Medicine and Health Sciences Commons^™

U.S. Adult Perceptions Of The Harmfulness Of Tobacco Products: Descriptive T Findings From The 2013–14 Baseline Wave 1 Of The Path Study, Geoffrey T. Fong, Tara Elton-Marshall, Pete Driezen, Annette R. Kaufman, K. Michael Cummings, Kelvin Choi, Jonathan Kwan, Amber Koblitz, Andrew Hyland, Maansi Bansal-Travers, Charles Carusi, Mary E. Thompson

United States Food and Drug Administration: Publications

Introduction: This study is the first nationally representative survey of U.S. adults (18+) to examine perceptions of the relative harms of eight non-cigarette tobacco products.

Methods: Data are from Wave 1 of the Population Assessment of Tobacco and Health (PATH) Study Adult Questionnaire, a nationally representative study of 32,320 adults in the United States conducted from September 2013 to December 2014.

Results: 40.7% of adults believed that electronic cigarettes were less harmful than cigarettes, and 17.8% of adults believed that hookah was less harmful than cigarettes. Those less knowledgeable about the health risks of smoking were more likely to believe …

Dynamic Effects Of Habituation And Novelty Detection On Newborn Event Related Potentials, Cathryn S. Cortesa, Caitlin M Hudac, Dennis Molfese

Center for Brain, Biology, and Behavior: Faculty Publications

Newborns habituate to repeated auditory stimuli, and discriminate syllables, generating opportunities for early language learning. This study investigated trial-by-trial changes in newborn electrophysiological responses to auditory speech syllables as an index of habituation and novelty detection. Auditory event-related potentials (ERPs) were recorded from 16 term newborn infants, aged 1–3 days, in response to monosyllabic speech syllables presented during habituation and novelty detection tasks. Multilevel models demonstrated that newborns habituated to repeated auditory syllables, as ERP amplitude attenuated for a late-latency component over successive trials. Subsequently, during the novelty detection task, earlyand late-latency component amplitudes decreased over successive trials for novel …

Concussion Competencies: A Training Model For School-Based Concussion Management, Arthur C. Maerlender, Jonathan D. Lichtenstein, Jennifer Parent-Nichols, Kate Higgins, Peggy Reisher

Center for Brain, Biology, and Behavior: Faculty Publications

This study reports on the use of ten knowledge competencies related to the behavioral management of concussion in schools. Trainings using these competencies as learning objectives were delivered to school personnel. This aims of the use of competencies in this way are to streamline the education of key stakeholders, to establish clear roles and responsibilities for constituents and equip individuals working with students following a concussion with the relevant knowledge to optimize outcomes. The majority of participants, primarily speech language pathologists working as related service providers in the schoolswhere the trainings occurred, judged the use of the competencies to be …

Confirmatory Factor Analysis Of Two Computerized Neuropsychological Test Batteries: Immediate Post-Concussion Assessment And Cognitive Test (Impact) And C3 Logix, Caitlin Masterson, Julie Tuttle, Arthur C. Maerlender

Center for Brain, Biology, and Behavior: Faculty Publications

Introduction: Tests of memory and speed of cognitive and motor responses have been the primary foci in sports-related concussion assessment. This study sought to assess the construct validity of neuropsychological tests within C3 Logix.

Method: Results of both baseline C3 Logix and the Immediate Post-Concussion Assessment and Cognitive Test (ImPACT) computerized tests from 86 Division I collegiate athletes were submitted to a two-factor confirmatory analysis using structural equation modeling. The two factors of Speed and Memory have been confirmed in previous studies of ImPACT.

