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Is Body Mass Index A Risk Factor For Low Cerebral Oxygenation During Spinal Anesthesia In Women Undergoing Cesarean Section? A Preliminary Study, Gülçi̇n Aydin, Cemi̇le Dayangan Sayan Jan 2019

Is Body Mass Index A Risk Factor For Low Cerebral Oxygenation During Spinal Anesthesia In Women Undergoing Cesarean Section? A Preliminary Study, Gülçi̇n Aydin, Cemi̇le Dayangan Sayan

Turkish Journal of Medical Sciences

Background/aim: In this study, it was aimed to investigate the relationship between body mass index (BMI) and cerebral oxygenation during spinal anesthesia in women undergoing cesarean section. This study also aimed to demonstrate whether fetal cord blood oxygenation was affected by maternal BMI and/or delivery time.Materials and methods: The study included parturients with ASA I score undergoing cesarean section under spinal anesthesia in 2015 and 2016. They were divided into two groups according to BMI: Group 1 comprised parturients with BMI of


Characterization And Haplotype Study Of 6 Novel Str Markers Related To The Kcnq1 Gene In Heterogeneous Cardiovascular Disorders In The Iranian Population, Azam Amirian, Zahra Zafari, Zohre Sharifi, Alireza Kordafshari, Morteza Karimipoor, Sirous Zeinali Jan 2019

Characterization And Haplotype Study Of 6 Novel Str Markers Related To The Kcnq1 Gene In Heterogeneous Cardiovascular Disorders In The Iranian Population, Azam Amirian, Zahra Zafari, Zohre Sharifi, Alireza Kordafshari, Morteza Karimipoor, Sirous Zeinali

Turkish Journal of Medical Sciences

No abstract provided.


The Association Of Reduced Bone Density With Paraspinal Muscle Atrophy And Adipose Tissue In Geriatric Patients: A Cross-Sectional Ct Study, Eli̇f Evri̇m Eki̇n, Muhi̇tti̇n Emre Altunrende Jan 2019

The Association Of Reduced Bone Density With Paraspinal Muscle Atrophy And Adipose Tissue In Geriatric Patients: A Cross-Sectional Ct Study, Eli̇f Evri̇m Eki̇n, Muhi̇tti̇n Emre Altunrende

Turkish Journal of Medical Sciences

Background/aim: The aim of the study is to examine the relationship among bone density, adipose tissue, and muscle mass with abdominal CT in geriatric patients.Materials and methods: The study is a retrospective cohort study of patients 65 years and over who underwent abdominal CT for any reason between October 2017 and July 2018. Third lumbar vertebra density, fatty degeneration of the paraspinal muscle, subcutaneous adipose tissue, and mesenteric adipose tissue ratio were evaluated. Results: A total of 312 patients, 144 females and 168 males, were included in the study. Reduced bone density was found in 237 (76%) patients. Reduced bone …


Obesity Perception Survey Among Youth In Turkey: Instrument Development And Test-Retest Reliability, Wasantha Jayawardene, Sali̇h Pinar, Mohammad Torabi, Pengcheng Xun, Mustafa Kami̇l Özer Jan 2019

Obesity Perception Survey Among Youth In Turkey: Instrument Development And Test-Retest Reliability, Wasantha Jayawardene, Sali̇h Pinar, Mohammad Torabi, Pengcheng Xun, Mustafa Kami̇l Özer

Turkish Journal of Medical Sciences

Background/aim: We aimed to develop an instrument that can assess the perceptions and opinions of young people regarding the causes and consequences of obesity and the role of individuals, families, communities, and government in addressing obesity.Materials and methods: A 36-question (101-item) survey was developed by adopting, translating, and revising multiple-choice or Likert-scale questions from existing surveys to assure construct cross-cultural validity. A two-factor mixed-effects model estimated the intraclass correlation coefficient (ICC) to measure the test-retest reliability of questions administered 2 weeks apart to a convenient sample of İstanbul high school and university students, aged 15?25 years (n = 122).Results: The …


The Impact Of Jak/Stat Inhibitor Ruxolitinib On The Genesis Of Lymphoproliferative Diseases, Can Türk, Müfi̇de Okay, Seyhan Türk, Eli̇f Sena Temi̇rci̇, Osama Jawad, Sali̇h Aksu, Ni̇lgün Sayinalp, İbrahi̇m Celaletti̇n Haznedaroğlu Jan 2019

The Impact Of Jak/Stat Inhibitor Ruxolitinib On The Genesis Of Lymphoproliferative Diseases, Can Türk, Müfi̇de Okay, Seyhan Türk, Eli̇f Sena Temi̇rci̇, Osama Jawad, Sali̇h Aksu, Ni̇lgün Sayinalp, İbrahi̇m Celaletti̇n Haznedaroğlu

