Medicine and Health Sciences Commons^™

The Influence Of Adaptive Challenge On Engagement Of Multidisciplinary Staff In Standardising Aseptic Technique In An Emergency Department: A Qualitative Study, Amanda Towell-Barnard, Susan Slatyer, Helen Cadwallader, Michelle Harvey, Susan Davis

Research outputs 2014 to 2021

Aims and objectives: To explore the challenge of engaging multidisciplinary staff in standardising aseptic technique (AT) in an emergency department (ED) in an Australian tertiary hospital, and to better understand the enablers and barriers to implementing practice change within this setting.

Background: Healthcare‐associated infections are the most common complication for patients in acute care. A clinical practice framework developed in the United Kingdom (UK) standardised AT practice to reduce potential infection risk. One Australian tertiary hospital drew upon this framework to similarly improve clinical practice. It was understood that standardising practice would require some practitioners only to revisit and demonstrate …

Association Of Suboptimal Health Status With Intestinal Microbiota In Chinese Youths, Qi Sun, Xizhu Xu, Jie Zhang, Ming Sun, Qiuyue Tian, Qihuan Li, Weijie Cao, Xiaoyu Zhang, Hao Wang, Jiaonan Liu, Jinxia Zhang, Xiaoni Meng, Lijuan Wu, Manshu Song, Hongqi Liu, Wei Wang, Youxin Wang

Research outputs 2014 to 2021

Suboptimal health status (SHS), a physical state between health and disease, is a subclinical and reversible stage of chronic disease. Previous studies have shown alterations in the intestinal microbiota in patients with some chronic diseases. This study aimed to investigate the association between SHS and intestinal microbiota in a case-control study with 50 SHS individuals and 50 matched healthy controls. Intestinal microbiota was analysed by MiSeq 250PE. Alpha diversity of intestinal microbiota in SHS individuals was higher compared with that of healthy controls (Simpson index, W = 2238, P = .048). Beta diversity was different between SHS and healthy controls …

Corrections To: The Effect Of Nordic Hamstring Exercise Intervention Volume On Eccentric Strength And Muscle Architecture Adaptations: A Systematic Journal Article And Meta-Analyses, Matthew Cuthbert, Nicholas Ripley, John J. Mcmahon, Martin Evans, G. Gregory Haff, Paul Comfort

Research outputs 2014 to 2021

No abstract provided.

Contralateral Effects By Unilateral Eccentric Versus Concentric Resistance Training, Wei-Chin Tseng, Kazunori Nosaka, Kuo-Wei Tseng, Tai-Ying Chou, Trevor C. Chen

Research outputs 2014 to 2021

Purpose: Unilateral resistance training increases muscle strength of the contralateral homologous muscle by the cross-education effect. Muscle damage induced by second eccentric exercise bout is attenuated, even when it is performed by the contralateral limb. The present study compared the effects of unilateral eccentric training (ET) and concentric training (CT) of the elbow flexors (EF) on maximal voluntary isometric contraction (MVC) strength and muscle damage of the contralateral untrained EF.

Methods: Young men were placed into ET, CT, ipsilateral repeated bout (IL-RB), and contralateral repeated bout (CL-RB) groups (n = 12 per group). The ET and CT groups performed …

Sharing Is Caring: A Study Of Food-Sharing Practices In Australian Early Childhood Education And Care Services, Ruth Wallace, Karen Lombardi, Charlotte De Backer, Leesa Costello, Amanda Devine

Research outputs 2014 to 2021

Food connects people, and can significantly impact the physical, social and emotional development of young children. Food sharing and family-style mealtimes can support healthy eating practices and psychological well-being among young children, and carersother than family members, such as Early Childhood Education and Care staff, play an important role in the provision of these practices. Despite increasing numbers of Australian children attending Early Childhood Education and Care services, there is often reluctance among staff to promote such mealtime practices, to the detriment of children's social and emotional development. The aim of this paper was to focus on the potential role …

Antimicrobial Resistance In Clostridium Difficile Ribotype 017, Korakrit Imwattana, Daniel R. Knight, Brian Kullin, Deirdre A. Collins, Papanin Putsathit, Pattarachai Kiratisin, Thomas V. Riley

Research outputs 2014 to 2021

Introduction:

Antimicrobial resistance (AMR) played an important role in the initial outbreaks of Clostridium difficile infection (CDI) in the 1970s. C. difficile ribotype (RT) 017 has emerged as the major strain of C. difficile in Asia, where antimicrobial use is poorly regulated. This strain has also caused CDI outbreaks around the world for almost 30 years. Many of these outbreaks were associated with clindamycin and fluoroquinolone resistance. AMR and selective pressure is likely to be responsible for the success of this RT and may drive future outbreaks.

