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Full-Text Articles in Medicine and Health Sciences

Quantifying The Concentration Of 33-Mer In Wheat Flour, Abigail E. Rivas, Kaylee A. Howell, Robert Paris Apr 2020

Quantifying The Concentration Of 33-Mer In Wheat Flour, Abigail E. Rivas, Kaylee A. Howell, Robert Paris

Scholars Symposium

Celiac Disease is a type IV hypersensitive response to gluten caused by HLA-DQ2 or HLA-DQ8 T-cell presentation, initiating destruction of intestinal epithelial cells. Currently, the only remedy for those suffering from celiac disease is the complete elimination of all gluten from the diet. Studies indicate that an indigestible fragment of the gluten molecule, alpha-gliadin subcomponent 33-mer, rich in proline and glutamine, is responsible for the hypersensitivity response. Determination of 33-mer concentration in wheat lines could be beneficial to the future development of wheat lines with reduced 33-mer concentration. In this study, gliadin protein from wheat flour was extracted and separated …


Inter-Disciplinary Team Work With Substance Use And Recovery, Sandra Wagner, Meghan Mosser, Marc Sweeney, Val Czyzewksi, Cynthia Yu Apr 2020

Inter-Disciplinary Team Work With Substance Use And Recovery, Sandra Wagner, Meghan Mosser, Marc Sweeney, Val Czyzewksi, Cynthia Yu

Scholars Symposium

Purpose. Homeless women who struggle with substance use disorder have a difficult time finding inpatient treatment. Her Story provides these women with housing, support and health care until they are connected to inpatient rehabilitation. Upon graduating from inpatient rehabilitation, continuity of care and support are lacking. The collaborative practice model aims to fill the gaps in health care coordination and community involvement before and after inpatient rehabilitation for women in recovery.

Methods. Multiple disciplines including social work, occupational therapy and pharmacy are working together to provide women with the opportunity to take control of their care. Through an innovative patient-centered …


Probiotic Use And Their Effect On Ibs Symptoms: A Review Of Literature, Emma A. Nice, Brianna M. Noller, Janae E. Coin Apr 2019

Probiotic Use And Their Effect On Ibs Symptoms: A Review Of Literature, Emma A. Nice, Brianna M. Noller, Janae E. Coin

The Research and Scholarship Symposium (2013-2019)

Aim: Probiotics are an attractive therapy for patients dealing with irritable bowel syndrome (IBS) in light of decreased financial costs, fewer medications, and a more natural approach. In this review of literature our purpose was to answer the following PICO question: “In adults with IBS, how does supplemental probiotic use compared to no probiotic use affect IBS symptoms?” Methods: In our review of the literature, the databases searched were CINAHL, MEDLINE, Cochrane, PubMed, Google Scholar, and Onesearch from the years 2008-2018; from which we found ten articles published within the last six years. Results: Seventy percent of the articles reviewed …


Using Ct Scans To Describe An Allosaurus Skull (Dinosauria: Theropoda), Jordan C. Oldham Apr 2019

Using Ct Scans To Describe An Allosaurus Skull (Dinosauria: Theropoda), Jordan C. Oldham

The Research and Scholarship Symposium (2013-2019)

In 2001, an Allosaurus skull (CMP 279) was discovered in the Skull Creek Basin in Moffat County, Colorado. The skull is one of the most complete for the species and even contains the hyoid bones, which are usually not present. The skull is now permanently mounted, for display purposes, thus making the study of the individual bones difficult for producing a paleo-anatomical description. Computed Tomography (CT) scans of CMP 279 were created in 2017 and then made available for this study in 2019. CT scans are being used to investigate internal anatomy of skulls such as the endocranial cavity, sinuses, …


The Efficacy Of A Self-Care Training Program For Cedarville University Nursing Students, Leah Vance Sr., Kimberlyn Wideman Sr., Kylee Metzger Sr. Apr 2019

The Efficacy Of A Self-Care Training Program For Cedarville University Nursing Students, Leah Vance Sr., Kimberlyn Wideman Sr., Kylee Metzger Sr.