Turkish Journal of Medical Sciences

Background/aim: Ruxolitinib, a JAK/STAT signaling pathway inhibitor targeted drug, has been approved for the controlling of disease symptoms and splenomegaly in patients with myeloproliferative neoplastic diseases. Recently, it has been proposed that ruxolitinib-induced JAK/STAT pathway inhibition in myelofibrosis is associated with an elevated frequency of aggressive B-cell lymphomas. However, the biological basis and significance of this pharmacobiological adverse event is unknown. The aim of this bioinformatics study is to detect any possible confounding effects of ruxolitinib on the genesis of lymphoproliferative disorders. Materials and methods: The gene expression data were retrieved from the E-MTAB-783 Cancer Genome Project database. Gene expression …


Protective Effects Of Ghrelin On Kidney Tissue In Rats With Partial Ureteral Obstruction, Serhan Çi̇men, Cemal Taşdemi̇r, Ni̇gar Vardi, Burhan Ateş, Seda Taşdemi̇r, Ayla Özaydoğdu Çi̇men Jan 2019

Protective Effects Of Ghrelin On Kidney Tissue In Rats With Partial Ureteral Obstruction, Serhan Çi̇men, Cemal Taşdemi̇r, Ni̇gar Vardi, Burhan Ateş, Seda Taşdemi̇r, Ayla Özaydoğdu Çi̇men

Turkish Journal of Medical Sciences

Background/aim: The aim was to investigate the protective and therapeutic effects of ghrelin, which has antioxidant and antiinflammatory activity, on preventing kidney damage that occurs by induced partial ureteral obstruction in rats.Materials and methods: Twenty-eight adult male rats were included in the study, and the rats were divided into 4 groups. After the laparotomy operation on the sham group, the ureter was identified in the retroperitoneal area and was duly sutured (n = 7). Ghrelin was administered for seven days intraperitoneally, and after the nephrectomy performed on the 15th day, the rats were sacrificed (n = 7). A partial ureteral …


Dermoscopic Aspect Of Verrucous Epidermal Nevi: New Findings, Ömer Faruk Elmas, Necmetti̇n Akdeni̇z Jan 2019

Dermoscopic Aspect Of Verrucous Epidermal Nevi: New Findings, Ömer Faruk Elmas, Necmetti̇n Akdeni̇z

Turkish Journal of Medical Sciences

Background/aim: Verrucous epidermal nevi are cutaneous hamartomas with many clinical variants. Dermoscopic features of verrucous epidermal nevus have rarely been investigated. We aimed to identify dermoscopic findings of the entity which will facilitate the diagnostic process by reducing the use of invasive diagnostic methods. Materials and methods: The study included the patients with histopathologically approved verrucous epidermal nevus. Clinical, dermoscopic, and histopathological features of the patients were retrospectively reviewed and the findings identified were recorded. Dermoscopic examination was performed with a polarized-light handheld dermoscope with 10-fold magnification. Results: The most common dermoscopic features were thick brown circles, thick brown branched …


The Effectiveness Of Renal Nephrometry Score In Ablated Renal Tumors Via Radiofrequency Ablation Or Cryoablation, Seda Aladağ Kurt, Cem Yücel, Suna Özhan Oktar, Gonca Erbaş, Tevfi̇k Si̇nan Sözen, Ali̇ Yusuf Öner Jan 2019

The Effectiveness Of Renal Nephrometry Score In Ablated Renal Tumors Via Radiofrequency Ablation Or Cryoablation, Seda Aladağ Kurt, Cem Yücel, Suna Özhan Oktar, Gonca Erbaş, Tevfi̇k Si̇nan Sözen, Ali̇ Yusuf Öner

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the clinical efficacy of radiofrequency ablation (RFA) and cryotherapy and to scrutinize the therapeutic success of the RENAL (radius, exophytic/endophytic, nearness to collecting system, anterior/posterior, and location) nephrometry score in terms of possible complications and the predictive status of oncological results.Materials and methods: Forty-five patients with biopsy-proven renal cell carcinomas (32 males, 13 females) treated with RFA and cryotherapy were included. Patients were 22-90 years old (average: 59.2 years). Statistical analyses were performed using SPSS for Windows. Results: A total of 79 lesions with dimensions varying between 0.9 and 4.5 cm (average: 2.2 cm) …


Neonatal Outcomes In Syrian And Other Refugees Treated In A Tertiary Hospital In Turkey, İstemi̇ Han Çeli̇k, Zehra Arslan, Di̇lek Ulubaş Işik, Ömer Lütfi̇ Tapisiz, Leyla Mollamahmutoğlu, Ahmet Yağmur Baş, Ni̇hal Demi̇rel Jan 2019

