Medicine and Health Sciences Commons^™

Effects Of Oral Magnesium Supplementation On Insulin Resistance And Type 2 Diabetes Mellitus, Renea L. Beckstrand, Loandra Berg

Faculty Publications

The purpose of this study was to examine the relationship of magnesium levels related to insulin resistance and type 2 diabetes mellitus. Diabetes is a metabolic disease in which the body does not produce or correctly use insulin to maintain proper levels of glucose in the blood resulting in serious health consequences. Diabetes is a major factor in coronary heart disease, stroke as well as blindness, kidney failure, and non-traumatic amputations due to disruption of the microvascular system (Schulze & Hu, 2005). The Center for Disease Control reported in 2007: 23.6 million people in the United States (7.8% of the …

Life Experiences Of Women With Cerebral Palsy Who Have Experienced Mistreatment, Catherine Coverston, Donna S. Freeborn, Barbara L. Mandleco, Mary Ann Curry, Kathleen A. Knafl

Faculty Publications

The purpose of this study was to describe the life experiences of women with cerebral palsy who have experienced mistreatment and also describe how these women understand the meaning of their disability and mistreatment experiences relative to gender, culture, social class, and power.

The Incidence Of Postpartum Depression Among Hispanic Women, Renea L. Beckstrand, Ana C. Birkhead, Lynn Clark Callister, Nissa Lucero, Glauco Souza

Faculty Publications

There is a lack of sufficient knowledge concerning the prevalence of postpartum depression (PPD) among Hispanic women. The purpose of this quantitative descriptive study was to evaluate the incidence of PPD among Hispanic women.

Estimating Dysphonia Severity In Continuous Speech: Application Of A Multi-Parameter Spectral/Cepstral Model, Christopher Dromey, Shaheen N. Awan, Nelson Roy

Faculty Publications

The purpose of the study was to identify a sub-set of spectral/cepstral-based analysis methods that would most effectively predict dysphonia severity (as estimated via auditory-perceptual analysis) in samples of continuous speech. Acoustic estimates of dysphonia severity were used as an objective treatment outcomes measure in a set of pre- vs post-treatment speech samples. Pre- and post-treatment continuous speech samples from 104 females with primary muscle tension dysphonia (MTD) were rated by listeners using a 100 point visual analogue scale (VAS) and analysed acoustically with spectral/cepstral-based measures. Stepwise linear regression produced a three-factor model consisting of the cepstral peak prominence (CPP); …

Fiber’S Impact On High-Sensitivity C-Reactive Protein Levels In Cardiovascular Disease, Renea L. Beckstrand, Jennifer L. Butcher

Faculty Publications

The purpose of this study was to determine if increased dietary or supplemental intake of fiber slows or prevents inflammation as evidenced by hs-CRP values.

Understanding Why Professional Nurses Work, Patricia Rushton, Dennis L. Eggett

Faculty Publications

The project studied factors impacting professional registered nurses in maintaining active employment. Participants chose to enter the nursing profession to provide service. They were motivated to stay in the nursing profession in an employed situation to 1) provide financial support of themselves and their families,and 2) from a desire to serve. Respect as individuals was motivation to do their best work. The results of the study reinforce the desire of the nursing profession to serve its clients and patients. The results demonstrate the committment of registered nurses to the nursing profession. They also demonstrate the desire of professional nurses to …

Nps' Perceptions Of Disaster Preparedness Education: Quantitative Survey Research, Milada Tichy, A. Elaine Bond, Renea L. Beckstrand, Barbara Heise

Faculty Publications

Nurse practitioners need to be effective in responding to large-scale natural and man-made disasters. However, disaster core competencies for NPs are largely nonexistent. The purpose of this study was to assess NPs' level of disaster preparedness and determine how NPs acquired knowledge about disaster preparation. Findings suggest that a consistent national NP curriculum for disaster preparedness, including communication with other disaster agencies, is needed. With proper education, NPs can play a major role in disaster management.

