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Articles 31 - 60 of 88
Full-Text Articles in Medicine and Health Sciences
Culture Systems: Embryo Culture And Monozygotic Twinning, Amy Sparks
Culture Systems: Embryo Culture And Monozygotic Twinning, Amy Sparks
Amy E.T. Sparks
The incidence of monozygotic twinning in pregnancies achieved with assisted reproductive technologies (ART) is significantly higher than spontaneously conceived pregnancies. The factors associated with ART that predispose the embryos to splitting are not well-characterized. Assisted hatching and extended embryo culture are two ART laboratory methods that have been risk factors for monozygotic twinning. The methods and strategies that may be employed to avoid monozygotic twinning are discussed in this chapter.
Are Environmental Levels Of Bisphenol A Associated With Reproductive Function In Fertile Men?, J. Mendiola, N. Jorgensen, A. Andersson, A. Calafat, X. Ye, J. Redmon, E. Drobnis, C. Wang, Amy Sparks, S. Thurston, F. Liu, S. Swan
Are Environmental Levels Of Bisphenol A Associated With Reproductive Function In Fertile Men?, J. Mendiola, N. Jorgensen, A. Andersson, A. Calafat, X. Ye, J. Redmon, E. Drobnis, C. Wang, Amy Sparks, S. Thurston, F. Liu, S. Swan
Amy E.T. Sparks
BACKGROUND: Rodent and in vitro studies have demonstrated the estrogenicity of bisphenol A (BPA). However, few studies have examined the relationship between human exposure to BPA and male reproductive function. OBJECTIVES: We investigated the relationships between environmental BPA exposure and reproductive parameters, including semen quality and male reproductive hormones, in prospectively recruited fertile men. METHODS: Participants (n = 375) were partners of pregnant women who participated in the Study for Future Families in four U.S. cities, and all of the men provided blood, semen, and urine samples. BPA was measured in urine. Serum samples were analyzed for reproductive hormones, including …
Effects Of Time Of Deoxyribonucleic Acid Microinjection On Gene Detection And In Vitro Development Of Bovine Embryos, Amy Sparks, R. Canseco, C. Russell, J. Johnson, H. Moll, W. Velander, F. Gwazdauskas
Effects Of Time Of Deoxyribonucleic Acid Microinjection On Gene Detection And In Vitro Development Of Bovine Embryos, Amy Sparks, R. Canseco, C. Russell, J. Johnson, H. Moll, W. Velander, F. Gwazdauskas
Amy E.T. Sparks
In vivo fertilized embryos were surgically collected from superovulated dairy cows to evaluate microinjection on embryo development and utilized the polymerase chain reaction technique for selection of transgenic embryos. Seventy-two percent of the embryos with visible pronuclei or nuclei were microinjected with DNA, and the remaining 28% served as uninjected controls. All embryos were cocultured with bovine oviductal epithelial cells. Mean final development scores of embryos within the same initial cell stage at collection were unaffected by microinjection. After 144 h of culture, 45% of the microinjected embryos developed to the morula or blastocyst stage. The transgene was detected in …
Influence Of Bedrest Or Ambulation In The Clinical Treatment Of Acute Deep Vein Thrombosis On Patient Outcomes: A Review And Synthesis Of The Literature, V. Gay, R. Hamilton, S. Heiskell, Amy Sparks
Influence Of Bedrest Or Ambulation In The Clinical Treatment Of Acute Deep Vein Thrombosis On Patient Outcomes: A Review And Synthesis Of The Literature, V. Gay, R. Hamilton, S. Heiskell, Amy Sparks
Amy E.T. Sparks
A thorough review of current and classic literature was completed to distinguish the influence of bedrest or ambulation on patient treatment outcomes with confirmed deep vein thrombosis.
