jul 2014

A Glimmer Of Hope? Assessing Hope As A Moderator Of The Relationship Between Parenting And Adolescent Depressive Symptoms, Lisa D. Bishop

Theses and Dissertations

Prior research has established that a portion of depressive symptoms in adolescents is predicted by parenting behaviors. The purpose of this study was to identify the moderating role of hope on the relationship between two parenting variables (warmth and psychological control) and adolescent depressive symptoms. Participants included 459 adolescents ages 13 to 14 years and their families from waves 3 and 4 of the Flourishing Families Project. Path analysis was utilized to answer the proposed hypotheses and research questions. Multiple group analysis was utilized to determine if results were different for boys and girls. Significant results indicated that in low-hope …


Partner Attachment And The Parental Alliance, Ashley B. Bell Jul 2014

Partner Attachment And The Parental Alliance, Ashley B. Bell

Theses and Dissertations

Previous research has demonstrated that cooperation and support between parents, called the parental alliance, is an important predictor of parent and child well-being. Consequently, it is important to understand what factors promote the formation of a strong parental alliance. Because of research on the impact of attachment security on individuals' abilities to depend and rely on others and to appropriately manage conflict, partner attachment is a potential predictor of the parental alliance, with insecure attachment negatively weakening the parental alliance. This study analyzed data from 321 couples to examine the relationship between partner attachment and the parental alliance. Using the …


Treatment Outcomes For Mood Disorders With Concurrent Partner Relational Distress: A Comparison By Treatment Modality And Profession, Holly Pack Jul 2014

Treatment Outcomes For Mood Disorders With Concurrent Partner Relational Distress: A Comparison By Treatment Modality And Profession, Holly Pack

Theses and Dissertations

Mood disorders are often linked with concurrent partner relational distress. The present study compared the cost effectiveness of treating mood disorder alone versus when the condition is comorbid with partner relational distress. Cigna, a leading health insurance management company in the US, provided outpatient data. Participants included patients with solely a mood disorder diagnosis (n = 72,712) and those with both a mood disorder and a comorbid partner relational distress diagnosis (n = 113, including 69 females and 44 males). These participants were treated in outpatient settings throughout the US. These numbers are surprisingly low considering the extensive literature showing …


Commitment, Forgiveness, And Relationship Self-Regulation: An Actor-Partner Interdependence Model, Heather Michele Smith Jul 2014

Commitment, Forgiveness, And Relationship Self-Regulation: An Actor-Partner Interdependence Model, Heather Michele Smith

Theses and Dissertations

Relationship self-regulation (RSR) refers to the “work”, or effort and strategies, that partners exert over time to maintain the health of their romantic relationships. Most research focuses on self-reports of RSR, however, several studies suggest that partner perceptions are more influential in relationship appraisal. In addition, most RSR research has focused not on partners' attitudes and virtues like commitment, but instead on personality traits, emotional health, and communication skills. In this study, we examine the relationship between partners' levels of commitment and forgiveness within their relationships, and how they perceive their partner's use of RSR behaviors. Using paired data from …


The Impact Of Parentification On Depression Moderated By Self-Care: A Multiple Group Analysis By Gender For South Korea And The U.S., Sunnie Giles Jun 2014

The Impact Of Parentification On Depression Moderated By Self-Care: A Multiple Group Analysis By Gender For South Korea And The U.S., Sunnie Giles

Theses and Dissertations

Parentification, the process of role reversal between parent and child, has long-term deleterious consequences. Using 500 men and 501 women, ranging from 18 years to 55 years old, residing in Korea and the U.S., this study examined the relationship of parentification experienced during childhood and depression in adulthood. The moderating impact of gender and self-care was examined in both the Korean and U.S. samples. Multiple-group analysis showed that the relationship between parentification and depression was statistically significant in all groups (U.S., Korean, male, and female), and self-care was negatively linked to depression. However, self-care did not moderate the relationship between …


Stable Conflict Resolution Styles And Commitment: Their Roles In Marital Relationship Self-Regulation, Rebecca Suzanne Boyd Jun 2014