Laryngeal Level Amplitude Modulation In Vibrato, Christopher Dromey, Lorie Reese, J. Arden Hopkin

Faculty Publications

Objectives: The goal of this investigation was to test a new methodology for measuring amplitude modulation (AM) at the level of the vocal folds during vibrato in trained singers, because previous research has suggested that AM arises in large part as an acoustic epiphenomenon through an interaction of the harmonics in the laryngeal source with the resonances of the vocal tract as the fundamental frequency oscillates.
Study Design: A within-subjects model was used to compare vocal activity across three pitch and three loudness conditions.
Methods: Seventeen female singers with a range of training and experience were recorded with a microphone …

Intra-Speaker Variability In Palatometric Measures Of Consonant Articulation, Christopher Dromey, Marybeth Sanders

Faculty Publications

Electropalatometry is a useful clinical and research tool for measuring linguapalatal contact. The goal of this study was to examine intra-speaker variability in performance. Twenty individuals spoke VCV nonsense words using a schwa in the initial position, the 15 palatal consonants, and three corner vowels, /ɑ/, /i/, /u/. A variability index was created to examine speaker consistency.
Different aspects of articulation (i.e. place, manner, voicing, coarticulation) were compared. Significant differences for variability were found for place of articulation in the /i/ vowel context and for manner of articulation in the /ɑ/ vowel context. Also for the /ɑ/ vowel, significant differences …

An In Vivo Model Of External Superior Laryngeal Nerve Paralysis: Laryngoscopic Findings, Christopher Dromey, Michael E. Barton, Marshall E. Smith, Ray M. Merrill, Cara Sauder, Nelson Roy

Faculty Publications

Objectives/Hypothesis: For over 100 years, a controversy has existed regarding the laryngeal signs that should be considered pathognomonic of unilateral external superior laryngeal nerve (ESLN) paralysis. By selectively blocking the ESLN using lidocaine, we attempted to identify the salient laryngeal features associated with acute, unilateral cricothyroid(CT) muscle dysfunction. Study Design: Prospective, repeated measures, experimental design. Methods: Ten vocally normal adult males under-went lidocaine block of the right ESLN with laryngeal electromyography verification. Flexible videolaryngostroboscopic (FVLS) recordings were acquired before and during the block. Eleven blinded, expert judges, rated randomized pre- versus during block recordings of 10 vocal tasks using standardized …

Articulatory Changes In Muscle Tension Dysphonia: Evidence Of Vowel Space Expansion Following Manual Circumlaryngeal Therapy, Christopher Dromey, Nelson Roy, Shawn L. Nissen, Shimon Sapir

Faculty Publications

In a preliminary study, we documented significant changes in formant transitions associated with successful manual circumlaryngeal treatment (MCT) of muscle tension dysphonia (MTD), suggesting improvement in speech articulation. The present study explores further the effects of MTD on vowel articulation by means of additional vowel acoustic measures. Pre- and post-treatment audio recordings of 111 women with MTD were analyzed acoustically using two measures: vowel space area (VSA) and vowel articulation index (VAI), constructed using the first (F1) and second (F2) formants of 4 point vowels/ ", i, æ, u/, extracted from eight words within a standard reading passage. Pairwise t-tests …

Acoustic And Spectral Patterns In Young Children’S Stop Consonant Productions, Shawn L. Nissen, Robert Allen Fox

Faculty Publications

The aim of this study was to examine the acoustic and spectral patterns of stop articulation in the speech of pre-pubescent children. A set of voiceless stop consonants, /ptk/, produced by a group of adults and typically developing children 3–5 years of age were examined in terms of multiple acoustic and spectral parameters. Findings indicated that, with the exception of spectral kurtosis, the acoustic and spectral characteristics of the stop productions varied significantly as a function of place of articulation and vowel context. Sex-specific differences in spectral slope, mean, and skewness were found for the 5-year-old and adult speakers. Such …

Social Or Academic Language Intervention? You Don’T Have To Choose, Lee Robinson

Faculty Publications

Students with a variety of types of language impairments exhibit deficits that affect both social interactions and academic performance. Two types of theory of mind underlie social and academic language skills: interpersonal and intrapersonal. In this article, the authors describe strategies for developing interpersonal and intrapersonal theory of mind abilities with the goal of promoting the inferencing skills essential for comprehension of social and academic language.

