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Articles 3571 - 3600 of 321422

Full-Text Articles in Medicine and Health Sciences

Standardizing Interprofessional Serious Illness Conversations In Inpatient Specialty Palliative Care, Leah Mccann Klug, Catherine Patterson Jun 2026

Standardizing Interprofessional Serious Illness Conversations In Inpatient Specialty Palliative Care, Leah Mccann Klug, Catherine Patterson

All Poster Presentations

No abstract provided.


Thromboembolic Outcomes In Patients Receiving Doacs With Concomitant Antiseizure Medication, Hermela Gebregiogris, Brittanii Prahl, Michael Schirmer, Barbara Branneman, Jack Huber, Lam Vo Jun 2026

Thromboembolic Outcomes In Patients Receiving Doacs With Concomitant Antiseizure Medication, Hermela Gebregiogris, Brittanii Prahl, Michael Schirmer, Barbara Branneman, Jack Huber, Lam Vo

All Poster Presentations

No abstract provided.


Optimizing Cochlear Implant Follow Up: An Analysis Of Mstb 3 Proposed Timeline Changes, Alexandra Parbery-Clark, Dylan Severson, Sachin Gupta, Nadav Brumer, Elizabeth Elkins, Chantel Hazlewood, Jake Hillyer Jun 2026

Optimizing Cochlear Implant Follow Up: An Analysis Of Mstb 3 Proposed Timeline Changes, Alexandra Parbery-Clark, Dylan Severson, Sachin Gupta, Nadav Brumer, Elizabeth Elkins, Chantel Hazlewood, Jake Hillyer

All Poster Presentations

No abstract provided.


Comparative Analysis Of Emergency Department Pain Medications Given For Treatment Of Sickle Cell Pain Crisis, Christo Mitchell, Kristian Campbell, Brittanii Prahl, Jack Huber Jun 2026

Comparative Analysis Of Emergency Department Pain Medications Given For Treatment Of Sickle Cell Pain Crisis, Christo Mitchell, Kristian Campbell, Brittanii Prahl, Jack Huber

All Poster Presentations

No abstract provided.


Aviation Accident Investigation Analysis Methodologies Used By 12 Government Safety Investigation Authorities, Kym Bills, Leesa Costello, Marcus Cattani Jun 2026

Aviation Accident Investigation Analysis Methodologies Used By 12 Government Safety Investigation Authorities, Kym Bills, Leesa Costello, Marcus Cattani

Research outputs 2022 to 2026

Introduction: Leading government Safety Investigation Authorities (SIAs) that investigate major aviation accidents are members of the International Transportation Safety Association (ITSA). Investigation analysis methodology details are rarely included on SIA websites, in final accident reports, shared with peers, or specified by the International Civil Aviation Organization (ICAO). Some ‘New View’ safety researchers assume SIAs don't use systemic methodologies and that accident investigation has little value. Because of the sensitivity of SIA work and need to prioritize safety value from available investigation funding, there has been little academic research on choice and use of investigation analysis methodologies to address these issues …


Impacts Of The Early Collaborative Intervention On Mother-Preterm Infant Interaction At One Month Of Age: Secondary Analysis Of A Randomized Controlled Trial, Charlotte Sahlén Helmer, Ulrika Birberg Thornberg, Thomas Abrahamsson, Evalotte Mörelius Jun 2026

Impacts Of The Early Collaborative Intervention On Mother-Preterm Infant Interaction At One Month Of Age: Secondary Analysis Of A Randomized Controlled Trial, Charlotte Sahlén Helmer, Ulrika Birberg Thornberg, Thomas Abrahamsson, Evalotte Mörelius

Research outputs 2022 to 2026

Background A sensitive, well-functioning maternal interaction is vital for healthy infant development. For moderate to late preterm infants, this is even more important as this group of infants are at increased risk of facing neurodevelopmental disorders. The Early Collaborative Intervention supports parent-preterm infant interaction and includes three sessions, two in the hospital and one after discharge. Objective To investigate the impact of the Early Collaborative Intervention, compared with standard care, on mother-preterm infant interaction at one month corrected age. Design A longitudinal randomized controlled trial, reporting secondary outcomes from the first follow-up. Setting The intervention was conducted at a pediatric …


