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Articles 2101 - 2130 of 5204
Full-Text Articles in Medicine and Health Sciences
Networking With Researchers And Farmers To Tackle Herbicide-Resistant Weeds, Melinda K. Yerka
Networking With Researchers And Farmers To Tackle Herbicide-Resistant Weeds, Melinda K. Yerka
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
Outline •Crop breeding technology •Regulation of crop technologies •Issues related to crop-to-weed gene flow •Need for landscape-level studies
GMO •Genetically Modified Organism •Most commercial traits facilitate crop production –Insect resistance (Btcorn) –Herbicide resistance (Roundup) •General scientific consensus that they are safe •Public concerns persist
GM…..Oh? •GMOs are regulated substances by USDA-APHIS –$80 to $150 million per genotype to get to market •USDA-APHIS: Which biotech traits do we regulate? •Commodity groups: Will we be regulated???
The special case of sorghum: Massive international development as a biofuel •Better drought tolerance than corn •Needs herbicide resistance to compete
Evolution of herbicide resistance in …
Why We Need To Help Youth Develop A Stem Identity, Saundra Frerichs
Why We Need To Help Youth Develop A Stem Identity, Saundra Frerichs
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
Favorite Toys
Developing Identity
Click 2 Science http://click2sciencepd.org
click2sciencepd.org
@Click2Science
Training Undergraduates To Sell It: #Scicomm In An Ecology Course, Teresa Bilinski
Training Undergraduates To Sell It: #Scicomm In An Ecology Course, Teresa Bilinski
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
Stop. Being. Boring.
Science: Soft Skill? No.
Essential Transferable Skill: “Students would be better served by an education that is integrated with the job market they will encounter post-graduation, and one that provides not only technical skills but also the soft skills that are most in demand by employers such as communication…”
#SciCommin a senior Ecology course: Course-based undergraduate research experience (CURE). Ecosystem services at the wildland-urban interface: involving undergraduates in ecological investigations
Pre- assignment “Summarize the Results of an ecological research project related to the effects of urbanization on ecosystems. The research summaries will be presented orally to the …
The Engineering Ambassadors Network: Engaging Undergraduate Engineers In P-12 Outreach, Sally Wei
The Engineering Ambassadors Network: Engaging Undergraduate Engineers In P-12 Outreach, Sally Wei
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
In the next few minutes I want to focus your attention on the T and E of STEM. Take a few seconds and think about what in this room is either not engineering and tech itself or does not have any interface with engineering and tech.
So engineering is ubiquitous, how do we teach this across society particularly P12 and how do we create the pipeline?
The Engineering Ambassadors Network is a nationwide network of colleges and universities designed to change the conversation on engineering.
EAN’s mission is two‐fold: to develop engineering leaders as well as impact P‐12 engineering education. …
How To Be A Biologist?, Fernando Mateos-González
How To Be A Biologist?, Fernando Mateos-González
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
http://www.bioblogia.net/p/consejosjovenesbiologos.html
Tips for young biologists-- •How and why study Biology •How to get experience, contacts, and jobs as a biologist •My own troubles/experiences
What do they ask about?
My own goals for SciComm2016…
Science Communication Strategies In The K-12 Classroom, Andrew Ising
Science Communication Strategies In The K-12 Classroom, Andrew Ising
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
@ItsIsing
andrewising@gmail
KABT.org #SciComm2016
bit.ly/isingnsc
Why is science literacy important to you? Why is science literacy important to me?
Situation #1: Peer Review -- Scientists talking to other Scientists; Making Science Research More Accessible: Poster Sessions [KABT Miniposters]
Situation #2: Informal Science -- Scientists telling science stories Common sources: Blogs, science magazines, newspapers, etc. Documentaries Social Media Why students like this: Narrative… Drama… Fewer long latin words
Situation #3: Community Outreach -- Scientists talking as experts to an audience “A scientist seen is a scientist trusted” Be/Become someone’s “BROADER IMPACTS”! Citizen Science Projects (Scistarter, YourWildLife, IMP, Great KS Tardigrade Hunt, …
Eight-Legged Encounters: Using Organismal Biology To Bring Science Education To Families & Communities, Eileen A. Hebets
Eight-Legged Encounters: Using Organismal Biology To Bring Science Education To Families & Communities, Eileen A. Hebets
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
Path of the Predators: A Journey Through the Living Arachnids. Illustrations by Pawl Tisdale
WHAT IS AN ARTHROPOD?
