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Articles 5011 - 5040 of 8080
Full-Text Articles in Medicine and Health Sciences
Effects Of Adenosine A1 Receptor Agonist Ccpa And Antagonist Dpcpx On Ischemia/Reperfusion-Induced Arrhythmias In Rats*, Ömer Bozdoğan, Ersöz Gonca, Nuran Ekerbi̇çer
Effects Of Adenosine A1 Receptor Agonist Ccpa And Antagonist Dpcpx On Ischemia/Reperfusion-Induced Arrhythmias In Rats*, Ömer Bozdoğan, Ersöz Gonca, Nuran Ekerbi̇çer
Turkish Journal of Medical Sciences
Adenosine has been commonly used to treat supraventricular tachycardia in clinics. However, there are only a few studies on the effects of adenosine on ischemia or reperfusion induced arrhythmia and they conflict with the results of the present study. During this study, we aimed to clarify the effect of adenosine on ischemia-reperfusion induced arrhythmia. Materials and methods: Left coronary artery was ligated for 6 min and it was released for 15 min to produce reperfusion. A1 adenosine agonist CCPA (2 Chloro - N6 - Cyclopentyl-adenosine), and A1 selective antagonist DPCPX (8 - Cyclopentyl - 1,3 -dipropylxanthine) in 5 µg/kg dose …
Morphine Modulates Microvascular Leakage Dose-Dependently In The Airway Of Ovalbumin-Sensitized Rats, Seyfullah Oktay Arslan
Morphine Modulates Microvascular Leakage Dose-Dependently In The Airway Of Ovalbumin-Sensitized Rats, Seyfullah Oktay Arslan
Turkish Journal of Medical Sciences
To investigate the effect of morphine on ovalbumin-evoked airway microvascular leakage in sensitized rats. Materials and methods: Rats were sensitized on days 0, 14, and 21 with ovalbumin. Intravenous ovalbumin (2 mg/kg) or capsaicin (50 µg/kg) increased the extravasation of Evans blue dye in trachea, bronchi, and intra-pulmonary tissues of sensitized rats. Results: Morphine (1-10 mg/kg) inhibited ovalbumin-evoked increase in microvascular plasma leakage in a dose-dependent manner; however, it had no significant effect at the doses of 0.1 or 30 mg/kg. In addition, morphine, at the doses of 1-30 mg/kg, abolished microvascular leakage increased by capsaicin. The inhibition caused by …
The Effect Of L-Tryptophan On The Heart In Rabbits Via Chronic Hypoxia, Fi̇gen Nari̇n, Nazmi̇ Nari̇n, Fatmagül Başarslan, Ali̇ Baykan, Sadetti̇n Sezer, Hülya Akgün, Aynur Akin, Mustafa Akçakuş, Hakan Ceyran
The Effect Of L-Tryptophan On The Heart In Rabbits Via Chronic Hypoxia, Fi̇gen Nari̇n, Nazmi̇ Nari̇n, Fatmagül Başarslan, Ali̇ Baykan, Sadetti̇n Sezer, Hülya Akgün, Aynur Akin, Mustafa Akçakuş, Hakan Ceyran
Turkish Journal of Medical Sciences
To evaluate the protective effect of tryptophan on an experimentally produced hypoxic myocardial injury via biochemical and pathological parameters. Materials and methods: A total of 26 rabbits were divided into 3 groups. Group 1 (n = 9) was only exposed to hypoxia. Group 2 (n = 10) was exposed to hypoxia and received L-tryptophan (200 mg/kg per day, orally for 5 days). Group 3 (n = 7) was the control group. Before the hypoxic injury and after the delivery of the medication, serum samples were taken for troponin-I, creatine kinase myocardial isoenzymes (CK-MB), lactate dehydrogenase (LDH), glutathione peroxidase (GSH-Px), superoxide …
Marital Adjustment And Emotional Symptoms In Infertile Couples: Gender Differences, Verda Tüzer, Altuğ Tuncel, Sema Göka, Süheyla Doğan Bulut, Fati̇h Volkan Yüksel, Ali̇ Atan, Erol Göka
Marital Adjustment And Emotional Symptoms In Infertile Couples: Gender Differences, Verda Tüzer, Altuğ Tuncel, Sema Göka, Süheyla Doğan Bulut, Fati̇h Volkan Yüksel, Ali̇ Atan, Erol Göka
Turkish Journal of Medical Sciences
To determine the psychosocial and demographic factors related to marital adjustment and emotional symptoms in infertile couples according to gender differences. Materials and methods: The study sample, consisting of 60 primary infertile couples, was assessed using the Beck Depression Inventory, State and Trait Anxiety Inventory, and Dyadic Adjustment Scale. The scores derived from men and women were compared according to infertility factor. Multiple regression analysis models were used to explore the linkages between emotional symptoms and marital adjustment. Results: Statistically significant gender differences were noted in affectional expression and sexual satisfaction domains of the Dyadic Adjustment Scale (P < 0.05). Our analyses showed that various aspects of marital adjustment have predictive power on anxiety and depressive symptoms of infertile men, especially when the infertility is due to male factor. Conclusion: Results of this study emphasize the importance of psychological and sexual counseling in the course of infertility treatment.
