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Thromboelastographic Evaluation Of Hemostatic Functionin Dogs With Dilated Cardiomyopathy, Zeki̇ Yilmaz, Meri̇ç Kocatürk, Oya Eralp İnan, Pinar Levent Jan 2017

Thromboelastographic Evaluation Of Hemostatic Functionin Dogs With Dilated Cardiomyopathy, Zeki̇ Yilmaz, Meri̇ç Kocatürk, Oya Eralp İnan, Pinar Levent

Turkish Journal of Veterinary & Animal Sciences

This study aimed to evaluate the hemostatic function by thromboelastography (TEG) and determine if there was an association between the changes in hemostatic parameters and serum cardiac troponin I (cTnI) in dogs with dilated cardiomyopathy (DCM). DCM was diagnosed by echocardiography in 19 dogs. Ten healthy dogs were selected as controls. Myocardial injury was confirmed by increased serum cTnI levels. Coagulation was assessed by TEG evaluating clot kinetics (reaction time [R] and kinetic time [K]), clot strengthening (alpha [α] angle and G value), platelet function (maximum amplitude [MA] and coagulation-index [CI]), clot stability (LY30, the percentage of lysis 30 min …


Metabolic Indicators For Early Pregnancy In Zebu And Crossbreddairy Cows Reared In A Subtropical Climate, Muzamil Abdulah, Tushar Kumar Mohanty, Mukesh Bhakat, Arumugam Kumaresan, Tapas Kumar Patbandha, Ambadas Rakhamaji Madkar, Ashok Kumar Mohanty Jan 2017

Metabolic Indicators For Early Pregnancy In Zebu And Crossbreddairy Cows Reared In A Subtropical Climate, Muzamil Abdulah, Tushar Kumar Mohanty, Mukesh Bhakat, Arumugam Kumaresan, Tapas Kumar Patbandha, Ambadas Rakhamaji Madkar, Ashok Kumar Mohanty

Turkish Journal of Veterinary & Animal Sciences

To identify metabolic indicators in blood and urine for early pregnancy in dairy cows (32 crossbred and 12 purebred zebu cows), blood and urine samples were collected on days 0, 15, 20, 24, and 30 postbreeding. The plasma progesterone (P4) concentration was significantly (P < 0.05) higher in pregnant cows than in nonpregnant cows after day 15. The plasma blood urea nitrogen (BUN) concentration remained significantly (P < 0.05) higher in pregnant cows on day 15. The plasma concentrations of cholesterol, glucose, protein, and nonesterified fatty acid (NEFA) did not differ between pregnant and nonpregnant cows. The urine protein concentration was significantly higher (P < 0.05) in pregnant zebu cows compared to nonpregnant zebu cows. Plasma P4 was significantly (P < 0.001) and positively associated with urine glucose levels in nonpregnant crossbred cows. In nonpregnant zebu cows, the correlation between P4 was positive (P < 0.05) with plasma cholesterol, glucose, urine glucose, and protein. In pregnant zebu cows, P4 was negatively associated with plasma BUN and positively (P < 0.05) associated with both plasma and urine glucose levels. Thus, urinary proteins can be used as a noninvasive tool for early nonpregnancy confirmation in cows with very high accuracy at around 24 days after artificial insemination.


Detection Of High Levels Of Somatic Cells In Milk On Farms Equippedwith An Automatic Milking System By Decision Trees Technique, Beata Sitkowska, Dariusz Piwczynski, Joanna Aerts, Magdalena Kolenda, Serkan Özkaya Jan 2017

Detection Of High Levels Of Somatic Cells In Milk On Farms Equippedwith An Automatic Milking System By Decision Trees Technique, Beata Sitkowska, Dariusz Piwczynski, Joanna Aerts, Magdalena Kolenda, Serkan Özkaya

Turkish Journal of Veterinary & Animal Sciences

The purpose of the study was to use decision trees to predict increased levels of somatic cells in cow's milk. The material for the study comprised data collected in 2012-2014 from five farms in Poland equipped with an automatic milking system. Data on 803 Polish Holstein-Friesian cows were collected. In order to predict somatic cell count data mining techniques were used to build a graphical model of a decision tree. This study found that the most important factors to anticipate an elevated somatic cell count in cow's milk are milk conductivity, lactation stage, and lactation (primiparous and multiparous cow groups), …


Slaughter And Carcass Characteristics Of Herik Male Lambs Raised Under A Finishing System, Mustafa Uğurlu, Bülent Teke, Fi̇li̇z Akdağ, Mustafa Salman, Bülent Eki̇z, İsmai̇l Kaya Jan 2017

Slaughter And Carcass Characteristics Of Herik Male Lambs Raised Under A Finishing System, Mustafa Uğurlu, Bülent Teke, Fi̇li̇z Akdağ, Mustafa Salman, Bülent Eki̇z, İsmai̇l Kaya

