Medicine and Health Sciences Commons^™

Intracranial Pressure Is A Better Predictor Of Mortalitythan Cerebral Perfusion Pressure, Ronald J. Markert, Jonathan M. Saxe, Cathryn L. Chadwick

Internal Medicine Faculty Publications

Objective: To evaluate whether elevated intracranial pressure (ICP) or depressed cerebral perfusion pressure (CPP) is a better predictor of intracranial compartment syndrome and long-term functional outcomes in blunt traumatic brain injury.

Methods: This was a retrospective evaluation of data collected on 203 patients with blunt traumatic brain injury who were admitted to Miami Valley Hospital, a Level I trauma center, over a 2 years period, whose initial hospital management required an intracranial pressure monitor. Serial measurements of ICP and CPP were recorded during the patients’ hospital stay. These patients were then evaluated at 3,6,12 and 24 months post-injury to assess …

Evidence-Based Hazmat Medical Surveillance, Michael D. Jacobson

Master of Public Health Program Student Publications

Background: Hazardous materials (HAZMAT) teams are tasked with neutralizing substances that pose a dire threat to human health. As a result, communities invest substantially in medical surveillance to protect first responders. Yet, little is known as to the actual exposures, consequent injuries, and cost-effectiveness of medical surveillance.

Objective: The purposes of this study were: 1) Determine actual HAZMAT threats. 2) In light of these threats, evaluate current regulatory requirements, recommendations and practices for their basis in evidence.

Methods: National HAZMAT data was analyzed for trends and compared with local response records from 2008 through 2011. Regulations applicable to medical surveillance …

Rights Of Ohio Mothers: Best Practices For The Pediatric Patient With A Life-Threatening Illness, Kelly Peekstok

Master of Public Health Program Student Publications

The purpose of this paper is to evaluate and review current best practices with regards to a minor’s refusal of life-sustaining medical treatment. The policies of other developed countries and states within the United States serve as a guide for developing evidence-based guidelines for Ohio healthcare professionals. Four specific cases were identified and then analyzed. The results showed that in three of the four cases, the wishes of the minor were followed. While each case contains its own set of complexities, creating a developmental guideline for healthcare organizations will ensure protection of the minor’s capacity to make autonomous decisions.

The Efficacy Of Abstinence Only Education, Jennie Watt Mcadams

Master of Public Health Program Student Publications

Chlamydia, Gonorrhea and unplanned teen pregnancies cost the United States billions of dollars every year in various forms of government aid. Why are the numbers of teenage incidences of these health indicators higher than almost every other industrialized nation? Why are the youth in the United States so far behind their peers in sexual health? This paper proposes that one cause is that government funding goes to abstinence only education curriculum which is taught in many schools across the nation. These curricula many times do not teach youth about sexual protection or health and other times contain false information. If …

Chronic Disease Prevalence Of A Refugee Population In Dayton, Oh, Sandeep Palakodeti

Master of Public Health Program Student Publications

Introduction: This study aimed to understand the chronic disease burden of anemia, cancer, diabetes mellitus, hypertension, overweight/obesity, stroke, and tobacco use in the domestic as well as a refugee population. It also aimed to examine the current literature on appropriate screening for those conditions.

Methods: 348 refugee screening intake exams from Public Health - Dayton & Montgomery County were analyzed for presence of the conditions stated. Screening intake recommendations from the CDC, the Minnesota Public Health Department, the Canadian Collaboration for Immigrant and Refugee Health, and the Ohio Department of Job and Family Services were examined and compared in order …

Analysis Of An Improved Cook Stove Intervention In Rural Guatemala, Chad Graven

Master of Public Health Program Student Publications

An estimated three billion people cook and heat their homes using open fires and nearly two million people die prematurely from illness attributable to indoor air pollution from solid fuel use. According to the World Health Organization, “every year, indoor air pollution is responsible for the death of 1.6 million people...one death every twenty seconds.” Various international groups, government initiatives, and communities have attempted to improve this indoor air pollution problem around the world by implementing various improved cook stove models. In July, 2011, Partners In Health (PIH) and Equipo Técnico de Educación en Salud Comunitaria (ETESC) co-directed the delivery …

