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Articles 1261 - 1290 of 3247
Full-Text Articles in Medicine and Health Sciences
Long Days Enhance Recognition Memory And Increase Insulin-Like Growth Factor 2 In The Hippocampus, Adriano Dellapolla, Ian Kloehn, Harshida Pancholi, Ben L. Callif, David Wertz, Kayla Rohr, Matthew M. Hurley, Kimberly Baker, Samer Hattar, Marieke R. Gilmartin, Jennifer A. Evans
Long Days Enhance Recognition Memory And Increase Insulin-Like Growth Factor 2 In The Hippocampus, Adriano Dellapolla, Ian Kloehn, Harshida Pancholi, Ben L. Callif, David Wertz, Kayla Rohr, Matthew M. Hurley, Kimberly Baker, Samer Hattar, Marieke R. Gilmartin, Jennifer A. Evans
Biomedical Sciences Faculty Research and Publications
Light improves cognitive function in humans; however, the neurobiological mechanisms underlying positive effects of light remain unclear. One obstacle is that most rodent models have employed lighting conditions that cause cognitive deficits rather than improvements. Here we have developed a mouse model where light improves cognitive function, which provides insight into mechanisms underlying positive effects of light. To increase light exposure without eliminating daily rhythms, we exposed mice to either a standard photoperiod or a long day photoperiod. Long days enhanced long-term recognition memory, and this effect was abolished by loss of the photopigment melanopsin. Further, long days markedly altered …
Development Of 3d Pcl Microsphere/Tio2 Nanotube Composite Scaffolds For Bone Tissue Engineering, Kimia Khoshroo, Tahereh S. Jafarzadeh Kashi, Fathollah Moztarzadeh, Mohammadreza Tahriri, Hossein E. Jazayeri, Lobat Tayebi
Development Of 3d Pcl Microsphere/Tio2 Nanotube Composite Scaffolds For Bone Tissue Engineering, Kimia Khoshroo, Tahereh S. Jafarzadeh Kashi, Fathollah Moztarzadeh, Mohammadreza Tahriri, Hossein E. Jazayeri, Lobat Tayebi
School of Dentistry Faculty Research and Publications
In this research, the three dimensional porous scaffolds made of a polycaprolactone (PCL) microsphere/TiO2 nanotube (TNT) composite was fabricated and evaluated for potential bone substitute applications. We used a microsphere sintering method to produce three dimensional PCL microsphere/TNT composite scaffolds. The mechanical properties of composite scaffolds were regulated by varying parameters, such as sintering time, microsphere diameter range size and PCL/TNT ratio. The obtained results ascertained that the PCL/TNT (0.5 wt%) scaffold sintered at 60 °C for 90 min had the most optimal mechanical properties and an appropriate pore structure for bone tissue engineering applications. The average pore size …
Viscoelastic Properties Of Orthodontic Adhesives Used For Lingual Fixed Retainer Bonding, Demetrios P. Papadogiannis, A. Iliadi, T. Gerard Bradley, N. Silikas, George Eliades, T. Eliades
Viscoelastic Properties Of Orthodontic Adhesives Used For Lingual Fixed Retainer Bonding, Demetrios P. Papadogiannis, A. Iliadi, T. Gerard Bradley, N. Silikas, George Eliades, T. Eliades
School of Dentistry Faculty Research and Publications
Objective
To evaluate the viscoelastic properties of two experimental BPA-free and one BisGMA-based orthodontic resin composite adhesives for bonding fixed retainers.
Methods
A commercially available BisGMA-based (TXA: Transbond LR) and two bisphenol A-free experimental adhesives (EXA and EXB) were included in the study. The viscoelastic behavior of the adhesives was evaluated under static and dynamic conditions at dry and wet states and at various temperatures (21, 37, 50 °C). The parameters determined were shear modulus (G), Young’s modulus (E) under static testing and storage modulus (G1), loss tangent (tan δ) and dynamic viscosity (n*) under …
Cranio-Maxillofacial Reconstruction With Microvascular Radialis Flaps—Parameters And Correlations Of Postoperative Pain Management, Gregor F. Raschke, Winfried Meissner, Andre Peisker, Gabriel Djedovic, Ulrich M. Rieger, Arndt Guentsch, Daria Porwit, Marta Gomez-Dammeier, Stefan Schultze-Mosgau
Cranio-Maxillofacial Reconstruction With Microvascular Radialis Flaps—Parameters And Correlations Of Postoperative Pain Management, Gregor F. Raschke, Winfried Meissner, Andre Peisker, Gabriel Djedovic, Ulrich M. Rieger, Arndt Guentsch, Daria Porwit, Marta Gomez-Dammeier, Stefan Schultze-Mosgau
School of Dentistry Faculty Research and Publications
Objectives
Postoperative pain management is of highest interest for patients undergoing maxillofacial surgery including microvascular reconstructive surgery. Currently, there is a lack of information regarding process and outcome of postoperative pain management after microvascular reconstruction.
