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Articles 4201 - 4230 of 8080
Full-Text Articles in Medicine and Health Sciences
The Effects Of Antioxidants On Testicular Apoptosis And Oxidative Stress Produced By Cell Phones, Aki̇f Koç, Doğan Ünal, Ersi̇n Çi̇mentepe, Ömer Bayrak, Ömer Faruk Karataş, Mehmet Erol Yildirim, Reyhan Bayrak, Murat Aydin
The Effects Of Antioxidants On Testicular Apoptosis And Oxidative Stress Produced By Cell Phones, Aki̇f Koç, Doğan Ünal, Ersi̇n Çi̇mentepe, Ömer Bayrak, Ömer Faruk Karataş, Mehmet Erol Yildirim, Reyhan Bayrak, Murat Aydin
Turkish Journal of Medical Sciences
The aim of this study was to determine the probable effects of cellular phone usage on apoptosis and oxidative/antioxidative balance in testicular tissue, and the probable protective role of vitamin C and E on these processes. Materials and methods: Forty-two male rats were divided into 6 groups: control, antioxidant, calling, stand-by, calling plus antioxidant, and stand-by plus antioxidant. Oxidant and antioxidant parameters and apoptotic indexes were studied. Two identical cell phones were used in the calling and stand-by groups. Results: Cell phone usage significantly increased apoptosis in call, but not in the stand-by position, in testicular tissue. Apoptosis produced in …
Effectiveness Of Hp-Hmg Versus R-Fsh In Patients Undergoing Ivf/Icsi Cycles With Moderate Male-Factor Infertility, Ni̇lgün Turhan, Aslihan Pekel, Ayli̇n Ayrim, Burcu Kasap, Ömer Bayrak
Effectiveness Of Hp-Hmg Versus R-Fsh In Patients Undergoing Ivf/Icsi Cycles With Moderate Male-Factor Infertility, Ni̇lgün Turhan, Aslihan Pekel, Ayli̇n Ayrim, Burcu Kasap, Ömer Bayrak
Turkish Journal of Medical Sciences
The aim of this case-control study was to compare the efficacy of highly purified human menopausal gonadotropin (HP-hMG) versus recombinant follicle stimulating hormone (r-FSH) treatments following gonadotropin-releasing hormone (GnRH) agonist suppression in patients undergoing intracytoplasmic sperm injection (ICSI) with moderate male-factor infertility in terms of oocyte and embryo quality and clinical pregnancy outcomes. Materials and methods: A total of 240 infertile women were treated with HP-hMG (HP-hMG group, n = 120 patients) or r-FSH (r-FSH group, n = 120 patients) following GnRH agonist suppression (long regimen). Inclusion criteria for the study groups were infertility due to moderate oligoasthenoteratospermia with no …
Preliminary Data From A Surveillance Study On Surgical Site Infections And Assessment Of Risk Factors In A University Hospital, Mustafa Namiduru, İlkay Karaoğlan, Riza Çam, Vuslat Boşnak, Ayşe Özlem Mete
Preliminary Data From A Surveillance Study On Surgical Site Infections And Assessment Of Risk Factors In A University Hospital, Mustafa Namiduru, İlkay Karaoğlan, Riza Çam, Vuslat Boşnak, Ayşe Özlem Mete
Turkish Journal of Medical Sciences
Surgical site infections (SSIs) lead to substantial mortality, morbidity, and socioeconomic loss. To explore the rate of infections and risk factors for the development of infection in surgical units. Materials and methods: All patients (n = 1397) who underwent a surgical intervention and were hospitalized for >48 h in surgical units (except the ophthalmology unit) of Gaziantep University Medical Faculty Hospital between 17 March 2008 and 15 July 2008 were included in the study. The Center for Disease Control and Prevention criteria were used for identifying and diagnosing SSIs. Rate of SSI was calculated as the number of SSIs observed …
The Role Of Vitamin D Deficiency In Parathyroid Hormone Levels, Alpaslan Kiliçarslan, Alma Cenoli̇ Aslan, Gamze Gezgen
The Role Of Vitamin D Deficiency In Parathyroid Hormone Levels, Alpaslan Kiliçarslan, Alma Cenoli̇ Aslan, Gamze Gezgen
Turkish Journal of Medical Sciences
Vitamin D deficiency is an important cause of secondary hyperparathyroidism. We aimed to investigate the effect of vitamin D levels on parathyroid hormone (PTH) levels. Materials and methods: We retrospectively chose 2226 patients who were admitted to our hospital’s general internal medicine department for various reasons and had both PTH and vitamin D tests on the same day. Results: It was found that 22.3% of the patients had high levels of PTH and 92% of them had secondary hyperparathyroidism. The average vitamin D level was 16.4 ng/mL. The vitamin D levels of 64% of the patients were below 20 ng/mL …
