Medicine and Health Sciences Commons^™

Michigancovid19testingcollection, Michigan Department Of Health & Human Services

Michigan COVID-19 Testing Turnaround Data

This is a zipped file of all the pdfs uploaded to this collection, spanning from 2020-04-09 through 2021-05-28.

It also includes a comma separated file that lists the metadata for each file, including the file name within the Michigan COVID-19 Testing Turnaround Data ScholarWorks Collection (ScholarWorksFileTitle), the archived URL (InternetArchiveLink), the description of the file within the Michigan COVID-19 Testing Turnaround Data ScholarWorks Collection (ScholarWorksAbstract), and any additional comments about the file within the Michigan COVID-19 Testing Turnaround Data ScholarWorks Collection (ScholarWorksComments).

Identification Of Potential Non-Invasive Biomarkers In Diastrophic Dysplasia, Chiara Paganini, Ricki S. Carroll, Chiara Gramegna Tota, Andrea J. Schelhaas, Alessandra Leone, Angela L. Duker, David A. O'Connell, Ryan F. Coghlan, Brian Johnstone, Carlos R. Ferreira, Sabrina Peressini, Riccardo Albertini, Antonella Forlino, Luisa Bonafé, Ana Belinda Campos-Xavier, Andrea Superti-Furga, Andreas Zankl, Antonio Rossi, Michael B. Bober

Student Papers, Posters & Projects

Diastrophic dysplasia (DTD) is a recessive chondrodysplasia caused by pathogenic variants in the SLC26A2 gene encoding for a cell membrane sulfate/chloride antiporter crucial for sulfate uptake and glycosaminoglycan (GAG) sulfation. Research on a DTD animal model has suggested possible pharmacological treatment approaches. In view of future clinical trials, the identification of non-invasive biomarkers is crucial to assess the efficacy of treatments. Urinary GAG composition has been analyzed in several metabolic disorders including mucopolysaccharidoses. Moreover, the N-terminal fragment of collagen X, known as collagen X marker (CXM), is considered a real-time marker of endochondral ossification and growth velocity and was studied …

Michigancovid19vaccinecollection, Michigan Department Of Health & Human Services

Michigan COVID-19 Vaccine Data

This is a zipped file of all the pdfs uploaded to this collection, spanning from 2020-12-16 through 2023-04-26. It also includes a few additional pdfs: 2020-10-16_Michigan_COVIDVaccination_Plan.pdf; 2020-12-13_Michigan_COVIDVaccination_PrioritizationGuidance.pdf; 2020-12-13_Michigan_COVIDVaccine_FAQ.pdf; 2020-12-13_Michigan_COVIDVaccine_Infograph.pdf; 2021-01-21_Michigan_COVIDVaccine_Locations.pdf.

The zip file also includes a comma separated file that lists the metadata for each file, including the file name within the Michigan COVID-19 Vaccine Data ScholarWorks Collection (ScholarWorksFileTitle), the archived URL (InternetArchiveLink), the description of the file within the Michigan COVID-19 Vaccine Data ScholarWorks Collection (ScholarWorksAbstract), and any additional comments about the file within the Michigan COVID-19 Vaccine Data ScholarWorks Collection (ScholarWorksComments).

Michigancovid19outbreakreportcollection, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

This is a zipped file of all the pdfs uploaded to this collection, spanning from 2020-08-20 through 2023-04-27 for the overall outbreak reports, 2020-09-14 through 2022-06-13 for school outbreak reports, and 2022-06-21 through 2023-04-25 for ISD K-12 outbreak reports.

