Medicine and Health Sciences Commons^™

Cue-Elicited Negative Affect In Impulsive Smokers, Neal Doran, Jessica Werth Cook, Dennis E. Mcchargue, Mark G. Myers, Bonnie Spring

Department of Psychology: Faculty Publications

Impulsivity is associated with cigarette smoking, but the nature of this relationship and the mechanisms that maintain it are relatively unknown. The relationship has often been thought to reflect appetitive processes, but research suggests that an affective pathway exists as well. The present study tested the effect of impulsivity on affective responses to an environmental smoking cue. Adult smokers (N = 62) were exposed to a neutral cue and a smoking cue in separate experimental sessions in a repeated measures design. Mixed-effects regression analyses showed that larger postexposure increases in negative affect were associated with high scores on 2 facets …

Forgetting The Once-Seen Face: Estimating The Strength Of An Eyewitness’S Memory Representation, Kenneth A. Deffenbacher, Brian H. Bornstein, E. Kiernan Mcgorty, Steven D. Penrod

Department of Psychology: Faculty Publications

The fidelity of an eyewitness’s memory representation is an issue of paramount forensic concern. Psychological science has been un¬able to offer more than vague generalities concerning the relation of retention interval to memory trace strength for the once-seen face. A meta-analysis of 53 facial memory studies produced a highly reliable association (r = .18, d = 0.37) between longer retention intervals and positive forgetting of once-seen faces, an effect equally strong for both face recognition and eyewitness identification studies. W. A. Wick¬elgren’s (1974, 1975, 1977) theory of recognition memory provided statistically satisfactory fits to 11 different empirical forgetting func¬tions. Applied …

Procedural Justice In Family Conflict Resolution And Deviant Peer Group Involvement Among Adolescents: The Mediating Influence Of Peer Conflict, Jennifer Stuart, Mark Fondarco, Scott A. Miller, Veda Brown, Eve M. Brank

Department of Psychology: Faculty Publications

The involvement of adolescents with deviant peer groups is one of the strongest proximal correlates to juvenile delinquency and stems from a variety of causes. Past research has linked ineffective parenting with peer variables, including deviant peer group involvement and peer conflict during adolescence. In this study, adolescents’ appraisals of procedural justice within the family (adolescents’ appraisals of how fairly they are treated by parents in the process of resolving family conflict) were examined as one aspect of effective parenting that may relate to deviant peer group involvement in early adolescence. Data from 1660 middle school students (ages 11-14, mean …

Role Of Affective Associations In The Planning And Habit Systems Of Decision-Making Related To Addiction, Marc T. Kiviniemi, Rick A. Bevins

Department of Psychology: Faculty Publications

The model proposed by Redish et al. considers vulnerabilities within decision systems based on expectancy-value assumptions. Further understanding of processes leading to addiction can be gained by considering other inputs to decision-making, particularly affective associations with behaviors. This consideration suggests additional decision-making vulnerabilities that might explain addictive behaviors.

A Longitudinal Examination Of The Bidirectional Links Between Academic Achievement And Parent-Adolescent Conflict, Aryn M. Dotterer, Lesa Hoffman, Ann C, Crouter, Susan M. Mchale

Department of Psychology: Faculty Publications

We examined reciprocal associations between parent-adolescent conflict and academic achievement over a 2-year period. Participants were mothers, fathers, and adolescents from predominantly White, working and middle class families (N = 168). After accounting for previous academic achievement, parent-adolescent conflict predicted relative declines in academic achievement 2 years later. After controlling for relationship quality at Time 1, lower math grades predicted relative increases in parent-adolescent conflict 2 years later among families with less education.