Stable Conflict Resolution Styles And Commitment: Their Roles In Marital Relationship Self-Regulation, Rebecca Suzanne Boyd

Theses and Dissertations

Gottman's (1994a) three stable conflict resolution styles (CRSs), validating, volatile, and avoidant, are different on several dimensions, yet all are predictors of good marital satisfaction. Despite the CRSs equality in marital satisfaction and stability research, teaching couples a validating style is often explicitly more preferential in therapeutic settings. Relationship self-regulation (RSR), described as relationship “work”, is also a strong predictor of relationship satisfaction. Identifying the CRS environment in a relationship that most contributes to the practice of RSR can inform clinical and couple relationship education interventions. Based on its success in improving marital satisfaction in therapeutic settings, a validating CRS …


Money Management For The Severe And Persistently Mentally Ill, Simone Kurtz-Dougherty Jun 2014

Money Management For The Severe And Persistently Mentally Ill, Simone Kurtz-Dougherty

Theses and Dissertations

Five men diagnosed with Severe and Persistent Mental Illness (SPMI) were recruited from a partial care program to participate in a study on the efficacy of teaching money management skills. The participants were also assessed on perceived stress, financial strain, and symptomology. The men were randomly assigned to either an experimental group or a waitlist control group; both groups received an intervention for money management consisting of a workshop on budgeting and weekly coaching based on expenses. Participants in the experimental group received the money management class immediately after a pretest baseline was established and the wait-list control group received …


The Efficacy Of Social Communication Intervention On Teacher Report Of Sociability For Children With Language Impairment, Julianne Grover Smith Guerra Jun 2014

The Efficacy Of Social Communication Intervention On Teacher Report Of Sociability For Children With Language Impairment, Julianne Grover Smith Guerra

Theses and Dissertations

Recent research indicates that many children with Language Impairment (LI) have difficulty with social communication skills. This study assessed the impact of a social communication intervention on teacher perceptions of social withdrawal in children who received the treatment. The intervention targeted emotion understanding using the presentation of children's stories, facial picture cards, and journaling. Teacher perception was measured using the three withdrawal subscales of the Teacher Behavior Rating Scale (TBRS): Solitary-Active withdrawal, Solitary-Passive withdrawal, and Reticence. Following treatment all five participants received lower ratings of withdrawn behavior on some of the subscales. Only one participant received a rating indicting increased …


Oncology Nurses' Suggestions For Improving Obstacles In End-Of-Life Care, Rosanne Johnson Oliver Jun 2014

Oncology Nurses' Suggestions For Improving Obstacles In End-Of-Life Care, Rosanne Johnson Oliver

Theses and Dissertations

The purpose of this paper was to determine the most important changes needed to improve the quality of end-of-life (EOL) care to terminal cancer patients as perceived by experienced oncology nurses. The study was designed as a cross-sectional survey, sampling 1,000 Oncology Nursing Society members from the United States with experience caring for inpatient cancer patients, who could read English, and had experience in EOL care. Eligible nurses responded to an open-ended item sent to them as part of a mailed questionnaire. Nurses were asked to respond to the following question: “If you had the ability to change just one …


Children's Adaptation To Electropalatography: Evidence From Acoustic Analysis Of /T/ And /K/, Kara Brianne Knapp Jun 2014

Children's Adaptation To Electropalatography: Evidence From Acoustic Analysis Of /T/ And /K/, Kara Brianne Knapp

Theses and Dissertations

Electropalatography (EPG) is a computer-based device that uses a fitted pseudopalate (similar to an orthodontic retainer) with embedded electrodes to track tongue-to-palate contact during speech for the purposes of providing treatment for a variety of communication disorders. This study evaluated six elementary school-aged children's ability to adapt their speech to the presence of the pseudopalate in their mouth. The participants' adaptation for the consonants /t/ and /k/ was examined over eight time intervals throughout a two and half hour time period. Adaptation was evaluated by measuring the duration, spectral mean, spectral variance, and relative intensity of the target sounds. The …


Vaccination Status And Attitudes Of Urban School Employees In Utah, Kim Estella Thompson Jun 2014