Effect Of The Presence Of Pneumonia On Noninvasive Ventilation Success In Chronic Obstructive Pulmonary Disease Cases With Acute Hypercapnic Respiratory Failure, Serdar Akpinar, Kazim Rollas, Evri̇m Eylem Akpinar, Ali̇ Alagöz, Nazi̇re Uçar, Yusuf Tuğrul Şi̇pi̇t
Effect Of The Presence Of Pneumonia On Noninvasive Ventilation Success In Chronic Obstructive Pulmonary Disease Cases With Acute Hypercapnic Respiratory Failure, Serdar Akpinar, Kazim Rollas, Evri̇m Eylem Akpinar, Ali̇ Alagöz, Nazi̇re Uçar, Yusuf Tuğrul Şi̇pi̇t
Turkish Journal of Medical Sciences
To investigate the effect of the presence of pneumonia on the success of noninvasive mechanical ventilation (NIMV) in chronic obstructive pulmonary disease (COPD) cases with acute respiratory failure. Materials and methods: Sixty patients admitted to the intensive care unit (ICU) due to COPD exacerbation were included. The patients were divided into 2 groups as those with pneumonia (Group 1) and without pneumonia (Group 2). According to initial pH values, cases were also divided into 3 subgroups based on pH values. C-reactive protein (CRP), APACHE II scores, requirement of endotracheal intubation, mortality, and duration of ICU and hospital stay were also …
Measurement Of The In-Air Output Ratio For High-Energy Photon Beams Used In Radiotherapy, Murugan Appasamy, Sidonia Valas Xavier, Thayalan Kuppusamy, Ramasubrmanian Velayudham
Measurement Of The In-Air Output Ratio For High-Energy Photon Beams Used In Radiotherapy, Murugan Appasamy, Sidonia Valas Xavier, Thayalan Kuppusamy, Ramasubrmanian Velayudham
Turkish Journal of Medical Sciences
To measure the in-air output ratio of a 15-MV photon beam using locally designed miniphantoms. Materials and methods: Columnar and brass miniphantoms were designed locally to accommodate 0.6 cc and 0.13 cc ionization chambers. The in-air output ratio (S_C) was measured for square, rectangular, and wedged fields for 15 MV. The influences of the orientation of the miniphantom, miniphantom material, and chamber volume on S_C and the collimator exchange effect were also studied. Results: The S_C measurements ranged from 0.944 to 1.0321 for the studied field sizes. The orientation of the miniphantom had no influence on S_C for the range …
Do Characteristics Of Seriously Injured Older Adults Differ From Those Of Their Younger Counterparts In The Emergency Department?, Ayhan Aköz, Memet Işik, Hüseyi̇n Şahi̇n, Mücahi̇t Emet
Do Characteristics Of Seriously Injured Older Adults Differ From Those Of Their Younger Counterparts In The Emergency Department?, Ayhan Aköz, Memet Işik, Hüseyi̇n Şahi̇n, Mücahi̇t Emet
Turkish Journal of Medical Sciences
To analyze the injury characteristics of younger and older adult trauma victims. Materials and methods: This was a prospective, cross-sectional, observational, and single-center study including both younger adult and geriatric trauma patients. The relationships between the age groups and the number of consultations in the emergency department (ED) were compared with analysis of covariance after adjusting for Injury Severity Score (ISS). Results: The data consisted of 779 patients, 131 (16.8%) of whom were elderly. The intensive care unit admission rate was 7.2%. Our results showed a significantly higher incidence of intracranial hemorrhage, fracture and/or dislocation of the femur, and fracture …
Comparing Extracorporeal Shock Wave And Hyaluronic Acid In A Rabbit Cartilage Defect Model: The Effects Of Esw On Cartilage Defect, Zekeri̇ya Öztemür, Hati̇ce Özer, Umut Hatay Gölge, Emi̇ne Eli̇f Altuntaş, Okay Bulut
Comparing Extracorporeal Shock Wave And Hyaluronic Acid In A Rabbit Cartilage Defect Model: The Effects Of Esw On Cartilage Defect, Zekeri̇ya Öztemür, Hati̇ce Özer, Umut Hatay Gölge, Emi̇ne Eli̇f Altuntaş, Okay Bulut
Turkish Journal of Medical Sciences
To compare the efficiency of extracorporeal shock wave (ESW) treatment with hyaluronic acid (HA) viscosupplementation in an experimental rabbit cartilage defect model. Materials and methods: A total of 24 New Zealand rabbits were randomly divided into 4 groups: HA, ESW, ESW + HA, and control. Chondral defects were created in the left knees of the rabbits. HA viscosupplementation was performed on the HA and ESW + HA groups, and after 24 h, 0.16 mJ/mm2 ESW was performed on the ESW and ESW + HA groups. After an 8-week follow-up, the rabbits were sacrificed and histopathological examination of the defects was …