Results: Results confirmed the two-factor model of ImPACT, whereas C3 Logix did not …

Functional Source Separation For Eeg-Fmri Fusion: Application To Steady-State Visual Evoked Potentials, Hong Ji, Badong Chen, Nathan M. Petro, Zejian Yuan, Nanning Zheng, Andreas Keil

Center for Brain, Biology, and Behavior: Faculty Publications

Neurorobotics is one of the most ambitious fields in robotics, driving integration of interdisciplinary data and knowledge. One of the most productive areas of interdisciplinary research in this area has been the implementation of biologically-inspired mechanisms in the development of autonomous systems. Specifically, enabling such systems to display adaptive behavior such as learning from good and bad outcomes, has been achieved by quantifying and understanding the neural mechanisms of the brain networks mediating adaptive behaviors in humans and animals. For example, associative learning from aversive or dangerous outcomes is crucial for an autonomous system, to avoid dangerous situations in the …

Dr. Seuss Fine Motor Development Club, Nicole Borcyk, Madelyn Beck

Honors Program: Expanded Learning Clubs

After school club that helps students develop fine motor skills by doing hands-on activities relating to Dr. Seuss's most popular books.

Design And Characterization Of A Consensus Hemagglutinin Vaccine Immunogen Against H3 Influenza A Viruses Of Swine, Haiyan Sun, Jung-Hyang Sur, Sarah Vitosh-Sillman, David J. Steffen, Hiep Vu

Nebraska Center for Virology: Faculty Publications

The substantial genetic diversity exhibited by influenza A viruses of swine (IAV-S) represents the main challenge for the development of a broadly protective vaccine against this important pathogen. The consensus vaccine immunogen has proven an effective vaccinology approach to overcome the extraordinary genetic diversity of RNA viruses. In this project, we sought to determine if a consensus IAV-S hemagglutinin (HA) immunogen would elicit broadly protective immunity in pigs. To address this question, a consensus HA gene (designated H3-CON.1) was generated from a set of 1,112 H3 sequences of IAV-S recorded in GenBank from 2011 to 2015. The consensus HA gene …

Reverse Genetics Systems As Tools To Overcome The Genetic Diversity Of Lassa Virus, Brett Beitzel, Christine E. Hulseberg, Gustavo Palacios

United States Army: Publications

Lassa virus is endemic in a large area of sub-Saharan Africa, and exhibits a large amount of genetic diversity. Of the four currently recognized lineages, lineages I–III circulate in Nigeria, and lineage IV circulates in Sierra Leone, Guinea, and Liberia. However, several newly detected lineages have been proposed. LASV genetic diversity may result in differences in pathogenicity or response to medical countermeasures, necessitating the testing of multiple lineages during the development of countermeasures and diagnostics. Logistical and biosafety concerns can make it difficult to obtain representative collections of divergent LASV clades for comparison studies. For example, lack of a cold …

Unmet Expectations In Healthcare Settings: Experiences Of Transgender And Gender Diverse Adults In The Central Great Plains, Heather Meyer

Trans Collaborations Academic Papers

Transgender and gender diverse (TGD) individuals face a long-term, multi-faceted process if they choose to begin a gender affirmation journey. Decisions to go on hormone therapy and/or have a surgical procedure necessitate the TGD individual to set up an appointment with a healthcare provider. However, when TGD patients interact with healthcare practitioners, problems can arise. This article documents and categorizes the types of unmet expectations that are common in the TGD patient-healthcare provider social dynamic in the Central Great Plains of the United States. Utilizing a community-based participatory research model, qualitative in-depth interviews were conducted with 27 TGD individuals about …

Using Dna To Identify The Source Of Invasive Mongooses, Herpestes Auropunctatus (Carnivora: Herpestidae) Captured On Kaua‘I, Hawaiian Islands, Darren J. Wostenberg, Matthew W. Hopken, Aaron B. Shiels, Antoinette J. Piaggio

United States Department of Agriculture Wildlife Services: Staff Publications

Two small Indian mongooses (Herpestes auropunctatus) were live-captured in 2012 at separate locations on the Hawaiian Island of Kaua'i, which was previously considered to be free of this invasive species. Genotypes from these two individuals were compared to genotypes of H. auropunctatus from the islands of Hawai'i (n =39), O'ahu (n =91), Maui (n = 39), and Moloka'i (n = 19) to determine the island of origin of the Kaua'i individuals. Genotypes were generated from each individual using five microsatellite loci. Genetic clustering was estimated by Bayesian inference of spatial clustering of individuals and …

Reducing Prairie Dog Populations And Damage By Castration Of Dominant Males, Gary W. Witmer

