Medicine and Health Sciences Commons^™

Effect Of Airborne-Particle Abrasion On 3-Dimensional Surface Roughness And Characteristic Failure Load Of Fiber-Reinforced Posts, Georgios Maroulakos, Michael W. Wanserski, Michelle M. Wanserski, Ethan J. Schuler, Colin P. Egan, Geoffrey A. Thompson

School of Dentistry Faculty Research and Publications

Statement of problem

Debonding is the most common complication of fiber-reinforced posts (FRPs). Airborne-particle abrasion (APA) has been suggested to increase resin cement adhesion to the surface of FRPs. However, which abrasion protocol is the most favorable is unclear.

Purpose

The purpose of this in vitro study was to compare the surface roughness and characteristic failure load of three FRP systems following different APA protocols.

Material and methods

A total of 150 posts from 3 manufacturers (glass FRP, quartz FRP, and zirconia-enriched glass FRP) were randomly assigned to different surface treatments (NT: no treatment—control; E0: cleaned with 96% ethanol solution; …

Preferences For Physical Activity: A Conjoint Analysis Involving People With Chronic Knee Pain, Daniel Pinto, Ulf Bockenholt, Jungwha Lee, Rowland W. Chang, Leena Sharma, Daniel J. Finn, Allen W. Heinemann, Jane Louise Holl, Paul D. Hansen

Physical Therapy Faculty Research and Publications

Objective

To investigate individual preferences for physical activity (PA) attributes in adults with chronic knee pain, to identify clusters of individuals with similar preferences, and to identify whether individuals in these clusters differ by their demographic and health characteristics.

Design

An adaptive conjoint analysis (ACA) was conducted using the Potentially All Pairwise RanKings of all possible Alternatives (PAPRIKA) method to determine preference weights representing the relative importance of six PA attributes. Cluster analysis was performed to identify clusters of participants with similar weights. Chi-square and ANOVA were used to assess differences in individual characteristics by cluster. Multinomial logistic regression was …

Roles For The Uptake2 Transporter Oct3 In Regulation Of Dopaminergic Neurotransmission And Behavior, Paul J. Gasser

Biomedical Sciences Faculty Research and Publications

Transporter-mediated uptake determines the peak concentration, duration, and physical spread of released monoamines. Most studies of monoamine clearance focus on the presynaptic uptake₁ transporters SERT, NET and DAT. However, recent studies have demonstrated the expression of the uptake₂ transporter OCT3 (organic cation transporter 3), throughout the rodent brain. In contrast to NET, DAT and SERT, OCT3 has higher capacity and lower affinity for substrates, is sodium-independent, and is multi-specific, with the capacity to transport norepinephrine, dopamine, serotonin and histamine. OCT3is insensitive to inhibition by cocaine and antidepressant drugs but is inhibited directly by the glucocorticoid hormone corticosterone. Thus, …

Mathematical Modeling Of Oxygen Transfer In Porous Scaffolds For Stem Cell Growth: The Effects Of Porosity, Cell Type, Scaffold Architecture And Cell Distribution, Saeid Atashrouz, Ali Hatampoor, Amir Yadegari, Hamed Ghasemi, Lobat Tayebi, Morteza Rasoulianboroujeni

School of Dentistry Faculty Research and Publications

Oxygen plays a key role in human mesenchymal stem cell growth. Without adequate oxygen (hypoxic condition), cells are not able to survive, proliferate, and migrate. The objective of the present study is to investigate oxygen transfer through the cell-seeded scaffolds stored in static or dynamic bioreactors using a mathematical model. The effects of porosity, cell type, scaffold architecture and cell distribution as potential effective parameters on oxygen transfer kinetics were examined. The results suggest the substantial effect of porosity and cell type on the oxygen concentration within the scaffold compared to scaffold architecture (homogeneous vs. gradient). The obtained data …

Ballroom Dance For Persons With Multiple Sclerosis: A Pilot Feasibility Study, Alexander V. Ng, Sheri Bunyan, Jimin Suh, Pamela Huenink, Tyler Gregory, Shannon Gambon, Deborah Miller

Exercise Science Faculty Research and Publications

Purpose: The purpose of this study was to evaluate the exercise intensity and feasibility of recreational ballroom dance for persons with multiple sclerosis (MS).