The Effect Of Addition Of Lidocaine To Bupivacaine On Anesthesia Beginning Time, Block Time, And Block Quality In Lateral Sagittal Infraclavicular Block, Özgür Özmen, Haci Ahmet Alici, Mi̇ne Çeli̇k, Ayşenur Dostbi̇l, Mehmet Cesur
The Effect Of Addition Of Lidocaine To Bupivacaine On Anesthesia Beginning Time, Block Time, And Block Quality In Lateral Sagittal Infraclavicular Block, Özgür Özmen, Haci Ahmet Alici, Mi̇ne Çeli̇k, Ayşenur Dostbi̇l, Mehmet Cesur
Turkish Journal of Medical Sciences
To investigate whether a 2% lidocaine addition to 0.5% bupivacaine that is used in a lateral sagittal infraclavicular block, when administered in an upper extremity surgery, decreases the block onset time, drug effect time, and drug activity when compared with bupivacaine alone. Materials and methods: This study was performed on 120 American Society of Anesthesiology classification I-II patients who were 18–65 years old and scheduled to undergo an upper extremity surgery. The group testing in the study was as follows: 20 mL (5 mg/mL) bupivacaine, 10 mL (5 mg/mL) bupivacaine + 10 mL (20 mg/mL) lidocaine, and 20 mL (20 …
The Effect Of Preemptive Thoracic Epidural Analgesia On Long-Term Wound Pain Following Major Thoracotomy, Abdullah Can, Ali̇ Fuat Erdem, Yener Aydin, Ali̇ Ahiskalioğlu, Hüsnü Kürşad
The Effect Of Preemptive Thoracic Epidural Analgesia On Long-Term Wound Pain Following Major Thoracotomy, Abdullah Can, Ali̇ Fuat Erdem, Yener Aydin, Ali̇ Ahiskalioğlu, Hüsnü Kürşad
Turkish Journal of Medical Sciences
To evaluate the effects of the performance of preemptive epidural analgesia in major thoracotomies on chronic postthoracotomy pain. Materials and methods: A total of 60 patients with ASA I-II status between the ages of 18 and 75 years who planned to have elective thoracotomy were randomized into 3 groups. In all cases, an epidural catheter was placed at the 6th–7th or 7th–8th thoracic intervals, preoperatively. Patients in the control group (n = 20) did not receive epidural analgesics before and during the operation, and preoperative analgesia was provided by remifentanil infusion. In the incision-sensitized group (n = 20), patients had …
Pcr Detection Of Brucella Abortus In Cow Milk Samples Collected From Erzurum, Turkey, Tüli̇n Arasoğlu, Medi̇ne Güllüce, Hakan Özkan, Ahmet Adigüzel, Fi̇kretti̇n Şahi̇n
Pcr Detection Of Brucella Abortus In Cow Milk Samples Collected From Erzurum, Turkey, Tüli̇n Arasoğlu, Medi̇ne Güllüce, Hakan Özkan, Ahmet Adigüzel, Fi̇kretti̇n Şahi̇n
Turkish Journal of Medical Sciences
In this study, we designed and used 2 different type-specific polymerase chain reaction (PCR) methods for the detection of Brucella abortus. Materials and methods: There were 2 different primer sets (B4/B5 and AF/AR) selected and used for the amplification of 2 different genes that are present in all biovars of Brucella species, including bcsp31, encoding 31-kDa immunogenic cell surface proteins, and omp25, which is known to be one of the virulence factors encoding outer membrane proteins of 26–23 kDa. Results: The results showed that 273 (81.7%) and 317 (94.9%) out of 334 milk samples were positive for brucellosis, as detected …
Urease Inhibitory Potential Of Zizyphus Oxyphylla Edgew. Extracts And Isolated Compounds, Waqar Ahmad Kaleem, Muhammad Nisar, Mughal Qayum, Muhammad Zia-Ul-Haq, Muhammad Iqbal Choudhary, Sezai̇ Erci̇şli̇
Urease Inhibitory Potential Of Zizyphus Oxyphylla Edgew. Extracts And Isolated Compounds, Waqar Ahmad Kaleem, Muhammad Nisar, Mughal Qayum, Muhammad Zia-Ul-Haq, Muhammad Iqbal Choudhary, Sezai̇ Erci̇şli̇
Turkish Journal of Medical Sciences
To determine the urease inhibitory potential of extracts and isolated compounds from Zizyphus oxyphylla Edgew. Materials and methods: Methanolic extracts and subsequent fractions of Z. oxyphylla stem and 3 isolated compounds from the roots of Z. oxyphylla were obtained through column chromatography and subjected to in vitro urease inhibition. Results: Three fractions (n-hexane, ethyl acetate, and butanol fractions) showed good to excellent activity, while the chloroform fraction showed nonsignificant activity. Amongst the isolated compounds, oxyphylline D (1) was the most active of the 3 isolated cyclopeptide alkaloids, followed by nummularin R (3) and nummularin C (2). Conclusion: Z. oxyphylla has …
Stereological Evaluation Of Ganglion Cells In The Sigmoid Colon In Primary And Recurrent Sigmoid Volvulus, Sabri̇ Selçuk Atamanalp, Cemal Gündoğdu, Deni̇z Ünal, Zekai̇ Halici, Abdullah Kisaoğlu, Bünyami̇ Özoğul
