Medicine and Health Sciences Commons^™

Trends In Health-Based Drinking Water Violations For Coliform Bacteria In The United States, Amber Lyon-Colbert, Kshipra Sharma

Public Health Faculty Publications

This research seeks to determine whether health-based drinking water violations for total coliforms have increased since the Revised Total Coliform Bacteria Rule established in 2013 and fully implemented in 2016 by the Environmental Protection Agency under the Safe Drinking Water Act; as well as determine the geographic regions, states and territories in the United States with the highest number of health-based Total Coliform Rule and Revised Total Coliform Rule violations. We obtained data for drinking water violations involving total coliform bacteria from the Safe Drinking Water Information System for 2000-2019 and trend analysis was completed by state, region, water source, …

Examining Rural Population Characteristics And Access To Care In 2022: A Study Of Health Professional Shortage Areas (Hpsas) And Medically Underserved Areas (Muas), Craig Holden, Shena Popat, Rachel Van Vleet, Shalanda Henderson, Carina Hoyer, Alana Knudson

ETSU/NORC Rural Health Research Center Policy Briefs

No abstract provided.

An Examination Of All-Payer Inpatient Rural Hospital Bypass, Craig D. Holden, Shena Popat, Alana Knudson, Marilyn G. Klug

ETSU/NORC Rural Health Research Center Policy Briefs

No abstract provided.

The Social And Biological Frontiers Of Polio: Comparing Global Eradication Strategies, Srisai A. Turangi

Honors Program: Senior Projects (Public)

This paper provides a comparative analysis of the divergent global strategies for poliomyelitis (polio) eradication, examining the historical and structural contexts of developed nations – the United States and United Kingdom – alongside the enduring challenges in endemic regions such as Nigeria and Pakistan. Biomedical innovations like the Inactivated Polio Vaccine (IPV) and Oral Polio Vaccine (OPV) have helped bring the world to a state of almost complete global eradication, but progress is still uneven due to variations in funding, healthcare infrastructure, and the legacy of colonialism. Studies reveal how a framework where global health inequalities remained, allowed for resource-rich …

Effect Of Dental Treatments On Reduction Of Preterm Birth: A Systematic Review And Meta-Analysis, Camille Thomas, Shakil Ahmed, Vincenzo Berghella, Romina Brignardello-Petersen, Mohamed El-Rabbany, Catherine Devion, Stefania Ronzoni

Department of Obstetrics and Gynecology Faculty Papers

OBJECTIVE: Periodontal disease is associated with increased risk of preterm birth. Effective management during pregnancy may reduce preterm birth, though clinical trial evidence has been inconsistent. This study aimed to assess whether treating dental disease during pregnancy reduces preterm birth.

DATA SOURCES: A systematic search was performed of EMBASE, MEDLINE, PubMed, Cochrane Library, and trial registries up to December 2023 and re-run in January 2025.

STUDY ELIGIBILITY CRITERIA: Randomized controlled trials (RCTs) enrolling pregnant persons with any dental disease randomized to receive dental treatment vs no treatment were included. No language restriction was applied.

STUDY APPRAISAL AND SYNTHESIS METHODS: Data …

Exposure To Suaahara Ii Interventions And Knowledge Of Maternal And Child Nutrition And Health Among Mothers, Grandmothers, And Male Household Heads: An Association Study In Nepal, Shalini Suresh, Edward A. Frongillo Jr. Ph.D., Deependra K. Thapa, Ramesh P. Adhikari, Subir K. Kole, Femila Sapkota, Manisha Laxmi Shrestha, Kristine Garn, Pooja Rana Pandey, Indra Kshetri, Dipak Sharma, Kenda Cunningham

Faculty Publications

Suaahara was a USAID-funded multi-sectoral integrated nutrition program that aimed to improve the nutritional status of children under the age of five and their mothers in Nepal. The program included multiple interventions targeted to mothers and children, as well as other caregivers. Caregiver knowledge of optimal nutrition and health practices among household members is an important driver of healthy child and maternal nutrition behaviors. This study investigates the associations between exposure to Suaahara interventions and knowledge of maternal and child nutrition and health practices among mothers (n =, grandmothers (n =, and male household heads (n =. Linear and logistic …