Implications Of Socio-Economic Status On The Dietary Fatty Acid Intakes In Turkish Women, Zehra Büyüktuncer, Berat Nursal Tosun, Ayli̇n Ayaz, Makbule Gezmen Karadağ, Alev Kocabaş Keser, Meral Aksoy, Mi̇ne Yurttagül, Sevi̇nç Yücecan, Hali̇t Tanju Besler
Implications Of Socio-Economic Status On The Dietary Fatty Acid Intakes In Turkish Women, Zehra Büyüktuncer, Berat Nursal Tosun, Ayli̇n Ayaz, Makbule Gezmen Karadağ, Alev Kocabaş Keser, Meral Aksoy, Mi̇ne Yurttagül, Sevi̇nç Yücecan, Hali̇t Tanju Besler
Turkish Journal of Medical Sciences
To investigate the effects of socio-economic status (SES) on the dietary intakes of fatty acids in a group of Turkish women. Materials and methods: Five hundred and sixty three women were randomly enrolled into the study. They were classified into 3 SES groups: group 1 high (n = 186), group 2 medium (n = 186), and group 3 low (n = 191). The groups were determined by the SES distribution of Ankara as determined by the 2000 census. Each participant was investigated with a questionnaire consisting of demographic characteristics, physical activity level (24-h record), and dietary intake (24-h recall) by …
Exposure To Continuous Darkness Leads To Atypical Symptoms Of Seasonal Affective Disorder In Rats, Çağla Ayhan İşman, Nesli̇han Toyran, Ni̇met Ünay Gündoğan
Exposure To Continuous Darkness Leads To Atypical Symptoms Of Seasonal Affective Disorder In Rats, Çağla Ayhan İşman, Nesli̇han Toyran, Ni̇met Ünay Gündoğan
Turkish Journal of Medical Sciences
Prolonged duration of nocturnal melatonin increase has been implicated in the pathogenesis of the seasonal affective disorder (SAD) winter depression. This study was designed to investigate behavioral and physiological consequences of constant dark exposure in male rats for its potential application to human affective disorders. Materials and methods: A total of 12 male Wistar-Albino rats (230-290 g) were assigned to control (LD 12:12 h; n = 6) and constant darkness (DD, 10 days; n = 6) groups. Experimental protocol included comparison of behavioral (FST, open field test, and sucrose preference) and physiological (body weight, food intake, and blood glucose level) …
Anti-Diabetic Activity Of Tinospora Cordifolia (Willd.) In Streptozotocin Diabetic Rats; Does It Act Like Sulfonylureas?, Nagaraja Puranik, Kararashah Fakruddin Kammar, Sheela Devi
Anti-Diabetic Activity Of Tinospora Cordifolia (Willd.) In Streptozotocin Diabetic Rats; Does It Act Like Sulfonylureas?, Nagaraja Puranik, Kararashah Fakruddin Kammar, Sheela Devi
Turkish Journal of Medical Sciences
As an alternative medicine to treat diabetes mellitus, many herbal drugs are being studied throughout the world. In the present study, an attempt was made to investigate the anti-diabetic activity of Tinospora cordifolia (Willd.) (TC) stem extracts (both aqueous and alcoholic) in different dosages (200 and 400 mg/kg b.w.) in streptozotocin diabetic albino rats. The probable mechanism by which TC may act as an anti-hyperglycemic drug was also investigated. Materials and methods: The drug was administered orally for 10 days and 30 days in different groups of animal, with each group containing 6 animals. The efficacy of this drug was …
Isolation Of Cryptococcus Neoformans From Pigeon Droppings In Ahwaz, Iran, Majid Zarrin, Masoomeh Jorfi, Nasrin Amirrajab, Morad Rostami
Isolation Of Cryptococcus Neoformans From Pigeon Droppings In Ahwaz, Iran, Majid Zarrin, Masoomeh Jorfi, Nasrin Amirrajab, Morad Rostami
Turkish Journal of Medical Sciences
Cryptococcus neoformans is an opportunistic human pathogen that causes cryptococcosis, a life-threatening infection that is usually manifested as menigeoencephalitis mainly in immunocompromised patients. The objective of this study was to evaluate the presence of Cryptococcus neoformans in Ahwaz, Iran. Materials and methods: Sixty-five samples of pigeon droppings were collected from 10 different regions in Ahwaz. Each sample was suspended 1:10 in saline solution and then cultured in Sabouraud's dextrose agar medium including chloramphenicol. Identification of C. neoformans was performed on the basis of melanin synthesis on bird seed agar, presence of a capsule on India ink preparation, urease production on …
