Medicine and Health Sciences Commons^™

A Mathematical Model Of The Opioid Epidemic In The State Of Maine, Cole Butler

Honors College

For the past two decades the United States has been embroiled in a prescription drug epidemic that has since grown in magnitude and complexity. The ripples of this epidemic have been especially apparent in the state of Maine, which has fought hard to mitigate the damage caused by addiction to pharmaceutical and illicit opioids. Us- ing data from state and federal sources, we construct a mathematical model capturing the dynamics of the opioid epidemic in the state of Maine, specifically as it pertains to pharmaceutical opioids and heroin. Parameter fitting is performed followed by an uncertainty analysis to quantify potential …

Life Experiences Associated With Change In Perpetration Of Domestic Violence., Avanti Adhia, Vivian H Lyons, Hannah Cohen-Cline, Ali Rowhani-Rahbar

Articles, Abstracts, and Reports

BACKGROUND: This study assessed whether several adult life experiences, including loss of support, loss of food security, loss of housing, and substance use cessation, are associated with change in domestic violence (DV) perpetration from early to later adulthood. Using 2015 to 2016 cross-sectional, self-report survey data from Medicaid enrollees in Oregon (N = 1620), we assessed change in DV perpetration from early adulthood (19-30 years) to later adulthood (≥ 31 years of age), cut points determined by existing survey questions. Multinomial logistic regression models were constructed to estimate the association between life experiences and physical DV perpetration using odds ratios …

Group Treatment Effectiveness For Substance Use Disorders: Abstinence Vs. Harm Reduction, Jill D. Parramore

Counseling & Human Services Theses & Dissertations

The purpose of this systematic review and meta-analysis was to compare group treatment effectiveness for substance use disorders within the U.S. across treatment philosophies as it relates to the primary research question, Is there a significant difference of group treatment effectiveness between Abstinence and Harm Reduction treatment philosophies? It was hypothesized that group treatment will remain an effective intervention to treat substance use disorders between treatment philosophies and that no significant differences exist between-group comparisons. The aim of this study is to provide evidence of treatment effectiveness that will ultimately improve treatment outcomes for substance use disorders, provide guidance for …

Diet, Nutrition, And Substance Use Disorder, Mateja R. Savoie-Roskos, Ashley Yaugher, Alise Williams Condie, Gabriela Murza, Maren Wright Voss, Kandice Atisme

All Current Publications

Consuming a healthy diet can benefit everyone—especially individuals with substance use disorder (SUD), a disorder that occurs when frequent use of drugs or alcohol causes impairment, health issues, and difficulties with managing daily responsibilities (Substance Abuse and Mental Health Services Administration [SAMHSA], 2020). Although often overlooked, nutrition can play a key role in the treatment and recovery process for individuals with SUD, and should be included as part of a holistic approach toward recovery. In this fact sheet we will review how diet and nutrition are impacted during an active addiction, and the influence nutrition can have on treatment and …

Managing Substance Use Disorder Through A Walking/Running Training Program, Chia-Liang Dai, Ching-Chen Chen, George B. Richardson, Howard R. D. Gordon

College of Education Faculty Research

While emerging studies have demonstrated the benefit of exercise in Substance Use Disorder (SUD) recovery outcomes, lack of motivation to engage in exercise has been indicated as one of many perceived barriers that contribute to low recruitment and adherence rates in SUD treatment. The current study aimed to explore participants’ perceptions of attending a supervised exercise program (boot camp workouts, walking/running practice, and a race event) while in treatment for SUD. A total of 109 participants were recruited to a 14-week exercise training program and 61 chose to participate in, and completed, a race at the close of the program. …

Post-Traumatic Stress And Marijuana Outcomes: The Mediating Role Of Marijuana Protective Behavioral Strategies, Hallie R. Jordan, Michael B. Madson, Adrian J. Bravo, Matthew R. Pearson

Faculty Publications

Background: The present study investigated the mediating role of protective behavioral strategies for marijuana (PBSM) on the relationship between posttraumatic stress disorder (PTSD) and marijuana outcomes (i.e. marijuana use frequency, marijuana use quantity, cannabis use disorder (CUD) symptoms, and marijuana-related problems).

