Medicine and Health Sciences Commons^™

Mental Health Research Productivity Of Nasp-Approved School Psychology Programs: 2010-2015, Mala Nash

UNLV Theses, Dissertations, Professional Papers, and Capstones

With the evident need for mental health support of children and adolescents, there are identified professionals prepared to provide services within the school setting. The school psychologist is considered a key resource for providing mental health services such as preventive and crisis response (Dwyer, 2004; Armistead, 2008). Based on our country’s mental health needs and the significant role that schools can make in meeting those needs, it is pertinent to take a closer look at the literature specifically related to mental health. This review focused specifically on the field of school psychology’s contribution to mental health literature and established a …

An Evaluation Of Alzheimer's Disease-Related Pathology In Two Different Models Of Diabetes In Immune-Challenged Mice, Andrew Scott Murtishaw

UNLV Theses, Dissertations, Professional Papers, and Capstones

Obesity, type 2 diabetes mellitus (T2DM), and metabolic syndrome are related disorders with wide-ranging and devastating effects that can be observed throughout the body. One important and understudied organ of damage is the brain. Clinical and epidemiological studies have found that T2DM, and more specifically hyperinsulinemia, significantly increases the risk of cognitive decline and increases the likelihood of Alzheimer’s disease (AD) and other forms of dementia in the elderly. Insulin has slightly different functions in the peripheral body than in the central nervous system and the dysregulation of these functions may contribute to the onset and progression of late-life neurodegenerative …

Handgrip Fatigue And Forearm Girth In Intermediate Sport Rock Climbers, Grace Antoinette Macdonald

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Rock climbing has been increasing in popularity both recreationally and competitively. Indoor sport rock climbing is a type of climbing where the climber ascends a wall using artificial rocks (hand and foot holds) and is attached to a safety rope. Despite this increase in popularity of the sport, the physiological responses to sport climbing as an exercise to specific muscle groups are not well defined in literature. Purpose: The purpose of this study was to quantify the change in handgrip strength over a 30-minute bout of continuous climbing, specifically in intermediate sport climbers. An additional aim of this study …

Development Of An Evidence-Based Nursing Leadership Fellowship Program Guide, Jennie Noren

UNLV Theses, Dissertations, Professional Papers, and Capstones

Faced with an increasing demand for nurse leaders with competencies in effective inter-professional communication, change management, conflict resolution, business and financial acumen, and the ability to lead both within and across systems, the current practice of promoting the highest skilled clinicians into leadership positions is not effective. Leadership skills which have been demonstrated in the literature to generate successful and impactful leaders must be provided through immersive educational experiences in an efficient and effective manner to produce leaders who can promote the transformation of healthcare at all levels with confidence. This DNP Project has created a guide for an evidence-based …

Electronic Health Record Instruction In First-Semester Nursing Students: A Comparative Study, Angela Ruckdeschel

UNLV Theses, Dissertations, Professional Papers, and Capstones

The use of health information technology has been shown to have positive effects on patient outcomes and provider efficiency. New nurses make more than half of the 7 million life-threatening medication errors that occur each year, and electronic health records (EHRs) have been shown to significantly reduce these errors. Nurses now are expected to enter practice with a solid foundation in health information technology and the use of the EHR. Unfortunately, the vast majority of nursing schools do not specifically train their students in effective EHR utilization. Academic EHRs (AEHRs) are software packages with learning features that can be incorporated …

Efficacy Of Combined 5-Fluorouracil And Photodynamic Therapy In Glioma Spheroids, Karanjit Singh

UNLV Theses, Dissertations, Professional Papers, and Capstones

Standard treatment regimens consisting of surgery, radiation and chemotherapy have proven ineffective for the treatment of high-grade gliomas such as glioblastoma multiforme (GBM). An effective cure requires elimination of nests of tumor cells that have migrated from the resection margin and infiltrated normal brain. A number of localized therapies, including light-based approaches such as photodynamic therapy (PDT) and photochemical internalization (PCI) are currently under investigation for the management of GBM patients.

