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Pitfalls And Artifacts In Nuclear Imaging Studies, Leonard M. Freeman

MCV/Q, Medical College of Virginia Quarterly

In interpreting scintillation images, one often is confronted with a variety of deviations from the typically normal study that need not represent definite pathology. Apart from normal anatomic variants in the position, shape, or configuration of an organ, one must also be prepared to appreciate alterations due to the radiodiagnostic agent employed and aberrations caused by faulty or improperly used instruments. Additionally, physiologic and/or functional changes associated with specific organ studies have provided a major source of error in routine image interpretation. It is the purpose of this article to acquaint (or reacquaint, as the case may be) the reader …

Author Index, Volume Eleven, 1975.

MCV/Q, Medical College of Virginia Quarterly

Author index for MCV/Q, Medical College of Virginia Quarterly, 1975, Volume Eleven.

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 11 No. 4

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Scintiphotography In Evaluation Of Renal Transplants, Halcott T. Haden

MCV/Q, Medical College of Virginia Quarterly

Renal transplantation has progressed from the research stage to become a standard clinical procedure. Although still generally limited to large medical centers, renal transplants are regularly done in over 135 hospitals in the United States. In 1972, approximately 2,600 renal transplants were recorded in the United States by the Renal Transplant Registry. Approximately 65% of these were cadaver donors and 35% living donors.

Radioimmunologic Methods For Diagnosis Of Malignant Diseases, Paul B. Hoffer

MCV/Q, Medical College of Virginia Quarterly

The recent availability of the carcinoembryonic antigen (CEA) assay has stimulated great clinical interest in tumor antigens. Carcinoembryonic antigen is not the only specific or tumor-associated antigen currently identified. There are a number of other tumor antigens which have been isolated, some of which are related to CEA and some of which are totally different. There is, for example, a nonspecific cross-reacting antigen (NCA) which has been discovered in certain preparations which were considered originally to be CEA. Nonspecific cross-reacting antigen is a beta globulin (25% carbohydrate) which cross-reacts with antibodies to CEA and may be the nonspecific background element …

Modern Management Of Diabetic Pregnancies, Elsie R. Carrington

MCV/Q, Medical College of Virginia Quarterly

On a broad national basis, it should be quite possible to substantially reduce maternal morbidity and the disproportionately high numbers of perinatal losses associated with diabetic pregnancies. Nationwide, the overall perinatal mortality rate for this group is approximately 20%, which is at least double that incurred in centers where intensive care facilities and personnel are available, and consistent, well-coordinated care by the health team is provided. Although the prognosis for fetal survival is less favorable with advances in severity of the diabetic state, there is a significant risk even during the mildest stage of the disease. Careful prospective studies, notably …

The Birth Of A New Department At Mcv/Vcu-Human Genetics, Peter Mamunes

MCV/Q, Medical College of Virginia Quarterly

In recognition of the central role of genetics in the health professions, the MCV/VCU School of Basic Sciences and Graduate Studies substantially enlarged its commitment to this discipline by creating a new Department of Human Genetics as of September 1, 1975, under the chairmanship of Walter E. Nance, M.D, Ph.D., an internationally renowned medical geneticist. Dr. Nance comes to Richmond from Indianapolis where he was Professor of Medicine and Medical Genetics at the Indiana University School of Medicine. Here at MCV/VCU, Dr. Nance will also have joint appointments in both the Departments of Medicine and Pediatrics.

Contents

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1975, Volume Eleven, Number One.