Varix Size Correlates With Improvement In Total Motile Sperm/Ejaculate And Pregnancy Rates., O. Snyder, J. Sandlow, M. Zenni, J. Donovan, Amy Sparks
Varix Size Correlates With Improvement In Total Motile Sperm/Ejaculate And Pregnancy Rates., O. Snyder, J. Sandlow, M. Zenni, J. Donovan, Amy Sparks
Amy E.T. Sparks
No abstract provided.
Comparison Of Microscopic Epididymal Sperm Aspiration And Intracytoplasmic Sperm Injection/In-Vitro Fertilization With Repeat Microscopic Reconstruction Following Vasectomy: Is Second Attempt Vas Reversal Worth The Effort?, J. Donovan, M. Dibaise, Amy Sparks, J. Kessler, J. Sandlow
Comparison Of Microscopic Epididymal Sperm Aspiration And Intracytoplasmic Sperm Injection/In-Vitro Fertilization With Repeat Microscopic Reconstruction Following Vasectomy: Is Second Attempt Vas Reversal Worth The Effort?, J. Donovan, M. Dibaise, Amy Sparks, J. Kessler, J. Sandlow
Amy E.T. Sparks
Since 1986, we have performed microscopic reconstruction in 18 men following failed microscopic vasectomy reversal. Between 1994 and 1996, nine couples have undergone microscopic epididymal sperm aspiration (MESA)/ intracytoplasmic sperm injection (ICSI) treatment for male infertility due either to congenital absence of the vas deferens (CAVD) or inoperable excurrent duct obstruction. We compared the cost efficiency of repeat vasectomy reversal to that for MESA combined with ICSI/in-vitro fertilization (ICSI/IVF). The cost of male partner procedures (vasectomy reversal, MESA) was based on physician and hospital charges, while the cost of ICSI/IVF included preparation of the female partner (medications and physician charges) …
Ovulation Rate, Zygote Recovery And Follicular Populations In Fsh-Superovulated Goats Treated With Pgf(2-Alpha) And/Or Gnrh, R. Krisher, F. Gwazdauskas, R. Page, C. Russell, R. Canseco, Amy Sparks, W. Velander, J. Johnson, R. Pearson
Ovulation Rate, Zygote Recovery And Follicular Populations In Fsh-Superovulated Goats Treated With Pgf(2-Alpha) And/Or Gnrh, R. Krisher, F. Gwazdauskas, R. Page, C. Russell, R. Canseco, Amy Sparks, W. Velander, J. Johnson, R. Pearson
Amy E.T. Sparks
Follicular development and ovulation were examined in superovulated Nubian and Nubian-cross dairy goats following prostaglandin F-2 alpha (PGF(2 alpha)) and/or gonadotropin releasing hormone (GnRH) treatment. Estrus was synchronized with Synchromate-B(R) implants. Superovulation was induced with follicle stimulating hormone (FSH) and augmented with GnRH and/or PGF(2 alpha). The PGF(2 alpha) treatment was administered on Day 2 of superovulation. Implants were removed from all goats on Day 3 of superovulation. The GnRH treatment was administered 24 h after implant removal. All does were exposed to fertile males for 48 h at the time of GnRH injection. Surgical embryo recovery and ovarian response …
'Old' Bones In Young Bodies: The Tale Of Cystic Fibrosis, Amy Sparks, S. Mcgee, C. Boone, I. Neuringer, S. Jones, R. Aris
'Old' Bones In Young Bodies: The Tale Of Cystic Fibrosis, Amy Sparks, S. Mcgee, C. Boone, I. Neuringer, S. Jones, R. Aris
Amy E.T. Sparks