Areas covered:

This narrative journalarticle summarizes the prevalence and mechanisms of AMR in …

The Relationship Between Abdominal Pain And Emotional Wellbeing In Children And Adolescents In The Raine Study, Oyekoya T. Ayonrinde, Oyedeji A. Ayonrinde, Leon A. Adams, Frank M. Sanfilippo, Therese A. O’ Sullivan, Monique Robinson, Wendy H. Oddy, John K. Olynyk

Research outputs 2014 to 2021

Abdominal pain is a common reason for medical visits. We examined the prevalence, gastrointestinal, and emotional significance of abdominal pain in a population-based cohort serially followed up from birth to 17 years. Children and adolescents from Generation 2 of the Raine Study participated in comprehensive cross-sectional assessments at ages 2, 5, 8, 10, 14 and 17 years. At 17 years, medical history, general health, gastrointestinal symptoms, medications, health practitioner attendance, and self-rated unhappiness were recorded. Longitudinal data regarding abdominal pain or unhappiness, from serial questionnaires, were analysed to identify factors associated with abdominal pain and adverse emotional health at age …

Effectiveness Of A Structured, Framework-Based Approach To Implementation: The Researching Effective Approaches To Cleaning In Hospitals (Reach) Trial, Lisa Hall, Nicole M. White, Michelle Allen, Alison Farrington, Brett G. Mitchell, Katie Page, Kate Halton, Thomas V. Riley, Christian A. Gericke, Nicholas Graves, Anne Gardner

Research outputs 2014 to 2021

BACKGROUND: Implementing sustainable practice change in hospital cleaning has proven to be an ongoing challenge in reducing healthcare associated infections. The purpose of this study was to develop a reliable framework-based approach to implement and quantitatively evaluate the implementation of evidence-based practice change in hospital cleaning. DESIGN/METHODS: The Researching Effective Approaches to Cleaning in Hospitals (REACH) trial was a pragmatic, stepped-wedge randomised trial of an environmental cleaning bundle implemented in 11 Australian hospitals from 2016 to 2017. Using a structured multi-step approach, we adapted the integrated Promoting Action on Research Implementation in Health Services (i-PARIHS) framework to support rigorous and …

Geographical Disparities In Screening And Cancer- Related Health Behaviour, Belinda Goodwin, Arlen K. Rowe, Fiona Crawford-Williams, Peter Baade, Suzanne K. Chambers, Nicholas Ralph, Joanne F. Aitken

Research outputs 2014 to 2021

This study aimed to identify whether cancer-related health behaviours including participation in cancer screening vary by geographic location in Australia. Data were obtained from the 2014–2015 Australian National Health Survey, a computer-assisted telephone interview that measured a range of health-related issues in a sample of randomly selected households. Chi-square tests and adjusted odds ratios from logistic regression models were computed to assess the association between residential location and cancer-related health behaviours including cancer screening participation, alcohol consumption, smoking, exercise, and fruit and vegetable intake, controlling for age, socio-economic status (SES), education, and place of birth. The findings show insufficient exercise, …

Sustaining Dancer Wellbeing Through Independent Professional Dance Careers, Luke S. Hopper, Peta Blevins, Shona Erskine, Danica Hendry, Raewyn Hill, Richard Longbottom

Research outputs 2014 to 2021

Dancers dedicate their lives to their art. The lucky few dancers who reach professional careers, must navigate a casualised industry, balance financial pressures and maintain performance fitness. This research aimed to provide practical considerations for dancers to support their health and wellbeing through independent, professional dance careers. Dancers from Australian contemporary dance company Co3 participated in a training program involving psychological and physiotherapy assessments and fitness training in conjunction with a major performance season. Focus groups with company dancers and staff investigated the perceived efficacy of the training program within the company schedule and in supporting dancer wellbeing. Dancers were …