Exploring The Fidelity Of Resistance Training Interventions In Regional, Rural, And Remote Cancer Care: A Systematic Scoping Review, Christopher W. Rowe, Nicolas H. Hart, Julia Carlino, James Murray Jun 2026

Exploring The Fidelity Of Resistance Training Interventions In Regional, Rural, And Remote Cancer Care: A Systematic Scoping Review, Christopher W. Rowe, Nicolas H. Hart, Julia Carlino, James Murray

Research outputs 2022 to 2026

Resistance-based exercise interventions are an integral part of supportive cancer care, though their high quality and high-fidelity implementation with people with cancer living in non-metropolitan locations is challenging. This systematic scoping review aimed to identify how exercise prescription principles and measures of fidelity are reported in resistance-based exercise interventions delivered to people with cancer living in regional, rural and remote areas. A systematic scoping review was conducted in accordance with the PRISMA-ScR guidelines. Five electronic databases were searched (MEDLINE/PubMed, Embase, CINAHL, SCOPUS and SportDiscus) for peer-reviewed studies published in English, that delivered a resistance-based exercise intervention to adult cancer survivors …


Influence Of Intended Slow And Fast Eccentric Back Squat Velocity On Subsequent Countermovement Jump Performance, Artemis Zarkadoula, Themistoklis Tsatalas, Anthony D. Kay, Anthony J. Blazevich, Christos Kokkotis, Spyridon Plakias, Brett Anthony Baxter, Alex J. Van Enis, Giannis Giakas, Minas A. Mina Jun 2026

Influence Of Intended Slow And Fast Eccentric Back Squat Velocity On Subsequent Countermovement Jump Performance, Artemis Zarkadoula, Themistoklis Tsatalas, Anthony D. Kay, Anthony J. Blazevich, Christos Kokkotis, Spyridon Plakias, Brett Anthony Baxter, Alex J. Van Enis, Giannis Giakas, Minas A. Mina

Research outputs 2022 to 2026

Background: The back squat is a key strength and conditioning exercise used to develop lower-limb strength and power, yet little is known about how movement velocity influences its acute performance-enhancing effects, such as improvements in countermovement jump height and power. The present study examined the acute effects of slow (vslow) versus fast (vfast) eccentric-phase velocity during back squats performed withmaximal concentric velocity on subsequent countermovement jump (CMJ) performance, using a randomized, crossover design. Methods: Fourteen male subjects (age = 22.9 ± 1.9 years; height = 1.8 ± 0.1 m; mass = 76.4 ± 8.3 kg) visited the laboratory on two …


Maternal Prenatal Anxiety And Risk Of Preterm Birth And Low Birthweight: Evidence From A Cumulative Meta-Analysis With Stability Thresholds, Bereket Duko, Desta, Biniyam Sahiledengle, Yohannes Tekalegn Efa, Tenaw Tiruye, Lisa Whitehead, Gavin Pereira, Amanuel Tesfay Gebremedhin Jun 2026

Maternal Prenatal Anxiety And Risk Of Preterm Birth And Low Birthweight: Evidence From A Cumulative Meta-Analysis With Stability Thresholds, Bereket Duko, Desta, Biniyam Sahiledengle, Yohannes Tekalegn Efa, Tenaw Tiruye, Lisa Whitehead, Gavin Pereira, Amanuel Tesfay Gebremedhin