Methods: Seven persons with MS participated in 2 one-hour dance sessions per week for 6 weeks. Dance types included rumba, foxtrot, waltz, and push-pull. Six other persons with MS comprised a control group that did not dance. Heart rate and ratings of perceived exertion (RPE) were monitored during the sessions. Outcomes included: quality of life, fatigue, depression, self-efficacy, timed up and go, Berg Balance Scale, Dynamic Gait Index and the Multiple Sclerosis Functional Composite comprising 9-hole …

Mental Imagery Practice As A Therapy For Naming Impairments: A Preliminary Study, Subhash Bhatnagar, Bridget Patek, Yasmeen Khan-Ansari, Naveen K. Bansal, Hugh Buckingham, Lotfi Hacein-Bey

Speech Pathology and Audiology Faculty Research and Publications

Background

Anomia remains one of the most recalcitrant linguistic disruptions in aphasia to treat. Developing successful interventions to address the word-finding deficits are complicated by the post-stroke symptom variability and inconsistent recovery patterns associated with anomia. Most of the current treatment methods, with a focus on specific compensating techniques and the repetitive practice of a limited set of items, have had variable success in naming treatment. However, it has not been possible to predict the gains in generalizing the learning beyond the stimuli used in practice or the controlled clinical setting. In this preliminary case study, we explore the value …

A Principal Components Analysis Approach To Quantifying Foot Clearance And Foot Clearance Variability, Lauren C. Benson, Stephen C. Cobb, Allison S. Hyngstrom, Kevin G. Keenan, Jake Luo, Kristian M. O'Connor

Physical Therapy Faculty Research and Publications

Low foot clearance and high variability may be related to falls risk. Foot clearance is often defined as the local minimum in toe height during swing; however, not all strides have this local minimum. The primary purpose of this study was to identify a nondiscrete measure of foot clearance during all strides, and compare discrete and nondiscrete measures in ability to rank individuals on foot clearance and variability. Thirty-five participants (young adults [n = 10], older fallers [n = 10], older nonfallers [n = 10], and stroke survivors [n = 5]) walked overground while lower extremity 3D kinematics were recorded. …

Brain Activation During Passive And Volitional Pedaling After Stroke, Brice T. Cleland, Sheila M. Schindler-Ivens

Physical Therapy Faculty Research and Publications

Background: Prior work indicates that pedaling-related brain activation is lower in people with stroke than in controls. We asked whether this observation could be explained by between-group differences in volitional motor commands and pedaling performance. Methods: Individuals with and without stroke performed passive and volitional pedaling while brain activation was recorded with functional magnetic resonance imaging. The passive condition eliminated motor commands to pedal and minimized between-group differences in pedaling performance. Volume, intensity, and laterality of brain activation were compared across conditions and groups. Results: There were no significant effects of condition and no Group × Condition …

Clinical Decision-Making For Thrombolysis Of Acute Minor Stroke Using Adaptive Conjoint Analysis, Ava L. Liberman, Daniel Pinto, Sara K. Rostanski, Daniel L. Labovitz, Andrew M. Naidech, Shyam Prabhakaran

Physical Therapy Faculty Research and Publications

Introduction:

There is practice variability in the treatment of patients with minor ischemic stroke with thrombolysis. We sought to determine which clinical factors physicians prioritize in thrombolysis decision-making for minor stroke using adaptive conjoint analysis.

Methods:

We conducted our conjoint analysis using the Potentially All Pairwise RanKings of all possible Alternatives methodology via the 1000Minds platform to design an online preference survey and circulated it to US physicians involved in stroke care. We evaluated 6 clinical attributes: language/speech deficits, motor deficits, other neurological deficits, history suggestive of increased risk of complication from thrombolysis, age, and premorbid disability. Survey participants were …

Recommendations For The Conduct Of Economic Evaluations In Osteoporosis: Outcomes Of An Experts’ Consensus Meeting Organized By The European Society For Clinical And Economic Aspects Of Osteoporosis, Osteoarthritis And Musculoskeletal Diseases (Esceo) And The Us Branch Of The International Osteoporosis Foundation, M. Hiligsmann, J.-Y. Reginster, A.N.A. Tosteson, S.V. Bukata, K.G. Saag, D.T. Gold, P. Halbout, F. Jiwa, E.M. Lewiecki, Daniel Pinto, J.D. Adachi, N. Al-Daghri, O. Bruyère, M. Chandran, C. Cooper, N.C. Harvey, T.A. Einhorn, J.A. Kanis, D.L. Kendler, O.D. Messina, R. Rizzoli, L. Si, S. Silverman

