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Articles 181 - 210 of 2525
Full-Text Articles in Medicine and Health Sciences
Acute Placental Inflammation And Growth Outcomes In Preterm Infants, Emily Gunawan
Acute Placental Inflammation And Growth Outcomes In Preterm Infants, Emily Gunawan
All ETDs from UAB
Background. Acute placental inflammation (API) has been associated with various adverse outcomes in preterm infants. However, little is known about how API affects their body composition and growth outcomes. This study aims to examine the association between API and growth outcomes in preterm infants. Methods. We conducted a retrospective cohort study of mother-infant dyads born < 326/7 weeks of gestation with fat mass (FM) accretion measured using air displacement plethysmography at term-equivalent age. API severity including maternal inflammatory response (MIR) and fetal inflammatory response (FIR) was staged according to criteria by Society for Pediatric Pathology based on placental pathology reports. We examined the differences in characteristics of mother-infant dyads by API severity using ANOVA or the Kruskall-Wallis test. The association between API severity and growth outcomes was analyzed using linear regression models and adjusted for statistically significant confounders. Mediation analyses were used to study the direct and indirect association of API and growth outcomes via gestational age. Results. Among 375 mother-infant dyads analyzed, 104 (28%) dyads had MIR. FIR was found in 82% of dyads with MIR. Adjusted models indicated that API severity progression was positively associated with FM accretion. Gestational age partially (49%) iv mediated the association between API severity and FM z score (indirect effect: b=0.12, 95% CI: 0.05-0.19; direct effect: b=0.12, 95% CI: 0.01-0.25). Conclusions. API severity is associated with growth outcomes and helps to accurately predict body composition in preterm infants.
Social Vulnerability And Racial Disparities In Overall Survival Among Endometrial Cancer Patients, Alfonsus Adrian Hadikusumo Harsono
Social Vulnerability And Racial Disparities In Overall Survival Among Endometrial Cancer Patients, Alfonsus Adrian Hadikusumo Harsono
All ETDs from UAB
Introduction. Social vulnerability (SV) refers to potential negative effects on communities caused by external stresses on human health. The CDC/ATSDR Social Vulnerability Index (SVI) scores communities on 15 social indicators in 4 themes: (1) socioeconomic status (SES), (2) household composition and disability, (3) minority status and language, and (4) housing type and transportation. An overall score ranging from 0 (least vulnerable) to 1 (most vulnerable) is calculated to estimate vulnerability. We investigated whether SV as measured by the SVI can explain why black endometrial cancer (EC) patients survive less well than do white EC patients. Methods. We studied the survival …
Failure Modes Of Different Zirconia Crown Heights And Materials On Titanium Base Abutments, Aikaterini Anastasaki
Failure Modes Of Different Zirconia Crown Heights And Materials On Titanium Base Abutments, Aikaterini Anastasaki
All ETDs from UAB
Statement of the Problem: The existing scientific literature lacks comprehensive information regarding the influence of zirconia crown height on debonding and fracture occurrences between zirconia crowns and titanium base abutments. Additionally, there is a lack of comparative studies evaluating different zirconia materials as restorative options for screw-retained restorations. Purpose: The purpose of this study was to assess the failure modes of the zirconia crown/titanium implant abutment complex by investigating the impact of increasing zirconia crown heights and different zirconia materials. Materials and Methods: The experimental design encompassed six groups, each consisting of 10 specimens. Group 1 included 10 non-anatomical crowns …
The Role Of Runx2 And Sp7 In Ameloblast Differentiation And Postnasal Enamel Synthesis, Reem Alhefdhi
The Role Of Runx2 And Sp7 In Ameloblast Differentiation And Postnasal Enamel Synthesis, Reem Alhefdhi
All ETDs from UAB
In mammals, the mineralized tissues include bone, dentin, enamel, and cementum. Runx2 and its downstream target Sp7 are essential transcription factors for the osteoblast differentiation and formation of bone tissue. However, transcription factors that regulate ameloblast differentiation and enamel secretion are less understood. To uncover the role of Runx2 and Sp7 in ameloblasts differentiation and enamel synthesis, we established a colony of Runx2 and Sp7 floxed mice. Both genes were deleted specifically in ameloblasts using K14-Cre transgenic mice. The successful deletion of Runx2 and Sp7 genes in the epithelium, including ameloblasts, was confirmed using Td-Tomato and GFP reporter, respectively. Histological …