Research outputs 2022 to 2026

Background: We conducted cumulative meta-analyses to quantify the degree to which maternal prenatal anxiety impacts preterm birth (PTB) and low birthweight (LBW), and to identify when findings reached stability, enabling confident recommendations for early interventions. Methods: Following PRISMA guidelines, we systematically searched PubMed/MEDLINE, PsycINFO, Scopus, EMBASE, CINAHL (EBSCO), ProQuest, and the Cochrane Library from database inception to May 7, 2025. The methodological quality of included studies was assessed using the Newcastle–Ottawa Scale. Inverse variance weighted random-effects cumulative meta-analysis was performed to pool adjusted odds ratios (AORs) with sequential inclusion of newly published studies. Stability thresholds were computed to assess sufficiency …


Shape-Based Profiling Of Cortical Bone Mineral Density In Growing Children: A Proof-Of-Concept Pqct Study, Anna Maria Markarian, R. Taaffe, Daniel Galvão, Jodie Cochrane Wilkie, Carolyn J. Peddle-Mcintyre, Daniel J. Schiferl, Robert U. Newton Jun 2026

Shape-Based Profiling Of Cortical Bone Mineral Density In Growing Children: A Proof-Of-Concept Pqct Study, Anna Maria Markarian, R. Taaffe, Daniel Galvão, Jodie Cochrane Wilkie, Carolyn J. Peddle-Mcintyre, Daniel J. Schiferl, Robert U. Newton

Research outputs 2022 to 2026

Background: Understanding how bones adapt during growth is essential for promoting lifelong skeletal health. Peripheral quantitative computed tomography (pQCT) is a widely used imaging technique for assessing volumetric bone mineral density (vBMD) in pediatric populations; however, conventional methods may obscure subtle cortical adaptations. The primary aim of this study was to evaluate the feasibility of shape-based cortical vBMD profiling, with an exploratory objective of assessing its sensitivity to inter-individual variation in lean mass index (LMI). Methods: Eighteen children (6–12 years) underwent pQCT scanning at the 38% and 66% tibial sites (distal and proximal diaphysis). Cortical vBMD was quantified across three …


Ig–Microbiota Binding Patterns In Mothers And Infants: A Scoping Review, Alicia Tan Yi Jia, Christopher S. Peacock, Danielle E. Dye, Claus T. Christophersen Jun 2026

Ig–Microbiota Binding Patterns In Mothers And Infants: A Scoping Review, Alicia Tan Yi Jia, Christopher S. Peacock, Danielle E. Dye, Claus T. Christophersen

Research outputs 2022 to 2026

Studies characterising the immunoglobulin (Ig)-bound microbiota apply varying methodologies, making comparisons difficult. This scoping review synthesised evidence on Ig–microbiota binding patterns in maternal and infant contexts, identified recurrent Ig-bound and -unbound bacteria across studies, and highlighted knowledge gaps for further study. Nine articles investigating Ig–microbiota binding patterns in stool or breastmilk samples in mothers or infants were included. Ig–microbiota associations were influenced by sample type, Ig-subclass, genetics, and diet. The most important antibody was IgA, with partial functional redundancy with IgM, while IgG appeared more selective for pathobionts. Ig-bound taxa in early life included important commensals and pathobionts, with high …


Dietary Vitamin K Intakes, Chronic Obstructive Pulmonary Disease, Adult Asthma, And Lung Function: A Prospective Cohort Study In The Uk Biobank, Chengfeng Li, Pratik Pokharel, Marc Sim, Kevin Murray, Catherine P. Bondonno, Benjamin H. Parmenter, Liezhou Zhong, Montana Dupuy, Howraman Meteran, Jette Jakobsen, Allan Linneberg, Tilman Kühn, Aedín Cassidy, Nicola P. Bondonno Jun 2026

Dietary Vitamin K Intakes, Chronic Obstructive Pulmonary Disease, Adult Asthma, And Lung Function: A Prospective Cohort Study In The Uk Biobank, Chengfeng Li, Pratik Pokharel, Marc Sim, Kevin Murray, Catherine P. Bondonno, Benjamin H. Parmenter, Liezhou Zhong, Montana Dupuy, Howraman Meteran, Jette Jakobsen, Allan Linneberg, Tilman Kühn, Aedín Cassidy, Nicola P. Bondonno