Several studies have demonstrated a high degree of synergy between PDT and bleomycin, via the PCI mechanism, in a variety of in vitro and in vivo models, including glioma …

Designed Environment For Healthy Aging, Attila Lawrence

Architecture Faculty Research

A growing number of aging adults want to remain in multi generational communities rather than relocating to retirement communities, or having to resort to an institutional setting. To productively function in an environment where all generations interact and live well together, however, one’s ability to manage diminishing cognitive and physical conditions precipitated by the aging process is a major factor that bears on everyone’s quality of life. Because the designed environment frequently plays a significant role in the occurrence of neurodegenerative disorders that involve biological changes, it is self-evident that design strategies intended to support the management of these symptoms …

Bibliometric Analysis Of Gaps In Research On Asbestos-Related Diseases: Declining Emphasis On Public Health Over 26 Years, Ro-Ting Lin, Matthew John Soeberg, Lung-Chang Chien, Scott Fisher, Jukka Takala, Richard Lemen, Tim Driscoll, Ken Takahashi

School of Public Health Faculty Research

Objectives The global burden of asbestos-related diseases (ARDs) is significant, and most of the world’s population live in countries where asbestos use continues. We examined the gaps between ARD research and suggestions of WHO and the International Labour Organization on prevention. Methods From the Web of Science, we collected data on all articles published during 1991–2016 and identified a subset of ARD-related articles. We classified articles into three research areas—laboratory, clinical and public health—and examined their time trends. For all and the top 11 countries publishing ARD-related articles, we calculated the proportions of all ARD-related articles that were in each …

Wide Educational Disparities In Young Adult Cardiovascular Health, Elizabeth M. Lawrence, Robert A. Hummer, Benjamin W. Domingue, Kathleen Mullan Harris

Sociology Faculty Research

Widening educational differences in overall health and recent stagnation in cardiovascular disease mortality rates highlight the critical need to describe and understand educational disparities in cardiovascular health (CVH) among U.S. young adults. We use two data sets representative of the U.S. population to examine educational disparities in CVH among young adults (24–34) coming of age in the 21st century: the National Health and Nutrition Examination Survey (2005–2010; N= 689) and the National Longitudinal Study of Adolescent to Adult Health (2007–2008; N=11,200). We employ descriptive statistics and regression analysis. The results show that fewer than one in four young adults had …

Provider Perspectives On Demand Creation For Maternal Vaccines In Kenya, Irina Bergenfeld, Stacy W. Nganga, Courtni A. Andrews, Vincent L. Fenimore, Nancy A. Otieno, Sandra S. Chaves, Jennifer R. Verani, Marc-Alain Widdowson, Winnie N. Wairimu, Susan N. Wandera, Raphael O. Atito, Maxwell O. Adero, Paula M. Frew

Environmental & Global Health Faculty Research

Background. Expansion of maternal immunization, which offers some of the most effective protection against morbidity and mortality in pregnant women and neonates, requires broad acceptance by healthcare providers and their patients. We aimed to describe issues surrounding acceptance and demand creation for maternal vaccines in Kenya from a provider perspective. Methods. Nurses and clinical officers were recruited for semi-structured interviews covering resources for vaccine delivery, patient education, knowledge and attitudes surrounding maternal vaccines, and opportunities for demand creation for new vaccines. Interviews were conducted in English and Swahili, transcribed verbatim from audio recordings, and analyzed using codes developed from interview …

A Novel Deep Learning Framework For Internal Gross Target Volume Definition From 4d Computed Tomography Of Lung Cancer Patients, Xiadong Li, Ziheng Deng, Qinghua Deng, Lidan Zhang, Tianye Niu, Yu Kuang

Health Physics and Diagnostic Sciences Faculty Research

In this paper, we study the reliability of a novel deep learning framework for internal gross target volume (IGTV) delineation from four-dimensional computed tomography (4DCT), which is applied to patients with lung cancer treated by Stereotactic Body Radiation Therapy (SBRT). 77 patients who underwent SBRT followed by 4DCT scans were incorporated in a retrospective study. The IGTV_DL was delineated using a novel deep machine learning algorithm with a linear exhaustive optimal combination framework, for the purpose of comparison, three other IGTVs base on common methods was also delineated, we compared the relative volume difference (RVI), matching index (MI) and encompassment …

Emergent Chest Wall Reconstruction For An Incarcerated Pulmonary Hernia, Allison G. Mcnickle Md, Timonthy Dickhudt Md, Jorge A. Vega Md, Paul J. Chestovich, Douglas R. Fraser

School of Medicine Faculty Research

No abstract provided.