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to determine the slaughter and carcass characteristics of Herik lambs finished under intensive husbandry conditions. Twenty single male lambs, ten of which had long, semifat tails and ten of which had short, round, and fat tails, all with an average live weight of 20 kg, were used in the study. Concentrate feed and fresh water were given ad libitum and alfalfa hay as forage was given in the amount of 300 g/lamb per day. The lambs were slaughtered when they reached a final weight of 42 kg. The average hot and cold dressing percentages, …


Effective Use Of Probiotic-Glyconutrient Combination As An Adjuvant To Antibiotic Therapy For Diarrhea In Rearing Dairy Calves, Gilberto Lopez Valencia, Octavio Zapata-Ramirez, Lilia Núñez-González, Victor Núñez-Benítez, Heriberto Landeros- López, Maria Lopez-Soto, Alberto Barreras Serrano, Victor Gonzalez-Vizcarra, Alfredo Estrada-Angulo, Richard Zinn, Alejandro Plascencia Jan 2017

Effective Use Of Probiotic-Glyconutrient Combination As An Adjuvant To Antibiotic Therapy For Diarrhea In Rearing Dairy Calves, Gilberto Lopez Valencia, Octavio Zapata-Ramirez, Lilia Núñez-González, Victor Núñez-Benítez, Heriberto Landeros- López, Maria Lopez-Soto, Alberto Barreras Serrano, Victor Gonzalez-Vizcarra, Alfredo Estrada-Angulo, Richard Zinn, Alejandro Plascencia

Turkish Journal of Veterinary & Animal Sciences

Thirty Holstein calves presented with infectious diarrhea during the second week following birth were utilized to evaluate the effects of a standardized product containing a combination of probiotics, ß-glucans, and glyconutrients (GLY) in support of antibiotic therapy during the early rearing phase (day 7 to day 45 following birth). Treatments were 1) antibiotic therapy (trimethoprim and sulfas; ANTIB), and 2) ANTIB plus 5 g/calf per day GLY. Treatments did not affect diarrhea duration, averaging 16.7 days. However, GLY support decreased (P < 0.05) the mortality rate and increased (P < 0.05) live weight gain. Increased weight gain was attributable to enhanced (P < 0.05) consumption of calf starter. Supplemental GLY increased (P < 0.05) serum glucose and lowered (P < 0.05) serum urea nitrogen, nonesterified fatty acids, and cortisol concentration. We conclude that daily provision of 5 g of a standardized product containing probiotics, ß-glucans, and glyconutrients to diarrheic calves under antibiotic therapy will promote health and enhance early growth performance.


Evaluation Of Major And Minor Lower Extremity Amputation In Diabetic Foot Patients, Firat Ozan, Kaan Gürbüz, İlhami̇ Çeli̇k, Zehra Beştepe Dursun, Erdal Uzun Jan 2017

Evaluation Of Major And Minor Lower Extremity Amputation In Diabetic Foot Patients, Firat Ozan, Kaan Gürbüz, İlhami̇ Çeli̇k, Zehra Beştepe Dursun, Erdal Uzun

Turkish Journal of Medical Sciences

Background/aim: We evaluated the existing risk factors with clinical results in patients who underwent major and minor amputation of the lower extremity as a result of diabetic foot ulcers (DFUs). Materials and methods: We retrospectively studied 107 patients who had undergone lower extremity amputation. The patients were divided into minor (Group 1, n = 75) and major (Group 2, n = 32) amputation groups. On clinical evaluation, the type of surgery performed, smoking history, comorbidities, duration of diabetes mellitus (DM) diagnosis, duration of DFU presence, peripheral neuropathy, peripheral arterial disease, results of deep tissue culture, length of hospitalization, and blood …


Decreased Oxidative Stress May Contribute To The Disease Process In Placenta Accreta, Efser Öztaş, Si̇bel Özler, Merve Ergi̇n, Özcan Erel, Başak Güler, Ali̇ Turhan Çağlar, Aykan Yücel, Di̇lek Uygur, Ahmet Nuri̇ Danişman Jan 2017

Decreased Oxidative Stress May Contribute To The Disease Process In Placenta Accreta, Efser Öztaş, Si̇bel Özler, Merve Ergi̇n, Özcan Erel, Başak Güler, Ali̇ Turhan Çağlar, Aykan Yücel, Di̇lek Uygur, Ahmet Nuri̇ Danişman

Turkish Journal of Medical Sciences

Background/aim: The main aim of this study was to investigate serum total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), and arylesterase levels in pregnant women with placenta accreta and to compare those with age-matched healthy pregnant women. Materials and methods: A total of 27 pregnant women who had clinically and pathologically proven placenta accreta and 30 age- and BMI- matched healthy pregnant women were enrolled in this case control study. Maternal serum TOS, TAS, OSI, and arylesterase levels were evaluated using logistic regression analysis to determine if there was an association with abnormal placental invasion or …