Vaccination Status And Attitudes Of Urban School Employees In Utah, Kim Estella Thompson

Theses and Dissertations

Individuals who work with children are at risk for exposure to vaccine-preventable diseases. School settings can quickly become outbreak centers for communicable infection since school employees are in direct contact with children in confined areas for many hours each day. Therefore, it is important for school employees to be fully vaccinated. There are many reasons school employees may be inadequately vaccinated. One common myth is that adults believe vaccines are only for children. Another reason for inadequate vaccination rates among school employees is that many adults believe vaccinations received during childhood are still effective. Healthcare providers (HCPs) constitute the first …


A Model Of Grammatical Category Acquisition Using Adaptation And Selection, Sarah Zitting Cluff Jun 2014

A Model Of Grammatical Category Acquisition Using Adaptation And Selection, Sarah Zitting Cluff

Theses and Dissertations

By the later preschool years, most children have a knowledge of the grammatical categories of their native language and are capable of expanding this knowledge to novel words. To model this accomplishment, researchers have created a variety of explicit, testable models or algorithms. These have had partial but promising success in extracting grammatical word categories from transcriptions of caregiver input to young children. Additional insight into children's learning of the grammatical categories of words might be gained from evolutionary computing algorithms, which apply principles of evolutionary biology such as variation, adaptive change, self-regulation, and inheritance to computational models. The current …


Speech Adaptation To Electropalatography In Children's Productions Of /S/ And /ʃ/, Marissa Celaya Jun 2014

Speech Adaptation To Electropalatography In Children's Productions Of /S/ And /ʃ/, Marissa Celaya

Theses and Dissertations

Previous research has investigated adults' ability to adapt their speech when a electropalatographic (EPG) pseudopalate is placed in the oral cavity; however, less is known about how younger speakers who are continuing to develop their motor speech abilities might adapt their speech to the presence of the device. This study examined the effect of an EPG pseudopalate on elementary school-aged children's ability to produce the fricatives /s/ and /ƒ/. Audio recordings of six children were collected at eight time intervals including before placement of the pseudopalate, at 30-minute increments for two hours with the pseudopalate in place, immediately following removal …


A Comparison Of Contemporary Filial Piety In Rural And Non-Rural China And Taiwan, Li Ping Su Jun 2014

A Comparison Of Contemporary Filial Piety In Rural And Non-Rural China And Taiwan, Li Ping Su

Theses and Dissertations

There is evidence that industrialization and urbanization has led to an increase of immigration to urban areas for employment and has led to a change of family structure and connection between parents and adult children in Chinese societies. However, little research has compared different Chinese societies, as well as rural and non-rural regions. This study compared the adult children’s current level of filial piety, between non-rural and rural regions, and between males and females using data from an international study of countries in East Asia. Overall, China reported higher level of filial piety as compared to Taiwan. Moreover, for the …


Distress In Women With Ovarian Cancer, Judith Dellaripa May 2014

Distress In Women With Ovarian Cancer, Judith Dellaripa

Theses and Dissertations

Clinicians and researchers know that women experience distress related to the diagnosis of and treatment for ovarian cancer. A review of the literature revealed that while there is interest in the topic, distress is inconsistently defined and measured. Women have been reported to have a variety of distress experiences including the challenges of late diagnosis and the treatment regimen, communication difficulties with healthcare providers, and concern about the effect of their diagnosis on their loved ones. Without information directly from women, assumptions predominate about what the experience is like and what they would find helpful from support persons. Women’s perceptions …


Mandibular Incisor Proclination Variability During Class Ii Correction, James Redford May 2014

Mandibular Incisor Proclination Variability During Class Ii Correction, James Redford

Theses and Dissertations

Background: Lower incisor proclination has been shown to increase during Class II correction with appliances such as the Forsus. This lower incisor flaring shows great variability among patients. The purpose of this study was to evaluate the effects of Class II severity, mandibular growth, and occlusal plane rotation on lower incisor flaring in patients treated with the Forsus appliance. Materials and Methods: 121 records of Class II patients treated with the Forsus appliance were analyzed retrospectively. Cephalograms were traced at three time points. ANOVA was used to compare changes in cephalometric measurements over time. Pearson’s correlation was used to test …