The Research and Scholarship Symposium (2013-2019)

Problem: Cedarville university nursing students are likely to experience stressful work environments and traumatic events. Wentzel (2017) reports that nurses often encounter critical incidents. Exposure to critical incidents can affect the mental health of nurses and lead to secondary or vicarious trauma (Mayer, 2018). Students entering the nursing profession need to develop self-care practices to enhance productivity and maintain their emotional health as they provide care to patients (Boyle, 2011). The current study seeks to help Cedarville nursing students develop better self-care practices. Research Question: Does a self-care training program decrease the level of stress in Cedarville nursing students? Method:This …


Comparing The Effects Of Tissue Flossing And Instrument Assisted Soft Tissue Mobilization On Ankle Dorsiflexion, Sean Carlson, Garrett Rife, Zachary Williams Apr 2019

Comparing The Effects Of Tissue Flossing And Instrument Assisted Soft Tissue Mobilization On Ankle Dorsiflexion, Sean Carlson, Garrett Rife, Zachary Williams

The Research and Scholarship Symposium (2013-2019)

Purpose: The purpose of this study is to evaluate the claimed effects of a new technique called Tissue Flossing and compare those effects with Instrument Assisted Soft Tissue Mobilization, or IASTM. Background: Tissue flossing is a relatively new technique that utilizes a large rubber band that is wrapped around the involved joint. Once applied, range of motion exercises are completed, and the band is removed. The goal is to increase joint range of motion. IASTM involves using a specialized tool to scrape an effected muscle or tendon of the body. The goal is to reduce any adhesions or scar tissue …


Plantar Fasciitis: Steroid Injections Vs. Prp Injections, Abigail R. Snyder Apr 2019

Plantar Fasciitis: Steroid Injections Vs. Prp Injections, Abigail R. Snyder

The Research and Scholarship Symposium (2013-2019)

Plantar fasciitis is a common complaint of many people at some point throughout their lifetime. The aim of this presentation is to provide an in-depth clinical review and comparison of two treatment options for chronic plantar fasciitis; steroid injections and platelet-rich plasma injections. Acute cases of plantar fasciitis are caused by inflammation of the plantar fascia of the foot. Therefore, common initial treatments include stretching of the calf muscle, stretching of the plantar fascia itself, rest, use of night splints, and orthotics. However, for some people these conservative treatments fail. In those situations, the pain is assumed to be caused …


Effects Of Warm Tub Immersion Versus Cold Tub Immersion To Relieve Delayed Onset Muscle Soreness In Division 2 Collegiate Baseball Players, Erin Ackerson, Kelsey Caldwell, Lindsey Ford Apr 2019

Effects Of Warm Tub Immersion Versus Cold Tub Immersion To Relieve Delayed Onset Muscle Soreness In Division 2 Collegiate Baseball Players, Erin Ackerson, Kelsey Caldwell, Lindsey Ford

The Research and Scholarship Symposium (2013-2019)

In our study we looked at the effects of warm tub immersion versus cold tub immersion to relieve delayed onset muscle soreness (DOMS) in Division II collegiate athletes. We chose to research this topic because we are a group of three senior Athletic Training students and have seen the use of Cold Tub Immersion in everyday modality interventions to treat DOMS. In recent years there has been controversy over if Cold Tub Immersion is best patient care or if possibly implementing Warm Tub Immersion would be more effective in treating DOMS. Although there is a vast amount of literature examining …


The Youngest Victims Of The Opioid Epidemic, Katelyn E. Miller, Abby Reed Apr 2018

The Youngest Victims Of The Opioid Epidemic, Katelyn E. Miller, Abby Reed

The Research and Scholarship Symposium (2013-2019)

When babies are born to opioid-addicted mothers, they often develop Neonatal Abstinence Syndrome (NAS). NAS is characterized by symptoms associated with abrupt opioid withdrawal (“Neonatal Abstinence”, 2015). By preventing NAS in babies before they are born and properly caring for a baby with NAS after birth, we will aim to decrease the incidence of this condition and as its harmful effects in the lives of babies. In Ohio, there are many neonates suffering from NAS. The rates for babies born with NAS have quadrupled since 2011 when 2.2 out of every 1000 babies had NAS to 2015, where 12.3 out …