Comparison Of Microscopy, Elisa, And Real-Time Pcr For Detectionof Giardia Intestinalis In Human Stool Specimens, Yunus Emre Beyhan, Zeynep Taş Cengi̇z Jan 2017

Comparison Of Microscopy, Elisa, And Real-Time Pcr For Detectionof Giardia Intestinalis In Human Stool Specimens, Yunus Emre Beyhan, Zeynep Taş Cengi̇z

Turkish Journal of Medical Sciences

Background/aim: This study included patients who had digestive system complaints between August 2015 and October 2015. The research was designed to compare conventional microscopy with an antigen detection ELISA kit and the TaqMan-based real-time PCR (RT-PCR) technique for detection of Giardia intestinalis in human stool specimens. Materials and methods: Samples were concentrated by formalin-ether sedimentation technique and microscopic examinations were carried out on wet mount slides. A commercially available ELISA kit (Giardia CELISA, Cellabs, Brookvale, Australia) was used for immunoassay. DNA was extracted from fecal samples of about 200 mg using the QIAamp Fast DNA Stool Mini Kit (QIAGEN, Hilden, …


Pathological And Immunohistochemical Evaluation Of Skin And Teat Papillomas In Cattle, Enver Beytut Jan 2017

Pathological And Immunohistochemical Evaluation Of Skin And Teat Papillomas In Cattle, Enver Beytut

Turkish Journal of Veterinary & Animal Sciences

Bovine skin and teat papillomas were examined for immunohistochemical expression of bovine papillomavirus (BPV), proliferating antigens (PCNA, Ki-67), CD3+ T lymphocytes, and some of the type III intermediate filaments. Papillomas showed epidermal hyperplasia, koilocytes, and hyperkeratosis with prominent dermal connective tissue. Immunohistochemistry found the presence of BPV antigens in the nuclei of granulosa cells. PCNA and Ki-67 revealed positive nuclear staining in the dermis and epidermis. Perivascular cuffing in the dermis predominantly consisted of CD3+ T cells. Immunoreaction to vimentin was strong in the connective tissue of the dermis. $\alpha$SMA positivity was mainly in the media of vessels. Smooth muscle …


The Comparison Of The Effects Of Intraarticular Injections Of Bovine Amnioticfluid And Hyaluronic Acid On Cartilage Tissue In An Experimental Osteoarthriticrabbit Model: Histopathological And Immunohistochemical Results, Murat Tanrisever, Hati̇ce Eröksüz, Sai̇t Bulut Jan 2017

The Comparison Of The Effects Of Intraarticular Injections Of Bovine Amnioticfluid And Hyaluronic Acid On Cartilage Tissue In An Experimental Osteoarthriticrabbit Model: Histopathological And Immunohistochemical Results, Murat Tanrisever, Hati̇ce Eröksüz, Sai̇t Bulut

Turkish Journal of Veterinary & Animal Sciences

In this experimental study, effects of bovine amniotic fluid and hyaluronic acid were compared on an osteoarthritic model induced in rabbit stifle joints. The study was performed on 21 rabbits undergoing anterior cruciate ligament transaction for establishing osteoarthritis. Four weeks later, the rabbits were divided into 3 equal groups of 7 animals each. The first group of rabbits received intraarticular injection of 0.5 mL of bovine amniotic fluid (BAF) three times at 1-week intervals. The second group of rabbits received intraarticular injection of 0.5 mL of hyaluronic acid (HA) three times at 1-week intervals. The third group of rabbits served …


Development And Evaluation Of Time-Temperature Integrator Formonitoring High Temperature Thawing Of Frozen Buffalo Meat, Vishnuraj Mangalathu Rajan, Kandeepan Gurunathan, Vivek Shukla Jan 2017

Development And Evaluation Of Time-Temperature Integrator Formonitoring High Temperature Thawing Of Frozen Buffalo Meat, Vishnuraj Mangalathu Rajan, Kandeepan Gurunathan, Vivek Shukla

Turkish Journal of Veterinary & Animal Sciences

Research was undertaken to develop an enzyme-substrate-based time-temperature integrator (TTI) for monitoring higher temperature thawing of frozen buffalo meat. Alpha-amylase and iodine-starch complex were standardized for enzyme-substrate combinations and process optimization and packed in 2 × 2 cm LDPE bags. The meat samples were packed in polystyrene trays with cling film overwrap and frozen at -18 ± 1 °C. Each sample had a sticker-type TTI attached to the surface of the package. The frozen samples were subjected to temperature abuse at 25 ± 1 °C and 37 ± 1 °C, keeping a control at 4 ± 1 °C. On higher …