Methods: Participants were 1,107 traditional age college students (M_age = 20.26, SD = 3.32; 66.5% White, non-Hispanic; 68.8% female), who reported consuming marijuana at least once in the last 30 days and completed measures of PTSD symptoms, PBSM, and marijuana-related outcomes.

Results: PBSM significantly mediated the positive relationships between PTSD symptoms and both CUD symptoms and marijuana-related …

The Other Epidemic, Bruce Deighton

HCA Healthcare Journal of Medicine

The epidemic level of opioid abuse in the U.S. population continues to present a major challenge to our society and to the medical profession. Medical education has a significant role in improving screening, diagnosis, appropriate treatment and management of opioid use disorder. Addressing the problem of overprescribing opioids through physician education, surveillance and opioid management has resulted in significant improvement, translating to fewer overdose deaths from prescription opioids. Graduate medical education can increase access to care by training more addiction medicine specialists, and training other physicians to prescribe buprenorphine and provide access to medically assisted care.

Does Early Physical Therapy Intervention Reduce Opioid Burden And Improve Functionality In The Management Of Chronic Lower Back Pain?, Shedrick Martin, Kimberly Tallian, Victoria T Nguyen, Jason Van Dyke, Harminder Sikand

Articles, Abstracts, and Reports

Introduction: Chronic lower back pain is a leading cause of disability in US adults. Opioid use continues to be controversial despite the Centers for Disease Control and Prevention guidance on chronic pain management to use nonpharmacologic and nonopioid pharmacologic interventions. The objectives of the study were to assess the impact of early physical therapy (PT) intervention on improving functionality and reducing opioid burden in patients with chronic lower back pain.

Methods: A single-center, retrospective chart review of patients receiving ≥6 PT visits and treated with either opioids first (OF) or PT first (PTF) therapy for chronic lower back pain were …

Impact Of Social Networks, Mental Health, And Sobriety On Exercise Within A Collegiate Recovery Community, Megan S. Patterson, Alex Russell, Mandy Nicole Spadine, Tyler Prochnow, Katie M. Heinrich

Health Behavior Research

Exercise is especially beneficial for individuals recovering from addiction. In addition to improved physical, emotional, and mental health, exercise is linked to long-term recovery for those overcoming addiction. With nearly 10% of college students in recovery, and many utilizing campus resources such as collegiate recovery communities (CRCs) to support their recovery, it is important to understand the relationship between exercise and the recovery process among college students. The purpose of this study was to use social network analysis and theory to understand exercise behaviors among a group of college students in recovery. The relationship between exercise and sobriety, mental health …

Feasibility And Acceptability Of A Culturally- And Linguistically-Adapted Smoking Cessation Text Messaging Intervention For Latino Smokers., Francisco Cartujano-Barrera, Lisa Sanderson Cox, Evelyn Arana-Chicas, Mariana Ramírez, Jaime Perales-Puchalt, Pamela Valera, Francisco J. Díaz, Delwyn Catley, Edward F. Ellerbeck, Ana Paula Cupertino

Manuscripts, Articles, Book Chapters and Other Papers

Objective: Assess the feasibility and acceptability of a culturally- and linguistically-adapted smoking cessation text messaging intervention for Latino smokers. Methods: Using a community-based strategy, 50 Latino smokers were recruited to participate in a smoking cessation pilot study. Participants received a 12-week text messaging intervention and were offered Nicotine Replacement Therapy (NRT) at no cost. We assessed biochemically verified abstinence at 12 weeks, text messaging interactivity with the program, NRT utilization, self-efficacy, therapeutic alliance, and satisfaction. Results: Participants were 44.8 years old on average (SD 9.80), and they were primarily male (66%) and had no health insurance (78%). Most of the …

Validation Of A Brief Pornography Screen Across Multiple Samples, Shane W. Kraus, Mateusz Gola, Joshua B. Grubbs, Ewelina Kowalewska, Rani A. Hoff, Michał Lew-Starowicz, Steve Martino, Steven D. Shirk, Marc N. Potenza

