Medicine and Health Sciences Commons^™

Ready For Relationships: Promoting Appropriate Dating Behaviors In Adolescents & Young Adults With Intellectual & Developmental Disabilities, Lauren Buch, Ots, Kelly Dennin, Ots, Chelsea Fife, Ots, Eileen Mee, Ots, E. Adel Herge

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Objectives:

• Identify the need for effective relationship, sexuality expression, and sex education programming for adolescents with IDD based on current literature.
• Examine the role of occupational therapy in facilitating the development of healthy dating behaviors for adolescents with IDD.
• Apply components of a best practice approach to facilitate the development of appropriate dating behaviors for adolescents with IDD.

PICO Question:

What interventions within the scope of occupational therapy will lead to appropriate dating behaviors in adolescents and young adults with intellectual and developmental disabilities?

Smooth Transitions: Adapting To New Roles For Transgender Individuals, Rylea Hager, Ots, Daniella Mazzo, Ots, Meredith O’Neal, Ots, Eileen Young, Ots, Rebecca Sinko, Otd, Otr/L

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Outcomes:

• Define transgender and understand the occupational challenges associated with the gender-affirming transition process.
• Discuss the impact of the knowledge gap in gender-inclusive care, as well as the barriers to accessing healthcare services for transgender individuals.
• Acquire knowledge from current research and apply to occupational therapy interventions for transitioning transgender individuals in the process of new role assumption

PICO Question:

How can occupational therapists utilize interventions within their scope of practice (I) to promote positive transitions to new occupational roles (O) for individuals who are transgender (P)?

Let’S Get Spiritual! How Integrating Spirituality Into The Ot Process Impacts Well-Being For Those Experiencing A Life-Altering Diagnosis, Taneisha Esplin Jolley, Ots, Jeffrey Gold, Ms, Ots, Nicholas Luca, Ots, Antôn Nguyễn, Ots, E. Adel Herge, Otd, Otr/L, Faota

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Outcomes:

• Define spirituality as it applies to the scope of occupational therapy practice for individuals experiencing life-altering diagnoses and conditions
• Describe current evidence that supports incorporating clients’ spirituality into the occupational therapy process to ensure a holistic approach to practice
• Apply spiritual-based interventions in order to achieve positive outcomes for individuals experiencing life-altering diagnoses and conditions

PICO Question:

How does incorporating spirituality within the OT process impact well-being/QOL for individuals who have experienced life-altering conditions or diagnoses?

Moving On Up: The Transition From Middle To High School For Neurotypical Adolescents, Corinne Dever, Ots, Julia Forebaugh, Ots, Alexandra Mangino, Ots, Madeline Gamble, Ots, Samantha Morse, Ots, Rebecca Sinko, Otd, Otr/L

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Objectives

• Define the role of occupational therapy for the middle to high school transition.
• Identify potential interventions within the scope of occupational therapy to facilitate the transition from middle to high school.
• Acquire the knowledge from current research to apply occupational therapy interventions to neurotypical adolescents transitioning from middle to high school.

PICO Question

What kind of (I) interventions fall within the scope of occupational therapy (O) to increase school participation for (P) neurotypical adolescents transitioning from middle school to high school?

A Grief All Its Own, Mary Blumenfeld

Student Papers, Posters & Projects

No abstract provided.

Safety And Efficacy Of Hydroxychloroquine In Covid-19: A Systematic Review And Meta-Analysis, Waqas Ullah, Hafez M. Abdullah, Sohaib Roomi, Yasar Sattar, Talal Almas, Smitha Narayana Gowda, Rehan Saeed, Maryam Mukhtar, Ammar Ahmad, Tony Oliver, M. Chadi Alraies, Donald C. Haas, David L. Fischman

Abington Jefferson Health Papers

Background: During the initial phases of the coronavirus disease 2019 (COVID-19) epidemic, there was an unfounded fervor surrounding the use of hydroxychloroquine (HCQ); however, recently, the Centers for Disease Control and Prevention (CDC) has recommended against routine use of HCQ outside of study protocols citing possible adverse outcomes.

Methods: Multiple databases were searched to identify articles on COVID-19. An unadjusted odds ratio (OR) was used to calculate the safety and efficacy of HCQ on a random effect model.

