Medicine and Health Sciences Commons^™

A Voice-Based Automated System For Ptsd Screening And Monitoring, Roger Xu, Gang Mei, Guangfan Zhang, Pan Gao, Timothy Judkins, Michael Cannizzaro, Jiang Li, James D. Westwood (Ed.), Susan W. Westwood (Ed.), Li Felländer-Tsai (Ed.), Randy S. Haluck (Ed.), Richard A. Robb (Ed.), Steven Senger (Ed.), Kirby G. Vosburgh (Ed.)

Electrical & Computer Engineering Faculty Publications

Comprehensive evaluation of PTSD includes diagnostic interviews, self-report testing, and physiological reactivity measures. It is often difficult and costly to diagnose PTSD due to patient access and the variability in symptoms presented. Additionally, potential patients are often reluctant to seek help due to the stigma associated with the disorder. A voice-based automated system that is able to remotely screen individuals at high risk for PTSD and monitor their symptoms during treatment has the potential to make great strides in alleviating the barriers to cost effective PTSD assessment and progress monitoring. In this paper we present a voice-based automated Tele-PTSD Monitor …

In Vitro Antimicrobial Effect Of A Cold Plasma Jet Against Enterococcus Faecalis Biofilms, Chunqi Jiang, Christoph Schaudinn, David E. Jaramillo, Paul Webster, J. William Costerton

Bioelectrics Publications

The hypothesis that a cold plasma jet has the antimicrobial effect against Enterococcus faecalis biofilms was tested in vitro. 27 hydroxyapatite discs were incubated with E. faecalis for six days to form a monoculture biofilm on the disc surface. The prepared substrata were divided into three groups: the negative control, the positive control (5.25% NaOCl solution), and the plasma treatment group. Resultant colony-forming unit counts were associated with observations of bacterial cell morphology changes using scanning electron microscopy (SEM). Treatment of E. faecalis biofilm with the plasma and 5.25% NaOCl for 5min resulted in 93.1% and 90.0% kill (P < 0.0001), respectively. SEM detected that nearly no intact bacteria were discernible for the plasmaexposed HA disc surfaces. The demonstrated bactericidal effect of the plasma with direct surface contact may be due to the enhanced oxidation by the locally produced reactive plasma species.

Drinking Buddies And Their Prospective Influence On Alcohol Outcomes: Alcohol Expectancies As A Mediator, Cathy Lau-Barraco, Abbly L. Braitman, Kenneth E. Leonard, Miguel Padilla

Psychology Faculty Publications

The process by which peers or the social network influence individual alcohol use, particularly among adults, remains a necessary area of research. The purpose of the present study was to examine the longitudinal influence of "drinking buddies" on alcohol outcomes (i.e., alcohol use, heavy drinking, and alcohol-related problems) as mediated by alcohol expectancies of social facilitation. Participants were 1347 (men = 660, women = 687) newly married individuals recruited from the community. They were assessed at the time of marriage and through the fourth wedding anniversary. Longitudinal mediation across time was evaluated using latent growth modeling. Overall, the prospective association …

Brain-Computer Interfaces In Medicine, Jerry J. Shih, Dean J. Krusienski, Johnathan R. Wolpaw

Electrical & Computer Engineering Faculty Publications

Brain-computer interfaces (BCIs) acquire brain signals, analyze them, and translate them into commands that are relayed to output devices that carry out desired actions. BCIs do not use normal neuromuscular output pathways. The main goal of BCI is to replace or restore useful function to people disabled by neuromuscular disorders such as amyotrophic lateral sclerosis, cerebral palsy, stroke, or spinal cord injury. From initial demonstrations of electroenceph-alography-based spelling and single-neuron-based device control, researchers have gone on to use electroenceph-alographic, intracortical, electrocorticographic, and other brain signals for increasingly complex control of cursors, robotic arms, prostheses, wheelchairs, and other devices. Brain-computer interfaces …

Signals From Intraventricular Depth Electrodes Can Control A Brain-Computer Interface, Jerry J. Shih, Dean J. Krusienski

Electrical & Computer Engineering Faculty Publications

A Brain-Computer Interface (BCI) is a device that enables severely disabled people to communicate and interact with their environments using their brain waves. Most research investigating BCI in humans have used scalp-recorded electroencephalography (EEG). We have recently demonstrated that signals from intracranial electrocorticography (ECoG) and stereotactic depth electrodes (SDE) in the hippocampus can be used to control a BCI P300 Speller paradigm. We report a case in which stereotactic depth electrodes positioned in the ventricle were able to obtain viable signals for a BCI. Our results demonstrate that event-related potentials from intraventricular electrodes can be used to reliably control the …