CREATE A CHELICERATE
ASSEMBLE AN ARACHNID
TISSUE PAPER FLOWER
MICROSCOPE MADNESS
Eight-Legged Encounters Impact
Change in interest in learning about scientific discoveries among adult respondents (n = 63).
Youth’s interest in science activities (n = 42). Respondents were 50% female, 50% male and ranged in age from 4 – 14 with a mean of 7.7.
Building Educator Capacity To Address Animal Agriculture In A Changing Climate, Crystal Powers
Building Educator Capacity To Address Animal Agriculture In A Changing Climate, Crystal Powers
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
Multi-Regional Approach.
Project Support.
Project Objectives • Equip Educators –ability & motivation • Provide science-based information • Coordinate state, regional and national levels.
Online Course. Outcomes -ability. Outcomes -motivation.
Understand worldviews. Meet people where they are. Start with local history.
Framing: Focus on audience’s values & concerns. Present new information so it can be heard
Science in Action: • Public wants to know how the science applies to their life. • We can point back to the basic science
SciComm Lessons Learned
Engineering Empowerment: Science Literacy Through Engineering Design, Jennifer R. Keshwani
Engineering Empowerment: Science Literacy Through Engineering Design, Jennifer R. Keshwani
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
Outcome A scientifically literate society capable of making effective decisions grounded in STEMinformed analyses of complex, real‐world challenges associated with food, fuel, water, landscape, and people issues.
Finding Solutions for Life on a Small Planet
Produce future STEM professionals
Develop a science and technology literate society
K-12 Engineering: Exposure to Engineering Design; K‐12 Engineering Design Curricula; Undergrad Teaching Experience; K‐12 Educator Professional Development
The Role Of Design Thinking In Scientific Research & Communication, Colleen Syron
The Role Of Design Thinking In Scientific Research & Communication, Colleen Syron
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
Design thnking: Research: • Interviews with designers • Observations and case studies • Experimental studies • Simulation • Reflection and theorizing
Designing is not a search for the optimum solution to the given problem, but that it is an exploratory process. The creative designer interprets the design brief not as a specification for a solution, but as a starting point for a journey of exploration,…
“Deduction proves that something must be; Induction shows that something actually is operative; Abduction suggests that something may be.” Charles Pierce
The main point of difference is that of timing. Both artists and scientists operate …
Public Perceptions Of Drones Used For Weather-Related Purposes, Lisa M. Pytlikzillig, Janell C. Walther, Carrick Detweiler, Adam L. Houston
Public Perceptions Of Drones Used For Weather-Related Purposes, Lisa M. Pytlikzillig, Janell C. Walther, Carrick Detweiler, Adam L. Houston
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
The CLOUDMAP Team -- Collaboration Leading Operational UAS Development for Meteorology and Atmospheric Physics. An EPSCOR grant funded by NSF
Responsible Innovation & Trust
Public Perception Studies to Date
Some Major Findings • You can call a drone whatever you want without changing people’s support • Purpose matters • Trust matters…
And More Findings • Sensemaking through pop culture, lack of knowledge, questioning, and purpose. • Hopes for societal benefits such as research technology and improved public safety (reduced risk, better forecasting). • Concerns for privacy, public & airspace safety, and pollution. • Recommendations for collaborative regulation creation for safety …
You Kan: A Graduate Student Perspective On K-12 Outreach In Ks, Nicole Green
You Kan: A Graduate Student Perspective On K-12 Outreach In Ks, Nicole Green
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
Science gets interesting at interfaces.