Quality Of Life Among Breast Cancer Survivors: A Review Of Literature, Autumn Sue Hankins, Kaitlyn Elizabeth Pees, Mikalyn Marie Heidish Apr 2018

Quality Of Life Among Breast Cancer Survivors: A Review Of Literature, Autumn Sue Hankins, Kaitlyn Elizabeth Pees, Mikalyn Marie Heidish

The Research and Scholarship Symposium (2013-2019)

Background: Each year 124.9 per 100,000 women are diagnosed with breast cancer worldwide (National Cancer Institute, n.d.). While it is a serious diagnosis, with modern screening and early detection, survivorship is higher than ever before. The current five-year survival rate for women diagnosed with cancer worldwide is 89.7% (National Cancer Institute, n.d.). The emphasis of this literature review is to address the perceived quality of life of this population. Purpose: The purpose of this literature review was to determine how women who have survived a diagnosis of breast cancer perceive their quality of life (QOL). Methods: This review examined research …


Pediatric Experiences Of Ptsd Related To Natural Disasters, Victoria J. Denen, Julianna H. Ruckersfeldt, Wyatt S. Kyser Apr 2018

Pediatric Experiences Of Ptsd Related To Natural Disasters, Victoria J. Denen, Julianna H. Ruckersfeldt, Wyatt S. Kyser

The Research and Scholarship Symposium (2013-2019)

Between 1994 and 2013, the International Disaster Database recorded 6,873 natural disasters worldwide, which claimed 1.35 million lives or almost 68,000 lives on average each year. In addition, an average of 218 million people were affected by natural disasters per year during this 20-year period (Centre for Research on the Epidemiology of Disasters, 2015). All disasters have the potential to affect psychological health (U.S. Department of Veteran Affairs, 2016) and children are especially vulnerable. The purpose of this review of literature was to answer the question, “How do children and adolescents who have survived a form of severe natural disaster …


The Role Of Athletic Identity In The Etiology Of Stress Fractures In Collegiate Runners, Leah Mae Reeder, Kurt D. Beachy Apr 2018

The Role Of Athletic Identity In The Etiology Of Stress Fractures In Collegiate Runners, Leah Mae Reeder, Kurt D. Beachy

The Research and Scholarship Symposium (2013-2019)

Background: The efficacy of the Athletic Identity Measurement Scale (AIMS) and Compulsive Exercise Test (CET) as a screening tool for identifying runners who are at high-risk for incurring a stress fracture. A screening tool that incorporates both physical and psychological risk factors may be key in preventing stress fracture incidence in collegiate runners. Methods: A descriptive survey was designed and filled out by collegiate runners to collect information about various well-known risk factors as well as age, gender, anthropometric measures, injury history, competitive training years, weekly training mileage, and history of disordered eating. The AIMS and CET were included in …


The Prevalence Of Psychological Side Effects Of Concussions In Division Ii And Iii Athletes In Ohio, Ellen P S Dixon, Laura J. Weaver, Michael Weller Apr 2018

The Prevalence Of Psychological Side Effects Of Concussions In Division Ii And Iii Athletes In Ohio, Ellen P S Dixon, Laura J. Weaver, Michael Weller

The Research and Scholarship Symposium (2013-2019)

Background: Concussions are becoming an epidemic as millions of athletes are diagnosed with concussions each year. Concussions are not homogenous injuries and should be managed uniquely. Often health care providers focus on the physical side effects of concussions and ignore the psychological side effects. Methods: In order to determine the prevalence of psychological side effects resulting from concussions and the frequency of ATCs or team physicians managing their psychological symptoms we sent out a survey. The survey included seventeen questions related to demographics and concussion symptoms that were sent to Division II and III athletes in Ohio over the age …


Common Spine Boarding Practices In The Athletic Setting: A Survey Of Athletic Trainers And Athletic Training Students, Jamie Lynne Field, Michael S. Weller Apr 2018

