Medicine and Health Sciences Commons^™

We Can Do It Together: Par1/Par2 Heterodimer Signaling In Vsmcs., Rafal Pawlinski, Michael Holinstat

Department of Medicine Faculty Papers

In this issue, Sevigny and colleagues demonstrate that a protease-activated receptor 1 (PAR1)-PAR2 heterodimer regulates vascular smooth muscle cell (VSMC) hyperplasia following vascular injury ¹. PARs belong to a family of G-protein coupled receptors that are proteolytically activated by a variety of proteases ^{2, 3}. Cleavage of PARs results in intracellular signaling mediated by activation of various G proteins including G_12/13, G_q, and G_i ^{2, 4-6}. The PAR family consists of 4 members, PAR1-PAR4, with PARs 1, 3, and 4 being primarily activated by thrombin, while PAR2 is activated by trypsin and …

Promoting Your Institutional Repository On And Off Campus, Daniel G. Kipnis, Msi

Academic Commons and Scott Memorial Library Staff Papers and Presentations

Webinar presentation for Association for Library Collections and Technical Services.

Navigating The Digital Divide: A Teaching-Learning Initiative With The Ipad2, Beth Ann Swan, Kathryn Shaffer, Kellie Smith, Anthony J. Frisby, Mary Hanson-Zalot

College of Nursing Faculty Papers & Presentations

Background/ Rationale: It has been established that Interprofessional Education (IPE) offers a solution to foster teamwork and improve patient care and should be implemented early in professional role development. Thomas Jefferson University has been providing IPE to interprofessional healthcare students for over 5 years. A long term strategic goal was identified to “create innovative learning environments that support interprofessional education including state-of-the-art technologies”. In actualizing this goal, the curriculum was enhanced with technology supported collaborative learning techniques to assist in group processing and reflection. Combining traditional IPE activities with technology supported components incorporated the advantages of both delivery methods, …

Molecular Diagnostics In Periprosthetic Joint Infection., Javad Parvizi, Lesley Walinchus, Bahar Adeli

Department of Orthopaedic Surgery Faculty Papers

Periprosthetic joint infection (PJI) is a significant and costly challenge to the orthopedic community. The lack of a gold standard for diagnosis remains the biggest obstacle in the detection and subsequent treatment of PJI. Molecular markers in the serum and joint fluid aspirate hold immense promise to enhance the development of a firm diagnostic criterion. The primary goal is one marker with high sensitivity and specificity. Here, we review our current research efforts in the field of molecular markers: C-reactive protein, erythrocyte sedimentation rate, white blood cells, and leukocyte esterase. Each marker has been studied to determine its sensitivity, specificity, …

Food Matters: Clinical Education And Advocacy Training

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Jsph Announces The Center For Value In Healthcare

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Personalized Medicine: Transforming The Future Of Healthcare - Health Policy Forum- June 9, 2011

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Joseph S. Gonnella, Md Scholarship Awarded To Jonathan Musyt

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Improving Health Literacy In The Cardiovascular Population: A Regional Approach In Southeastern Pennsylvania, Patricia Yurchick Rn,Mba,Cphq

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Jsph Faculty Profile - Spotlight On Diane J. Abatemarco, Phd, Msw

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Jsph Summer Seminar - The Next Phase

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

A Teacher's Perspective On Online Graduate Education, Harm J. Scherpbier Md

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

President Robert L. Barchi, Md, Phd, Tju 2011 Commencement Speech

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Medical-Legal Partnerships As A Value-Add To Patient-Centered Medical Homes, Martha Romney Rn,Ms,Jd,Mph

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Health Policy Newsletter Fall 2011 Download Full Pdf

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

About The Authors

Jefferson Journal of Psychiatry

About the Authors, Jefferson Journal of Psychiatry, Volume 11, Number 1, 1993.

The Abc's Of Schizophrenia, Mary Donovan, Md

Jefferson Journal of Psychiatry

SCHIZOPHRENIA GENESIS, THE ORIGINS OF MADNESS

Irving I. Gottesman

W.H. Freeman and Company, New York, 1991

296 pages, $14.95, paperback

A New Voice On Personality Disorders, Dan Block, M.D.

Jefferson Journal of Psychiatry

BROKEN STRUCTURES: SEVERE PERSONALITY DISORDERS AND THEIR TREATMENT

Salman Akhtar, M.D.

Jason Aronson, Inc., 1991

So Much Success, So Little Joy, Robert Neil Gerstman, D.O.

Jefferson Journal of Psychiatry

GOOD GRIEF: THE STORY OF CHARLES M. SCHULTZ

Rheta Grimsley Johnson

Pharos Books, New York 1989

$17.95, 256 pgs.

Perspectives On Psychotherapy: In Our Evolving Profession, Susan M. Hall, M.D.

Jefferson Journal of Psychiatry

MOMENTS OF ENGAGEMENT: INTIMATE PSYCHOTHERAPY IN A TECHNOLOGICAL AGE

Peter D. Kramer , M.D.

W.W. Norton & Co.1989

Hardcover, 260 pp., $24.95

Letters To The Editor

Jefferson Journal of Psychiatry

Letters to the Editor. Jefferson Journal of Psychiatry, Volume 11, Number 1, 1993.