Apoe And Plasma Ad Biomarkers: The Role Of Genetic Ancestry In Hispanics/Latinos, Caitlin Cheung, Natasha Z Anita, Paola Filigrana, Myriam Fornage, Kevin A Gonzalez, Linda C Gallo, Carmen R Isasi, Robert C Kaplan, Xihao Li, Freddie Márquez, Humberto Parada, Krista M Perreira, Alberto R Ramos, Tatjana Rundek, Wassim Tarraf, Fernando D Testai, Charles Decarli, Hector M González, Tamar Sofer

Faculty, Staff and Student Publications

Background: Apolipoprotein E (APOE) alleles are well-established genetic risk factors for Alzheimer's disease (AD), but their effects on AD biomarkers (amyloid beta [Aβ]42/40, phosphorylated tau [p-tau]181, neurofilament light chain [NfL], and glial fibrillary acidic protein [GFAP]) may vary across populations due to ancestry-, age-, and sex-related differences. We hypothesized that these effects vary across Hispanic/Latino background groups with distinct ancestral admixture.

Methods: We analyzed ε2 and ε4 allele associations with AD biomarkers using survey-weighted linear regression models, adjusting for demographic covariates. Secondary analyses examined genetic analysis group- and ancestry-specific effects.

Results: ε4 was associated with lower Aβ42/40 and higher p-tau181and …

A Hemodynamic Cascade: Tumor Embolism And Post-Bypass Systolic Anterior Motion During Nephrectomy, Anika Pruthi, Christopher Mcloughlin, Robert Thomas, Keyur Trivedi

Cooper Medical School of Rowan University Departmental Research

Introduction: Renal cell carcinoma (RCC) commonly invades the renal vein, and in advanced cases, the inferior vena cava (IVC). Standard management of localized RCC with venous thrombus is surgical resection, often requiring radical nephrectomy ± tumor thrombectomy. We present a unique case in which sequential intraoperative tumor embolization and post-cardiopulmonary bypass systolic anterior motion (CPB SAM) created a rare, complex hemodynamic cascade, highlighting challenges in the perioperative management of advanced RCC.

Case Description: A 71-year-old female with a history of hypertension was diagnosed with a large left renal mass with tumor thrombus extending into the left renal vein and IVC, …

Application Of A Natural Language Processing Algorithm To Early Asthma Ascertainment For Adults In The Era Of Electronic Health Records, Chung-Il Wi, Thanai Pongdee, Hee Yun Seol, Sunghwan Sohn, Elham Sagheb, Bhavani Singh Agnikula Kshatriya, Shauna M Overgaard, Deepak K Sharma, Sungrim Moon, Elizabeth A Krusemark, Dave Watson, Sergio E Chiarella, Miguel A Park, Jason D Greenwood, Randy M Foss, Zhandong Liu, Meera Gupta, Carla M Davis, Wade Schulz, Hongfang Liu, Young J Juhn

Faculty, Staff and Students Publications

Background: The natural language processing (NLP) algorithm for predetermined asthma criteria (NLP-PAC) was successfully developed and validated for automatically ascertaining pediatric asthma from electronic health record (EHRs) systems. A scalable, efficient, and automated tool for ascertaining adult asthma status from EHRs remains nonexistent.

Objective: We validated NLP-PAC enabling ascertainment and early identification of adult asthma status in their EHRs.

Methods: We applied the validated NLP-PAC to EHRs of a convenient sample (adult cohorts who participated in our previous population-based studies) in which a reference standard (ie, asthma status defined by manual chart review) is available. The performance of NLP-PAC was …

Adenovirus Disease Following Pediatric Liver Transplantation: 10-Year Experience From A Large Pediatric Transplant Program, Anna M Banc-Husu, Sara Hassan, N Thao N Galvan, Elizabeth A Moulton, Jeremy M Schraw, Kathleen Hosek, Dana Cerminara, Flor M Munoz, Krupa Mysore

Faculty, Staff and Students Publications

Background: Human adenovirus in immunocompromised patients can be life-threatening. We describe the prevalence, clinical presentation, and treatment of adenovirus after pediatric liver transplantation at a large transplant center.

Methods: We performed a retrospective cohort study of adenovirus infection in children from 2013 to 2022. We compared incidence, clinical characteristics, and outcomes of post-transplant children by adenovirus treatment status.