The Reporting Of Supplement Use By Dental Patients On Their Medical History Questionnaire, Sarmad Bakuri May 2014

The Reporting Of Supplement Use By Dental Patients On Their Medical History Questionnaire, Sarmad Bakuri

Theses and Dissertations

The Reporting of Supplement Use by Dental Patients on Their Medical History Questionnaire Objectives: The goals of the study were three fold. Estimate the prevalence of supplement use by dental patients. Determine if the design of a medical history form influences the prevalence of supplement use reported. Determine whether or not patients are aware of supplement side effects and interactions with medications. Methods: Patients were randomly allocated to either a standard medical history form or the same form with additional questions about supplement use. After completing the initial forms, a survey containing questions about supplements was filled out by both …


The Fluoride Recharging Capability Of An Orthodontic Primer: An In Vitro Study, Samuel Allen May 2014

The Fluoride Recharging Capability Of An Orthodontic Primer: An In Vitro Study, Samuel Allen

Theses and Dissertations

Objective: The purpose of this study was to determine the fluoride recharging capability of Opal Seal, a fluoride releasing orthodontic primer, as compared to Transbond XT, the control. Material and Methods: 1mm x 5mm disks of Opal Seal and Transbond were prepared according to the respective manufacturer’s instructions. Initially, the samples were stored in deionized water (DI) for 8 weeks. The samples were then randomly divided into one of two groups: Over-the-counter (OTC) fluoride mouthwash and prescription strength (PS) fluoride mouthwash. The OTC group samples were immersed in 5mL of 0.0219% sodium fluoride containing mouthwash for one minute every day …


A School-Based Intervention’S Impact On Children’S Knowledge And Self-Efficacy Related To Physical Activity And Nutrition: A Pilot Study, Katherine Turley Jenkins May 2014

A School-Based Intervention’S Impact On Children’S Knowledge And Self-Efficacy Related To Physical Activity And Nutrition: A Pilot Study, Katherine Turley Jenkins

Theses and Dissertations

Childhood obesity has become epidemic in the United States. One of the best places to combat this problem is within the school system. The purpose of this study was to examine changes in exercise self-efficacy, science interest, and science knowledge of children who participated in a school-based anatomy and healthy lifestyle intervention called Anatomy Academy. In this pilot study, 212 study participants were recruited from 5th and 6th grade children enrolled in one of three charter schools who participated in our 7-week intervention, Anatomy Academy. Children completed four questionnaires pre and post intervention: (1) a science knowledge questionnaire, (2) a …


The Impact Of The Ohana Mana Challenge On Native Hawaiian And Pacific Islander Children, Kristin Kay Van Tassell May 2014

The Impact Of The Ohana Mana Challenge On Native Hawaiian And Pacific Islander Children, Kristin Kay Van Tassell

Theses and Dissertations

In this four-week, family-focused pilot intervention study, researchers studied the impact of culturally relevant nutrition and activity sessions on eleven children from eight Native Hawaiian and Pacific Islander (NHPI) families. Mixed methods were used in analysis. In their favorite meal drawings, children included more fruits and vegetables at week four than week one, which was consistent with their self-reported intake of healthy foods that were new to them. From week one to four, mean total scores increased on the nutrition and exercise knowledge exercise questionnaire and the physical activity self-efficacy tool; however, the mean total score decreased on healthy diet …


The Role Of Cytoprotective And Non-Protective Autophagy In Radiation Sensitivity In Breast Tumor Cells, Jade Le May 2014

The Role Of Cytoprotective And Non-Protective Autophagy In Radiation Sensitivity In Breast Tumor Cells, Jade Le

Theses and Dissertations

In general, ionizing radiation promotes cytoprotective autophagy in a majority of breast tumor cells. Previous studies from our laboratory indicated that radiation (5x2 Gy) induces cytoprotective autophagy in MCF-7 cells. In the current work, inhibition of autophagy by silencing of Beclin-1 in MCF-7 cells resulted in an increase in sensitivity to radiation based both on cell number and clonogenic survival; however, there was no increase in apoptosis and the basis for this sensitization is currently under investigation. Unexpectedly, enhancement of autophagy by silencing of Bcl-2 also led to an increase in sensitivity to radiation, possibly through the conversion of cytoprotective …