Parental Hesitation As A Factor In Delayed Childhood Immunization, Karlen E. (Beth) Luthy, Renea L. Beckstrand, Neil E. Peterson

Faculty Publications

Introduction: One reason for lower immunization rates is that some parents hesitate to have their children immunized. A hesitancy questionnaire was developed to identify reasons parents hesitate in having their children immunized.

Methods: The hesitancy questionnaire was distributed from local pediatric and family practice offices and from the area's county health department. To be eligible, participants needed to be present in the clinic with a child needing a minimum of one immunization that was at least 6 months overdue.

Results: When questioned why their child was overdue for immunizations, the most common response was that participants were confused about the …

Teaching The Teacher Program To Assist Nurse Managers To Educate Nursing Staff In Ecuadorian Hospitals, Sheri P. Palmer, Sondra Heaston

Faculty Publications

Continuing education for hospital staff nurses is a concern worldwide. Current research shows that continuing education among nurses can positively affect patient outcomes (O’Brien, T., Freemantle, N., Oxman, A, et al., 2002. Interactive continuing education workshops or conferences can improve professional practice and patient outcomes. Journal of Evidence Based Nursing. 26 (5)). Seeing a need for improved patient outcomes among hospitals in Ecuador, we conducted a teaching the teacher program to assist nurse managers to carry-out continuing education in their hospital system. This teaching the teacher program was established through the collaboration between one College of Nursing in Utah, USA …

Computerized Visually Presented Story Recall Tasks: Effects On Performance In Dementia, Nidhi Mahendra, Nisha Engineer, Susan Carroll

Faculty Publications

No abstract provided.

Breast Cancer Fatalism: The Role Of Women's Perceptions Of The Health Care System, Allyson G. Hall, Amal J. Khoury, Ellen D.S. Lopez, Nedra Lisovicz, Amanda Avis-Williams, Amal K. Mitra

Faculty Publications

Cancer fatalism, which can be understood as the belief that cancer is a death sentence, has been found to be a deterrent to preventive cancer screening participation. This study examines factors associated with breast cancer fatalism among women. We analyzed data from a 2003 survey of women 40 years of age. The survey collected information about respondents' knowledge and attitudes regarding breast health. Analyses compared the characteristics of women who reported and those who did not report a fatalistic attitude. Women with a fatalistic attitude were more likely to be African American, to have a family history of breast cancer, …

Neuroimaging And Recovery Of Language In Aphasia, Cynthia K. Thompson, Dirk B. Den Ouden

Faculty Publications

The use of functional neuroimaging techniques has advanced what is known about the neural mechanisms used to support language processing in aphasia resulting from brain damage. This paper highlights recent findings derived from neuroimaging studies focused on neuroplasticity of language networks, the role of the left and right hemispheres in this process, and studies examining how treatment affects the neurobiology of recovery. We point out variability across studies as well as factors related to this variability, and we emphasize challenges that remain for research.

Cardiorespiratory Fitness As A Predictor Of Fatal And Nonfatal Stroke In Asymptomatic Women And Men, Steven P. Hooker, Xuemei Sui, Natalie Colabianchi, John E. Vena, James N. Laditka, Michael J. Lamonte, Steven N. Blair

Faculty Publications

Background and Purpose - Prospective data on the association between cardiorespiratory fitness (CRF) and stroke are largely limited to studies in men or do not separately examine risks for fatal and nonfatal stroke. This study examined the association between CRF and fatal and nonfatal stroke in a large cohort of asymptomatic women and men.

Methods - A total of 46,405 men and 15,282 women without known myocardial infarction or stroke at baseline completed a maximal treadmill exercise test between 1970 and 2001. CRF was grouped as quartiles of the sex-specific distribution of maximal metabolic equivalents achieved. Mortality follow-up was through …

Weight Regain Is Related To Decreases In Physical Activity During Weight Loss, Xuewen Wang, Mary F. Lyles, Tongjian You, Michael J. Berry, Jack Rejeski, Barbara J. Nicklas

Faculty Publications

Purpose—To examine whether adaptations in physical activity energy expenditure (PAEE) and resting metabolic rate (RMR) during weight loss were associated with future weight regain in overweight/obese, older women.