Results: Twelve studies comprising 3,912 patients (HCQ 2,512 and control 1400) were included. The odds of all-cause mortality (OR: 2.23, 95% confidence …

Comparative Accuracy Of Non-Invasive Imaging Versus Right Heart Catheterization For The Diagnosis Of Pulmonary Hypertension: A Systematic Review And Meta-Analysis., Waqas Ullah, Artem Minalyan, Sameer Saleem, Nayab Nadeem, Hafez M Abdullah, Abdelmohaymin Abdalla, Vincent Chan, Rehan Saeed, Maria Khan, Sara Collins, Maryam Mukhtar, Harshwant Grover, Yasar Sattar, Ankur Panchal, Smitha Narayana Gowda, Uneza Khwaja, Bilal Lashari, David L Fischman

Abington Jefferson Health Papers

Background: Right heart catheterization (RHC) is the gold-standard in the diagnosis of pulmonary hypertension (PH) but at the cost of procedure-related complications. We sought to determine the comparative accuracy of RHC versus non-invasive imaging techniques such as computed tomography (CT), magnetic resonance imaging (MRI), and transthoracic echocardiography (TTE).

Methods: Pulmonary hypertension was defined as a mean pulmonary artery pressure (mPAP) of>20 mmHg. Multiple databases were queried for relevant articles. Raw data were pooled using a bivariate model to calculate the measures of diagnostic accuracy and to estimate Hierarchical Summary Receiver Operating Characteristic (HSROC) on Stata 13.

Results: A total …

Ureteroscopic Biopsy Of Upper Tract Urothelial Carcinoma And Role Of Urinary Biomarkers, Katherine E Smentkowski, Demetrius H. Bagley, Scott G. Hubosky

Department of Urology Faculty Papers

Ureteroscopic biopsy is an integral part of diagnosis of urothelial carcinoma of the upper urinary tract. It can be a technical challenge, but diagnostic rates have improved remarkably with refinements in surgical technique and specimen processing. Cytology aids with diagnosis and other urinary biomarkers continue to evolve, which may help further stratify patients for treatment. The current literature on the ureteroscopic biopsy and role of urinary biomarkers is reviewed and summarized below.

Chimeric Ad5.F35 Vector Evades Anti-Adenovirus Serotype 5 Neutralization Opposing Gucy2c-Targeted Antitumor Immunity, John C. Flickinger, Jagmohan Singh, Robert D Carlson, Elinor Leong, Trevor R. Baybutt, Joshua Barton, Ellen M. Caparosa, Amanda M. Pattison, Jeff A. Rappaport, Jamin Roh, Tingting Zhan, Babar Bashir, Scott A Waldman, Adam E. Snook

Department of Pharmacology and Experimental Therapeutics Faculty Papers

BACKGROUND: Adenovirus serotype 5 (Ad5) is a commonly used viral vector for transient delivery of transgenes, primarily for vaccination against pathogen and tumor antigens. However, endemic infections with Ad5 produce virus-specific neutralizing antibodies (NAbs) that limit transgene delivery and constrain target-directed immunity following exposure to Ad5-based vaccines. Indeed, clinical trials have revealed the limitations that virus-specific NAbs impose on the efficacy of Ad5-based vaccines. In that context, the emerging focus on immunological approaches targeting cancer self-antigens or neoepitopes underscores the unmet therapeutic need for more efficacious vaccine vectors.

METHODS: Here, we evaluated the ability of a chimeric adenoviral vector (Ad5.F35) …

Characterization Of Initial North American Pediatric Surgical Response To The Covid-19 Pandemic, Martha-Conley E Ingram, Mehul V Raval, Christopher Newton, Monica E Lopez, Loren Berman, Md

Department of Surgery Faculty Papers

INTRODUCTION: The impact of COVID-19 pandemic on pediatric surgical care systems is unknown. We present an initial evaluation of self-reported pediatric surgical policy changes from hospitals across North America.

METHODS: On March 30, 2020, an online open access, data gathering spreadsheet was made available to pediatric surgeons through the American Pediatric Surgical Association (APSA) website, which captured information surrounding COVID-19 related policy changes. Responses from the first month of the pandemic were collected. Open-ended responses were evaluated and categorized into themes and descriptive statistics were performed to identify areas of consensus.

RESULTS: Responses from 38 hospitals were evaluated. Policy changes …

The Implications Of Paraspinal Muscle Atrophy In Low Back Pain, Thoracolumbar Pathology, And Clinical Outcomes After Spine Surgery: A Review Of The Literature., Kevin He, Jeffery Head, Nikolaos Mouchtouris, Kevin Hines, Phelan Shea, Richard Schmidt, Christian Hoelscher, Geoffrey Stricsek, James Harrop, Ashwini Sharan

Department of Neurosurgery Faculty Papers

STUDY DESIGN: Literature review.

OBJECTIVES: Paraspinal muscle integrity is believed to play a critical role in low back pain (LBP) and numerous spinal deformity diseases and other pain pathologies. The influence of paraspinal muscle atrophy (PMA) on the clinical and radiographic success of spinal surgery has not been established. We aim to survey the literature in order to evaluate the impact of paraspinal muscle atrophy on low back pain, spine pathologies, and postoperative outcomes of spinal surgery.

