Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- Sheep (141)
- Turkey (139)
- Dog (138)
- Cattle (118)
- COVID-19 (110)
-
- Oxidative stress (104)
- Children (97)
- Rat (94)
- Prevalence (88)
- Treatment (76)
- ELISA (75)
- Pregnancy (75)
- Growth (72)
- Mortality (71)
- Inflammation (67)
- PCR (59)
- Immunohistochemistry (58)
- Apoptosis (57)
- Broiler (57)
- Goat (57)
- Ultrasonography (54)
- Chicken (53)
- Prognosis (53)
- Breast cancer (51)
- Cow (51)
- Magnetic resonance imaging (50)
- Diagnosis (49)
- Lamb (49)
- Obesity (49)
- Liver (47)
- Publication Year
Articles 1321 - 1350 of 8080
Full-Text Articles in Medicine and Health Sciences
Effects Of Feeding Varying Levels Of Inoculated Compost On Productive Performance, Egg Quality Traits, Organoleptic Properties, And Immune Response Of Commercial Layers, Muhammad Irfan, Shahid Mehmood, Athar Mahmud, Aftab Ahmad Anjum
Effects Of Feeding Varying Levels Of Inoculated Compost On Productive Performance, Egg Quality Traits, Organoleptic Properties, And Immune Response Of Commercial Layers, Muhammad Irfan, Shahid Mehmood, Athar Mahmud, Aftab Ahmad Anjum
Turkish Journal of Veterinary & Animal Sciences
A study was conducted to evaluate the impact of varying dietary inoculated compost levels on production performance, egg quality traits, and immune response of white laying hens (LSL) during the peak production phase (28 to 40 weeks). For this purpose, a total of 270 birds were randomly distributed into 5 dietary groups with 6 replicates each in techno battery cages having 9 birds per replicate following completely randomized design. Experimental diets were comprised of an increasing level of inoculated compost (0, 3, 6, 9, and 12%) and each diet was balanced (iso-caloric and iso-nitrogenous). The control group birds fed a …
Cheyletiella Yasguri Smiley, 1965 (Acarina: Cheyletiellidae) Infestations In Six Puppies In Kocaeli Province Of Turkey, And Successful Treatment With Selamectin, Onur Ceylan, Önder Öztürk
Cheyletiella Yasguri Smiley, 1965 (Acarina: Cheyletiellidae) Infestations In Six Puppies In Kocaeli Province Of Turkey, And Successful Treatment With Selamectin, Onur Ceylan, Önder Öztürk
Turkish Journal of Veterinary & Animal Sciences
Cheyletiellosis is a highly contagious infestation caused by Cheyletiella mites, particularly in pets. This clinical case report was performed to give information about canine cheyletiellosis in 45-days-old Poodle puppies showing mainly pruritus and dandruff symptoms. Mites were detected in stereo microscopic examination of hair and skin scraping samples collected from dogs brought to a private veterinary clinic in Kocaeli province of Turkey. All collected materials were preserved in eppendorf tubes containing 70% ethanol and sent to the parasitology laboratory for species identification. Mite preparations for microscopic examination were prepared, and the species causing infestations in puppies was identified as Cheyletiella …
Effect Of Biopreservative Cultures On The Shelf Life Of Modified Atmosphere Packaged Chicken Cocktail Sausage, Sevgi̇ Ataş, Gökhan Kürşad İnci̇li̇, Hali̇l Durmuşoğlu, Mehmet Çalicioğlu
Effect Of Biopreservative Cultures On The Shelf Life Of Modified Atmosphere Packaged Chicken Cocktail Sausage, Sevgi̇ Ataş, Gökhan Kürşad İnci̇li̇, Hali̇l Durmuşoğlu, Mehmet Çalicioğlu
Turkish Journal of Veterinary & Animal Sciences
The present study was undertaken to extend the shelf life of modified atmosphere packaged chicken cocktail sausages by using biopreservative cultures (Lactobacillus sakei (B-2) and Lactobacillus curvatus (B-LC-48)). According to the results, cocktail sausages in control group stored either at 4 °C or 10 °C were spoiled as of day 28 due to a decrease in average flavor score and general acceptance score and increases in mesophilic and psychrotrophic colony counts (p < 0.05). In bioprotective cultures treated groups, no spoilage was detected throughout the 60-day storage at 4 °C, whereas those products stored at 10 °C spoiled as of day 42. Results of this study indicated that the bioprotective cultures tested were able to control the spoilage bacteria by establishing bacterial predominance starting from the first day of the shelf life (p < 0.05). It was concluded that these cultures can be useful in chicken cocktail sausages production, especially when a proper cold chain cannot be guaranteed during transportation and at retail.