Materials and methods
In a prospective clinical study, 31 adults were evaluated on the first postoperative day following microvascular reconstruction with a radial forearm flap using the standardized questionnaire of the Germany-wide project Quality Improvement in Postoperative Pain Management (QUIPS). It enables a standardized assessment of patients’ characteristics, pain parameters, outcome and pain therapy process parameters.
Results
Pain management consisted predominately of premedication with midazolam, …
Evaluation Of A Post-Treatment Follow-Up Program In Patients With Oral Squamous Cell Carcinoma, Andre Peisker, Gregor F. Raschke, Arndt Guentsch, Paul Luepke, Korosh Roshanghias, Stefan Schultze-Mosgau
Evaluation Of A Post-Treatment Follow-Up Program In Patients With Oral Squamous Cell Carcinoma, Andre Peisker, Gregor F. Raschke, Arndt Guentsch, Paul Luepke, Korosh Roshanghias, Stefan Schultze-Mosgau
School of Dentistry Faculty Research and Publications
Objectives
The duration and the frequency of follow-up after treatment of oral squamous cell carcinoma are not standardized in the current literature. The purpose of this study was to evaluate our local standard post-treatment and follow-up protocol.
Materials and methods
Overall, 228 patients treated curatively from 01/2006 to 07/2013 were reviewed. To evaluate the follow-up program, data on the secondary event were used. To determine risk groups, all patients with tumor recurrence were specifically analyzed. Relapse-free rate were estimated by the Kaplan-Meier product limit method. The chi-square test was used to identify independent risk factors for tumor relapse.
Results
In …
Optimizing Anterior Implant Outcome Immediately After Implant Placement And Grafting By Using Patient’S Extracted Teeth: A Case Report, Soni Prasad, Jay Darryl Banez, Despoina Bompolaki, Yvonne Hart
Optimizing Anterior Implant Outcome Immediately After Implant Placement And Grafting By Using Patient’S Extracted Teeth: A Case Report, Soni Prasad, Jay Darryl Banez, Despoina Bompolaki, Yvonne Hart
School of Dentistry Faculty Research and Publications
Optimizing anterior implant outcome using patient’s extracted teeth.
Successful implant treatment in the anterior maxilla is predicated on providing a functional and esthetically acceptable outcome. As well, achieving a predictable ideal emergence profile and soft tissue contour is expected. Placing immediate provisional restorations utilizing the patient’s modified extracted teeth can facilitate initiate facial soft tissue contouring while precluding undue pressure on the surgical site during the early healing phase. This allows for a one stage surgical procedure, fixed provisionalization and ideal tissue contouring.
This clinical report presents the use of a patient’s modified extracted permanent teeth as bonded fixed provisional …
Wellness And Multiple Sclerosis: The National Ms Society Establishes A Wellness Research Working Group And Research Priorities, Robert W. Motl, Ellen M. Mowry, Dawn M. Ehde, Nicholas G. Larocca, Kathy E. Smith, Kathleen Costello, Lynne Shinto, Alexander V. Ng, Amy B. Sullivan, Barbara Geisser, Kevin K. Mccully, Bo Fernhall, Malachy Bishop, Matthew Plow, Patrizia Casaccia, Nancy D. Chiaravalloti
Wellness And Multiple Sclerosis: The National Ms Society Establishes A Wellness Research Working Group And Research Priorities, Robert W. Motl, Ellen M. Mowry, Dawn M. Ehde, Nicholas G. Larocca, Kathy E. Smith, Kathleen Costello, Lynne Shinto, Alexander V. Ng, Amy B. Sullivan, Barbara Geisser, Kevin K. Mccully, Bo Fernhall, Malachy Bishop, Matthew Plow, Patrizia Casaccia, Nancy D. Chiaravalloti
Exercise Science Faculty Research and Publications
Background:
People with multiple sclerosis (MS) have identified “wellness” and associated behaviors as a high priority based on “social media listening” undertaken by the National MS Society (i.e. the Society).