The zip file also includes a comma separated file that lists the metadata for each file, including the file name within the Michigan COVID-19 Outbreak Reports ScholarWorks Collection (ScholarWorksFileTitle), the archived URL (InternetArchiveLink), the description of the file within the Michigan COVID-19 Outbreak Reports ScholarWorks Collection (ScholarWorksAbstract), and any additional comments about the file within the Michigan COVID-19 Outbreak Reports ScholarWorks …

Functional Neurological Symptom Disorder: A Continuing Conundrum For The Perioperative Physician, Phillip Chin, Sangeeta Kumaraswami

NYMC Faculty Publications

Functional neurological symptom disorder (FNSD) or functional neurological disorder (FND) or conversion disorder, is a syndrome of neurological complications unexplained by neuropathology. The term FNSD or FND is now preferred, as conversion disorder is not an etiologically neutral term and is thus falling from use by researchers and clinicians in the field. We report a case of new-onset postoperative neurological deficit in a patient who had undergone uneventful general anesthesia for a urology procedure. Postoperatively, in the post-anesthesia care unit, the patient was found to be unable to move her upper and lower limbs. Organic pathology was excluded and a …

Penile Herpes Vegetans In A Patient With Well-Controlled Hiv, Kenneth Helmandollar, Natalie Distefano, Janet Moy

NYMC Faculty Publications

No abstract provided.

Incidence, Characteristics, And Outcomes Of Stroke In Pediatric Patients With Celiac Disease, Sima Vazquez, Akash Thaker, Bridget Nolan, Eris Spirollari, Kevin Clare, Steven Wolf, Patricia Mcgoldrick, Rolla Nuoman, Philip Overby, Fawaz Al-Mufti

NYMC Faculty Publications

(1) Background: Celiac disease (CD) can cause long-term inflammation and endothelial dysfunction and has been cited as a risk factor for acute ischemic stroke (AIS) in pediatric patients. However, the rate and outcomes of AIS in pediatric patients with CD has not been explored in a large population. Our objective is to explore the rate, severity, and outcomes of CD amongst pediatric AIS patients on a nationwide level. (2) Methods: The National Inpatient Sample (NIS) database was queried from 2016 to 2020 for pediatric patients with a principal diagnosis of AIS. Patients with a concurrent diagnosis of CD (AIS-CD) were …

Oncolytic Virotherapy For High-Grade Glioma And Current Evidence And Factors To Consider For Incorporation Into Clinical Practice, Sauson Soldozy, Daniel G. Eichberg, Alexis A. Morell, Evan Luther, Victor M. Lu, Dominique M. Higgins, Nitesh V. Patel, Ashish H. Shah, Simon J. Hanft, Ricardo J. Komotar, Michael E. Ivan

NYMC Faculty Publications

Brain tumor incidence is on the rise, and glioblastoma comprises the majority of primary tumors. Despite maximal safe resection and adjuvant chemoradiation, median survival for high-grade glioma remains poor. For this reason, it is important to develop and incorporate new treatment strategies. Oncolytic virotherapy has emerged as a viable new therapeutic entity to fill this gap. Preclinical research has shown oncolytic virotherapy to be a robust and effective treatment option for brain tumors, and clinical trials for both adult and pediatric high-grade glioma are underway. The unique and protected environment of the nervous system, in part due to the blood-brain …

The Impact Of Covid-19 On Hospitalization Outcomes Of Patients With Acute Myocardial Infarction In The Usa, F.E. Markson, E. Akuna, C.Y. Lim, L. Khemani, A, Amanullah

Einstein Health Papers

Background/study objective: The effect of the COVID-19 pandemic affected health care delivery, as it led to variable outcomes in different disease states including cardiovascular diseases. In this study, we evaluated the impact of coexisting COVID-19 on Acute Myocardial Infarction (AMI). Design/setting: We analyzed discharge records of AMI patients from the National Inpatient Sample (NIS) in the year 2020.

Main outcome measures: Using propensity score matching, we assessed the impact of COVID-19 infection on the in-hospital outcomes of patients presenting with AMI.

Results: There were 1154 patients with concomitant COVID-19 infection and AMI who were matched with 109,990 patients with AMI …

Impact Of Social Media And Multimedia Platforms: View From The Jacc: Case Reports Some Editors, Estefania Oliveros, Yevgeniy Brailovsky, Alessandro Beneduce, Hooman Bakshi, Edoardo Zancanaro, Indah Sukmawati, Mrinali Shetty, Gina Lundberg

Division of Cardiology Faculty Papers

No abstract provided.