Generalizing The Dynamic Field Theory Of Spatial Cognition Across Real And Developmental Time Scales, Vanessa R. Simmering, John P. Spencer, Anne R. Schutte

Department of Psychology: Faculty Publications

Within cognitive neuroscience, computational models are designed to provide insights into the organization of behavior while adhering to neural principles. These models should provide sufficient specificity to generate novel predictions while maintaining the generality needed to capture behavior across tasks and/or time scales. This paper presents one such model, the Dynamic Field Theory (DFT) of spatial cognition, showing new simulations that provide a demonstration proof that the theory generalizes across developmental changes in performance in four tasks—the Piagetian A-not-B task, a sandbox version of the A-not-B task, a canonical spatial recall task, and a position discrimination task. Model simulations demonstrate …

Patience, Jeffrey R. Stevens, David W. Stephens

Department of Psychology: Faculty Publications

What is patience? Humans and other animals often make decisions that trade off present and future benefits. Should a monkey eat an unripe fruit or wait for it to ripen? Should I purchase the iPhone at its debut or wait for the price to drop in a few months? In these dilemmas, large gains often require long waits, so decision makers must choose between a smaller, sooner reward and a larger, later reward.

It sometimes makes sense to choose the smaller, sooner alternative, for example in a very rich environment, but in many natural situations, waiting for the larger, later …

Individual Decision Making And The Evolutionary Roots Of Institutions, Richard Mcelreath, Robert Boyd, Gerd Gigerenzer, Andreas Glöckner, Peter Hammerstein, Robert Kurzban, Stefan Magen, Peter J. Richerson, Arthur Robson, Jeffrey R. Stevens

Department of Psychology: Faculty Publications

Just as many aspects of individual decisions are sometimes called "unconscious" or "automatic," we know that some institutions have evolved through "unconscious," nondeliberative mechanisms. Their function can also be largely nondeliberative, as in the case of some institutions that may structure behavior without requiring any reflection on the part of the participants. On the other hand, political institutions exist for the purpose of bringing deliberative mechanisms to bear on institutions in the hope of changing them for the better. The immense project of building an integrated explanation of institutions from individual brains to nations-has only barely begun. In this chapter, …

A Fruit In The Hand Or Two In The Bush? Divergent Risk Preferences In Chimpanzees And Bonobos, Sarah R. Heilbronner, Alexandra G. Rosati, Jeffrey R. Stevens, Brian Hare, Marc D. Hauser

Department of Psychology: Faculty Publications

Human and non-human animals tend to avoid risky prospects. If such patterns of economic choice are adaptive, risk preferences should reflect the typical decision-making environments faced by organisms. However, this approach has not been widely used to examine the risk sensitivity in closely related species with different ecologies. Here, we experimentally examined risk-sensitive behavior in chimpanzees (Pan troglodytes) and bonobos (Pan paniscus), closely related species whose distinct ecologies are thought to be the major selective force shaping their unique behavioral repertoires. Because chimpanzees exploit riskier food sources in the wild, we predicted that they would exhibit …

Getting Ready: Promoting School Readiness Through A Relationship-Based Partnership Model, Susan M. Sheridan, Christine Marvin, Lisa Knoche, Carolyn P. Edwards

Department of Psychology: Faculty Publications

School readiness is determined by the life experiences of young children between birth and enrollment in formal education programs. Early intervention and education programs designed to promote school readiness often focus on skills a child fails to demonstrate that are believed to be of importance to social and academic success. The Getting Ready model of early childhood intervention (Sheridan, Edwards, & Knoche, 2003) recognizes the transactional nature of young children’s development and the important role parents play in pre-school readiness and school-age success. In the Getting Ready model, collaborative partnerships between parents and professionals are encouraged to promote parent’s competence …

Predictors Of Goggle Use Among Racquetball Players, Carmen P. Mclean, David K. Dilillo, Brian H. Bornstein, R. V. Bevini

Department of Psychology: Faculty Publications

Racquetball is a popular, high-intensity competitive sport that requires quick reflexes and keen spatial awareness. Players may be vulnerable to eye injuries, which could be prevented through use of proper protective eyewear (Feigelman, Sugar, Jednock, Read, & Johnson, 1983). Given the low rates of goggle use among squash players (Eime, Owen, & Finch, 2004), the use of goggles among racquetball players is suspected to be low. However, to date there have been no studies investigating predictors of goggle use in racquetball players. Understanding the rates and predictors of goggle use among racquetball players is an important prerequisite to developing effective …