Association Between Prepregnancy Body Mass Index, Gestational Weight Gain, And Perinatal Outcomes, İlknur İnegöl Gümüş, Feri̇dun Karakurt, Ayşe Kargili, Ni̇lgün Öztürk Turhan, Mehtap Erkmen Uyar
Association Between Prepregnancy Body Mass Index, Gestational Weight Gain, And Perinatal Outcomes, İlknur İnegöl Gümüş, Feri̇dun Karakurt, Ayşe Kargili, Ni̇lgün Öztürk Turhan, Mehtap Erkmen Uyar
Turkish Journal of Medical Sciences
We aimed to investigate the effects of prepregnancy body mass index (BMI) and excess gestational weight gain on maternal-fetal outcomes. Materials and methods: Obstetrics records of 537 singleton pregnants delivered at our institution were reviewed. According to BMI, the patients were divided into 3 groups, namely, Group 1: normal (BMI 20-24.9 kg/m^2) (n = 394); Group 2: overweight (BMI 25-29.9 kg/m^2) (n = 112); Group 3: Obese (BMI > 30 kg/m^2) (n = 31). According to gestational weight gain, the subjects divided into 2 categories, namely, Group A: 8-15.9 kg weight gain (n = 326); Group B: >16kg weight gain (n …
Trace Elements And Physical Activity In Children And Adolescents With Depression, M. Meti̇n Donma, Orki̇de Donma
Trace Elements And Physical Activity In Children And Adolescents With Depression, M. Meti̇n Donma, Orki̇de Donma
Turkish Journal of Medical Sciences
Depression is a common mental health problem among adolescents. Depressive symptoms are also important and may appear even during the preschool period. Physical activity, which may improve some mental health problems, is inversely associated with depression. Due to the presence of some clinical evidence about the relation between the use of antidepressants and suicide, there is a need for supportive agents during antidepressant therapy. Within this context, essential trace elements gain importance for further consideration. Protection of the developing brain from the negative effects of iron deficiency is important because of iron deficiency's association with poor mental development. Reactions between …
Effects Of Three Different Methods Of Anesthesia On The Release Of Brain Natriuretic Peptid In Patients With Cardiac Risk Undergoing Lower Extremity Surgery, Canan Atalay, Celaletti̇n Dağli, Ednan Bayram, Haci Ahmet Alici, Ali̇ Fuat Erdem, Mevlüt Sai̇t Keleş, Şahi̇n Yüksek
Effects Of Three Different Methods Of Anesthesia On The Release Of Brain Natriuretic Peptid In Patients With Cardiac Risk Undergoing Lower Extremity Surgery, Canan Atalay, Celaletti̇n Dağli, Ednan Bayram, Haci Ahmet Alici, Ali̇ Fuat Erdem, Mevlüt Sai̇t Keleş, Şahi̇n Yüksek
Turkish Journal of Medical Sciences
To investigate if intra and postoperative thoracal epidural analgesia could decrease plasma concentrations of brain natriuretic peptide (BNP) in patients who were at risk for, or had, coronary artery disease (CAD) and undergoing lower extremity operations. Materials and methods: Sixty patients with risk of CAD scheduled to undergo lower extremity surgery were divided into 3 groups. Group G was administered general anesthesia followed by intravenous patient-controlled analgesia (I.V PCA) (n = 20). Group L was administered lumbar epidural anesthesia followed by lumbar epidural analgesia (n = 20). Group T was administered general anesthesia combined with intra and postoperative thoracal epidural …
X-Ray Diffraction Analysis Of Urinary Tract Stones, Turgut Yapanoglu, Azam Demi̇rel, Şenol Adanur, Hi̇kmet Yüksel, Özkan Polat
X-Ray Diffraction Analysis Of Urinary Tract Stones, Turgut Yapanoglu, Azam Demi̇rel, Şenol Adanur, Hi̇kmet Yüksel, Özkan Polat
Turkish Journal of Medical Sciences
To analyze urinary tract stones obtained in our clinic using various methods and to determine the spectrum of stone composition in the Eastern Anatolia Region, Turkey. Materials and methods: A total of 300 stones were obtained at Atatürk University, Faculty of Medicine Urology Clinic through open surgery, percutaneous nephrolithotomy (PNL), ureterorenoscopy (URS), and extracorporeal shock-wave lithotripsy (ESWL) between 1 January 2005 and 30 December 2008. Stones were analyzed in the laboratory of Ankara General Directorate of Mineral Research Exploration using X-ray diffraction (XRD). Results: It was found that 218 (72.7%) of the 300 stones were calcium oxalate (CaOx); 170 (56.7%) …