Chromosomal Findings And Sequence Analysis Of Target Exons Of Calcium-Sensingreceptor (Casr) Gene In Patients With Sagliker Syndrome, Erdal Tunç, Osman Demi̇rhan, Yahya Sağliker, İsmai̇l Yildiz, Nuray Paylar, Ali̇ İrfan Güzel Jan 2017

Chromosomal Findings And Sequence Analysis Of Target Exons Of Calcium-Sensingreceptor (Casr) Gene In Patients With Sagliker Syndrome, Erdal Tunç, Osman Demi̇rhan, Yahya Sağliker, İsmai̇l Yildiz, Nuray Paylar, Ali̇ İrfan Güzel

Turkish Journal of Medical Sciences

Background/aim: Sagliker syndrome (SS) develops as a continuation of chronic kidney disease and secondary hyperparathyroidism conditions. It was thought that there are some genetic predisposition factors leading to SS. The calcium-sensing receptor (CaSR) is essential for calcium homeostasis in the body. We aimed to examine SS patients for chromosome aberrations (CAs) and CaSR gene abnormalities in exons 2 and 3. Materials and methods: Twenty-three patients and 23 control subjects were admitted to Balcalı Hospital of the Medical Faculty of Çukurova University in Turkey between 2009 and 2011. Chromosomal analysis was performed according to standard cytogenetic methods. Full sequencing of exons …


Pooled Analysis Of 899 Nosocomial Meningitis Episodes From Turkey, Oğuz Reşat Si̇pahi̇, Arzu Nazli Zeka, Meltem Taşbakan, Hüsnü Pullukçu, Bi̇lgi̇n Arda, Tansu Yamazhan, Hi̇lal Si̇pahi̇, Sercan Ulusoy Jan 2017

Pooled Analysis Of 899 Nosocomial Meningitis Episodes From Turkey, Oğuz Reşat Si̇pahi̇, Arzu Nazli Zeka, Meltem Taşbakan, Hüsnü Pullukçu, Bi̇lgi̇n Arda, Tansu Yamazhan, Hi̇lal Si̇pahi̇, Sercan Ulusoy

Turkish Journal of Medical Sciences

Background/aim: Healthcare-associated meningitis (HCAM) is a relatively rare entity with significant morbidity and mortality. The aim of this study was to systematically review the Turkish medical literature for acute nosocomial meningitis. Materials and methods: One national (ULAKBİM) and two international (www.scopus.com and www.pubmed.com) databases were searched. In addition, abstracts of four national congresses held between 2004 and 2013 were searched for reports for HCAM meningitis. Results: Data for 899 HCAM meningitis episodes were obtained from 24 reports. In terms of clinical findings, 177 of 216 (81.9%) had fever (>38 °C), 55 of 64 (85.9%) had high CRP levels, 105 …


Potential Drug-Drug Interactions Among Prescriptionsfor Elderly Patients In Primary Health Care, Zafer Gören, Mahluga J. Demirkapu, Gökçe Akpinar Acet, Sanda Çali, Medine Gülçebi̇ İdri̇z Oğlu Jan 2017

Potential Drug-Drug Interactions Among Prescriptionsfor Elderly Patients In Primary Health Care, Zafer Gören, Mahluga J. Demirkapu, Gökçe Akpinar Acet, Sanda Çali, Medine Gülçebi̇ İdri̇z Oğlu

Turkish Journal of Medical Sciences

Background/aim: Elderly patients are at high risk from drug-drug interactions (DDIs). This study evaluates the potential DDIs in Turkish elderly patients at a primary health care outpatient clinic. Materials and methods: Online database systems were used to examine DDIs on the prescriptions of patients (n = 1206). The clinical severity of DDIs was classified by the Lexi-Interact Online database. Results: Of the 5059 prescriptions, 33% were found to have DDIs. We detected 29 (0.9%) A, 380 (11.8%) B, 2494 (77.7%) C, 289 (9%) D, and 18 (0.6%) X risk rating category DDIs among the prescriptions. Prescriptions of female patients and …


Intravitreal Prn Ranibizumab Treatment For Macular Edemadue To Branch Retinal Vein Occlusion, Hasan Basri̇ Çakmak, Mücella Arikan Yorgun, Yasi̇n Toklu, Melek Mutlu Jan 2017

Intravitreal Prn Ranibizumab Treatment For Macular Edemadue To Branch Retinal Vein Occlusion, Hasan Basri̇ Çakmak, Mücella Arikan Yorgun, Yasi̇n Toklu, Melek Mutlu

Turkish Journal of Medical Sciences

Background/aim: To evaluate the effect of intravitreal pro re nata (PRN) ranibizumab treatment from the start on the best-corrected visual acuity (BCVA) and the central retinal thickness (CRT) in macular edema (ME) due to branch retinal vein occlusion (BRVO). Materials and methods: Patients with ME secondary to BRVO, who were treated on a PRN basis after a single intravitreal ranibizumab injection, were retrospectively evaluated. The main outcome measures were changes in BCVA and CRT as measured by optical coherence tomography. Results: The number of injections over 6 months was 2.43 ± 1.16. The mean BCVA of the patients was 0.84 …