Comparative Efficiency Of Five Mathematical Functions In Modelling The First Lactation Milk Yield Of Kankrej Cattle, Thiruvothur Venkatesan Raja, Achintya Kumar Das, Satish Kumar Rathee, Umesh Singh, Sushil Kumar, Bharat Singh Rathod, Harshad Panchasara
Comparative Efficiency Of Five Mathematical Functions In Modelling The First Lactation Milk Yield Of Kankrej Cattle, Thiruvothur Venkatesan Raja, Achintya Kumar Das, Satish Kumar Rathee, Umesh Singh, Sushil Kumar, Bharat Singh Rathod, Harshad Panchasara
Turkish Journal of Veterinary & Animal Sciences
Modelling of first lactation milk yield of Kankrej cattle was done using five different non-linear mathematical functions viz., exponential decline function (EDF), gamma function (GF), inverse polynomial function (IPF), mixed log function (MLF) and parabolic exponential function (PEF). We compared their efficiency in describing variations in first lactation milk yield of animals maintained under field conditions. A total of 3994 fortnightly daily milk records of 203 Kankrej cattle calved during the years between 2011 and 2017 at farmers? herds in the Banaskantha region of Gujarat State, India were utilized for the study. The PROC NLIN procedure of Statistical Analysis Software …
Trend Topics In Animal Science: A Bibliometric Analysis Using Citespace, Fatma Yardi̇bi̇, Mehmet Zi̇ya Firat, Emi̇ne Çeti̇n Teke
Trend Topics In Animal Science: A Bibliometric Analysis Using Citespace, Fatma Yardi̇bi̇, Mehmet Zi̇ya Firat, Emi̇ne Çeti̇n Teke
Turkish Journal of Veterinary & Animal Sciences
The aim of this study was the identification of trends topics in animal science in the last five years using bibliometric analysis. The research data consisted of 6972 studies published between 2015 and 2019 in the top five journals of animal science field, according to the Journal Citation Reports. The journals were analyzed in terms of number and types of publications, author, institution, country productivity, citation analysis, and citation burst. In the study, emerging trends and animal science intellectual structures were visualized with social network analysis. The evidence revealed in this study suggests that `genomic prediction' is the most effective …
Effects Of Partial Replacement Of Conventional Limestone With Dietary Micro-Calciumcarbonate On Performance, Egg Quality, Hematology, And Calcium Metabolism Of Laying Hens During Peak Production, Eyüp Eren Gültepe, Aamir Iqbal, Cangi̇r Uyarlar, İbrahi̇m Sadi̇ Çeti̇ngül, Ümi̇t Özçinar, İsmai̇l Bayram
Effects Of Partial Replacement Of Conventional Limestone With Dietary Micro-Calciumcarbonate On Performance, Egg Quality, Hematology, And Calcium Metabolism Of Laying Hens During Peak Production, Eyüp Eren Gültepe, Aamir Iqbal, Cangi̇r Uyarlar, İbrahi̇m Sadi̇ Çeti̇ngül, Ümi̇t Özçinar, İsmai̇l Bayram
Turkish Journal of Veterinary & Animal Sciences
The present study was conducted to evaluate the effects of limestone replacement with dietary micro-calcium carbonate (MCC) on performance, egg quality, and serum Ca metabolism in peak-phase laying hens. A total of 120 laying hens (30 wk of age) were assigned to 1 control or 4 treatment groups for 8 weeks. Half of the total limestone was replaced by calcite in different particle sizes in the treatment groups (1, 20, 40, and 100 µm) and by fine limestone (~2 mm) in control. During the experiment, egg production and mass decreased (p < 0.05); however, eggshell thickness increased in hens fed with calcite groups compared to the control fed birds. There was a contrast between control vs. treatment, and a negative linear trend (p = 0.11) with the particle sizes for feed conversion ratio (FCR) was recorded. The different particle size of calcite had no effect on feed consumption, egg quality parameters, and hematology parameters of serum. However, the serum calcium (p = 0.01) and vitamin D (p < 0.0001) levels were affected by calcite, serum parathyroid hormone, calcitonin, phosphorus levels, and Ca:P ratio were not affected. The effects of dietary calcite sources may differ from conventional or nano-sized calcium carbonate sources in laying hens, especially for Vit D metabolism.
Evaluation Of Cyp19 As A Candidate Gene For Milk Production Traits In Native Cattle Andbuffalo Populations Of Southern India, Sudhakar Krovvidi, Thiruvenkadan Kannan Aranganoor, Saravanan Ramasamy, Vinoo Regula, Muralidhar Metta, Jeyakumar Mani
Evaluation Of Cyp19 As A Candidate Gene For Milk Production Traits In Native Cattle Andbuffalo Populations Of Southern India, Sudhakar Krovvidi, Thiruvenkadan Kannan Aranganoor, Saravanan Ramasamy, Vinoo Regula, Muralidhar Metta, Jeyakumar Mani
Turkish Journal of Veterinary & Animal Sciences
Candidate gene approach facilitates searching causative polymorphisms that influence quantitative traits. Biosynthesis of estrogen catalyzed by aromatase, a product of the CYP19 gene affect lactogenesis. The objective of the study was to determine the polymorphism in the promoter region of CYP19 gene by PCR-RFLP and was undertaken on 502 bovine species belonging to Ongole (Bos indicus), Holstein Friesian crossbred, Jersey crossbred cattle, and Murrah buffaloes reared across Southern India. The frequency of the CYP19A allele was 0.90, 0.88, and 0.77 in Jersey crossbred, HF crossbred, and Ongole cattle, respectively. The BB genotypes could not be observed in Jersey crossbred cattle. …