United States Department of Agriculture Wildlife Services: Staff Publications

Black-tailed prairie dogs (Cynomys ludovicianus) occur widely across the prairie states of North America. They compete with livestock for forage, transmit plague, and damage lawns, landscaping, and property. Interest in non-lethal methods, such as immunocontraception, is growing; however, reductions in the population due to contraception may be offset by increases in survival because adults and yearlings are not subject to the energetic demands of reproduction, and lower densities may increase the amount of resources available to growing offspring. Surgical sterilization provides a means for modeling these effects. Thus, we castrated males prior to the 1998 breeding season to simulate the …

Partners In Crime: Fledgling Tumors Hijack Inflammation, Balamurugan Kuppusamy, Howard A. Young

United States Public Health Resources

While inflammation is a normal physiological response after tissue injury, the chemicals/mediators that are released by the damaged tissue can be toxic to the cells. This underlying inflammation increases the likelihood of cellular DNA damage and aberrant cell growth (Kiraly and others 2015). In this scenario, inflammation functions as a ‘‘behind-curtain factor’’ for many disorders. Cancer has long been known to be closely tethered to inflammation. Widespread evidence shows that inflammatory diseases such as colitis, pancreatitis, and hepatitis make their respective organs highly susceptible to eventual cancer development (Shalapour and Karin 2015). However, other studies have shown that in due …

Advancing Heart, Lung, Blood, And Sleep Research (January 2019)

United States Natonal Institutes of Health: Materials

Advancing Heart, Lung, Blood, and Sleep Research is an 8-page brochure that highlights major NHLBI programs, partnership activities, and other topics.

Urolithin A, A Gut Metabolite, Improves Insulin Sensitivity Through Augmentation Of Mitochondrial Function And Biogenesis, Ashley Mulcahy Toney, Rong Fan, Yibo Xian, Virginia Chaidez, Amanda E. Ramer-Tait, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Objective: Urolithin A (UroA) is a major metabolite of ellagic acid produced following microbial catabolism in the gut. Emerging evidence has suggested that UroA modulates energy metabolism in various cells. However, UroA’s physiological functions related to obesity and insulin resistance remain unclear. Methods: Male mice were intraperitoneally administrated either UroA or dimethyl sulfoxide (vehicle) along with a high-fat diet for 12 weeks. Insulin sensitivity was evaluated via glucose and insulin tolerance tests and acute insulin signaling. The effects of UroA on hepatic triglyceride accumulation, adipocyte size, mitochondrial DNA content, and proinflammatory gene expressions were determined. The impact of UroA on …

Evaluation Of Corn Bran Plus Solubles On Performance And Carcass Characteristics In Finishing Diets, Shelby A. Garland, Bradley M. Boyd, F. Henry Hilscher Hilscher, Galen E. Erickson, Jim C. Macdonald, Ryan A. Mass

Nebraska Beef Cattle Reports

A finishing study was conducted to determine the effect of feeding corn bran plus solubles, a new feed resulting from a pre-fermentation fiber removal process, compared to wet distillers grains plus solubles at two levels of inclusion (20% and 40% of diet DM). Intake increased with inclusion of byproduct, and steers fed 20% wet distillers had the greatest intakes numerically. Byproduct inclusion, regardless of type, increased daily gain over the corn-based control. Feed conversions were improved with increased inclusion of both Bran + Solubles and wet distillers, and both were superior to the control. Increased inclusion of both byproducts resulted …

Effects Of Prepartum Nutrition On May-Calving Cows And Progeny, Alicia C. Lansford, Jacki A. Musgrave, T. L. Meyer Meyer, Rick N. Funston

Nebraska Beef Cattle Reports

May-calving dams grazed either sub-irrigated meadow or upland range from Jan. 5 to May 1 each year for 6 years. Within grazing system, dams received either no supplement or 1 lb/d of a 33% CP supplement from Jan. 5 to April 1. Dams grazing meadow in the prepartum period weighed more and had a greater body condition score prior to calving. They also tended to have greater pregnancy rates in the subsequent breeding season and tended to wean heavier calves than dams grazing upland range. Allowing May-calving dams to graze meadow in late gestation may increase herd profitability through increased …