Pharmacologic Proteasome Activators Ameliorate Alzheimer's-Like Pathology In Ad Fly Models, Mehar Bano
Pharmacologic Proteasome Activators Ameliorate Alzheimer's-Like Pathology In Ad Fly Models, Mehar Bano
All ETDs from UAB
The proteasome is a large multi-subunit protease responsible for the degradation and removal of oxidized, misfolded, and polyubiquitinated proteins. The proteasome plays a critical role in nervous system processes. This includes the maintenance of cellular homeostasis in neurons (1). It also includes synaptic efficacy and plasticity as well as protein turnover, presynaptic vesicle transport, and neuronal protesostasis. Proteasome function is impaired as a consequence of aging, which is aggravated by conditions like Alzheimer's Disease and Related-Dementias (AD, ADRD) (2). According to earlier work from our lab the proteasome is critical to how quickly AD progresses. In Drosophila, human cells, and …
Role Of Dpy30 In The Epigenetic Regulation Of Odontoblast Differentiation In Vitro, Namrata Landge Rana
Role Of Dpy30 In The Epigenetic Regulation Of Odontoblast Differentiation In Vitro, Namrata Landge Rana
All ETDs from UAB
Purpose: Dentin is produced from odontoblasts, derived from human Dental Pulp Cells (hDPCs), which are essential for dentin formation, remodeling, and mineral hemostasis. Epigenetic mechanisms are believed to be involved in odontoblast differentiation and function, and H3K4 methylation is associated with gene activation which is fundamental to histone-based epigenetics. The SET1/MLL complexes are mammals' major histone H3K4 methylation enzymes. DPY30 is a core subunit of SET1/MII complexes, mammalian's major histone H3K4 methyltransferases. It plays an important role in regulating fundamental processes including the determination of cell lineage, growth, and differentiation. Thus, histone-based epigenetic mechanisms are involved in odontoblast differentiation and …
Molecular Determinants Of Retroviral Gag Targeting To The Plasma Membrane For Assembly, Dominik Herrmann
Molecular Determinants Of Retroviral Gag Targeting To The Plasma Membrane For Assembly, Dominik Herrmann
All ETDs from UAB
Human T-cell leukemia virus 1 (HTLV-1) was the first oncogenic human retrovirus to be discovered. Several serious diseases have been linked to HTLV-1 infection, such as Adult T-cell leukemia (ATL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). Between 10-20 million people are infected with HTLV-1 making it a major cause of morbidity and mortality worldwide. A comprehensive understanding of the factors that govern retroviral replication precludes the development of efficient antiretroviral therapies (ARTs). In the example of HIV-1, atomic level structural data was paramount to developing and improving upon many of the ARTs used today, underscoring the need for structure …
Early Life Stress And Endothelin Receptor Type A: Separate Roles In Mediating Colitis, Rachel Q. Muir
Early Life Stress And Endothelin Receptor Type A: Separate Roles In Mediating Colitis, Rachel Q. Muir
All ETDs from UAB
Inflammatory bowel disease (IBD) results from the interplay of genetic susceptibility, environmental influences, the microbiota, and aberrant immune responses. Despite the fact that over 200 genetic susceptibility loci have been identified, the genetic contribution to disease onset is believed to be less than 50%. Environmental factors have arisen as key drivers of disease. Early life stress (ELS) is an understudied environmental trigger linked to IBD susceptibility. Utilizing 2 separate models of ELS, we show that ELS results in diminished colonic corticosterone and prolonged intestinal inflammation upon colitogenic insult. ELS-exposed animals consistently demonstrated high levels of colonic Tnf, concurrently with decreased …
Sex-Stratified Genetic Analysis Of Gout And Comorbidities, Nicholas Andrew Sumpter
Sex-Stratified Genetic Analysis Of Gout And Comorbidities, Nicholas Andrew Sumpter
All ETDs from UAB
Gout is a common inflammatory arthritis that is increasing in prevalence globally. It has clear sex differences, being more common among men, though comorbidities appear to be more common among women. It also varies in prevalence between populations, driven by a combination of genetic and socioeconomic factors. Genetic studies have identified gout-associated genetic variants, several of which are shared between different populations. Here, I combined gout-associated genetic variants into a gout polygenic risk score. This score was then used to elucidate the genetic underpinning of gout severity and presence of comorbidities, comparing its effects in different sexes and populations. I …
The Influence Of A Low Glycemic Load Diet On Appetite In Women With Pcos, Sarah Et Hoover
The Influence Of A Low Glycemic Load Diet On Appetite In Women With Pcos, Sarah Et Hoover
All ETDs from UAB