Physical Therapy Faculty Research and Publications

Summary

Economic evaluations are increasingly used to assess the value of health interventions, but variable quality and heterogeneity limit the use of these evaluations by decision-makers. These recommendations provide guidance for the design, conduct, and reporting of economic evaluations in osteoporosis to improve their transparency, comparability, and methodologic standards.

Introduction

This paper aims to provide recommendations for the conduct of economic evaluations in osteoporosis in order to improve their transparency, comparability, and methodologic standards.

Methods

A working group was convened by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis to make recommendations for the design, conduct, …

Patients’ Preferences For Osteoarthritis Treatment: The Value Of Stated-Preference Studies, Mickael Hiligsmann, Daniel Pinto, Elaine Dennison, Nasser Al-Daghri, Charlotte Beaudart, Jaime Branco, Olivier Bruyère, Philip G. Conaghan, Cyrus Cooper, Gabriel Herrero-Beaumont, Famida Jiwa, Willem Lems, Thierry Thomas, Nicola Veronese, Jean-Yves Reginster

Physical Therapy Faculty Research and Publications

No abstract provided.

Mice, Acorns, And Lyme Disease: A Case Study To Teach The Ecology Of Emerging Infectious Diseases, Laurieann Klockow

Biomedical Sciences Faculty Research and Publications

Ebola, Zika, the recall of contaminated lettuce - these are just a few recent outbreaks making headlines. Students should be able to connect what they learn in their biology courses to explain these events happening around them. Unfortunately, students do not necessarily make those connections. Therefore, it is important, as instructors, to provide opportunities where students engage with societal issues and problems related to course content and case studies, using headlines from the news are one way to do this.

Here I describe a case study about Lyme disease that engages students in learning about the ecology of infectious disease. …

Determinants Of Occupational Injuries Among Building Construction Workers In Kampala City, Uganda, Arthur Kiconco, Nathan Ruhinda, Abdullah Ali Halage, Stephen Watya, William Bazeyo, John C. Ssempebwa, Joseph Byonanebye

Biomedical Sciences Faculty Research and Publications

Background

Globally, about 1000 people die and close to 860,000 people sustain injury at work daily. Injury prevention and control require contextual evidence, although most studies in Uganda have focused on general causes. Factors associated with occupational injuries among building construction workers were assessed in this study.

Methods

A cross-sectional study among building construction workers was conducted in Kampala, Uganda. A standardized semi-structured questionnaire was used to collect data. Three hundred nineteen (319) participants were randomly and proportionately selected from 57 construction sites. Descriptive statistics were used to describe the variables while generalized linear modeling was used to estimate the …

Prefrontal-Accumbens Opioid Plasticity: Implications For Relapse And Dependence, Matthew C. Hearing

Biomedical Sciences Faculty Research and Publications

In addiction, an individual’s ability to inhibit drug seeking and drug taking is thought to reflect a pathological strengthening of drug-seeking behaviors or impairments in the capacity to control maladaptive behavior. These processes are not mutually exclusive and reflect drug-induced modifications within prefrontal cortical and nucleus accumbens circuits, however unlike psychostimulants such as cocaine, far less is known about the temporal, anatomical, and cellular dynamics of these changes. We discuss what is known regarding opioid-induced adaptations in intrinsic membrane physiology and pre-/postsynaptic neurotransmission in principle pyramidal and medium spiny neurons in the medial prefrontal cortex and nucleus accumbens from electrophysiological …

Pediatric Feeding Disorder: Consensus Definition And Conceptual Framework, Praveen S. Goday, Susanna Y. Huh, Alan Silverman, Colleen T. Lukens, Pamela Dodrill, Sherri S. Cohen, Amy Delaney, Mary B. Feuling, Richard J. Noel, Erika Gisel, Amy Kenzer, Daniel B. Kessler, Olaf Kraus De Camargo, Joe Browne, James A. Phalen