Neonatal Outcomes In Syrian And Other Refugees Treated In A Tertiary Hospital In Turkey, İstemi̇ Han Çeli̇k, Zehra Arslan, Di̇lek Ulubaş Işik, Ömer Lütfi̇ Tapisiz, Leyla Mollamahmutoğlu, Ahmet Yağmur Baş, Ni̇hal Demi̇rel

Turkish Journal of Medical Sciences

Background/aim: Turkey accepts refugees from many countries, principally Syria. More than 2.7 million refugees live in Turkey.We evaluated the neonatal outcomes of refugees. Materials and methods: We retrospectively reviewed the clinical and demographic characteristics of refugee infants born in our hospital between August 2013 and September 2016. Results: Refugees (718 Syrian, 136 Iraqi, 32 Afghani, and 21 of other nationalities) accounted for 907 of 49,413 births. The mean refugee maternal age was lower than that of Turkish women, whereas the gestational age (GA) and birthweight were similar. Refugees required fewer cesarean sections but exhibited greater small- and large-for-GA rates (P < 0.05). Refugee and Turkish infant mortality rates did not differ significantly (0.8 vs. 0.4%). Eighty-nine (12.3%) refugee neonates and 6682 (13.5%) Turkish neonates were admitted to our neonatal intensive care unit (NICU). Jaundice and perinatal asphyxia were significantly more common in refugees, whereas respiratory distress syndrome, GA ≤32 weeks, and infant birthweight


Three Dimensional Printing And Biomaterials In The Repairment Of Bone Defects; Hydroxyapatite Pla Filaments, İsmai̇l Kaya, Meryem Cansu Şahi̇n, İlker Deni̇z Ci̇ngöz, Nevi̇n Aydin, Murat Atar, Ceren Kizmazoğlu, Sali̇h Kavuncu, Hasan Emre Aydin Jan 2019

Three Dimensional Printing And Biomaterials In The Repairment Of Bone Defects; Hydroxyapatite Pla Filaments, İsmai̇l Kaya, Meryem Cansu Şahi̇n, İlker Deni̇z Ci̇ngöz, Nevi̇n Aydin, Murat Atar, Ceren Kizmazoğlu, Sali̇h Kavuncu, Hasan Emre Aydin

Turkish Journal of Medical Sciences

Background/aim: Application fields of bone tissue engineering studies continue to expand. New biocompatible materials aimed to improve bone repairment and regeneration of implants are being discovered everyday by scientists, engineers, and surgeons. Our objective in this study is to combine polylactic acid which is a polymer with hydroxyapatite in the repairment of bone defects considering the increased need by medical application fields. Materials and methods: After 750 g of PLA with a diameter of 2.85 mm was granulated into minimum particles, these particles were homogenously mixed with hydroxyapatite prepared in laboratory environment. Using this mixture, HA-PLA filament with a diameter …


Is Leptin Receptor Expression Triggered In The Case Of Embryo Transfer To Endometrium Coculture?, İskender Kaplanoğlu, Gülnur Take Kaplanoğlu, Özgür Çinar, Güleser Göktaş, Serdar Di̇lbaz, Cemi̇le Merve Seymen Jan 2019

Is Leptin Receptor Expression Triggered In The Case Of Embryo Transfer To Endometrium Coculture?, İskender Kaplanoğlu, Gülnur Take Kaplanoğlu, Özgür Çinar, Güleser Göktaş, Serdar Di̇lbaz, Cemi̇le Merve Seymen

Turkish Journal of Medical Sciences

Background/aim: A synchronized dialogue between maternal and embryonic tissues is required for successful implantation. Low uterine receptivity is responsible for two-thirds of implantation failures and leptin is effective in the physiology of reproduction by binding to specific receptors. In this study, we investigateleptin receptor expression in cases of embryo transfer to endometrial coculture. Materials and methods: Biopsy materials were taken from 20 females with indication for coculture application and were cultured in an appropriate medium after the epithelial cells were isolated. The grown cells were cultured in chamber slides as the first group. For the second group, day 3 embryo …


The Association Between Levels Of Inflammatory Markers In Autistic Children Compared To Their Unaffected Siblings And Unrelated Healthy Controls, Loai Alzghoul, Sultan Abdelhamid, Ahmad Yanis, Yasmeen Qwaider, Mohammad Aldahabi, Suzan Albdour Jan 2019

The Association Between Levels Of Inflammatory Markers In Autistic Children Compared To Their Unaffected Siblings And Unrelated Healthy Controls, Loai Alzghoul, Sultan Abdelhamid, Ahmad Yanis, Yasmeen Qwaider, Mohammad Aldahabi, Suzan Albdour

