Medicine and Health Sciences Commons^™

Home Health Care Effect In Post-Discharge Return To Hospital, Danielle M. Siclovan

Dissertations (1934 -)

Background: Home Health Care (HHC), the most commonly used bridge strategy for transitioning from hospital to home-based care, is expected to contribute to ongoing readmission avoidance efforts. However, evidence suggests HHC patients are readmitted more frequently than patients without HHC. Determining the effectiveness of HHC as a readmission reduction strategy requires a comparison sample of patients with similar characteristics referred and not referred to HHC. Methods: For this matched-sample comparative study, the available sample (n=18,774) included 3,629 patients referred to HHC and 15,145 non-HHC patients, from which 2,718 pairs matched 1:1 were obtained using exact and Mahalanobis distance matching. Unadjusted …

Qualitative Exploration Of The Perceptions Of Nursing Undergraduates Regarding Family Care At End-Of-Life, Penny A. Alt-Gehrman

Dissertations (1934 -)

Background/Purpose: Family care at end-of-life is delivered by nurses and includes communication and explanations, providing emotional support for the family, creating an environment in which death occurs with dignity, providing privacy, facilitating visitation, and honoring and meeting cultural and personal family values (Beckstrand et al., 2011; Bloomer et al., 2013; Cronin et al., 2015; Heidari & Norouzadeh, 2014). There appears to be a gap in the empirical evidence and literature on this topic. Regarding the knowledge and comfort of student nurses, and subsequently nurses, in family care at the end-of-life, there is disparity. To determine what must be taught to …

Understanding Water Diffusion In Experimental Spinal Cord Injury Remote From Injury Epicenter, Alice Motovylyak

Dissertations (1934 -)

Diffusion tensor imaging (DTI) has demonstrated success as a biomarker of spinal cord injury (SCI) severity as shown from numerous preclinical studies. However, artifacts from stabilization hardware at the lesion have precluded its use for longitudinal assessments. Previous research has documented ex vivo diffusion changes in the spinal cord both caudal and rostral to the injury epicenter. The aim of this dissertation was to quantify the structural changes that lead to different diffusion measures in the rat cervical spinal cord after a thoracic contusion injury in an attempt to find a biomarker of injury. Animals received a thoracic contusion injury …

An Emancipatory Approach To Cultural Competency: The Application Of Critical Race, Postcolonial, And Intersectionality Theories, Linda M. Wesp, Victoria Scheer, Ashley Ruiz, Kimberly Walker, Jennifer Weitzel, Leslie Shaw, Peninnah M. Kako, Lucy Mkandawire-Valhmu

College of Nursing Faculty Research and Publications

Nurses teach, work, and conduct research in an increasingly hostile sociopolitical climate where health inequities persist among marginalized communities. Current approaches to cultural competency do not adequately equip nurses to address these complex factors and risk perpetuating stereotypes and discrimination. A theory-driven emancipatory approach to cultural competency will instead lead to lasting change and uphold the core nursing value of commitment to social justice. This article explicates key tenets of critical race, postcolonial feminist, and intersectionality theories and then applies them, using an emancipatory approach to cultural competency that can reshape nursing education, research, and practice.

Developmental Chromatin Restriction Of Pro‐Growth Gene Networks Acts As An Epigenetic Barrier To Axon Regeneration In Cortical Neurons, Ishwariya Venkatesh, Vatsal Mehra, Zimei Wang, Ben Califf, Murray G. Blackmore

Biomedical Sciences Faculty Research and Publications

Axon regeneration in the central nervous system is prevented in part by a developmental decline in the intrinsic regenerative ability of maturing neurons. This loss of axon growth ability likely reflects widespread changes in gene expression, but the mechanisms that drive this shift remain unclear. Chromatin accessibility has emerged as a key regulatory mechanism in other cellular contexts, raising the possibility that chromatin structure may contribute to the age‐dependent loss of regenerative potential. Here we establish an integrated bioinformatic pipeline that combines analysis of developmentally dynamic gene networks with transcription factor regulation and genome‐wide maps of chromatin accessibility. When applied …

Using Enamel Matrix Derivative To Improve Treatment Efficacy In Periodontal Furcation Defects, Reza Masaeli, Kavosh Zandsalimi, Zahra Lotfi, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Purpose

Furcations are complicated periodontal defects. Untreated furcations lead to loss of the involved teeth and supporting tissues. It has been demonstrated that regenerative biomaterials are beneficial in reconstruction of the bone surrounding furcation‐affected teeth. These biomaterials range from bone grafts and nonresorbable/resorbable barrier membranes to biologics that are able to trigger inactive regenerative processes in periodontal tissues. Selection of appropriate material(s) to treat furcations is challenging. The aim of this article is to provide a comparative outlook on different biomaterials applicable in regeneration of furcations with a focus on enamel matrix derivative (EMD).