Determination Of The Ideal Sampling Technique To Reduce Repeated Procedures:A Comparative Study Including 393 Fine-Needle Aspirations For Thyroid Nodules, Fati̇h Uzunkaya, Ahmet Özden Jan 2017

Determination Of The Ideal Sampling Technique To Reduce Repeated Procedures:A Comparative Study Including 393 Fine-Needle Aspirations For Thyroid Nodules, Fati̇h Uzunkaya, Ahmet Özden

Turkish Journal of Medical Sciences

Background/aim: Fine-needle aspiration biopsy is an established method for the evaluation of thyroid nodules, but it has not been standardized worldwide yet. Adequacy of the aspirations is affected by several factors. The aim of this study is to determine the main factors affecting the adequacy and to suggest a procedural technique expected to reduce repeated procedures. Materials and methods: A total of 393 aspiration procedures performed using either 22-gauge or 27-gauge needles were included in the study. The samplings were classified as inadequate or adequate according to the cytopathological reports, and results were compared. Results: The rate of adequate samplings …


Prevalence And Associated Factors Of Thrombocytopenia Among Human Immunodeficiency Virus-Infected Patients At A Tertiary Care Hospital In İzmir, Turkey, Can Hüseyi̇n Heki̇moğlu, Fi̇gen Kaptan, İlknur Vardar, Serap Ural, Nesri̇n Türker, Bahar Örmen, Nurbanu Sezak, Si̇bel El Jan 2017

Prevalence And Associated Factors Of Thrombocytopenia Among Human Immunodeficiency Virus-Infected Patients At A Tertiary Care Hospital In İzmir, Turkey, Can Hüseyi̇n Heki̇moğlu, Fi̇gen Kaptan, İlknur Vardar, Serap Ural, Nesri̇n Türker, Bahar Örmen, Nurbanu Sezak, Si̇bel El

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to determine the prevalence and associated factors of thrombocytopenia in human immunodeficiency virus (HIV)-infected patients. Materials and methods: A cross-sectional study was conducted in a tertiary care hospital in İzmir, Turkey. All HIV-infected patients admitted to the Department of Infectious Diseases and Clinical Microbiology between 2006 and 2011 were recruited. Patients with thrombocytopenia at any time point were defined as the case group and the remaining patients were defined as the control group. Results: The frequency of thrombocytopenia was 35.8%. Thrombocytopenia was more frequent in patients with acquired immune deficiency syndrome (AIDS) than …


Relation Of Unsupported And Unsupervised Exercise With Anthropometric And Biochemical Indices Among Type 2 Diabetic Patients, Prince Chikwere, Kwabena Nsiah, Marina Tandoh Jan 2017

Relation Of Unsupported And Unsupervised Exercise With Anthropometric And Biochemical Indices Among Type 2 Diabetic Patients, Prince Chikwere, Kwabena Nsiah, Marina Tandoh

Turkish Journal of Medical Sciences

Background/aim: Type 2 diabetes is a lifestyle-related condition. Lifestyle modification in the management of type 2 diabetes incorporates exercise. The aim of this study was to find out how unsupported and unsupervised exercise relates to anthropometric indices and biochemical indices in type 2 diabetes patients. Materials and methods: In the cross-sectional study, a structured questionnaire was used to access data on the exercise history of patients. Subjects were classified according to exercise intensity. The dietary intake of patients was obtained by 24-h recall. Standard measurements were taken of waist circumference and blood pressure. Blood samples were also collected to measure …


Abdominal Actinomycosis In The Last 10 Years And Risk Factors For Appendiceal Actinomycosis: Review Of The Literature, Marta Lisa-Gracia, Berta Martín-Rivas, Marcos Pajaron-Guerrero, Ana Arnaiz-García Jan 2017

Abdominal Actinomycosis In The Last 10 Years And Risk Factors For Appendiceal Actinomycosis: Review Of The Literature, Marta Lisa-Gracia, Berta Martín-Rivas, Marcos Pajaron-Guerrero, Ana Arnaiz-García

Turkish Journal of Medical Sciences

Background/aim: Actinomycosis is a granulomatous disease caused by filamentous, gram-positive, anaerobic bacteria. Actinomycetes are commensal inhabitants of the oral cavity and intestinal tract but acquire pathogenicity through invasion of breached or necrotic tissue. In abdominal actinomycosis (AA), the appendix and ileocecal region are usually involved. The aim of this study was to characterize patients diagnosed with AA and to establish the risk factors for appendiceal actinomycosis, including a short review of the literature. Materials and methods: We conducted a prospective cohort study of all patients diagnosed with AA in the University Hospital Marques de Valdecilla (Santander-Cantabria) from January 2003 to …