PURPOSE OF REVIEW: Cystic fibrosis (CF) is the most common genetic disease within the white population and leads to premature respiratory failure. Approximately, 60 000 individuals are currently living with CF in North America and Europe, almost half of whom are adults. RECENT FINDINGS: Dozens of studies across the globe indicate that CF adults have low bone density and increased rates of fractures. This genesis of the problem appears to be in late childhood to adolescence. SUMMARY: Prevention and treatment of CF-related bone disease must address the myriad risk factors (decreased absorption of fat-soluble vitamins due to pancreatic insufficiency, altered …
Gamete Microsurgery For Assisted Fertilization, Amy Sparks
Gamete Microsurgery For Assisted Fertilization, Amy Sparks
Amy E.T. Sparks
Several methods of gamete microsurgery have been proposed to facilitate the union of the spermatozoon and oocyte in infertile couples, Partial zona dissection, subzonal sperm insertion, and intracytoplasmic sperm insertion are the three techniques currently being used for assisted fertilization in human in vitro fertilization laboratories. Fertilization and pregnancy rates after partial zona dissection and subzonal insertion have been Variable and rather low. Recent reports of relatively high fertilization and pregnancy rates achieved after intracytoplasmic sperm insertion have rejuvenated interest in gamete microsurgery. Methods for each procedure are described, Studies which have attempted patient selection for gamete microsurgery are discussed. …
Skewed X Inactivation And Ivf-Conceived Infants, Jennifer King, Baoli Yang, Amy Sparks, Lindsay Mains, Jeffrey Murray, Bradley Van Voorhis
Skewed X Inactivation And Ivf-Conceived Infants, Jennifer King, Baoli Yang, Amy Sparks, Lindsay Mains, Jeffrey Murray, Bradley Van Voorhis
Amy E.T. Sparks
No abstract provided.
Variations In Gestational Age At Delivery And Birth Weight In Infants Born After Assisted Reproductive Technologies Based On Maternal Infertility Diagnoses., E. Eppsteiner, B. Stegmann, Bradley Van Voorhis, J. Blaine, Amy Sparks
Variations In Gestational Age At Delivery And Birth Weight In Infants Born After Assisted Reproductive Technologies Based On Maternal Infertility Diagnoses., E. Eppsteiner, B. Stegmann, Bradley Van Voorhis, J. Blaine, Amy Sparks
Amy E.T. Sparks
No abstract provided.
Decision To Do Iui Or Ivf - Sperm Count? Reply, Bradley Van Voorhis, Amy Sparks, Craig Syrop
Decision To Do Iui Or Ivf - Sperm Count? Reply, Bradley Van Voorhis, Amy Sparks, Craig Syrop
Amy E.T. Sparks
No abstract provided.
Reducing The Risk Of Multi-Fetal Gestation By Implementation Of A Single Blastocyst Transfer Policy., Amy Sparks, G. Ryan, C. Sipe, A. Dokras, Craig Syrop, Bradley Van Voorhis
Reducing The Risk Of Multi-Fetal Gestation By Implementation Of A Single Blastocyst Transfer Policy., Amy Sparks, G. Ryan, C. Sipe, A. Dokras, Craig Syrop, Bradley Van Voorhis
Amy E.T. Sparks
No abstract provided.
Day 5 Transfers - When Are Two Blastocysts Too Many?, Amy Sparks, G. Ryan, A. Dokras, W. Davis, Craig Syrop, Bradley Van Voorhis
Day 5 Transfers - When Are Two Blastocysts Too Many?, Amy Sparks, G. Ryan, A. Dokras, W. Davis, Craig Syrop, Bradley Van Voorhis
Amy E.T. Sparks
No abstract provided.
The Efficacy And Cost-Effectiveness Of Embryo Cryopreservation Compared With Other Assisted Reproductive Techniques, B. J. Vanvoorhis, Amy Sparks, Craig Syrop, D. W. Stovall, B. D. Allen
The Efficacy And Cost-Effectiveness Of Embryo Cryopreservation Compared With Other Assisted Reproductive Techniques, B. J. Vanvoorhis, Amy Sparks, Craig Syrop, D. W. Stovall, B. D. Allen
Amy E.T. Sparks
No abstract provided.