Research outputs 2022 to 2026

Background: Vitamin K–dependent proteins are important for maintaining lung structure and function, yet few studies have examined dietary vitamin K intake in relation to chronic respiratory disease. Objectives: This study aimed to investigate the associations between dietary intakes of vitamin K1 and vitamin K2 and the incidence of chronic obstructive pulmonary disease (COPD), asthma, and lung function. Methods: We analyzed data from 179,062 UK Biobank participants without COPD or asthma. Associations between dietary vitamin K1 and K2 intakes, estimated using the Oxford WebQ 24-h recall, and incident COPD and asthma, identified through hospital, death, and primary care records, were examined …


Multi-Sensory Information And Simulator Immersion: Impact On Decision-Making Performance, Presence, And Cognitive Load, Zachariah G. Hoyne, Khaya Morris-Binelli, Sean Müller, Benjamin Piggott, Paola Chivers, Evan Dekker Jun 2026

Multi-Sensory Information And Simulator Immersion: Impact On Decision-Making Performance, Presence, And Cognitive Load, Zachariah G. Hoyne, Khaya Morris-Binelli, Sean Müller, Benjamin Piggott, Paola Chivers, Evan Dekker

Research outputs 2022 to 2026

Immersive technologies such as 360-degree video virtual reality (360VR) provide unique opportunities to simulate representative environments to investigate decision-making in a safe and cost-effective manner. Inclusion of multi-sensory visual, contextual, and auditory information is important to enhance simulator psychological fidelity. Yet, the influence of increased sensory information on decision-making, presence, and cognitive load in 360VR compared to less immersive two-dimensional video simulators is unknown. This study investigated multi-sensory information, presence, and cognitive load across immersion conditions (360VR and two-dimensional video) in an exemplar sport-specific decision-making task. Fifteen higher-skilled and 15 lesser-skilled Australian Rules Football players completed a decision-making task which …


Occupational Therapy Intervention For Children With Developmental Coordination Disorder: A Survey Of Occupational Therapists In Australia, Jacqui Hunt, Jill G. Zwicker, Annette Raynor, Erin Godecke Jun 2026

Occupational Therapy Intervention For Children With Developmental Coordination Disorder: A Survey Of Occupational Therapists In Australia, Jacqui Hunt, Jill G. Zwicker, Annette Raynor, Erin Godecke

Research outputs 2022 to 2026

Introduction: Developmental coordination disorder (DCD), a common neurodevelopmental condition, is associated with persistent motor and psychosocial difficulties impacting participation and quality of life. International guidelines recommend activity-/participation-focused, task-specific interventions; however, little is known about how Australian occupational therapists translate these recommendations into clinical practice. This study aimed to describe current Australian occupational therapy intervention for children with (or suspected to have) DCD and identify factors that shape occupational therapists' intervention choices. Methods: A cross-sectional online survey was distributed to Australian occupational therapists via professional organisations/social media September–October 2020. Eligible participants were registered occupational therapists with ≥15% children in their caseload. …


The Interplay Between Osteosarcopenia And Intrinsic Capacity: Insights And Associations With All-Cause Mortality In The Toledo Study For Healthy Aging, Ivan Baltasar-Fernandez, Pedro L. Valenzuela, Irene Rodríguez-Gómez, Fabio Quiñonez-Bareiro, Luis M. Alegre, Konstantinos Prokopidis, Leocadio Rodriguez-Mañas, Ignacio Ara, Oscar Rosas-Carrasco, Lana J. Williams, Robinson Ramirez-Vélez, Julie A. Pasco, Guy Hajj-Boutros, Raman Agnihotram, Marc Sim, Wayne Lok Ok Choo, Mahdi Imani, Ana M. Ayala-Copete, Julia Chabot, Miguel G. Borda, Nailton J. Neto, Claire Godard-Sebillotte, Howard Bergman, Anna Andrianova, Hidenori Arai, Pierrette Gaudreau Jun 2026