Dysregulated appetite may contribute to weight gain and high prevalence of comorbid obesity in women with polycystic ovary syndrome (PCOS), yet dietary recommendations to promote satiety and facilitate weight maintenance in this population remain scarce. The objective of this dissertation was to determine if women with PCOS have alterations in appetite-regulating hormones that can be manipulated by low glycemic load diet habituation to improve satiety. This was tested by secondary analyses of two randomized controlled dietary intervention trials in women with and without PCOS. First, we explored differences in women with and without PCOS during a standardized liquid meal test …
Aberrant Signal Transduction Of Neuronal Injury: Trauma And Toxicology, Alan Umfress
Aberrant Signal Transduction Of Neuronal Injury: Trauma And Toxicology, Alan Umfress
All ETDs from UAB
Neurological injuries occur in epidemic proportions worldwide. Neuronal injuries are events resulting in damage to the central nervous system (CNS) that impair neurological function. Subsequent impairments in neuronal function can be rapid, existing immediately after injury, or progressive and chronic impairments that persist for the lifetime of the survivor. CNS injury constitutes a broad class of environmental and pathophysiological insults ranging from blunt-force trauma to the brain or spinal cord, to acute ischemic and hemorrhagic strokes, and insults resultant from neurotoxic agents. While divergent in initial cause, many of these insults share underlying pathophysiological outcomes including excitotoxic cell signaling, neuroinflammation, …
Mechanisms Of Simulated-Spinal Manipulative Therapy In Animal Models Of Low Back Pain, Carla Rigo Lima
Mechanisms Of Simulated-Spinal Manipulative Therapy In Animal Models Of Low Back Pain, Carla Rigo Lima
All ETDs from UAB
Low back pain (LBP), a condition characterized by pain experienced between the 12th rib margin and gluteal folds, is a prevalent health problem that affects an ever-increasing population worldwide. First-line treatment for LBP often involves non-pharmacological approaches, including spinal manipulative therapy (SMT), which has demonstrated mild-to-moderate clinical efficacy. However, despite its therapeutic benefits, the physiological mechanisms underlying the analgesic effects of SMT in LBP are still not well understood. Recent evidence suggests that sensitization of peripheral and central nervous system structures contribute to the progression and maintenance of LBP with inflammatory cytokines, reactive glial cells, and/or aberrant muscle spindle activity …
Strategies For Her2 Targeted Pet Imaging, Maxwell Adams Ducharme
Strategies For Her2 Targeted Pet Imaging, Maxwell Adams Ducharme
All ETDs from UAB
Breast cancer is one of the most common and deadly cancers diagnosed in women each year. The HER2-positive subtype of breast cancer is associated with poor prognosis and lower progression-free survival. Early identification of HER2 expression is extremely important for the effective treatment of the disease. Current methods to diagnose HER2-positive breast cancer involve invasive biopsies to semi-quantitatively determine the amount of HER2 expression. However, many lesions are often unavailable for biopsy due to their location and there may be variable HER2 expression between the primary tumor and metastasis. Positron emission tomography (PET) can give a full-body, non-invasive evaluation of …
Investigating Regulatory Mechanisms Of Transcription By Rna Polymerase I, Abigail Kate Huffines
Investigating Regulatory Mechanisms Of Transcription By Rna Polymerase I, Abigail Kate Huffines
All ETDs from UAB
There are at least three eukaryotic RNA polymerases (Pols), Pols I, II, and III. These Pols are essential for transcription, where RNA is synthesized from various DNA templates. While transcription has been well-studied for decades, there are still many questions that remain unanswered about how this process is regulated for each of the three Pols. Transcription is highly regulated and complex, therefore, many different mechanisms exist to tightly control it in the cell. Some of these mechanisms include regulation by transcription factors and co-transcriptional RNA processing. While these regulatory mechanisms are of great interest, they have not yet been fully …
Biochemical Characterization Of Rna Polymerases I, Ii, And Iii And Its Therapeutic Implications, Ruth Qian Jacobs
Biochemical Characterization Of Rna Polymerases I, Ii, And Iii And Its Therapeutic Implications, Ruth Qian Jacobs
All ETDs from UAB