METHODS: A review of the literature was conducted using a total of 267 articles identified from a search of the PubMed database and …

Lc-Ms Based Stability-Indicating Method For Studying The Degradation Of Lonidamine Under Physical And Chemical Stress Conditions, Ankit K. Rochani, Margaret A. Wheatley, Brian Oeffinger, John R. Eisenbrey, Gagan Kaushal

College of Pharmacy Faculty Papers

Background and purpose: Lonidamine is a hexokinase II inhibitor, works as an anticancer molecule, and is extensively explored in clinical trials. Limited information prevails about the stability-indicating methods which could determine the forced degradation of lonidamine under stressed conditions. Hence, we report the use of a rapid, sensitive, reproducible, and highly accurate liquid chromatography and mass spectrometry method to analyze lonidamine degradation. Experimental approach: The Xbridge BEH shield reverse phase C18 column (2.5 μm, 4.6 × 75 mm) using isocratic 50:50 water: acetonitrile with 0.1% formic acid can detect lonidamine with help of mass spectrometer in tandem with an ultraviolet …

Perioperative Anticoagulation Management In Spine Surgery: Initial Findings From The Ao Spine Anticoagulation Global Survey., Philip Louie, Garrett Harada, James Harrop, Thomas Mroz, Khalid Al-Saleh, Giovanni Barbanti Brodano, Jens Chapman, Michael Fehlings, Serena Hu, Yoshiharu Kawaguchi, Michael Mayer, Venugopal Menon, Jong-Beom Park, Sheeraz Qureshi, Shanmuganathan Rajasekaran, Marcelo Valacco, Luiz Vialle, Jeffrey C Wang, Karsten Wiechert, K Daniel Riew, Dino Samartzis

Department of Neurosurgery Faculty Papers

STUDY DESIGN: Cross-sectional, international survey.

OBJECTIVES: This study addressed the global perspectives concerning perioperative use of pharmacologic thromboprophylaxis during spine surgery along with its risks and benefits.

METHODS: A questionnaire was designed and implemented by expert members in the AO Spine community. The survey was distributed to AO Spine's spine surgeon members (N = 3805). Data included surgeon demographic information, type and region of practice, anticoagulation principles, different patient scenarios, and comorbidities.

Results: A total of 316 (8.3% response rate) spine surgeons completed the survey, representing 64 different countries. Completed surveys were primarily from Europe (31.7%), South/Latin America (19.9%), and …

Dermatology Journals And The Impact Factor, Lawrence Charles Parish, W Clark Lambert

Department of Dermatology and Cutaneous Biology Faculty Papers

The noted informatics authority, Eugene Garfield (1925-2017), while working at the Johns Hopkins Medical Library, decided to assist medical librarians in selecting the publications to which they should subscribe. Not only at issue was the expense of subscribing and binding the periodicals, but there was also the physical space for shelving them. This was the birth of the Science Citation Index (SCI), the Impact Factor (IF), and the Institute for Scientific Information (ISI)in Philidelphia.

The role of the SCI has expanded over the years. Libraries may still continue to select journals on the basis of their IF, with many institutions …

You Don’T Have To Get Diabetes, Mitch Kaminski, Md, Mba, Nevaneva White, Dnp, Crnp, Cdces

Department of Family & Community Medicine Presentations and Grand Rounds

The goal is to streamline the steps required to make referrals to and enroll in the National Diabeties Prevention Program (DPP).

Cancer Prevention And Therapeutics For The Primary Care Clinician, Richard C. Wender, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Outline

•Basics of cancer screening •Recommended options for colorectal cancer screening •Trends in incidence and mortality •The 80% in Every Community initiative

2020 James B. Erdmann, Phd Award Recipients

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Jefferson Center for Interprofessional Practice and Education (JCIPE) congratulates this year's award winners and thanks them for all their efforts to support and advance this work on campus and beyond.

Health Mentors Reflection, Julie Distasi

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

My experience with the Health Mentors Program has been truly enjoyable.

Reflection: Enhancing Research And Training Through Interprofessional Collaboration And Mentorship, Kayla Askey, Pharmd Candidate 2020

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Throughout pharmacy school, I had the opportunity to take part in a variety of different interprofessional education events. Although all were valuable and worthwile, it wasn't untill I began collaborating with other professional disiciplines through research that I witnessed the real power of interprofesssional collaboration.

The Old Pine Community Center In Philadelphia Responds To Covid-19, April T. Jones, Med

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

I have always believed in the power of community. It is why I was compelled to serve as the CEO and Executive Director of the Old Pine Community Center and why I continue to stand at the helm.