Relationship Of Mitochondrial Enzymes To Fatigue Intensity And Health-Related Quality Of Life In Men With Prostate Cancer Receiving External Beam Radiation Therapy, Kristin Filler May 2014

Relationship Of Mitochondrial Enzymes To Fatigue Intensity And Health-Related Quality Of Life In Men With Prostate Cancer Receiving External Beam Radiation Therapy, Kristin Filler

Theses and Dissertations

Introduction: Cancer-related fatigue is often described by patients as a lack of energy, mental or physical tiredness, diminished endurance, and prolonged recovery after activity. Etiologic mechanisms underlying CRF are not well understood. Methods: A literature review was conducted to examine studies that had investigated the association of mitochondrial dysfunction with fatigue. The major conclusion from this review was that alterations in energy metabolism may contribute to fatigue. Therefore, the dissertation study focused on laboratory techniques for measuring mitochondrial oxidative phosphorylation enzymes (complexes I-V) and a mitochondrial-specific oxidative stress marker (superoxide dismutase 2 [SOD2]). The primary aim of the dissertation research …


Role Of Membrane Fusion Protein Ykt6 In Regulating Epithelial Cell-Cell And Cell-Matrix Adhesions., Supriya Joshi May 2014

Role Of Membrane Fusion Protein Ykt6 In Regulating Epithelial Cell-Cell And Cell-Matrix Adhesions., Supriya Joshi

Theses and Dissertations

Intercellular junctions and cell-matrix adhesions play important roles in the maintenance of epithelial integrity. Assembly and remodeling of the plasma membrane complexes are regulated by membrane trafficking and fusion. This thesis is aimed to elucidate the roles of an important membrane fusion protein, Ykt6, in the regulation of epithelial cell adhesion and migration. For the first time, we show that Ykt6 is essential for assembly of adherens junctions and tight junctions in human prostate epithelial cells. We also observed that Ykt6 negatively regulates both collective epithelial cell migration and cell invasion into Matrigel. The effects of YKT6 on epithelial junctions …


Factors Contributing To Infant Feeding Practices With Latina Mothers, Diana Cartagena May 2014

Factors Contributing To Infant Feeding Practices With Latina Mothers, Diana Cartagena

Theses and Dissertations

Background: An estimated 9.7% of U.S. infants and toddlers are considered overweight. Hispanic infants persistently show higher prevalence rates for being overweight compared to black and white infants. Little is known about factors promoting excessive infant weight gain in Latinos. Purpose: Primary aim of this study was to describe multidimensional factors and maternal feeding practices that may correlate with infant overfeeding in Latina mothers. A secondary aim was to determine whether there was an association between these factors and infant weight gain. Subjects: Sixty-two low-income immigrant Latina mothers and their infants ages 4-12 months receiving assistance through the Special Supplemental …


Structural Alterations To The Axon Initial Segment Following Diffuse Axonal Injury As A Consequence Of Age, William Behl May 2014

Structural Alterations To The Axon Initial Segment Following Diffuse Axonal Injury As A Consequence Of Age, William Behl

Theses and Dissertations

An epidemiological shift towards the elderly population has occurred in traumatic brain injury (TBI). Age is believed to be one of the strongest prognostic indicators following TBI. Diffuse axonal injury (DAI), a prevalent feature of TBI, is believed to be the primary cause for much of the morbidity and mortality associated with TBI. The pathobiology associated with DAI is believed to occur in response to the primary injury in a progressive, secondary fashion. Though the injury mechanisms behind DAI have been shown to occur at numerous sites along the axon, recent work suggests that the axon initial segment (AIS) may …


Investigations Of Novel Mechanisms Of Action For Anti-Bacterial And Anti-Cancer Agent Development, Jenson Verghese May 2014