In contrast to Bacteria and Archaea that express a single DNA-dependent RNA polymerase (RNAP), eukaryotes express at least three structurally distinct, nuclear, DNA-dependent RNA polymerases (Pols I, II, and III) that are responsible for synthesizing all the genome-encoded RNA required by the cell. Despite the discovery of the Pols over 50 years ago, there remains a knowledge gap concerning their enzymatic properties. Over the course of evolution, we know that Pols I, II, and III have diverged in structure and function. They share a 10-subunit core and are each responsible for transcribing unique genetic loci. What remains to be understood …
Neural-Glial-Vascular Interactions In Human Outer Retina, Deepayan Kar
Neural-Glial-Vascular Interactions In Human Outer Retina, Deepayan Kar
All ETDs from UAB
The outer retinal metabolic ecosystem is a complex interplay among photoreceptors, RPE and blood supply from the retinal and choroidal microcirculation. Breakdown of any component of this ecosystem has detrimental effects and can lead to cellular dysfunction. For example, in age-related macular degeneration a major cause of vision loss in older adults, breakdown of this metabolic unit has severe structural and functional implications. Thus, every feature and component of this ecosystem seems to be optimized to protect non-replicating, terminally differentiated cells from being damaged. Remarkably, much of the cellular and subcellular organization of this system is available for observation in …
The Association Of Availability And Accessibility Of Federally Qualified Health Centers On Hospitals' Reported Charity Care, Philip Cendoma
The Association Of Availability And Accessibility Of Federally Qualified Health Centers On Hospitals' Reported Charity Care, Philip Cendoma
All ETDs from UAB
Hospitals are facing financially challenging times. Each year, billions of dollars are spent by hospitals to provide care to patients that, ultimately, will go unreimbursed. How to effectively provide accessible and affordable health care to the uninsured population continues to be a topic of discussion for policymakers, healthcare administrators, as well as healthcare-based consortiums, and consultant. The cost of charity care consists largely of the care provided to the uninsured population. Federally Qualified Health Centers (FQHCs) play an important role in providing primary care to the uninsured population, regardless of the patient’s ability to pay. Based on the 5 A’s …
Neutrophil Heterogeneity And Alternative Granulopoiesis In Chronic Inflammatory Conditions, Ashley N. Connelly
Neutrophil Heterogeneity And Alternative Granulopoiesis In Chronic Inflammatory Conditions, Ashley N. Connelly
All ETDs from UAB
Neutrophils, the most abundant type of circulating leukocyte, represent a heterogeneous population with distinct roles in immune regulation and disease pathogenesis. A major obstacle to our understanding of neutrophil biology is that neutrophils are readily activated during preparation. The lack of standardized methodology for neutrophil characterization makes the comparison of results across studies challenging. Here we provide a careful comparison of eight characterization methods and present a novel, optimized protocol for the characterization of whole blood neutrophils minimizing activationinduced phenotypic alterations during processing. Despite successful virological control, HIV-1-infected individuals maintain an increased risk of life-threatening comorbidities including liver, cardiovascular, and …
Impact Of Arthroplasty Surgery On The Local Immune Composition Of The Knee Joint And Implications For The Periprosthetic Joint Infection, Kyle H. Cichos
Impact Of Arthroplasty Surgery On The Local Immune Composition Of The Knee Joint And Implications For The Periprosthetic Joint Infection, Kyle H. Cichos
All ETDs from UAB
The overall risk of infection after total knee arthroplasty (TKA) has not improved over the past 20 years, remaining 10-40 times greater than the risk of infection of a native knee. Despite extensive research into periprosthetic joint infection (PJI), little is known about the synovial fluid immune homeostasis of the native knee joint and how TKA surgery itself impacts the local immune composition. While many postulate a role for cartilage in maintaining this immune homeostasis, the exact method in which it contributes remains elusive. Therefore, in this dissertation I have investigated the synovial fluid changes occurring in the knee joint …
Differential Recruitment Of Bone Marrow-Derived Cells Into The Injured Retina, Bright Asare-Bediako
Differential Recruitment Of Bone Marrow-Derived Cells Into The Injured Retina, Bright Asare-Bediako
All ETDs from UAB
The hematopoietic system, which resides in the bone marrow in adults, maintains the constant turnover of blood cells in the circulatory system and supplies inflammatory/vascular reparative cells to the retina. Chronic metabolic diseases disrupt hematopoietic homeostasis, suppressing the generation of bone marrow-derived reparative cells in favor of pro-inflammatory cells. While much research has been done on development and disease-associated changes in hematopoiesis in the long bones and how mobilization to the retina is affected, the calvarium's hematopoiesis is underexplored. This dissertation investigated hematopoiesis in postnatal development and in disease, comparing calvarium hematopoiesis to that of long bones. The findings showed …
