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Articles 5461 - 5490 of 321937
Full-Text Articles in Medicine and Health Sciences
Assessing The Preparedness Of New Graduate Physical Therapists For Primary Care Physical Therapy Roles, Hannah Ellen Snobeck, Olivia Mavis Manuel, Rachel Jean Dukart, Samantha Marie Krogfoss, Logan Nicole Redding, Haley Paige Hase, Reese Paige Richards
Assessing The Preparedness Of New Graduate Physical Therapists For Primary Care Physical Therapy Roles, Hannah Ellen Snobeck, Olivia Mavis Manuel, Rachel Jean Dukart, Samantha Marie Krogfoss, Logan Nicole Redding, Haley Paige Hase, Reese Paige Richards
Physical Therapy Scholarly Projects
Background and Purpose: The growing shortage of primary care providers in the United States has led to increased discussion about expanding the role of physical therapists (PTs) in primary care. Physical therapists have advanced diagnostic and musculoskeletal expertise that helps them succeed in these roles. This study aimed to assess how new graduates perceive their readiness to practice as primary care providers and to identify the education and experiential factors that shape this.
Methods: Using a qualitative research design guided by self-perception theory, semi-structured interviews were conducted with three physical therapists who graduated between 2022 and 2024. Participants were asked …
Electromyography (Emg) Of Lower Extremity Muscles During The Spanish Squat In Varied Foot Positions, Matthew Feddema, Jake Graf, Jenna Hildebrant, Allison Jepson, Jake Marciniak, Benjamin Oie
Electromyography (Emg) Of Lower Extremity Muscles During The Spanish Squat In Varied Foot Positions, Matthew Feddema, Jake Graf, Jenna Hildebrant, Allison Jepson, Jake Marciniak, Benjamin Oie
Physical Therapy Scholarly Projects
Background: Knee injuries are among the most common sports-related injuries, often linked to weakness or imbalance in the quadriceps and gluteal muscles. Squat variations are frequently prescribed in rehabilitation to strengthen these muscle groups and enhance knee and hip stability. The Spanish squat (SS) has shown to be effective for increasing quadriceps activation while reducing joint stress. However, limited research has examined how different stance widths during Spanish squats may effect lower extremity muscle activation.
Purpose: This study aimed to compare surface electromyography (EMG) activity of selected lower extremity muscles during Spanish squat variations (narrow, shoulder-width, and wide stances) and …
Minimal Change Disease Following B-Cell Maturation Antigen-Directed Chimeric Antigen Receptor T-Cell Therapy, Kiran Shivaraj, Omar Mamlouk, Amanda Tchakarov, Krina Patel, Ala Abudayyeh
Minimal Change Disease Following B-Cell Maturation Antigen-Directed Chimeric Antigen Receptor T-Cell Therapy, Kiran Shivaraj, Omar Mamlouk, Amanda Tchakarov, Krina Patel, Ala Abudayyeh
Faculty, Staff and Student Publications
Acute kidney injury (AKI) is a well-recognized complication of chimeric antigen receptor (CAR) T-cell therapy, typically attributed to cytokine release syndrome and acute tubular injury. However, glomerular disease post CAR-T cell is rare. We report a case of minimal change disease presenting with AKI and nephrotic-range proteinuria 3 weeks after B-cell maturation antigen-directed CAR-T cell therapy, ciltacabtagene autoleucel, in a patient with relapsed refractory multiple myeloma. The kidney biopsy revealed diffuse podocyte foot process effacement and a predominance of CD4+ T cells with potential on-target, off-tumor effect of B-cell maturation antigen-directed CAR-T cell therapy, leading to podocyte injury. The patient …
Transcranial Doppler Ultrasound Velocity Measurements In Children With Sickle Cell Disease In Kenya, Catherine Mwalimu, Oscar Odhiambo, Elaine Mashisia, Teresa Mwanja, Allan Ade, Maria De Vita, Katherine Oyieke, Pauline Samia, Fenella Kirkham, Samson Gwer
Transcranial Doppler Ultrasound Velocity Measurements In Children With Sickle Cell Disease In Kenya, Catherine Mwalimu, Oscar Odhiambo, Elaine Mashisia, Teresa Mwanja, Allan Ade, Maria De Vita, Katherine Oyieke, Pauline Samia, Fenella Kirkham, Samson Gwer
Paediatrics and Child Health, East Africa
Background Sickle cell disease (SCD) is the most common inherited haemoglobinopathy and poses a high public health burden in Sub-Saharan Africa. Children with sickle cell anaemia are at a highrisk of ischemic stroke, and transcranial Doppler (TCD) ultrasonography helps identify those at highest risk for primary stroke prevention.