K-12 Outreach in Kansas:
NSF GK-12 EIDROP Fellow (2014-2015) #0841414 Partnership with USD 475 ‘Resident Scientist’, AP Biology
EXCITE! Summer Workshop Series (2015, 2016) KAWSE Office ‘Drosophi-what? Using Fruit Flies as a Biological Model Organism’, 9th-12th grades
4-H SPecial INterest (SPIN) Fall 2015-Spring 2016 After school programming with USD 383, 2nd-5thgrades
Camp R.O.A.R. (Real Observation ARoundUs), Lincoln Elementary School, K-5th grades, funded by ASCB COMPASS Outreach grant
Engaging in outreach is a unique graduate training experience. Successful outreach programs meet students where they are.
If you walk into the classroom with good intentions and a …
Structural Diversity In The Type Iv Pili Of Multidrug-Resistant Acinetobacter, Kurt H. Piepenbrink, Erik Lillehoj, Christian M. Harding, Jason W. Labonte, Xiaotong Zuo, Chelsea A. Rapp, Robert S. Munson Jr, Simeon E. Goldblum, Mario F. Feldman, Jeffrey J. Gray, Eric J. Sundberg
Structural Diversity In The Type Iv Pili Of Multidrug-Resistant Acinetobacter, Kurt H. Piepenbrink, Erik Lillehoj, Christian M. Harding, Jason W. Labonte, Xiaotong Zuo, Chelsea A. Rapp, Robert S. Munson Jr, Simeon E. Goldblum, Mario F. Feldman, Jeffrey J. Gray, Eric J. Sundberg
Food for Health: Publications
Acinetobacter baumannii is a Gram-negative coccobacillus found primarily in hospital settings that has recently emerged as a source of hospital-acquired infections. A. baumannii expresses a variety of virulence factors, including type IV pili, bacterial extracellular appendages often essential for attachment to host cells. Here, we report the high resolution structures of the major pilin subunit, PilA, from three Acinetobacter strains, demonstrating thatA. baumannii subsets produce morphologically distinct type IV pilin glycoproteins. We examine the consequences of this heterogeneity for protein folding and assembly as well as host-cell adhesion by Acinetobacter. Comparisons of genomic and structural data with pilin proteins from …
Temporal And Spatial Distribution Of Enterobius Vermicularis (Nematoda: Oxyuridae) In The Prehistoric Americas, Karl J. Reinhard, Adauto Araújo, Johnica J. Morrow
Temporal And Spatial Distribution Of Enterobius Vermicularis (Nematoda: Oxyuridae) In The Prehistoric Americas, Karl J. Reinhard, Adauto Araújo, Johnica J. Morrow
Karl Reinhard Publications
Investigations of Enterobius sp. infection in prehistory have produced a body of data that can be used to evaluate the geographic distribution of infection through time in the Americas. Regional variations in prevalence are evident. In North America, 119 pinworm positive samples were found in 1,112 samples from 28 sites with a prevalence of 10.7%. Almost all of the positive samples came from agricultural sites. From Brazil, 0 pinworm positive samples were found in 325 samples from 7 sites. For the Andes region, 22 pinworm positive samples were found in 411 samples from 26 sites for a prevalence of 5.3%. …
Nonmetropolitan Nebraskans’ Perceptions Of Local Schools: 2016 Nebraska Rural Poll Results, Rebecca J. Vogt, Cheryl A. Burkhart-Kriesel, Randolph L. Cantrell, Bradley Lubben, L.J. Mcelravy, Jeanne Lorraine Surface
Nonmetropolitan Nebraskans’ Perceptions Of Local Schools: 2016 Nebraska Rural Poll Results, Rebecca J. Vogt, Cheryl A. Burkhart-Kriesel, Randolph L. Cantrell, Bradley Lubben, L.J. Mcelravy, Jeanne Lorraine Surface
Rural Futures Institute: Publications
Conclusion
Most rural Nebraskans have elementary, middle and high schools in their community or nearest community. Most of the schools available are public but many rural Nebraskans report having both public and private schools of each grade level. Persons living in or near larger communities are more likely than persons living in or near smaller communities to have each level of school in their community. And, persons living in or near the larger communities are more likely than persons living in or near smaller communities to have both public and private schools available.