Meet An Ipe Student Champion From Thomas Jefferson University

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Nick Safian, Sidney Kimmel Medical College, M2

1. Briefly describe your work with/related to JCIPE.
2. What excites you about this work?
3. What have you learned that was new?
4. Why is IPE/CP important to you?
5. How do you think you will apply your IPE/CP training to your future role

Prescribing For Pain: What Medical Students Learn And Where They Learn It, Chidinma Tiko-Okoye, Md Mph, Brian Mcanany, Mph, Sharon Larson, Phd:

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

• State of Issue/Problem Addressed
• Background
• Methodology
• Results
• Discussion
• Conclusion

Meet An Ipe Faculty Champion From Thomas Jefferson University

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Leigh Ann Hewston

1. Briefly describe your work with/related to JCIPE.
2. What excites you about this work?
3. Why is IPE/CP important to you?

Implementation Of Family Psychosocial Risk Assessment In Pediatric Cancer With The Psychosocial Assessment Tool (Pat): Study Protocol For A Cluster-Randomized Comparative Effectiveness Trial, Anne E Kazak, Janet A Deatrick, Michele A Scialla, Eric Sandler, Rebecca E Madden, Lamia P Barakat

Department of Pediatrics Faculty Papers

BACKGROUND: Childhood cancer affects and is affected by multiple levels of the social ecology, including social and relational determinants of health (e.g., economic stability, housing, childcare, healthcare access, child and family problems). The 2015 Standards of Psychosocial Care in Pediatric Cancer outline optimal psychosocial care sensitive to these ecological factors, starting with assessment of psychosocial healthcare needs to promote medical and psychosocial outcomes across all children with cancer. To address the first standard of family psychosocial assessment, the Psychosocial Assessment Tool (PAT) is a validated screener ready for broad implementation.

METHOD: The PAT will be implemented across a national sample …

Esrd And Endoavf: A Giant Leap Forward, Alison Tan, Md

Department of Family & Community Medicine Presentations and Grand Rounds

No abstract provided.

Interprofessional Continuous Professional Development In Qatar, Sara F. Mahoud, Pharmd, Bccp

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Hamad Medical Corporation (HMC) is the main governmental healthcare entity overseeing twelve hospitals which serve different specialties and geographical areas across the state of Qatar. At HMC, the pharmacy executive office oversees its Continuous Pharmacy Profeesional Development (CPPD) office. Since 2016, the CPPD office accomplished a lot of great achievements. Here is waht we learned so far about interprofessional education.

Jefferson Covid Stories, Danielle Snyderman, Md, Cmd, Nick Safian

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

The concept of Jefferson COVID stories was modeled after the Humans of New York photojournalism project. I approached Nick Safian, Sidney Kimmel Medical College, MS2, and together we started to create writing prompts to engage teh entire Jefferson community on a weekly basis.

From The Editors

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

As we write this Letter from the Editors, we are acutely aware that we are in a very different place than ever before. We know that this semester has been exceptionally challenging with the rapid transition to working, teaching and providing critical care in different formats and adapted settings to do our part to prevent the spread of a global pandemic, unprecidented in our lifetimes.

Collaborative Healthcare: Interprofessional Practice, Education And Evaluation (Jcipe), Volume 11, Number 1, Spring 2020/Summer 2020

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

In this Issue

1- From the Editors

3- Jefferson Covid Stories

4- Interprofessional Continuous Professional Development in Qatar

5- Meet and IPE Faculty Champion from Thomas Jefferson University

6- Prescribing for Pain: What Medical Students Learn and Where They Learn It

7- Meet an IPE Student Champion from Thomas Jefferson University

8- The Old Pine Community Center in Philadelphia Responds to COVID-19

9- Reflection: Enchancing Research and Training Through Interprofessional Collaboration and Mentorship

10- Health Mentors Reflection

10- 2020 James B. Erdmann, PhD Award Recipients

Computational Identification Of Gene Networks As A Biomarker Of Neuroblastoma Risk, Lidan Sun, Libo Jiang, Christa N Grant, Hong-Gang Wang, Claudia Gragnoli, Zhenqiu Liu, Rongling Wu

Division of Endocrinology, Diabetes and Metabolic Diseases Faculty Papers

Neuroblastoma is a common cancer in children, affected by a number of genes that interact with each other through intricate but coordinated networks. Traditional approaches can only reconstruct a single regulatory network that is topologically not informative enough to explain the complexity of neuroblastoma risk. We implemented and modified an advanced model for recovering informative, omnidirectional, dynamic, and personalized networks (idopNetworks) from static gene expression data for neuroblastoma risk. We analyzed 3439 immune genes of neuroblastoma for 217 high-risk patients and 30 low-risk patients by which to reconstruct large patient-specific idopNetworks. By converting these networks into risk-specific representations, we found …