Speech Pathology and Audiology Faculty Research and Publications

Pediatric feeding disorders (PFDs) lack a universally accepted definition. Feeding disorders require comprehensive assessment and treatment of 4 closely related, complementary domains (medical, psychosocial, and feeding skill-based systems and associated nutritional complications). Previous diagnostic paradigms have, however, typically defined feeding disorders using the lens of a single professional discipline and fail to characterize associated functional limitations that are critical to plan appropriate interventions and improve quality of life. Using the framework of the World Health Organization International Classification of Functioning, Disability, and Health, a unifying diagnostic term is proposed: “Pediatric Feeding Disorder” (PFD), defined as impaired oral intake that is …

Chronic Stress And Ovarian Function In Female Childhood Cancer Survivors, Theresa Marie Hardy, Mauricio Garnier-Villarreal, Jennifer M. Ohlendorf, Donna O. Mccarthy

College of Nursing Faculty Research and Publications

Objectives: To explore the relationships among perceived stress, biomarkers of hypothalamic–pituitary–adrenal (HPA) activity, gonadotropin levels, and anti-Müllerian hormone (AMH) in female childhood cancer survivors (CCSs).

Sample & Setting: 24 female CCSs from the Royal Hospital for Sick Children in Edinburgh, Scotland, were included in the study.

Methods & Variables: Perceived stress was measured using the Perceived Stress Scale. HPA activity was measured using salivary cortisol and hair cortisol. Ovarian function was measured using serum gonadotropin levels and serum AMH levels. Latent growth curve modeling was used to determine diurnal cortisol slope and intercept. Bayesian structural equation modeling was used to …

On Burr Iii Marshal Olkin Family: Development, Properties, Characterizations And Applications, Fiaz Ahmad Bhatti, Gholamhossein G. Hamedani, Mustafa Ç. Korkmaz, Gauss M. Cordeiro, Haitham M. Yousof, Munir Ahmad

College of Nursing Faculty Research and Publications

In this paper, a flexible family of distributions with unimodel, bimodal, increasing, increasing and decreasing, inverted bathtub and modified bathtub hazard rate called Burr III-Marshal Olkin-G (BIIIMO-G) family is developed on the basis of the T-X family technique. The density function of the BIIIMO-G family is arc, exponential, left- skewed, right-skewed and symmetrical shaped. Descriptive measures such as quantiles, moments, incomplete moments, inequality measures and reliability measures are theoretically established. The BIIIMO-G family is characterized via different techniques. Parameters of the BIIIMO-G family are estimated using maximum likelihood method. A simulation study is performed to illustrate the performance of the …

A Historical Review Of The Catholic Scientists Who Answered The Call Of Humanae Vitae, Richard J. Fehring

College of Nursing Faculty Research and Publications

No abstract provided.

Signs Of Growth And Healing: Health Care And Science, Richard J. Fehring

College of Nursing Faculty Research and Publications

MY ESSAY ON THE HISTORY OF Catholic Natural Family Planning (NFP) scientists (chapter 8 in this volume) ended with discussing scientists who were active during the papacy of John Paul II (1979-2005). This present essay continues with the time period from approximately 2000 to 2018 and, indeed, into the future. My purpose here, however, is to delineate signs of growth and healing in health care and science related to NFP and not to focus on individual NFP scientists. Given that purpose, recent trends in NFP science and historical factors that influence NFP science can provide us with signs of growth …

Safety In Children With Medical Complexity: Our Canaries In The Coal Mine?, Christine A. Schindler, Elisabeth S. Pordes, Steven D. Finkenbinder, K. Jane Lee

College of Nursing Faculty Research and Publications

Purpose of review

The goal of this paper is to describe the complicated and diverse safety risks facing children with medical complexity.

Recent findings

Children with medical complexity have an increased risk of experiencing adverse health outcomes related to multiple comorbidities, the complicated nature of their care, and frequent interactions with the health care system. The safety risks experienced by children with medical complexity are in large part due to the complex nature of their care rather than the specific risks posed by the complicated nature of their illnesses.