Walkability At Wright State University, Lan H. Nguyen

Master of Public Health Program Student Publications

The purpose of this study was to examine walkability at Wright State University (WSU), Dayton Ohio using the Postsecondary Education Campus Walkability/Bikeability Semantic-Differential Assessment Instrument. Safety, path quality, and path temperature comfort were the categories of criteria assessed. A total of 66 path segments were assessed on main campus, 50 were assessed during the day and 16 were assessed during the night. The average walkability score was 84.9% for day assessed segments and 82.1% for night assessed segments. Path segments received an overall average grade of B. The findings in this study suggest that the WSU campus is a walkable …

Implementation Of The Sbar Checklist To Improve Patient Safety In The United States Air Force Aeromedical Evacuation, Karey M. Dufour

Nursing and Health Masters Publications

Inadequate or absent communication resulting in patient safety is an increasing problem in United States Air Force (USAF) aeromedical evacuation (AE). In 2010, 1,694 incident reports were filed. The lack of handoff communication was the second highest category affecting patient safety. Currently, there is no standardized patient handoff process in USAF AE. This evidence-based practice project is designed to answer the following question: In AF flight nurses transporting patients in the AE system, does the use of a standardized patient handoff checklist (using SBAR [situation-background-assessment-recommendation/request]), compared to current patient handoff practices, affect patient safety as measured by incident reports over …

Rose Melnick Medical Museum: Past, Present, And Future, Cassie Nespor

Annual Conference Presentations, Papers, and Posters

Dr. John C. Melnick was interested in local medical history; as a result, he began collecting medical artifacts in 1972. He wanted to create a museum that would cultivate an interest in medicine and promote medical history. His collection of artifacts came to Youngstown State University in 1997, and the museum opened in 2001

Maturation Of The Carotid Body Oxygen-Sensor During Rat Development, Julia Paulet

Browse all Theses and Dissertations

Carotid bodies (CB) are paired, oxygen-sensing organs located in the bifurcation of the carotid artery that act as peripheral chemoreceptors in the detection of hypoxic, hypercapnic and acidotic levels in the arterial blood. CBs respond to these fluctuations in blood gases by initiating firing of the carotid sinus nerve. This ultimately results in the appropriate ventilatory change to restore blood gases to their physiological levels. Studies have shown that the hypoxic response of the carotid body in juvenile mammals is low, but as maturation occurs this response is strengthened and clearly exhibited in adults. One theory suggests mitochondria play a …

Effects Of Elevated Glucocorticoid Levels On Dentate Gyrus Development, Zachary Dale Vallandingham

Browse all Theses and Dissertations

Exogenous glucocorticoids are commonly used in modern medications and animal studies examining the effects of glucocorticoids on the developing brain report inconsistent results. Recent reports have questioned the reliability of available drug delivery methods in mice (Herrmann et al., 2009). In our laboratory, variable behavioral results using trace eyeblink conditioning (EBC) suggest that we may be having similar problems delivering glucoroticoids to developing rat pups (Claflin et al., 2005, 2011). Subcutaneous pellets and osmotic minipumps resulted in impaired learning during trace eyeblink conditioning whereas subcutaneous injection of corticosterone (CORT) resulted in facilitation of learning on the same task. One of …

Electrical Brain Stimulation And Depressive-Like Behavior In Guinea Pigs, Nadia Kardegar

Browse all Theses and Dissertations

Maternal separation in guinea pigs produces a biphasic response consisting of an active behavior phase (vocalizations and locomotor activity) followed by a phase of passive depressive-like behavior (crouched stance, piloerection, and eye closure). The mechanism for the transition from the active to the passive phase is unknown. One suggestion is that continual activity of neural circuitry producing active behavior eventually leads to the expression of passive behaviors. The purpose of this study was to test this possibility. Guinea pigs were assigned to experimental and control groups. The experimental group received daily stimulation of the bed nucleus stria terminalis (BNST) to …