Methods

Scientific databases including PubMed/MEDLINE, ScienceDirect, …

Home-Based, Square-Stepping Exercise Program Among Older Adults With Multiple Sclerosis: Results Of A Feasibility Randomized Controlled Study, Emerson Sebastião, Edward Mcauley, Ryosuke Shigematsu, Brynn C. Adamson, Rachel E. Bollaert, Robert W. Motl

Exercise Science Faculty Research and Publications

There is very little known about exercise rehabilitation approaches for older adults with multiple sclerosis (MS), yet this growing segment of the MS population experiences declines in cognition and mobility associated with disease progression and aging. We conducted a RCT examining the feasibility of a 12-week, home-based Square-Stepping Exercise (SSE) program in older adults with MS. Older adults with MS (N = 26) with mild-to-moderate levels of disability were recruited and randomized into the intervention (i.e., SSE) or a minimal activity, attention-control conditions. Participants in the SSE condition received a mat for home-based practice of the step patterns, an …

Locomotor Adaptations To Prolonged Step-By-Step Frontal Plane Trunk Perturbations In Young Adults, Eric R. Walker, Allison S. Hyngstrom, Tanya Onushko, Brian D. Schmit

Physical Therapy Faculty Research and Publications

The purpose of this study was to quantify the magnitude and time course of dynamic balance control adaptations to prolonged step-by-step frontal plane forces applied to the trunk during walking. Healthy young participants (n = 10, 5 female) walked on an instrumented split-belt treadmill while an external cable-driven device applied frontal plane forces to the trunk. Two types of forces were applied: 1) forces which accentuated COM movement in the frontal plane (destabilizing) and 2) forces which resisted COM movement in the frontal plane (stabilizing). We quantified dynamic balance control using frontal plane measures of (1) the extent of center …

Lean Mass Mediates The Relation Between Temporal Summation Of Pain And Sex In Young Healthy Adults, Abdulaziz Awali, Ali Alsouhibani, Marie K. Hoeger Bement

Physical Therapy Faculty Research and Publications

Background

Previous studies have shown that women experience greater temporal summation (TS) of pain than men using a repetitive thermal stimulus. These studies, however, did not individualize the thermal stimulus to each subject’s thermal pain sensitivity. The aim of this study was to investigate sex differences in TS using an individualized protocol and potential mediators that have been shown to influence TS including physical activity and body composition.

Methods

Fifty young healthy men and women (21 men) participated in the study. Subjects completed TS testing on the right forearm using a repetitive thermal stimulus at a temperature that the subject …

Exercise-Induced Pain And Analgesia? Underlying Mechanisms And Clinical Translation, Kathleen A. Sluka, Laura Frey-Law, Marie K. Hoeger Bement

Physical Therapy Faculty Research and Publications

No abstract provided.

Aligning Evidence-Based Practice With Translational Research: Opportunities For Clinical Practice Research, Marianne E. Weiss, Kathleen L. Bobay, Meg Johantgen, Maria Shirey

College of Nursing Faculty Research and Publications

Magnet(R) and other organizations investing resources in evidence-based practice (EBP) are ideal laboratories for translational nursing research. Translational research, the study of implementation of evidence into practice, provides a unique opportunity to leverage local EBP work for maximum impact. Aligning EBP projects with rigorous translational research can efficiently meet both EBP and research requirements for Magnet designation or redesignation, inform clinical practice, and place organizations at the leading edge of practice-based knowledge development for the nursing discipline.

