Medicine and Health Sciences Commons^™

Telemedicine And Advanced Technology Research Center: Quarterly Report, July 18, 2009 To October 17, 2009, Bea Babbitt

Telemedicine & Advanced Technology Research Center

Development of a P.O.I. and a Blended Learning Ecology for use in Combat Lifesaver Skills Training for the Army.

Early Childhood Summit On Comprehensive Services For Homeless Children And Their Families, Nevada Institute For Children’S Research And Policy, Nevada Head Start State Collaboration Office, Head Start State Training And Technical Assistance Office For Nevada, Nevada Public Health Foundation

Nevada Institute for Children's Research and Policy Reports

On October 23, 2009 the Nevada Head Start State Collaboration Office in partnership with the Nevada Institute for Children’s Research and Policy, Head Start State Training and Technical Assistance Office for Nevada and the Nevada Public Health Foundation sponsored the Early Childhood Summit on Comprehensive Services for Homeless Children and Their Families. The Summit brought together 142 professionals working with homeless children and families in Nevada from a variety of different organizations and backgrounds. The goal of the summit was to discuss the problem of families experiencing homelessness and offer solutions to professionals in how to better serve these populations.

Unlv Magazine, Matthew K. Jacobsen, Holly Ivy De Vore, Lisa Arth, Cate Weeks, Greg Lacour, Tony Allen, Afsha Bawany, Barbara Cloud, Gian Galassi, Phil Hagen, Karyn S. Hollingsworth, Michelle Mouton, Erin O'Donnell

UNLV Magazine

No abstract provided.

Quality Of Life Estimation With Structural Equation Modeling In School Aged Children With Asthma, Sheniz Moonie, Xuan Huang, David A. Sterling

Environmental & Occupational Health Faculty Publications

Significant increases in childhood asthma prevalence and mortality has prompted federal and regulatory agencies to work towards a national framework to address childhood asthma. Quality of life is an important component of chronic disease, and the evaluation of healthcare outcomes. There is little discussion in the literature regarding the implications of QoL as a theoretical construct. This study determined the effect of asthma on the QoL of our study population and caregiver’s missed workdays on the child’s QoL scores. A negative relationship was found between the child’s QoL and the caregiver’s missed workdays due to their child’s asthma. The use …

Effect Of Eicosapentaenoic And Docosahexaenoic Acid On Resting And Exercise Induced Inflammatory And Oxidative Stress Biomarkers: A Randomized, Placebo Controlled, Cross­Over Study, Richard Bloomer, Douglas Larson, Kelsey Fisher-Wellman, Andrew Galpin, Brian Schilling

Kinesiology and Nutrition Sciences Faculty Publications

No abstract provided.

The Regulation Of The Ospz And Orf-2 Promoters In The Shigella Flexneri By The Virulence Factor Virb, David Basta, Helen J. Wing

Undergraduate Research Opportunities Program (UROP)

Shigella flexneri is a pathogenic bacterium that is the causative agent of shigellosis, an illness characterized by severe dysentery. Shigella carries many of its virulence genes on a large virulence plasmid and consequently this plasmid is the focus of research in the Wing lab. My research focuses on the transcriptional regulation of a newly identified gene called ospZ. This gene’s protein product is secreted outside the bacterial cell and assists in polymorphonuclear leukocyte migration, a function that is believed to enhance the virulence of Shigella. Many genes encoded by the Shigella virulence plasmid are regulated by the transcription factor VirB, …

Pdest Fg12-Cmv Dsred Vector, Jarod Wolffis, Sheri L. Holmen

Undergraduate Research Opportunities Program (UROP)

Melanoma is the most rapidly increasing malignancy among young people in the United States. If detected early, the disease is easily treated; however, once the disease has metastasized it is largely refractory to conventional therapies and is associated with a high mortality rate. The development of human cancer from a pre-malignant primary tumor to a metastatic lesion that develops at secondary sites is thought to be a multi-step process, requiring many genetic and epigenetic events that provide a growth advantage to cells. It is still unclear which of the many genetic changes in human cancers are required for metastasis. Therefore, …