Objective:
The Society recently convened a group that consisted of researchers with experience in MS and wellness-related research, Society staff members, and an individual with MS for developing recommendations regarding a wellness research agenda.
Method:
The members of the group engaged in focal reviews and discussions involving the state of science within three approaches for promoting wellness in MS, namely diet, exercise, and emotional wellness.
Results:
That process informed a …
A Biomechanical Comparison Of Successful And Unsuccessful Power Clean Attempts, Kristof Kipp, Carolyn M. Meinerz
A Biomechanical Comparison Of Successful And Unsuccessful Power Clean Attempts, Kristof Kipp, Carolyn M. Meinerz
Exercise Science Faculty Research and Publications
Although the power clean is an almost ubiquitous exercise in the strength and conditioning setting, relatively little is known about the biomechanics of successful and unsuccessful power clean lift attempts. The purpose of this study was to determine biomechanical differences between successful and unsuccessful power clean lift attempts in male collegiate athletes. Fifteen male lacrosse players (Age: 20.1 ± 1.2; Height: 1.78 ± 0.07 m; Body mass: 80.4 ± 8.1 kg; Relative one-repetition maximum power clean: 1.25 ± 0.13 kg/kg) were videotaped during a lifting session that required the completion of maximal effort power cleans to establish a one-repetition maximum. …
Oral Examination, Alessandro Villa, Michael J. Wells, Drore Eisen, Jeff Burgess, James J. Nordlund, Denis P. Lynch, Gary L. Stafford
Oral Examination, Alessandro Villa, Michael J. Wells, Drore Eisen, Jeff Burgess, James J. Nordlund, Denis P. Lynch, Gary L. Stafford
School of Dentistry Faculty Research and Publications
The oral cavity is the first component of the digestive tract, which is delimited by the lips anteriorly and the oropharynx posteriorly. The oral cavity functions as a protective barrier and is an essential component for speech and swallowing, mastication, digestion, and taste sensation.
The oral examination comprises a uniform and consistent inspection of the head and neck and an intraoral evaluation of the hard and soft tissues (see the images below) in conjunction with a thorough medical and dental history. The entire mouth should be inspected regardless of the patient’s chief complaint and reasons for the visit. [1 …
Expression Of Mmp-13 In Human Temporomandibular Joint Disc Derangement And Osteoarthritis, Juliano Henrique Perotto, Flavio Camejo, Andrea Doetzer, Luis Eduardo Almeida, Marina Azevedo, Marcia Olandoski
Expression Of Mmp-13 In Human Temporomandibular Joint Disc Derangement And Osteoarthritis, Juliano Henrique Perotto, Flavio Camejo, Andrea Doetzer, Luis Eduardo Almeida, Marina Azevedo, Marcia Olandoski
School of Dentistry Faculty Research and Publications
Objective: MMP-13 performs digestion of collagen, which is a primary component of the temporomandibular joint (TMJ) articular disc. This study evaluated the expression of MMP-13 in patients with anterior disc displacement with (ADDwR) and without reduction (ADDwoR), and in the presence of TMJ osteoarthrosis.
Methods: Thirty-nine human temporomandibular joint disc samples were collected and divided in two ways: ADDwR (21 samples), ADDwoR (10 samples), and a control group (8 samples); and with osteoarthrosis (10 samples) and without osteoarthrosis (29 samples). Immunostaining of the TMJ discs was statistically compared between the groups.