Influence Of Daily Electrical Stimulation Of Periaqueductal Grey On Vocalization And Depressive-Like Behavior During Separation In Guinea Pigs, Jennifer Dazey

Browse all Theses and Dissertations

Maternal separation has been shown to promote the onset of depression. This early life stressor produces a biphasic response marked by an active "protest" phase followed by a passive "despair" phase in humans as well as several other species. In infant guinea pigs, active phase behaviors include increased locomotion and species-typical distress vocalizations, whereas the passive phase is marked by depressive-like behaviors including a crouched stance, eye-closure and extensive piloerection. The mechanism underlying the transition from one phase to the next is still unknown. The purpose of this study was to determine if daily stimulation of the neural pathway initiating …

Glutamate Receptor-Mediated Taurine Release From The Hippocampus During Oxidative Stress, Brian Christopher Tucker

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Oxidative stress is an important result of cerebral ischemia and has been directly linked to hippocampal swelling and cytotoxic brain edema in vitro. Swollen brain cells activate volume regulatory mechanisms including a significant efflux of the endogenous sulfonic amino acid taurine via volume-regulated anion channels (VRACs). Studies in brain slice preparations also suggest that the excitatory amino acid glutamate plays an important role in both brain tissue swelling and in cell volume regulation. We examined relationships between oxidative stress, glutamate receptor activation, cell swelling, and volume regulation in acutely prepared slices of rat hippocampus. Our results indicate that the release …

Obesity: The Anthropometric And Demographic Characteristics Of Insured And Uninsured Individuals, Terra Fox Williams

Master of Public Health Program Student Publications

Objectives. This study evaluates the association between Body Mass Index (BMI) and health insurance status in attendees at a local health fair. BMI was also compared among ages, gender, and races.

Methods. Descriptive analysis conducted using data collected at the “Celebrating Life and Health” health fairs between the years 2008 and 2011. Data for this study were collected at the BMI booth staffed by Wright State Boonshoft School of Medicine students.

Results. The results of this particular study do not demonstrate a statistical difference between obesity and health insurance status. Consistent with other research articles this study does show that …

The Role Of Supermarkets In Community Nutrition, Staci Gruber

Master of Public Health Program Student Publications

Background: Chronic diseases related to nutrition are a serious threat to public health. Supermarkets offer an important and promising venue to improve diet quality and overall health. The purpose of this study is to evaluate the supermarkets’ community nutrition focus and interest in public health.

Methods: This study emphasis’s a triangulated qualitative study design. It employs various methods and taps various sources for data. Twenty face-to-face, semi-structured key informant interviews were conducted with five full service supermarket chains in Montgomery County, Ohio; Wal-Mart, Kroger, Meijer, Cub Foods, and Dorothy Lane Market. Qualitative sources of information collected include store observation and …

Evaluation Of Cancer From Exposure To Cyanotoxins In Drinking Water At Grand Lake Saint Marys, Timothy Edward Soward

Master of Public Health Program Student Publications

Background: The Celina Water Department treats and supplies surface water contaminated by cyanotoxins from Grand Lake Saint Marys (GLSM) to approximately 12,000 customers in Celina, Ohio. Cyanotoxins are a biochemically and bioactively diverse group of extremely potent natural toxins in water. A common cyanotoxin called microcystin-LR found in GLSM has been associated with acute liver damage and potentially liver and colorectal cancer.

Methods: In this observational study, the city of Celina (Mercer County) Ohio that had a contaminated surface water supply, the cancer incidence was compared with two control cities, St. Marys, and Wapakoneta (Auglaize County) in Ohio, both served …

Colostrum Avoidance, Prelacteal Feeding And Late Breast-Feeding Initiation In Rural Northern Ethiopia, Nikki Lynn Rogers, Jemilla Abdi, Dennis Moore, Sarah Nd'iangui, Linda J. Smith, Andrew J. Carlson, Dennis Carlson

Population and Public Health Sciences Faculty Publications

Objective

To identify specific cultural and behavioural factors that might be influenced to increase colostrum feeding in a rural village in Northern Ethiopia to improve infant health.