Nitric Oxide In Cerebrospinal Fluid Of Central Nervous System Tuberculosis: Correlations With Culture, Antibody Response, And Cell Count, Kavitha Kumar, Prashant Giribhattanavar, Shripad Patil Jan 2017

Nitric Oxide In Cerebrospinal Fluid Of Central Nervous System Tuberculosis: Correlations With Culture, Antibody Response, And Cell Count, Kavitha Kumar, Prashant Giribhattanavar, Shripad Patil

Turkish Journal of Medical Sciences

Background/aim: The role of nitric oxide (NO) has been established in infection over the years. NO functions by inhibiting the growth of intracellular pathogens. The present study was undertaken to ascertain the role of NO in central nervous system (CNS) infection by Mycobacterium tuberculosis. Materials and methods: A total of 781 chronic meningitis cerebrospinal fluid (CSF) samples suspected of CNS tuberculosis (TB) were categorized based on M. tuberculosis culture positivity, anti-TB antibody response, and CSF cell count and were analyzed for NO. Results: We found that NO levels were positive in 10.88% of the CSF samples. Positivity for NO was …


Endometriosis-Associated Changes In Serum Levels Of Interferons And Chemokines, Andrei Mihai Malutan, Tudor Drugan, Razvan Ciortea, Carmen Bucuri, Maria Patricia Rada, Dan Mihu Jan 2017

Endometriosis-Associated Changes In Serum Levels Of Interferons And Chemokines, Andrei Mihai Malutan, Tudor Drugan, Razvan Ciortea, Carmen Bucuri, Maria Patricia Rada, Dan Mihu

Turkish Journal of Medical Sciences

Background/aim: The aim of the study was to evaluate the serum concentration of main chemokines and interferons in patients with diagnosed endometriosis. Materials and methods: A total of 160 women were divided in two study groups (group 1 - endometriosis; group 2 - healthy women). Serum levels of IFN-α, IFN-γ, MCP-1, MIP-1α, MIP-1β, RANTES, eotaxin, IL-8, MIG, IP-10, and IL-17A were measured with Human Multiplex Cytokine Panels. Results. Serum levels of IFN-γ, MCP-1, and IL-8 were significantly higher (mean 14.03, 57.24, and 534.24, respectively, compared to 0.58, 20.51, and 259.82, respectively), and serum levels of IP-10 and eotaxin were significantly …


Qf-Pcr In Invasive Prenatal Diagnosis: A Single-Center Experience In Turkey, Özge Özer Kaya, Altuğ Koç, Taha Reşi̇d Özdemi̇r, Özgür Kirbiyik, Berk Özyilmaz, Mehmet Özeren, Deni̇z Can Özteki̇n, Cüneyt Eftal Taner, Yaşar Beki̇r Kutbay Jan 2017

Qf-Pcr In Invasive Prenatal Diagnosis: A Single-Center Experience In Turkey, Özge Özer Kaya, Altuğ Koç, Taha Reşi̇d Özdemi̇r, Özgür Kirbiyik, Berk Özyilmaz, Mehmet Özeren, Deni̇z Can Özteki̇n, Cüneyt Eftal Taner, Yaşar Beki̇r Kutbay

Turkish Journal of Medical Sciences

Background/aim: QF-PCR has been used for more than 20 years. It is based on investigation of polymorphic short tandem repeats (STRs) and is widely used for prenatal rapid aneuploidy detection. Materials and methods: We report retrospectively our prenatal diagnosis results between January 2012 and May 2014 in Tepecik Training and Research Hospital Genetic Diagnostic Center. Prenatal diagnosis was recommended in 6800 high-risk pregnancies and 2883 patients agreed to invasive diagnosis. Chromosome analysis and QF-PCR were performed in all patients. Results: Normal results were reported in 2711 cases by fetal karyotyping and in 2706 cases by QF-PCR. Anomaly detection rates were …


Using Fuzzy Logic For Diagnosis And Classification Of Spasticity, Veysel Alcan, Mehmet Rahmi̇ Canal, Murat Zi̇nnuroğlu Jan 2017

Using Fuzzy Logic For Diagnosis And Classification Of Spasticity, Veysel Alcan, Mehmet Rahmi̇ Canal, Murat Zi̇nnuroğlu

Turkish Journal of Medical Sciences

Background/aim: Spasticity is generally defined as a sensory-motor control disorder. However, there is no pathophysiological mechanism or appropriate measurement and evaluation standards that can explain all aspects of a possible spasticity occurrence. The objective of this study is to develop a fuzzy logic classifier (FLC) diagnosis system, in which a quantitative evaluation is performed by surface electromyography (EMG), and investigate underlying pathophysiological mechanisms of spasticity. Materials and methods: Surface EMG signals recorded from the tibialis anterior and medial gastrocnemius muscles of hemiplegic patients with spasticity and a healthy control group were analyzed in standing, resting, dorsal flexion, and plantar flexion …