Stereological Evaluation Of Ganglion Cells In The Sigmoid Colon In Primary And Recurrent Sigmoid Volvulus, Sabri̇ Selçuk Atamanalp, Cemal Gündoğdu, Deni̇z Ünal, Zekai̇ Halici, Abdullah Kisaoğlu, Bünyami̇ Özoğul
Turkish Journal of Medical Sciences
To clarify the role of ganglion cells in Auerbach’s plexus of the sigmoid colon in the development and recurrence of sigmoid volvulus (SV). Materials and methods: Pathological block samples of colonic resection materials of 28 patients who underwent sigmoidectomy for SV and, for comparison, samples of 28 patients who underwent sigmoidectomy or low anterior resection for rectosigmoid cancer (RSC) were analyzed using stereological methods. Results: The mean numerical density of ganglion cells was significantly lower in the SV group than in the RSC group (140.70 mm^{-2} and 669.42 mm^{-2}, respectively, P = 0.005), whereas there was no significant difference between …
Effects Of Green Tea On Ace Gene Expression In Rat Liver In Ccl_4-Induced Cirrhosis, Syed Muhammad Shahid, Rozeena Shaikh, Sana Shamim, Muhammad Ismail, Tabassum Mahboob
Effects Of Green Tea On Ace Gene Expression In Rat Liver In Ccl_4-Induced Cirrhosis, Syed Muhammad Shahid, Rozeena Shaikh, Sana Shamim, Muhammad Ismail, Tabassum Mahboob
Turkish Journal of Medical Sciences
This study was designed to investigate the beneficial effects of green tea administration on angiotensin converting enzyme (ACE) gene expression in CCl_4-induced liver cirrhosis in rats. Materials and methods: A total of 24 male Wistar rats were divided into 3 groups as: Group 1, normal untreated rats; Group 2, CCl_4-induced cirrhotic rats; Group 3: CCl_4-induced cirrhotic + green tea treated rats. The beneficial effects of green tea were measured by alanine aminotransferase (ALT), alkaline phosphatase (ALP), total and direct bilirubin level, tissue malondialdehyde (MDA), super oxide dismutase (SOD), and catalase (CAT). The genomic DNA was isolated from excised tissue to …
Comparison Of The Protective Effects Of Desflurane And Propofol Anesthesia In Rats: A Hepatic Ischemia-Reperfusion Injury Model, Ayça Taş Tuna, Cengi̇z Beki̇r Demi̇rel, Yusuf Ünal, Aslihan Çavunt Bayraktar, Demet Yilmazer, Mustafa Kavutçu, Murat Alper, Mustafa Kerem
Comparison Of The Protective Effects Of Desflurane And Propofol Anesthesia In Rats: A Hepatic Ischemia-Reperfusion Injury Model, Ayça Taş Tuna, Cengi̇z Beki̇r Demi̇rel, Yusuf Ünal, Aslihan Çavunt Bayraktar, Demet Yilmazer, Mustafa Kavutçu, Murat Alper, Mustafa Kerem
Turkish Journal of Medical Sciences
It is known that desflurane and propofol protect liver tissue via different mechanisms. The aim of this study was to compare the protective effects of these 2 agents against hepatic ischemia-reperfusion injury. Materials and methods: Rats were randomly divided into 2 groups: ischemia and ischemia-reperfusion. Each group was further divided into 3 subgroups: ketamine, desflurane, and propofol. Thirty minutes after anesthetics were administered, the rats were subjected to 45 min of hepatic ischemia and 4 h of reperfusion. Blood samples and liver tissues were obtained in order to assess serum tumor necrosis factor alpha (TNF-\alpha), interleukin-1\beta (IL-1\beta), and malondialdehyde levels …
Sponge In The Belly; Postoperative Imaging Findings Of Oxidized Cellulose (Surgicel^®), Arzu Pampal, Gökçe Kaan Ataç, İbrahi̇m Onur Özen, Zeki̇ye Safi̇nur Keski̇n, Bi̇llur Demi̇roğullari, Sadi̇ Gündoğdu
Sponge In The Belly; Postoperative Imaging Findings Of Oxidized Cellulose (Surgicel^®), Arzu Pampal, Gökçe Kaan Ataç, İbrahi̇m Onur Özen, Zeki̇ye Safi̇nur Keski̇n, Bi̇llur Demi̇roğullari, Sadi̇ Gündoğdu
Turkish Journal of Medical Sciences
Surgicel is an absorbable material for local haemostasis. Its existence at surgical sites is troublesome since it interferes with the radiological images of postoperative complications. The aim of this study is to demonstrate the postoperative appearances of intraabdominal Surgicel. Materials and methods: Twelve guinea pigs were allocated to 2 groups. Animals with intraperitoneal (n = 6) and retroperitoneal (n = 6) Surgicel pieces were scanned postoperatively. Results: The density and intensity of Surgicel were compared with adjacent tissues. All retroperitoneal haemostats were hypointense compared to tissues next to them in T1W images but hyperintense compared to muscles, and 5 were …
Assessment Of Immune Responses To Hepatitis A Vaccination In Children Aged 1 And 2 Years, Solmaz Çelebi̇, Mustafa Kemal Hacimustafaoğlu, Yücehan Albayrak, Ayşe Melda Sinirtaş