Psychological Characteristics Of Adolescent Suicide Attempters Presenting To A Pediatric Emergency Service, Di̇lek Di̇lli̇, Yildiz Dallar, İlyas Çakir
Psychological Characteristics Of Adolescent Suicide Attempters Presenting To A Pediatric Emergency Service, Di̇lek Di̇lli̇, Yildiz Dallar, İlyas Çakir
Turkish Journal of Medical Sciences
To determine the sociodemographic and behavioral characteristics of adolescents who attempt suicide and evaluate them by different scales. Materials and methods: The study was conducted with 116 adolescent suicide attempters and 98 age-matched healthy controls. Results: The mean age of all adolescents was 13.8 ± 1.2 years, with ages ranging from 11 to 16 years. Of these adolescents, 82.7% were girls. The total Suicide Probability Scale score was negatively correlated with the total Reasons for Living Inventory (r = -0.42, P = 0.001) and positively correlated with the Problem Solving Inventory score, which is indicative of low problem-solving capabilities (r …
Effect Of Viscum Album On Acute Hepatic Damage Caused By Carbon Tetrachloride In Rats, Omar Mohamed Abdel-Salam, Amany Ameen Sleem, Nermeen M. Shaffie
Effect Of Viscum Album On Acute Hepatic Damage Caused By Carbon Tetrachloride In Rats, Omar Mohamed Abdel-Salam, Amany Ameen Sleem, Nermeen M. Shaffie
Turkish Journal of Medical Sciences
To investigate the effect of Viscum album, a plant used for the treatment of hepatocellular carcinoma that has immune-modulating properties, on acute hepatic injury in rats. Materials and methods: Hepatotoxicity was induced by CCl_4 orally (0.28 mL/kg). Rats received either Viscum album at 1 of 2 dose levels (0.1 or 0.2 mL/kg) once weekly subcutaneously alone or with silymarin (25 mg/kg, orally), or silymarin (25 mg/kg) once daily orally for 1 month, starting at the time of administration of CCl_4. Liver damage was assessed by determining liver serum enzyme activities and by hepatic histopathology. Results: Viscum album administration decreased the …
Insertions Of The Lateral Pterygoid Muscle To The Disc-Capsule Complex Of The Temporomandibular Joint And Condyle, Cenk Kiliç, Gühan Dergi̇n, Fati̇h Yazar, Bülent Kurt, Tunç Kutoğlu, Hasan Ozan, Hüseyi̇n Avni̇ Balcioğlu
Insertions Of The Lateral Pterygoid Muscle To The Disc-Capsule Complex Of The Temporomandibular Joint And Condyle, Cenk Kiliç, Gühan Dergi̇n, Fati̇h Yazar, Bülent Kurt, Tunç Kutoğlu, Hasan Ozan, Hüseyi̇n Avni̇ Balcioğlu
Turkish Journal of Medical Sciences
To investigate the disc-capsule complex and condyle attachments of the lateral pterygoid muscle and its variations. Materials and methods: Forty-nine temporomandibular joint (TMJ) specimens were used, obtained from 26 human cadavers. The insertion point of each muscle head was determined. The widths and lengths of the heads were measured. Results: In 32 specimens, 2-headed muscles were present, while 3 heads were observed in 17 specimens. We defined 4 different types of attachments of muscle heads. In the most common type of attachment, the upper head inserted into the disc-capsule complex and condyle, and the lower head inserted into the condyle …
An Application Of Nonlinear Canonical Correlation Analysis On Medical Data, Ayşe Canan Yazici, Ersi̇n Öğüş, Handan Ankarali, Fi̇kret Gürbüz
An Application Of Nonlinear Canonical Correlation Analysis On Medical Data, Ayşe Canan Yazici, Ersi̇n Öğüş, Handan Ankarali, Fi̇kret Gürbüz
Turkish Journal of Medical Sciences
In studies in the field of medicine, necessity to examine the relations between data sets composed of categorical variable groups is widely encountered. In this study, it was aimed to examine nonlinear canonical correlation analysis (OVERALS) method, which allows examination of relations among K number of categorical variable sets and structural similarities of the data set, and to discuss usefulness of the method in more comprehensive data sets obtained from studies carried out in the field of medicine in terms of practice and interpretation. Materials and methods: OVERALS method was applied to a part of data set obtained from a …