The Power Of Play: A Pediatric Role In Enhancing Development In Young Children, Michael Yogman, Andrew Garner, Jeffrey Hutchinson, Kathy Hirsh-Pasek, Roberta Michnick Golinkoff, Virginia Keane, Rebecca Baum, Thresia Gambon, Arthur Lavin, Gerri Mattson, Lawrence Wissow, Sahron Berry, Amy Starin, Edward Christopherson, Abigail Schlesinger, Karen S. Smith, David L. Hill, Nusheen Ameenuddin, Yolanda Reid Ghassiakos, Corinn Cross, Rhea Boyd, Robert Mendelson, Megan A. Moreno, Wendy Sue Swanson, Justin Smith, Kristopher Kaliebe, Jennifer Pomeranz, Brian Wilcox, Thomas Mcpheron

College of Nursing Faculty Research and Publications

Children need to develop a variety of skill sets to optimize their development and manage toxic stress. Research demonstrates that developmentally appropriate play with parents and peers is a singular opportunity to promote the social-emotional, cognitive, language, and self-regulation skills that build executive function and a prosocial brain. Furthermore, play supports the formation of the safe, stable, and nurturing relationships with all caregivers that children need to thrive.

Gait Variability And Energy Cost Of Overground Walking In Persons With Multiple Sclerosis: A Cross-Sectional Study, Emerson Sebastião, Rachel E. Bollaert, Elizabeth A. Hubbard, Robert W. Motl

Exercise Science Faculty Research and Publications

Objective: This study examined the associations between gait variability based on common spatiotemporal parameters and energetic cost of walking in persons with multiple sclerosis.

Design: Eighty-six persons with multiple sclerosis underwent the 6-min walk while wearing a portable metabolic unit. The cost of walking was generated by dividing the net steady-state VO₂ (milliliter per kilogram per minute) by walking speed during the 6-min walk. Participants further completed two trials of walking on the GAITRite mat at a self-selected pace for measuring spatiotemporal parameters. Variability of step length, step time, stride length, swing time, stance time, stride velocity, and single- …

Management Of Cervical Root Fracture Injury In A Patient With Epilepsy: Case Report With 5-Year Follow-Up, Elif Ataol, Gizem Erbaş Ünverdi, H. Cem Güngör

School of Dentistry Faculty Research and Publications

The difficulty in providing stability to the coronal segment makes cervical root fracture one of the most challenging dental traumatic injury. This type of injury is less frequent in children. However, due to their serious consequences and poor prognosis, tooth loss may occur. This report presents the management of a case of cervical root fracture in an 11-year-old patient with epilepsy. The stabilization of the root-fractured tooth with a splint failed due to the recurrent seizures the patient had. Coronal fragment was removed and vital root submergence was performed in order to support the alveolar growth. The natural tooth crown …

Response To ‘Aspih Standards For Simulation-Based Education: Process Of Consultation, Design And Implementation’, Kristina Dreifuerst, Teresa Gore, Bette Mariani

College of Nursing Faculty Research and Publications

No abstract provided.

Patients’ Perspectives On Engaging In Their Healthcare While Hospitalized, Teresa Jerofke-Owen, Jennifer Jean Dahlman

College of Nursing Faculty Research and Publications

Aims and objectives

To examine patients’ experiences and preferences for engaging in their healthcare while hospitalised.

Background

Promoting patient engagement or involvement in healthcare has become an important component of contemporary, consumer‐oriented approaches to quality care. Previous research on patient engagement highlights that preferences for engagement are not assessed while hospitalised, leading to patient role confusion and frustration.

Methods

Semistructured interviews were conducted with patients from January–March 2017 to examine their experiences and preferences for engaging in their care while hospitalised on medical‐surgical units in the United States. Inductive thematic analysis was used to uncover the themes from the interview …

Moral Distress In Critical Care Nursing: The State Of The Science, Natalie S. Mcandrew, Jane Leske, Kathryn Schroeter

College of Nursing Faculty Research and Publications

Background:

Moral distress is a complex phenomenon frequently experienced by critical care nurses. Ethical conflicts in this practice area are related to technological advancement, high intensity work environments, and end-of-life decisions.

Objectives:

An exploration of contemporary moral distress literature was undertaken to determine measurement, contributing factors, impact, and interventions.

Review Methods:

This state of the science review focused on moral distress research in critical care nursing from 2009 to 2015, and included 12 qualitative, 24 quantitative, and 6 mixed methods studies.