Assessment Of Immune Responses To Hepatitis A Vaccination In Children Aged 1 And 2 Years, Solmaz Çelebi̇, Mustafa Kemal Hacimustafaoğlu, Yücehan Albayrak, Ayşe Melda Sinirtaş
Turkish Journal of Medical Sciences
Hepatitis A can be prevented by vaccination. The aim of this study was to determine seropositivity for hepatitis A before vaccination in healthy children 12 and 24 months of age and compare seroconversion rates after vaccination between these 2 groups. Materials and methods: Forty-nine children aged 1 year (Group 1) and 51 children aged 2 years (Group 2) were included in the study. Inactive hepatitis A vaccine (Avaxim, 80 antigenic subtypes, 0.5 mL) were administered to every child in 2 doses, 6 months apart. Anti-hepatitis A virus (HAV) IgG and IgM antibodies were detected by Architect HAVAb-IgG and HAVAb-IgM (Abbott, …
Diagnostic Value Of Cytokeratin 19, Hbme-1, And Galectin-3 Immunostaining Of Cell Block From Fine-Needle Aspiration Specimens In Papillary Carcinoma Of The Thyroid, Hacer Haltaş, Reyhan Bayrak, Si̇bel Yeni̇dünya, Ümran Yildirim
Diagnostic Value Of Cytokeratin 19, Hbme-1, And Galectin-3 Immunostaining Of Cell Block From Fine-Needle Aspiration Specimens In Papillary Carcinoma Of The Thyroid, Hacer Haltaş, Reyhan Bayrak, Si̇bel Yeni̇dünya, Ümran Yildirim
Turkish Journal of Medical Sciences
To evaluate the utility of immunohistochemical staining of cytokeratin 19 (CK19), HBME-1, and galectin-3 in cell block preparations of fine-needle aspiration cytology specimens as ancillary techniques for the differential diagnosis of papillary thyroid carcinoma. Materials and methods: Immunohistochemical detection of CK19, HBME-1, and galectin-3 was completed in 45 thyroid aspiration cytology specimens fixed in paraffin-embedded blocks consisting of the following cytologic diagnoses: 1) 16 cases of papillary carcinoma, 2) 16 cases suspicious for papillary carcinoma, and 3) 13 cases involving nonneoplastic lesions. Results: The follicular cells in the cytologically unequivocal papillary carcinoma diagnosis group expressed diffusely positive (+++) CK19, HBME-1, …
Comparison Of The Effect Of Contrast Medium, Air, And Ozone On Ischemia/Reperfusion Injury Due To Experimental Intussusception Model, Mi̇ne Fedakar Şenyücel, Ebru Şebnem Ayva, Mustafa Kemal Aslan, Özlem Boybeyi̇, Tutku Soyer, Nurkan Aksoy, Üçler Kisa, Ahmet Murat Çakmak
Comparison Of The Effect Of Contrast Medium, Air, And Ozone On Ischemia/Reperfusion Injury Due To Experimental Intussusception Model, Mi̇ne Fedakar Şenyücel, Ebru Şebnem Ayva, Mustafa Kemal Aslan, Özlem Boybeyi̇, Tutku Soyer, Nurkan Aksoy, Üçler Kisa, Ahmet Murat Çakmak
Turkish Journal of Medical Sciences
To compare effects of contrast medium, air, and ozone on ischemia/reperfusion injury due to intussusception. Materials and methods: Thirty Wistar rats were allocated into five groups (n = 6). In the control group (CG), 2 cm of colonic segment, 5 cm distal to ileocecal valve, was removed. Intussusception was performed at 5 cm distal to the ileocecal valve by pushing a proximal intestinal segment distally by stile in experimental groups. One hour later, in the sham-operated group (SG), manual reduction was performed. In the reduction groups, reduction of intussusception was performed by contrast medium (CMG, 1/1 diluted omnipaqueR, infusion rate …
Simultaneous Stenting Of The Ipsilateral External And Internal Carotid Arteries, Tahi̇r Durmaz, Engi̇n Bozkurt, Hüseyi̇n Ayhan, Ni̇hal Akar Bayram, Emi̇ne Bi̇len, Murat Akçay, Cenk Sari, Telat Keleş
Simultaneous Stenting Of The Ipsilateral External And Internal Carotid Arteries, Tahi̇r Durmaz, Engi̇n Bozkurt, Hüseyi̇n Ayhan, Ni̇hal Akar Bayram, Emi̇ne Bi̇len, Murat Akçay, Cenk Sari, Telat Keleş
Turkish Journal of Medical Sciences
Carotid artery diseases are diagnosed more frequently in practice due to increased mean life expectancy of the general population and the availability of imaging methods. Strong evidence coming from long term, randomized, large studies is required to support the idea that a carotid artery stent (CAS) may be an alternative to a carotid endarterectomy (CEA), which has been performed for long years with proven efficacy. Generally, no intervention (CEA or CAS) is performed in the stenosis of the external carotid artery (ECA) in the literature. In our case, we performed ipsilateral ECA and internal carotid artery stenting simultaneously.