Assisted Reproduction And Birth Defects., C. Olson, Craig Syrop, A. Dokras, G. Ryan, Amy Sparks, Bradley Van Voorhis
Assisted Reproduction And Birth Defects., C. Olson, Craig Syrop, A. Dokras, G. Ryan, Amy Sparks, Bradley Van Voorhis
Amy E.T. Sparks
No abstract provided.
The Effectiveness Of Sublingual Progesterone Administration During Cryopreserved Embryo Transfer Cycles: Results Of A Matched Follow-Up Study, D. Stovall, Amy Sparks, Bradley Van Voorhis, F. Chapler, K. Mattingly, Craig Syrop
The Effectiveness Of Sublingual Progesterone Administration During Cryopreserved Embryo Transfer Cycles: Results Of A Matched Follow-Up Study, D. Stovall, Amy Sparks, Bradley Van Voorhis, F. Chapler, K. Mattingly, Craig Syrop
Amy E.T. Sparks
No abstract provided.
Selective Early Elimination Of Luteal Support In Assisted Reproduction Cycles Using A Gonadotropin-Releasing Hormone Agonist During Ovarian Stimulation, D. Stovall, Bradley Van Voorhis, Amy Sparks, L. Adams, Craig Syrop
Selective Early Elimination Of Luteal Support In Assisted Reproduction Cycles Using A Gonadotropin-Releasing Hormone Agonist During Ovarian Stimulation, D. Stovall, Bradley Van Voorhis, Amy Sparks, L. Adams, Craig Syrop
Amy E.T. Sparks
No abstract provided.
Prognostic Factors For Pregnancy Following Intrauterine Insemination And In Vitro Fertilization, Bradley Van Voorhis, M. Barnett, Amy Sparks, Craig Syrop, A. Dokras, J. Sandlow
Prognostic Factors For Pregnancy Following Intrauterine Insemination And In Vitro Fertilization, Bradley Van Voorhis, M. Barnett, Amy Sparks, Craig Syrop, A. Dokras, J. Sandlow
Amy E.T. Sparks
No abstract provided.
In Vitro Fertilization Is Associated With An Increase In Major Birth Defects, C. Olson, K. Keppler-Noreuil, P. Romitti, W. Budelier, Ginny Ryan, Amy Sparks, Bradley Van Voorhis
In Vitro Fertilization Is Associated With An Increase In Major Birth Defects, C. Olson, K. Keppler-Noreuil, P. Romitti, W. Budelier, Ginny Ryan, Amy Sparks, Bradley Van Voorhis
Amy E.T. Sparks
OBJECTIVE: To determine the risk of major birth defects in cohorts of children conceived through IVF or through IUI as compared with naturally conceived children. DESIGN: Retrospective cohort study. SETTING: Academic medical center. PATIENT(S): Children conceived by IVF or IUI at the University of Iowa from 1989 through 2002, compared with a matched cohort of naturally conceived children. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Outcome data were obtained from Iowa state birth and fetal death certificates and from the Iowa Birth Defects Registry. RESULT(S): Ninety of 1,462 IVF-conceived children (6.2%) and 17 of 343 IUI-conceived children (5.0%) had a major birth …
Ovarian Volume May Predict Assisted Reproductive Outcomes Better Than Follicle Stimulating Hormone Concentration On Day 3, Craig Syrop, J. Dawson, K. Husman, Amy Sparks, Bradley Van Voorhis
Ovarian Volume May Predict Assisted Reproductive Outcomes Better Than Follicle Stimulating Hormone Concentration On Day 3, Craig Syrop, J. Dawson, K. Husman, Amy Sparks, Bradley Van Voorhis
Amy E.T. Sparks
No abstract provided.