Results: There was no statistically significant difference for the …
Evaluation Of Glycated Albumin (Ga) And Ga/Hba1c Ratio For Diagnosis Of Diabetes And Glycemic Control: A Comprehensive Review, Sara Yazdanpanah, Mohammad Rabiee, Mohammadreza Tahriri, Mojgan Abdolrahim, Asodollah Rajab, Hossein E. Jazayeri, Lobat Tayebi
Evaluation Of Glycated Albumin (Ga) And Ga/Hba1c Ratio For Diagnosis Of Diabetes And Glycemic Control: A Comprehensive Review, Sara Yazdanpanah, Mohammad Rabiee, Mohammadreza Tahriri, Mojgan Abdolrahim, Asodollah Rajab, Hossein E. Jazayeri, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and non-ketotic hyperosmolar coma. In addition, possible long-term complications include impotence, nerve damage, stroke, chronic kidney failure, cardiovascular disease, foot ulcers, and retinopathy. Historically, universal methods to measure glycemic control for the diagnosis of diabetes included fasting plasma glucose level (FPG), 2-h plasma glucose (2HP), and random plasma glucose. However, these measurements did not provide information about glycemic control over a long period of time. To …
Immunohistochemical Analysis Of Il-1 Beta In The Discs Of Patients With Temporomandibular Joint Dysfunction, Luis Eduardo Almeida, Sean Pierce, Joseph Zacharias, William E. Cullinan, Lucia Noronha, Marcia Olandoski, Vinicius Tramontina, Carla Loreto, Rosalia Leonardi
Immunohistochemical Analysis Of Il-1 Beta In The Discs Of Patients With Temporomandibular Joint Dysfunction, Luis Eduardo Almeida, Sean Pierce, Joseph Zacharias, William E. Cullinan, Lucia Noronha, Marcia Olandoski, Vinicius Tramontina, Carla Loreto, Rosalia Leonardi
School of Dentistry Faculty Research and Publications
Purpose: Interleukin-1 beta (IL-1β) is a cytokine that participates in the regulation of immune responses and inflammatory reactions. It is hypothesized that IL-1 levels may be elevated in patients suffering from temporomandibular joint dysfunction. The purpose of this study was to determine the association of IL-1β expression with TMD using an immunohistochemical approach to evaluate the joint disc.
Materials and methods: A total of 39 human temporomandibular joint disc samples were collected, with 31 samples in the test group. Nineteen of the test group samples were from discs of patients with anterior disc displacement with reduction, and 12 …
Dental Impressions: The Digital Alternative, Gary L. Stafford
Dental Impressions: The Digital Alternative, Gary L. Stafford
School of Dentistry Faculty Research and Publications
No abstract provided.
Selecting Optimal Combinations Of Transcription Factors To Promote Axon Regeneration: Why Mechanisms Matter, Ishwariya Venkatesh, Murray G. Blackmore
Selecting Optimal Combinations Of Transcription Factors To Promote Axon Regeneration: Why Mechanisms Matter, Ishwariya Venkatesh, Murray G. Blackmore
Biomedical Sciences Faculty Research and Publications
Recovery from injuries to the central nervous system, including spinal cord injury, is constrained in part by the intrinsically low ability of many CNS neurons to mount an effective regenerative growth response. To improve outcomes, it is essential to understand and ultimately reverse these neuron-intrinsic constraints. Genetic manipulation of key transcription factors (TFs), which act to orchestrate production of multiple regeneration-associated genes, has emerged as a promising strategy. It is likely that no single TF will be sufficient to fully restore neuron-intrinsic growth potential, and that multiple, functionally interacting factors will be needed. An extensive literature, mostly from non-neural cell …
Digital Holographic Microscopy Of Phase Separation In Multicomponent Lipid Membranes, Vahideh Farzam Rad, Ali-Reza Moradi, Ahmad Darudi, Lobat Tayebi
Digital Holographic Microscopy Of Phase Separation In Multicomponent Lipid Membranes, Vahideh Farzam Rad, Ali-Reza Moradi, Ahmad Darudi, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Lateral in-homogeneities in lipid compositions cause microdomains formation and change in the physical properties of biological membranes. With the presence of cholesterol and mixed species of lipids, phospholipid membranes segregate into lateral domains of liquid-ordered and liquid-disordered phases. Coupling of two-dimensional intralayer phase separations and interlayer liquid-crystalline ordering in multicomponent membranes has been previously demonstrated. By the use of digital holographic microscopy (DHMicroscopy), we quantitatively analyzed the volumetric dynamical behavior of such membranes. The specimens are lipid mixtures composed of sphingomyelin, cholesterol, and unsaturated phospholipid, 1,2-dioleoyl-sn-glycero-3-phosphocholine. DHMicroscopy in a transmission mode is an effective tool for quantitative visualization of phase …
Impact Of Wisconsin Medicaid Policy Change On Dental Sealant Utilization, Christopher Okunseri, Elaye Okunseri, Raul I. Garcia, Cesar Gonzales, Alexis Vistocky, Aniko Szabo
Impact Of Wisconsin Medicaid Policy Change On Dental Sealant Utilization, Christopher Okunseri, Elaye Okunseri, Raul I. Garcia, Cesar Gonzales, Alexis Vistocky, Aniko Szabo
School of Dentistry Faculty Research and Publications
Background
In September 2006, Wisconsin Medicaid changed its policy to allow nondentists to become certified Medicaid providers and to bill for sealants in public health settings.