Investigation Of Oxidative And Antioxidative Status In Patients With Diabetic Cataracts, Nagi̇han Uğurlu, Fatma Yülek, Şule Berk Ergun, Mehmet Doğan Aşik, Semra Işikoğlu, Emi̇ne Akçay
Investigation Of Oxidative And Antioxidative Status In Patients With Diabetic Cataracts, Nagi̇han Uğurlu, Fatma Yülek, Şule Berk Ergun, Mehmet Doğan Aşik, Semra Işikoğlu, Emi̇ne Akçay
Turkish Journal of Medical Sciences
To investigate the oxidative and antioxidative status in diabetic patients with cataracts and nondiabetic patients with cataracts as compared to controls. Materials and methods: There were 149 subjects included in the present study. Blood was collected from type 2 diabetic patients suffering from cataracts (diabetic cataract; n = 42), senile nondiabetic patients suffering from cataracts (nondiabetic cataracts; n = 60), and healthy subjects of a control group (n = 47). Serum levels of total oxidant status (TOS), total antioxidant status (TAS), total thiol levels (TTLs), and paraoxonase 1 (PON1) were investigated in the samples. Results: TTLs were significantly reduced in …
Comparison Of Sternal Intramedullary Bleeding Prevention Strategies In Cardiac Surgery, Murat Tavlaşoğlu, Ahmet Bariş Durukan, Mustafa Kürklüoğlu, Adem Güler, Zekeri̇ye Arslan, Mehmet Ali̇ Şahi̇n, Hasan Alper Gürbüz, Leyla Güler
Comparison Of Sternal Intramedullary Bleeding Prevention Strategies In Cardiac Surgery, Murat Tavlaşoğlu, Ahmet Bariş Durukan, Mustafa Kürklüoğlu, Adem Güler, Zekeri̇ye Arslan, Mehmet Ali̇ Şahi̇n, Hasan Alper Gürbüz, Leyla Güler
Turkish Journal of Medical Sciences
Sternal intramedullary bleeding is an important contributor to postcardiac surgery hemorrhage. The aim of this study is to investigate the effects of bone wax, oxidized regenerated cellulose, and electrocoagulation on sternal intramedullary hemostatic control. Materials and methods: A total of 142 patients undergoing on-pump coronary bypass surgery were prospectively studied. The patients were randomized into 3 groups; bone wax concomitant with electrocauterization, oxidized regenerated cellulose concomitant with electrocauterization, and electrocauterization alone. The amount of postoperative hemorrhage was noted at the 1st, 2nd, 3rd, 6th, 12th and 24th hours. Rates of reexploration for hemorrhage and number of units of blood and …
Analysis Of Kal1, Fgfr1, Gpr54, And Nelf Copy Number Variations By Multiplex Ligation Dependent Probe Amplification In Male Patients With Idiopathic Hypogonadotropic Hypogonadism, Yalçin Başaran, Hi̇lmi̇ Umut Ünal, Şi̇nasi̇ Erol Bolu, Rahşan Ilikçi Sağkan, Mustafa Çakar, Abdullah Taşlipinar, Taner Özgürtaş, Uğur Haci̇ Muşabak
Analysis Of Kal1, Fgfr1, Gpr54, And Nelf Copy Number Variations By Multiplex Ligation Dependent Probe Amplification In Male Patients With Idiopathic Hypogonadotropic Hypogonadism, Yalçin Başaran, Hi̇lmi̇ Umut Ünal, Şi̇nasi̇ Erol Bolu, Rahşan Ilikçi Sağkan, Mustafa Çakar, Abdullah Taşlipinar, Taner Özgürtaş, Uğur Haci̇ Muşabak
Turkish Journal of Medical Sciences
Hypogonadotropic hypogonadism is a production failure of gonadal hormones due to a lack of gonadotropin secretion. Here, we aimed to determine the prevalence of genomic rearrangements in the KAL1, FGFR1, GPR54, and NELF genes in patients diagnosed with hypogonadotropic hypogonadism. Materials and methods: The study included 86 male patients with idiopathic hypogonadotropic hypogonadism (76 diagnosed with normosmic idiopathic hypogonadotropic hypogonadism and 10 with Kallmann syndrome). Additionally, 95 healthy controls were recruited to investigate rearrangements in the KAL1, FGFR1, GPR54, and NELF genes, using multiplex ligation dependent probe amplification. Results: From the 86 patients, 3 patients with Kallmann syndrome had heterozygous …
Does Renal Parenchymal Thickness Affect Bleeding In Percutaneous Nephrolithotomy?, Mehmet Murat Ri̇fai̇oğlu, Kadi̇r Önem, Hüseyi̇n Çeli̇k, Mürsel Davarci, Mehmet Çeti̇nkaya, Mehmet İnci̇, Ayli̇n Güneşli̇ Yeti̇şken, Fati̇h Rüştü Yalçinkaya