Mutations To Antibiotic Resistance During Stringent Response In B. Subtilis, Chad Hansen, Ronald E. Yasbin, Eduardo A. Robleto

Undergraduate Research Opportunities Program (UROP)

The relA gene in Bacillus subtilis controls a variety of factors during the stringent response which is a response to starvation of amino acids. The stringent response inhibits DNA synthesis and transcription of genes of tRNA, rRNA, and ribosomal proteins and promotes synthesis of the required amino acids. The objective of my project is to determine if a strain of B. subtilis that has a knockout mutation for the relA gene will accumulate a higher number of mutations that confer resistance to antibiotics that inhibit translation. It is proposed that because the relA gene inhibits transcription of ribosomal proteins, a …

Expression Of An Alternate Splice Form Of Bmi-1 In Multiple Myeloma, Adam Austin, Kristine Veys, Debbie Wong, James Tung

Undergraduate Research Opportunities Program (UROP)

The concept of “tumor stem cells” has garnered much attention in the last few years. Tumor stem cells are believed to exist among a heterogeneous group of cells that constitute a tumor. These tumor stem cells often express genes that are important for stem cell function, cell division, and maintenance of pluripotent state in stem cells. Stem cell or stem cell maintenance genes such as SALL 4 and Bmi-1 are often seen in these cancer cells and contribute to self-renewing divisions and cancer cell survival. In particular, high expression of Bmi-1 (B lymphoma mouse Moloney leukemia virus insertion region), a …

Survival Of Shigella Flexneri In Swimming Pool Water, Monique Gomez, Helen J. Wing

Undergraduate Research Opportunities Program (UROP)

Shigellosis is a disease caused by the pathogenic bacterium Shigella flexneri. The bacterium causes bloody diarrheadiarrhea, fever and abdominal pain. Infections can be and may cause fatal. . The disease may also cause bloody diarrhea and intense intestinal crampings. In the United States, there have been many outbreaks of shigellosis have been traced back to associated with inadequately disinfectedchlorinated public swimming pools and wading pools. These outbreaks of sShigellosis are most commonly seen among small children who play in these pools. . My goal is to determine how well Shigella survives in freshly chlorinated pool water and in pool water …

Undergraduate Research Opportunities Program, University Of Nevada Las Vegas, College Of Sciences

Undergraduate Research Opportunities Program (UROP)

No abstract provided.

Effect Of The Dietary Supplement Meltdown On Catecholamine Secretion, Markers Of Lipolysis, And Metabolic Rate In Men And Women: A Randomized, Placebo Controlled, Cross­Over Study, Richard Bloomer, Robert Canale, Megan Blankenship, Kelley Hammond, Kelsey Fisher-Wellman, Brian Schilling

Kinesiology and Nutrition Sciences Faculty Publications

No abstract provided.

Stigma Cities: Dystopian Urban Identities In The United States West And South In The Twentieth Century, Jonathan Lavon Foster

UNLV Theses, Dissertations, Professional Papers, and Capstones

This dissertation examines how historical events and representation of those events relative to the wider historical context have allowed the media, opinion setters, and the ordinary public to use the names of San Francisco, California, Birmingham, Alabama and Las Vegas, Nevada as denigrating adjectives and the effect of this usage on those cities. Exploration of Birmingham’s image as a racist city, San Francisco’s as a gay Mecca, and Las Vegas, Nevada’s as an adult playground or sinful city serves this purpose. These case studies support a central argument that the nature of place-based stigmatization’s influence depends upon ever-shifting cultural values …

Dmitri Shalin Interview With Jordan Scher About Erving Goffman Entitled "Erving Disavowed Psychiatric Functioning At St. Elizabeth’S, And I Explored Role-Playing And The Presentation Of Self In Schizophrenia", Jordan Scher