Turkish Journal of Medical Sciences

Background/aim: Autism spectrum disorder (ASD) describes a range of neurodevelopmental disabilities that impair behavior and communication. Although it is relatively prevalent, the pathophysiology is still subject to speculation and debate. The aim of this study is to identify a possible association between interleukin-6, -8, -9, and -10 and tumor necrosis factor alpha (TNF- ∝) in autism among Jordanian children by comparing the plasma levels of these cytokines in autistic children with those of their unaffected siblings and unrelated healthy controls. Materials andmethods: In this study, 80 Jordanian children under the age of 12 with diagnosed autism were selected. For comparison, …


Association Between Ppargc1a Single Nucleotide Polymorphisms And Increased Risk Of Nonalcoholic Fatty Liver Disease Among Iranian Patients With Type 2 Diabetes Mellitus, Leila Saremi, Shirin Lotfipanah, Masumeh Mohammadi, Hassan Hosseinzadeh, Zahra Hosseini-Khah, Behrooz Johari, Zohreh Saltanatpour Jan 2019

Association Between Ppargc1a Single Nucleotide Polymorphisms And Increased Risk Of Nonalcoholic Fatty Liver Disease Among Iranian Patients With Type 2 Diabetes Mellitus, Leila Saremi, Shirin Lotfipanah, Masumeh Mohammadi, Hassan Hosseinzadeh, Zahra Hosseini-Khah, Behrooz Johari, Zohreh Saltanatpour

Turkish Journal of Medical Sciences

Background/aim: Environmental and genetic factors may play a major role in the development of nonalcoholic fatty liver disease (NAFLD) among people with obesity and type 2 diabetes mellitus. Based on the fact that PGC-1?, as the protein encoded by the PPARGC1A gene, plays a key role in energy metabolism pathways, it has been hypothesized that polymorphisms within the PPARGC1Agene may be associated with increased risks of NAFLD. Thus, this study was designed to evaluate the Gly482Ser polymorphism (rs8192678) within the PPARGC1A gene and its association with the increased risk of NAFLD in Iranian patients with type 2 diabetes.Materials and methods: …


Efficiency Of Pulsed Electromagnetic Fields On Pain, Disability, Anxiety, Depression, And Quality Of Life In Patients With Cervical Disc Herniation: A Randomized Controlled Study, Erkam Hattapoğlu, İbrahi̇m Batmaz, Banu Di̇lek, Mehmet Karakoç, Serda Em, Remzi̇ Çevi̇k Jan 2019

Efficiency Of Pulsed Electromagnetic Fields On Pain, Disability, Anxiety, Depression, And Quality Of Life In Patients With Cervical Disc Herniation: A Randomized Controlled Study, Erkam Hattapoğlu, İbrahi̇m Batmaz, Banu Di̇lek, Mehmet Karakoç, Serda Em, Remzi̇ Çevi̇k

Turkish Journal of Medical Sciences

Background/aim: In this study, it was aimed to investigate the effects ofpulsed electromagnetic field(PEMF) therapy on pain, disability, psychological state, and quality of life in cervical disc herniation.Materials and methods: Patients were randomly divided into two groups, including Group 1, which received a therapy consisting of transcutaneous electrical nerve stimulation (TENS), hot pack (HP), and PEMF, and Group 2, which received a magnetic field (sham magnetic field) without current flow in addition to TENS and HP therapy. Pain was assessed by a visual analog scale (VAS, 0?10 cm). The other outcome measures were function (Neck Pain and Disability Scale), anxiety-depressive …


Comparison Of Intestinal Ischemia After On-Pump Versus Off-Pump Coronary Artery Bypass Grafting Surgery, Lütfi̇ Soylu, Oğuz Uğur Aydin, Mehmet Yildiz, Hacer Serdaroğlu, Murat Kurtoğlu, Sedat Karademi̇r Jan 2019

Comparison Of Intestinal Ischemia After On-Pump Versus Off-Pump Coronary Artery Bypass Grafting Surgery, Lütfi̇ Soylu, Oğuz Uğur Aydin, Mehmet Yildiz, Hacer Serdaroğlu, Murat Kurtoğlu, Sedat Karademi̇r

Turkish Journal of Medical Sciences

Acute mesenteric ischemia (AMI), one of the gastrointestinal system complications, which occurs following cardiac surgery, is challenged in the literature with a diminished incidence of AMI by heart surgery without cardiopulmonary bypass (CPB) or with pulsatile CPB. This study aims to compare the incidence and mortality rate of mesenteric ischemia in a series of consecutive patients undergoing coronary artery bypass grafting (CABG) through on-pump and off-pump techniques.Materials and methods: This study included patients who underwent CABG between 1 January 2010 and 31 June 2016. All patients were divided into two groups: Group 1 comprised 6396 CABG patients operated on with …