Physical And Stressful Psychological Impacts Of Prolonged Personal Protective Equipment Use During The Covid-19 Pandemic: A Cross-Sectional Survey Study, Giuseppe Candido, Costanza Tortù, Chiara Seghieri, Riccardo Tartaglia, Chiara Baglioni, Paolo Citti, Ida Marina Raciti, Micaela La Regina, Silvia Simonini, Moira Urbani, Chiara Parretti, Paul Barach

College of Population Health Faculty Papers

BACKGROUND: Healthcare workers (HCWs) caring for COVID-19 infected patients are exposed to stressful and traumatic events with potential for severe and sustained adverse mental and physical health consequences. Our aim was to assess the magnitude of physical and mental health outcomes of HCWs due to the prolonged use of personal protective equipment (PPE) treating COVID-19 patients.

METHODS: This cross-sectional study assessed the symptoms of stress, anxiety, insomnia, and psychological resilience using the Stress and Anxiety to Viral Epidemics (SAVE) scale, Insomnia Severity Index (ISI), and Resilience Scale (RS), respectively, in Italy between 1st February and 31st March 2022. The physical …

Assessing Boil Water Notices As Health-Risk Communication: Risk Perceptions, Efficacy, And Compliance During Winter Storm Uri, Ashleigh M. Day, Sydney O'Shay, Khairul Islam, Matthew W. Seeger, Shawn P. Mcelmurry

Open Data at Wayne State

Winter Storm Uri was an extreme disaster that impacted much of the United States during February of 2021. Texas and Oklahoma were generally not prepared for such an event and experienced massive power grid failures. This led to cascading risks including water system disruptions and many boil water notices (BWNs). The breakdown of some communication channels and the inability to enact protective actions due to power outages, as well as travel limitations on public roads, complicated both dissemination and implementation. Under these conditions, a non-representative, cross-sectional, survey was collected to assess individuals experience BWNs and how perceived efficacy impacts compliance. …

Anesthetic Considerations Of Organ Procurement After Brain And Cardiac Death: A Narrative Review, Michael B. Brown, Apolonia E. Abramowicz, Peter J. Panzica, Garret Weber

NYMC Faculty Publications

Organ donation procedures have become more frequent in the US as the need for transplants is increasing. Defining the anesthesiologist's role in organ donations after brain and cardiac death is important, as is understanding its ethics and practical physiologic and perioperative implications. Despite this, there are few papers specifically addressing the anesthetic management of organ donors. This review summarizes the preoperative, intraoperative, and postmortem considerations for the anesthesiologist involved in organ donation after either brain or cardiac death. A search of the published literature was performed using PubMed, Excerpta Medica dataBASE (EMBASE), and Google Scholar in March of 2022 for …

Methicillin-Resistant Staphylococcus Aureus (Mrsa) Empyema Post-Covid Infection Causing Severe Septic Shock And Multiorgan Failure, Antony Arumairaj, Ali Safavi, Hossam Amin, Armeen Poor, Natoushka Trenard

NYMC Faculty Publications

Secondary bacterial infections post-COVID infection posed a major challenge to the healthcare settings during the COVID pandemic. We present the case of an 81-year-old patient who was initially admitted for COVID pneumonia in a tertiary care hospital and was managed with a course of dexamethasone and had a good outcome. However, post-discharge, the patient developed symptoms of productive cough, hemoptysis and shortness of breath. Evaluation of the patient revealed that the patient had developed a secondary bacterial infection with Methicillin-resistant Staphylococcus aureus (MRSA), resulting in MRSA pneumonia and empyema. The patient was started on appropriate antibiotics and underwent thoracocentesis followed …

Acute Inflammatory Arthropathy And Hypercalcemia Leading To A Diagnosis Of Primary Hyperparathyroidism In A Patient With Known Sarcoidosis, Kalee Larsen, Jenna Guma, Rime Mehannek, Michael Guma