Contributions Of Off-Season Training And Food Security Status On Body Composition And Performance In Collegiate Football Players, Kathryn Lee Stowers
Contributions Of Off-Season Training And Food Security Status On Body Composition And Performance In Collegiate Football Players, Kathryn Lee Stowers
All ETDs from UAB
Body composition measurements are collected periodically in the collegiate athletic setting to evaluate health and predict athletic performance of individual athletes. However, the effects of remote training and food insecurity on body composition have yet to be fully investigated in this population. The purpose of this research was to evaluate the influence of remote training and food security status on body composition and performance changes during off-season training. Aims 1 and 2 focus specifically on how factors affect body composition changes in collegiate football players during off-season training. Data were collected from routine body composition testing and food security screening …
Induction Of Antibiotic Activity Against Methicillin-Resistant Staphylococcus Aureus In Small Molecules Through Zinc Activation, Rachel Michaela Andrews
Induction Of Antibiotic Activity Against Methicillin-Resistant Staphylococcus Aureus In Small Molecules Through Zinc Activation, Rachel Michaela Andrews
All ETDs from UAB
Methicillin-resistant Staphylococcus aureus (MRSA) is a serious human pathogen with a staggering potential for multi-drug resistance. Because of this, the Centers for Disease Control and Prevention and the World Health Organization monitor the spread of MRSA and encourage antibiotic development efforts targeting this pathogen. Despite this, few antibiotics have been developed and brought to market in recent decades. To continue treating infections caused by this organism, we must identify novel antibiotic molecules with different mechanisms of action from known antibiotics. Bacterial copper-dependent inhibitors (CDIs), molecules that become antibacterial in the presence of copper (Cu), have been studied as a novel …
Comparing Volumetric Wear Of Lithium Disilicate Against Different Ceramics And Enamel Antagonist An In-Vitro Study, Krisha Shah
Comparing Volumetric Wear Of Lithium Disilicate Against Different Ceramics And Enamel Antagonist An In-Vitro Study, Krisha Shah
All ETDs from UAB
Background: In patients with restored dentitions, it is possible for crowns on opposing teeth to gradually wear each other through chewing and bruxism. Therefore, the wear of restorative materials used for dental crowns is an important mechanical property for their long-term clinical success. Lithium disilicate is a widely used dental ceramic due to its strength, machinability, and translucency. Due to the rising use of ceramic restorations, a comparison of the wear resistance of lithium disilicate against different ceramic crown materials is useful for the clinician when selecting a crown material to oppose an existing lithium disilicate crown. Objective: To compare …
Chronic Hiv Infection Influences The Immune Response To Sars-Cov-2, Skye Opsteen
Chronic Hiv Infection Influences The Immune Response To Sars-Cov-2, Skye Opsteen
All ETDs from UAB
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused global morbidity and mortality since late 2019. Many infections result in self-limited disease and recovery in 1-2 weeks. However, a subset of individuals experience more severe illness, associated with hospitalization, ventilation, and potential mortality. HIV infection is a proposed risk factor for more severe illness due to people living with HIV (PLWH) experiencing chronic immune activation and inflammation despite effective antiretroviral therapy. While there is supporting evidence showing worsened clinical outcomes in PLWH experiencing acute COVID-19, the immune response driving these outcomes is less explored. We analyzed markers of immune activation …
Diagnostic Outcomes Of Digital Images For Comprehensive Examination In Pediatric Dentistry: An Intraexaminer Agreement Assessment, Maria Fernanda Montoya
Diagnostic Outcomes Of Digital Images For Comprehensive Examination In Pediatric Dentistry: An Intraexaminer Agreement Assessment, Maria Fernanda Montoya
All ETDs from UAB