Common Spine Boarding Practices In The Athletic Setting: A Survey Of Athletic Trainers And Athletic Training Students, Jamie Lynne Field, Michael S. Weller

The Research and Scholarship Symposium (2013-2019)

Background: The prehospital care of spinal injuries is a debated topic amongst those in the area of emergency medicine. There is great risk for a spinal cord injury following a direct trauma.1 This risk is increased after medical professionals have come to the aid of the victim, increasing risk for further injury from 1.8%-10% in a hospital and up to 25% at the injury scene.1 Past research has shown the need for improved care and education of spinal injuries. There are many areas of dispute under the general topic of spine boarding. Methods: The researcher drafted a two part survey …


3d Printed Pla Scaffolds To Promote Healing Of Large Bone Defects, Jacob W. Cole, Tiera Martinelli, Mitchell T. Ryan, Sarah G. Seman, Daniel Sidle, Stephen R. Smith, Rocco J. Rotello, Timothy L. Norman Apr 2018

3d Printed Pla Scaffolds To Promote Healing Of Large Bone Defects, Jacob W. Cole, Tiera Martinelli, Mitchell T. Ryan, Sarah G. Seman, Daniel Sidle, Stephen R. Smith, Rocco J. Rotello, Timothy L. Norman

The Research and Scholarship Symposium (2013-2019)

One challenge modern medicine faces is the ability to repair large bone defects and stimulate healing. Small defects typically heal naturally, but large bone defects do not and current solutions are to replace the missing tissue with biologically inert materials such as titanium. This limits the amount of bone healing as the defect is not repaired but rather replaced. The focus of our research is to develop a method of using 3D printing to create biodegradable scaffolds which promote bone in-growth and replacement. To accomplish this we used poly lactic acid (PLA) filament and a desktop 3D printer. To promote …


The Effect Of Kinship Foster Care Compared To Non-Kinship Foster Care On Resiliency, Heidi M. Vizino, Alyssa B. Bergthold Apr 2018

The Effect Of Kinship Foster Care Compared To Non-Kinship Foster Care On Resiliency, Heidi M. Vizino, Alyssa B. Bergthold

The Research and Scholarship Symposium (2013-2019)

An estimated 40% to 60% of children in foster care have clinically significant emotional or behavioral problems (US Public Health Service, 2000). Children in foster care experience a range of complex psychosocial issues due to a loss of stability in a foundational biological family unit. Research shows that placement type may have an impact on a child’s socioemotional resiliency and level of access to needed mental health services (Lynch, 2011; Smithgall, Yang, & Weiner 2013; Winokur, 2014). The purpose of this literature review was to evaluate the effect of foster home placement type, specifically kinship foster care compared to non-kinship …


The Engineering Of A Microscale Niche To Test A Novel Anti-Cancer Agent, Dominic M. Halsmer, William Ranahan, Alexander C. Mills Jun 2017

The Engineering Of A Microscale Niche To Test A Novel Anti-Cancer Agent, Dominic M. Halsmer, William Ranahan, Alexander C. Mills

Christian Engineering Conference

Cutting-edge biomedical research often relies on innovative tools from the field of engineering. Some of these tools are designed to investigate or probe a niche, analyzing its characteristics and affordances. Other devices are engineered to create a niche in which a specific, unique interaction can take place, while the outcomes are carefully monitored. This paper will focus of the latter and, more specifically, the production of a niche for inducing promising interaction between cancer cells and certain types of fungi. Preliminary research suggests that when maintained in close proximity to breast cancer cells, mushroom mycelia secrete compounds which trigger the …


The Science Of Singing: A Voice Lesson From Anatomy And Physiology, Gracie Bennett Apr 2017

The Science Of Singing: A Voice Lesson From Anatomy And Physiology, Gracie Bennett

The Research and Scholarship Symposium (2013-2019)

The voice is the oldest instrument in existence. Throughout its history, there have been many vocal performances practices. The purpose of my research is to show the correlation between modern vocal practices and the current medical technology available to help us understand the physiology of the voice. I am studying and analyzing the vocal performance and pedagogical practices from the early church to present day. I want to know why these vocal strategies have changed over time. There have been several different schools of thinking in regards to vocal practices. From the Italian style bel canto singing that was widely …