Increasing Food Expenditure In Long Daycare By An Extra $0.50 Per Child/Day Would Improve Core Food Group Provision, Ros Sambell, Ruth Wallace, Johnny Lo, Leesa Costello, Amanda Devine

Research outputs 2014 to 2021

Early childhood education and care services are a significant feature of Australian family life, where nearly 1.4 million children attended a service in 2019. This paper reports on the cost of food provided to children in long day-care (LDC) services and extrapolates expenditure recommendations to support food provision compliance. A cross-sectional audit of LDC services in metropolitan Perth was conducted to determine food group provision by weighing raw ingredients of meal preparation—morning tea, lunch, and afternoon tea (MT, L, AT). Ingredients were costed at 2017 online metropolitan pricing from a large supermarket chain. Across participating services, 2 days of food …

Investigation Of The Association Between Dietary Fibre, Protein And Fat With Manganese Content In Food, Madhura Jayasinghe, Binosha Fernando, Subhashinie Senadheera, Pubudu Gunawardene, Somathilaka Ranaweera

Research outputs 2014 to 2021

Manganese deficiency may cause severe health disorders and is becoming prevalent in societies that are rapidly urbanising. Determining the Manganese contents and its relationship with the intake of protein, fibre and fats is important; which may allow people to select Manganese rich foods based on their major macronutrients. A cross-sectional study including detailed dietary assessment for two weeks, followed by proximate analysis of regularly consumed diets was conducted using 1200 adults from three different social segments as; lecturers/teachers (400), managerial employees in the private sector (400), and houses wives (400). Each social segment was assumed to elicit different lifestyles and …

Exploring The Association Between Recent Concussion, Subconcussive Impacts And Depressive Symptoms In Male Australian Football Players, Sarah Ann Harris, Paola T. Chivers, Fleur L. Mcintyre, Ben Piggott, Max Bulsara, Fiona H. Farringdon

Research outputs 2014 to 2021

Objectives: To explore the association between depressive symptoms and recent head-related trauma (diagnosed concussion, subconcussive impacts) in semiprofessional male Australian Football (AF) players.

Methods: Sixty-nine semiprofessional male players from a West Australian Football League (WAFL) club participated in the study (M age =21.81, SD=2.91 years). Depressive symptoms were measured using the Centre for Epidemiological Studies Depression Scale. Injuries and potential confounding variables (eg, pre-existing mental health condition; alcohol or drug hangovers; experiencing a stressful event) were self-reported anonymously using the WAFL Injury Report Survey. Both tools were administered every 2-weeks over the first 22-weeks of the WAFL season. Controlling for …

Predictors Of Ceasing Or Reducing Statin Medication Following A Large Increase In The Consumer Copayment For Medications: A Retrospective Observational Study, Karla Seamon, Frank Sanfilippo, Max Bulsara, Libby Roughead, Anna Kemp-Casey, Caroline Bulsara, Gerald F. Watts, David Preen

Research outputs 2014 to 2021

OBJECTIVES:

Previous Australian research has shown that following the 21% increase in patient copayments for medications on the Pharmaceutical Benefits Scheme (PBS) in 2005, the use of lipid-lowering therapy declined by 5%. This study aimed to determine the demographic and clinical characteristics of individuals who continued, reduced or ceased their use of statin medication in 2005.

STUDY TYPE:

Retrospective observational study using routinely collected administrative data.

METHOD:

We used pharmaceutical claims, hospital separations and mortality records from 2000 to 2005 for the Western Australian population. The cohort comprised stable users of statin medication in 2004. Based on changes in statin …

Bilingualism Is Associated With A Delayed Onset Of Dementia But Not With A Lower Risk Of Developing It: A Systematic Review With Meta-Analyses, Stefano Brini, Hamid R. Sohrabi, Jeffrey J. Hebert, Mitchell R.L. Forrest, Matti Laine, Heikki Hämäläinen, Mira Karrasch, Jeremiah Peiffer, Ralph Martins, Timothy J. Fairchild

Research outputs 2014 to 2021

Some studies have linked bilingualism with a later onset of dementia, Alzheimer’s disease (AD), and mild cognitive impairment (MCI). Not all studies have observed such relationships, however. Differences in study outcomes may be due to methodological limitations and the presence of confounding factors within studies such as immigration status and level of education. We conducted the first systematic review with meta-analysis combining cross-sectional studies to explore if bilingualism might delay symptom onset and diagnosis of dementia, AD, and MCI. Primary outcomes included the age of symptom onset, the age at diagnosis of MCI or dementia, and the risk of developing …