Psychology Faculty Research

Background and Aims To address current gaps around screening for problematic pornography use (PPU), we initially developed and tested a six-item Brief Pornography Screen (BPS) that asked about PPU in the past six months. Methods and Participants We recruited five independent samples from the U.S. and Poland to evaluate the psychometric properties of the BPS. In Study 1, we evaluated the factor structure, reliability, and elements of validity using a sample of 224 U.S. veterans. One item from the BPS was dropped in Study 1 due to low item endorsement. In Studies 2 and 3, we further investigated the five-item …

The Development Of The Compulsive Sexual Behavior Disorder Scale (Csbd-19): An Icd-11 Based Screening Measure Across Three Languages, Beáta Bőthe, Marc N. Potenza, Mark D. Griffiths, Shane W. Kraus, Verena Klein, Johannes Fuss, Zsolt Demetrovics

Psychology Faculty Research

Background Compulsive Sexual Behavior Disorder (CSBD) is included in the eleventh edition of The International Classification of Diseases (ICD-11) as an impulse-control disorder. AimsThe aim of the present work was to develop a scale (Compulsive Sexual Behavior Disorder Scale–CSBD-19) that can reliably and validly assess CSBD based on ICD-11 diagnostic guidelines. Method Four independent samples of 9,325 individuals completed self-reported measures from three countries (the United States, Hungary, and Germany). The psychometric properties of the CSBD-19 were examined in terms of factor structure, reliability, measurement invariance, and theoretically relevant correlates. A potential threshold was determined to identify individuals with an …

Stigma, Help Seeking, And Substance Use, Daniel Gutierrez, Allison Crowe, Patrick R. Mullen, Laura Pignato, Shuhui Fan

Arts & Sciences Articles

Researchers used path analysis to examine self-stigma, help seeking, and alcohol and other drug (AOD) use in a community sample of individuals (N = 406) recruited through the crowdsourcing platform MTurk. Self-stigma of help seeking contributed to AOD use and was mediated by help-seeking attitudes. We discuss the implications for advocacy and stigma reduction in substance use treatment. Counselors and counselor educators can implement and advocate for interventions and training that increase positive attitudes toward seeking help, such as providing appropriate training with supervisees and counselors-in-training, providing clients and the community with mental health literacy, and engaging in more advocacy. …

Identifying And Managing Substance Abuse In The Emergency Department, Nelsy M. Zuniga

College of Pharmacy Student Research

No abstract provided.

What Are The Relationships Between Adverse Childhood Experiences And Age Of Initiaton Of Substance Use?, Alisha Dozier

Electronic Theses, Projects, and Dissertations

ABSTRACT

Child abuse and substance abuse are significant health problems in the United States and they negatively impact the physical, emotional, and biological health of millions of individuals. It is estimated that one in four children experience child abuse, which is a risk factor for the development of substance abuse problems later in life (U.S. Department of Health and Human Services [HHS], 2018). Rates of substance abuse are increasing nationally, making the relationship between child abuse and the development of substance abuse problems important to study.

This research project analyzes the relationship between adverse childhood experiences and subsequent age of …

Barriers And Facilitators To Opioid Use Treatment And Recovery Services During Pregnancy, Loralie Woods

Dissertations

Purpose: To identify barriers and facilitators to opioid use treatment and recovery services among pregnant and nonpregnant women who misuse opioids.

Background: Over 130 Americans die daily after overdosing on opioids. Women have not been immune from opioid use disorders (OUDs), with a 4-fold increase from 1999-2010. The prevalence of opioid use among pregnant women increased from 1.5 per 1,000 hospital deliveries to 6.5. Although the annual National Surveys on Drug Use and Health (NSDUH) has provided information on risk factors for OUD related to socioeconomic and demographic factors, no studies using this data have identified barriers to opioid use …

A Follow-Up Phone Call To Post-Operative Patients Using The Five A’S, Brittney Ochs

Doctor of Nursing Practice Final Manuscripts

Abstract

Background: The 2016 National Survey on Drug Use and Health reported that 53 percent of people that misused pain relievers in the past year received them from a friend or relative. The NIDA describes that from 2002 to 2008 that drug abuse in service members went from 2% to 11%. Often patients are initially prescribed and introduced to opioid medication for acute pain. One such circumstance is in the perioperative period that could provide an opportunity to promote opioid-sparing techniques to reduce the exposure to opioids.