Abnormal Retinal Microvasculature Found In Active Rheumatoid Arthritis:A Different Perspective Of Microvascular Health, Hakan Babaoğlu, Ata Baytaroğlu, Murat Torğutalp, Abdulsamet Erden, Si̇bel Kadayifçilar, Umut Kalyoncu Jan 2019

Abnormal Retinal Microvasculature Found In Active Rheumatoid Arthritis:A Different Perspective Of Microvascular Health, Hakan Babaoğlu, Ata Baytaroğlu, Murat Torğutalp, Abdulsamet Erden, Si̇bel Kadayifçilar, Umut Kalyoncu

Turkish Journal of Medical Sciences

We aimed to assess the association between retinal vascular caliber (RVC) scores and disease activity in rheumatoid arthritis (RA) patients.Materials and methods: Forty-seven RA patients, 32 systemic lupus erythematosus (SLE) patients, and 45 healthy people were enrolled. RA and SLE patients were subdivided into groups according to C-reactive protein (CRP) levels. RA patients were also grouped according to Disease Activity Score-28 (DAS-28). Fundus photography was performed for all patients. RVC was summarized as the central retinal artery and vein equivalents (CRAE and CRVE).Results: Mean CRVE for RA patients was 213.3 ± 17.8 µm compared with 209.2 ± 14.1 µm for …


High Rates Of Malnutrition And Epilepsy: Two Common Comorbidities In Children With Cerebral Palsy, Kürşad Aydin, Ayşe Kartal, Esma Keleş Alp Jan 2019

High Rates Of Malnutrition And Epilepsy: Two Common Comorbidities In Children With Cerebral Palsy, Kürşad Aydin, Ayşe Kartal, Esma Keleş Alp

Turkish Journal of Medical Sciences

The aim of this study was to evaluate the nutritional status of children with cerebral palsy and determine the particular characteristics of the disorder. Materials and methods: The nutritional status of the children was assessed by the Gomez classification using weight-for-age. The Gross Motor Function Classification System was used to determine the gross and fine motor functions.Results: The study was conducted with 197 children (58.4% males) between the ages of 1 and 18 years old. Asphyxia (44.1%) was the primary etiological factor, and spastic quadriplegia (41.6%) was the most common type of cerebral palsy. Malnutrition was the most frequent comorbidity …


Differentiation Between Intestinal Behçet's Disease And Crohn's Disease Based On Endoscopy, Jing Fen Ye, Jian Long Guan Jan 2019

Differentiation Between Intestinal Behçet's Disease And Crohn's Disease Based On Endoscopy, Jing Fen Ye, Jian Long Guan

Turkish Journal of Medical Sciences

Differentiating intestinal Behçet's disease (BD) from Crohn's disease (CD) is highly challenging, as they often mimic each other in terms of clinical manifestations. Endoscopy is an important modality for distinguishing bowel lesions. The study was designed to identify clinical manifestations that are easily confused and to evaluate the efficacy of endoscopy for distinguishing intestinal BD from CD by several overlapping signs.Materials and methods: The data from 111 patients with intestinal BD and 81 patients with CD were retrospectively analyzed. Logistic regression was applied to establish a prediction model based on endoscopic findings for the differential diagnosis. The diagnostic efficacy of …


The Role Of Hepcidin, Gdf15, And Mitoferrin-1 In Iron Metabolism Of Polycythemia Vera And Essential Thrombocytosis Patients, Canan Albayrak Yaşar, Pinar Tarkun, Eli̇f Bi̇rtaş Ateşoğlu, Fatma Ceyla Eraldemi̇r, Özgür Doğa Özsoy, Esra Terzi̇ Demi̇rsoy, Özgür Mehtap, Ayfer Gedük, Abdullah Haci̇hani̇fi̇oğlu Jan 2019

The Role Of Hepcidin, Gdf15, And Mitoferrin-1 In Iron Metabolism Of Polycythemia Vera And Essential Thrombocytosis Patients, Canan Albayrak Yaşar, Pinar Tarkun, Eli̇f Bi̇rtaş Ateşoğlu, Fatma Ceyla Eraldemi̇r, Özgür Doğa Özsoy, Esra Terzi̇ Demi̇rsoy, Özgür Mehtap, Ayfer Gedük, Abdullah Haci̇hani̇fi̇oğlu