When asked about priorities for their local …
The Neu1-Selective Sialidase Inhibitor, C9- Butyl-Amide-Dana, Blocks Sialidase Activity And Neu1-Mediated Bioactivities In Human Lung In Vitro And Murine Lung In Vivo, Sang W. Hyun, Anguo Liu, Zhenguo Liu, Alan S. Cross, Avelino C. Verceles, Sadagopan Magesh, Yadagiri Kommagalla, Chandrababunaidu Kona, Hiromune Ando, Irina G. Luzina, Sergei P. Atamas, Kurt H. Piepenbrink, Eric J. Sundberg, Wei Guang, Hideharu Ishida, Erik P. Lillehoj, Simeon E. Goldblum
The Neu1-Selective Sialidase Inhibitor, C9- Butyl-Amide-Dana, Blocks Sialidase Activity And Neu1-Mediated Bioactivities In Human Lung In Vitro And Murine Lung In Vivo, Sang W. Hyun, Anguo Liu, Zhenguo Liu, Alan S. Cross, Avelino C. Verceles, Sadagopan Magesh, Yadagiri Kommagalla, Chandrababunaidu Kona, Hiromune Ando, Irina G. Luzina, Sergei P. Atamas, Kurt H. Piepenbrink, Eric J. Sundberg, Wei Guang, Hideharu Ishida, Erik P. Lillehoj, Simeon E. Goldblum
Food for Health: Publications
Neuraminidase-1 (NEU1) is the predominant sialidase expressed in human airway epithelia and lung microvascular endothelia where it mediates multiple biological processes. We tested whether the NEU1-selective sialidase inhibitor, C9-butyl-amide-2-deoxy-2,3-dehydro-Nacetylneuraminic acid (C9-BA-DANA), inhibits one or more established NEU1-mediated bioactivities in human lung cells. We established the IC50 values of C9-BA-DANA for total sialidase activity in human airway epithelia, lung microvascular endothelia and lung fibroblasts to be 3.74 µM, 13.0 µM and 4.82 µM, respectively. In human airway epithelia, C9-BA-DANA dose-dependently inhibited flagellin-induced, NEU1-mediated mucin-1 ectodomain desialylation, adhesiveness for Pseudomonas aeruginosa and shedding. In lung microvascular endothelia, C9-BA-DANA reversed NEU1-driven restraint of …
Experimental Infection Of Conventional Nursing Pigs And Their Dams With Porcine Deltacoronavirus, Sarah Vitosh-Sillman, John Dustin Loy, Bruce W. Brodersen, Clayton L. Kelling, Alan R. Doster, Christina L. Topliff, Eric A. Nelson, Jianfa Bai, Erin Schirtzinger, Elizabeth Poulsen, Barbara Meadors, Joseph Anderson, Benjamin Hause, Gary Anderson, Richard Hesse
Experimental Infection Of Conventional Nursing Pigs And Their Dams With Porcine Deltacoronavirus, Sarah Vitosh-Sillman, John Dustin Loy, Bruce W. Brodersen, Clayton L. Kelling, Alan R. Doster, Christina L. Topliff, Eric A. Nelson, Jianfa Bai, Erin Schirtzinger, Elizabeth Poulsen, Barbara Meadors, Joseph Anderson, Benjamin Hause, Gary Anderson, Richard Hesse
School of Veterinary and Biomedical Sciences: Faculty Publications
Porcine deltacoronavirus (PDCoV) is a newly identified virus that has been detected in swine herds of North America associated with enteric disease. The aim of this study was to demonstrate the pathogenicity, course of infection, virus kinetics, and aerosol transmission of PDCoV using 87 conventional piglets and their 9 dams, including aerosol and contact controls to emulate field conditions. Piglets 2–4 days of age and their dams were administered an oronasal PDCoV inoculum with a quantitative real-time reverse transcription (qRT)-PCR quantification cycle (Cq) value of 22 that was generated from a field sample having 100% nucleotide identity to USA/Illinois121/2014 determined …
Neural Control Of Tongue Movements Across Effort Levels, Megan Rovang, Angela M. Dietsch
Neural Control Of Tongue Movements Across Effort Levels, Megan Rovang, Angela M. Dietsch
UCARE: Research Products
Background
A hallmark of Parkinson’s disease (PD) is a mismatch between the perceived effort and actual forces exerted during functional activities such as speech. Current evidence supports therapy to help reset this perception of effort, but the neurological underpinnings of such treatments are unclear. This study examined brain activity during tongue movements performed at varying levels of effort to determine (1) which brain areas are involved in each task, and (2) which areas, if any, scale in activation according to effort level. These results, considered with the neurological changes associated with PD, can be used to develop and refine treatment …