Single Nucleotide Polymorphisms Of Gdf9 Gene/Exon 2 Region And Their Associationswith Milk Yield And Milk Content Traits In Karakaş And Norduz Sheep Breeds, Hasan Koyun, Selahaddi̇n Ki̇raz, Serhat Karaca, Seyrani̇ Koncagül, Ayhan Yilmaz, Kadi̇r Karakuş, Abdullah Yeşi̇lova, Turgut Aygün
Single Nucleotide Polymorphisms Of Gdf9 Gene/Exon 2 Region And Their Associationswith Milk Yield And Milk Content Traits In Karakaş And Norduz Sheep Breeds, Hasan Koyun, Selahaddi̇n Ki̇raz, Serhat Karaca, Seyrani̇ Koncagül, Ayhan Yilmaz, Kadi̇r Karakuş, Abdullah Yeşi̇lova, Turgut Aygün
Turkish Journal of Veterinary & Animal Sciences
Karakaş and Norduz sheep have been adapted to the Lake Van region of Turkey for many years as being domestic genetic resources and meat, milk, and fleece traits are a reliable economic resource especially preferred by small family businesses around the area. In this study, the data set consisted of milk yield (MY) and milk content components; milk fat (MF), fat-free dry matter (FFDM), dry matter (DM), protein (Pro), lactose (Lac), pH, acidity H (aH), and lactic acid (Lac). Besides, Karakaş (n = 30) and Norduz (n = 26) sheep were chosen to investigate based on the SNP method. Correspondingly, …
Characterization And Relationship Between Bulk Tank Milk Composition And Compostbedded Variables From Dairy Barns In Rio Grande Do Sul State, Brazil, Karise Fernanda Nogara, Marcos Busanello, Ione Maria Pereira Haygert-Velho, Maity Zopollatto, Karen Dal Magro Frigeri, Paulo Sergio Goes Almeida
Characterization And Relationship Between Bulk Tank Milk Composition And Compostbedded Variables From Dairy Barns In Rio Grande Do Sul State, Brazil, Karise Fernanda Nogara, Marcos Busanello, Ione Maria Pereira Haygert-Velho, Maity Zopollatto, Karen Dal Magro Frigeri, Paulo Sergio Goes Almeida
Turkish Journal of Veterinary & Animal Sciences
Studies with compost bedded pack dairy barn system (CBDB) are still recent in Brazil. Thus, we used principal component and canonical correlation analysis to characterize and verify the relationship between compost bedded variables (CB) and bulk tank milk variables (BTM). Data are from 8 dairy farms comprising August to October 2018, in the northwest region of Rio Grande do Sul state, Brazil. Results indicated a heterogeneous BTM composition and CB management among dairy farms, besides a strong relationship between the two sets of variables (1st pair, rc = 0.972; p = 0.0253). Linear combination of CB variables explained 31.2% of …
Effects Of Age At Feedlot Entry On Performance, Carcass Characteristics, And Beef Qualitytraits Of Holstein Friesian Bulls Reared In High Altitude Of Eastern Turkey, Veysel Fati̇h Özdemi̇r, Mete Yanar
Effects Of Age At Feedlot Entry On Performance, Carcass Characteristics, And Beef Qualitytraits Of Holstein Friesian Bulls Reared In High Altitude Of Eastern Turkey, Veysel Fati̇h Özdemi̇r, Mete Yanar
Turkish Journal of Veterinary & Animal Sciences
The objective of this research was to determine the effects of different initial fattening ages on the fattening performance, carcass features, and meat quality traits of Holstein Friesian bulls. A total of 24 Holstein-Friesian intact males were used in the study. The bulls were allocated to the initial fattening age groups named as Young Group (8-10 months old) (YG), Middle Aged Group (12-14 months old) (MAG) and Older Group (15-17 months old) (OG) and then placed in the feedlot based on three age groups at feedlot entry. The data that has normal distribution were analysed by using the LSMM in …
In Vitro Gas Production And Fatty Acids Biohydrogenation Of Diets Containing Different Unsaturated Fatty Acids Sources Plus Crude Glycerin, Arturo Samuel Gomez Insuasti, Yury Tatiana Granja-Salcedo, Julian Andres Castillo Vargas, Juliana Duarte Messana, Ana Paula De Oliveira Sader, Telma Teresinha Berchielli
In Vitro Gas Production And Fatty Acids Biohydrogenation Of Diets Containing Different Unsaturated Fatty Acids Sources Plus Crude Glycerin, Arturo Samuel Gomez Insuasti, Yury Tatiana Granja-Salcedo, Julian Andres Castillo Vargas, Juliana Duarte Messana, Ana Paula De Oliveira Sader, Telma Teresinha Berchielli
Turkish Journal of Veterinary & Animal Sciences
An in vitro trial was conducted to evaluate the effects of different unsaturated fatty acids (UFA) sources plus crude glycerin (CGL) on gas production and rumen biohydrogenation (RBH). Incubated diet corresponded to diets containing corn silage (30%) and concentrate (70%) composed of corn, urea, mineral salts, CGL, and different UFA sources as follows: no additional fat (NAF), rumen protected fat (RPF), soybean oil, linoleic acid (LA) or alpha-linolenic acid (LN). Methane concentrations in LA and LN were lower compared to NAF (p < 0.001), but when CH4 was expressed as a proportion of total gas, NAF and RPF showed the greatest values among evaluated UFA sources (p = 0.001). 18:1 t11 concentration showed a faster increase from 0 to 1 h and a slower decrease from 1 to 36 h of incubation, irrespective of UFA source. A higher C18:1 t11 production rate was observed from 1 h to 5 h of incubation, where LA and LN have higher values compared to NAF and RPF diets (p < 0.001). Diets with a high content of LA may be efficient as a nutritional approach to reduce methane production and RBH, resulting in positive effects on vaccenic acid concentrations.