Turkish Journal of Medical Sciences

GDF15, hepcidin and mitoferrin-1 (mfrn-1) are proteins involved in systemic iron regulation. There are no studies in the literature demonstrating the serum mfrn-1 levels in polycythemia vera (PV) and essential thrombocythemia (ET) patients. The aim of this study was to investigate GDF15, hepcidin and mfrn-1 levels in PV and ET patients.Materials and methods: Ten PV, 17 ET patients, and 27 healthy controls (HCs) were enrolled. GDF15, hepcidin and mfrn-1 values were measured with enzyme-linked immunosorbent assay (ELISA).Results: GDF15 levels were higher in the myeloproliferative neoplasm (MPN) group (P = 0.002). Hepcidin levels were not different between MPN patients and HCs. …


A Neglected Causative Agent In Diabetic Foot Infection: A Retrospective Evaluation Of 13 Patients With Fungal Etiology, Anil Murat Ozturk, Meltem Taşbakan, Di̇lek Yeşi̇m Meti̇n, Can Yener, Serhat Uysal, Ilgin Yildirim Şi̇mşi̇r, İlgen Ertam, Hüsnü Pullukçu, Bi̇lgi̇n Arda, Şevki̇ Çeti̇nkalp Jan 2019

A Neglected Causative Agent In Diabetic Foot Infection: A Retrospective Evaluation Of 13 Patients With Fungal Etiology, Anil Murat Ozturk, Meltem Taşbakan, Di̇lek Yeşi̇m Meti̇n, Can Yener, Serhat Uysal, Ilgin Yildirim Şi̇mşi̇r, İlgen Ertam, Hüsnü Pullukçu, Bi̇lgi̇n Arda, Şevki̇ Çeti̇nkalp

Turkish Journal of Medical Sciences

Clinicians often neglect fungal infections and do not routinely investigate deep tissue from the wound for fungal culture and sensitivity due to insufficient information in the literature. In this study, we aimed to evaluate fungal etiology of invasive fungal diabetic foot which is rarely reported in the literature.Materials and methods: The patients who were unresponsive to antibiotic therapy and those with positive fungal in bone or deep tissue culture were enrolled in the study. Detailed hospital records were retrieved for demographics and clinical features. Results: A total of 13 patients who were diagnosed with invasive fungal diabetic foot (ten females, …


Colostrum Immunoglobulins And Oxidative Capacity May Be Affected By Infant Sex And Maternal Age And Parity, Davut Si̇nan Kaplan, Cahi̇t Bağci, Mustafa Örkmez, Özge Kömürcü Karuserci̇, Seyhun Sucu, Haki̇m Çeli̇k, Seyi̇than Taysi Jan 2019

Colostrum Immunoglobulins And Oxidative Capacity May Be Affected By Infant Sex And Maternal Age And Parity, Davut Si̇nan Kaplan, Cahi̇t Bağci, Mustafa Örkmez, Özge Kömürcü Karuserci̇, Seyhun Sucu, Haki̇m Çeli̇k, Seyi̇than Taysi

Turkish Journal of Medical Sciences

The aims of this study were to determine the levels of the total antioxidant status (TAS), the total oxidant status (TOS), the oxidative stress index (OSI), and the concentration of immunoglobulin A (IgA) and M (IgM) in colostrum, and evaluate relationships between these parameters and maternal age, maternal parity, and infant sex. Materials and methods: The analysis was performed in serum samples of colostrum which were collected from 90 mothers on the first day of lactation between 10:00 and 12:00 AM.Results: The measurements established that no significant association existed between the TAS level of colostrum and parity, maternal age, or …


8-Hydroxy-2'-Deoxyguanosine As A Biomarker Of Oxidative Stress In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease, Xing Liu, Kaili Deng, Sixia Chen, Yunshi Zhang, Jing Yao, Xiaoqin Weng, Yang Zhang, Tianming Gao, Ganzhu Feng Jan 2019

8-Hydroxy-2'-Deoxyguanosine As A Biomarker Of Oxidative Stress In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease, Xing Liu, Kaili Deng, Sixia Chen, Yunshi Zhang, Jing Yao, Xiaoqin Weng, Yang Zhang, Tianming Gao, Ganzhu Feng

Turkish Journal of Medical Sciences

8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a biomarker of oxidative stress and has been implicated in many diseases. The aim of this study was to investigate the clinical value of plasma 8-OHdG level in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Materials and methods: A total of 154 subjects were enrolled in this study, including 20 healthy volunteers, 24 COPD patients in the stable phase, and 110 AECOPD patients. Peripheral blood samples, demographic information, and clinical characteristics were collected from all subjects at the time of being recruited into the study. Plasma 8-OHdG level was detected by enzyme-linked immunosorbent assay.Results: 8-OHdG …


Serum Adropin Levels In Psoriasis Vulgaris And Its Relation With Metabolic Parameters, Selma Korkmaz, Gülben Sayilan Özgün Jan 2019