Cleaning Puparia For Forensic Analysis, Leon G. Higley, Tierney R. Brosius, Karl Reinhard, David Carter
Cleaning Puparia For Forensic Analysis, Leon G. Higley, Tierney R. Brosius, Karl Reinhard, David Carter
Karl Reinhard Publications
We tested procedures for removing adipocere from insect samples to allow identification. An acceptable procedure was determined: (i) Samples were sorted in petri dishes with 75% alcohol to remove any larvae, adult insects, or other soft-bodied material. (ii) Samples of up to 24 puparia were placed in a vial with 15 mL of 95% acetone, capped, and vortexed for a total of 30–90 sec in 10- to 15-sec bursts. This step removed large masses of adipocere or soil from specimen. (iii) Specimens were removed from acetone and placed in a vial of 15 mL of 2% potassium hydroxide (KOH) and …
Raising Nebraska: Engaging The Public In Ways That They Value, Chuck Hibberd
Raising Nebraska: Engaging The Public In Ways That They Value, Chuck Hibberd
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
Raising Nebraska A partnership: •Nebraska State Fair •Nebraska Extension •Nebraska Department of Agriculture With a purpose: •Demonstrate the science and art of Nebraska agriculture •Learn from consumers
Prescribing irrigation –conserving water
Walkable Nebraska map -elevation change, waterways, precipitation and crops/livestock
Trusted Voice Videos –Top 5 & Bottom 5
Interactive Dinner Table -- Dinner Table –Entrée, Drink, & Side Selection
Exit Poll -How many things did you learn today?
Conclusions •Participants are telling us what they want to learn more about •Participant responses provide insight on content offerings •Interactive, digitally-based learning venues are effective
Tell Me A Science Story: Transforming Engagement With Science Using Creative Nonfiction, Janell C. Walther
Tell Me A Science Story: Transforming Engagement With Science Using Creative Nonfiction, Janell C. Walther
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
“I definitely felt more engaged with the first one [creative nonfiction]and less tuned out because I had somebody interpreting their response for me. So when he was like “Oh, I was surprised” then I think “Oh, so was I, I was also surprised by the piece of information.” So I was more engaged with it personally even if I didn't retain all the numbers... “
“[The story] seemed more relatable I guess, as a normal, average, everyday person than a whole bunch of scientists talking about facts. Where the facts were still in here, the way that it was written …
Science Not Communicated Is Science Not Done: Present Your Science Powerfully, Melissa Marshall
Science Not Communicated Is Science Not Done: Present Your Science Powerfully, Melissa Marshall
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
Great communication ignites a chain reaction. Discussion: Identify the best presenter of science that you have seen. What made that speaker so effective?
To excel in your presentations, you will need content , passion, and a sharp sense of the audience.
Science not communicated is science not done. Presenting your science powerfully requires mastery of three skills: Be Audience Centered, Filter and focus, Show your science
Becoming an audience focused speaker is one of the most powerful skills you can adopt. Returning to points of common ground satisfies audiences of different technical backgrounds.
Successful technical presentations require you to filter …
How To Talk About Science In The Face Of Religious Mistrust, Clay Farris Naff
How To Talk About Science In The Face Of Religious Mistrust, Clay Farris Naff
SciComm 2016 - Lincoln, Nebraska, September 23-24, 2016
King Ashoka (268to 232 BCE). Ralph Waldo Emerson. Homer Simpson. Us and THEM. Timothy Gay, UNL Prof. of Physics. Ken Miller, Prof. of Biology, Brown. Richard Dawkins. Ken Ham, Answers in Genesis.