Impact Of Dietary Fat Source On Beef Tenderness, Felipe A. Ribeiro, Katherine I. Domenech-Perez, Nicolas J. Herrera Herrera, Kellen B. Hart, Chris R. Calkins

Nebraska Beef Cattle Reports

Steers were finished on either a corn control, 40% full-fat modified distillers grains plus solubles, 40% de-oiled modified distillers grains plus solubles, or 38% de-oiled modified distillers grains plus solubles plus 2% corn oil diet to evaluate the effects of dietary fat source on the mechanism of beef tenderization . Feeding modified distillers grains plus solubles increased polyunsaturated fatty acid content in the sarcoplasmic reticulum membrane and increased free Ca²⁺ concentration early postmortem. Steaks from cattle fed de-oiled modified distillers grains and de-oiled modified distillers grains plus corn oil were more tender at 2 d of aging when compared …

Quality Effects On Beef From Cattle Fed High-Protein Corn Distillers Grains And Other Ethanol By-Products, Kellen B. Hart, Felipe A. Ribeiro, Morgan L. Henriott, Nicolas J. Herrera, Chris R. Calkins

Nebraska Beef Cattle Reports

The objective of this study was to evaluate the effects of feeding high protein corn distillers grains on fresh beef quality. Steers were fed one of five diets, either a corn control, high protein distillers grains plus solubles, dry distillers grains plus solubles, wet distillers grains plus solubles, or bran plus solubles diet. Strip loins were aged for 2, 9, or 23 days and placed under retail display conditions for 0 or 7 days. Dietary treatment had no effect on tenderness within each aging period. There were also no differences between treatments for proximate composition, free calcium in the muscle, …

Comparison Of Traditional And Alternative Curing Ingredients On Curing Reactions In A Model Meat System, Faith D. Rasmussen, Gary A. Sullivan

Nebraska Beef Cattle Reports

To meet consumer trends, alternative curing ingredients are used to replace sodium nitrite and cure accelerators. Due to the complexity of meat, it is challenging to compare traditional and alternative ingredients for curing reactions. Using a model system, sources of nitrite (traditional, sodium nitrite and alternative, cultured celery juice powder), salt, and cure accelerators (traditional, sodium erythorbate, or alternative, cherry juice powder) at ingoing sodium nitrite concentrations of 10, 50, 100, 150, or 200 ppm were evaluated for curing reactions. More complete curing reactions were indicated by a higher concentration of cured meat pigment, and lower sulfhydryl groups. Lower residual …

Pooled Analysis Of Individually Fed Finishing Trials, Brett A. Melton, James C. Macdonald, Andrea K. Watson Watson, Galen E. Erickson

Nebraska Beef Cattle Reports

A pooled analysis of 21 finishing trials (2002–2016; 1530 animals) with cattle individually fed in Calan gate barns was conducted. Mixed model regression analysis following random coefficient methodology was used to evaluate relationships between performance variables and carcass characteristics. Gain had a greater effect on efficiency (R² = 0.72) compared to intake (R² = 0.02). The relationship between gain and efficiency was cubic, while intake had a quadratic relationship. The cubic response of gain relative to efficiency was continually increasing with relatively slight curves in the line heavily influenced by points that lay on the ends of the …

Effect Of Adding Urea To Finishing Diets Containing Two Different Inclusions Of Distillers Grains On Steer Performance And Carcass Characteristics, Bradley M. Boyd, James C. Macdonald, Matthew K. Luebbe, Galen E. Erickson

Nebraska Beef Cattle Reports

The effects of adding urea to a dry rolled corn based finishing diet containing low inclusions of distillers grains was evaluated. Treatments were designed as a 2 × 4 factorial arrangement with factors consisting of wet distillers inclusion (either 12 or 20% of diet DM) and urea inclusion (0, 0.4, 0.8, 1.2% of diet DM). There were no significant interactions observed between distillers inclusion and urea inclusion in the diet. Increasing inclusion of distillers grains improved carcass adjusted average daily gain and feed conversion and reduced dry matter intake. Increasing distillers inclusion also increased 12th rib fat and had a …