Barriers To Dietary Salt Reduction Among Hypertensive Patients, Saruna Ghimire, Naveen Shrestha, Karen E. Callahan

School of Public Health Faculty Research

Background: Despite knowing the ill consequences of high salt intake, many hypertensive patients in Nepal continue to consume high levels of salt in their diet. Hence, this study aims to reveal the barriers to dietary salt reduction among hypertensive patients in Nepal. Methods: A barrier analysis was conducted in the outpatient department of Sahid Gangalal National Heart Center, Nepal among 180 hypertensive patients under physician advice to reduce salt in their diet. A logistic regression modeling was used to calculate odds ratios (ORs) for the barriers...(See full text for complete abstract)

The Fight For Birth, Jessica E. Brown

Research Briefs

No abstract provided.

Nonlinear Associations Between Working Hours And Overwork-Related Cerebrovascular And Cardiovascular Diseases (Ccvd), Ro-Ting Lin, Lung-Chang Chien, Ichiro Kawachi

School of Public Health Faculty Research

Long working hours are recognized as a risk factor for cerebrovascular and cardiovascular diseases (CCVD). We investigated the relationship between working hours and different CCVD severity outcomes—death, disability, and illness—across industries in Taiwan from 2006 to 2016. We applied a generalized additive mixed model to estimate the association between working hours and the rate of each severity outcome, adjusted for salary, unemployment rate, time, and a random intercept. Industry-average working hours were significantly associated with each outcome level of overwork-related CCVD, especially when monthly working hours increased from 169 (relative risk [RR] = 1.46, 95% confidence interval [CI] 1.002–2.12) to …

Selective Use Of Pericardial Window And Drainage As Sole Treatment For Hemopericardium From Penetrating Chest Trauma, Paul J. Chestovich Md, Christopher F. Mcnicoll, Douglas R. Fraser, Purvi P. Patel, Deborah A. Kuhls, Esmeralda Clark, John J. Fildes

School of Medicine Faculty Research

Background

Penetrating cardiac injuries (PCIs) are highly lethal, and a sternotomy is considered mandatory for suspected PCI. Recent literature suggests pericardial window (PCW) may be sufficient for superficial cardiac injuries to drain hemopericardium and assess for continued bleeding and instability. This study objective is to review patients with PCI managed with sternotomy and PCW and compare outcomes.

Methods

All patients with penetrating chest trauma from 2000 to 2016 requiring PCW or sternotomy were reviewed. Data were collected for patients who had PCW for hemopericardium managed with only pericardial drain, or underwent sternotomy for cardiac injuries grade 1–3 according to the …

Variation In Airborne Pollen Concentrations Among Five Monitoring Locations In A Desert Urban Environment, Tanviben Y. Patel, Mark P. Buttner, David Rivas, Chad L. Cross, Dennis A. Bazylinski, Joram S. Seggev

Environmental & Global Health Faculty Research

The urbanization of the Las Vegas Valley has transformed this part of the Mohave Desert into a green oasis by introducing many non-native plant species, some of which are allergenic. Typically, one monitoring station is established per city to obtain pollen counts for an entire metropolitan area. However, variations in pollen concentrations could occur among different microenvironments. The objective of this study is to measure and compare pollen concentrations in five locations in Las Vegas to determine if there are significant differences between microenvironments within the city. Air samples were collected from five sites across the Las Vegas Valley over …

Pediatric To Adult Healthcare Transitioning For Adolescents Living With Hiv In Nigeria: A National Survey, Okikiolu A. Badejo, William A. Menson, Nadia A. Sam-Agudu, Jennifer Pharr, Salome Erekaha, Tamara Bruno, Gift Nwanne, Olabanjo Ogunsola, Jude Ilozumba, Olusegun Busari, Echezona E. Ezeanolue

School of Public Health Faculty Research

Introduction The period of transition from pediatric to adult care has been associated with poor health outcomes among 10–19 year old adolescents living with HIV (ALHIV). This has prompted a focus on the quality of transition services, especially in high ALHIV-burden countries. Due to lack of guidelines, there are no healthcare transition standards for Nigeria’s estimated 240,000 ALHIV. We conducted a nationwide survey to characterize routine transition procedures for Nigerian ALHIV. Materials and methods This cross-sectional survey was conducted at public healthcare facilities supported by five local HIV service implementing partners. Comprehensive HIV treatment facilities with ≥1 year of HIV …

Sex Moderates The Impact Of Diagnosis And Amyloid Pet Positivity On Hippocampal Subfield Volume, Jessica Z. K. Caldwell, Jody-Lynn Berg, Guogen Shan, Jeffrey L. Cummings, Sarah J. Banks