Physical Activity: The Forgotten Tool For Type 2 Diabetes Management, Sheri R. Colberg

Human Movement Studies & Special Education Faculty Publications

Individuals who are currently sedentary, unfit, or overweight can benefit metabolically from simply taking breaks from sitting. Since avoidance of sedentary behavior appears to have a large impact on glycemic management, all individuals with type 2 diabetes should be encouraged to minimally engage in greater daily movement to better manage their diabetes and body weight. In addition, engaging in physical activity of any intensity (including low-intensity ones) likely positively impacts insulin action and blood glucose control acutely. Moreover, as long as total caloric expenditure during exercise is matched (i.e., total exercise dose), daily exercise may be done every other day …

A Preliminary Study On The Potential Of Manuka Honey And Platelet-Rich Plasma In Wound Healing, Scott A. Sell, Patricia S. Wolfe, Andrew J. Spence, Isaac A. Rodriguez, Jennifer M. Mccoll, Rebecca L. Petrella, Koyal Garg, Jeffery J. Ericksen, Gary L. Bowlin

Ellmer School of Nursing Faculty Publications

Aim. The purpose of this study was to determine the in vitro response of cells critical to the wound healing process in culture media supplemented with a lyophilized preparation rich in growth factors (PRGF) and Manuka honey. Materials and Methods. This study utilized cell culture media supplemented with PRGF, as well as whole Manuka honey and the medical-grade Medihoney (MH), a Manuka honey product. The response of human fibroblasts (hDF), macrophages, and endothelial cells (hPMEC) was evaluated, with respect to cell proliferation, chemotaxis, collagen matrix production, and angiogenic potential, when subjected to culture with media containing PRGF, MH, Manuka honey, …

Falls And Physical Activity In Persons With Multiple Sclerosis, J. J. Sosnoff, B. M. Sandroff, J. H. Pula, S. M. Morrison, R. W. Motl

Rehabilitation Sciences Faculty Publications

Objectives. To examine the association between fall history and physical activity using an objective measure of physical activity (i.e., accelerometry) in persons with multiple sclerosis.

Design. A community-based sample of 75 ambulatory persons with multiple sclerosis volunteered for the investigation. Participants self-reported fall history in the last year, underwent a neurological exam to determine Expanded Disability Status Scale (EDSS) score, and wore an accelerometer around the waist for 7 consecutive days to determine physical activity.

Results. Overall, 37 persons (49.3% of the sample) reported falling in the last year with 28 of the 37 falling more than once. Persons who …

Intimate Partner Physical Violence Against Women In Saudi Arabian Primary Healthcare Clinics, Halah M. Eldoseri

Health Services Research Dissertations

Intimate partner violence against women (IPPVAW) is a serious public health concern. The Ecological Model provides a model to study several factors associated with IPPVAW. In Saudi Arabia, studies addressing IPPVAW are limited and do not cover the various aspects of the problem. The purpose of this study was to investigate the various factors associated with IPPVAW at the personal, interpersonal, community and societal levels. Methods: 200 ever-married women attending six PHC in Jeddah, Saudi Arabia were recruited via convenient sampling method. Women were interviewed on factors related to IPPVAW using an adapted version of WHO survey for violence against …

Transition From High School To Associate Degree Nursing Education: A Qualitative Study, Kathy Jessee Mitchell

Educational Leadership & Workforce Development Theses & Dissertations

Nursing is facing a critical shortage and retention of nursing students is of paramount importance. Much research has been completed related to retention in nursing education and student success, but there is very little in current literature related to issues associated with the transition from high school to associate degree nursing (ADN) education. The purpose of this study was to explore this phenomenon through qualitative research involving ADN students who entered the nursing programs immediately after graduation from high school. This qualitative study involved students from a rural associate degree program. The intent was to provide a better understanding of …

Effects Of Low Temperature Atmospheric Pressure Plasma On Tooth Whitening, Denise Michelle Claiborne