Objective
This study examined changes in patterns of dental sealant utilization in first molars of Wisconsin Medicaid enrollees associated with a policy change.
Data Source
The Electronic Data Systems of Medicaid Evaluation and Decision Support for Wisconsin from 2001 to 2009.
Study Design
Retrospective claims data analysis of Wisconsin Dental Medicaid for children aged 6-16 years.
Principal Findings
A total of 479,847 children followed up for 1,441,300 person-years with 64,546 visits were analyzed. The …
Differences In Utilization Of Dental Procedures By Children Enrolled In Wisconsin Medicaid And Delta Dental Insurance Plans, Pradeep Bhagavatula, Qun Xiang, Aniko Szabo, Fredrick Eichmiller, Christopher Okunseri
Differences In Utilization Of Dental Procedures By Children Enrolled In Wisconsin Medicaid And Delta Dental Insurance Plans, Pradeep Bhagavatula, Qun Xiang, Aniko Szabo, Fredrick Eichmiller, Christopher Okunseri
School of Dentistry Faculty Research and Publications
Background
Few studies have directly compared dental procedures provided in public and private insurance plans for enrollees living in dental health professional shortage areas (DHPSAs). We examined the rates for the different types of dental procedures received by 0–18-year-old children living in DHPSAs and non-DHPSAs who were enrolled in Medicaid and those enrolled under Delta Dental of Wisconsin (DDW) for years 2002 to 2008.
Methods
Medicaid and DDW dental claims data for 2002 to 2008 was analyzed. Enrollees were divided into DDW-DHPSA and non-DHPSA and Medicaid-DHPSA and non-DHPSA groups. Descriptive and multivariable analyses using over-dispersed Poisson regression were performed to …
Epigenetic Profiling Reveals A Developmental Decrease In Promoter Accessibility During Cortical Maturation In Vivo, Ishwariya Venkatesh, Matthew T. Simpson, Denise M. Coley, Murray G. Blackmore
Epigenetic Profiling Reveals A Developmental Decrease In Promoter Accessibility During Cortical Maturation In Vivo, Ishwariya Venkatesh, Matthew T. Simpson, Denise M. Coley, Murray G. Blackmore
Biomedical Sciences Faculty Research and Publications
Axon regeneration in adult central nervous system (CNS) is limited in part by a developmental decline in the ability of injured neurons to re-express needed regeneration associated genes (RAGs). Adult CNS neurons may lack appropriate pro-regenerative transcription factors, or may display chromatin structure that restricts transcriptional access to RAGs. Here we performed epigenetic profiling around the promoter regions of key RAGs, and found progressive restriction across a time course of cortical maturation. These data identify a potential intrinsic constraint to axon growth in adult CNS neurons. Neurite outgrowth from cultured postnatal cortical neurons, however, proved insensitive to treatments that improve …
The Role Of Spirituality And Religiosity In Persons Living With Sickle Cell Disease, Dora L. Clayton-Jones, Kristin Haglund
The Role Of Spirituality And Religiosity In Persons Living With Sickle Cell Disease, Dora L. Clayton-Jones, Kristin Haglund
College of Nursing Faculty Research and Publications
Purpose: Sickle cell disease (SCD) is a serious debilitating chronic illness, affecting approximately 90,000 Americans and millions globally. Spirituality and religiosity (S/R) may ease the burden faced by persons living with SCD. The purpose of this study was to examine the role of S/R in adolescents and adults living with SCD in the research literature.
Method: The electronic databases Cumulative Index to Nursing and Allied Health Literature, Health Source Nursing/Academic, ProQuest Health Module, PsycINFO, Medline, PubMed, and the American Theological Library Association were searched from January 1995 to December 2014.