Enterobius Vermicularis Ancient Dna In Pre-Columbian Human Populations, Alena Mayo Iniguez, Karl J. Reinhard, Luiz Fernando Ferreira, Adauto Araujo, Ana Carolina, Paulo Vincente

Karl Reinhard Publications

In prehistoric populations the paleoparasitological findings show an Enterobius vennicularis homogeneous distribution among North American hunter-gatherers intensified with the advent of agriculture. The same occurred in the transition from nomad hunter-gatherers to sedentary farmers in South America, although E. vermicularis infection encompasses only the ancient Andean peoples. Since molecular techniques are sensitive in detecting ancient DNA (aDNA), in this work we have performed a molecular paleoparasitological study of E. vermicularis. aDNA was recovered from North and South American coprolites (4110 BC-AD 900). Human (cox 2 and HVR) and pinworm (5S rRNA spacer) sequences were determined. The sequence analysis confirmed E. …

Oral Immunization Of Rhesus Macaques With Adenoviral Hiv Vaccines Using Enteric-Coated Capsules, George T. Mercier, Pramod N. Nehete, Marco F. Passeri, Bharti N. Nehete, Eric A. Weaver, Nancy Smyth Templeton, Kimberly Schluns, Stephanie S. Buchl, K. Buchl, Michael A. Barry

Nebraska Center for Virology: Faculty Publications

Targeted delivery of vaccine candidates to the gastrointestinal (GI) tract holds potential for mucosal immunization, particularly against mucosal pathogens like the human immunodeficiency virus (HIV). Among the different strategies for achieving targeted release in the GI tract, namely the small intestine, pH sensitive enteric coating polymers have been shown to protect solid oral dosage forms from the harsh digestive environment of the stomach and dissolve relatively rapidly in the small intestine by taking advantage of the luminal pH gradient. We developed an enteric polymethacrylate formulation for coating hydroxy-propyl-methyl-cellulose (HPMC) capsules containing lyophilized Adenoviral type 5 (Ad5) vectors expressing HIV-1 gag …

Reduced Intestinal Colonization Of Adult Beef Cattle By Escherichia Coli O157:H7 Tir Deletion And Nalidixic-Acid-Resistant Mutants Lacking Flagellar Expression, Gustavo Bretschneider, Emil M. Berberov, Rodney A. Moxley

School of Veterinary and Biomedical Sciences: Faculty Publications

The importance of the Escherichia coli O157:H7 translocated intimin receptor (Tir) protein in intestinal colonization and the effect of infection with Tir⁺ strains on protection against subsequent challenge was studied in adult beef cattle. Cattle were orally inoculated (C1) with a Shiga toxin-2⁺+ E. coli O157:H7 strain that was Tir⁺ or Tir^-, and 42 days later were re-challenged (C2) with the nalidixic acid (Nal) ^R parent strain to test whether prior infection had any effect on fecal shedding. During the first 14 days post-C1, the Nal^S wildtype (WT) strain was shed at significantly …

Infl Uence Of Nicotine On Positive Affect In Anhedonic Smokers, Jessica Werth Cook, Bonnie Spring, Dennis E. Mcchargue

Department of Psychology: Faculty Publications

Rationale – The possibility that individuals administer nicotine to self-regulate persistent negative affect has received interest as a possible explanation for the high prevalence of affectively vulnerable smokers. Relatively overlooked, however, is the possibility that smokers might also self-administer nicotine to elevate low positive affect. Objectives – This study examined whether nicotine administration augmented anhedonic smokers’ positive affective response to a positive mood induction. Materials and methods – Fifty regular smokers (50% female) underwent two positive mood inductions during which they smoked either a nicotinized or denicotinized cigarette in counterbalanced order. Positive affect was assessed before and at two time …

Porcine Intestinal Epithelial Cell Lines As A New In Vitro Model For Studying Adherence And Pathogenesis Of Enterotoxigenic Escherichia Coli, Seung Y. Koh, Sajan George, Volker Brozel, Rodney A. Moxley, David H. Francis, Radhey Kaushik