Dental Hygiene Theses & Dissertations

Low temperature atmospheric pressure plasma (LT APP) is a novel science being studied as an alternative light source to enhance tooth whitening. The safety and effectiveness of LTAPP has not been established therefore; the purpose of this study was to determine if LTAPP along with H₂O₂ gel would safely and effectively accelerate the tooth whitening process, in terms of lightness and temperature. Two treatment groups were utilized: 36% H₂O₂ gel only and 36% H₂O₂ gel plus LT APP. Control group received no treatment. Experimental teeth were exposed to LT APP at …

Community College Student Learning In Phlebotomy Preceptor-Led Clinical Internship, Susan E. Phelan

Educational Leadership & Workforce Development Theses & Dissertations

The purpose of this study is to describe how allied health preceptor-led clinical internship improves or expands community college student learning. There is a significant gap of information in the literature related to the importance of this clinical internship experience for the learning, socialization, and professional development of allied health students in general and community college students in particular. The absence of relevant data for these internships as a situated learning experience is evident in the literature review. The majority of the allied health work force is prepared by community colleges. Therefore, community college leaders need data to make data-driven …

Use Of Optimal Control Models To Predict Treatment Time For Managing Tick-Borne Disease, Holly D. Gaff, Elsa Schaefer, Suzanne Lenhart

Biological Sciences Faculty Publications

Tick-borne diseases have been on the rise recently, and correspondingly, there is an increased interest in implementing control measures to decrease the risk. Optimal control provides an ideal tool to identify the best method for reducing risk while accounting for the associated costs. Using a previously published model, a variety of frameworks are assessed to identify the key factors influencing mitigation strategies. The level and duration of tick-reducing efforts are key metrics for understanding the successful reduction in tick-borne disease incidence. The results show that the punctuated nature of the tick's life history plays a critical role in reducing risk …

Using Modeling And Simulation To Improve Oral Health Services Delivery In Hampton Roads, Virginia, Mohammad J. Alzahrani

Health Services Research Dissertations

The purpose of this study is to examine the system performance in delivering oral health services in a public health district based on the Conceptual Framework to Measure Performance of the Public Health System (PHS). Using modeling and simulation, a predictive model based on the conceptual framework dimensions: mission, structural capacity, processes, and outcomes was developed to predict the performance of public health district in delivering oral health services.

This is a retrospective longitudinal study. The main objective of this study is to use a modeling and simulation approach to predict the performance of public health district dental clinic in …

Conditions For Empathy In Medicine: A Grounded Theory Study, Hannah Barnhill Bayne

Counseling & Human Services Theses & Dissertations

Previous research in the medical setting has credited empathy with improving treatment outcomes and patient satisfaction, though operational definitions of the concept are widely varied and indicate inconsistencies in conceptualization and subsequent assessment. The purpose of this grounded theory study was to examine the role of empathy in the medical setting. A model of conditions for empathy in medicine was developed through in-depth interviews with 21 healthcare professionals, utilizing their professional experiences and perspectives to structure the multi-level model. The seven levels of the model indicate the layers of complexity inherent in facilitating optimal empathy in medicine and add to …

Cyberknife Radiation Modeling: Effects Of Relaxed Translational And Rotational Constraints On Healthy Tissue Irradiation, Sudha Bhavaroop Potineni

Electrical & Computer Engineering Theses & Dissertations

The Cyberknife system is a robotic radio surgery instrument that is used to treat cancers in different parts of the human body. Because of its accuracy and precision, it has become one of the best radio surgery systems in the world. However, even with Cyberknife the treatment time for one session takes from 30 minutes up to 120 minutes depending on the size, shape, and position of the tumor in the human body. In this research, a solution is presented to aid in reducing this long treatment time. An algorithm is developed which simulates the amount of the healthy tissue …

Prenatal Smoking And Drinking Implications For Subsequent Child Maltreatment, Nicholas Alexander Adams

Sociology & Criminal Justice Theses & Dissertations

Prenatal smoking and drinking are very serious problems that have continued to plague society. They have multiple negative effects on the child both physically and cognitively. This study explored the relationship between prenatal abuse, i.e., prenatal smoking and prenatal drinking, and subsequent child physical abuse and official reports of child maltreatment. It was hypothesized that mothers who smoked or drank prenatally would be more likely to physically abuse their child postnatally and have official reports of child maltreatment. The sample included women participating in Wave III of the National Longitudinal Survey of Adolescent Health. N = 620 women who answered …

Plantar Pressure Distribution Differences In Physically Active Individuals With And Without Functional Ankle Instability During A Side Cut, J'Nai Pittman