Results: Adenovirus disease developed in 26% (84/320) children after liver transplant. Median age at liver transplant was 17.5 months, 48% were female; 50% had biliary atresia. Fever (53%), gastrointestinal symptoms (48%), and hepatitis (41%) were the most common clinical presentations at diagnosis. …

Sepsis At Children's Mercy: A Descriptive Study, Katlyn Mayer, Leslie Hueschen, Grace E. Arends Md, Ashley Sherman

Presentations

No abstract provided.

Substance Use Stigma: Examining The Role Of Social Work Education., Eboni Burton

Doctor of Social Work Capstone Projects

This study explored the extent of substance use related stigma among social work students and professionals (i.e., BSW, MSW, PHD and DSW) and its relationship to specialized education/training in substance use and professional practice with people who use drugs (PWUD)/live with a substance use disorder (PWSUD). Stigma was measured using the Opening Minds Provider Attitudes Toward Opioid Use Scale and the Medical Condition Regard Scale. The final sample size was 263. Results indicate that current enrollment in a social work program, post degree or non-curriculum related substance use related training, and personal and professional experience with substance use specifically, mitigate …

Emergency Department Boarding For Psychiatric Care: The Effect Of Pointclickcare Integration., Chris Rowan

Doctor of Social Work Capstone Projects

Emergency Department Boarding for Psychiatric Care: The Effect of PointClickCare Integration

Abstract

For many individuals in psychiatric crisis, the emergency department has become the first place to seek help, highlighting gaps in how behavioral health care is accessed and coordinated. In Massachusetts, PointClickCare's Behavioral Health Treatment and Referral Platform (BH TRP) was implemented to centralize and streamline referrals between emergency departments and inpatient psychiatric facilities. This capstone evaluates whether implementation of the BH TRP was associated with changes in psychiatric boarding time at a community hospital emergency department. Using a mixed-methods program evaluation design, this study analyzed de-identified electronic medical …

The Unexplored Relationship Between Adverse Childhood Experiences, Burnout, And Resiliency Among Hospital Staff., Elizabeth Davis

Doctor of Social Work Capstone Projects

This study addresses the critical issue of staff turnover at Baptist Health Floyd, where rates exceed national hospital averages. While prior research connects burnout to workplace stressors, less is known about the role of adverse childhood experiences (ACEs) and resilience among hospital staff. Understanding these relationships is essential for improving workforce stability and patient care outcomes. A cross-sectional survey design was used, with convenience sampling of hospital employees and providers (n=207). Data were collected via a Qualtrics survey using validated instruments: the Maslach Burnout Inventory (Maslach et al., 2016), the ACE questionnaire (Felitti et al., 1998), and the Brief Resilience …

Prospective Validation Of Selective Serotonin Reuptake Inhibitor Pharmacokinetic Models For Precision Dosing In Children And Adolescents, Ethan A. Poweleit, Whitney Sparks Ms, Catherine Koertje, Addison Pritchett Ms, Gail Robertson, Lindsey Malloy-Walton, Stephani Stancil, Jeffrey R. Strawn, Alexa L. Pagano, Kathryn Kyler, Jonathan B. Wagner, Brandon Retke, Paul C. Toren, J Steven Leeder Pharmd, Phd, Laura B. Ramsey

Posters

Background: Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed to children and adolescents with anxiety and depression. However, their clinical use is complicated by marked interindividual variability in exposure, which contributes to differences in treatment response and side effects. Further, SSRIs are commonly dosed using a trial-and-error approach. Model-informed precision dosing could improve treatment outcomes, yet existing SSRI population pharmacokinetic (PK) models have not been prospectively validated and may not generalize to pediatric patients. This study aims to evaluate how accurately these models predict exposure for three SSRIs—escitalopram (ESC), sertraline (SRT), and fluoxetine (FLX)—and refine them to develop tools for …

Comparison Of Agar-Based Methodologies To Broth Disc Elution For The Detection Of Aztreonam Susceptibility In The Presence Of Ceftazidime-Avibactam, Teslin Sandstrom, Andra Banete, Alice Kanyua, Kevin Davis, Susan Poutanen