Findings: Of the 89 studies retrieved, 11 articles between 2001 …
Weight Loss Associated With Employee Income In An Incentivized Employee Wellness Program, Jennifer T. Fink, Jennifer Rich, David R. Smith, Maharaj Singh, Kelly Sutton, George Mueller, Doug M. Ihrke, Jessica L. Skalla, Ron A. Cisler
Weight Loss Associated With Employee Income In An Incentivized Employee Wellness Program, Jennifer T. Fink, Jennifer Rich, David R. Smith, Maharaj Singh, Kelly Sutton, George Mueller, Doug M. Ihrke, Jessica L. Skalla, Ron A. Cisler
College of Nursing Faculty Research and Publications
Objective: We examined the relationship between the type of incentivized wellness program and employee weight loss and the effects of participant income. Methods: We retrospectively examined employees who participated in one of six weight loss wellness programs, which were categorized for the present analysis: reweigh/body mass index, Coaching, and Weight Watchers/Meal Replacement. Those who participated were eligible for a $350/year insurance premium discount. Results: Employees in the low-income category of $45K or less participated at a higher rate, however, did not lose as much weight as those participants in the higher income categories of $70K or more. We found a …
Short Implants Had Lower Survival Rates In Posterior Jaws Compared To Standard Implants, Gary L. Stafford
Short Implants Had Lower Survival Rates In Posterior Jaws Compared To Standard Implants, Gary L. Stafford
School of Dentistry Faculty Research and Publications
Data sources
PubMed/Medline, Embase and Cochrane Library databases supplemented by searches of the journals; Clinical Implant Dentistry and Related Research, Clinical Oral Implants Research, International Journal of Oral and Maxillofacial Implants, International Journal of Oral and Maxillofacial Surgery, Journal of Clinical Periodontology, Journal of Dentistry, Journal of Oral and Maxillofacial Surgery, Journal of Oral Implantology, Journal of Oral Rehabilitation, Journal of Periodontology, Periodontology 2000.
Study selection
Randomised controlled trials (RCTs) and prospective studies with at least ten patients, published in the last ten years that compared short and standard implants and published in English were considered.
Data extraction and …
Development Of Plga-Coated Β-Tcp Scaffolds Containing Vegf For Bone Tissue Engineering, Arash Khojasteh, Farahnaz Fahimipour, Mohamadreza Baghaban Eslaminejad, Mohammad Jafarian, Shahrbanoo Jahangir, Farshid Bastami, Mohammadreza Tahriri, Akbar Karkhaneh, Lobat Tayebi
Development Of Plga-Coated Β-Tcp Scaffolds Containing Vegf For Bone Tissue Engineering, Arash Khojasteh, Farahnaz Fahimipour, Mohamadreza Baghaban Eslaminejad, Mohammad Jafarian, Shahrbanoo Jahangir, Farshid Bastami, Mohammadreza Tahriri, Akbar Karkhaneh, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Bone tissue engineering is sought to apply strategies for bone defects healing without limitations and short-comings of using either bone autografts or allografts and xenografts. The aim of this study was to fabricate a thin layer poly(lactic-co-glycolic) acid (PLGA) coated beta-tricalcium phosphate (β-TCP) scaffold with sustained release of vascular endothelial growth factor (VEGF). PLGA coating increased compressive strength of the β-TCP scaffolds significantly. For in vitro evaluations, canine mesenchymal stem cells (cMSCs) and canine endothelial progenitor cells (cEPCs) were isolated and characterized. Cell proliferation and attachment were demonstrated and the rate of cells proliferation on the VEGF released scaffold was …
Recent Advancements In Regenerative Dentistry: A Review, Pouya Amrollahi, Brinda Shah, Amir Seifi, Lobat Tayebi
Recent Advancements In Regenerative Dentistry: A Review, Pouya Amrollahi, Brinda Shah, Amir Seifi, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Although human mouth benefits from remarkable mechanical properties, it is very susceptible to traumatic damages, exposure to microbial attacks, and congenital maladies. Since the human dentition plays a crucial role in mastication, phonation and esthetics, finding promising and more efficient strategies to reestablish its functionality in the event of disruption has been important. Dating back to antiquity, conventional dentistry has been offering evacuation, restoration, and replacement of the diseased dental tissue. However, due to the limited ability and short lifespan of traditional restorative solutions, scientists have taken advantage of current advancements in medicine to create better solutions for the oral …