Determination Of Mucopolysaccharidosis Iiid In Some Goat Breeds, Yasemi̇n Gedi̇k, Orhan Kavuncu
Determination Of Mucopolysaccharidosis Iiid In Some Goat Breeds, Yasemi̇n Gedi̇k, Orhan Kavuncu
Turkish Journal of Veterinary & Animal Sciences
Mucopolysaccharidosis IIID (MPS IIID) or Sanfilippo D syndrome is an inherited lysosomal storage disease and caused by a deficiency of the N-acetylglucosamine-6-sulfatase activity, which involves in the catabolism of heparan sulfate. In addition to humans, canine, feline and murine, goats have been reported as possessing this lysosomal storage disease. The molecular defect in the MPS IIID goat has been previously identified. It has been observed that a molecular base for this defect is a nonsense mutation at nucleotide 322 (C→T) results in the change of the arginine codon to a stop codon. This mutation is not only to be related …
Autoimmunity In Psoriatic Arthritis: Pathophysiological And Clinical Aspects, Hakan Emmungi̇l, Ufuk İlgen, Rafi̇ Haner Di̇reskeneli̇
Autoimmunity In Psoriatic Arthritis: Pathophysiological And Clinical Aspects, Hakan Emmungi̇l, Ufuk İlgen, Rafi̇ Haner Di̇reskeneli̇
Turkish Journal of Medical Sciences
Psoriatic arthritis (PsA) is an underdiagnosed entity with a broad impact on the quality of life. Although the pathogenesis is largely unknown, autoimmune footprints of the inflammation in PsA have increasingly been recognized. Most of the genetic variation predisposing to PsA is mapped to the class I major histocompatibility complex (MHC) region and shared by a variety of autoimmune diseases. Polymorphisms in the genes IL12B, IL23R, IL13, TNIP1, TRAF3IP2, TYK2, and many others explain the nonHLA genetic risk with little known functional consequences. Entheseal and synovial cellular infiltrate with oligoclonal CD8+ T cells and occasional germinal centers, loss of regulatory …
Preferences Of Inflammatory Arthritis Patients For Biological Disease-Modifyingantirheumatic Drugs In The First 100 Days Of The Covid-19 Pandemic, Umut Kalyoncu, Yavuz Pehli̇van, Servet Akar, Ti̇muçi̇n Kaşi̇foğlu, Gezmi̇ş Ki̇myon, Ömer Karadağ, Hüseyi̇n Edi̇z Dalkiliç, Ali̇ İhsan Ertenli̇, Levent Kiliç, Emi̇ne Duygu Ersözlü, Cemal Bes, Hakan Emmungi̇l, Ridvan Mercan, Eli̇f Edi̇boğlu, Ni̇lüfer Alpay Kanitez
Preferences Of Inflammatory Arthritis Patients For Biological Disease-Modifyingantirheumatic Drugs In The First 100 Days Of The Covid-19 Pandemic, Umut Kalyoncu, Yavuz Pehli̇van, Servet Akar, Ti̇muçi̇n Kaşi̇foğlu, Gezmi̇ş Ki̇myon, Ömer Karadağ, Hüseyi̇n Edi̇z Dalkiliç, Ali̇ İhsan Ertenli̇, Levent Kiliç, Emi̇ne Duygu Ersözlü, Cemal Bes, Hakan Emmungi̇l, Ridvan Mercan, Eli̇f Edi̇boğlu, Ni̇lüfer Alpay Kanitez
Turkish Journal of Medical Sciences
Background/aim: To evaluate treatment adherence and predictors of drug discontinuation among patients with inflammatory arthritis receiving bDMARDs within the first 100 days after the announcement of the COVID-19 pandemic. Materials and methods: A total of 1871 patients recorded in TReasure registry for whom advanced therapy was prescribed for rheumatoid arthritis (RA) or spondyloarthritis (SpA) within the 3 months (6-9 months for rituximab) before the declaration of COVID-19 pandemic were evaluated, and 1394 (74.5%) responded to the phone survey. Patients' data regarding demographic, clinical characteristics and disease activity before the pandemic were recorded. The patients were inquired about the diagnosis of …
The Comparison Of Favipiravir And Lopinavir/Ritonavir Combination In Covid-19treatment, Hali̇t Çinarka, Gülşah Günlüoğlu, Mustafa Çörtük, Si̇bel Yurt, Murat Kiyik, Ayşe Fi̇li̇z Koşar, Eli̇f Tanriverdi̇, Meli̇h Akay Arslan, Kürşad Nuri̇ Baydi̇li̇, Aysu Si̇nem Koç, Sedat Altin, Erdoğan Çeti̇nkaya
The Comparison Of Favipiravir And Lopinavir/Ritonavir Combination In Covid-19treatment, Hali̇t Çinarka, Gülşah Günlüoğlu, Mustafa Çörtük, Si̇bel Yurt, Murat Kiyik, Ayşe Fi̇li̇z Koşar, Eli̇f Tanriverdi̇, Meli̇h Akay Arslan, Kürşad Nuri̇ Baydi̇li̇, Aysu Si̇nem Koç, Sedat Altin, Erdoğan Çeti̇nkaya
Turkish Journal of Medical Sciences
Background/aim: SARS-CoV-2, a ribonucleic acid coronavirus, rapidly spread worldwide within a short timeframe. Although different antiviral, antiinflammatory, and immunomodulatory drugs are used, current evidence is insufficient as to which drug is more efficient. Our study compared favipiravir and lopinavir/ritonavir (LPV/RTV) therapies in inpatient care for coronavirus disease 2019 (COVID-19) pneumonia. Materials and methods: Demographic data, test results, treatments, and latest status of patients receiving inpatient COVID-19 pneumonia therapy were recorded. The initial favipiravir and LPV/RTV receiving groups were compared regarding the need for intensive care units (ICU) and mortality. Logistic regression analysis was performed by including variables showing significant differences …