Does Renal Parenchymal Thickness Affect Bleeding In Percutaneous Nephrolithotomy?, Mehmet Murat Ri̇fai̇oğlu, Kadi̇r Önem, Hüseyi̇n Çeli̇k, Mürsel Davarci, Mehmet Çeti̇nkaya, Mehmet İnci̇, Ayli̇n Güneşli̇ Yeti̇şken, Fati̇h Rüştü Yalçinkaya
Turkish Journal of Medical Sciences
Blood loss is a major concern during percutaneous nephrolithotomy. The aim of this study was to evaluate the effect of access point parenchymal thickness on bleeding in percutaneous nephrolithotomy procedures. Materials and methods: In this study 85 patients who had undergone a percutaneous nephrolithotomy operation between February 2009 and July 2011 were reviewed retrospectively. All characteristics of the patients were investigated. The details of the operative procedure and the renal parenchymal thickness at the puncture site were also recorded. Blood loss was calculated during the peroperative and postoperative periods. Correlation and multivariate regression analysis were done to detect predictive factors …
Investigation Of The Frequency Of The Mutant Ccr5-Δ32 Allele Related To Hiv Resistance In Turkey, Gamze Karakaya, Fatma Azi̇ze Budak Yildiran, Şükran Çakir Arica
Investigation Of The Frequency Of The Mutant Ccr5-Δ32 Allele Related To Hiv Resistance In Turkey, Gamze Karakaya, Fatma Azi̇ze Budak Yildiran, Şükran Çakir Arica
Turkish Journal of Medical Sciences
To determine the frequency with which the CCR5-\Delta32 mutant allele caused resistance to HIV, which is main agent of AIDS in all geographic regions of Turkey. Materials and methods: Randomly selected human blood samples from 400 healthy individuals were collected. The polymerase chain reaction method was used to determine the CCR5-\Delta32 polymorphism and samples were screened using 2 primers. Results: The frequency of wild alleles was found to be 0.9738 and the frequency of mutant alleles was found to be 0.0262. The highest frequency of the CCR5-\Delta32 allele was found to be 0.0726 in the Central Anatolia region. The lowest …
Pre-Versus Postoperative Tramadol Instillation: Both Are Effective For Decreasing Pain And/Or Agitation In Pediatric Adenotonsillectomy, Gülçi̇n Aydin, Alparslan Apan, Emi̇ne Arzu Köse, Gökşen Öz
Pre-Versus Postoperative Tramadol Instillation: Both Are Effective For Decreasing Pain And/Or Agitation In Pediatric Adenotonsillectomy, Gülçi̇n Aydin, Alparslan Apan, Emi̇ne Arzu Köse, Gökşen Öz
Turkish Journal of Medical Sciences
The present study aimed to investigate the possible influence of nasopharyngeal preoperative or postoperative tramadol instillation on postoperative pain and agitation in pediatric patients undergoing adenoidectomy, with or without tonsillectomy and tube placement. Materials and methods: Ninety pediatric patients were included in the study. Induction of anesthesia was achieved with 2.5 mg kg^{-1} propofol and 0.6 mg kg^{-1} rocuronium bromide. To maintain the anesthesia, 2%-2.5% sevoflurane in an oxygen-N2O mixture (FiO_2 = 35%) was administered. In Group I (n = 30), 1 mg kg^{-1} tramadol was given 10 min before adenoidectomy, and in Group II (n = 30) it was …
Effect Of Melatonin On Contractile Activity In Intraurethrally Instilled E. Coli-Induced Acute Prostatitis Rat Model, Bakhtiyar Huseynov, Nadi̇re Eser, İbrahi̇m Ati̇lla Aridoğan, Şeyda Erdoğan, Yusuf Kenan Dağlioğlu, Hacer Si̇nem Büyüknacar, Fati̇h Köksal, Cemi̇l Göçmen
Effect Of Melatonin On Contractile Activity In Intraurethrally Instilled E. Coli-Induced Acute Prostatitis Rat Model, Bakhtiyar Huseynov, Nadi̇re Eser, İbrahi̇m Ati̇lla Aridoğan, Şeyda Erdoğan, Yusuf Kenan Dağlioğlu, Hacer Si̇nem Büyüknacar, Fati̇h Köksal, Cemi̇l Göçmen
Turkish Journal of Medical Sciences