Computational Models For Prediction Of Ivf/Icsi Outcomes With Surgically Retrieved Spermatozoa, M. Wald, Amy Sparks, J. Sandlow, Bradley Van Voorhis, Craig Syrop, C. Niederberger
Computational Models For Prediction Of Ivf/Icsi Outcomes With Surgically Retrieved Spermatozoa, M. Wald, Amy Sparks, J. Sandlow, Bradley Van Voorhis, Craig Syrop, C. Niederberger
Amy E.T. Sparks
IVF/intracytoplasmic sperm injection (ICSI) using surgically retrieved spermatozoa (SRS) is a key option in the treatment of severe male infertility. It was aimed to develop a computational model for the prediction of this modality's outcome. A dataset of 113 exemplars, derived from patients who underwent IVF/ICSI with SRS, was retrospectively analysed. The dataset, containing input features maternal age, sperm retrieval technique, type of spermatozoa used, type of male factor and output intrauterine pregnancy, was randomized into a modelling ('training') set of 83 and cross-validation ('test') set of 30. neUROn++, a set of C++ programs, was used to model the dataset …
Achievement Test Performance In Children Conceived By Ivf, L. Mains, M. Zimmerman, J. Blaine, B. Stegmann, Amy Sparks, T. Ansley, Bradley Van Voorhis
Achievement Test Performance In Children Conceived By Ivf, L. Mains, M. Zimmerman, J. Blaine, B. Stegmann, Amy Sparks, T. Ansley, Bradley Van Voorhis
Amy E.T. Sparks
BACKGROUND: Long-term follow-up studies of children conceived by IVF are limited. We examine academic performance on standardized tests [Iowa Tests of Basic Skills/Educational Development (ITBS/ITED)] of children conceived by IVF. METHODS: Parents of children 8-17 years of age at the onset of the study (March 2008) who were conceived by IVF at the University of Iowa Hospitals and Clinics and living in the state of Iowa were contacted by mail. Parents completed questionnaires on their child's health and education and parental education. ITBS/ITED scores from school grades 3-12 were obtained on IVF children and a group of anonymous children matched …
Oral Ovulation Induction Agents Combined With Low-Dose Gonadotropin Injections And Intrauterine Insemination: Cost- And Clinical Effectiveness, Ginny Ryan, V. Moss, W. Davis, Amy Sparks, A. Dokras, Bradley Van Voorhis
Oral Ovulation Induction Agents Combined With Low-Dose Gonadotropin Injections And Intrauterine Insemination: Cost- And Clinical Effectiveness, Ginny Ryan, V. Moss, W. Davis, Amy Sparks, A. Dokras, Bradley Van Voorhis
Amy E.T. Sparks
OBJECTIVE: To compare the efficacy and cost-effectiveness of different induction protocols involving gonadotropins with intrauterine insemination (IUI). STUDY DESIGN: We performed a retrospective chart review of 648 IUI cycles. Some patients had gonadotropin injections alone before human chorionic gonadotropin (hCG) and IUI (human menopausal gonadotropin protocol); others were given oral medications, then gonadotropins before hCG and IUI (combination protocol). Outcomes included pregnancy rates, multiple birth rates, endometrial thickness, number of ovarian follicles, injection days, ampules of gonadotropins and cost. RESULTS: The combination protocol was more cost-effective. In first cycles, pregnancy rates, multiple birth rates, number of large follicles produced and …
Tubal Versus Uterine Transfer Of Cryopreserved Embryos - A Prospective Randomized Trial, B. J. Vanvoorhis, D. H. Chestnut, Craig Syrop, Amy Sparks, R. D. Vincent, F. K. Chapler
Tubal Versus Uterine Transfer Of Cryopreserved Embryos - A Prospective Randomized Trial, B. J. Vanvoorhis, D. H. Chestnut, Craig Syrop, Amy Sparks, R. D. Vincent, F. K. Chapler
Amy E.T. Sparks
No abstract provided.