Objective To determine the prevalence of abnormal cerebral blood flow velocity (CBFV) in children with SCD and describe CBFV in children without SCD.
Methods We conducted a two-component study comprising a retrospective review and a cross-sectional assessment. TCD measurements from 143 children with confirmed SCD aged 2–16 years were reviewed. In a …
Dental Rehabilitation With General Anesthesia And Analysis Of Waiting Time Periods, Hannah Shelton, Bethany Castro, Neena Patel, Robin Onikul, Amy Burleson, Jenna Sparks
Dental Rehabilitation With General Anesthesia And Analysis Of Waiting Time Periods, Hannah Shelton, Bethany Castro, Neena Patel, Robin Onikul, Amy Burleson, Jenna Sparks
Posters
Purpose: The aim of this research project is to understand how long patients are waiting to be seen to have dental rehabilitation completed under general anesthesia at Children’s Mercy Hospital. The data will help determine if additional surgical blocks are needed for dental providers to serve the patient population in a more reasonable time frame. Methods: A retrospective review of all appointments in the CMH dental clinic was conducted for all patients referred for general anesthesia. Data collected included patient wait times, patient age, ASA (American Society of Anesthesiologists) classification, type of appointment in which GA referral was made, and …
Impact Of Intracranial Pressure Monitoring On 30-Day Mortality In Severe Traumatic Brain Injury: A Retrospective Cohort Study In Kenya, George Ongas, Idris Chikophe, Jacqueline Mavuti, David Olunya, Mubashir Qureshi, Beverly Cheserem, Edwin Mogere
Impact Of Intracranial Pressure Monitoring On 30-Day Mortality In Severe Traumatic Brain Injury: A Retrospective Cohort Study In Kenya, George Ongas, Idris Chikophe, Jacqueline Mavuti, David Olunya, Mubashir Qureshi, Beverly Cheserem, Edwin Mogere
General Surgery, East Africa
OBJECTIVE The objective of this study was to evaluate 15-year trends in epidemiology, baseline severity, management, and outcomes of severe traumatic brain injury (sTBI) at a Kenyan tertiary center, and to determine the impact of invasive intracranial pressure (ICP) monitoring on 30-day mortality in a low- and middle-income country (LMIC) context.
METHODS A retrospective quasi-experimental cohort analysis of consecutive sTBI admissions (postresuscitation Glasgow Coma Scale [GCS] score ≤ 8, age ≥ 13 years) from January 1, 2010, to December 31, 2024, was conducted. This time period was divided into two eras: era 1 (2010–2014), premonitoring, and era 2 (2015–2024), routine …
The Intersection Between Adolescent Pregnancy, Mental Health Concerns, Stigma, And Sex Education, Madelon Cox
The Intersection Between Adolescent Pregnancy, Mental Health Concerns, Stigma, And Sex Education, Madelon Cox
Honors Program: Senior Projects (Public)
This thesis discusses research from the past two decades focused on factors contributing to an increased risk of adolescent pregnancy and the lasting impact of that pregnancy. The consequences of being a pregnant adolescent can be compounded by race, gender, socioeconomic class, and access to education. Adolescent pregnancy also carries significant physical and mental health risk for the adolescent and the child. Awareness and various interventions can help pregnant adolescents or those who may be at risk for adolescent pregnancy to support them, prevent isolation, and reduce further negative mental health conditions, such as depression and anxiety.
Pedagogical Strategies In Medical Laboratory Science Student Learning Outcomes: A Comparative Study Of Learner-Centered And Lecture-Based Instruction, Kasey Kuker
Medical Laboratory Science Independent Study Projects
Learner centered teaching (LCT) has gained prominence across the health sciences, yet its specific impact on Medical Laboratory Science (MLS) education remains underexamined. This comparative literature review synthesizes findings from various empirical studies to evaluate how active, learner centered pedagogies - such as flipped classrooms, blended learning, team based learning, simulation, gamification, and structured feedback - perform relative to traditional lecture based instruction. Across diverse MLS and allied health contexts, LCT consistently improved cognitive outcomes including examination performance, laboratory skill proficiency, and long term retention. Equally significant were gains in affective outcomes: heightened self efficacy, motivation, engagement, teamwork, and professional …
A Soft Ending, Atara Schulhof
A Different Perspective, Atara Schulhof
A Different Perspective, Atara Schulhof
Quill & Scope
This was the view as I walked out of the hospital where my grandfather was in the ICU—a familiar medical setting seen from an unfamiliar role. The sunset caught me off guard, with its soft light stretching upward and a quiet sky holding more than I could process. A plane passed in the distance, as if moving life forward while mine felt paused. “A Different Perspective” reflects the way medicine changes when you are not the one in the white coat, but the one walking out into the evening, carrying both loss and light.