NYMC Faculty Publications

Calcium pyrophosphate deposition disease (CPPD) is a crystal-induced arthropathy characterized by calcium pyrophosphate crystal deposition in joints and soft tissues. The diagnosis is suggested by the presence of chondrocalcinosis on x-ray but is most often diagnosed by synovial fluid analysis (SFA). CPPD is associated with aging and metabolic disorders such as hyperparathyroidism. In this case, we present an 87-year-old woman with known sarcoidosis who presented with acute arthropathy, hypercalcemia, and radiographic evidence of CPPD. Her hypercalcemia had been attributed to her sarcoidosis in the past without a full workup. Hypercalcemia in the setting of suspected CPPD led to a full …

The Impact Of Post-Covid-19 Syndrome In Adolescents: A Pilot Study, Jane El Khoury, May Skoury, Marc Y. El Khoury

NYMC Faculty Publications

BACKGROUND: Post-COVID-19 syndrome has emerged as a long-term complication in adults and children; its effect on adolescents' performance in school is not well studied. OBJECTIVES: To study the physical/psychological impact of prolonged post-COVID-19 symptoms on school performance. METHODS: This is a cross-sectional study using Google Forms, a web-based fully anonymized survey of children in grades 10-12. RESULTS: The study included 54 students with a mean age of 16 years of whom 32 had COVID-19. Two were hospitalized and 10 had symptoms lasting more than four weeks. Commonly reported chronic symptoms were fatigue and cough. Seven students quit sports; eight had …

Michigancovid19longtermcaredatacollection, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

This is a zipped file of all the pdfs uploaded to this collection, spanning from 2020-04-24 through 2023-04-25.

It also includes a comma separated file that lists the metadata for each file, including the date it was captured (CheckedEST), the archived URL (InternetArchiveLink), the date that the website was updated (WebsiteUpdate), information included on the website (Website Notes), the file name within the Michigan COVID-19 Long Term Care Data ScholarWorks Collection (ScholarWorksFileTitle), the description of the file within the Michigan COVID-19 Long Term Care Data ScholarWorks Collection (ScholarWorksAbstract), and any additional comments about the file within the Michigan COVID-19 Long …

Differential Response Of C9orf72 Transcripts Following Neuronal Depolarization, Layla T. Ghaffari, Davide Trotti, Aaron R. Haeusler

Farber Institute for Neuroscience Faculty Papers

The (G4C2)n nucleotide repeat expansion (NRE) mutation in C9orf72 is the most common genetic cause of ALS and FTD. The biological functions of C9orf72 are becoming understood, but it is unclear if this gene is regulated in a neural-specific manner. Neuronal activity is a crucial modifier of biological processes in health and neurodegenerative disease contexts. Here, we show that prolonged membrane depolarization in healthy human iPSC-cortical neurons leads to a significant downregulation of a transcript variant 3 (V3) of C9orf72, with a concomitant increase in variant 2 (V2), which leads to total C9orf72 RNA transcript levels remaining unchanged. However, the …

Michigancovid19hospitalcollection, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

This is a zipped file of all the pdfs uploaded to this collection, spanning from 2020-04-02 through 2023-04-28.

It also includes a comma separated file that lists the metadata for each file, including the file name within the Michigan COVID-19 Hospital Data ScholarWorks Collection (ScholarWorksFileTitle), the archived URL (InternetArchiveLink), the description of the file within the Michigan COVID-19 Hospital Data ScholarWorks Collection (ScholarWorksAbstract), and any additional comments about the file within the Michigan COVID-19 Hospital Data ScholarWorks Collection (ScholarWorksComments).

Acute Diplopia After Glabellar Hyaluronic Acid Filler Injection, Caroline W. Chung, Eric J. Shiuey, César A. Briceño, Vivian Lee

SKMC Student Presentations and Publications

Purpose: Blindness is a well-known complication of filler injection in the glabellar region. Acute diplopia from filler injection without vision loss is a rare complication that typically results in clinical ophthalmoplegia which can have permanent sequelae. Here, we describe a patient who presented with acute diplopia with grossly intact full extraocular motility after glabella hyaluronic acid filler injection that resolved after 1 month.