Purpose of Project: To assess discharge medication characteristics and reinforce discharge medication instructions …

The Stories Behind The Struggle: A Closer Look At First Experiences With Opioid Misuse, Khary K. Rigg, Shannon M. Monnat, Katherine Mclean, Ashton Verdery, Glenn Sterner

Population Health Research Brief Series

The opioid crisis is a national public health emergency. Over 47,000 people in the U.S. died of opioid overdoses in 2017. Improving our knowledge about how people first come to misuse opioids can help to inform prevention and treatment interventions. This research brief shows that opioid misuse most often begins before age 25, most people obtain the opioids they misuse from friends and family rather than a health care provider, and experimenting and coping with life stressors are the most common motivations for starting opioid misuse.

Substance Use Prevention Services In Juvenile Justice And Behavioral Health: Results From A National Survey, Rodney Funk, Hannah K. Knudsen, Larkin S. Mcreynolds, John P. Bartkowski, Katherine S. Elkington, Ellen H. Steele, Jessica M. Sales, Christy K. Scott

Behavioral Science Faculty Publications

BACKGROUND: This study examined the national availability of substance use prevention (SUP) within juvenile justice (JJ) and their primary behavioral health (BH) providers, and the relationships between the availability of SUP and agency-level measures of organizational structure, staffing, and youth characteristics. A three-stage national probability sampling process was used to select participants for a national survey that included, among other facets of community supervision (CS) and BH practices, questions on agency characteristics, youth characteristics, whether the agency/provider directly provided SUP services, and whether the agency/provider directly provided substance use and/or mental health treatment. This paper focuses on SUP services along …

The Effects Of Motivational Interviewing For Those Afflicted With Opioid Addiction, Kathy Roberts

Evidence-Based Practice Project Reports

Substance use disorders are a worldwide problem, according to the Center for Disease Control (CDC) there were 70,237 drug overdose deaths that occurred in the United States in 2017, of which 47,600 were opioid related. Illinois had a 14.3% increase of opioid deaths from 2016-2017 (CDC, 2017). Numerous interventions exist to address this health concern, yet evidence shows that Motivational Interviewing (MI) was the most efficient and effective way to promote behavioral change. The purpose of this EBP project was to provide evidence that MI increased referrals and promoted compliance with appointments to treatment programs. The sample for this project …

2020 County Health Rankings Tennessee Data And Updated Substance Abuse 2005-2019, Kelsey L. Grabeel, Jenny Moore

Faculty Publications

No abstract provided.

Identification And Management Of Adolescent Alcohol Use: Screening And Motivational Interviewing, Kelsie L. Berger

Evidence-Based Practice Project Reports

Adolescent alcohol consumption is a serious health problem in the United States. Alcohol is the most widely used substance, and it continues to be the drug of choice for adolescents (CDC, 2018). Over 7 million adolescents and approximately 30 percent of high school students in the U.S. that admit to drinking more than a few sips of alcohol in the past 30 days (NIAAA, n.d.). Underage alcohol use can lead to many complications such as social, school, and legal problems, and when initiated early in life is associated with the development of alcohol use disorder (NIAAA, n.d.). The purpose of …

Polysubstance Exposure And Its Relationship To Pharmacological Treatment Characteristics, Parker Miller

Undergraduate Honors Theses

Neonatal Abstinence Syndrome (NAS) remains an ever-growing public health issue and a continued avenue for future research. The research question for this retrospective study was whether polysubstance exposure is related to the dose of medication the infant received or to the number of opioid-medications required to treat the infants’ withdrawal symptoms? The hypothesis for the retrospective study was there will be a significant relationship between polysubstance exposure and the dose of medication the infant received as well as the number of opioid-medications required to treat the infants’ withdrawal symptoms. A bivariate correlational indicated that there was not a significant association …

Acute Disseminated Encephalomyelitis, Ashan Hatharasinghe, Hossein Akhondi, Don Pepito

HCA Healthcare Journal of Medicine

Introduction: Acute Disseminated Encephalomyelitis (ADEM) is a rare autoimmune demyelinating disorder of the central nervous system. Clinical manifestations include encephalopathy, motor deficits, ataxia, and meningeal signs. In most cases, ADEM is preceded by either vaccination or viral illness. Here, we present a case with neither of the two predisposing elements.