Comparison Of Quality Of Life In Hepatitis B Virus Carriers Versus Chronic Hepatitis B Virus Carriers Versus The Normal Population, Meltem Işikgöz Taşbakan, Özen Önen Sertöz, Hüsnü Pullukçu, Şebnem Çalik, Oğuz Reşat Si̇pahi̇, Tansu Yamazhan
Comparison Of Quality Of Life In Hepatitis B Virus Carriers Versus Chronic Hepatitis B Virus Carriers Versus The Normal Population, Meltem Işikgöz Taşbakan, Özen Önen Sertöz, Hüsnü Pullukçu, Şebnem Çalik, Oğuz Reşat Si̇pahi̇, Tansu Yamazhan
Turkish Journal of Medical Sciences
To compare health related quality of life (HRQOL) in hepatitis B virus (HBV) carriers versus chronic HBV disease carriers versus the normal population. Materials and methods: The study sample consisted of 2 groups. HBV carriers were recruited from individuals who were regularly followed-up at the Infectious Diseases and Clinical Microbiology outpatient clinic of our setting due to inactivity in HBV infection. The control group was recruited from the same outpatient clinic among patients who had a diagnosis of chronic HBV infection and who were not undergoing active treatment yet. Both groups were requested to fill in the short form 36 …
A Novel Cut-Off For Abdominal Obesity Derived From Various Anthropometric Indices To Predict Body Composition: Arm Fat Area, Betül Çi̇çek, Ahmet Öztürk, Mümtaz M. Mazicioğlu, Neri̇man İnanç, Seli̇m Kurtoğlu
A Novel Cut-Off For Abdominal Obesity Derived From Various Anthropometric Indices To Predict Body Composition: Arm Fat Area, Betül Çi̇çek, Ahmet Öztürk, Mümtaz M. Mazicioğlu, Neri̇man İnanç, Seli̇m Kurtoğlu
Turkish Journal of Medical Sciences
Determination of fat and fat-free mass is of considerable interest in evaluation of nutritional status. The aim of the present study was to determine whether using arm fat area (AFA) is helpful in identifying abdominal obesity (waist circumference > 90^{th} percentile) in Turkish children and adolescents with high risk. According to AFA ≥ 85^{th} percentile indicating overweight, we determined age- and gender-specific cut-offs from anthropometric indices. Materials and methods: This study was conducted with 5358 (2621 boys, 2737 girls) children and adolescents aged 6-17 years. Height, weight, arm span, waist circumference (WC), mid-upper arm circumference (MUAC), and triceps skinfold thickness (TSF) …
Correlation Between Increased Urinary Serotonin Levels And Coronary Artery Disease In Cigarette Smoking Patients, Necat Yilmaz, Yakup Mermerdaş, Esi̇n Eren, Ayşenur Yeği̇n, Emi̇ne Namiduru
Correlation Between Increased Urinary Serotonin Levels And Coronary Artery Disease In Cigarette Smoking Patients, Necat Yilmaz, Yakup Mermerdaş, Esi̇n Eren, Ayşenur Yeği̇n, Emi̇ne Namiduru
Turkish Journal of Medical Sciences
Platelets secrete serotonin (5-hydroxytryptamine), which has several effects on the vascular wall and promotes thrombogenesis, mitogenesis, and the proliferation of smooth muscle cells. We therefore measured excreted levels of 5-hydroxytryptamine (5-HT) concentrations in urine as a means of assessing vascular lesions in patients with coronary artery disease ( CAD). Materials and methods: Subjects who underwent coronary angiography were classified into 2 groups according to their diagnosis. The CAD group consisted of 33 patients with coronary artery stenosis, whereas the healthy control group consisted of 30 subjects. An isocratic high-performance liquid chromatographic (HPLC) system with an electrochemical detector was used for …
Caustic Esophageal Injury Decreases The Number Of Interstitial Cells Of Cajal In The Rat Esophagus, Tutku Soyer, Şebnem Ayva, Sali̇h Somuncu, Pinar Atasoy, Turan Kanmaz, Murat Çakmak
Caustic Esophageal Injury Decreases The Number Of Interstitial Cells Of Cajal In The Rat Esophagus, Tutku Soyer, Şebnem Ayva, Sali̇h Somuncu, Pinar Atasoy, Turan Kanmaz, Murat Çakmak
Turkish Journal of Medical Sciences