To investigate whether prostatic inflammation affects the contractile responses of prostate tissue and then whether melatonin has any restorative effect on the contractile responses in a rat model of bacterial prostatitis at early stages. Materials and methods: We evaluated the nerve-evoked, adrenergic agonist-induced or cholinergic agonist-induced contractions of isolated prostate tissue at 24 and 72 h after intraurethrally instilled Escherichia coli-treatment. We also analyzed the histological changes in the prostate. Secondarily, we investigated the effect of melatonin pretreatment (7 days, 10 mg kg^{-1} day^{-1}) on the contractile responses and the histopathologic changes. Results: The degrees of acute inflammatory cell infiltration, …
Effect Of Mental Stress On Cardiovascular Function At Rest And After Ingestion Of Fructose Or Sucralose In Healthy, White European Males, Muhammad Memon, Ian Macdonald, Terence Bennett
Effect Of Mental Stress On Cardiovascular Function At Rest And After Ingestion Of Fructose Or Sucralose In Healthy, White European Males, Muhammad Memon, Ian Macdonald, Terence Bennett
Turkish Journal of Medical Sciences
Ingestion of fructose and mental arithmetic can increase blood pressure (BP); the present study assessed the effect of fructose ingestion on cardiovascular (CV) response to mental stress. Effects were compared with sucralose used as a control. Materials and methods: Ten healthy, white European males were studied twice. A Finometer recorded CV parameters, noninvasively, throughout the study period. After the 30-min baseline, a mental arithmetic task (MAT), a series of arithmetic questions displayed as PowerPoint slides, was presented. Subjects, while resting on a bed, answered 20 questions in 2 min; 15 min after MAT-1, volunteers consumed 500 mL of lemon-flavoured drink …
The Expression Of Cell Adhesion Molecules In Colorectal Cancer Tissue And Its Clinical Values, Dong Chen, Huiying Zhao, Feng Ye
The Expression Of Cell Adhesion Molecules In Colorectal Cancer Tissue And Its Clinical Values, Dong Chen, Huiying Zhao, Feng Ye
Turkish Journal of Medical Sciences
To investigate the role of cell adhesion molecules CD44v6 and CEA in the occurrence, development, and metastasis of colorectal cancer (CRC). Materials and methods: The expression of CD44v6 and CEA in 76 CRC tissues and 43 normal colon tissues was detected using an immunohistological technique. The relationship between the 2 molecules’ expression and their pathologic characteristics, especially for metastasis, was investigated. Furthermore, the relevance between the expression of CD44v6 and of CEA was also assessed. Results: Expression of CD44v6 and CEA protein in CRC tissues was higher than in paracarcinoma tissue and normal colorectal mucosa (both P < 0.001). Positive expression of CD44v6 in CRC was associated with lymph node metastasis, Dukes’ stage, and histological differentiation. Higher expression intensity of CEA in CRC was related to lymph node involvement, distant metastasis, and invasion depth. Combining analysis of CD44v6 and CEA can improve the sensitivity and specificity in evaluating the metastatic potential of CRC (P < 0.05). There was no relevance between the expression of CD44v6 and CEA in CRC (P > 0.05). Conclusion: CD44v6 …
Cisplatin-Induced Kidney Damage And The Protective Effect Of Bilberry (Vaccinium Myrtillus L.): An Experimental Study, Di̇lek Pandir, Özlem Kara
Cisplatin-Induced Kidney Damage And The Protective Effect Of Bilberry (Vaccinium Myrtillus L.): An Experimental Study, Di̇lek Pandir, Özlem Kara
Turkish Journal of Medical Sciences
Bilberry is a natural antioxidant and has been utilized as a free radical scavenger to reverse the toxic effects of oxidative stress. The aim of this study was to investigate the effect of bilberry on cisplatin-induced toxic effects in rat kidney. Materials and methods: Twenty-one female Wistar-albino rats were randomly divided into 3 groups: group I (control), one dose of saline solution; group II (cisplatin), single dose of 7.5 mg/kg of cisplatin; group III (cisplatin + bilberry), single dose of 7.5 mg/kg of cisplatin and 10 days of bilberry treatment applied as 200 mg/kg of bilberry. Malondialdehyde (MDA) levels and …