Evaluation Of Fractionated Distillers Grains (High Protein And Bran Plus Solubles) On Performance And Carcass Characteristics In Finishing Diets, Shelby A. Garland, Bradley M. Boyd, F. Henry Hilscher Hilscher, Galen E. Erickson, Jim C. Macdonald, Ryan A. Mass

Nebraska Beef Cattle Reports

A finishing study evaluated the effect of feeding a new, high protein distillers grains along with corn bran plus condensed distillers solubles compared to traditional wet distillers grains, traditional dry distillers grains and a corn-based control. Each byproduct replaced corn at 40% of the diet dry-matter. Intake was not affected by treatment; however gain and carcass weight were greater and feed conversion improved for high protein distillers and corn bran plus solubles than either type of traditional distillers grains or corn. Based on feed efficiency, the feeding values of high protein distillers grains and corn bran plus solubles are 121% …

Impact Of Shade In Beef Feedyards On Performance, Body Temperature, And Heat Stress Measures, Brett A. Melton, Bradley M. Boyd, Casey Macken Macken, Andrea K. Watson, James C. Macdonald, Galen E. Erickson

Nebraska Beef Cattle Reports

A study using crossbred steers was conducted at a commercial feedyard to determine the effects of pen shades on cattle performance, body temperature, and cattle activity. Two heat events (Event 1 and Event 2) and one cool event were defined for the feeding period. No significant differences were observed for average daily gain, dry matter intake, feed to gain, or carcass characteristics at the end of the trial. During Event 1, cattle in pens with shade had lower panting scores than cattle in open pens. During Event 2, cattle in shade pens had greater dry matter intake, lower panting scores, …

A Comparison Of Synovex One® Alone To Synovex Choice® Followed By Synovex Plus® As Implant Strategies For Finishing Heifers, Elizabeth A. Schumacher, Galen E. Erickson, D. J. Jordon Jordon, Robert J. Cooper, Tony L. Scott, Sheri Bundy, Gary Sides, Ralph M. Cleale

Nebraska Beef Cattle Reports

A commercial feedlot study utilizing 1,737 crossbred heifers (initial BW 690 lb) compared the effect of two implant strategies [Synovex ONE Feedlot (day 0) or Synovex Choice (day 0) followed by Synovex Plus (day 95)] on performance and carcass characteristics. No differences were observed in carcass weight, final body weight, or gain, but heifers implanted with Synovex ONE Feedlot had slightly greater feed conversion and greater intake than heifers implanted using Synovex Choice/Synovex Plus. Heifers implanted with Synovex Choice/Synovex Plus had lower marbling score and yield grade, higher dressing percentage, and greater loin muscle area compared to heifers implanted with …

Effects Of Brown Midrib Corn Silage Hybrids With Or Without Kernel Processing At Harvest On Nutrient Metabolism In Beef Steers, Lauren A. Ovinge, Melissa L. Jolly-Breithaupt, Hannah C. Hamilton Hamilton, John N. Anderson, Galen E. Erickson

Nebraska Beef Cattle Reports

A 2 × 3 factorial digestion study evaluated three corn silage hybrids and kernel processing for finishing steers. The three hybrids included a control corn silage, a brown midrib, and a brown midrib with a softer endosperm. Both brown midrib hybrids had greater fiber digestibility than the traditional control corn silage hybrid. No differences were observed between brown midrib hybrids for all other nutrients. Cattle fed brown midrib hybrids had a lower average ruminal pH compared to the control suggesting more fermentation, but no differences in volatile fatty acid concentration or proportions. Kernel processing had no effect on apparent total …

Effects Of Varying Levels Of Silage Inclusion And Brown Midrib Corn Silage On Finishing Performance Of Steers, Lauren A. Ovinge, F. Henry Hilscher, Brad M. Boyd Boyd, John N. Anderson, Galen E. Erickson