Design

Background interviews were conducted with six community health workers and two traditional birth attendants. A semi-structured tape-recorded interview was conducted with twenty mothers, most with children under the age of 5 years. Variables were: parental age and education; mother's ethnicity; number of live births and children's age; breast-feeding from birth through to weaning; availability and use of formula; and descriptions of colostrum v. other stages of breast milk. Participant interviews were …

Are Student Nurses Ready For Disasters? An Analysis Of Emergency Preparedness Content In Nursing School Textbooks Used In The Miami Valley, Kimberly Caudill

Master of Public Health Program Student Publications

Results of an analysis of nursing textbooks used in the Miami Valley, indicate that there is minimal emergency preparedness content included. The research was based on the textbooks used in the Introduction to Nursing, Psychiatric Nursing, and Community Health Nursing classes at four local nursing schools: Sinclair Community College, Kettering College of Medical Arts, Cedarville University, and Wright State University. The Community Health Nursing classes have the most prepared content, and include extra content in the form of tables and pictures .The analysis indicates that Wright State University does the best job at preparing student nurses to be ready to …

Assessment Of Refugees’ Health In Montgomery County: A Case Study Of Refugees From Rwanda And Burundi, Jean De Dieu Mukunzi

Master of Public Health Program Student Publications

The purpose of this research study was to identify health needs and health problems experienced by a refugee/asylee population in Montgomery County. Montgomery County hosts a large number of refugees, asylees and asylum seekers from countries such as Iraq, Ethiopia, Eritrea, Soudan, Rwanda, Burundi and Congo.

A public health challenge is limited demographic data about this population. The scarce data on their health needs slows down not only their successful resettlement but also limits community organizations, health and human services agencies to improve the delivery of health care services and health promotion programs to refugees and immigrants in Montgomery County. …

Management Of Professional Boundaries In Rural Primary Care, Kathleen D. Brooks, Rebekah Pratt, Diann S. Eley, Therese M. Zink

Family Medicine Faculty Publications

No abstract provided.

Suicide Prevention, Recovery And Clinical Supervision, John R. Cutcliffe

Nursing Faculty Publications

No abstract provided.

Flight Physician - August, 2011, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A sixteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Comparing Cognitive Functioning And Adverse Metabolic Effects Of Consumers Taking Type 1 Or Type 2 Antipsychotic Medications With Un-Medicated Consumers, Muhammad Puri

Master of Public Health Program Student Publications

Obesity and metabolic side effects such as diabetes mellitus are major concerns in public health. Mentally ill people are a high risk subgroup for obesity and metabolic syndrome because of behavior, non treatment, and medication side effects. In this research, I conducted a retrospective chart review to compare the weight and body mass index of consumers who were prescribed antipsychotic Type 1 or Type 2 medications. The sample was drawn from consumers attending the Consumer Advocacy Model (CAM) program which is an outpatient substance abuse and mental health treatment program in the Wright State University Boonshoft School of Medicine Department …

Caenorhabditis Briggsae Recombinant Inbred Line Genotypes Reveal Inter-Strain Incompatibility And The Evolution Of Recombination, Joseph A. Ross, Daniel C. Koboldt, Julia E. Staisch, Helen M. Chamberlin, Bhagwati P. Gupta, Raymond D. Miller, Scott Everet Baird, Eric S. Haag

Biological Sciences Faculty Publications

The nematode Caenorhabditis briggsae is an emerging model organism that allows evolutionary comparisons with C. elegans and exploration of its own unique biological attributes. To produce a high-resolution C. briggsae recombination map, recombinant inbred lines were generated from reciprocal crosses between two strains and genotyped at over 1,000 loci. A second set of recombinant inbred lines involving a third strain was also genotyped at lower resolution. The resulting recombination maps exhibit discrete domains of high and low recombination, as in C. elegans, indicating these are a general feature of Caenorhabditis species. The proportion of a chromosome's physical size occupied by …

Holland, Cindra Interview For The Miami Valley College Of Nursing And Health Oral History Project, Donna M. Curry, Natasha Clinton, Stacy Harris, Cindra Holland

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Donna Miles Curry, Stacy Harris, and Natasha Clinton interviewed Cindra Holland about the history of the Doctor of Nursing Practice program at Wright State University. In the interview Dr. Holland discusses her education as well as attending the DNP program.