Correction To: Bilingualism Is Associated With A Delayed Onset Of Dementia But Not With A Lower Risk Of Developing It: A Systematic Review With Meta-Analyses, Stefano Brini, Hamid R. Sohrabi, Jeffrey J. Hebert, Mitchell R. L. Forrest, Matti Laine, Heikki Hämäläinen, Mira Karrasch, Jeremiah J. Peiffer, Ralph N. Martins, Timothy J. Fairchild

Research outputs 2014 to 2021

The original version of this article unfortunately contained the following mistakes. 1. In the Results section under the paragraph Disease Severity, the sentence “The PIs ranged between -0.47 and 0.57 MMSE points” should read -0.49 and 0.59 MMSE points. 2. In Figs. 3, 5, and 7, the labels “favour bilinguals” and “favours monolinguals” should be inverted. Therefore, it should be “favours monolinguals” and “favours bilinguals”. Please see below for the correct figures. © 2020, The Author(s).

The Gut Microbiota, Environmental Factors, And Links To The Development Of Food Allergy, Khui Hung Lee, Yong Song, Weidong Wu, Kan Yu, Guicheng Zhang

Research outputs 2014 to 2021

Food allergy appears to have its roots in an insufficient exposure to a diverse range of environmental microbiota during early life. Microbial exposure ensures the colonization of the gastrointestinal tract with commensal microbes, which is necessary for the induction of a balanced and tolerogenic immune function. High-throughput sequencing technology has facilitated in-depth studies of the gut microbiota as well as bacterial-derived metabolites. Although the role of the microbiota in allergies is now widely studied, its importance for food allergy was only recently noted. Studies in human cohorts have shown that there is an association of dysbiosis and pathogenesis of food …

The Effect Of Sleep Restriction, With Or Without High-Intensity Interval Exercise, On Myofibrillar Protein Synthesis In Healthy Young Men, Nicholas J. Saner, Matthew J. -C. Lee, Nathan W. Pitchford, Jujiao Kuang, Gregory D. Roach, Andrew Garnham, Tanner Stokes, Stuart M. Phillips, David J. Bishop, Jonathan D. Bartlett

Research outputs 2014 to 2021

Key points: Sleep restriction has previously been associated with the loss of muscle mass in both human and animal models. The rate of myofibrillar protein synthesis (MyoPS) is a key variable in regulating skeletal muscle mass and can be increased by performing high-intensity interval exercise (HIIE), although the effect of sleep restriction on MyoPS is unknown. In the present study, we demonstrate that participants undergoing a sleep restriction protocol (five nights, with 4 h in bed each night) had lower rates of skeletal muscle MyoPS; however, rates of MyoPS were maintained at control levels by performing HIIE during this period. …

Document Analysis Of Exertional Heat Illness Policies And Guidelines Published By Sports Organisations In Victoria, Australia, Prasanna J. Gamage, Caroline F. Finch, Lauren V. Fortington

Research outputs 2014 to 2021

Objectives To conduct a document and content analysis of exertional heat illness (EHI)-related documents published by sports organisations in Victoria, Australia, in order to determine their scope and evidence base against current international best practice recommendations. Methods A qualitative document and content analysis. Official documents relating to EHI were identified through a search of 22 Victorian sport organisation websites, supplemented by a general internet search. The content of these documents was evaluated against recommendations presented in three current international position statements on prevention and management of EHI. Results A range of document types addressing EHI were identified (n= 25), including …

South West Food Community: How Government And Community Initiatives Are Supporting Systemic Change Towards Enhanced Food Security, Stephanie Louise Godrich, Melissa Stoneham, Melinda Edmunds, Amanda Devine

Research outputs 2014 to 2021

Objective: Food security refers to adequate physical, social and economic access to food and is regarded as a complex, ‘wicked’ issue. This research aimed to understand the perspectives of initiative leaders (stakeholders), regarding their project relating to food security and its possession of characteristics associated with system change to enhance food security. Methods: Stakeholders (n=51) participated in semi-structured interviews that evaluated initiatives (n=52) against 36 desirable characteristics for system change. Transcripts were analysed using QSR NVivo and Wicked Lab’s Tool for Systemic Change. Results: Community-based initiatives often harnessed the passion of local communities to enhance food security through awareness-raising activities …

Limitations Of The Digestible Indispensable Amino Acid Score (Diaas) And Choice Of Statistical Reporting. Comment On “A Comparison Of Dietary Protein Digestibility, Based On Diaas Scoring, In Vegetarian And Non-Vegetarian Athletes. Nutrients 2019, 11, 3106”, Angela Genoni, Joel C. Craddock, Emma Strutt

Research outputs 2014 to 2021

No abstract provided.