Research Methods and Procedures—Thirty-four overweight/obese (BMI=25–40 kg/m²), postmenopausal women underwent a 20-week weight loss intervention of hypocaloric diet with (low- or high-intensity) or without treadmill walking (weekly caloric deficit was ~11760 kJ), with a subsequent 12-month follow-up. RMR (via indirect calorimetry), PAEE (by RT3 accelerometer) and body composition (by DXA) were measured before and after intervention. Body weight and self-reported information on physical activity were collected after intervention, …

Repression Of The Sumo-Specific Protease Senp1 Induces P53-Dependent Premature Senescence In Normal Human Fibroblasts, Kristin E. Yates, Gregory A. Korbel, Michael Shtutman, Igor Roninson, Daniel Dimaio

Faculty Publications

The proliferative lifespan of normal somatic human cells in culture terminates in a permanent growth-arrested state known as replicative senescence. In this study, we show that RNA interference-mediated repression of the genes encoding the small ubiquitin-related modifier (SUMO)-specific proteases, Senp1, Senp2, and Senp7, induced low passage primary human fibroblasts to senesce rapidly. Following Senp1 repression, we observed a global increase in sumoylated proteins and in the number and size of nuclear SUMO-containing promyelocytic leukemia (PML) bodies. SUMO/PML bodies also increased during replicative senescence. p53 transcriptional activity was enhanced towards known p53 target genes following repression of Senp1, and inhibition of …

Does Place Explain Racial Health Disparities? Quantifying The Contribution Of Residential Context To The Black/White Health Gap In The United States, Brian K. Finch, D. Phuong Do, Ricardo Basurto-Davila, Chloe E. Bird, José J. Escarce, Nicole Lurie

Faculty Publications

The persistence of the black health disadvantage has been a puzzling component of health in the United States in spite of general declines in rates of morbidity and mortality over the past century. Studies that have focused on well-established individual-level determinants of health such as socio-economic status and health behaviors have been unable to fully explain these disparities. Recent research has begun to focus on other factors such as racism, discrimination, and segregation. Variation in neighborhood context - socio-demographic composition, social aspects, and built environment - has been postulated as an additional explanation for racial disparities, but few attempts have …

Breast Cancer Survival Among Economically Disadvantaged Women: The Influences Of Delayed Diagnosis And Treatment On Mortality, Emily Rose Smith, Swann Arp Adams, Irene Prabhu Das, Matteo Bottai, Jeanette Fulton, James R. Hébert

Faculty Publications

Breast cancer affects thousands each year in the United States, and disproportionately affects certain subgroups. For example, the incidence of breast cancer in South Carolina is lower in African American compared with European American women by ~12% to 15%, but their mortality rate is twice as high as in European American women. The purpose of the study was to assess factors associated with breast cancer mortality between African American and European American women. Participants (n = 314) in South Carolina's Breast and Cervical Cancer Early Detection Program (SCBCCEDP), which provides breast cancer screening and treatment services, during the years …

Human Embryonic Stem Cell Research, Justice, And The Problem Of Unequal Biological Access, Mark Moller

Faculty Publications

No abstract provided.

Cost-Efficient Treatment Options For Uninsured Or Underinsured Patients For Five Common Conditions, Karlen E. (Beth) Luthy, Neil E. Peterson, Joey Wilkinson

Faculty Publications

The nurse practitioner's (NP's) role in providing quality care continues to evolve, concurrent with the ever-evolving health care system. With an influx of uninsured and underinsured patients, NPs must not only provide high-quality health care, they must also address cost-efficient treatment options for patients who cannot afford expensive medications. Familiarity with the cost of medications and prescribing cost-efficient medications are valuable tools NPs can use to encourage patient compliance with a specific care regimen, consequently improving the overall health of uninsured or underinsured individuals. Knowledge of patient assistance programs may also assist NPs in decreasing prescription drug costs for patients. …

Light-Dependant Biostabilisation Of Sediments By Stromatolite Assemblages, David M. Paterson, Rebecca J. Aspden, Pieter T. Visscher, Mireille Consalvey, Miriam S. Andres, Alan W. Decho, John F. Stolz, R. Pamela Reid