Anovulation May Be A Risk Factor For Major Birth Defects In Children Born After Infertility Treatment., Bradley Van Voorhis, Amy Sparks, Craig Syrop, C. Sipe, G. Ryan, A. Dokras
Anovulation May Be A Risk Factor For Major Birth Defects In Children Born After Infertility Treatment., Bradley Van Voorhis, Amy Sparks, Craig Syrop, C. Sipe, G. Ryan, A. Dokras
Amy E.T. Sparks
No abstract provided.
Cost-Effectiveness Of Infertility Treatments: A Cohort Study, Bradley Van Voorhis, Amy Sparks, B. Allen, D. Stovall, Craig Syrop, F. Chapler
Cost-Effectiveness Of Infertility Treatments: A Cohort Study, Bradley Van Voorhis, Amy Sparks, B. Allen, D. Stovall, Craig Syrop, F. Chapler
Amy E.T. Sparks
OBJECTIVE: To determine the cost-effectiveness of infertility treatments. DESIGN: Retrospective cohort study. SETTING: Academic medical center infertility practice. PATIENT(S): All patients treated for infertility in a 1-year time span. INTERVENTION(S): Intrauterine inseminations, clomiphene citrate and IUI (CC-IUI), hMG and IUI (hMG-IUI), assisted reproductive techniques (ART), and neosalpingostomy by laparotomy. MAIN OUTCOME MEASURE(S): All medical charges and pregnancy outcomes associated with the treatments were obtained. Cost-effectiveness ratios defined as cost per delivery were determined for each procedure. The effects of a woman's age and the number of spermatozoa inseminated on cost-effectiveness of the procedures was also determined. RESULT(S): Intrauterine inseminations, CC-IUI, …
The Cost Of Infertility Evaluation And Therapy: Findings Of A Self-Insured University Healthcare Plan., D. Stovall, B. Allen, Amy Sparks, Craig Syrop, R. Saunders, Bradley Van Voorhis
The Cost Of Infertility Evaluation And Therapy: Findings Of A Self-Insured University Healthcare Plan., D. Stovall, B. Allen, Amy Sparks, Craig Syrop, R. Saunders, Bradley Van Voorhis
Amy E.T. Sparks
OBJECTIVE: To assess the total costs of infertility coverage, determine the proportion of healthcare costs related to infertility, compare infertility costs to those of other diseases, and calculate a per member per month cost of an infertility benefit. DESIGN: Historical prospective analysis. SETTING: A university-based, self-insured, fee-for-service healthcare plan. PATIENT(S): Healthcare policy members from January 1993 through December 1995. INTERVENTION(S): General and infertility-specific healthcare that included diagnostic tests for infertility, induction of ovulation, artificial insemination, donor gametes, in vitro fertilization, gamete intrafallopian transfer, zygote intrafallopian transfer, microsurgical epididymal sperm aspiration, embryo cryopreservation, and frozen embryo transfer. MAIN OUTCOME MEASURE(S): Healthcare …
Hyperbaric Oxygen And Ovarian Follicular Stimulation For In Vitro Fertilization: A Pilot Study, Bradley Van Voorhis, J. Greensmith, A. Dokras, Amy Sparks, S. Simmons, Craig Syrop
Hyperbaric Oxygen And Ovarian Follicular Stimulation For In Vitro Fertilization: A Pilot Study, Bradley Van Voorhis, J. Greensmith, A. Dokras, Amy Sparks, S. Simmons, Craig Syrop
Amy E.T. Sparks
No abstract provided.
Effect Of The Total Motile Sperm Count On The Efficacy And Cost-Effectiveness Of Intrauterine Insemination And In Vitro Fertilization, Bradley Van Voorhis, M. Barnett, Amy Sparks, Craig Syrop, G. Rosenthal, J. Dawson
Effect Of The Total Motile Sperm Count On The Efficacy And Cost-Effectiveness Of Intrauterine Insemination And In Vitro Fertilization, Bradley Van Voorhis, M. Barnett, Amy Sparks, Craig Syrop, G. Rosenthal, J. Dawson
Amy E.T. Sparks
No abstract provided.