Observations: A previously healthy 43-year-old woman underwent her first hyaluronic acid injection in the glabella and developed immediate binocular double vision with severe pain and skin mottling above her right eyebrow and central forehead. Hyaluronidase injections, nitroglycerin …

Modeling Honeymoon And Divorce Effects In Wolbachia Control Trials Of Dengue, Casey P. O'Brien

Biology and Medicine Through Mathematics Conference

No abstract provided.

Dailymichigancovid19collection, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

This is a zipped file of all the pngs uploaded to this collection, spanning from 2020-03-04 through 2023-04-25.

Automated Subfield Volumetric Analysis Of Amygdala, Hippocampus, And Thalamic Nuclei In Mesial Temporal Lobe Epilepsy, Arichena Manmatharayan, Michael Kogan, Caio Matias, Mashaal Syed, India Shelley, Amar Chinni, Kichang Kang, Kiran Talekar, Scott H. Faro, Feroze B. Mohamed, Ashwini Sharan, Chengyuan Wu, Mahdi Alizadeh

Department of Neurosurgery Faculty Papers

Purpose: Identifying relationships between clinical features and quantitative characteristics of the amygdala-hippocampal and thalamic subregions in mesial temporal lobe epilepsy (mTLE) may offer insights into pathophysiology and the basis for imaging prognostic markers of treatment outcome. Our aim was to ascertain different patterns of atrophy or hypertrophy in mesial temporal sclerosis (MTS) patients and their associations with postsurgical seizure outcomes. To assess this aim, this study is designed in 2 folds: (1) hemispheric changes within MTS group and (2) association with postsurgical seizure outcomes.

Methods and materials: 27 mTLE subjects with mesial temporal sclerosis (MTS) were scanned for conventional 3D …

Impact Of The Covid-19 Pandemic On The Management Of Risk Factors In Patients With Stable Atherosclerotic Vascular Disease, Dean Karalis, Patrick Moeller, Albert Crawford, Maria Janelli, Scott Hessen

Division of Cardiology Faculty Papers

Background

Effective control of risk factors in patients with ASCVD is important to reduce recurrent cardiovascular events. However, many ASCVD patients do not have their risk factors controlled, and this may have worsened during the COVID-19 pandemic.

Methods

We retrospectively evaluated risk factor control among 24,760 ASCVD patients who had at least 1 outpatient encounter both pre-pandemic and during the first year of the pandemic. Risk factors were uncontrolled if the blood pressure (BP) ≥ 130/80 mm Hg, LDL-C ≥ 70 mg/dL, HgbA1c ≥ 7 for diabetic patients, and patients were current smokers.

Results

During the pandemic, many patients had …

Hearing Aid Fitting Software Manipulations, Fadi Najem

Pacific Open Texts

This learning module is suitable for Doctor of Audiology students at the intermediate level of their learning about amplification. The module provides a comprehensive and interactive guideline for hearing aid finetuning and troubleshooting patients’ complaints regarding hearing aids. The module also provides a quick guide on how to set the hearing aids in test mode for test box measurements and how to locate data sheets for selected manufacturers.

Determining The Need For Additional Testing With Quantiferon Tb Gold In Patients With Positive Tuberculin Skin Tests And A History Of Bcg Vaccination, Antony J. Arumairaj, Hansang Park, Fernando Quesada, Brian Altonen, Shobhana Chaudhari, Joseph Mattana, Imnett Habtes

NYMC Faculty Publications

OBJECTIVE: To determine if the QuantiFERON-TB Gold (QFT) testing can be obviated for the diagnosis of latent tuberculosis infection (LTBI) in patients with a positive tuberculin skin test (TST) and a history of Bacillus Calmette-Guerin (BCG) vaccination by identifying high-risk features in patients with positive TST and a history of BCG vaccination who are associated with positive QFT. METHODS: Retrospective chart review was done for 76 adult patients by dividing them into two groups. Group 1 consisted of true positive TST patients who had BCG vaccination and were positive for QFT. Group 2 consisted of false positive TST patients who …