Human Movement Studies & Special Education Theses & Dissertations

Context: Functional ankle instability (FAI) is a popular condition in the physically active population. There is a surplus of evidence to demonstrate how FAI decreases proprioception, balance, and overall athletic performance. However, to date there is no evidence that demonstrates how F AI correlates to alterations in plantar pressure distribution differences in a physically active population while completing athletic tasks. Objective: To assess differences in plantar pressure distributions while completing a side cut in individuals with and without FAI. Design: Observational case-control. Setting: Outdoor field turf and research laboratory. Participants: Fifty ankles from physically active individuals (FAI: age= 21.47±3.02 yrs; …

Early Diagnosis Of Pulmonary Embolism: Review And Cost-Effectiveness Analysis, Efstathios Polychronopoulos

Health Services Research Dissertations

Pulmonary embolism (PE) is a serious, life-threatening thrombotic disease, which results in considerable health and economic consequences each year for the United States. These consequences include a toll of 83,000 deaths and an economic impact between 1,5 and 5 billion. Approaches to strategy selection by physicians and other health-care specialists are based mainly upon cost, technology availability, and cultural tolerance regarding radiation exposure. The purpose of this study was to determine the most cost-effective diagnostic strategy with patients suspected of PE among several strategies currently used by examining their detection failure rates. This objective was met by (a) assessing parameter …

Treating Trauma Survivors With Neurofeedback: A Grounded Theory Study Based On The Practices Of Experienced Mental Health Professionals, Christine L. Currie

Counseling & Human Services Theses & Dissertations

Neuroscience, the mental health field, and the concept of trauma as an underlying factor in mental and physical disorders have been inextricably linked since the inception of the mental health professions. Numerous quantitative studies have indicated that neurofeedback may be effective in ameliorating trauma symptoms; however, there is a paucity of research exploring the factors that produce those positive outcomes. The purpose of this qualitative grounded theory study was to explore the factors and processes that influence treatment outcomes when neurofeedback is used with trauma survivors. Thirty interviews were completed with ten experienced mental health and neurofeedback professionals identified through …

Section Abstracts: Medical Science

Virginia Journal of Science

Abstracts of the Medical Science Section for the 89th Annual Meeting of the Virginia Academy of Science, May 25-27, 2011, University of Richmond, Richmond VA.

An Extensible Mathematical Model Of Glucose Metabolism, Caleb L. Adams

Mathematics & Statistics Theses & Dissertations

The American Diabetes Association reports that diabetes is the fifth leading cause of death by disease in the United States. An estimated 23.6 million individuals, or seven percent of the population, have diabetes. Nearly one-third are unaware that they have the disease. The total of the direct and indirect medical costs associated with diabetes in 2007 was projected to be $174 billion, or approximately one out of every ten health care dollars.

One must understand the glucose regulatory system of the healthy body to understand diabetes. Blood glucose concentration returns to a constant level after eating and is maintained during …

The Comparison Of Hamstring/Quadriceps Strength Ratio In The Dominant Versus The Non-Dominant Leg Of Elite Female Artistic Gymnasts, Marina Moure

Human Movement Studies & Special Education Theses & Dissertations

The majority of the injuries in women's artistic gymnastics occur in the lower limbs (Marshall et al, 2007). Hamstring muscle strains are prevalent in sports that involve sprinting (Ekstrand & Quillist, 1985; Orchard, 2001; Croisier et al., 2008) with a high reinjury ratio (Orchard, 1993; Orchard, 1997). Recent studies have linked an increase of muscle injury rate in the lower limbs to strength muscle imbalance between legs and the relation between the hamstring and quadriceps strength (Croisier et al., 2002; Yamamoto, 2008; Sugiura et al, 2008). In order to determine if there is an imbalance in women's artistic gymnastics, forty-three …

Magnification Loupes In U.S. Entry-Level Dental Hygiene Programs, Leslie Mchaney Congdon

Dental Hygiene Theses & Dissertations

Purpose: The purpose of this study was to determine policies and practices regarding magnification loupes among accredited dental hygiene programs as measured by a 31- item, self-designed questionnaire titled Magnifying Loupes in U.S. Entry Level Dental Hygiene Programs. In addition, the study compared policies among dental hygiene programs in two year versus four year programs in terms of requirements for the use of magnification loupes.