Bios Sociologicus: The Erving Goffman Archives

This interview with Jordan Scher, M.D., Ph.D., Honorary Member of Vienna Psychiatric Society, was recorded over the phone on March 17, 2009. Dmitri Shalin transcribed the interview, after which Dr. Scher edited the transcript, added a historical note on N.I.M.H., and approved posting the present text in the Erving Goffman Archives. Breaks in the conversation flow are indicated by ellipses. Supplementary information and additional materials inserted during the editing process appear in square brackets. Undecipherable words and unclear passages are identified in the text as “[?]”.

Inside Unlv, Diane Russell, Shane Bevell, Mamie Peers

Inside UNLV

No abstract provided.

An Evaluation Of Methicillin Resistant Staphylococcus Aureus Survival On Five Environmental Surfaces Under Two Different Humidities, With And Without The Addition Of Bovine Serum Albumin, Courtney Ann Coughenour

UNLV Theses, Dissertations, Professional Papers, and Capstones

The spread of antibiotic resistant bacteria is a major public health concern, as they result in greater healthcare costs and increased morbidity and mortality rates. Methicillin resistant Staphylococcus aureus (MRSA) is one organism of particular concern, with the number of infections increasing in epidemic proportion. Bacterial surface contamination with MRSA is significant, as it may serve as a reservoir for transmission and have negative health implications. The purpose of this study was to evaluate survival of MRSA on five environmental surface materials; glass, wood, vinyl, plastic, and cloth. The effect of relative humidity (RH) and bovine serum albumin (BSA) were …

Identifying Biomarkers For Resistance To Novel Cisplatin Analogues In Human Lung, Breast And Prostate Cancers, Becky Michelle Hess

UNLV Theses, Dissertations, Professional Papers, and Capstones

Cisplatin is a common therapeutic agent used in cancer treatment. Unfortunately, resistance to cisplatin in addition to severe side effects limits its use in cancer treatment. Two novel cisplatin analogues, 4DB and 4TB were shown to have varying cytotoxicity in lung, breast and prostate cancer cells. The hypothesis for this study states that the differences in 4DB and 4TB cytotoxicity among different tissue types is due to the type and efficiency of DNA repair mechanisms involved in response to these drugs.

To test the hypothesis, proteins involved in the rate limiting step of nucleotide excision repair (NER) and mismatch repair …

Mercury Concentrations In Muscle Tissue From Sportfish In Lake Mead, Nevada, Joanna L. Kramer

UNLV Theses, Dissertations, Professional Papers, and Capstones

Lake Mead is the largest reservoir by volume in the United States and provides fishing opportunities for numerous anglers. Considerable attention has been given to the bioaccumulation of methylmercury in fish tissues, however, no formal study utilizing approved USEPA methodology has been conducted to quantify the amount of mercury present in fish tissue from Lake Mead. The purpose of this study is to determine the concentrations of mercury present in the most commonly consumed fish from Lake Mead and to identify if any of the 4 major basins contain fish with elevated concentrations of mercury. Largemouth bass (n=49), striped bass …

Advance Practice Nurses Readiness To Change Assessment Methods In Parents Of Obese Children, Carolyn Leach

UNLV Theses, Dissertations, Professional Papers, and Capstones

The worldwide epidemic of child and adolescent overweight and obesity continues to increase at disturbing rates. Unhealthy dietary practice is one of multiple causative behaviors leading to child and adolescent overweight and obesity. This behavior can contribute to short and long-term health consequences. Parents are modulators in the development of children's dietary behavior practices. It is recommended clinical practice that pediatric nurse practitioners (PNPs) assess readiness to change behavior in parents of overweight or obese children. The components of the Prochaska and DiClemente's Transtheoretical Model (TTM) in correlation with the counseling style of Rollnick, Miller and Butler's methods of Motivational …