Amenorrhea Due To Defects In Steroid Biosynthesis, H. Oliver Williamson, Rajesh S. Mathur

MCV/Q, Medical College of Virginia Quarterly

Amenorrhea as the first manifestation of a steroid biosynthetic defect is rather unusual. The common forms of congenital adrenal hyperplasia are classic examples of steroid biosynthetic defects. Yet in genotypic females, this disorder is usually evident from birth because of virilization. Effective treatment usually ensues and amenorrhea is only a problem when control is inadequate. However, there are individuals whose disorder will be manifest for the first time in the postnatal or adult period. In addition, multiple other steroid defects have now been clearly delineated. Many of these individuals will have amenorrhea, virilization, or sexual ambiguities as part of the …

Radical Hysterectomy For Carcinoma Of The Cervix, John J. Mikuta

MCV/Q, Medical College of Virginia Quarterly

Radical hysterectomy refers to the removal of the uterus and cervix and, in addition, to the removal of the upper one-half to one-third of the vagina, the parametria and the pelvic lymph nodes. This operation, which is commonly called the Wertheim operation, was actually first described by Clark in the United States and Ries in Germany. Wertheim's original operation for carcinoma of the cervix consisted only of a partial parametrial removal and removal of the upper one-third of the vagina. It did not include pelvic lymphadenectomy or the removal of the lateral portions of the parametria.

Some Practical Thoughts On Medical Malpractice, Robert L. Harris

MCV/Q, Medical College of Virginia Quarterly

Today more malpractice suits are being filed than ever before. Not only are more suits being filed but the amount of settlements and verdicts has significantly increased. Perhaps one of the primary reasons for this phenomenon is the consumerists movements. Obviously, the more consumer groups advocate consumer protection, and the more that juries render favorable verdicts, the better educated and aware of verdicts the consumer becomes. The result of this is that people become more litigation conscious. In Virginia, medical malpractice litigation appears to be just beginning to flourish in relation to other large urban areas in the North and …

Subject Index, Volume Eleven, 1975.

MCV/Q, Medical College of Virginia Quarterly

Subject Index for MCV/Q, Medical College of Virginia Quarterly, 1975, Volume Eleven.

Virginia Dental Journal (Vol. 52, No. 4, 1975)

Virginia Dental Journal

No abstract provided.

Radiopharmaceutical Production And Quality Control, Jerry I. Hirsch

MCV/Q, Medical College of Virginia Quarterly

With the development of shorter-lived, organ-specific radiopharmaceuticals, much of the manufacture and quality control of these products have shifted from commercial manufactures to individual nuclear medicine laboratories. Recognizing this fact, the Nuclear Regulatory Commission (NRC) is encouraging quality assurance by proposing that "an authorized physician may permit technicians and other paramedical personnel to perform the preparation and quality control testing of radiopharmaceuticals..." Cohen has categorized pharmaceutical controls into chemical, biological, and physical. Figure 1 is a diagram of these controls. In each control a degree of purity is implied and is often determined by comparison to standard.

The Diagnosis And Treatment Of Carcinoma Of The Thyroid, Richard H. Kirkland

MCV/Q, Medical College of Virginia Quarterly

The major point I would like to make is that we should try to prevent thyroid carcinoma by administration of thyroid hormones to all patients with potentially high TSH and damaged-thyroid disease, using suppressive doses of levothyroxine. In my opinion, all patients who have thyroid disease should be treated with thyroid hormone indefinitely, once hyperthyroidism has been eliminated.

Introduction, Klaus Ranniger

MCV/Q, Medical College of Virginia Quarterly

In this issue, the MCV Quarterly continues to publish selected papers presented at the recent Postgraduate Course in Nuclear Medicine sponsored by the Department of Radiology of the Medical College of Virginia. The papers reflect modern in vitro and in vivo radioactive isotope applications. Once again the authors deserve our thanks for their enlightening contributions.

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 11 No. 3

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Differntial Diagnosis Of Hypertension, Andrew W. Dickinson Jr.

MCV/Q, Medical College of Virginia Quarterly

The overwhelming majority of hypertensive patients have essential hypertension, which is a potent risk factor in producing vascular disease. Overall, it must be stated that the differential diagnosis of hypertension is a relatively minor factor in approaching the tremendous challenge of detecting and adequately treating the overwhelming majority of patients who are now undetected, untreated, or inadequately treated.

Virginia Dental Journal (Vol. 52, No. 2, 1975)

Virginia Dental Journal

No abstract provided.