School of Veterinary and Biomedical Sciences: Faculty Publications

Enterotoxigenic Escherichia coli (ETEC) infections result in large economic losses in the swine industry worldwide. The organism causes diarrhea by adhering to and colonizing enterocytes in the small intestines. While much progress has been made in understanding the pathogenesis of ETEC, no homologous intestinal epithelial cultures suitable for studying porcine ETEC pathogenesis have been described prior to this report. In the current study, we investigated the adherence of various porcine ETEC strains to two porcine (IPEC-1 and IPEC-J2) and one human (INT-407) small intestinal epithelial cell lines. Each cell line was assessed for its ability to support the adherence of …

Light-Evoked Calcium Responses Of Isolated Melanopsin- Expressing Retinal Ganglion Cells, Andrew T. E. Hartwick, Jayne R. Bramley, Jianing Yu, Kelly T. Stevens, Charles N. Allen, William H. Baldridge, Patricia J. Sollars, Gary E. Pickard

School of Veterinary and Biomedical Sciences: Faculty Publications

A small number (<2%) of mammalian retinal ganglion cells express the photopigment melanopsin and are intrinsically photosensitive (ipRGCs). Light depolarizes ipRGCs and increases intracellular calcium levels ( [Ca²⁺]_i ) but the signaling cascades underlying these responses have yet to be elucidated. To facilitate physiological studies on these rare photoreceptors, highly enriched ipRGC cultures from neonatal rats were generated using anti-melanopsin-mediated plate adhesion (immunopanning). This novel approach enabled experiments on isolated ipRGCs, eliminating the potential confounding influence of rod/cone-driven input. Light induced a rise in [Ca²⁺]_i (monitored using fura-2 imaging) in the immunopanned ipRGCs and the source of this Ca²⁺ signal was investigated. The Ca²⁺ responses were inhibited by 2-aminoethoxydiphenyl borate, SKF-96365 (1–2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl-1H-imidazole), flufenamic acid, …

Stable Cell Lines Expressing High Levels Of The Herpes Simplex Virus Type 1 Lat Are Refractory To Caspase 3 Activation And Dna Laddering Following Cold Shock Induced Apoptosis, Dale Carpenter, Chinhui Hsiang, Donald J. Brown, Ling Jin, Nelson Osorio, Lbachir Benmohamed, Clinton J. Jones, Steven L. Wechsler

School of Veterinary and Biomedical Sciences: Faculty Publications

The herpes simplex virus type 1 (HSV-1) latency associated transcript (LAT) gene’s anti-apoptosis activity plays a central, but not fully elucidated, role in enhancing the virus’s reactivation phenotype. In transient transfection experiments, LAT increases cell survival following an apoptotic insult in the absence of other HSV-1 genes. However, the high background of untransfected cells has made it difficult to demonstrate that LAT inhibits specific apoptotic factors such as caspases. Here we report that, in mouse neuroblastoma cell lines (C1300) stably expressing high levels of LAT, cold shock induced apoptosis was blocked as judged by increased survival, protection against DNA fragmentation …

Child Sexual Abuse, Andrea R. Perry, David K. Dilillo

Department of Psychology: Faculty Publications

Child sexual abuse (CSA), a social problem of endemic proportions, has existed in all historical eras and societies (Conte 1994; Fergusson and Mullen 1999; Wekerle and Wolfe 1996; Wolfe 1999). Since antiquity, anecdotal records (e.g., legal, artistic, philosophical, and literary accounts) have documented activities that would today be classified as CSA (deMause 1974; Kahr 1991; Olafson, Corwin, and Summit 1993). For instance, a sizable portion of adults in ancient Greek and Roman cultures openly engaged in what is now considered pederasty or rape (deMause 1974; Kahr 1991). Although adult-child sexual encounters have occurred throughout history, perceptions of such practices have …

Child Maltreatment History And Subsequent Romantic Relationships: Exploring A Psychological Route To Dyadic Difficulties, David K. Dilillo, Terri Lewis, Andrea Di Loreto-Colgan

Department of Psychology: Faculty Publications

A sample of 174 college students involved in heterosexual dating relationships was studied lo investigate the role of psychological distress in mediating links between child maltreatment (CM) history and current couple functioning. Females, but not males, with a history of CM reported greater levels of psychological and relationship difficulties than did non-maltreated women. Psychological distress among females was also found to mediate associations between abuse history and various aspects of couple functioning including intimacy, sexuality. and conflict resolution. No such relationships were found for males. The implications of these results and suggestions for future research are discussed.