Serum Adropin Levels In Psoriasis Vulgaris And Its Relation With Metabolic Parameters, Selma Korkmaz, Gülben Sayilan Özgün

Turkish Journal of Medical Sciences

Adropin is a peptide-structure hormone that plays a role in preventing the development of insulin resistance, which has been linked to obesity and metabolic regulation. The purpose of this study is to assess serum adropin levels and their relationship with metabolic parameters in psoriasis vulgaris patients both with and without metabolic syndrome (MetS).Materials and methods: Fifty-three patients and 26 healthy controls were included in this study. Serum adropin levels, fasting blood glucose, fasting serum insulin, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, total cholesterol, and triglyceride levels of all participants were analyzed. Enzyme-linked immunosorbent assay was used to measure serum adropin …


A Comparison Of The Effects Of Mirror Therapy And Phantom Exercises On Phantom Limb Pain, Bahar Külünkoğlu, Fati̇h Erbahçeci̇, Afra Alkan Jan 2019

A Comparison Of The Effects Of Mirror Therapy And Phantom Exercises On Phantom Limb Pain, Bahar Külünkoğlu, Fati̇h Erbahçeci̇, Afra Alkan

Turkish Journal of Medical Sciences

Although mirror therapy (MT) and phantom exercises (PE) have been shown to reduce pain, the efficacy of these methods in terms of pain, quality of life (QoL), and psychological status (PS) has not been investigated and compared to date. The aim of this study was to determine whether there is any difference between MT and PE in the treatment of phantom limb pain (PLP).Materials and methods: Forty unilateral transtibial amputees (aged 18-45 years) participated in this study. The subjects were randomly divided into `MT group' and `PE group'. QoL was assessed using Short-Form 36 (SF-36), psychological status using the Beck …


Which Nostril Should Be Used For Nasotracheal Intubation With Airtraq Nt®: The Right Or Left? A Randomized Clinical Trial, Zehra İpek Arslan Aydin, Neşe Türkyilmaz Jan 2019

Which Nostril Should Be Used For Nasotracheal Intubation With Airtraq Nt®: The Right Or Left? A Randomized Clinical Trial, Zehra İpek Arslan Aydin, Neşe Türkyilmaz

Turkish Journal of Medical Sciences

Nasotracheal Airtraq is specifically designed to improve the glottis view and ease the nasotracheal intubation process in normal and difficult cases. Materials and methods: After Ethics committee approval, we decided to enroll 40 patients with an ASA physical status of I or II, between 18 and 70 years of age undergoing elective maxillofascial, oral, and double chin surgery to determine which nostril is more suitable for nasotracheal intubation with nasotracheal Airtraq. Patients were randomized into the right and left nostril groups. Results: Demographic and airway characteristics were similar among the groups. Nasotracheal intubation through the right nostril was shorter than …


Association Of Common Il-10 Promoter Gene Variants With The Susceptibility To Head And Neck Cancer In Tunisia, Lamia Makni, Cherif Ben Hamda, Abrar Al Ansari, Oussema Souaiai, Ezzedine Gazouani, Amel Mezlini, Wassim Y. Almawi, Besma Yacoubi-Loueslati Jan 2019

Association Of Common Il-10 Promoter Gene Variants With The Susceptibility To Head And Neck Cancer In Tunisia, Lamia Makni, Cherif Ben Hamda, Abrar Al Ansari, Oussema Souaiai, Ezzedine Gazouani, Amel Mezlini, Wassim Y. Almawi, Besma Yacoubi-Loueslati

Turkish Journal of Medical Sciences

Background/aim: We investigated the association of three IL-10 promoter single-nucleotide polymorphisms and altered IL-10 plasma levels with the risk of head and neck cancer (HNC). Materials and methods: Study subjects comprised 194 HNC patients [137 nasopharyngeal cancer (NPC) and 57 laryngeal cancer (LC)], and 263 healthy controls. Genotyping of rs1800896 (-1082A>G), rs1800871 (-819C>T), and rs1800872 (-592A>C) IL-10 variants was performed by real-time PCR; IL-10 levels were measured by enzyme amplified immuno sensitivity assay (EAISA). Results: Carriage of rs1800896 A/A genotype was more frequent in the HNC and NPC cases, but was less frequent in the controls than …


Comparison Of Conventional And Modern Methods In Determining Ischemic Stroke Etiology By General And Stroke Neurologists, Refi̇k Kunt, Mustafa Kürşad Kutluk, Bedi̇le İrem Ti̇fti̇kci̇oğlu, Nazi̇re Efser Yeşi̇m Afşar Fak, Ali̇ Kemal Erdemoğlu, Muhteşem Gedi̇zli̇oğlu, Vesi̇le Öztürk Jan 2019