Summary Of Tobacco Use Among Aboriginal And Torres Strait Islander Peoples, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

The Summary of tobacco use among Aboriginal and Torres Strait Islander peoples is a plain language publication that provides summarised and updated information from the Review of tobacco use among Aboriginal and Torres Strait Islander peoples(2020). It provides key information about tobacco use among Aboriginal and Torres Strait Islander peoples in a style that is easy to engage with and is particularly useful for health workers and those studying in the field as a quick source of general information about:

• the context of tobacco use and how common tobacco use is
• how smoking affects health
• the burden of disease …

Amylin And Beta Amyloid Proteins Interact To Form Amorphous Heterocomplexes With Enhanced Toxicity In Neuronal Cells, Prashant Bharadwaj, Tanya Solomon, Bikash Sahoo, Katarzyna Ignasiak, Scott Gaskin, Joanne Rowles, Guiseppe Verdile, Mark Howard, Charles S. Bond, Ayyalusamy Ramamoorthy, Ralph Martins, Philip Newsholme

Research outputs 2014 to 2021

Human pancreatic islet amyloid polypeptide (hIAPP) and beta amyloid (Aβ) can accumulate in Type 2 diabetes (T2D) and Alzheimer’s disease (AD) brains and evidence suggests that interaction between the two amyloidogenic proteins can lead to the formation of heterocomplex aggregates. However, the structure and consequences of the formation of these complexes remains to be determined. The main objective of this study was to characterise the different types and morphology of Aβ-hIAPP heterocomplexes and determine if formation of such complexes exacerbate neurotoxicity. We demonstrate that hIAPP promotes Aβ oligomerization and formation of small oligomer and large aggregate heterocomplexes. Co-oligomerized Aβ42-hIAPP mixtures …

Summary Of Cardiovascular Health Among Aboriginal And Torres Strait Islander People, Australian Indigenous Healthinfonet

Research outputs 2014 to 2021

This Summary describes different types of cardiovascular disease (CVD) and how common they are among Aboriginal and Torres Strait Islander people. It highlights the differences in how groups of Aboriginal and Torres Strait Islander people – such as women and men, or older and younger people – experience CVD. It describes some improvements in the cardiovascular health of Aboriginal and Torres Strait Islander people. It also gives examples of the many good things that are being done on the ground to prevent illness and improve CVD care for Aboriginal and Torres Strait Islander people.

The Influence Of Biological Maturity On Dynamic Force–Time Variables And Vaulting Performance In Young Female Gymnasts, Sylvia Moeskops, Jon L. Oliver, Paul J. Read, John B. Cronin, Gregory D. Myer, G. Gregory Haff, Isabel S. Moore, Rhodri S. Lloyd

Research outputs 2014 to 2021

Purpose: This cross-sectional study investigated dynamic force–time variables and vaulting performance in young female gymnasts of different maturity status.

Methods: 120 gymnasts aged 5–14 years were sub-divided into maturity groupings using percent of predicted adult height (%PAH) attained. Participants performed three jumping protocols, the squat jump (SJ), countermovement jump (CMJ) and drop jump (DJ), before completing straight jump vaults that were recorded using two-dimensional video.

Results: Jumping performance improved with biological maturity evidenced by the most mature gymnasts’ producing significantly more absolute force (P < 0.05; all d > 0.78), impulse (P < 0.05; all d > 0.75) and power (P < 0.05; all d > 0.91) than the least mature group, resulting in the …

Hunger For Learning Or Tasting? An Exploratory Study Of Food Tourist Motivations Visiting Food Museum Restaurants, Eerang Park, Sangkyun Kim, Min Xu

Research outputs 2014 to 2021

Background: To allow for accurate and timely diagnosis of developmental coordination disorder (DCD) key stakeholders must be familiar with and be able to identify features of this disorder. No studies to date have investigated the awareness of DCD among key stakeholders in Australia.