To evaluate the effect of caustic esophageal injury (CEI) on the number of interstitial cells of Cajal (ICC). Materials and methods: Wistar rats were divided into 3 groups: control, acid, and alkali induced CEI. CEI was performed by the injection of 1 mL of 10% hypochloric acid in the acid group, and 1 mL of 10% sodium hydroxide was injected into the alkali group. Distal esophageal segments were removed 24 h after injection. CEI was graded and the number of ICC were investigated (CD-117 staining). The number of ICC was compared in groups and correlated with CEI grades. Results: Typical …
The Comparison Of Mri Findings With Severity Score Of Incontinence After Pubovaginal Sling Surgery, Serdar Tarhan, Bi̇lali̇ Gümüş, Gökhan Temeltaş, Gülgün Yilmaz Ovali, Seli̇m Serter, Ci̇han Göktan
The Comparison Of Mri Findings With Severity Score Of Incontinence After Pubovaginal Sling Surgery, Serdar Tarhan, Bi̇lali̇ Gümüş, Gökhan Temeltaş, Gülgün Yilmaz Ovali, Seli̇m Serter, Ci̇han Göktan
Turkish Journal of Medical Sciences
To investigate the relationship between postoperative MRI findings and the severity score of incontinence in patients treated with pubovaginal sling surgery. Materials and methods: Fifty-two female patients treated with pubovaginal slings were included in the study. These patients' severity scores of incontinence were evaluated in the postoperative 6th month. All the patients were examined using MRI on the same day. A T2-weighted sagittal image of the midline structures, including the symphysis, urethra, and coccyx, was obtained at rest and at maximal strain. The mobility of the bladder floor and change in the posterior urethrovesical angle were calculated for each patient. …
The Comprehensive Evaluation Of Latent Tuberculosis Infection In Health Care Workers And Of Patients With Active Tuberculosis Using Tst, Elisa, And Elispot Methods, Hülya Şi̇mşek, Si̇bel Meryem Alpar, Kurtuluş Aksu, Funda Aksu, İsmai̇l Ceyhan, Sali̇h Cesur, Ayşegül Gözalan, Mustafa Ertek
The Comprehensive Evaluation Of Latent Tuberculosis Infection In Health Care Workers And Of Patients With Active Tuberculosis Using Tst, Elisa, And Elispot Methods, Hülya Şi̇mşek, Si̇bel Meryem Alpar, Kurtuluş Aksu, Funda Aksu, İsmai̇l Ceyhan, Sali̇h Cesur, Ayşegül Gözalan, Mustafa Ertek
Turkish Journal of Medical Sciences
Until recently, the tuberculin skin test (TST) has been the only assay used for detecting latent tuberculosis infection (LTBI), but two ex-vivo tests, used as alternative methods to TST, based on enumerating the M. tuberculosis-specific interferon (IFN)-\gamma response are now commercially licensed. The aim of this study was to compare the sensitivity and specificity of TST, QuantiFERON Gold (QFT-G), and T-SPOT.TB in diagnosing LTBI and active tuberculosis (TB). Materials and methods: This study was carried out with 95 participants including 3 groups (negative control, close contact, and patient groups) during a 10-month period from March 2007 to January 2008. Results: …
The Prevalence Of Home Injuries Among Elderly People In Samsun, Turkey, And The Influencing Factors, Hülya Doğan, Sevgi̇ Canbaz, Berna Tander, Yildiz Pekşen, Ferhan Cantürk, Ni̇met Özal Oruç
The Prevalence Of Home Injuries Among Elderly People In Samsun, Turkey, And The Influencing Factors, Hülya Doğan, Sevgi̇ Canbaz, Berna Tander, Yildiz Pekşen, Ferhan Cantürk, Ni̇met Özal Oruç
Turkish Journal of Medical Sciences
Home injuries are a serious public health problem for the elderly. Our aim was to investigate the prevalence of home injuries among elderly people in Samsun, Turkey, and the influencing factors. Materials and methods: This cross-sectional study was conducted between 1 January and 28 February 2007. A questionnaire, the Home-Screen Scale (HSS), and the Geriatric Depression Scale (GDS) were administered to the elderly subjects. Results: Of all participants, 20.6% had experienced some kind of home injury. Seven participants living alone and 14 living with their families had suffered home injuries, suggesting a statistically significant difference between these 2 groups (P < 0.05). Eleven (14.7%) subjects living in secure housing and 10 (37.0%) living in unsecure housing had suffered home injuries, the difference again being statistically significant (P < 0.05). Conclusion: Home injuries are more common among people living alone and in unsecure housing according to the HSS.