Impact Of Covid-19 On Serum Melatonin Levels And Sleep Parameters In Children, Özlem Yayici Köken, Pembe Gültutan, Merve Si̇bel Güngören, Gülsüm İclal Bayhan, Deni̇z Yilmaz, Esra Gürkaş, Hami̇t Özyürek, Ayşegül Neşe Çitak Kurt
Impact Of Covid-19 On Serum Melatonin Levels And Sleep Parameters In Children, Özlem Yayici Köken, Pembe Gültutan, Merve Si̇bel Güngören, Gülsüm İclal Bayhan, Deni̇z Yilmaz, Esra Gürkaş, Hami̇t Özyürek, Ayşegül Neşe Çitak Kurt
Turkish Journal of Medical Sciences
Background/aim: This study aimed to analyze the serum melatonin levels and changes in sleep patterns in pediatric patients with coronavirus disease 2019 (COVID-19). Materials and methods: This study was designed as a descriptive, cross-sectional study. Serum melatonin levels and sleep parameters of children with the diagnosis of COVID-19 who had mild and moderate disease (i.e., COVID-19 group) were compared with those of children admitted with non-COVID-19 nonspecific upper respiratory tract infection (i.e., control group). The sleep disturbance scale for children (SDSC) questionnaire was applied to the participants' primary caregivers to analyze their sleep patterns at present and six months before …
Long-Term Proton Pump Inhibitor Use Is A Risk Factor For Mortality In Patientshospitalized For Covid-19, Ahmet Yozgat, Benan Kasapoğlu, Güray Can, Alpaslan Tanoğlu, Yusuf Serdar Saki̇n, Kadi̇r Serkan Yalçin, Müjgan Gürler, Mustafa Kaplan, Mehmet Göktürk Kaban, Mehmet Kirsoy, Umut Kara, Murat Keki̇lli̇
Long-Term Proton Pump Inhibitor Use Is A Risk Factor For Mortality In Patientshospitalized For Covid-19, Ahmet Yozgat, Benan Kasapoğlu, Güray Can, Alpaslan Tanoğlu, Yusuf Serdar Saki̇n, Kadi̇r Serkan Yalçin, Müjgan Gürler, Mustafa Kaplan, Mehmet Göktürk Kaban, Mehmet Kirsoy, Umut Kara, Murat Keki̇lli̇
Turkish Journal of Medical Sciences
Background and aim: The aim of this study is to evaluate whether the long-term (≥4 weeks) use of proton pump inhibitors (PPIs) is a risk factor for intubation requirement and mortality in patients hospitalized for COVID-19. Materials and methods: In this multicentric retrospective study, a total of 382 adult patients (≥18 years of age) with confirmed COVID-19 who were hospitalized for treatment were enrolled. The patients were divided into two groups according to the periods during which they used PPIs: the first group included patients who were not on PPI treatment, and the second group included those who have used …
Nutritional Status In Patients With Neuro-Behçet's Disease, Seyda Erdoğan, Mi̇ne Hayri̇ye Sorgun, Müge Kuzu Kumcu, Mustafa Aykut Kural, Sefer Rzayev, Canan Yücesan
Nutritional Status In Patients With Neuro-Behçet's Disease, Seyda Erdoğan, Mi̇ne Hayri̇ye Sorgun, Müge Kuzu Kumcu, Mustafa Aykut Kural, Sefer Rzayev, Canan Yücesan
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to assess the nutritional status and risk factors for malnutrition in Behçet's disease (BD) and neuro-Behçet's disease (NBD) patients. Materials and methods: Medical recordings of 74 patients with BD without neurological involvement (BDWoNI), 72 patients with NBD, and 50 patients with other diseases (carpal tunnel syndrome or lumbar discopathy) were analyzed retrospectively. The serum analyses were performed in the inactive period of disease. Chronic malnutrition was defined as low levels of serum albumin (
Risk Of Tuberculosis Is Increased In Behçet's Disease Compared To Other Rheumatologicaldisorders After Anti-Tnf∝ Treatments: A Case Series And Review Of The Literature, Ümmügülsüm Gazel, Derya Kocakaya, İrem Hi̇cret Topçu, Hakan Ömer Karataş, Murat Karabacak, Mehmet Pami̇r Atagündüz, Güzi̇de Nevsun İnanç, Fatma Ali̇baz Öner, Rafi̇ Haner Di̇reskeneli̇
Risk Of Tuberculosis Is Increased In Behçet's Disease Compared To Other Rheumatologicaldisorders After Anti-Tnf∝ Treatments: A Case Series And Review Of The Literature, Ümmügülsüm Gazel, Derya Kocakaya, İrem Hi̇cret Topçu, Hakan Ömer Karataş, Murat Karabacak, Mehmet Pami̇r Atagündüz, Güzi̇de Nevsun İnanç, Fatma Ali̇baz Öner, Rafi̇ Haner Di̇reskeneli̇
Turkish Journal of Medical Sciences
Background/aim: Tumor necrosis factor-alfa (TNF-a) antagonists are extensively utilized in the treatment of inflammatory rheumatic diseases and also shown to be effective in Behçet's disease (BD) patients with major organ involvement. In this study, we aimed to reevaluate the incidence of tuberculosis (TB) infection after anti-TNFa treatments and to reveal the risk of TB in BD. Methods: Data of patients who received anti-TNFa treatment between 2005 and 2018 were assessed retrospectively. Demographic features, TNF-a antagonist type/treatment time, tuberculosis skin test (TST) and QuantiFERON results, isoniazid prophylaxis status, and concomitant corticosteroid (CS) treatments were collected. Results: A total of 1277 (male/female …