Comparison Of Conventional And Modern Methods In Determining Ischemic Stroke Etiology By General And Stroke Neurologists, Refi̇k Kunt, Mustafa Kürşad Kutluk, Bedi̇le İrem Ti̇fti̇kci̇oğlu, Nazi̇re Efser Yeşi̇m Afşar Fak, Ali̇ Kemal Erdemoğlu, Muhteşem Gedi̇zli̇oğlu, Vesi̇le Öztürk

Turkish Journal of Medical Sciences

This study aimed to investigate the consistency between stroke and general neurologists in subtype assignment using the Trial of ORG-10172 in Acute Stroke Treatment (TOAST) and Causative Classification of Stroke (CCS) systems.Materials and methods: Fifty consecutive acute ischemic stroke patients admitted to the stroke unit were recruited. Patients were classified by two stroke and two general neurologists, each from different medical centers, according to TOAST followed by the CCS. Each neurologist was assessed for consistency and compliance in pairs. Concordance among all four neurologists was investigated and evaluated using the kappa (ĸ) value.Results: The kappa (ĸ) value of diagnostic compliance …


Role Of Iliac Crest Tangent In Correct Numbering Of Lumbosacral Transitional Vertebrae, Nesri̇n Gündüz, Gülci̇n Durukan Günaydin, Mehmet Bi̇lgi̇n Eser, Ahmet Aslan, Adnan Kabaali̇oğlu Jan 2019

Role Of Iliac Crest Tangent In Correct Numbering Of Lumbosacral Transitional Vertebrae, Nesri̇n Gündüz, Gülci̇n Durukan Günaydin, Mehmet Bi̇lgi̇n Eser, Ahmet Aslan, Adnan Kabaali̇oğlu

Turkish Journal of Medical Sciences

The iliac crest tangent (ICT) has recently emerged as a reliable landmark to correctly number the lumbosacral transitional vertebrae (LSTV). We retrospectively evaluated the reproducibility and accuracy of the ICT as a landmark in subjects without disc degeneration.Materials and methods: Fifty-eight patients with LSTV [19 female, 41 (26-52) years] and 55 controls without LSTV [23 female, 40 (26-55) years] who had undergone spinal computed tomography were included. The ICT was drawn on the coronal images, with the cursor in the sagittal view set to the posterior ⅓ of the vertebral body located one level above the LSTV. When more than …


Calcification Of Breast Artery As Detected By Mammography: Association With Coronary And Aortic Calcification, Ayşegül İdi̇l Soylu, Korhan Soylu, Ramazan Aydin, Fati̇h Uzunkaya, Keri̇m Aslan, Ahmet Veysel Polat Jan 2019

Calcification Of Breast Artery As Detected By Mammography: Association With Coronary And Aortic Calcification, Ayşegül İdi̇l Soylu, Korhan Soylu, Ramazan Aydin, Fati̇h Uzunkaya, Keri̇m Aslan, Ahmet Veysel Polat

Turkish Journal of Medical Sciences

Coronary artery calcification (CAC) and aortic calcification (AC) are significant risk factors for coronary atherosclerosis. This study investigated how breast arterial calcification (BAC) detected from routine mammography correlates with coronary artery calcification and aortic calcification.Materials and methods: A total of 404 female patients above 40 years of age who, within a 6-month period, had undergone thoracic computed tomography and mammography for various reasons were screened retrospectively at our clinic. Mammographies were assessed for BAC and thoracic CT investigations were assessed for CAC and AC. Patients included in the study were scored as 0 (none), 1 (mild), 2 (moderate), or 3 …


Determination Of Medication Adherence And Related Factors Among People Living With Hiv/Aids In A Turkish University Hospital, Erdal Ceylan, Ayşegül Koç, Ahmet Çağkan İnkaya, Serhat Ünal Jan 2019

Determination Of Medication Adherence And Related Factors Among People Living With Hiv/Aids In A Turkish University Hospital, Erdal Ceylan, Ayşegül Koç, Ahmet Çağkan İnkaya, Serhat Ünal

Turkish Journal of Medical Sciences

Widespread use of antiretroviral treatment (ART) has led to decrease in the incidence of HIV/AIDS-related mortality. Besides the availability of ART, medication adherence is essential for treatment success. There is a scarcity of data reported from Turkey regarding ART adherence among people living with HIV/AIDS (PLWHA). Therefore, this study was undertaken to determine medication adherence and related factors among PLWHA in Turkey.Materials and methods: The sample consisted of 158 PLWHA, who were being followed up at Infectious Diseases Outpatient Clinic of Hacettepe University Hospital. Data were collected using an individual questionnaire and the Turkish version of the Morisky Medication Adherence …