Methods: An online survey was complete by 494 Australian participants: primary caregivers (n = 153), teachers (n = 149), allied health professionals (n = 165) and medical professionals (n = 27).

Results: DCD and related terms were among the least known childhood disorders. Approximately half of the sample were familiar with the term DCD but every stakeholder …

We Have The Program, What Now? Development Of An Implementation Plan To Bridge The Research-Practice Gap Prevalent In Exercise Oncology, Mary A. Kennedy, Sara Bayes, Robert U. Newton, Yvonne Zissiadis, Nigel A. Spry, Dennis R. Taaffe, Nicolas H. Hart, Michael Davis, Aileen Eiszele, Daniel A. Galvão

Research outputs 2014 to 2021

© 2020 The Author(s). Background: Exercise has emerged as a promising therapy for people with cancer. Novel programs have been developed to translate research into practice; however, implementation barriers have limited their success in part because successful translation of exercise oncology research into practice requires context-specific implementation plans. The aim of this study was to employ the implementation mapping protocol to develop an implementation plan to support programming of a co-located exercise clinic and cancer treatment center. Methods: The Implementation Mapping protocol, which consists of five specific iterative tasks, was used. A stakeholder advisory group advised throughout the process. Results: …

Impact Of Commuting Mode On Obesity Among A Working Population In Beijing, China: Adjusting For Air Pollution, Yue Liu, Lixin Tao, Jie Zhang, Jia Liu, Haibin Li, Xiangtong Liu, Yanxia Luo, Jingbo Zhang, Wei Wang, Xiuhua Guo

Research outputs 2014 to 2021

© 2020 Liu et al. Background: Few studies have considered the interplay between commuting mode and air pollution on obesity. The aim of this study was to examine whether workplace air pollutants exposure modifying the associations between different commuting mode and obesity. Methods: A cross-sectional study of workers in Beijing was conducted in 2016. The study sample comprised 10,524 participants aged 18 to 65 years old. Outcomes were defined as overall obesity (BMI ≥ 28 kg/m2) and abdominal obesity (WC ≥ 85 cm in men and WC ≥ 80 cm in women). Commuting modes were divided into walking, cycling, bus, …

Experiences Of Parents Who Give Pharmacological Treatment To Children With Functional Constipation At Home, Gunilla Flankegård, Evalotte Mörelius, Karel Duchen, Patrik Rytterström

Research outputs 2014 to 2021

© 2020 The Authors. Journal of Advanced Nursing published by John Wiley & Sons Ltd Aim: The aim was to explore the lived experiences of parents who give oral and rectal pharmacological treatment to their children with functional constipation at home. Design: A phenomenological design with a reflective lifeworld research approach that describes phenomena as they are experienced by individuals. Methods: From January–May 2019, 15 interviews were conducted with parents of children with functional constipation with home-based oral and rectal treatment. Parents were recruited from three different healthcare levels. Open-ended questions were used starting from the description of a normal …

Modification Of Diet, Exercise And Lifestyle (Model) Study: A Randomised Controlled Trial Protocol, Simone Radavelli-Bagatini, Catherine P. Bondonno, Marc Sim, Lauren C. Blekkenhorst, Reindolf Anokye, Emma Connolly, Nicola P. Bondonno, John T. Schousboe, Richard J. Woodman, Kun Zhu, Pawel Szulc, Ben Jackson, James Dimmock, Markus P. Schlaich, Kay L. Cox, Douglas P. Kiel, Wai H. Lim, Mandy Stanley, Amanda Devine, Peter L. Thompson, Jenny Gianoudis, Belinda De Ross, Robin M. Daly, Joshua Lewis, Jonathan M. Hodgson

Research outputs 2014 to 2021

Introduction Most cardiovascular disease (CVD)-related events could be prevented or substantially delayed with improved diet and lifestyle. Providing information on structural vascular disease may improve CVD risk factor management, but its impact on lifestyle change remains unclear. This study aims to determine whether providing visualisation and pictorial representation of structural vascular disease (abdominal aortic calcification (AAC)) can result in healthful diet and lifestyle change.

Methods and analysis This study, including men and women aged 60–80 years, is a 12-week, two-arm, multisite randomised controlled trial. At baseline, all participants will have AAC assessed from a lateral spine image captured using a …