Discussion: A 28-year-old Hispanic female presenting with substance use and suicidal ideation was placed on an involuntary psychiatric hold, started on olanzapine and scheduled for a psychiatric facility transfer. The following day, she was noted to have neurological deficits when ambulating. Computed tomography of the brain showed a right frontal …

Developing And Evaluating The Integrated Addiction Recovery Model For The Persons' Engagement And Retention In The Recovery Process Among Clinical Populations From Rwanda, Boniface Harerimana

Electronic Thesis and Dissertation Repository

Background

To date, research that has investigated psychosocial processes and mechanisms, which underpin addiction recovery outcomes are scarce. This study sought to develop and test an integrated addiction recovery model for the recovery process while accounting for an individual’s psychosocial context.

Methods

This predictive study used consecutive sampling strategies to recruit 315 participants from tertiary addiction care settings in Rwanda. Data on the hypothesized model variables and individual’s characteristics were collected with self-reported measures. Structural equation modelling techniques were used to test the model psychometric measures and associations between latent variables.

Results

Baseline data analyses showed a mean age at …

Marijuana And Depression, Pratik Sharma, Ramona Stone

Public Health Sciences Student Work

Purpose: As the country struggles to address an epidemic of alcohol and E-cigarette, a wide-ranging category of natural substance “marijuana” have provoked a new sense of public urgency over the past decade. Notwithstanding the federal ban, selling and use of non-medical marijuana continues to escalate due to state legalization process. The purpose of this cross-sectional study is to determine the relationship between marijuana use and depression.

Methods: The 2013-2014 National Health and Nutrition Examination Survey (CDC) data was used to test the association between marijuana use and depression. This nationally representative weighted sample included N=62,769 adults ages 14 years or …

The Effects Of Involvement In Religious Practices On Recovering Substance Users., Taylor Currier

Honors Theses

This paper reviews empirical studies focused on spirituality and its effects on those in the recovery process from substance abuse. This paper will look at qualitative studies as well as quantitative research to see which form has derived the best results on how spirituality has affected substance abuse recovery. Prolonged recovery is the goal for those that struggle with substance use. Behavior change is an important in sustaining sobriety with those dealing with addiction. It is predicted that those who engage in spiritual growth within their community have a higher likelihood of prolonged recovery than those that do not believe …

The Not So Hidden Dangers Of Vaping, Hannah Lee

BU Well

The use of e-cigarettes and vaping devices has become a widely accepted trend in our society. These devices come with many negative effects that pose harm to one’s health. This article examines the truths about these dangers and the risks associated with vaping.

117— The Effects Of Comorbid Alcohol And Cocaine Use On A Cognitive Maze Task, Shreyya Malik

GREAT Day Posters

In U.S., 1 out of 4 adults reported binge drinking in the past month, a prevalence that increases to over 50% in college populations. Binge drinking is a common precursor for alcohol use disorder, and risk of polydrug use also increases.Cocaine is frequently used in combination with alcohol. Little is known about the history of binge drinking and comorbid cocaine influence on memory. We developed a mouse model of alcohol and cocaine co-use to investigate how comorbidity influences performance on a working memory task. We ran two groups of mice that differed in their history of alcohol use. Group 1 …

118— Environmental Enrichment As A Treatment For Cocaine Relapse, Shreyya Malik

GREAT Day Posters

Cocaine addiction is a problem for millions of people, however we are still lacking an effective treatment. It is characterized by compulsive behaviour which marks difficulties in remaining abstinent, with a high risk of relapse. Here, I focus on the interaction between the post-drug environment and drug-seeking by testing one potential environmental treatment, an enriched environment (EE), to reduce risk of cocaine relapse. This study proposes to investigate neural circuits involved in environmental protection of context-induced relapse. Mice exposed to cocaine will be assessed for preference of a cocaine-associated context using the conditioned place preference (CPP) paradigm. Mice will then …