Purpose: To Assess intra-examiner diagnoses obtained via traditional oral clinical examination (TCE) versus digital oral examination (DOE) completed from digital video images of pediatric patients. Methods: Fifty pediatric patients 5 to 10 years of age, who attend the Pediatric Dentistry Clinic at the University of Alabama at Birmingham (UAB) for initial consultations or regular visits were included in this study. Individual oral comprehensive examinations were done by five second-year pediatric dentistry residents. A trained dental hygienist recorded a full mouth intraoral video for each patient via MouthWatch intraoral camera and stored using existing Information and Communication Technology (ICT) infrastructure. After …
Effect Of Different Supporting Die Materials And Crown Thicknesses On The Fracture Load Of Monolithic 3y-Tzp Zirconia And Lithium Disilicate Crowns, Akram Mohamed Mohamed Gad Sayed Ahmed
Effect Of Different Supporting Die Materials And Crown Thicknesses On The Fracture Load Of Monolithic 3y-Tzp Zirconia And Lithium Disilicate Crowns, Akram Mohamed Mohamed Gad Sayed Ahmed
All ETDs from UAB
Background: Conventionally, the strength of dental materials used for fixed restorations is measured using specimens of simplified geometry (i.e bars or discs). There is value in measuring the strength of these materials in their anatomic geometry (i.e crowns) under clinically relevant loading conditions. One advantage of performing the so-called crown fracture test is that the material may benefit from its ability to be strengthened by its bond to a tooth-mimicking die. When performing a crown fracture test, the ideal die material is natural tooth structure. However, the variability in natural tooth anatomy and microstructure makes the use of a standardized, …
Uncovering The Role Of Spt5 In Rna Polymerase I Transcription Through Targeted Protein Degradation Via The Auxin Inducible Degron System In Saccharomyces Cerevisiae, Nathan Bellis
All ETDs from UAB
RNA Polymerases are the molecular machines responsible for the synthesis of RNA from the DNA template. The presence of these machines is an absolute requirement for the function and replication of all cellular organisms. In eukaryotic organisms, there are a minimum of three RNA polymerases (Pols I, II, II). Despite shared subunits and homology, these three protein complexes are functionally distinct, with many unique sub-units and additional trans-acting factors. Pol I is responsible for the synthesis of three of the four ribosomal RNA species which is the first and rate limiting step of ribosome biogenesis. Pol I synthesizes the majority …
Characterizing A Unique Oprm1 Expressing Neuronal Population In The Rat Nucleus Accumbens, Emma Andraka
Characterizing A Unique Oprm1 Expressing Neuronal Population In The Rat Nucleus Accumbens, Emma Andraka
All ETDs from UAB
Opioid-related overdose deaths have increased drastically in the past three decades, and especially since the beginning of the COVID-19 pandemic, due to the addictive, analgesic, and euphoric properties of the drugs. To produce these effects, opioids bind to the mu opioid receptor (MOR) in GABAergic neurons. The MOR is encoded by the Oprm1 gene and is expressed in multiple brain regions that regulate reward and motivation, such as the nucleus accumbens (NAc). Previous studies of Oprm1 knockdown in medium spiny neurons (MSNs) of the mouse NAc have shown that these neuronal populations are involved in reinforcing reward-context pairing as well …
Short Root Anomaly: Prevalence, Genetics, And Its Effect In Orthodontic Treatment, Lauren Sharp
Short Root Anomaly: Prevalence, Genetics, And Its Effect In Orthodontic Treatment, Lauren Sharp
All ETDs from UAB
Short root anomaly (SRA) is a poorly understood developmental defect of root formation. Patients with this condition have short roots with rounded apexes and significantly reduced root to crown (R/C) ratios1, which can compromise dental care and may increase the risk of root resorption during tooth movement. SRA prevalence ranges from 1-10% but has not been studied in many ethnic populations. Furthermore, its genetic basis is undetermined. Our goals were to determine the prevalence of SRA among various ethnicities, identify genetic variations contributing to its phenotype, and evaluate how SRA can affect the outcome of orthodontic treatment. This study found …
Nasal Septum Deviation In Patients With Or Without Impacted Canines, Naurine Shah
Nasal Septum Deviation In Patients With Or Without Impacted Canines, Naurine Shah
All ETDs from UAB
There has been a recent rise in interest for studying the relationship between orthodontic treatment and the airway. Most studies have focused on measuring the oropharyngeal airway and how it is affected by growth with or without orthodontic treatment. The Nasal Septum, a midline structure is an integral part of the anatomy of the nasopharynx. Nasal Septum Deviations (NSD) can be caused by mechanical injuries, nasal polyps, neoplasia, infections, genetic influences as well as congenital malformations. The proximity of the septum can be correlated to changes in the housing of dentition in the naso maxillary complex. Objective: We aim to …