Testing The In Vitro Effectiveness Of Protease Inhibitors Against Histomonas Meleagridis, Evy Belle Hafer
Testing The In Vitro Effectiveness Of Protease Inhibitors Against Histomonas Meleagridis, Evy Belle Hafer
Animal Science Undergraduate Honors Theses
Histomonas meleagridis is a protozoal parasite able to exist in a flagellated or amoeboid form that infects gallinaceous birds, particularly turkeys, and causes significant mortality. There is currently no effective treatment for this disease. The purpose of this study was to assess the anti-histomonal activity of commercially available protease inhibitors, leupeptin, bestatin, and antipain, using an established in vitro model. Three protease inhibitors, leupeptin, bestatin, and antipain, were evaluated across five assays. Treatment groups included: 1) non-treated control, 2) leupeptin 100 µM, 3) bestatin hydrochloride 100 µM, and 4) antipain dihydrochloride 100 µM. Histomonads were enumerated using a hemocytometer after …
A Program Evaluation Of A Family-Based Healthy Weight Program For Overweight And Obese Children And Their Families, Ashley Heimbouch, Margaret Platel, Kelly Betts
A Program Evaluation Of A Family-Based Healthy Weight Program For Overweight And Obese Children And Their Families, Ashley Heimbouch, Margaret Platel, Kelly Betts
Doctor of Nursing Practice Projects: College of Nursing
This project’s purpose was to complete a program evaluation of the Building Healthy Families (BHF) program to determine its effect on children and their families’ health outcomes. The specific aims of success were 1) an improved perception of health-related quality of life for children and parents and 2) decreased body mass index (BMI) percentiles for age and sex in children from baseline measurements and scores compared to measurements and scores at 3 months and 6 months of program completion. The project was completed in a community setting on the University of Nebraska Medical Center’s Western Nebraska campus, and the population …
Cost Of Health Systems Strengthening For Small And Sick Newborn Care In Four Sub-Saharan African Countries Implemented With Nest360: Incremental Cost Analyses, Alice Tarus, Meghan Kumar, Rebecca Penzias, Rosemary Kamuyu, James Cross, Mbozu Sipalo, Edith Gicheha, Christine Bohne, George Okello, William Macharia
Cost Of Health Systems Strengthening For Small And Sick Newborn Care In Four Sub-Saharan African Countries Implemented With Nest360: Incremental Cost Analyses, Alice Tarus, Meghan Kumar, Rebecca Penzias, Rosemary Kamuyu, James Cross, Mbozu Sipalo, Edith Gicheha, Christine Bohne, George Okello, William Macharia
Paediatrics and Child Health, East Africa
Background
Newborn survival requires high-quality small and sick newborn care (SSNC). Domestic and donor financing for SSNC is low, yet real-world cost data to inform investment are scarce. We analysed primary financial data for SSNC health system improvements nationally in Malawi and subnationally in Kenya, Nigeria, and Tanzania.Methods
We analysed incremental health system perspective costs using hospital-specific assessments, inpatient data (n=93 942 admissions per year), and government and NEST360 costs. We compared annual hospital-specific costs post-implementation (June, 2022, to June, 2023) and pre-implementation (September, 2019, to March, 2021). We calculated per-hospital and per-baby costs disaggregating by health system building …Creating Supportive Environments For Children To Bloom: A Trauma-Informed Occupational Therapy Approach, Morgan Benson
Creating Supportive Environments For Children To Bloom: A Trauma-Informed Occupational Therapy Approach, Morgan Benson
Occupational Therapy Capstone Presentations
A significant number of children receiving occupational therapy services have histories of adverse childhood experiences (ACEs), including neglect, abuse, frequent changes in caregiving environments, and exposure to chronic stressors. These experiences can strongly affect sensory processing, emotional regulation, behavior, and participation in meaningful daily occupations. These challenges are often made more complex by limited caregiver education, inconsistent access to trauma-informed resources, and differences in therapist confidence when addressing trauma in pediatric practice. Occupational therapy practitioners are well-positioned to support these needs through holistic, occupation-based, and client-centered care that considers sensory, emotional, environmental, and developmental factors. The purpose of this capstone …
Enhancing Child Development In A Daycare Setting Using An Ot Perspective, Autumn F. Glaser
Enhancing Child Development In A Daycare Setting Using An Ot Perspective, Autumn F. Glaser
Occupational Therapy Capstone Presentations