Toxic Chemicals Transported By Rail And Public Health Safety Using Gis In Montgomery County, Ohio, Jason Lipiec

Master of Public Health Program Student Publications

Hazardous chemicals transported by rail pass directly through urban cities and pose a safety and health threat to the community. Some of these chemicals can be in large quantities, extremely toxic, devastating to the environment and have the potential to cause mass casualties and death. Thousands of people could be in harm’s way. While there is always the possibility for accidental chemical release, they also have the potential to be used in acts of sabotage and terrorism. Evaluation of the rail line in Montgomery County, Ohio using standards in the 2008 Emergency Response Guidebook using geographic information systems (GIS) at …

The Non-Infectious Disease Implications Of Bed Bug Infestations, Christopher T. Balster

Master of Public Health Program Student Publications

The purpose of this study was to determine the prevalence of bed bug infestations throughout Ohio, whether the non-infectious disease implications of infestations are public health concerns, and also determine the perceived ability of public health departments to respond to outbreaks within their jurisdiction. A descriptive study was performed using survey data obtained from 79 local public health departments throughout Ohio. Overall, 79.05% of individuals surveyed agreed that bed bug outbreaks are a public health concern. The mode of responses regarding whether or not the non-infectious disease concerns of infestations are a public health concern was 4 on a scale …

Abnormal Placental Findings Associated With Non-Reassuring Fetal Monitoring And Excellent Neonatal Outcomes, Gary Ventolini, Shanthi Ramesh, Sheela M. Barhan, Ran Neiger

Obstetrics and Gynecology Faculty Publications

Objective: Obstetricians, Neonatologists, and Pathologists have studied gross histological analysis of human placentas in search of specific alterations in placental functions that can be correlated with neonatal outcomes. Our study assessed the prevalence of abnormal placental findings associated with non-reassuring fetal monitoring in labor requiring emergent instrumental or cesarean delivery, followed by an excellent neonatal outcome. Study Design: One hundred consecutive emergency deliveries, instrumental or cesarean, performed due to non-reassuring fetal monitoring while in labor were retrospectively evaluated. All patients were low-risk for obstetric complications, and had a singleton, term pregnancy. They had a normal antenatal routine testing and a …

Loss Of Expression Of Neutrophil Proteinase-3: A Factor Contributing To Thrombotic Risk In Paroxysmal Nocturnal Hemoglobinuria, Anna M. Jankowska, Hadrian Szpurka, Mark Calabro, Sanjay Mohan, Andrew E. Schade, Michael Clemente, Roy L. Silverstein, Jaroslaw P. Maciejewski

Biological Sciences Faculty Publications

Background: A deficiency of specific glycosylphosphatidyl inositol-anchored proteins in paroxysmal nocturnal hemoglobinuria may be responsible for most of the clinical features of this disease, but some functional consequences may be indirect. For example, the absence of certain glycosylphosphatidyl inositol-anchored proteins in paroxysmal nocturnal hemoglobinuria cells may influence expression of other membrane proteins. Membrane-bound proteinase 3 co-localizes with glycosylphosphatidyl inositol-linked neutrophil antigen 2a, which is absent in patients with paroxysmal nocturnal hemoglobinuria. Design and Methods: We compared expression of proteinase 3 and neutrophil antigen 2a by flow cytometry and western blotting in normal and paroxysmal nocturnal hemoglobinuria cells and measured cytoplasmic …