Results:

Synthesis of the scientific literature revealed inconsistencies in measurement, conflicting findings of moral distress and nurse demographics, problems …

Current Medical Research: Summer/Fall 2017, Richard J. Fehring, Mary Lee Barron

College of Nursing Faculty Research and Publications

This issue of Current Medical Research (CMR) includes studies that provide evidence that use of natural family planning (NFP) can be helpful for subfertile couples wishing to achieve a pregnancy, the effectiveness of a method of NFP during breastfeeding, and the effects of using NFP on marital relationships. This review also includes evidence on predicting the sex of a baby by timing intercourse, evidence that brain injuries can be reflected in changes in the menstrual cycle, and that women prefer methods of family planning that have no side effects. The issue ends with an in-depth review of new technologies that …

Associations Of Functional Connectivity And Walking Performance In Multiple Sclerosis, Rachel E. Bollaert, Kyle Poe, Elizabeth A. Hubbard, Robert W. Motl, Lara A. Pilutti, Curtis L. Johnson, Bradley P. Sutton

Exercise Science Faculty Research and Publications

Background

Persons with multiple sclerosis (MS) often demonstrate impaired walking performance, and neuroimaging methods such as resting state functional connectivity. (RSFC) may support a link between central nervous system damage and disruptions in walking.

Objectives

This study examined associations between RSFC in cortical networks and walking performance in persons with MS.

Methods

29 persons with MS underwent 3-T brain magnetic resonance imaging (MRI) and we computed RSFC among 68 Gy matter regions of interest in the brain. Participants completed the Timed 25-foot Walk as a measure of walking performance. We examined associations using partial Pearson product-moment correlation analyses (r …

Phase-Iii, Randomized Controlled Trial Of The Behavioral Intervention For Increasing Physical Activity In Multiple Sclerosis: Project Bipams, Robert W. Motl, Brian M. Sandroff, Brooks C. Wingo, Justin Mccroskey, Lara A. Pilutti, Gary R. Cutter, Rachel E. Bollaert, Edward Mcauley

Exercise Science Faculty Research and Publications

Background

We propose a phase-III, randomized controlled trial (RCT) that examines the effectiveness of a behavioral intervention based on social cognitive theory (SCT) and delivered through the Internet using e-learning approaches for increasing physical activity and secondary outcomes (e.g., symptoms) in a large sample of people with multiple sclerosis (MS) residing throughout the United States.

Methods/design

The proposed phase-III trial will use a parallel group, RCT design that examines the effect of a 6-month behavioral intervention for increasing physical activity and secondarily improving mobility, cognition, symptoms, and quality of life (QOL) in persons with MS. The primary outcome is accelerometer-measured …

In Vitro Effect Of Graphene Structures As An Osteoinductive Factor In Bone Tissue Engineering: A Systematic Review, Dorsa Mohammadrezaei, Hossein Golzar, Maryam Rezai Rad, Meisam Omidi, Hamid Rashedi, Fatemeh Yazdian, Arash Khojasteh, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Graphene and its derivatives have been well‐known as influential factors in differentiating stem/progenitor cells toward the osteoblastic lineage. However, there have been many controversies in the literature regarding the parameters effect on bone regeneration, including graphene concentration, size, type, dimension, hydrophilicity, functionalization, and composition. This study attempts to produce a comprehensive review regarding the given parameters and their effects on stimulating cell behaviors such as proliferation, viability, attachment and osteogenic differentiation. In this study, a systematic search of MEDLINE database was conducted for in vitro studies on the use of graphene and its derivatives for bone tissue engineering from January …

In Reply, Yeshwant B. Rawal, Joshua S. Brandner, Louis J. Kim, Jasjit K. Dillon

School of Dentistry Faculty Research and Publications

No abstract provided.

Change In Bone Mineral Density Among High Frequency Apheresis Blood Donors, Walter Bialkowski

Dissertations (1934 -)

Exposure to citrate anticoagulant during apheresis blood donation induces significant decreases in serum ionized calcium with subsequent perturbations to parathyroid hormone, vitamin D, and markers of bone remodeling. Cross-sectional studies of bone mineral density (BMD) among apheresis donors exhibit conflicting results. Resolving the potential impact of the highest apheresis donation frequency represents a significant knowledge gap in ensuring adequate protections for volunteer apheresis blood donors. ALTRUYST (NCT02655055) was a randomized, longitudinal, controlled clinical trial designed to determine if repeated exposure to citrate through apheresis donation reduces BMD. Male donors, 18-65 years of age with no more than five previous apheresis …

Response To ‘Aspih Standards For Simulation-Based Education: Process Of Consultation, Design And Implementation’, Kristina Dreifuerst, Teresa Gore, Bette Mariani

College of Nursing Faculty Research and Publications

No abstract provided.