The Interplay Between Osteosarcopenia And Intrinsic Capacity: Insights And Associations With All-Cause Mortality In The Toledo Study For Healthy Aging, Ivan Baltasar-Fernandez, Pedro L. Valenzuela, Irene Rodríguez-Gómez, Fabio Quiñonez-Bareiro, Luis M. Alegre, Konstantinos Prokopidis, Leocadio Rodriguez-Mañas, Ignacio Ara, Oscar Rosas-Carrasco, Lana J. Williams, Robinson Ramirez-Vélez, Julie A. Pasco, Guy Hajj-Boutros, Raman Agnihotram, Marc Sim, Wayne Lok Ok Choo, Mahdi Imani, Ana M. Ayala-Copete, Julia Chabot, Miguel G. Borda, Nailton J. Neto, Claire Godard-Sebillotte, Howard Bergman, Anna Andrianova, Hidenori Arai, Pierrette Gaudreau

Research outputs 2022 to 2026

Background: Osteosarcopenia—the coexistence of osteopenia/osteoporosis and sarcopenia—is associated with numerous adverse health outcomes, but its association with intrinsic capacity (IC) remains unknown. We aimed to explore the associations of osteosarcopenia with IC and all-cause mortality in older adults. Methods: We conducted a cross-sectional analysis of IC and a prospective analysis of all-cause mortality in 1142 participants from the Toledo Study for Healthy Aging (75.1 ± 6.0 years, 53.1% women). Participants were classified as having no musculoskeletal disorders, osteopenia/osteoporosis, sarcopenia, or osteosarcopenia (DXA- and EWGSOP2-based criteria). IC was operationalized as a composite score integrating locomotion, cognition, psychological, vitality, and sensory domains. …


Marshall University 2026 College Of Health Professions Student Research Day, Cohp Research Committee Jun 2026

Marshall University 2026 College Of Health Professions Student Research Day, Cohp Research Committee

Appalachian Student Healthcare Research Review

Marshall University

2026 College of Health Professions Student Research Day

April 16, 2026

Student Oral Presentations

1. Validity of Using Smartphone Cameras and Pose Estimation Algorithms for Quantitative Analysis of Human Dynamic Movements

Flanders B, Wolfe T, Saines J, Liang H: School of Physical Therapy

2. Effects of Creatine Supplementation on Anaerobic Capacity and Body Composition in Novice Rock Climbers

George LG, Jones BJ: School of Health and Movement Sciences

3. Relationship Between Musculoskeletal Injuries and Mental Health

Rice C, Konz S: School of Health and Movement Sciences

Student Poster Presentations

4. Effects of Bright Light Therapy on Depression

Adams, …


Development And Validation Of The Lifetime Sense Of Safety Scale In Kenyan Adults, Karen Blackmon, Anne Nyambura, Anne Gitere, Levi Muyela, Catherine Onyancha, Kendi Muchungi, Catherine Ajalo, Litha Musili, Rachel Maina, Edna Bosire, Lukoye Atwoli, Zul Merali, Chinedu Momoh Jun 2026

Development And Validation Of The Lifetime Sense Of Safety Scale In Kenyan Adults, Karen Blackmon, Anne Nyambura, Anne Gitere, Levi Muyela, Catherine Onyancha, Kendi Muchungi, Catherine Ajalo, Litha Musili, Rachel Maina, Edna Bosire, Lukoye Atwoli, Zul Merali, Chinedu Momoh

Brain and Mind Institute

Background. Safety supports psychological wellbeing and potentially shapes brain aging yet existing scales overlook cumulative lifespan safety experiences.

Methods. To address this gap, we developed and validated the Lifetime Sense of Safety (LSS) scale in Kenyan adults. The LSS uses visual analog scaling with a red-to-green color gradient to retrospectively rate felt safety across life stages and settings. We evaluated scale psychometrics and associations with social determinants of health and indicators of brain health.