Patients’ Perceptions Of Pharmacist Intervention Through Pre-Screened Medication Therapy Management Service, Danielle E. Baker, Colin J. Behm, Bryan Feldmann, Jeremy Flikkema, Thaddeus T. Franz Apr 2017

Patients’ Perceptions Of Pharmacist Intervention Through Pre-Screened Medication Therapy Management Service, Danielle E. Baker, Colin J. Behm, Bryan Feldmann, Jeremy Flikkema, Thaddeus T. Franz

The Research and Scholarship Symposium (2013-2019)

Background: The continued challenge of time commitment in a community pharmacy setting is reported by pharmacists as the single largest setback in providing quality patient care. Additionally, when efforts are made by pharmacists to intervene on a patient’s therapy through medication therapy management (MTM), patient “no shows” further challenge an already busy community pharmacy world. Many studies show the value of a pharmacist-patient relationship. However, continued barriers prevent the value of this relationship to take full effect. While numerous methods of comprehensive medication review take place, the issue of establishing a model that best suits the needs of community pharmacy …


The Effectiveness Of Cognitive Behavioral Therapy On Management Of Symptoms In Rheumatoid Arthritis Patients, Miriam J. Morris, Bernadette F. Rowe, Jessica L. Stauf Apr 2017

The Effectiveness Of Cognitive Behavioral Therapy On Management Of Symptoms In Rheumatoid Arthritis Patients, Miriam J. Morris, Bernadette F. Rowe, Jessica L. Stauf

The Research and Scholarship Symposium (2013-2019)

Objectives: To carry out a systematic review of literature examining the effectiveness of cognitive behavioral therapy (CBT) alongside pharmacological treatment of rheumatoid arthritis (RA) symptoms compared to pharmacological treatments (standard care) without CBT.

Methods: The Iowa Model of Evidence-Based Practice to Promote Quality Care was used as the theoretical framework for this review of literature. Databases utilized: CINAHL, OneSearch, PubMed, and MedLine. The inclusion criteria for this search were: CBT as an intervention, articles published within 2006-2016, and English full text articles.

Exclusion criteria were: participants less than 18 years of age, interventions other than CBT, or any other type …


E,E-Farnesol Inhibits Swarming Motility In Burkholderia Cepacia Through Rhamnolipid Production, Stephanie E. Nicholls, Alayna N. Sanderson, Andrea P. Schwartz, Lauren E. Ward, Jessica N. Weisensee, Molly Yandrofski, Tracy L. Collins Apr 2017

E,E-Farnesol Inhibits Swarming Motility In Burkholderia Cepacia Through Rhamnolipid Production, Stephanie E. Nicholls, Alayna N. Sanderson, Andrea P. Schwartz, Lauren E. Ward, Jessica N. Weisensee, Molly Yandrofski, Tracy L. Collins

The Research and Scholarship Symposium (2013-2019)

Burkholderia cepacia and Candida albicans both exhibit cell-to-cell communication through the use of quorum-sensing molecules (QSM) known as autoinducers. E,E-farnesol is a QSM produced by C. albicans which regulates its conversion from yeast to mycelium. Because there is a positive correlation between the presence of B. cepacia and C. albicans in the lungs of individuals with cystic fibrosis (CF), we examined whether E,E-farnesol had an effect on swarming motility in B. cepacia. Swarming motility was inhibited when B. cepacia was exposed to 250 µM of E,E-farnesol. In addition, there was a 26.8% decrease in rhamnolipid production when cells were grown …


2017 Symposium Overview, Cedarville University Apr 2017

2017 Symposium Overview, Cedarville University

The Research and Scholarship Symposium (2013-2019)

Click the "Download" button in the top right corner to view the abstract booklet.