School of Public Health Faculty Research

We examined moderation effects of sex and diagnosis on the effect of positive florbetapir positron emission tomography (PET) amyloid-β (Aβ) scan (A+) on hippocampus subfield volumes in 526 normal control (NC) and early mild cognitive impairment (eMCI) participants from the Alzheimer’s Disease Neuroimaging Initiative (ADNI2; ADNI-GO). Regression moderation models showed that women— but not men— with NC designation did not show reduced subiculum volumes despite A+. At the eMCI stage, A+ was detrimental across sexes. Findings were significant while accounting for the effects of age, cognition at screening, education, and APOE4 carrier status. These findings suggest that women with A+ …

Life Satisfaction Among Elderly Patients In Nepal: Associations With Nutritional And Mental Well-Being. Health And Quality Of Life Outcomes, Saruna Ghimire, Binaya Kurmar Baral, Isha Karmacharya, Karen E. Callahan, Shiva Raj Mishra

School of Public Health Faculty Research

Nepal’s demography is aging rapidly, yet few studies to date have examined how this has affected the health and well-being of the elderly, defined as those above 60 years in Nepal’s Senior Citizen Act (2006). Our study, abbreviated NepEldQOLII, aims to assess perceived life satisfaction, and evaluate its relationship with nutritional health and mental well-being among the burgeoning Nepalese elderly population...(See full text for complete abstract)

Ptsd Among Working Women In A Developing Country, Lung-Chang Chien, Taylor J. Fitch, Xiao Yu, Mohammad Monjural Karim, Hasanat Alamgir

Research Briefs

No abstract provided.

Variations In Institutional Review Board Processes And Consent Requirements For Trauma Research: An East Multicenter Survey, Jeffry Nahmias, Areg Grigorian, Scott Brakenridge, Randeep S. Jawa, Daniel N. Holena, John Varujan Agapian, Brandon Bruns, Paul J. Chestovich, Bruce Chung, Jonathan Nguyen, Carl I. Schulman, Kristan Staudenmayer, Rachel Dixon, Jason W. Smith, Andrew C. Bernard, Jose L. Pascual

School of Medicine Faculty Research

Oversight of human subject research has evolved considerably since its inception. However, previous studies identified a lack of consistency of institutional review board (IRB) determination for the type of review required and whether informed consent is necessary, especially for prospective observational studies, which pose minimal risk of harm. We hypothesized that there is significant inter-institution variation in IRB requirements for the type of review and necessity of informed consent, especially for prospective observational trials without blood/tissue utilization. We also sought to describe investigators’ and IRB members’ attitudes toward the type of review and need for consent. Eastern Association for the …

Provider Insight On Surmounting Specialty Practice Challenges To Improve Tdap Immunization Rates Among Pregnant Women, Arpita Mehrotra, Allison Kennedy Fisher, Jennifer Mullen, Leslie Rodriguez, Angela J. Jiles, Alison P. Albert, Laura A. Randall, Paula M. Frew

Environmental & Global Health Faculty Research

Background Pertussis, or “whooping cough,” is an acute, contagious pulmonary disease that, despite being vaccine-preventable, has become an increasingly widespread problem in the United States. As a result, the Advisory Committee on Immunization Practices and American College of Obstetricians and Gynecologists updated recommendations stating clinicians should give a Tdap dose during every pregnancy, preferably at 27–36 weeks. Despite this recommendation, reported Tdap vaccine receipt rates during pregnancy vary from 16–61%, and previous studies have shown that clinician recommendation and vaccine administration are strongly associated with vaccine uptake among pregnant women. Methods Our aim was to inform new strategies to increase …

Convergent Roles Of De Novo Mutations And Common Variants In Schizophrenia In Tissue-Specific And Spatiotemporal Co-Expression Network, Peilin Jia, Xiangning Chen, Ayman H. Fanous, Zhongming Zhao

Psychology Faculty Research

Genetic components susceptible to complex disease such as schizophrenia include a wide spectrum of variants, including common variants (CVs) and de novo mutations (DNMs). Although CVs and DNMs differ by origin, it remains elusive whether and how they interact at the gene, pathway, and network levels that leads to the disease. In this work, we characterized the genes harboring schizophrenia-associated CVs (CVgenes) and the genes harboring DNMs (DNMgenes) using measures from network, tissue-specific expression profile, and spatiotemporal brain expression profile. We developed an algorithm to link the DNMgenes and CVgenes in spatiotemporal brain co-expression networks. DNMgenes tended to have central …

Birth History As A Predictor Of Adverse Birth Outcomes: Evidence From State Vital Statistics Data, Dejun Su, Kaeli Samson, Ashvita Garg, Corrine Hanson, Ann L. Anderson Berry, Ge Lin Kan, Ming Qu