Pathology, East Africa

The combination of aztreonam and ceftazidime-avibactam is a proven treatment option for infections caused by metallo-beta-lactamase (MBL)-expressing gram-negative organisms. Restoration of aztreonam susceptibility in the presence of ceftazidime-avibactam can be determined using the Clinical and Laboratory Standards Institute (CLSI)’s broth disc elution (BDE) method; however, the high manual workload and significant material footprint of this assay make it difficult to implement in a high-throughput clinical microbiology lab. This study evaluates two agar-based methods for the detection of susceptibility to the combination of aztreonam and ceftazidime-avibactam, using BDE as the comparator methodology. Resistant Enterobacterales, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter spp. …

Low-Dose Aspirin For Preventing Intrauterine Growth Restriction And Pre-Eclampsia In Sickle Cell Pregnancy, Lydia Pecker, Sophie Lanzkron

Cardeza Foundation for Hematologic Research

No abstract provided.

Trauma: Blunt Solid Organ Injury, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.

Dr. Deb Peters: Opening Doors As The Ada’S New Speaker, Debra Peters, Christopher J. Smiley

The Journal of the Michigan Dental Association

This interview profiles Dr. Deb Peters, the first female speaker of the ADA House of Delegates. Dr. Peters shares her vision for making the ADA more accessible, transparent, and responsive to its members. She discusses her leadership philosophy, emphasizing listening and mentorship, and explains how effective governance can lead to significant real-world impacts, such as the removal of taxes on dental prosthetics. Dr. Peters also outlines her goals for modernizing the House of Delegates process, including the creation of a "Resolution Dashboard" to help members track policy progress.

J Mich Dent Assoc March 2026

The Journal of the Michigan Dental Association

Each month, the Journal of the Michigan Dental Association delivers news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. It remains the main publication reaching Michigan dentists and is available worldwide through ADA Commons.

The March 2026 (Volume 108, No. 3) issue of the Journal is published in a digital format to provide updates and insights for Michigan's oral health community and MDA members. Print editions occur every other month beginning with January.

This issue includes feature articles on Most-Asked Dental Benefit Questions, an interview with ADA Speaker Dr. Deb Peters, …

The Clear Custom Matrix Technique For Class Ii Light-Cured Composites, James C. Hamilton, Dds

The Journal of the Michigan Dental Association

This clinical article details the Clear Custom Matrix Technique (CCMT), an innovative method for placing posterior composite restorations. The technique uses a pre-operative PVS impression to act as a die, reforming unset composite to precisely match the tooth's original anatomy. The author provides a step-by-step guide, demonstrating how the method saves chair time, reduces the need for finishing and polishing, and eliminates the air-inhibited layer. The article also discusses matrix selection, layering techniques, and troubleshooting common clinical challenges to achieve highly accurate and aesthetic results.

Dentistry Is The Life For Me, Michelle C. Dziurgot

The Journal of the Michigan Dental Association

In this editorial, the author reflects on her long career in dentistry and shares recent experiences with practice management and technological upgrades. She details the challenging but successful process of renegotiating PPO contracts to improve reimbursement rates and the financial benefits of moving to a more efficient office space. The author also highlights the clinical benefits of new equipment, such as a hand-held X-ray unit, and expresses her continued passion for the profession. The piece serves as both a personal reflection and an encouragement to colleagues to find joy and efficiency in their practices.

News You Need, David Foe

The Journal of the Michigan Dental Association

This comprehensive news section covers a wide range of association updates, including previews of the 2026 Annual Session and the Mission of Mercy volunteer event. It provides critical "Dental Benefit Briefs" regarding claims appeals, CMS rule changes for prior authorization, and code deletions affecting reimbursement. The source also features a Q&A with the new ADA 9th District Trustee and highlights new guidelines for using generative AI in dental journalism. Additionally, it reports on community grants and charitable programs like Livingston District’s "Gold for Food".

Endorsed Programs News, Reva Darling

The Journal of the Michigan Dental Association

This section provides updates on services and resources endorsed by the MDA to help members succeed in practice. It covers critical compliance topics like OSHA employee alarm standards and emergency evacuation procedures. Financial advice is offered for associates looking to purchase a practice, focusing on credit scores and debt management. Additionally, it promotes tools for increasing revenue through PPO negotiation and lowering insurance costs via risk management training. The source also mentions the availability of free, confidential counseling through the MDA Member Assistance Program.