Hydrodynamic Structure Of Bovine Serum Albumin Determined By Transient Electric Birefringence, A. K. Wright, M. R. Thompson

Physiology and Biophysics Publications and Presentations

Birefringence relaxation studies on bovine serum albumin (BSA) reveal transient decay described by a double exponential process. The values of the relaxation times lead to estimation of the size of the equivalent ellipsoid of revolution for BSA. Previous measurements of transient birefringence for BSA have shown a single relaxation process, since the apparatus used in obtaining those data was not fast enough to detect the faster relaxation process.

A Survey Of Parental Knowledge Of Asthma, Nancy Aldred O'Donnell

Theses and Dissertations

The purpose of this study was to investigate the level of parents' knowledge regarding asthma.

Twenty-five parents of children who have asthma were interviewed during their child's hospitalization for status asthmaticus. Adequate knowledge about environmental control and medication was noted in the majority of the subjects but over half were unable to explain the pathological changes which caused wheezeing. While most parents appear to have adequate knowledge of medications and environmental control on which to base their decisions about their child’s care there appears to be a need for more information regarding the pathophysiology.

A Comparison Of Acrosomal Proteinase Activity In The Male And Female Reproductive Tracts Of The Guinea Pig, Thomas Joseph Morris

Theses and Dissertations

The spermatozoon has been the subject of numerous investigations because of its remarkable specialization for locomotion and fertilization. Although the spermatozoon of the guinea pig is relatively large when compared with other mammalian spermatozoa, its small size has hidden many of the details of its structure from the light microscopist. It was not until the invention of the electron microscope that a thorough study of spermatozoon structure could be accomplished. The following anatomical description is based on the works of Fawcett and Hollenberg (1963), Fawcett (1965), and Fawcett (1970). The principle parts of the guinea pig spermatozoon are the head …

The Morphologic Changes In The Muscles Of Mastication Due To Direct Intramuscular Injection Of Lidocaine, Carbocaine, Procaine And Citanest, Kurt Elliot Friedman

Theses and Dissertations

One of the most commonly experienced symptoms in dentistry and one that is of major concern to the dentist is pain. Since pain is manifested when an environmental change occurs causing injury to responsive tissues, it is often spoken of as a protective mechanism.

Pain has been described by a variety of terms: sharp, burning, aching, cramping, dull and throbbing! (Monheim, 1969). Therefore, it is a difficult term to define. Monheim (1969) describes pain as an unpleasant sensation created by a noxious stimulus that is mediated along specific nerve pathways into the central nervous system, where it is interpreted as …

Virginia Dental Journal (Vol. 52, No. 3, 1975)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 52, No. 5, 1975)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 52, No. 6, 1975)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 52, No. 1, 1975)

Virginia Dental Journal

No abstract provided.

An Evaluation Of Centrifuged Vs Electronically Determined Hematocrits In Assessing The Degree Of Polycythemia In Cyanotic Congenital Heart Disease, Marsha Rene Jones

Theses and Dissertations

Secondary polycythemia is defined as an absolute erythrocytosis caused by an enhanced stimulation of red blood cell production. One of the most common methods of monitoring the degree of polycythemia is the measurement of the hematocrit. The hematocrit is the measurement of the volume of red blood cells.expressed as a percentage of the volume of whole blood in a sample. This measurement is usually done using one of two methods: (1) the Coulter Model S® or (2) the centrifuged micro-hematocrit method. However, we have noted a significant difference in the hematocrit values determined by these two methods when the hematocrits …

Metastatic Patterns And Functional Disability In Disseminated Breast Carcinoma, Stephen Adam Gudas

Theses and Dissertations

Thirty female outpatients with metastatic breast carcinoma were evaluated using two operational models constructed for the purpose of assessing and assigning a quantitative score for (A) extent of metastatic disease and (B) level of functional disability. These patients were drawn from the population of patients with disseminated breast carcinoma attending the medical oncology clinics at the Medical College of Virginia Tumor Clinics for a 49 day period in 1975. The data from this patient sample were used to test several hypotheses.

Each patient underwent an initial screening procedure designed to clearly identify those patients with disseminated disease. This was followed …

Contents

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1974, Volume Ten, Number One.