THEM = Truthful Humble Evidential Memorable
Theistic Evolution. Human Babies Barely Fit. The right & left laryngeal nerves take wildly differing paths. Progeria. General Theory of Relativity. Sun’s Gravity Bends Starlight. GPS & Relativity. Sugar vs. Fat. U.S. stock market. Pope. Dalai Lama. Epicurus.
The Impact Of Nutrition And Physical Activity Education On The Knowledge, Attitude, And Behavior Of Muslim Youth From Various Ethnic Backgrounds, Hana L. Jaber, Zainab Rida
The Impact Of Nutrition And Physical Activity Education On The Knowledge, Attitude, And Behavior Of Muslim Youth From Various Ethnic Backgrounds, Hana L. Jaber, Zainab Rida
UCARE: Research Products
The Islamic Foundation of Lincoln is a growing population within Lincoln including many different racial backgrounds, ethnic identities, and languages. Due to these various backgrounds communication may impair the education of families as well as their attitudes and behaviors. Although there are programs developed for many other minority groups, the Muslim (population comprising the Islamic Foundation of Lincoln) population does not have any data obtained from the community in terms of nutrition and physical activity behaviors, attitudes, and knowledge. This study seeks to understand if there are barriers to communication and if the intervention enhanced nutrition knowledge. This poster reflects …
Effect Of Taste Stimuli On Swallowing Function In Persons With Traumatic Injuries, Megan Asselin, Angela M. Dietsch
Effect Of Taste Stimuli On Swallowing Function In Persons With Traumatic Injuries, Megan Asselin, Angela M. Dietsch
UCARE: Research Products
Background
Swallowing disorders are prevalent and costly. As of now, there are limited therapeutic options available to treat them. Extant research in limited populations has suggested that swallowing mechanics can be improved by extremely sour liquids, but this has not been tested in traumatically injured populations. However, sour tastants are unpleasant, and more palatable taste mixtures have not been tested.
Methods
The quantitative data were extracted from an existing pool of de-identified video fluoroscopic swallowing studies (moving radiographs) obtained from traumatically injured young adults under another research protocol. Each participant completed swallows of custom-mixed plain, sour, and sweet-sour boluses. Positions …
Whole Genomic Sequence Analysis Of Bacillus Infantis: Defining The Genetic Blueprint Of Strain Nrrl B-14911, An Emerging Cardiopathogenic Microbe, Chandirasegara Massilamany, Akram Mohammed, John Dustin Loy, Tanya Purvis, Bharathi Krishnan, Rakesh H. Basavalingappa, Christy M. Kelley, Chittibabu Guda, Raúl G. Barletta, Etsuko N. Moriyama, Timothy P.L. Smith, Jay Reddy
Whole Genomic Sequence Analysis Of Bacillus Infantis: Defining The Genetic Blueprint Of Strain Nrrl B-14911, An Emerging Cardiopathogenic Microbe, Chandirasegara Massilamany, Akram Mohammed, John Dustin Loy, Tanya Purvis, Bharathi Krishnan, Rakesh H. Basavalingappa, Christy M. Kelley, Chittibabu Guda, Raúl G. Barletta, Etsuko N. Moriyama, Timothy P.L. Smith, Jay Reddy
Jay Reddy Publications
Background: We recently reported the identification of Bacillus sp. NRRL B-14911 that induces heart autoimmunity by generating cardiac-reactive T cells through molecular mimicry. This marine bacterium was originally isolated from the Gulf of Mexico, but no associations with human diseases were reported. Therefore, to characterize its biological and medical significance, we sought to determine and analyze the complete genome sequence of Bacillus sp. NRRL B-14911.