Appendectomy History Is Associated With Severe Disease And Colchicine Resistance In Adultfamilial Mediterranean Fever Patients, Erdal Bodakçi̇, Nazi̇fe Şule Yaşar Bi̇lge, Nuh Ataş, Berkan Armağan, Hasan Satiş, Alper Sari, Reyhan Bi̇li̇ci̇ Salman, Gözde Kübra Yardimci, Hakan Babaoğlu, Levent Kiliç, Mehmet Aki̇f Öztürk, Berna Göker, Şemi̇nur Haznedaroğlu, Umut Kalyoncu, Abdurrahman Tufan
Appendectomy History Is Associated With Severe Disease And Colchicine Resistance In Adultfamilial Mediterranean Fever Patients, Erdal Bodakçi̇, Nazi̇fe Şule Yaşar Bi̇lge, Nuh Ataş, Berkan Armağan, Hasan Satiş, Alper Sari, Reyhan Bi̇li̇ci̇ Salman, Gözde Kübra Yardimci, Hakan Babaoğlu, Levent Kiliç, Mehmet Aki̇f Öztürk, Berna Göker, Şemi̇nur Haznedaroğlu, Umut Kalyoncu, Abdurrahman Tufan
Turkish Journal of Medical Sciences
Background/aim: Peritonitis attacks of Familial Mediterranean Fever (FMF) usually requires emergency medical admissions and it's hard to distinguish a typical abdominal attack from surgical causes of acute abdomen. Therefore, history of abdominal surgery, particularly appendectomy, is very common in patients with FMF. However, history of appendectomy might also give some clues about the course of FMF in the adulthood. This study was to determine whether the history of appendectomy help to anticipate disease course of FMF in the adulthood. Materials and methods: All patients recruited from FMF in Central Anatolia (FiCA) cohort, comprising 971 adult subjects. All patients fulfilled the …
Decreased Exercise Capacity, Strength, Physical Activity Level And Quality Of Life In Adultpatients With Familial Mediterranean Fever, Nurten Gi̇zem Tore, Fulden Sari̇, Devri̇m Can Saraç, Seli̇n Bayram, Hasan Satiş, Hazan Karadeni̇z, Abdurrahman Tufan, Deran Oskay
Decreased Exercise Capacity, Strength, Physical Activity Level And Quality Of Life In Adultpatients With Familial Mediterranean Fever, Nurten Gi̇zem Tore, Fulden Sari̇, Devri̇m Can Saraç, Seli̇n Bayram, Hasan Satiş, Hazan Karadeni̇z, Abdurrahman Tufan, Deran Oskay
Turkish Journal of Medical Sciences
Background: Familial Mediterranean fever (FMF) is a systemic autoinflammatory disease that causes recurrent attacks of fever, polyserositis, arthritis or skin eruptions, resulting in pain in the abdomen, muscles, joints and chest. All of these might lead to a reduction in exercise capacity, muscle strength, physical activity level (PAL) and quality of life (QoL). Therefore, assesment of these parameters are important. The aim of this study was to assess exercise capacity, muscle strength, PAL, and QoL in patients with FMF as compared to controls. Materials and methods: A total of 40 subjects with FMF and 36 healthy control subjects participated in …
Factors Affecting Relapse In Patients With Granulomatosis Polyangiitis: A Single-Centerretrospective Cohort Study, Müge Aydin Tufan, Ni̇han Tekkarişmaz, Ahmet Eftal Yücel
Factors Affecting Relapse In Patients With Granulomatosis Polyangiitis: A Single-Centerretrospective Cohort Study, Müge Aydin Tufan, Ni̇han Tekkarişmaz, Ahmet Eftal Yücel
Turkish Journal of Medical Sciences
Background and aim: This study aimed to determine the frequency of relapse, the risk factors for relapse, and the correlation of relapse with immunosuppressive regimens in patients with granulomatosis polyangiitis (GPA). Materials and methods: The demographic characteristics, the clinical, laboratory, and radiological findings, the immunosuppressive treatment regimens, and the remission and relapse rates of 50 patients with GPA were obtained retrospectively from medical records. Results: The mean relapse-free survival rates at years 1, 3, and 5 were 82%, 60%, and 50%, respectively. Increased relapse rates were observed in patients who had cavitary lung lesions (52.2% vs. 22.2%, p = 0.04) …
The Relationship Of Carotid Intima-Media Thickness With Anthropometric And Metabolicparameters In Patients With Classic Congenital Adrenal Hyperplasia, Hale Ünver Tuhan, Tülay Öztürk Atasoy, Gönül Çatli, Sezer Acar, Ayhan Abaci, Tuğba Üçüncü Egeli̇, Korcan Demi̇r, Penbe Şule Can, Handan Güleryüz, Bumi̇n Nuri̇ Dündar, Ece Böber
The Relationship Of Carotid Intima-Media Thickness With Anthropometric And Metabolicparameters In Patients With Classic Congenital Adrenal Hyperplasia, Hale Ünver Tuhan, Tülay Öztürk Atasoy, Gönül Çatli, Sezer Acar, Ayhan Abaci, Tuğba Üçüncü Egeli̇, Korcan Demi̇r, Penbe Şule Can, Handan Güleryüz, Bumi̇n Nuri̇ Dündar, Ece Böber
Turkish Journal of Medical Sciences