Book Review: Using Psychology To Make A Difference, Brian H. Bornstein

Department of Psychology: Faculty Publications

This is a book whose time has come. It collects papers presented at a symposium on applied psychology held at Claremont Graduate University, and that is fitting, as Claremont has one of the leading programs in applied psychology. Most of the chapter authors (8 of 15) are themselves Claremont faculty, and the editors have also gathered a number of impressive outside contributors, such as Philip Zimbardo, Albert Bandura, Robert Rosenthal, Diane Halpern, Stanley Sue, and Elizabeth Loft us. What all these individuals have in common is an interest in using psychology to better the human condition and, in the words …

Negative Mood Regulation Mediates The Relationship Between Distraction And Engagement In Pleasurable Activities Among College Smokers, Lee M. Cohen, Dennis E. Mcchargue, Holly E. R. Morrell

Department of Psychology: Faculty Publications

Smoking for negative mood alleviation is a strong predictor of early smoking and early dependence among undergraduates. Little is known about whether adaptive cognitive coping processes (e.g., distraction) may help decrease the likelihood of student smoking for negative mood regulation. The present study tested the hypothesis that distraction would predict (a) greater engagement in adaptive pleasant pastimes and (b) lower rates of smoking behavior among undergraduates (n = 162, 41.9% female). We further assessed whether negative mood regulation expectations would explain both relationships. Results indicated that negative mood regulation fully mediated the relationship between distraction and engagement in pleasurable …

The Fine Line Of Perfectionism: Is It A Strength Or A Weakness In The Workplace?, Lindsay Bousman

Department of Psychology: Dissertations, Theses, and Student Research

Perfectionism has been traditionally researched in the clinical psychology domain. While some research has used a normal student population, research applying perfectionism theories to a normal adult population working in Corporate America has not been conducted. Current research suggests two distinct types of perfectionism, maladaptive and adaptive, with different consequences. In this research, maladaptive and adaptive perfectionism were used to determine that traditional perfectionism measures can be used with a working adult sample to achieve similar psychometric properties, and to preliminarily test hypotheses related to their relationship with other individual difference variables. Second, maladaptive and adaptive perfectionism were used to …

Using Confirmatory Factor Analysis To Understand Executive Control In Preschool Children: I. Latent Structure, S. A. Wiebe, K. A. Espy, D. Charak

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

Although many tasks have been developed recently to study executive control in the preschool years, the constructs that underlie performance on these tasks are poorly understood. In particular, it is unclear whether executive control is comprised of multiple, separable cognitive abilities (e.g., inhibition and working memory) or whether it is unitary in nature. A sample of 243 normally developing children between 2.25 and 6 years of age completed a battery of age appropriate executive control tasks. Confirmatory factor analysis (CFA) was used to compare multiple models of executive control empirically. A single-factor, general model was sufficient to account for the …

Perinatal Ph And Neuropsychological Outcomes At Age 3 Years In Children Born Preterm: An Exploratory Study, Kimberly A. Espy, Theresa E. Senn, David A. Charak, Jill Tyler, Sandra A. Wiebe

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

The impact of extreme prematurity and related hypoxic-ischemic events on brain development recently has begun to be characterized with modern neuroimaging methods, although comparatively less is known about the neuropathology in those born at heavier birth weights. Even subclinical levels of perinatal hypoxia-ischemia, as indexed by perinatal blood pH, are related to intelligence in school-aged children born preterm. Given the impact of hypoxia-ischemia on white matter and the emerging evidence of specific executive and mathematic deficits in children born preterm, the impact of perinatal hypoxia-ischemia on these outcomes was explored in children at relatively low-risk for sequelae. In a sample …