School of Public Health Faculty Research

One of the most important predictors of preterm births (PTBs) or low-birth-weight births (LBWBs) is whether a mother has had a history of these birth outcomes. This study examined how different characterizations of birth history (e.g., any previous incidence of PTBs or LBWBs, immediate previous birth that was preterm or of low birth weight, and number of previous PTBs or LBWBs) were associated with PTBs or LBWBs. Based on birth records (n = 98,776) reported to the vital statistics electronic registration system in Nebraska from 2005 to 2014, mothers with a history of PTBs or LBWBs were more likely to …

Effect Of Exercise And Hypoxia On Plasma Telomerase, Charli D. Aguilar

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Telomerase reverse transcriptase (TERT) is the enzyme that adds telomeric sequences to the end of linear chromosomes. Exercise has shown to upregulate acutely leukocyte TERT after just 30 minutes of running on a treadmill at 80% of VO2max (Denham et al., 2016). Hypoxia inducible factor 1 (HIF-1) is also a mediator of TERT in in vitro (Nishi et al., 2004). Moderate acute exposure to hypoxia was associated with substantial increases in plasma TERT in a recent study on rats (Wang et al., 2014). The specific aim of the current study was to identify if acute hypoxia upregulates plasma TERT …

Implementing Evidenced-Based Tools And Obesity Bias Training When Counseling Overweight And Obese Truck Drivers, Sheryl M. Giordano

UNLV Theses, Dissertations, Professional Papers, and Capstones

Many Americans are either overweight or obese, but commercial truck drivers are at an even higher risk by nature of their occupation. The 2010 Survey of U.S. Long-Haul Truck Drivers found that 22.8% were overweight, 68.9% were obese, and 17.4% were considered morbidly obese. The concern is that obesity is a gateway to multiple medical disorders, to include obstructive sleep apnea, cancer, diabetes, and cardiac disease. Despite growing concerns of obesity, healthcare providers face problems when counseling and discussing the issue with patients. The failure of healthcare providers to discuss obesity or the impending issue with patients (i.e., truck drivers) …

Screening For The Novel Cariogenic Pathogen Scardovia Wiggsiae Among Orthodontic Patients, Adam Whiteley

UNLV Theses, Dissertations, Professional Papers, and Capstones

Screening for the Novel Cariogenic Pathogen Scardovia wiggsiae among Orthodontic Patients

by

Adam Whiteley

Dr. Karl Kingsley, Examination Committee Chair Professor of Biomedical Sciences University of Nevada, Las Vegas School of Dental Medicine

The recent discovery of a novel cariogenic pathogen Scardovia wiggsiae has led many scientists and oral health researchers to re-evaluate and re-examine existing saliva repositories to determine the prevalence among patient populations. Recent efforts at this institution have used existing saliva samples to determine the prevalence among both adults and pediatric patients. These studies have revealed this organism may be found in approximately one-quarter of all samples …

Design & Delivery Of Automated Winston-Lutz Test For Isocentric & Off-Axis Delivery Stability Utilizing Truebeam Developer Mode & Electronic Portal Imaging Device, Mahmoud Mohammad Yaqoub

UNLV Theses, Dissertations, Professional Papers, and Capstones

The uncertainties in treatment delivery cannot be ignored in radiation therapy. Thus, the quality assurance QA tests are very important task of the medical physicist in clinical practice. Assuring the coincidence between the mechanical isocenter of the Linear Accelerator (LINAC) and its radiation beams isocenter is one of the most important qualities need to be tested, and the Winston Lust (WL) test is the

most popular technique to perform this task, especially for the treatment modalities which need high precision in beam delivery such as the stereotactic radiosurgery/stereotactic body radiotherapy (SRS/SBRT). The linear accelerator-based SRS/SBRT is a well-established method in …

Implementing Dietary And Physical Activity Guidelines In A College Health Center, Terry Lynn Bartmus

UNLV Theses, Dissertations, Professional Papers, and Capstones

Obesity has been classified as a major national health care problem that results in a significant increase in morbidity, mortality, and health care related costs. Seventy percent of all adults age 18 and older have a body mass index (BMI) of 25 or greater, indicating they are overweight or obese. Thirty-six percent of college students are overweight or obese. Research has shown that lack of time has further decreased weight-related counseling by primary-care providers. Printed materials have been shown to be effective in cueing individuals to engage in healthy behaviors such as following physical activity and recommended nutritional guidelines. Currently, …