Comparison Of Response To Treatment Of Unilateral And Bilateral Varicocelectomy, Ercan Öğreden, Ural Oğuz, Abdullah Çirakoğlu, Erhan Demi̇relli̇, Erdal Benli̇, Orhan Yalçin Jan 2017

Comparison Of Response To Treatment Of Unilateral And Bilateral Varicocelectomy, Ercan Öğreden, Ural Oğuz, Abdullah Çirakoğlu, Erhan Demi̇relli̇, Erdal Benli̇, Orhan Yalçin

Turkish Journal of Medical Sciences

Background/aim: We aimed to compare the results of unilateral and bilateral varicocele surgery. Materials and methods: In two referral hospitals, the data of 180 patients who were treated with unilateral and bilateral microscopic varicocelectomy were retrospectively analyzed. Sperm parameters and spontaneous pregnancy rates were compared in patients who underwent bilateral and unilateral microscopic varicocelectomy. Results: The mean age was 29.6 (17-46) years. While 82 patients underwent unilateral varicocelectomy (Group I), 98 patients underwent bilaterally varicocelectomy (Group II). Forty (48.8%) spontaneous pregnancies occurred in Group I and 59 (60.2%) in Group II. When we analyzed sperm parameters, the rate of increase …


The Prevalence Of Coronary Artery Anomalies With Coronary Computed Tomography, Hakki Yeşi̇lyurt, Uğur Aksu, Kamuran Kalkan, Seli̇m Topcu, Enbi̇ya Aksakal, İbrahi̇m Hali̇l Tanboğa, Recep Sade, Fati̇h Rifat Ulusoy, Abdulmeci̇t Kantarci Jan 2017

The Prevalence Of Coronary Artery Anomalies With Coronary Computed Tomography, Hakki Yeşi̇lyurt, Uğur Aksu, Kamuran Kalkan, Seli̇m Topcu, Enbi̇ya Aksakal, İbrahi̇m Hali̇l Tanboğa, Recep Sade, Fati̇h Rifat Ulusoy, Abdulmeci̇t Kantarci

Turkish Journal of Medical Sciences

Background/aim: In this study, the aim is to investigate the prevalence of various coronary artery anomalies (CAAs), evaluated by 256-detector row coronary computed tomography (CCT), within the Turkish population. Materials and methods: We included 2973 patients who had received CCT. The high take-off right coronary artery (RCA) and left coronary artery (LCA), the RCA arising from the left sinus (LS), the LCA arising from the right sinus (RS), the circumflex artery (CX) arising from the RS, the single coronary ostium originating from the RS, the CX arising from the RCA, and the RCA arising from the pulmonary artery were evaluated. …


Retrospective Analysis Of Primary Gastric Diffuse Largeb-Cell Lymphoma: A Single Center Study From Turkey, Nur Soyer, Asu Fergün Yilmaz, Nazan Özsan, Fahri̇ Şahi̇n, Güray Saydam, Murat Tombuloğlu, Mi̇ne Heki̇mgi̇l, Fi̇li̇z Vural Jan 2017

Retrospective Analysis Of Primary Gastric Diffuse Largeb-Cell Lymphoma: A Single Center Study From Turkey, Nur Soyer, Asu Fergün Yilmaz, Nazan Özsan, Fahri̇ Şahi̇n, Güray Saydam, Murat Tombuloğlu, Mi̇ne Heki̇mgi̇l, Fi̇li̇z Vural

Turkish Journal of Medical Sciences

Background/aim: Diffuse large B-cell primary gastric lymphomas (DLBC-PGLs) are treated with different therapies. Their optimal treatment is not well documented. Materials and methods: We retrospectively analyzed the data of 51 patients diagnosed with DLBC-PGL in the previous 10 years. All patients were treated with R-CHOP as first line. Radiotherapy was added to chemotherapy in 8 patients. Surgery was performed in 5 patients. Results: The median follow-up time of the 51 patients was 45.5 (range 5-144) months and the complete response (CR) rate was 90.2%. CR was achieved in 34 (89.4%) of 38 patients treated with single chemotherapy, in all (100%) …


Evaluation Of Dental Technician's Pneumoconiosis Using Chest X-Rayand Hrct: Correlation Between Radiological And Functional Findings, Recai̇ Ergün, Di̇lek Ergün, Ender Evci̇k, Begüm Ergan Jan 2017

Evaluation Of Dental Technician's Pneumoconiosis Using Chest X-Rayand Hrct: Correlation Between Radiological And Functional Findings, Recai̇ Ergün, Di̇lek Ergün, Ender Evci̇k, Begüm Ergan