Results: Based on the phylogenetic analysis of 16S ribosomal RNA (rRNA) genes, sequence analysis of the 16S-23S rDNA intergenic transcribed spacers, phenotypic microarray, and matrix-assisted laser desorption ionization time-offlight mass spectrometry, we propose that this …
3-Hydroxy Fatty Acid Induce Trophoblast And Hepatocyte Lipoapoptosis, Taylor Bruett, Taylor Heng, Sathish Kumar Natarajan
3-Hydroxy Fatty Acid Induce Trophoblast And Hepatocyte Lipoapoptosis, Taylor Bruett, Taylor Heng, Sathish Kumar Natarajan
UCARE: Research Products
Acute Fatty Liver of Pregnancy (AFLP) is a very rare and fatal condition for both the mother and the unborn offspring accompanied by severe maternal liver dysfunction. AFLP usually develops during the third trimester of pregnancy with symptoms of liver disease. AFLP is associated with a mutation in the enzyme, long-chain 3-hydroxy acyl CoA dehydrogenase (LCHAD) which is involved in the mitochondrial beta-oxidation of fatty acids. Defective beta-oxidation of fatty acids results in the individual unable to metabolize fatty acids which then causes fatty infiltration in their organs, such as the liver. This interferes with normal function of the liver …
Guidelines For Interpretive Interview Fidelity In Mixed Methods Research Within The Context Of A Randomized Controlled Trial, Amanda L. Garrett
Guidelines For Interpretive Interview Fidelity In Mixed Methods Research Within The Context Of A Randomized Controlled Trial, Amanda L. Garrett
College of Education and Human Sciences: Dissertations, Theses, and Student Research
Interviews fascinate and capture individuals’ attention. Researchers value the data they glean from interviews, while participants enjoy being asked to share their voices and opinions. Some of the most complex, stringent research designs are now being revised to include interviews, such as randomized controlled trials. But, how do we know that the interviews that are conducted are valid? We need to know more about how interviews are developed and delivered within the context of intervention research. Therefore, the aim of this methodological dissertation is to create a set of recommendations for interpretive interviews in a mixed methods randomized controlled trial. …
Icook 4-H Intervention: Food-Related Behavior And Intake Of Adult Main Meal Preparers Participating In A 5-State Childhood Obesity Prevention Study, Kyla A. Richardson
Icook 4-H Intervention: Food-Related Behavior And Intake Of Adult Main Meal Preparers Participating In A 5-State Childhood Obesity Prevention Study, Kyla A. Richardson
Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research
Childhood obesity affects 12.7 million children within the United States. The need for childhood obesity prevention programs is high. Research supports family-centered programs and health interventions rooted within the Social Cognitive Theory (SCT); the iCook 4-H program combines these attributes. The objective of this study was to assess differences in adult outcome variables between control and treatment participants and whether the program impacted food security status.
Participants consisted of adult-youth pairs (dyads) that included a 9-10 year-old child and their adult primary meal preparer. The focus of this project was to provide findings on adult participants only. The program was …
Mucosal Vaccination By Adenoviruses Displaying Reovirus Sigma 1, Eric A. Weaver, Zenaido T. Camacho, Matthew L. Hillestad, Catherine M. Crosby, Mallory A. Turner, Adam J. Guenzel, Hind J. Fadel, George T. Mercier, Michael A. Barry
Mucosal Vaccination By Adenoviruses Displaying Reovirus Sigma 1, Eric A. Weaver, Zenaido T. Camacho, Matthew L. Hillestad, Catherine M. Crosby, Mallory A. Turner, Adam J. Guenzel, Hind J. Fadel, George T. Mercier, Michael A. Barry
Nebraska Center for Virology: Faculty Publications
We previously developed adenovirus serotype 5 (Ad5) vectors displaying the sigma 1 protein from reovirus as mucosal vaccines. Ad5-sigma retargets to JAM-1 and sialic acid, but had 40-fold reduced gene delivery when compared to Ad5. While weaker at transduction, Ad5-sigma generated stronger T cell responses than Ad5 when used for mucosal immunization. New Ad5-fiber-sigma vectors were generated here by varying the number of fiber β-spiral shaft repeats (R) fused between fiber tail and the sigma. Ad5 virions encoding R3, R14, and R20 chimeras were rescued. Increasing chimera length led to their decreasing encapsidation of these proteins in the virions. Ad5-R3 …