Nebraska Beef Cattle Reports

A 2 × 3 factorial finishing study evaluated traditional or brown midrib corn silage fed at three inclusions in finishing diets. Silage inclusion was 15%, 45%, or 75% inclusion (DM basis) for 70 days followed by 15% inclusion for the remainder of the finishing phase. Cattle were ultrasounded twice to calculate backfat deposition rate for a target backfat of 0.55 inches, as cattle were fed longer if silage inclusion was 45 or 75/15%. Cattle fed 45% or 75/15% silage inclusion had greater final body weight (BW) and days on feed, but higher feed:gain (F:G) than cattle fed 15% silage. Daily …

Impact Of Corn Silage Inclusion On Nutrient Digestion And Rumen Fermentation In Finishing Cattle, Hannah C. Hamilton, Melissa L. Jolly-Breithaupt, Andrea K. Watson Watson, Jim C. Macdonald, Galen E. Erickson

Nebraska Beef Cattle Reports

A digestion study was conducted comparing different inclusions of corn silage used as a roughage source on digestibility, feeding behavior and rumen environment. Treatments consisted of 3 inclusions of corn silage at 0, 7.5 and 15% of the diet DM, and a control treatment with 7.5% alfalfa. As expected, increasing available energy and decreasing roughage (either silage or alfalfa) showed an increase in diet digestibility and ruminal propionate concentrations. However, average ruminal pH was least, with more time spent in subacute acidosis (pH < 5.3) when cattle were fed no roughage. These data suggest that feeding cattle increasing silage inclusions as a roughage source prevented ruminal conditions from entering and remaining in subacute acidosis. Feeding corn silage at 15% gave similar digestibility responses compared to 7.5% alfalfa. Including silage as a roughage source at 15% could help prevent acidosis and digestive upset in feedlot cattle.

Corn Oil Supplementation On Performance And Methane Production In Finishing Steers, Tommy M. Winders, Brad M. Boyd, Henry F. Hilscher, Samodha C. Fernando, Rick R. Stowell, Galen E. Erickson

Nebraska Beef Cattle Reports

A finishing trial was conducted to evaluate the effects of corn oil on animal performance, carcass characteristics, and methane production in finishing cattle. Corn oil was supplemented at 3% of the diet (dry matterbasis) and led to a decrease in intake, a numerical improvement in average daily gain, and improved feed efficiency compared to the control cattle. Dry matter intake while in the methane barn was not decreased between treatments, although it was numerically similar to what was observed outside of the methane barn. Corn oil did not affect any carcass parameters. Methane production (g/d) was reduced with the inclusion …

Biochar Supplementation In Growing And Finishing Diets, Tommy M. Winders, Collin B. Freeman, Brittney A. Mark Mark, Melissa L. Jolly-Breithaupt, Hannah C. Hamilton, Jim C. Macdonald, Galen E. Erickson, Andrea K. Watson

Nebraska Beef Cattle Reports

Two metabolism studies were conducted to evaluate the effects of biochar (0, 0.8, or 3% of diet dry matter) on digestibility and methane production in growing and finishing diets. Intake was not affected by biochar inclusion in the growing diet and increased with 0.8% biochar inclusion in the finishing study. Digestibility tended to increase quadratically with biochar inclusion in the growing study while digestibility tended to linearly decrease with biochar inclusion in the finishing study. Methane production (g/d) decreased 10.7% in the growing study and 9.9% in the finishing study with 0.8% biochar compared to no biochar. Methane production was …

Three Year Summary: Comparison Of Diets Collected From Esophageally Fistulated Cows To Forage Quality Estimated From Fecal Analysis, Bethany M. Johnston, Jay D. Jenkins, Jacki A. Musgrave Musgrave, J. Travis Mulliniks, Mitchell B. Stephenson, James C. Macdonald, L. Aaron Stalker

Nebraska Beef Cattle Reports

Inconsistency was found in forage quality (crude protein and energy) when esophageally fistulated diets were compared to Nutrition Balance Analyzer (NUTBAL) analysis of fecal samples. On upland range sites, hand-clipping of samples (not a recommended practice to measure forage quality), was closer to fistulated diets than NUTBAL analysis. If cattle managers are solely utilizing NUTBAL for estimates of forage value, incorrect supplemental energy and protein decisions will likely be made resulting in the purchase of unnecessary supplements, thereby reducing the profitability of the operation.