Methods: After institutional review board approval, the questionnaire was emailed via Survey Monkey to 303 entry-level dental hygiene programs. An overall response rate of 75% was obtained. Data were analyzed using descriptive statistics and …

Domestic Violence As A Contributing Factor To Juvenile Substance Use, Victoria Felicitas Sophie Danz

Sociology & Criminal Justice Theses & Dissertations

This study examines the relationship between witnessing violence in the home and juvenile substance use. Data was used from an existing study and variables were recoded to be of best use for this particular work. This study found that witnessing acts of violence can lead a juvenile into drug use, but other factors are more likely to have influenced this behavior. The study shows that family and peer use of drugs is a major predictor for juvenile substance use and has a bigger influence on the juvenile's life than witnessing violence. No significant impact on drug use was found between …

Uptake Of Nanoparticles Of Cerium Oxide And Yttrium Oxide By Acanthamoeba Castellanii (Protozoa) And Daphnia Magna (Crustacea), James R. Palmieri, Geneva Gehring, Catherine Minichino, Shaadi F. Elswaifi

Virginia Journal of Science

Currently, nanoparticles are synthesized and used at an unprecedented rate for industrial, medical, and research applications. The use of cerium oxide nanoparticles (CeONP) and yttrium oxide nanoparticles (YtONP) results in their spread as contaminants into the environment. Once in the environment, CeONP and YtONP can be taken up by organisms in the food chain where they may pose a public health risk. In this study we determine whether Acanthamoeba castellanii and Daphnia magna uptake CeONP or YtONP from their environment and thereby play a role in the transmission of the nanoparticles. Using electron microscopy, orgranisms exposed to the nanoparticles were …

Effect Of Body Mass And Added Mass On Treadmill Performance, Rachel Elizabeth Walker

Human Movement Studies & Special Education Theses & Dissertations

Strenuous physical activity in extreme environments is an important part of the activities of military personnel. The average infantry combat load for an infantry on the loaded tasks. Subjects performed an outdoor 4.8-km run and four maximal treadmill tests wearing the loads listed above. Subjects' pulmonary function was tested with load prior to each treadmill session. Peak values of heart rate, VO₂, exercise ventilation, and respiratory exchange ratio were measured at the end of each maximal treadmill test. Significant decreases were found in pulmonary function measures (FEV₁, FVC and MVV) with increasing load. Most peak responses …

Evaluation Of A Novel Non-Penetrating Electrode For Use In Dna Vaccination, Amy Donate, Domenico Coppola, Yolmari Cruz, Richard Heller

Bioelectrics Publications

Current progress in the development of vaccines has decreased the incidence of fatal and non-fatal infections and increased longevity. However, new technologies need to be developed to combat an emerging generation of infectious diseases. DNA vaccination has been demonstrated to have great potential for use with a wide variety of diseases. Alone, this technology does not generate a significant immune response for vaccination, but combined with delivery by electroporation (EP), can enhance plasmid expression and immunity. Most EP systems, while effective, can be invasive and painful making them less desirable for use in vaccination. Our lab recently developed a non-invasive …

Evidence-Based Practice In Clinical Athletic Training Education, Dorice A. Hankemeier

Human Movement Studies & Special Education Theses & Dissertations

Evidence-Based Practice (EBP) concepts are becoming more prevalent in the educational curricula of nursing, medicine, physical therapy, and athletic training. The infusion of EBP in the clinical education experience of students has been slow especially in athletic training. The aim of Project I was to investigate approved clinical instructors (ACIs) experience and implementation of EBP with students through emergent design qualitative interviews. Project II was designed to develop and establish the reliability of the Evidence-Based Concepts Assessment (EBCA) to assess athletic trainers' perceived importance, attitudes & beliefs, knowledge, confidence, accessibility, and barriers of EBP. Project III investigated the importance, knowledge, …

Adoption Of Electronic Health Records By Admitting Physicians: A Heuristic Model, John Sharon Hudson

Health Services Research Dissertations

Background: Although hospital electronic health records (EHRs) are generally perceived to improve care, physician resistance may hinder EHR adoption.

Purpose: This study uses constructs from diffusion of innovations and resource dependence theories to predict adoption and rate of adoption of an EHR by admitting physicians from three of ten hospitals in a highly integrated health system in Virginia. Functions evaluated: computerized physician order entry (CPOE), electronic history and physical (EH&P) and electronic discharge summary (EDS). The study tested hypotheses that adoption would be associated with: working at larger, academic hospitals; financial alignment; larger physician groups; office EHR; youth; males; medical …