An Evaluation Of Plastic Toys For Lead Contamination In Day Care Centers In The Las Vegas Valley, Joseph Alan Greenway

UNLV Theses, Dissertations, Professional Papers, and Capstones

The harmful effect of childhood exposure to environmental lead continues to be a major health concern. This study examined lead contamination within the plastic of children's toys. It was also hypothesized that the use of lead as a stabilizer would result in higher incidents of elevated lead (> 600 ppm) in polyvinyl chloride plastics (PVC) than non-PVC plastics. It was also hypothesized that, due to the use lead chromate, yellow toys would have higher incidents of elevated lead (> 600 ppm) than toys of other colors. Toy samples were limited to those found in day care centers in Las Vegas, …

Evaluation Of X-Ray Fluorescence (Xrf) Lead Detection Method For Candy, Ashley Marie Phipps

UNLV Theses, Dissertations, Professional Papers, and Capstones

The harmful effects of childhood exposure to environmental lead continue to be a major health concern. Due to the significance of this hazard, a Healthy People 2010 objective was set to reduce all young children's blood lead levels to less than 10 micrograms per deciliter. Identification and removal of lead-contaminated candies is an integral part of the primary prevention of lead poisoning in children.

This research examined the efficacy of a protocol to use a portable XRF to screen candies for lead contamination. Method Detection Limits (MDLs) of 5.45 ppm and 7.05 ppm were determined in the Bulk Sample and …

Molecular Epidemiology Of Methicillin-Resistant Staphylococcus Aureus (Mrsa), Ilene Bautista

UNLV Theses, Dissertations, Professional Papers, and Capstones

Staphylococcus aureus is a frequent cause of a myriad of infections in hospitals, healthcare facilities and community settings. It is often related to skin and soft tissue infection, but it can also cause other diseases varying from food poisoning to endocarditis and toxic shock syndrome. According to a study by Kuehnert et al. (2006) there has been a strong association between Staphylococcus aureus (S. aureus) carriage and risk factors for subsequent infections. Subsequent infection from S. aureus , including methicillin-resistant S. aureus (MRSA) infection, can be projected by looking at the presence of S. aureus nasal colonization. The purpose of …

The Effect Of Concurrent Cell Phone Use And Walking On Gait Characteristics, Jennifer Marie Aldridge

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study examined the effects that cell phone use has on gait and situation awareness. Subjects (n=18; 24.67±3.60 yrs) completed three five-minute treadmill walking conditions (self-selected speed): (1) CONTROL (walking only), (2) TALK (walking and talking), and (3) TEXT (walking and texting). The number of detected lights presented in the visual field was recorded, as were kinematic data of the feet. Using a one-way repeated measure ANOVA it was determined light detection (F _(2,17) =39.777, p<0.001) and TC_min (F_(2,17) =8.574, p=0.001) were different between conditions. Specifically, light detection decreased during TEXT (2.6±2.2 lights) versus TALK (5.8±0.05 lights, p<0.001) or CONTROL (5.9±0.05 lights, p<0.001); TC_min decreased …

Photochemical Delivery Of Bleomycin In Malignant Glioma Cells, Joseph William Blickenstaff Iii

UNLV Theses, Dissertations, Professional Papers, and Capstones

Despite continued efforts, glioblastoma multiforme (GBM) remains an incurable form of primary brain cancer. Surgical resection followed by radiation treatment and chemotherapy have been the most effective modalities in prolonging median survival time to 14 months. This research aims to study the response of two different cell culture models to a novel drug delivery method termed photochemical internalization (PCI). PCI is a technique to improve the utilization of macromolecules (e.g. the chemotherapeutic drug bleomycin) in site-specific cancer therapy. This concept is based on the use of specially designed photosensitizers (e.g. aluminum phthalocyanine disulfonate; AlPcS _2a ) which preferentially localize in …

Women's Health And Fitness Magazines: An Accurate Portrayal?, Jennifer M. Shymansky