People Or Profit: A Comparison Of Health Care In Brazil And The United States, Alexandre A. Martins

Theology Faculty Research and Publications

This essay offers a reflection about the increasing influence of profit in Catholic health care. Based on Jesus' teaching that shows that the need of the wounded person on the street comes first (Luke 10: 25-37), Catholic health care ministry has the challenge to create services where people, not profit, come first.

Motor Compensation During Lower Limb Pedaling After Stroke, Brice Thomas Cleland

Dissertations (1934 -)

Long-term motor dysfunction in the lower limb is common after stroke. One potential contributor is motor compensation, a behavior in which functions originally performed by the paretic limb are performed by the non-paretic limb. Compensation in chronic stroke may contribute to long-term motor dysfunction by limiting functional ability, impairing future recovery, and eliciting maladaptive neuroplasticity. The purpose of this dissertation was to describe the impact of compensation on motor function and brain activation during lower limb pedaling and identify elements that produce this behavior. To achieve this purpose, we evaluated muscle activation and motor performance when compensation was prevented. During …

A Biomechanical Simulation Of Musculoskeletal Kinematics During Ambulation, Alex Thomas

Master's Theses (2009 -)

The purpose of this study was to validate a 3D musculoskeletal model in OpenSim and assess OpenSim’s ability to determine muscle-length variation during ambulation. An 18 camera motion capture system was used to analyze 20 healthy individuals between the ages of 18 and 35. Following data collection, the data was processed through OpenSim and Visual3D. The kinematic output processed through the OpenSim model was then compared to the kinematic output of the validated Visual3D model to validate the OpenSim model. Muscle fiber length data obtained from the same experimental data was compared to control data to assess OpenSim’s muscle analysis …

Orthodontic Treatment Planning Using Direct Visual Approximation Of Arch Length Discrepancy And Cephalometric Analyses, Kathleen Rouse Vaught

Master's Theses (2009 -)

Introduction: Space analysis and radiographic analyses are crucial elements in developing an orthodontic treatment plan. It is imperative that the orthodontist makes accurate measurements in order to come up with the most effective treatment options for each patient. Some practitioners refrain from direct measurements to determine arch length discrepancies and instead determine the amount of crowding by using direct visual approximation. In addition, more orthodontists do not routinely trace all cephalograms taken. If more and more orthodontists are using direct visual approximation to determine angular cephalometric measurements, it is important to assess the accuracy and reliability of these measurements. This …

Comparison Of Immediate Vs. Delayed Recall Of Orthodontic Information Following An Electronic Reminder, Michael Lenz

Master's Theses (2009 -)

Patients and parents in dentistry often do not remember important information disclosed during the informed consent process, so improvement in the delivery of information is needed. This study explored the effect of an emailed narrated instructional PowerPoint on the immediate vs. delayed recall and comprehension of informed consent information in orthodontics. Thirty-two subjects were recruited from a university and private practice orthodontic clinic. At the initial visit, subjects were alternately assigned to one of two groups and were presented with a mock orthodontic treatment plan and informed consent presentation for a pretend patient. Immediately following the presentation, the subjects’ verbal …

Orthodontic Open-Coil Spring Deactivation Forces Differ With Varying Activation Levels, Ryan Lubinsky

Master's Theses (2009 -)

Coil springs are used in orthodontics to deliver forces to move teeth. However, the optimal amount of activation to produce predictable, continuous deactivation forces, for the purpose of orthodontic tooth movement, is unclear. The purpose of this study was to evaluate the deactivation force characteristics of nickel-titanium open-coil springs after varying levels of activation. Methods: Four open-coil spring products were evaluated: Dentsply GAC 100 gram and 150 gram, Orthoclassic Orthodontics Medium 150 gram, and American Orthodontics nickel-titanium springs. Open-coil springs were compressed (activation) with a universal testing machine to 20, 40, 60, or 80% of original length (15 mm; n=15/product/activation …