Allele Distribution Data For 16 Short Tandem Repeat Loci In Bolu, Ayşi̇m Tuğ, Zerri̇n Erkol, Aysun Çeti̇nyürek, Yeşi̇m Doğan Alakoç, Cüneyt Elma, Bora Büken, Hayri̇ Erkol
Allele Distribution Data For 16 Short Tandem Repeat Loci In Bolu, Ayşi̇m Tuğ, Zerri̇n Erkol, Aysun Çeti̇nyürek, Yeşi̇m Doğan Alakoç, Cüneyt Elma, Bora Büken, Hayri̇ Erkol
Turkish Journal of Medical Sciences
To examine the short tandem repeat (STR) data of Bolu population and compare the data with previously published population studies and with the data of a neighboring province, Düzce (a former district of Bolu), which became a province after the earthquake in 1999. Materials and methods: Blood samples were taken from 175 unrelated individuals. DNA was isolated using a DNA Kit and the amplification was performed using an AmpFlSTR Identifier kit. Genotyping was carried out by an ABI Prism 310 genetic analyzer by using a reference ladder. Several parameters, such as allele frequencies, Hardy-Weinberg equilibrium, power of exclusion, power of …
Peritoneal Dialysis-Related Peritonitis: An Analysis Of Risk Factors In Northeast Anatolia*, Mustafa Keleş, Ramazan Çeti̇nkaya, Abdullah Uyanik, Hami̇t Acemoğlu, Fatma Saatçi, Muhammet Hami̇dullah Uyanik
Peritoneal Dialysis-Related Peritonitis: An Analysis Of Risk Factors In Northeast Anatolia*, Mustafa Keleş, Ramazan Çeti̇nkaya, Abdullah Uyanik, Hami̇t Acemoğlu, Fatma Saatçi, Muhammet Hami̇dullah Uyanik
Turkish Journal of Medical Sciences
Peritonitis is almost the most frequent complication of peritoneal dialysis (PD). Besides being the most frequent reason of hospitalization, peritonitis is also the most important determining factor of mortality-morbidity and technique survival among PD patients. In this study, it was aimed to identify the risk factors for peritonitis in these patients. Materials and methods: In this clinical cohort, records of 218 patients were collected between January 1998 and December 2007. The patients’ demographic, clinical, and laboratory parameters were recorded. Results were analyzed to compare patients who never had peritonitis and patients with at least one episode of peritonitis. Independent predictors …
Does Central Corneal Thickness Correlate With Haemoglobin A1c Level And Disease Severity In Diabetes Type Ii?, Mehmet Özgür Zengi̇n, Zeynep Özbek, Gül Arikan, İsmet Durak, Ali̇ Osman Saatci̇
Does Central Corneal Thickness Correlate With Haemoglobin A1c Level And Disease Severity In Diabetes Type Ii?, Mehmet Özgür Zengi̇n, Zeynep Özbek, Gül Arikan, İsmet Durak, Ali̇ Osman Saatci̇
Turkish Journal of Medical Sciences
To compare central corneal thickness (CCT) values of patients with type II diabetes mellitus with those of healthy subjects, and evaluate the effect of disease duration, retinopathy severity, and HbA1c level on CCT. Materials and methods: One hundred and twenty-six consecutive type II diabetic patients and 36 non-diabetic healthy subjects were included in the study. CCT was measured using the Orbscan II corneal topography system. The effect of disease duration, retinopathy severity, and HbA1c level on CCT was evaluated using analysis of variance (ANOVA) and the independent sample t test. Results: CCT was significantly higher in diabetic patients than in …
The Effects Of 3-Benzoyl-1-Methyl-4-Phenyl-4 Piperidinolhydrochloride (C1), Indomethacin, Nimesulide And Rofecoxib On Cyclooxygenase Activities In Carrageenan-Induced Paw Edema Model, Yaşar Nuri̇ Şahi̇n, Berna Demi̇rcan, Hali̇s Süleyman, Hülya Aksoy, Hali̇se İnci̇ Gül
The Effects Of 3-Benzoyl-1-Methyl-4-Phenyl-4 Piperidinolhydrochloride (C1), Indomethacin, Nimesulide And Rofecoxib On Cyclooxygenase Activities In Carrageenan-Induced Paw Edema Model, Yaşar Nuri̇ Şahi̇n, Berna Demi̇rcan, Hali̇s Süleyman, Hülya Aksoy, Hali̇se İnci̇ Gül
Turkish Journal of Medical Sciences