Gestational Transient Thyrotoxicosis Complicated By Thyroid Storm In A Patient With Hyperemesis Gravidarum, Camila A. Villavicencio, Alberto Franco-Akel, Regina Belokovskaya

NYMC Faculty Publications

We describe a patient with gestational transient thyrotoxicosis (GTT) associated with hyperemesis gravidarum (HG) in a twin gestation complicated by thyroid storm resulting in intrauterine fetal demise. GTT is a well-documented complication of the first trimester of pregnancy that may affect up to 60% of pregnancies with HG. Typically, GTT is not associated with unfavorable maternal or fetal outcomes and has a spontaneous resolution. Aside from supportive care, the use of antithyroid drugs (ATD) in GTT is not regularly recommended. Although to our knowledge one similar case has been reported in the literature, the incidence of thyroid storm in GTT …

Publication Rates Of Abstracts Presented Across 6 Major Spine Specialty Conferences, Tariq Z. Issa, Yunsoo Lee, Mark J. Lambrechts, Christopher Reynolds, Ryan Cha, James Kim, Jose A. Canseco, Alex R. Vaccaro, Christopher K. Kepler, Gregory D. Schroeder, Alan S. Hilibrand

Rothman Institute Faculty Papers

Background: Although scientific researchers aim to present their projects at academic conferences as a step toward publication, not all projects mature to become a peer-reviewed manuscript. The publication rate of meetings can be utilized to assess the quality of presented research. Our objective was to evaluate the contemporary publication rate of abstracts presented at spine conferences.

Methods: We reviewed annual meeting programs of North American Spine Society (NASS), Scoliosis Research Society (SRS), International Meeting on Advanced Spine Techniques (IMAST), Spine Global Spine Congress (GSC), Lumbar Spine Research Society (LSRS), and Cervical Spine Research Society (CSRS) from 2017 to 2019. Abstracts …

Incidence And Risk Factors For Retinal Detachment And Retinal Tear After Cataract Surgery: Iris® Registry (Intelligent Research In Sight) Analysis, Michael J. Morano, M. Ali Khan, Qiang Zhang, Colleen P. Halfpenny, Douglas M. Wisner, James Sharpe, Alexander Li, Maurizio Tomaiuolo, Julia A A. Haller, Leslie Hyman, Allen C. Ho

Wills Eye Hospital Papers

Objective To report the incidence of and evaluate demographic, ocular comorbidities, and intraoperative factors for rhegmatogenous retinal detachment (RRD) and retinal tear (RT) after cataract surgery in the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight).

Design Retrospective cohort study.

Participants Patients aged ≥ 40 years who underwent cataract surgery between 2014 and 2017.

Methods Multivariable logistic regression was used to evaluate demographic, comorbidity, and intraoperative factors associated with RRD and RT after cataract surgery.

Main Outcome Measures Incidence and risk factors for RRD or RT within 1 year of cataract surgery.

Results Of the 3 177 195 …

Effects Of Pregnancy And Progesterone On Atrial Fibrillation, Heloisa M. Rutigliano

Browse all Datasets

Atrial Fibrillation (AF) is the most common cardiac arrythmia in adults with likely sex-specific risk factors. Female sex hormones may be important in modulating risk for atrial fibrillation. We hypothesize that pregnancy and progesterone (P4), a hormone found in high levels during pregnancy with abrupt withdrawal immediately after parturition, modulates AF susceptibility in female goats. Cardiac specific TGF-?1 transgenic female goats and age-matched wild-type (WT) female goats were utilized. Pacemakers were implanted in all animals for continuous arrhythmia monitoring and AF inducibility. AF inducibility was evaluated using 5 separate 10 s bursts of atrial pacing (160 - 200 ms). In …