Background/aim: We aimed to determine the presence of subclinical atherosclerosis using carotid intima-media thickness (CIMT) and biochemical parameters in children and adolescents with congenital adrenal hyperplasia (CAH). Materials and methods: Thirty-four patients with classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency on regular glucocorticoid treatment for ≥3 years and 31 healthy subjects were included in the study. The patients were divided into two groups according to the degree of control of the clinic, laboratory, and radiological parameters as a) "uncontrolled" [n= 22; with increased height velocity (HV) standard deviation score (SDS) (≥2 SDS), advanced bone age, serum 17-OH progesterone 0.05]. …
The Use Of High-Flow Nasal Oxygen Vs. Standard Oxygen Therapy In Hematologicalmalignancy Patients With Acute Respiratory Failure In Hematology Wards, Ni̇lgün Özlem Alpteki̇noğlu Mendi̇l, Şahi̇n Temel, Recep Ci̇van Yüksel, Kürşat Gündoğan, Bülent Eser, Leylagül Kaynar, Murat Sungur
The Use Of High-Flow Nasal Oxygen Vs. Standard Oxygen Therapy In Hematologicalmalignancy Patients With Acute Respiratory Failure In Hematology Wards, Ni̇lgün Özlem Alpteki̇noğlu Mendi̇l, Şahi̇n Temel, Recep Ci̇van Yüksel, Kürşat Gündoğan, Bülent Eser, Leylagül Kaynar, Murat Sungur
Turkish Journal of Medical Sciences
Background/aim: High flow nasal cannula (HFNC) was mostly used in intensive care units (ICUs) with few studies in other departments. We hypothesized that HFNC applied at wards is beneficial for acute respiratory failure in hematological malignancy patients. Materials and methods: The study is a single center, randomized controlled study. Inclusion criteria were hypoxemic respiratory failure and hematological malignancy. Patients were randomized to either venturi mask/nasal cannula oxygen treatment or HFNC. Results: One hundred patients were included in the study. Median age was 58.5 (18-86) years and APACHE II score was 17 (5-29). HFNC group was 51 patients and the oxygen …
Investigating Differential Mirna Expression Profiling Using Serum And Urine Specimensfor Detecting Potential Biomarkers For Early Prostate Cancer Diagnosis, Sevde Hasanoğlu, Beyza Servet Göncü, Emrah Yücesan, Sezen Atasoy, Yunus Kayali, Nur Özten Kandaş
Investigating Differential Mirna Expression Profiling Using Serum And Urine Specimensfor Detecting Potential Biomarkers For Early Prostate Cancer Diagnosis, Sevde Hasanoğlu, Beyza Servet Göncü, Emrah Yücesan, Sezen Atasoy, Yunus Kayali, Nur Özten Kandaş
Turkish Journal of Medical Sciences
Background/aim: MicroRNAs (miRNAs) are known up-to-date candidate biomarkers for several diseases. In addition, obtaining miRNA from different body fluids such as serum, plasma, saliva, and urine is relatively easy to handle. Herein we aimed to detect miRNAs as biomarkers for early stage prostate cancer (PC). For this purpose, we used urine and serum samples to detect any significant differences in miRNA profiles between patients and healthy controls. Materials and methods: Total ribonucleic acid (RNA) in urine and serum samples were isolated from eight untreated PC patients, thirty healthy individuals were screened for miRNA profile, and candidate miRNAs were validated. Whole …
20-Year Experience On Prenatal Diagnosis In A Reference University Medical Geneticscenter In Turkey, Mehmet Burak Durmaz, Hi̇lmi̇ Bolat, Zehra Cengi̇si̇z, Fuat Akercan, Tuba Sözen Türk, Erhan Pariltay, Asli Ece Solmaz, Mert Kazandi, Emi̇n Karaca, Asude Durmaz, Ayça Aykut, Sermet Sağol, Haluk Akin, Feri̇ştah Ferda Özkinay, Muhsi̇n Özgür Çoğulu
20-Year Experience On Prenatal Diagnosis In A Reference University Medical Geneticscenter In Turkey, Mehmet Burak Durmaz, Hi̇lmi̇ Bolat, Zehra Cengi̇si̇z, Fuat Akercan, Tuba Sözen Türk, Erhan Pariltay, Asli Ece Solmaz, Mert Kazandi, Emi̇n Karaca, Asude Durmaz, Ayça Aykut, Sermet Sağol, Haluk Akin, Feri̇ştah Ferda Özkinay, Muhsi̇n Özgür Çoğulu
Turkish Journal of Medical Sciences
Background/aim: Although cutting edge procedures such as cell-free fetal DNA isolation from maternal blood are now available, invasive prenatal tests are still being used extensively for prenatal diagnosis. The study aims to evaluate the demographic data, indications, and cytogenetic results of 9297 results of patients who underwent prenatal invasive testing for genetic analysis that were referred for the last 20 years in a University Medical Genetics Center. Materials and methods: The records of 8363 amniocenteses, 626 chorionic villus, and 308 cordocenteses samples were retrospectively evaluated and analyzed regarding referral reasons, indications and their cytogenetic results. The total numbers and the …
Rituximab Treatment For Difficult-To-Treat Nephrotic Syndrome In Children:A Multicenter, Retrospective Study, Mehmet Taşdemi̇r, Nur Canpolat, Nurdan Yildiz, Gül Özçeli̇k, Meryem Benzer, Seha Kami̇l Saygili, Emi̇ne Neşe Özkayin, Özde Ni̇sa Türkkan, Ayşe Balat, Cengi̇z Candan, Mehtap Çelakil, Sevgi̇ Yavuz, Nurver Akinci, Ni̇lüfer Göknar, Ci̇hangi̇r Akgün