The purpose of this capstone project was to implement a program within a daycare setting using an occupational therapy perspective. The project explored the impact of staff education combined with guided, hands-on activities in supporting child development. Seven developmental areas served as a focus for two weeks each during the capstone experience. Main components of the program included presentations and debrief sessions for staff, hands-on, developmentally supportive activities with the children, handouts for caregivers, and the creation of a resource with activity ideas for daycare staff to utilize after program implementation. Pre and post-test surveys were used to assess the …
Blooming Beginnings: An Occupational Therapy Approach To Helping Families Grow, Grace L. Mcconnell
Blooming Beginnings: An Occupational Therapy Approach To Helping Families Grow, Grace L. Mcconnell
Occupational Therapy Capstone Presentations
The transition to parenthood is accompanied by monumental changes in health, wellness, roles, and routines. These changes impact an individual's ability to participate in their daily activities and particularly for mothers, this experience impacts her entire life. Through this transition, parents must not only participate in their own occupations but also learn how to advocate and care for their child(ren). However, families are provided very limited educational resources to prepare them for this transition. Occupational therapy can bridge the gap in family preparedness by utilizing evidence-based education to address physical, psychological, and social wellbeing. Occupational therapy education can advise parents …
Empowering Children Through Self-Regulation: A Multi-Setting Occupational Therapy Initiative, Aarika Denae De Jong
Empowering Children Through Self-Regulation: A Multi-Setting Occupational Therapy Initiative, Aarika Denae De Jong
Occupational Therapy Capstone Presentations
Self-regulation skills are essential for well-being during childhood and are associated with academic performance and positive psychosocial outcomes. Children with developmental disabilities such as autism spectrum disorder (ASD) often experience sensory differences that impact occupational performance and self-regulation. Rural populations face additional barriers to accessing early childhood opportunities and occupational therapy services. This doctoral capstone project aimed to support the development of self-regulation skills among children in both clinical and community settings. Through partnership with a rural public library, a Sensory Storytime Program was implemented using inclusive design principles to promote regulation skills. Additional resources, including a Sensory Regulation Kit …
Integrating Trauma-Informed Care Into Pediatric Occupational Therapy, Kylie H. Rodig
Integrating Trauma-Informed Care Into Pediatric Occupational Therapy, Kylie H. Rodig
Occupational Therapy Capstone Presentations
This capstone project examined how trauma-informed care (TIC) and Trust-Based Relational Intervention® (TBRI) can be integrated into pediatric occupational therapy to better support children impacted by trauma. The project was guided by the question of how structured trauma-informed strategies, clinical tools, and caregiver education influence therapist understanding and application in practice.
A mixed-methods approach was used, incorporating TIC- and TBRI-informed interventions during pediatric treatment sessions, trauma-informed evaluations, and ongoing reflective practice. Data were gathered through pre- and post-surveys, informal staff feedback, and reflective logs to capture changes in knowledge, confidence, and clinical application over time.
Results showed clear improvements in …
The Impact Of Increased Beef Intake On Cardiometabolic Health In Postmenopausal Women: A 16-Week Randomized Controlled Trial, Leen Samman
Biological Sciences Undergraduate Honors Theses
By 2030, it is projected that the number of post-menopausal women globally will reach 1.2 billion. Moreover, because of increases in life expectancy, women will spend a greater proportion of their later years at elevated risk of chronic disease associated with the hormonal changes of the menopausal transition. Dietary interventions, specifically high-protein diets have shown potential mitigating effects; however, most interventions have focused on total protein intake or protein supplements, not whole foods like lean beef. This randomized controlled trial aimed to assess the effects of daily lean beef consumption as part of a higher protein diet on cardiometabolic markers …
Oxytocin-Mediated Trust Formation In Relationship-Based Sales, Isabella G. Farrington
Oxytocin-Mediated Trust Formation In Relationship-Based Sales, Isabella G. Farrington
Biological Sciences Undergraduate Honors Theses
Trust is a critical driver of success in relationship-based sales, particularly in complex environments such as medical, pharmaceutical, and B2B markets where decisions involve uncertainty, risk, and long-term commitment. Existing research in marketing and psychology primarily explains trust through interpersonal behaviors, communication, and relationship management strategies. However, the biological mechanisms underlying trust formation remain largely underexplored in these contexts.