The aim of this study was to investigate the effects of 3-benzoyl-1-methyl-4-phenyl-4-piperidinol-hydrochloride (C1), which is a structural and also non-classical isomer of bis Mannich base, bis (3-aryl-3-oxo-propyl) methylamine hydrochlorides (B1), on cyclooxygenase (COX) activities in 48 rats with inflammation by using carrageenan-induced paw edema, and to compare its effect with other non-steroidal anti-inflammatory drugs (NSAIDs). Materials and methods: Experimental animals were supplied by the Center of Experimental Research and Practice in Ataturk University. The animals were housed and fed in the laboratory (normal room temparature, food and water) under standard conditions. Rats were randomly assigned to eight groups (n = …
Serum Prolidase Activity In Patients With Degenerative And Rheumatic Heart Valve Diseases, Murat Bülent Rabuş, Recep Demi̇rbağ, Yusuf Sezen, Mehmet Taşar, Abdullah Taşkin, Nurten Aksoy, Kaan Kirali̇, Cevat Yakut
Serum Prolidase Activity In Patients With Degenerative And Rheumatic Heart Valve Diseases, Murat Bülent Rabuş, Recep Demi̇rbağ, Yusuf Sezen, Mehmet Taşar, Abdullah Taşkin, Nurten Aksoy, Kaan Kirali̇, Cevat Yakut
Turkish Journal of Medical Sciences
It is known that renin-angiotensin system, inflammation, signaling pathways, and genetic predisposition play a major role in the pathogenesis of heart valve disease. Scarring and collagen deposition in the valves and destruction of myocytes may result from the combined effects of rheumatic and degenerative process in heart valve diseases. Prolidase plays an important role in collagen metabolism, matrix remodeling and cell growth. The aim of the study was to comparatively assess the serum prolidase activity in rheumatic and degenerative heart valve diseases. Materials and methods: The study included 26 patients who had undergone valve replacement due to rheumatic etiology (Group …
The Distribution Of Telomerase Activity In Patients With Helicobacter Pylori Positive Gastritis, Nai̇me Canoruç, Ebru Kale, Şeri̇f Yilmaz, Kadi̇m Bayan, Mehmet Dursun, Sabri̇ Batun, Abdurrahman Kaplan
The Distribution Of Telomerase Activity In Patients With Helicobacter Pylori Positive Gastritis, Nai̇me Canoruç, Ebru Kale, Şeri̇f Yilmaz, Kadi̇m Bayan, Mehmet Dursun, Sabri̇ Batun, Abdurrahman Kaplan
Turkish Journal of Medical Sciences
Helicobacter pylori is considered a class I carcinogen by the World Health Organization. We aimed to determine whether H. pylori has an effect on telomerase activity in patients with H. pylori related non-specific gastritis, atrophy, and intestinal metaplasia. Materials and methods: One hundred and seventy-two adult patients who underwent upper gastroduodenoscopy were enrolled in the study. Three biopsy specimens were taken from the antrum: 1 from the incisura angularis and 2 from the mid-antrum. Biopsy specimens taken from the incisura angularis were evaluated using the urease test for detection of H. pylori. The mid-antrum specimens were sent for histopathology and …
Effect Of Mechanical Closure Of Dead Space On Seroma Formation In Modified Radical Mastectomy, Ci̇hangi̇r Özaslan, Keri̇m Bora Yilmaz, Lütfi̇ Doğan, Can Atalay, Mehmet Altinok
Effect Of Mechanical Closure Of Dead Space On Seroma Formation In Modified Radical Mastectomy, Ci̇hangi̇r Özaslan, Keri̇m Bora Yilmaz, Lütfi̇ Doğan, Can Atalay, Mehmet Altinok
Turkish Journal of Medical Sciences
Seroma is an important complication of breast surgery. This study investigated the effects of fixation of the flaps and obliterating the dead space on seroma formation. Materials and methods: Patients undergoing modified radical mastectomy were separated into 2 random groups of 50 according to wound closure methods: either flap fixation/mechanical obliteration or standard wound closure group. The fluid that collected under the flaps assessed at the physical examination after the drains were removed was accepted as seroma. The patients' characteristics, duration of the operation, drainage amount, removal time of the drains, flap necroses, and infection were recorded. The groups were …