When Toxic Behaviors Sneak Into Practice, Amrita Patel, Dds

The Journal of the Michigan Dental Association

This article addresses the challenge for new dentists in identifying and managing toxic workplace behaviors. It details common red flags such as chronic negativity, poor communication, "blame culture," and excessive production pressure that compromises ethics. The author explains how these environments can lead to burnout and practicing defensively rather than confidently. The source emphasizes the importance of developing self-awareness, seeking external mentorship, and establishing professional boundaries. It concludes that recognizing when to leave an unhealthy practice is an act of professional self-respect and essential for long-term career satisfaction.

The Back Page: Helping The Homeless Through The Delonis Oral Health Initiative, Sarah Tomaka, Dds

The Journal of the Michigan Dental Association

This feature story highlights a student-led initiative at the University of Michigan School of Dentistry to provide dental care to Ann Arbor's unhoused population. Through the Delonis Oral Health Initiative, students have partnered with a local shelter to connect over 100 vulnerable patients with essential treatment. The article discusses the profound impact of treating dental pain on an individual's ability to pursue stable housing and a better life. It also showcases how the program provides students with meaningful leadership and community service experience while addressing a critical gap in public health.

Exploring Adolescent Hearing Aid Usage And Appearance Of Psychiatric Symptoms In Adolescents Using Hearql-28 Surveys, Courtney J. Austin, Dylan Chan

MEDI 9331 Scholarly Activities Clinical Years

Approximately 2% of DHH people in need of mental health services actually receive these services. Among pediatric hearing loss populations, co-occurring cognitive and physical impairments are risk factors for poor mental health status. Due to language barriers and isolation, more children with hearing loss do not have access to mental health services. Cochlear implants have been shown to improve mental health status among the DHH population. Current literature focuses on the mental health status of children with cochlear implants, with little focus on hearing aid users. Using HEAR28 data and surveys, we can quantify the incidence of psychiatric symptoms among …

Does Genetic Testing Influence Outcomes: Early Experience In Melanoma Case Series, Ryan Reyes, George Skenteris, Stella Coker Watson Self Ph.D., Ms, Christine Marie-Gilligan Schammel, Steven D. Trocha

Faculty Publications

Background:

The treatment and prognosis of melanoma have historically been based on histologic stage and Breslow depth; however, due to the increase in surveillance, melanomas are being identified at an earlier stage and lower Breslow depth. Advances in genetic testing, such as Decision Dx®, mean that melanoma diagnostic decisions and prognosis can now be directed by genetics. The purpose of this project was to assess the influence of a Decision Dx® high-grade (Class 2A/B) classification on the treatment of melanoma patients at a regional medical center, particularly those not deemed high risk by conventional classification methods, including Breslow depth and …

Screening Ptsd In Clinical Populations Within East Africa: Results From The First Follow-Up Study Of Neurogap-Psychosis, Shaili Jha, Rocky Stroud, Ana Lucia Dice, Joseph Kyebuzibwa, Stella Gichuru, Fredrick Ochieng, Manasi Sharma, Hayden Mountcastle, Lydia Marshall, Lukoye Atwoli

Brain and Mind Institute

Background: Given the high burden of trauma in Sub-Saharan Africa, there is a critical need for scalable tools to screen for trauma and posttraumatic stress disorder (PTSD) symptoms, especially in low-resource settings.

Objective: This study aimed to evaluate the utility, reliability, and validity of the Primary Care PTSD Screen for DSM-5 (PC-PTSD-5) administered over the telephone to individuals previously enrolled in the Neuropsychiatric Genetics of African Populations-Psychosis study (NeuroGAP-Psychosis) study in Uganda (N = 4,921) and Kenya (N = 3,149).

Method: Cases with psychosis and controls without psychosis (patients, caretakers, or employees) were recontacted from the NeuroGAP-Psychosis …

Cultivating The Future Of Dentistry: Evolution Of Dental Education, Eric Mediavilla Dds, Fagd

Metro Denver Dental Society Articulator Magazine

This article explores how dental education and practice are rapidly changing with rising enrollment, growing female representation, and advanced digital technologies like VR simulators, 3D scanning and AI imaging. As educators balance innovation with foundational techniques, dentistry continues to evolve.