This thesis examines the role of oxytocin, a neuropeptide associated with social bonding and cooperation, in shaping trust and decision-making in professional sales environments. Drawing on research from neuroscience, neuroeconomics, and relationship marketing, it proposes that oxytocin-mediated processes provide a biological …
Baystate Health Nursing: Together In Excellence Newsletter - May 2026, Brenda Simpson Rn
Baystate Health Nursing: Together In Excellence Newsletter - May 2026, Brenda Simpson Rn
Baystate Health Nursing: Together in Excellence Newsletters
Baystate Health Nursing: Together in Excellence Newsletter - May 2026
Improving Dimensional Stability Of Irreversible Hydrocolloid By Condensation Silicone Incorporation, Jefferson David Melo De Matos, João Pedro Oliveira De Batista, Jozely Francisca Mello Lima, Mário Alexandre Coelho Sinhoreti, Umberto Demoner Ramos, Daher Antonio Queiroz, Daniel Sartorelli Marques De Castro
Improving Dimensional Stability Of Irreversible Hydrocolloid By Condensation Silicone Incorporation, Jefferson David Melo De Matos, João Pedro Oliveira De Batista, Jozely Francisca Mello Lima, Mário Alexandre Coelho Sinhoreti, Umberto Demoner Ramos, Daher Antonio Queiroz, Daniel Sartorelli Marques De Castro
Faculty, Staff and Student Publications
Background: Irreversible hydrocolloid (alginate) is widely used for dental impressions, but its poor dimensional stability over time limits accuracy when delays in pouring occur. Enhancing its stability through material modification, such as incorporating condensation silicone, may improve clinical outcomes.
Materials and methods: Three groups (n = 10) were evaluated: Group I (conventional alginate, Avagel), Group II (extended-pour alginate, Hydrogum 5), and Group III (alginate modified with condensation silicone). Specimens were fabricated using standardized molds and stored under controlled humidity. Dimensional stability was assessed at five time points (immediate, 24, 48, 72, and 120 h) by measuring mass and linear dimensions. …
Interventional Approach To Intermediate-High-Risk Pe: Catheter-Directed Mechanical Thrombectomy, Shreya Agarwal, Kirill Ruban, Ishan Kirti, Karina Ruban, Fadi Saab, Sujata Kambhatla, Pranay Gupta
Interventional Approach To Intermediate-High-Risk Pe: Catheter-Directed Mechanical Thrombectomy, Shreya Agarwal, Kirill Ruban, Ishan Kirti, Karina Ruban, Fadi Saab, Sujata Kambhatla, Pranay Gupta
Conference Presentation Abstracts
Acute pulmonary embolism (PE) is a major cause of cardiovascular morbidity and mortality. The clinical outcomes are largely determined by thrombus burden and its hemodynamic impact on the right ventricle (RV). Over the past decade, catheter-directed mechanical thrombectomy has emerged as a promising alternative for systemic thrombolysis for PE management, particularly in patients at high risk for major bleeding. This approach provides rapid mechanical debulking of thrombus without exposure to thrombolytics and has been associated with significant improvements in RV function and pulmonary artery pressures. We present a case of extensive bilateral PE successfully treated with mechanical thrombectomy, highlighting the …
Bulletin Ninth District Ny May 2026
Bulletin Ninth District Ny May 2026
Bulletin of the Ninth District Dental Association
In the May 2026 issue, the reader will find the following feature articles:
- "ADA Lobby Day 2026"
- "Dentistry for Individuals with Special Needs"
- "ADA Trustee Corner"
- "CE Navigator FAQ"
- "NYSDA Wins in 2025"
- "Peer Review and Quality Assurance: What is it and Why is it an Important Member Benefit?"
Also included are your monthly President's Message, event updates, continuing education opportunities, membership news and classifieds.