Faculty Publications

For the first time we have investigated the natural ecosystem engineering capacity of stromatolitic microbial assemblages. Stromatolites are laminated sedimentary structures formed by microbial activity and are considered to have dominated the shallows of the Precambrian oceans. Their fossilised remains are the most ancient unambiguous record of early life on earth. Stromatolites can therefore be considered as the first recognisable ecosystems on the planet. However, while many discussions have taken place over their structure and form, we have very little information on their functional ecology and how such assemblages persisted despite strong eternal forcing from wind and waves. The capture …

The Community-Driven Approach To Environmental Exposures: How A Community-Based Participatory Research Program Analyzing Impacts Of Environmental Exposure On Lupus Led To A Toxic Site Cleanup, Julien A. Terrell, Edith M. Williams, Christine M. Murekeyisoni, Robert Watkins, Laurene Tumiel-Berhalter

Faculty Publications

Community-based participatory research (CBPR) is a mechanism to improve environmental quality in communities primarily inhabited by minorities or low income families. A collaborative partnership between the University at Buffalo and the Toxic Waste Lupus Coalition was formed to investigate the high prevalence of lupus in the area and whether cases of disease were linked to chemicals found at a nearby New York State Superfund site in East Buffalo. The purpose of the study was to use CBPR practices to educate impacted residents and enable their participation in efforts to get a nearby contaminated waste site remediated. Community members were active …

Gender Differences In The Risk Of Hiv Infection Among Persons Reporting Abstinence, Monogamy, And Multiple Sexual Partners In Northern Tanzania, Keren Z. Landman, Jan Ostermann, John A. Crump, Anna Mgonja, Meghan K. Mayhood, Dafrosa K. Itemba, Alison C. Tribble, Evaline M. Ndosi, Helen Y. Chu, John F. Shao, John A. Bartlett, Nathan M. Thielman

Faculty Publications

Background: Monogamy, together with abstinence, partner reduction, and condom use, is widely advocated as a key behavioral strategy to prevent HIV infection in sub-Saharan Africa. We examined the association between the number of sexual partners and the risk of HIV seropositivity among men and women presenting for HIV voluntary counseling and testing (VCT) in northern Tanzania.

Methodology/ Principal Findings: Clients presenting for HIV VCT at a community-based AIDS service organization in Moshi, Tanzania were surveyed between November 2003 and December 2007. Data on sociodemographic characteristics, reasons for testing, sexual behaviors, and symptoms were collected. Men and women were categorized by …

Exposure To Smoking Imagery In Popular Films And Adolescent Smoking In Mexico, James F. Thrasher, Christine Jackson, Edna Arillo-Santillán, James D. Sargent

Faculty Publications

Background: Exposure to smoking imagery in films in consistently associated with smoking behavior and its psychological antecedents among adolescents in high-income countries, but its association with adolescent smoking in middle-income countries is unknown.

Methods: In 2006, a cross-sectional sample of 3876 Mexican adolescents in secondary school was surveyed on smoking behavior, smoking risk factors, and exposure to 42 popular films that contained smoking. Participants were classified into quartiles of exposure to smoking imagery across all films they reported having seen. Models were estimated to determine associations among quartiles of film-smoking exposure, smoking behavior, and the psychological antecedents of smoking, adjusting …

Association Between Muscular Strength And Mortality In Men: Prospective Cohort Study, Jonatan R. Ruiz, Xuemei Sui, Felipe Lobelo, James R. Morrow Jr., Allen W. Jackson, Michael Sjöström, Steven N. Blair

Faculty Publications

Objective: To examine prospectively the association between muscular strength and mortality from all causes, cardiovascular disease, and cancer in men.

Design: Prospective cohort study.

Setting: Aerobics center longitudinal study.

Participants: 8762 men aged 20-80.

Main outcome measures: All cause mortality up to 31 December 2003; muscular strength, quantified by combining one repetition maximal measures for leg and bench presses and further categorised as age specific thirds of the combined strength variable; and cardiorespiratory fitness assessed by a maximal exercise test on a treadmill.

Results: During an average follow-up of 18.9 years, 503 deaths occurred (145 cardiovascular disease, 199 cancer). Age …