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study is a content analysis examining the representation of health information, particularly the leading causes of death, in cover story headlines of one year of the top women's health and fitness magazines: Prevention , Shape , Fitness , Self , Health and Women's Health. The study is grounded in social responsibility theory, a normative media theory. The findings show that women's health and fitness magazines' cover story headlines predominately discuss diet and exercise for weight loss, rather than the leading causes of death facing women. This under representation of actual societal health concerns can limit the vast readerships' health …

Asthma Severity In School-Children And The Quality Of Life Of Their Parents, Noelle S. Cerdan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background . The everyday management of a child with asthma can affect the parent's quality of life. Past studies which examined the effects of asthma characteristics of the child on parental quality of life have not reached a consensus over findings. Few studies examine parent characteristics such as mental health and sociodemographics on the quality of life of parents of asthmatic children.

Purpose . To examine the effect of asthma severity of school-children and sociodemographic characteristics onthe caregiver's quality of life. It also investigates whether agreement exists between the caregiver's perception of asthma severity and physician-diagnosed asthma severity.

Methodology . …

Using Thermoluminescent Dosimeters To Measure The Dose From High And Low Energy X-Ray Sources, Wesley Leon Boyd

UNLV Theses, Dissertations, Professional Papers, and Capstones

This work focused on using thermoluminescent dosimeters (TLDs) to measure the doses from two x-ray sources, a CT scanner and a linear accelerator (linac). In addition ion chambers were used to determine the isodose contours from the operation of the linac. 1mm x 1mm x 1mm TLD-100 microcubes were placed in a Lawrence Livermore National Laboratory (LLNL) torso phantom and irradiated using a Toshiba Aquilion One 320-Slice CT Scanner. Different thicknesses of shielding composed of antimony and bismuth powder suspended in an ethylene copolymer were used to shield the phantom and the dose reduction was measured. The dose reduction ranged …

Investigation Of Magnetic Resonance Imaging And Spectroscopy For The Detection Of Breast Cancer, Robert Thomas Etnire

UNLV Theses, Dissertations, Professional Papers, and Capstones

Magnetic resonance imaging (MRI) of the breast offers an alternative to screening mammography which may benefit those women at high risk for breast cancer, women under the age of 40, and those with dense breast tissue. One concern with MRI is the number of high false positives. Coupling MRI with magnetic resonance spectroscopy(MRS) may lower the number of false positives, and thus improve the diagnostic capabilities of MRI for the clinician. MRS for breast imaging focuses on the total choline containing compounds in the spectra in the suspected breast lesion to analyze areas of concern. The results of the study …

Predictors Of Hpv Knowledge And Awareness In Rural America, Melanee Dulfon

UNLV Theses, Dissertations, Professional Papers, and Capstones

Prior research has shown that overall awareness of HPV is low among women in America. Yet limited research exists as to the awareness of HPV among rural U.S. women. The goal of this study was to determine the factors that predict women's knowledge and awareness of HPV in rural America. Secondary data was utilized from the National Cancer Institute Health Information National Trends Survey (HINTS) of 2005. The sample consisted of 788 adult women over the age of 18 from rural areas of the U.S. Results indicated younger age, increased education, receipt of a Pap exam in over three years, …

What Makes Women Tired? A Community Sample, Donna E. Stewart, Susan Abbey, Marta Meana, Katherine M. Boydell

Psychology Faculty Research

We aimed to determine the major health concerns or problems of women and their personal attributions for the causes of their primary health concerns. We used a survey of women from the Toronto area attending a women's health symposium. Completed questionnaires were returned by 153 (85%) of 180 women attendees. Persistent fatigue was the primary and most commonly cited health concern. Fatigue was ranked first by 42 (27.5%) women and among the top 10 concerns by 123 (80.4%) women. Women attributed their fatigue to a combination of home and outside work (63.4%), poor sleep (38.2%), lack of time for self …