Rituximab Treatment For Difficult-To-Treat Nephrotic Syndrome In Children:A Multicenter, Retrospective Study, Mehmet Taşdemi̇r, Nur Canpolat, Nurdan Yildiz, Gül Özçeli̇k, Meryem Benzer, Seha Kami̇l Saygili, Emi̇ne Neşe Özkayin, Özde Ni̇sa Türkkan, Ayşe Balat, Cengi̇z Candan, Mehtap Çelakil, Sevgi̇ Yavuz, Nurver Akinci, Ni̇lüfer Göknar, Ci̇hangi̇r Akgün
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the efficacy of rituximab in children with difficult-to-treat nephrotic syndrome, considering the type of disease (steroid-sensitive or -resistant) and the dosing regimen. Materials and methods: This multicenter retrospective study enrolled children with difficult-to-treat nephrotic syndrome on rituximab treatment from 13 centers. The patients were classified based on low (single dose of 375 mg/m2 ) or high (2-4 doses of 375 mg/m2 ) initial dose of rituximab and the steroid response. Clinical outcomes were compared. Results: Data from 42 children [20 steroid-sensitive (frequent relapsing / steroid-dependent) and 22 steroid-resistant nephrotic syndrome, aged 1.9-17.3 years] were …
Investigation Of The Relationship Between Immune Checkpoints And Mismatch Repairdeficiency In Recurrent And Nonrecurrent Glioblastoma, Emel Çakir, İsmai̇l Sayğin, Mustafa Emre Erci̇n
Investigation Of The Relationship Between Immune Checkpoints And Mismatch Repairdeficiency In Recurrent And Nonrecurrent Glioblastoma, Emel Çakir, İsmai̇l Sayğin, Mustafa Emre Erci̇n
Turkish Journal of Medical Sciences
Background/aim: Microsatellite instability tests and programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) in the immune checkpoint pathway are the tests that determine who will benefit from immune checkpoint inhibitor therapy. We aimed to show the expression of DNA mismatch repair proteins and PD-1/PD-L1 molecules that inhibit immune checkpoints, to explain the relationship between them, and to demonstrate their predictive role in recurrent and nonrecurrent glioblastoma. Materials and methods: We analyzed 27 recurrent and 47 nonrecurrent cases at our archive. We performed immunohistochemical analysis to determine expressions of PD-1, PD-L1, and mismatch repair proteins in glioblastoma. We evaluated the relationship …
Reference Values For T And B Lymphocyte Subpopulations In Turkish Children And Adults, Özge Besci̇, Di̇lek Başer, İsmai̇l Öğülür, Ayşe Cansu Berberoğlu, Ayça Kiykim, Tolga Besci̇, Asim Leblebi̇ci̇, Hülya Elli̇dokuz, Perran Boran, Eren Özek, Goncagül Haklar, Ahmet Oğuzhan Özen, Safa Bariş, Eli̇f Aydiner
Reference Values For T And B Lymphocyte Subpopulations In Turkish Children And Adults, Özge Besci̇, Di̇lek Başer, İsmai̇l Öğülür, Ayşe Cansu Berberoğlu, Ayça Kiykim, Tolga Besci̇, Asim Leblebi̇ci̇, Hülya Elli̇dokuz, Perran Boran, Eren Özek, Goncagül Haklar, Ahmet Oğuzhan Özen, Safa Bariş, Eli̇f Aydiner
Turkish Journal of Medical Sciences
Background/aim: Established reference values are critical for the interpretation of immunologic assessments. In particular, the proportion and absolute counts of T- and B- cell subpopulations are subject to change with age and ethnicity. We aimed to establish agespecific reference values for lymphocyte subsets using updated immunophenotyping panels. Materials and methods: We studied a total of 297 healthy Turkish subjects aged 0 to 50 years, stratified into major age brackets in a cluster factor of 10 per age-group. The predetermined age intervals contained randomly allocated participants enrolled over a period of 6 months, who were homogenously distributed by sex. We analyzed …
Prognostic Value Of Oxygen Saturation And Heart Rate During A Six-Minute Walk Test Inpediatric Pulmonary Hypertension, Vi̇ldan Atasayan, Fatma Canbeyli̇, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Bülent Çeli̇k, Serdar Kula
Prognostic Value Of Oxygen Saturation And Heart Rate During A Six-Minute Walk Test Inpediatric Pulmonary Hypertension, Vi̇ldan Atasayan, Fatma Canbeyli̇, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Bülent Çeli̇k, Serdar Kula
Turkish Journal of Medical Sciences
Background/aim: To evaluate the pre and post-treatment heart rate and oxygen (O2 ) saturation values measured before, during and after 6MWT in children who received PAH-specific treatment and to determine the effect of these variables on prognosis. Materials and methods: This retrospective study included 29 patients who were diagnosed as PAH and treated. The transcutaneous O2 saturationand heart rate levels were recorded before the test: baseline (Sat0, HR0), at the end of the test: exercise (Sat1, HR1) and 5 min after the test: recovery (Sat2, HR2). The increase in heart rate was defined as HR1-HR0 and the decrease in saturation …