Efficacy Of The Biomaterials 3 Wt%-Nanostrontium-Hydroxyapatite-Enhanced Calcium Phosphate Cement (Nanosr-Cpc) And Nanosr-Cpc-Incorporated Simvastatin-Loaded Poly(Lactic-Co-Glycolic-Acid) Microspheres In Osteogenesis Improvement, Reza Masaeli, Tahereh S. Jafarzadeh Kashi, Rassoul Dinarvand, Vahid Rakhshan, Hossein Shahoon, Behzad Hooshmand, Fatemeh Mashhadi Abbas, Majid Raz, Alireza Rajabnejad, Hossein Eslami, Kimia Khoshroo, Mohammadreza Tahriri, Lobat Tayebi
Efficacy Of The Biomaterials 3 Wt%-Nanostrontium-Hydroxyapatite-Enhanced Calcium Phosphate Cement (Nanosr-Cpc) And Nanosr-Cpc-Incorporated Simvastatin-Loaded Poly(Lactic-Co-Glycolic-Acid) Microspheres In Osteogenesis Improvement, Reza Masaeli, Tahereh S. Jafarzadeh Kashi, Rassoul Dinarvand, Vahid Rakhshan, Hossein Shahoon, Behzad Hooshmand, Fatemeh Mashhadi Abbas, Majid Raz, Alireza Rajabnejad, Hossein Eslami, Kimia Khoshroo, Mohammadreza Tahriri, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Aims
The purpose of this multi-phase explorative in vivo animal/surgical and in vitro multi-test experimental study was to (1) create a 3 wt%-nanostrontium hydroxyapatite-enhanced calcium phosphate cement (Sr-HA/CPC) for increasing bone formation and (2) creating a simvastatin-loaded poly(lactic-co-glycolic acid) (SIM-loaded PLGA) microspheres plus CPC composite (SIM-loaded PLGA + nanostrontium-CPC). The third goal was the extensive assessment of multiple in vitro and in vivo characteristics of the above experimental explorative products in vitro and in vivo (animal and surgical studies).
Methods and results pertaining to Sr-HA/CPC
Physical and chemical properties of the prepared Sr-HA/CPC were evaluated. MTT assay and …
Introducing Allergenic Food Into Infants' Diets: Systematic Review, Katelin Larson, Jessica Mclaughlin, Mallory Stonehouse, Brittany Young, Kristin Haglund
Introducing Allergenic Food Into Infants' Diets: Systematic Review, Katelin Larson, Jessica Mclaughlin, Mallory Stonehouse, Brittany Young, Kristin Haglund
College of Nursing Faculty Research and Publications
Purpose: The purpose of this systematic review was to explore the association between timing of introduction of potentially allergenic foods to infants and development of food allergies.
Methods: CINAHL, Medline, PubMed, Science Direct, and Web of Science were searched using the terms solid food, complementary food, or infant feeding combined with allergy or hypersensitivity for articles published in English in 2000 or later. Inclusion criteria were 1) primary research articles with 2) a focus on association between introduction of complementary foods including potentially allergenic foods into diets of infants less than 12 months of age and development of food allergies. …
Risk Factors Of Trastuzumab-Induced Cardiotoxicity In Breast Cancer: A Meta-Analysis, Zeeshan Jawa, Ruth M. Perez, Lydia Garlie, Maharaj Singh, Rubina Qamar, Bijoy K. Khandheria, Arshad Jahangir, Yang Shi
Risk Factors Of Trastuzumab-Induced Cardiotoxicity In Breast Cancer: A Meta-Analysis, Zeeshan Jawa, Ruth M. Perez, Lydia Garlie, Maharaj Singh, Rubina Qamar, Bijoy K. Khandheria, Arshad Jahangir, Yang Shi
College of Nursing Faculty Research and Publications
Background:
Trastuzumab targets the human epidermal growth factor receptor 2 oncogene and in combination with first-line therapy results in significantly improved survival outcomes and has thus become standard of care in both adjuvant and metastatic settings. While it is estimated that 1% to 4% of patients treated with trastuzumab will develop heart failure and ∼10% will experience a reduction in left ventricular ejection fraction (LVEF), the patient risk factors associated with trastuzumab-induced cardiotoxicity (TIC) are unclear. This meta-analysis aims to consolidate previously published data to identify the risk factors most likely leading to TIC.
Methods:
A search of the MEDLINE …
Autism Spectrum Disorder And The Child's Weight–Related Behaviors: A Parents' Perspective, Michele Polfuss, Norah L. Johnson, Susan A. Bonis, Fallon Apollon, Kathleen Sawin
Autism Spectrum Disorder And The Child's Weight–Related Behaviors: A Parents' Perspective, Michele Polfuss, Norah L. Johnson, Susan A. Bonis, Fallon Apollon, Kathleen Sawin
College of Nursing Faculty Research and Publications
Purpose
To explore parent perspectives of how the attributes of their child's autism spectrum disorder(ASD) impact nutrition, physical activity, screen time behaviors and risk for obesity. Secondarily, we examined the parent's perception of the healthcare providers (HCP) influence on these weight-related behaviors.