Employing “Fdalabel” Database To Extract Pharmacogenomics Information From Fda Drug Labeling To Advance The Study Of Precision Medicine, Ryley B. Uber, Hong Fang, Zhichao Liu, Joshua Xu, Shraddha Thakkar, Shashi Amur, Padmaja Mummaneni, Minjun Chen, Baitang Ning, Steve Harris, Guangxu Zhou, Leihong Wu, Paul Howard, Weida Tong Apr 2017

Employing “Fdalabel” Database To Extract Pharmacogenomics Information From Fda Drug Labeling To Advance The Study Of Precision Medicine, Ryley B. Uber, Hong Fang, Zhichao Liu, Joshua Xu, Shraddha Thakkar, Shashi Amur, Padmaja Mummaneni, Minjun Chen, Baitang Ning, Steve Harris, Guangxu Zhou, Leihong Wu, Paul Howard, Weida Tong

The Research and Scholarship Symposium (2013-2019)

Pharmacogenomics (PGx) focuses on how genomics and genetic variants (inherited and acquired) affect drug response. A better understanding of the association between genetic markers and individual phenotypes may improve therapy by enhancing drug efficacy, safety, and advance precision medicine. The FDALabel database (https://rm2.scinet.fda.gov/druglabel/#simsearch-0) was developed from the FDA's Structured Product Labeling (SPL) repository to allow users to perform full-text and customizable searches of the labeling section {e.g. Boxed Warning, Warning and Precautions, Adverse Reaction (AR) sections}. In this study, 48 known biomarkers were used to query PGx relevant contents from the FDALabel database, including Indication, Clinical Pharmacology, Clinical Studies, and …


Stress And Sleep Quality: Mediating Effects Of Social Support, Felisha L. Younkin, Elizabeth A. Axtell, Chelsea R. Anderton Apr 2017

Stress And Sleep Quality: Mediating Effects Of Social Support, Felisha L. Younkin, Elizabeth A. Axtell, Chelsea R. Anderton

The Research and Scholarship Symposium (2013-2019)

Stress is defined as the “nonspecific response of the body to any demand made upon it” (Kohn & Frazer, 1986). Stress is among the top five threats to academic performance among college students (Pettit & DeBarr, 2011). The purpose of the study was to investigate whether stress affects perceived sleep quality, as mediated by social support, and to determine whether stress levels vary based on academic major. Using ANOVA in SPSS 24, we tested three hypotheses: stress and sleep quality are negatively correlated, social support mediates the relationship between stress and sleep quality, and stress levels will vary by academic …


Relationship Quality Of Siblings Attending The Same University, Ashley M. Belles Apr 2017

Relationship Quality Of Siblings Attending The Same University, Ashley M. Belles

The Research and Scholarship Symposium (2013-2019)

This phenomenological qualitative study explores the relationship quality of siblings who both attend Cedarville University. This study seeks to identify commonalities and key components to close sibling relationships. The desire to attend the same school, or remain close to a sibling was explored, as well. Questions specifically focused on family life growing up, and current family life, while attending Cedarville University. These questions were designed to gain background information, while also gaining insight to current relationship quality and conflict. Some themes that have emerged are similarities in sibling roles based on birth order, and influencing each other in making morally …


Developmental Results Of Military Kids’ Upbringing: A Qualitative Analysis, Michael W. Firmin, Taylor E. Hobbs, Aubrey Gillette, Hannah Grammer Apr 2017

Developmental Results Of Military Kids’ Upbringing: A Qualitative Analysis, Michael W. Firmin, Taylor E. Hobbs, Aubrey Gillette, Hannah Grammer

The Research and Scholarship Symposium (2013-2019)

In the present qualitative study, researchers focused on the similarities among college-aged military kids due to similar upbringings and shared experiences. The study was conducted through semi-structured interviews in which participants were asked to draw conclusions between past experiences and present attitudes. Researchers found major themes during the interviews and the themes of military pride, respect, and acculturation are the focus of the current presentation.