A Bayesian Multilevel Modeling Approach For Data Query In Wireless Sensor Networks, H. Wang, H. Fang, K. A. Espy, D. Peng, H. Sharif

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

In power-limited Wireless Sensor Network (WSN), it is important to reduce the communication load in order to achieve energy savings. This paper applies a novel statistic method to estimate the parameters based on the realtime data measured by local sensors. Instead of transmitting large real-time data, we proposed to transmit the small amount of dynamic parameters by exploiting both temporal and spatial correlation within and between sensor clusters. The temporal correlation is built on the level-1 Bayesian model at each sensor to predict local readings. Each local sensor transmits their local parameters learned from historical measurement data to their cluster …

Gene Family Encoding The Major Toxins Of Lethal Amanita Mushrooms, Heather E. Hallen-Adams, Hong Luo, John S. Scott-Craig, Jonathan D. Walton

Heather Hallen-Adams Publications

Amatoxins, the lethal constituents of poisonous mushrooms in the genus Amanita, are bicyclic octapeptides. Two genes in A. bisporigera, AMA1 and PHA1, directly encode α-amanitin, an amatoxin, and the related bicyclic heptapeptide phallacidin, a phallotoxin, indicating that these compounds are synthesized on ribosomes and not by nonribosomal peptide synthetases. α-Amanitin and phallacidin are synthesized as proproteins of 35 and 34 amino acids, respectively, from which they are predicted to be cleaved by a prolyl oligopeptidase. AMA1 and PHA1 are present in other toxic species of Amanita section Phalloidae but are absent from nontoxic species in other sections. …

Fluoxetine, Smoking, And History Of Major Depression: A Randomized Controlled Trial, Bonnie Spring, Neal Doran, Sherry Pagoto, Dennis E. Mcchargue, Jessica Werth Cook, Katherine Bailey, John Crayton, Donald Hedecker

Department of Psychology: Faculty Publications

The study was a randomized placebo-controlled trial testing whether fluoxetine selectively enhances cessation for smokers with a history of depression. Euthymic smokers with (H+, n = 109) or without (H-, n = 138) a history of major depression received 60 mg fluoxetine or placebo plus group behavioral quit-smoking treatment for 12 weeks. Fluoxetine initially enhanced cessation for H+ smokers (p = .02) but subsequently impaired cessation regardless of depressive history. Six months after quit date, fluoxetine-treated participants were 3.3 times more likely to be smoking (p = .02). Further research is warranted to determine why high-dose fluoxetine produces …

2006 Michigan Dairy Farm Business Analysis Summary, Eric Wittenberg, Christopher Wolf

Michigan Bovine Tuberculosis Bibliography and Database

This report summarizes the financial and production records of 139 dairy farms from throughout Michigan in 2006. To be included, the farms must have produced at least 50 percent of gross cash farm income from milk and dairy animal sales. The records came from Michigan State University’s TelFarm project and the Farm Credit Service system in Michigan. The values were pooled into averages for reporting purposes. The farms are larger than would be the average of all dairy farms in Michigan. While considerable variation in the data exists, average values are reported in the summary tables and discussion that follows.

Differences In Virulence Among Escherichia Coli O157:H7 Strains Isolated From Humans During Disease Outbreaks And From Healthy Cattle, Diane R. Baker, Rodney A. Moxley, Mike B. Steele, Jeffrey T. Lejeune, Jane Christopher-Hennings, Ding-Geng Chen, Philip R. Hardwidge, David H. Francis

School of Veterinary and Biomedical Sciences: Faculty Publications

Escherichia coli O157:H7 causes life-threatening outbreaks of diarrhea, hemorrhagic colitis, and hemolyticuremic syndrome in humans and significant economic loss in agriculture and could be a potential agent of bioterrorism. Although the prevalence of E. coli O157:H7 in cattle and other species with which humans have frequent contact is high, human infections are relatively uncommon, despite a low infectious dose. A plausible explanation for the low disease incidence is the possibility that not all strains are virulent in humans. If there are substantial differences in virulence among strains in nature, then human disease may select for high virulence. We used a …