Design and method
We conducted and audio-recorded telephone interviews with parents of children with ASD (n = 8) using a structured question guide. Data were transcribed and thematic analysis was conducted. Issues surrounding weight-related behaviors and parental strategies used were reported.
Results
Two overarching themes with eight subthemes emerged: (1) Challenges related to features of ASD (subthemes included …
Patient/Family Education For Newly Diagnosed Pediatric Oncology Patients, Wendy Landier, Joann Ahern, Lamia P. Barakat, Smita Bhatia, Kristin M. Bingen, Patricia G. Bondurant, Susan L. Cohn, Sarah K. Dobrozsi, Maureen Haugen, Ruth Anne Herring, Mary C. Hooke, Melissa Martin, Kathryn Murphy, Amy R. Newman, Cheryl C. Rodgers, Kathleen S. Ruccione, Jeneane Sullivan, Marianne E. Weiss, Janice Withycombe, Lise Yasui, Marilyn Hockenberry
Patient/Family Education For Newly Diagnosed Pediatric Oncology Patients, Wendy Landier, Joann Ahern, Lamia P. Barakat, Smita Bhatia, Kristin M. Bingen, Patricia G. Bondurant, Susan L. Cohn, Sarah K. Dobrozsi, Maureen Haugen, Ruth Anne Herring, Mary C. Hooke, Melissa Martin, Kathryn Murphy, Amy R. Newman, Cheryl C. Rodgers, Kathleen S. Ruccione, Jeneane Sullivan, Marianne E. Weiss, Janice Withycombe, Lise Yasui, Marilyn Hockenberry
College of Nursing Faculty Research and Publications
There is a paucity of data to support evidence-based practices in the provision of patient/family education in the context of a new childhood cancer diagnosis. Since the majority of children with cancer are treated on pediatric oncology clinical trials, lack of effective patient/family education has the potential to negatively affect both patient and clinical trial outcomes. The Children’s Oncology Group Nursing Discipline convened an interprofessional expert panel from within and beyond pediatric oncology to review available and emerging evidence and develop expert consensus recommendations regarding harmonization of patient/family education practices for newly diagnosed pediatric oncology patients across institutions. Five broad …
Interprofessional Health Team Communication About Hospital Discharge: An Implementation Science Evaluation Study, Sarah J. Bahr, Danielle M. Siclovan, Kristi Opper, Joseph Beiler, Kathleen Bobay, Marianne E. Weiss
Interprofessional Health Team Communication About Hospital Discharge: An Implementation Science Evaluation Study, Sarah J. Bahr, Danielle M. Siclovan, Kristi Opper, Joseph Beiler, Kathleen Bobay, Marianne E. Weiss
College of Nursing Faculty Research and Publications
The Consolidated Framework for Implementation Research guided formative evaluation of the implementation of a redesigned interprofessional team rounding process. The purpose of the redesigned process was to improve health team communication about hospital discharge. Themes emerging from interviews of patients, nurses, and providers revealed the inherent value and positive characteristics of the new process, but also workflow, team hierarchy, and process challenges to successful implementation. The evaluation identified actionable recommendations for modifying the implementation process.
Development And Psychometric Analysis Of The Patient Perceptions Of Patient-Empowering Nurse Behaviours Scale (Pppnbs), Teresa Jerofke-Owen, Marianne E. Weiss
Development And Psychometric Analysis Of The Patient Perceptions Of Patient-Empowering Nurse Behaviours Scale (Pppnbs), Teresa Jerofke-Owen, Marianne E. Weiss
College of Nursing Faculty Research and Publications
Aim
To (1) develop and psychometrically test the Patient Perceptions of Patient-Empowering Nurse Behaviours Scale, which measures patient perceptions of empowering nurse behaviours during hospitalization; and (2) refine to a shorter, more useful form, for measurement in clinical settings.
Background
Although patient empowerment has been promoted as a way to engage patients in chronic illness care, there is not a measure reported by patients as recipients of empowering nurse behaviours during hospitalization.
Design
Psychometric evaluation of construct and predictive validity, reliability and item reduction.
Method
Data gathered during hospitalization and six weeks postdischarge between April 2012 - August 2014 were …