The Effects Of Square-Stepping Exercise On Risk Of Falling And Balance In Senior Adults, Grace A. Miorelli, Michaela Nelson, Elizabeth A. Sled, Benjamin T. Massa, Mackenzi J. Clemens, Hope E. Mccoll, April D. Crommett Apr 2017

The Effects Of Square-Stepping Exercise On Risk Of Falling And Balance In Senior Adults, Grace A. Miorelli, Michaela Nelson, Elizabeth A. Sled, Benjamin T. Massa, Mackenzi J. Clemens, Hope E. Mccoll, April D. Crommett

The Research and Scholarship Symposium (2013-2019)

As people age, their body systems gradually deteriorate. Muscle function and the vestibular system slowly deteriorate leading to lower body instability. Older adults who struggle with dizziness and imbalance are more prone to falling. Dizziness and imbalance cause falls, and falls are the leading cause of hospitalization and accidental death in older adults (Shinichi & Tatsuya, 2015). It is possible to prevent and reduce the risk of falls through balance training. It is crucial that older adults take the steps needed to improve their balance and therefore reduce their risk of falling. PURPOSE: To evaluate the effect of a 10-week …


Correlation Study: Student Success In Biochemistry As A Prerequisite For Integrated Pharmacology And Medicinal Chemistry, April Filter, Stacy Lin, Sydney Schultz, Rachel Anderson, Tori Twinem, Denise S. Simpson, Melissa J. Beck Apr 2017

Correlation Study: Student Success In Biochemistry As A Prerequisite For Integrated Pharmacology And Medicinal Chemistry, April Filter, Stacy Lin, Sydney Schultz, Rachel Anderson, Tori Twinem, Denise S. Simpson, Melissa J. Beck

The Research and Scholarship Symposium (2013-2019)

Background

A rise in new schools of pharmacy has led to implementation of new curriculums. Pharmacy schools must adhere to standards set by the Accreditation Council of Pharmacy Education in order to provide knowledge of foundational sciences and prepare pharmacy students for the future. Prerequisites are typically foundational science courses taken early in the program so that students have the knowledge necessary to be excellent pharmacists. Within the Cedarville University School of Pharmacy, Biochemistry is a prerequisite course for Integrated Medicinal Chemistry and Pharmacology (PCoMedChem).

Objectives

The goal of this study is to determine if Biochemistry should remain a prerequisite …


The Effect Of Photoactivated Tmp On Burkholderia Cepacia Biofilms, Reyna G. Osorio, Chandra N. Swiech, Tracy L. Collins Apr 2017

The Effect Of Photoactivated Tmp On Burkholderia Cepacia Biofilms, Reyna G. Osorio, Chandra N. Swiech, Tracy L. Collins

The Research and Scholarship Symposium (2013-2019)

Burkholderia cepacia is an opportunistic pathogen that causes infections in immunocompromised individuals such as cystic fibrosis patients. B. cepacia infections are typically characterized by the formation of complex communities of cells known as biofilms. Because B. cepacia biofilms are difficult to eradicate using antibiotics, it is important to pursue alternative treatment methods. Photodynamic therapy (PDT) is a type of therapy that uses light, a photosensitizer, and oxygen to elicit cell death through the production of reactive oxygen species. PDT has been shown in previous studies to be successful in killing both Pseudomonas aeruginosa and Staphylococcus aureus. In this study, we …


The Effect Of Luteolin On Human Glioblastoma, David M. Anson, Samson Amos, Robert L. Paris, Denise S. Simpson Apr 2016

The Effect Of Luteolin On Human Glioblastoma, David M. Anson, Samson Amos, Robert L. Paris, Denise S. Simpson

The Research and Scholarship Symposium (2013-2019)

Glioblastoma multiforme (GBM) is widely recognized as the most common and lethal of the malignant gliomas. Few effective therapeutic treatments are available as five-year survival rates of diagnosed individuals are less than five percent. Luteolin, a common flavonoid found in a variety of fruits and vegetables, has demonstrated significant promise in combating cancers of the breast, colon, liver, lung, and bone. In this study, we investigated the effects of luteolin on glioblastoma multiforme cell lines U-251, U-87, and U-1242. Cell viability was assessed using cell count with trypan blue exclusion and MTT assays. Results revealed that luteolin reduces GBM cell …