Results. The LSS shows adequate internal consistency and test-retest reliability, with two distinct but correlated factors representing childhood and adulthood safety. Women and …


Contextual Variability In Under-Diagnosed Cardiometabolic Disease And Cognitive Vulnerability Among Populations At High Risk For Alzheimer's Disease And Related Dementias, Nwanyieze Jiakponnah, Joseph Curran, Tamlyn Watermeyer, Jasmit Shah, Litha Musili, Stanely Onyango, Benard Aliwa, Zul Merali, Karen Blackmon, Chinedu Momoh Jun 2026

Contextual Variability In Under-Diagnosed Cardiometabolic Disease And Cognitive Vulnerability Among Populations At High Risk For Alzheimer's Disease And Related Dementias, Nwanyieze Jiakponnah, Joseph Curran, Tamlyn Watermeyer, Jasmit Shah, Litha Musili, Stanely Onyango, Benard Aliwa, Zul Merali, Karen Blackmon, Chinedu Momoh

Brain and Mind Institute

Underdiagnosis of cardiometabolic risk factors (CMRFs) may represent an unrecognised biological pathway contributing to dementia risk; yet remains poorly characterised in African and African diaspora populations. We quantified the prevalence and determinants of underdiagnosed hypertension and abnormal glycaemia across four cohorts comprising up to 7000 adults aged ≥40 years from Nigeria, Kenya, and The United States: Indianapolis, and North Texas. Underdiagnosis was defined as absence of self-reported diagnosis despite elevated systolic blood pressure ( ≥130 mmHg) or fasting blood glucose ( ≥100 mg/dL). Cohort-stratified analyses examined demographic, socioeconomic, cognitive, Alzheimer’s genetic, and blood-based biomarker correlates. Underdiagnosis was pervasive in African …


Breaking Barriers: Harnessing Collaboration Between Individuals With Disabilities And Emergency Management In New Jersey, Daniel Wrinn Jun 2026

Breaking Barriers: Harnessing Collaboration Between Individuals With Disabilities And Emergency Management In New Jersey, Daniel Wrinn

Master of Science in Emergency & Disaster Management Capstones

No abstract provided.


Comparable Endogenous Immune Reconstitution, Car-T Expansion, And Cytokine Profiles With Bendamustine Versus Fludarabine/Cyclophosphamide Lymphodepletion, Matthew Schwede Jun 2026

Comparable Endogenous Immune Reconstitution, Car-T Expansion, And Cytokine Profiles With Bendamustine Versus Fludarabine/Cyclophosphamide Lymphodepletion, Matthew Schwede

All Podium Presentations

No abstract provided.


Silent Bones, Visible Changes: Increasing Osteoporosis Screening At Swedish Fmr, Alissa Kummer, Devin Beecher, Tara Ahmadi, Amanda Maxwell Jun 2026

Silent Bones, Visible Changes: Increasing Osteoporosis Screening At Swedish Fmr, Alissa Kummer, Devin Beecher, Tara Ahmadi, Amanda Maxwell

All Podium Presentations

No abstract provided.


Quality Improvement: Referral Algorithm For Team-Based Care Of Blood Pressure Control, Hai-Yen Tang, Elise Gibson Jun 2026

Quality Improvement: Referral Algorithm For Team-Based Care Of Blood Pressure Control, Hai-Yen Tang, Elise Gibson

All Podium Presentations

No abstract provided.


Beyond Ce Credit: A Retrospective Analysis Of Cme And Cpe Impact In A Health System, Diem Pham, Michelle Eng, Brandon Wu Jun 2026

Beyond Ce Credit: A Retrospective Analysis Of Cme And Cpe Impact In A Health System, Diem Pham, Michelle Eng, Brandon Wu

All Podium Presentations

No abstract provided.


Nurses' Perspectives On Caring For Critically Ill Children During A Measles Outbreak: A Case Report, Nicole Roehrig Jun 2026

Nurses' Perspectives On Caring For Critically Ill Children During A Measles Outbreak: A Case Report, Nicole Roehrig

All Podium Presentations

No abstract provided.