A Resident Initiated Prite Review Course: Trials And Tribulations, David W. Metzler, M.S., M.D., Daniel L. Kinsey, M.D., Lesley R. Dickson, M.D., Mark Hyatt, M.D.

Jefferson Journal of Psychiatry

The experience of developing a review course to study for the Psychiatry Resident's In-Training Exam (PRITE) is discussed. Residents in our program felt that the review course was useful with respect to the following: studying for the PRITE; future study for National Boards; and learning of new material.

The Psychiatry Resident's In-Training Exam (PRITE) was developed in 1979 as a mechanism to assess the knowledge base of psychiatric residents in a standardized format (1,2,3). The exam was originally designed to simulate the American Board of Psychiatry and Neurology (ABPN) examination, PART I, and has gained widespread acceptance despite questions about …

Thalamic Tumor Presenting As Major Depression And Headache, Robert Jay Claire, M.D.

Jefferson Journal of Psychiatry

We report the case of a 39 year old male who presented with Major Depression, headache, and apathy. Within six weeks of his initial presentation the patient died from a "Central Herniation Syndrome" after biopsy of a left thalamic lesion. The statistics of medical problems presenting as psychiatric disorders as well as recent literature on personality changes associated with thalamic infiltration are reviewed.

It is recognized that from 33-80% of inpatient psychiatric patients have concurrent medical disease. A large proportion of these are unrecognized prior to psychiatric hospitalization (1). In 1983, Martin clearly stated that "psychiatric symptoms are often the …

Five Hours With Frank: A Case Study, Mark E. Kunik, M.D.

Jefferson Journal of Psychiatry

This manuscript explores a resident's dilemma when performing a psychiatric evaluation within the context of releasing a convicted rapist.

A Case Report Of Folie'a Deux: Husband-And-Wife, Ryan M. Nishihara, Craig T. Nakamura

Jefferson Journal of Psychiatry

Shared paranoid disorder is a relatively rare psychiatric disorder in which paranoid delusions are transferred from one individual to one or more other susceptible person(s) in close association. Folie a deux describes a shared paranoid disorder involving two people and is characterized by a complex dependant relationship between the involved individuals. Provided there is no additional underlying psychopathology, there is a good prognosis for the submissive partner. Here we present a case report and discussion off folie a deux involving a husband and wife. Although folie a deux is a relatively uncommon disorder, it is important to recognize such cases …

Clozapine-Induced Seizures And Eeg Changes: A Case Report And Discussion Of Clinical Management, Jeffrey Daly, M.D., Stephen Salloway, M.D., M.S.

Jefferson Journal of Psychiatry

Clorapine is an atypical antipsychotic agent associated with a higher frequency of seizures than standard neuroleptics. In addition, clozapine causes epileptiform abnormalities in the EEG in up to 72% of patients. A patient who developed a generalized seizure shortly after beginning clozapine treatment and the patient's EEG findings are presented. The neuropharmacology of dozapine and the management of clozapine-induced seizures and EEG abnormalities are discussed.

Cultural Aspects Of A Patient's Symptomatology: A Case Report, Theresa M. Miskimen, M.D.

Jefferson Journal of Psychiatry

Culture influences numerous aspects of human experience including behavior, beliefs, values and attitudes. A case report is presented emphasizing how cultural manifestations of a psychiatric illness may materially affect presentation of symptoms, illness perception, and explanatory model of illness of a patient. Cultural background is explored to offer improved rapport and patient care.

Entering Academic Psychiatry: A Resident's Perspective, Julio Licinio, M.D.

Jefferson Journal of Psychiatry

University-based psychiatry residency programs encourage the pursuit of academic careers, both on admission, by favoring applicants with evidence of a commitment to investigation, and after residency training, by selecting as faculty residents who have demonstrated academic and research productivity. While attempting to achieve multiple goals, some residents may be discouraged to pursue an academic career as a result of marked conflict between the clinical and academic components of training. The substantial differences in priorities among psychiatry residents ought to be explored early in residency training by devoting seminars to career planning and by facilitating the pursuit of academic activities under …

The Other Drug War: Societal Attitudes And The Pharmacologic Treatment Of Anxiety Disorders, Bruce Wenokur, D.O., M.P.H.

Jefferson Journal of Psychiatry

Societal attitudes with respect to mood altering agents have undergone cyclical changes through American history. Cycles of relative tolerance and intolerance affect the perception of psychotropic drugs for illicit use, as well as legitimate medical therapy, often creating confusion between these two realms. This article examines the relationship between the prevailing social climate and the subsequent restrictions placed on the use of opiates. Historical attitudes toward opiate use serve as a model to explore the current social climate as it pertains to the pharmacologic treatment of anxiety. The under treatment of anxiety disorders is hypothesized to result largely from social …

A Comparative Content Analysis Of Emily Dickinson's Letters, Patricia Harrison, M.D., Carol Mcleod, M.A.

Jefferson Journal of Psychiatry

To investigate the relationship between creativity and mental illness, a computer content analysis of a random sampling of Emily Dickinson's (ED) letters and a selected sample of ED's "anxiety" letters were compared with speech samples from female subjects with panic disorder (n = 4) and speech samples from a female control group (n = 8). Although this can only be considered a pilot study, the findings suggest that ED's word profiles are more similar to the panic disorder group than to the control group. Limitations of this study (i.e., small sample sizes) and suggestions for future research are discussed.