Summary

The complicated nature of care for children with medical complexity …

Predeath Grief, Resourcefulness, And Perceived Stress Among Caregivers Of Partners With Young-Onset Dementia, Karie Ruekert Kobiske, Abir K. Bekhet, Mauricio Garnier-Villarreal, Marilyn Frenn

College of Nursing Faculty Research and Publications

More than 200,000 Americans are currently diagnosed with young-onset dementia (YOD). YOD is dementia diagnosed prior to the age of 65. Most persons of YOD are cared for by their partners. Using the theoretical framework of Resilience Theory, this cross-sectional, correlational study examined the moderating effects of personal and social resourcefulness on the relationship between predeath grief and perceived stress among 104 YOD caregiving partners (life partners/spouses) using an online survey platform. Results indicated a large positive correlation between predeath grief and caregiver perceived stress (r = .65; p < .001). Together predeath grief, personal resourcefulness and social resourcefulness explained 51.5% of the variance in perceived stress. Personal resourcefulness did not moderate the relationship. Social resourcefulness did positively moderate this relationship between predeath grief and perceived stress. These findings allow for a better understanding of the caregiving experience for a partner with YOD and creates opportunities for future research studies.

Pediatric Oncology Nurses’ Perceptions Of Prognosis-Related Communication, Amy Rose Newman, Kristin Haglund, Cheryl C. Rodgers

College of Nursing Faculty Research and Publications

Background

Disclosure of prognosis-related information is an essential aspect of communication with pediatric patients with cancer and their families. The nurse is believed to play an important role in this process, but nurse perceptions and experiences have not been well-described.

Purpose

Provide an exploration of pediatric oncology nurses’ experiences with prognosis-related communication (PRC).

Method

Mixed-methods, multiphase design. This paper highlights the qualitative portion of the study.

Findings

Three themes were identified: Importance of collaboration, impact of PRC, and delivery of prognostic information.

Discussion

Collaboration is a critical element of PRC. Nurses are often not included in the disclosure process, which …

Through The Microbial Looking Glass: Premature Labor, Preeclampsia, And Gestational Diabetes: A Scoping Review, Alexis B. Dunn, Lisa Hanson, Leona Vandevusse, Sharon Leslie

College of Nursing Faculty Research and Publications

The influence of microbial factors on adverse perinatal outcomes has become the focal point of recent investigations, with particular interest in the role of the microbiome and probiotic interventions. The purpose of this scoping review was to identify and critique the most recent evidence about these factors as they relate to pregnancies complicated by preeclampsia (PEC), preterm birth (PTB), and gestational diabetes mellitus (GDM). Four databases (PubMed, EMBASE, Web of Science, and Cochrane) were searched for articles published in English in the last 10 years with the concepts of the microbiome, probiotics, and PEC, PTB, or GDM. Forty-nine articles were …

Effect Of Implementing Discharge Readiness Assessment In Adult Medical-Surgical Units On 30-Day Return To Hospital The Readi Randomized Clinical Trial, Marianne E. Weiss, Olga Yakusheva, Kathleen L. Bobay, Linda L. Costa, Ronda G. Hughes, Susan A. Nuccio, Morris Hamilton, Sarah J. Bahr, Danielle M. Siclovan, James Bang

College of Nursing Faculty Research and Publications

Importance: The downward trend in readmissions has recently slowed. New enhancements to hospital readmission reduction efforts are needed. Structured assessment of patient readiness for discharge has been recommended as an addition to discharge preparation standards of care to assist with tailoring of risk-mitigating actions.

Objective: To determine the effect of unit-based implementation of readiness evaluation and discharge intervention protocols on readmissions and emergency department or observation visits.

Design, Setting, and Participants: The Readiness Evaluation and Discharge Interventions (READI) cluster randomized clinical trial conducted in medical-surgical units of 33 Magnet hospitals between September 15, 2014, and March 31, 2017, included all …

Health Policy Engagement Among Graduate Nursing Students In The United States, Pamela B. De Cordova, Mary Beth Wilson Steck, Amber Vermeesch, Natacha Pierre, Audra Rankin, Jennifer M. Ohlendorf, Sherry Lawrence, Anne Derouin

College of Nursing Faculty Research and Publications

Aim

The aim was to understand how health policy education is currently being delivered in the United States’ graduate nursing programs.

Methods

This exploratory cross‐sectional design used an anonymous online survey to target graduate nursing students attending American Association of College of Nursing (AACN) member institutions.