Turkish Journal of Medical Sciences

Background/aim: This study aimed to compare high-resolution computed tomography (HRCT) findings with those of chest X-ray (CXR) and to evaluate the relationship of pulmonary function test (PFT) parameters with HRCT and CXR findings in cases of dental technician's pneumoconiosis. Materials and methods: CXR, PFT, and HRCT data of 89 dental technicians who were diagnosed with pneumoconiosis were retrospectively evaluated. Results: The cases of 24 dental technicians (27%) classified as normal (Category 0) based on CXR were evaluated as Category 1 according to HRCT. There was an inverse correlation of PFT parameters with nodular profusion score in CXR and all HRCT …


A Descriptive Study Of Adherence To Lifestyle Modificationfactors Among Hypertensive Patients, Fadwa Alhalaiqa, Ahmad Al-Nawafleh, Abdul-Monim Batiha, Rami Masa'deh, Aida Abd Al-Razek Jan 2017

A Descriptive Study Of Adherence To Lifestyle Modificationfactors Among Hypertensive Patients, Fadwa Alhalaiqa, Ahmad Al-Nawafleh, Abdul-Monim Batiha, Rami Masa'deh, Aida Abd Al-Razek

Turkish Journal of Medical Sciences

Background/aim: Healthy life style recommendations (e.g., physical activity, healthy diet, and decreased cholesterol levels) play an important role in controlling blood pressure (BP). This study aimed to assess lifestyle modification factors among patients diagnosed with hypertension. Materials and methods: A descriptive-survey design was used. Data were collected using four questionnaires; one was the Beliefs about Medication questionnaire (BMQ) and the rest were developed to collect data about demographic and clinical characteristics and lifestyle modification factors. Results: In total 312 questionnaires were completed. The results revealed that our participants did not follow the healthy lifestyle recommendations; for example, the mean blood …


Can Ischemia-Modified Albumin Be Used To Differentiate Between Generalized Seizures And Pseudoseizures?, Tülay Kamaşak, Süleyman Türedi̇, Hepsen Mi̇ne Seri̇n, Ahmet Menteşe, Abdülkadi̇r Gündüz, Ahmet Alver, Ali̇ Cansu Jan 2017

Can Ischemia-Modified Albumin Be Used To Differentiate Between Generalized Seizures And Pseudoseizures?, Tülay Kamaşak, Süleyman Türedi̇, Hepsen Mi̇ne Seri̇n, Ahmet Menteşe, Abdülkadi̇r Gündüz, Ahmet Alver, Ali̇ Cansu

Turkish Journal of Medical Sciences

Background/aim: In recent years ischemia-modified albumin (IMA) has been suggested as a marker that can be used in differentiating nonconvulsive conditions from epilepsy. The purpose of this study was to investigate changes in IMA levels caused by generalized clonic tonic (GTC) seizures. Materials and methods: A total of 114 children presenting to the Karadeniz Technical Pediatric Emergency Polyclinic with GTC seizures were included in the study. Sixteen cases meeting the inclusion criteria were included in the study and sixteen healthy children were enrolled as the control group. The patients' IMA, albumin, and IMA/albumin values at hours 0 and 1 following …


Pentoxifylline Attenuates Mucosal Damage In An Experimental Model Of Rat Colitis By Modulating Tissue Biomarkers Of Inflammation, Oxidative Stress, And Fibrosis, Eylem Karatay, Özlem Gül Utku, Harun Erdal, Mehmet Arhan, İbrahi̇m Koral Önal, Mehmet İbi̇ş, Özgür Eki̇nci̇, Canan Yilmaz Demi̇rtaş, Gi̇yaseddi̇n Şükrü Dumlu Jan 2017

Pentoxifylline Attenuates Mucosal Damage In An Experimental Model Of Rat Colitis By Modulating Tissue Biomarkers Of Inflammation, Oxidative Stress, And Fibrosis, Eylem Karatay, Özlem Gül Utku, Harun Erdal, Mehmet Arhan, İbrahi̇m Koral Önal, Mehmet İbi̇ş, Özgür Eki̇nci̇, Canan Yilmaz Demi̇rtaş, Gi̇yaseddi̇n Şükrü Dumlu

Turkish Journal of Medical Sciences

Background/aim: This study was designed to identify the effect of pentoxifylline on trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats. Materials and methods: Forty-two female Wistar rats were randomly divided into 7 groups: group A, TNBS + intraperitoneal (IP) pentoxifylline; group B, TNBS + IP saline; group C, TNBS + intrarectal (IR) pentoxifylline; group D, TNBS + IR saline; group E, IP pentoxifylline + TNBS; group F, IP saline + TNBS; group G, IR saline. Pentoxifylline was given daily for 3 days before or 6 days after the induction of colitis. Rats were killed after 6 days. Results: IP and IR …