Dentistry For Individuals With Special Needs, William J. Maloney
Dentistry For Individuals With Special Needs, William J. Maloney
Bulletin of the Ninth District Dental Association
Dentists have a profound responsibility to champion special needs patients through patience, trust, accessibility, collaboration, and individualized care—recognizing that thoughtful accommodations and compassion are essential to safe treatment, dignity, and lifelong oral health.
This article discusses social-emotional, practical, and clinical considerations for best serving patients with disabilities. A list of tips specifically for improving the experience of dental visits for pediatric patients with developmental disabilities is included.
Operative Versus Non-Operative Management Of Infant Perianal Abscesses: A Pediatric Surgery Research Collaborative Prospective Quality Improvement Study, Leigh Selesner, Chakshu Soni, Romeo C. Ignacio, Rimla Khan, Robert Wright, Alicia Mcintire, Bethany J. Slater, Nathan M. Novotny, Ryan T. Davis, Artem F. Dadamyan
Operative Versus Non-Operative Management Of Infant Perianal Abscesses: A Pediatric Surgery Research Collaborative Prospective Quality Improvement Study, Leigh Selesner, Chakshu Soni, Romeo C. Ignacio, Rimla Khan, Robert Wright, Alicia Mcintire, Bethany J. Slater, Nathan M. Novotny, Ryan T. Davis, Artem F. Dadamyan
Conference Presentation Abstracts
Abstract: Purpose Treatment of infant perianal abscesses (IPA) remains controversial, with ongoing debate between operative and non-operative management. Recurrence is common and prospective data to guide care are lacking. We performed the first multi-institutional prospective quality improvement (QI) study comparing non-operative to operative IPA management. Methods The primary endpoint was time to complete abscess resolution. Secondary endpoints included surgical intervention (incision and drainage ± fistulotomy) and abscess recurrence. Institutions were recruited through a national research collaborative. IRB approval was obtained individually. Between 2022 and 2025, we prospectively enrolled patients < 1 year of age with an abscess ≤2 cm from the anal verge. Patients with predisposing conditions (e.g. inflammatory bowel disease) were excluded. Management was determined by the treating provider, with either upfront surgical intervention (control group) or non-operative care per our QI protocol (protocol group, Figure 1). Data were collected on management prior to surgical evaluation, presentation, subsequent treatment and outcomes. Statistical analyses were performed using STATA, with p < 0.05 considered significant. Endpoints were compared between groups by non-parametric methods, with denominators based on available data. Results Fourteen institutions participated across the U.S., with a total of 288 patients (108 control, 180 protocol) enrolled. Median follow-up was 0.99 (interquartile range 0.23-3.93) and 1 (0.16-4.56) months for control and protocol groups. Abscess resolution occurred in 155 patients during follow-up (36/71 (51%) control, 119/134 (89%) protocol, p < 0.01). Median time to abscess resolution was 1.21 (0.33-4) and 1.13 (0.57-3.83) months for control and protocol groups (p=0.64). Recurrences were frequent in both cohorts (34/93 (37%) control, 62/153 (41%) protocol). Surgical intervention was significantly more common in the control group: incision and drainage were performed in 61/107 (57%) versus 19/166 (11%) and exam under anesthesia with fistulotomy in 31/106 (29%) versus 20/166 (12%) (both p< 0.01). Conclusions Time to abscess resolution was similar between patients treated with upfront surgical intervention and non-operative management according to our QI protocol. Significantly more patients underwent surgical intervention in the control group, without an impact on time to resolution. Our data support initial non-operative management of infant perianal abscesses, emphasizing antibiotics at initial presentation, sitz baths and family reassurance. Abbreviations: IPA - infant perianal abscess; QI - quality improvement; IRB - institutional review board
Fetal Vascular Malperfusion And Other Placental Lesions In Relation To Maternal Sars-Cov-2 Exposure: A Case–Control Study, Irene Mwandoto, Marleen Temmerman, Ingrid Gichere, Patricia Okiro
Fetal Vascular Malperfusion And Other Placental Lesions In Relation To Maternal Sars-Cov-2 Exposure: A Case–Control Study, Irene Mwandoto, Marleen Temmerman, Ingrid Gichere, Patricia Okiro
Pathology, East Africa
Background:
The morphologic characteristics of placentas associated with coronavirus disease-19 (COVID-19) have been described but with varying findings. Studies conducted at the onset of the pandemic reported frequency of Fetal Vascular Malperfusion (FVM), an umbrella term that describes occlusive vasculopathies that affect fetal circulation and their associated sequelae. Morphologic manifestations include thrombosis, avascular villi and vascular stromal karyorrhexis. Associated outcomes include fetal growth restriction, thromboembolic events such as neonatal stroke and fetal demise. Placental lesions associated with a severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infection present a unique picture in histology, especially in the attempt to decipher the …
Breastfeeding Support For Mothers Of Low Birthweight Infants In Hospitals In Rural Western Kenya: An Exploratory Study, Fiona Dickinson, Florence Were, Alloys K’Oloo, Iwaret Otiti, Linda Tindi, Mwanamvua Boga, Mary Kimani, Laura Kiige, Kathy Mellor, Helen Nabwera
Breastfeeding Support For Mothers Of Low Birthweight Infants In Hospitals In Rural Western Kenya: An Exploratory Study, Fiona Dickinson, Florence Were, Alloys K’Oloo, Iwaret Otiti, Linda Tindi, Mwanamvua Boga, Mary Kimani, Laura Kiige, Kathy Mellor, Helen Nabwera
Centre of Excellence in Women and Child Health
Background One in ten newborns in sub-Saharan Africa weigh < 2500 g (i.e. low birthweight [LBW]). Breastfeeding difficulties from birth are common among LBW infants. This study explored the use of trained peer mothers to deliver breastfeeding support to mothers of LBW infants in healthcare facilities in rural Kenya.
Methods Five trained peer mothers provided breastfeeding support to 23 mothers of LBW infants across eight healthcare facilities in Homa Bay County. Qualitative, semi-structured interviews were conducted with 11 mothers, 10 healthcare providers and 5 peer mothers prior to and during the breastfeeding support intervention. Inductive thematic analysis was used.
Results Three key themes were discovered: mothers valued the confidence the peer mothers gave them to breastfeed their LBW infants, peer mothers found that the training and their previous experience caring for LBW infants enabled them to work collaboratively with mothers …
Global Perspectives On Central Nervous System Drug Innovation: Achievements, Barriers, And Priorities For The Next Decade, Hiroyuki Uchida, Gabriella Gobbi, Joseph Zohar, Allan Young, Dan Rujescu, Ming-Chyi Huang, Suresh Sundram, Lukoye Atwoli, Jana Vukovic, Kazutaka Ikeda
Global Perspectives On Central Nervous System Drug Innovation: Achievements, Barriers, And Priorities For The Next Decade, Hiroyuki Uchida, Gabriella Gobbi, Joseph Zohar, Allan Young, Dan Rujescu, Ming-Chyi Huang, Suresh Sundram, Lukoye Atwoli, Jana Vukovic, Kazutaka Ikeda
Internal Medicine, East Africa
Background Over the past decade, neuropsychopharmacology has shifted from stagnation to momentum, with first-in-class mechanisms and biomarker-enabled trials spanning psychiatry and neurology.
Methods We narratively synthesized advances from 2013 to 2026 across central nervous system (CNS) discovery and development, including pivotal trials, regulatory actions, digital/real-world evidence, genetics, artificial intelligence (AI), and implementation/global-access themes that are endorsed by international societies.
Results Therapeutic gains include rapid-acting drugs for treatment-resistant depression (intranasal esketamine); psychedelic-assisted therapy for posttraumatic stress disorder and depression; neuroactive steroid γ-aminobutyric acid-A receptor positive allosteric modulators (brexanolone, zuranolone) for postpartum depression; non-dopaminergic muscarinic agonists (xanomeline–trospium) for schizophrenia; orexin receptor antagonists …
Construction Workers Noise Exposure And Hearing Conservation Program Needs, Quinn Noelle Overlin
Construction Workers Noise Exposure And Hearing Conservation Program Needs, Quinn Noelle Overlin
Doctoral Scholarly Projects & Capstones
Noise exposure among construction workers is a pervasive occupational hazard with serious implications for long-term hearing health and overall well-being. This literature review examines the extent of noise exposures in the construction industry and the long-standing need for implementation of effective hearing conservation programs (HCPs). It synthesizes current evidence on exposure levels, health outcomes, and the effectiveness of existing interventions. Findings reveal that construction workers are routinely exposed to noise levels that exceed occupational safety standards, resulting in a heightened risk of noise-induced hearing loss (NIHL) and associated health consequences. Despite regulatory frameworks and available intervention strategies, substantial gaps persist …