Results

Over 75% of the sample (n = 140) reported taking a dedicated health policy course and 71.5% ( n = 131) of the sample responded that a health policy course was required and an equal distribution among master’s and doctoral students. There was no significant difference between type of graduate degree sought …

A New Leadership Development Model For Nursing Education, Jane M. Miles, Elaine S. Scott

College of Nursing Faculty Research and Publications

Background

Leadership competency is required throughout nursing. Students have difficulty understanding leadership as integral to education and practice. A consistent framework for nursing leadership education, strong scholarship and an evidence base are limited.

Purpose

To establish an integrated leadership development model for prelicensure nursing students that recognizes leadership as a fundamental skill for nursing practice and promotes development of nursing leadership education scholarship.

Method

Summarizing definitions of nursing leadership, conceptualizing leadership development capacity through reviewing trends, and synthesizing existing leadership theories through directed content analysis.

Discussion

Nine leadership skills form the organizing structure for the Nursing Leadership Development Model. Leadership …

Integrating Research And Quality Improvement Using Teamstepps: A Health Team Communication Project To Improve Hospital Discharge, Joseph Beiler, Kristi Opper, Marianne E. Weiss

College of Nursing Faculty Research and Publications

Purpose/Objectives:

The purpose of this article is to describe an innovative approach to the integration of quality improvement and research processes. A project with the objective of improving health team communication about hospital discharge provides an exemplar case.

Description of the Project/Program:

The TeamSTEPPS 10-step action planning guide provided the structure for planning, developing, and evaluating a redesign of interprofessional health team communication to improve hospital discharge led by 2 clinical nurse specialists. The redesign involved development of processes for team bedside rounding, registered nurse bedside shift reports, and briefing tools to support the rounding processes.

Outcome:

Using the TeamSTEPPS …

The Impact Of Maternal Bmi, Gestational Weight Gain, And Breastfeeding On Early Childhood Weight: Analysis Of A Statewide Wic Dataset, Jennifer M. Ohlendorf, Karen Marie Robinson, Mauricio Garnier-Villarreal

College of Nursing Faculty Research and Publications

Early childhood obesity is a persistent health concern with more frequent and significant impact on low-income families. Maternal weight factors impact offspring weight status, but evidence on whether breastfeeding protects against this impact is mixed. This analysis examined a model to predict early childhood obesity risk, simultaneously accounting for maternal pre-pregnancy body mass index (BMI), gestational weight gain, and breastfeeding. The team analyzed 27,016 unique maternal-child dyadic records collected via the Supplemental Nutrition Program for Wisconsin Women, Infants, and Children (WIC) between 2009 and 2011. Generalized Linear Modeling, specifically logistic regression, was used to predict a child's risk …

Effects Of Positive Thinking On Dementia Caregivers’ Burden And Care-Recipients’ Behavioral Problems, Abir K. Bekhet, Mauricio Garnier-Villarreal

College of Nursing Faculty Research and Publications

Most dementia care is provided at home by family members. This caregiving places an additional burden on the family members, which can negatively impact their physical and psychological well-being. The caregivers’ burden can also contribute to behavioral problems in the care-recipients. The purpose of this study was to examine the mediating/moderating effects of positive thinking (PT) on the relationship between caregivers’ burden (embarrassment/anger, patient’s dependency, and self-criticism) and their care-recipients’ behavioral problems (memory, depression, and disruption) in a sample of 100 dementia caregivers. Results indicated that caregivers’ embarrassment, self-criticism, and perception of patient dependency predicts depression in care-recipients, and these …

Restrictive Ventilatory Patterns In Residents Of Continuing Care Retirement Communities, Christine R. Kovach, Murad H. Taani, Crystal-Rae Waltons, Sheryl Kelber, Irwin Margolis

College of Nursing Faculty Research and Publications

Restrictive ventilatory patterns (RVPs) in older adults may contribute to morbidity and decreased quality of life. The purpose of this study was to begin to understand (a) the number of older adults residing in Continuing Care Retirement Communities with RVPs, (b) factors associated with RVP, and (c) whether RVP is associated with ambulation level. This descriptive study was conducted at three sites. RVP was evident in 34 of the 65 participants (52%), and 33 (97%) of these were either moderate or severely restricted. Dementia, dyspnea, kyphosis, and lower muscle strength were significant predictors of RVP. Eighty percent of the nonambulatory …