Investigations Of Novel Mechanisms Of Action For Anti-Bacterial And Anti-Cancer Agent Development, Jenson Verghese

Theses and Dissertations

The development of drugs and therapeutic agents for combating infections and human malignancies continues to be a forefront area in both academic and industrial research. This is driven by the rapid emergence of multi-drug resistant bacterial strains and accumulating mutations in cancer targets that is quickly rendering our current arsenal of drugs ineffective for these therapies. Unless new drugs with novel mechanisms of action are identified and developed at a faster pace, we face a losing battle in managing these diseases. The first part of this work concerns with the natural product Simocyclinone D8 (SD8). Simocyclinone D8 is an angucyclinone …


A Retrospective Study Of Operating Room Utilization And Efficiency In A Pediatric Dental Residency Program, Brian Burke Apr 2014

A Retrospective Study Of Operating Room Utilization And Efficiency In A Pediatric Dental Residency Program, Brian Burke

Theses and Dissertations

Purpose: The purpose was to assess and understand operating room (OR) utilization and efficiency in a pediatric dental residency program. Methods: A retrospective study was performed using chart extraction from 778 patients completed by both pediatric dentistry faculty (n=7) and residents (n=17) in an ambulatory care setting over a 32 month period (between July 2010 and March 2013). Patterns in OR usage time were determined by documenting various timing metrics (start and stop times for anesthesia, start and stop times for the dental procedure, times for throat pack in and out), noting patient information (age and ASA patient classification status), …


Prevalence And Distribution Of Periapical Lesions Submitted For Histopathologic Analysis By Endodontists, Gerhard Claire Siegel Apr 2014

Prevalence And Distribution Of Periapical Lesions Submitted For Histopathologic Analysis By Endodontists, Gerhard Claire Siegel

Theses and Dissertations

The current understanding of the distribution and frequency of periapical pathoses include biopsies submitted by all specialists and general dentists. As a result, they do not accurately reflect the distribution seen by endodontists. This retrospective chart review aims to determine the prevalence of periapical pathoses and associated demographics from biopsies submitted by endodontists over 30 years. All biopsy reports submitted to the Virginia Commonwealth University Oral Pathology Diagnostic Service from January 1, 1983 to December 31, 2012 were reviewed. Only reports submitted by verified endodontists and those with a periapical location were included. The following data was recorded from each …


Clinical And Radiographic Evaluation Of Mta Pulpotomies: A Retrospective Study, Claudia Colorado Apr 2014

Clinical And Radiographic Evaluation Of Mta Pulpotomies: A Retrospective Study, Claudia Colorado

Theses and Dissertations

Vital pulp therapy is the group of procedures indicated to maintain pulp vitality allowing for continued root development and apical closure in the presence of pulp exposure due to caries or trauma. Complete maturation results in stronger tooth structure that is more able to withstand occlusal forces. Historically, calcium hydroxide (Ca(OH)2) was the material of choice for a vital pulpotomy. Recently mineral trioxide aggregate (MTA) has been used as a pulp sealing material because of its biocompatibility and its ability to induce hard tissue barrier formation. The purpose of this retrospective study was to evaluate the clinical and radiographic outcome …


The Roles Of Krüppel-Like Transcription Factors Klf1 And Klf2 In Mouse Embryonic And Human Fetal Erythropoiesis, Divya Vinjamur Apr 2014

The Roles Of Krüppel-Like Transcription Factors Klf1 And Klf2 In Mouse Embryonic And Human Fetal Erythropoiesis, Divya Vinjamur

Theses and Dissertations

Hemoglobinopathies are some of the most common monogenic disorders in the world, affecting millions of people and representing a growing burden on health systems worldwide. Although the pathophysiology of sickle cell anemia and beta-thalassemia, two of the most common hemoglobinopathies, have been the focus of much research over the last century, patients affected by these diseases still lack a widely applicable and easily available cure. Sickle cell anemia and beta-thalassemia are caused by defects in the structure and production of the beta-globin chains that, along with the alpha-globin chains make up the heterotetrameric hemoglobin molecule. Studies geared towards re-expression of …