Impact Of Gum Chewing On Postoperative Ileus Following Open Heart Surgery At Swedish Cherry Hill, Jacinta Smith Jun 2026

Impact Of Gum Chewing On Postoperative Ileus Following Open Heart Surgery At Swedish Cherry Hill, Jacinta Smith

All Podium Presentations

No abstract provided.


Design For Belonging: Environmental Factors Shaping Safety, Trust, And Engagement, Lauren Cole, Rebecca Hawkins Jun 2026

Design For Belonging: Environmental Factors Shaping Safety, Trust, And Engagement, Lauren Cole, Rebecca Hawkins

All Podium Presentations

No abstract provided.


Innovating Cauti Prevention: The Cauti Café And Multidisciplinary Catheter Stewardship At The Bedside, Erik Enquist, Jennifer Neal, Naz Akhavan, Harnishad Binner Jun 2026

Innovating Cauti Prevention: The Cauti Café And Multidisciplinary Catheter Stewardship At The Bedside, Erik Enquist, Jennifer Neal, Naz Akhavan, Harnishad Binner

All Podium Presentations

No abstract provided.


June 2026, Swosu Rural Health Center Jun 2026

June 2026, Swosu Rural Health Center

RURAL ROCKS

Rural Rocks

Second Generation Antipsychotics in the Treatment of Depression

Dr. Debra L. Stevens, Pharm.D., BCPP 

Major depressive disorder (MDD), also known as depression, affects 1 in 5 individuals in their lifetime.1 Worldwide approximately 246 to 286 million individuals are afflicted with MDD.2 MDD may cause significant morbidity and disability. The World Health Organization estimates that MDD will be one of the leading causes of disease burden by 2030.2

A significant number of patients diagnosed with MDD do not respond adequately despite appropriate treatment with antidepressants.2 Treatment resistance may occur in up to one-third of patients …


An Obligatory Role For Agrp Neurons In Maintaining Body Temperature During Time-Restricted Feeding, Cunjin Su, Jing Cai, Yuanzhong Xu, Benjamin R Arenkiel, Qingchun Tong Jun 2026

An Obligatory Role For Agrp Neurons In Maintaining Body Temperature During Time-Restricted Feeding, Cunjin Su, Jing Cai, Yuanzhong Xu, Benjamin R Arenkiel, Qingchun Tong

The Brown Foundation: Institute of Molecular Medicine

Homeotherms maintain a steady body temperature through thermoregulation, a process critical for survival during fasting, in which the brain has to defend energy-costly body temperature while reducing energy expenditure to conserve energy reserve; however, the neural basis for defending body temperature remains unclear. Here, we demonstrated that AgRP neuron lesion led to lethality during time-restricted feeding on chow but not on HFD, and caused no obvious impact on HFD-induced obesity or obesity-reducing responses to glucagon-like peptide-1 receptor agonism. The lesion disrupted adaptive feeding behaviors during time-restricted feeding and reduced motivational feeding on chow. Notably, the lethality was caused by hypothermia …


Understanding And Enhancing Suicide Prevention Strategies In The Military: The Roles Of Culture, Leadership, And Command Climate, Kelly Johanna Pires Jun 2026

Understanding And Enhancing Suicide Prevention Strategies In The Military: The Roles Of Culture, Leadership, And Command Climate, Kelly Johanna Pires

Dissertations

Military service members are shaped and molded to fit a military culture that emphasizes mission readiness and continuous preparedness. Countless hours are spent training for various situations that can arise. Many trainings are geared toward worst-case scenarios that can cause an increase in stressors and traumatic events. They are expected to demonstrate resilience and overcome adversity to remain mission-ready. This expectation to be mission-ready creates the space for mental health difficulties as well as stigma and avoidance of help-seeking behaviors. In many cases, the desire to stay mission-ready creates a barrier for conversations around mental health. The military emphasizes qualities …