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Articles 3541 - 3570 of 8047

Full-Text Articles in Medicine and Health Sciences

Functional Limitation And Depressive Symptomatology: Considering Perceived Stigma And Discrimination Within A Stress And Coping Framework, Robyn Lewis Brown May 2017

Functional Limitation And Depressive Symptomatology: Considering Perceived Stigma And Discrimination Within A Stress And Coping Framework, Robyn Lewis Brown

Sociology Faculty Publications

This study examines whether perceived stigma and discrimination moderate the associations between functional limitation, psychosocial coping resources, and depressive symptoms among people with physical disabilities. Using two waves of data from a large community study including a representative sample of persons with physical disabilities (N = 417), an SEM-based moderated mediation analysis was performed. Mediation tests demonstrate that mastery significantly mediates the association between functional limitation and depressive symptoms over the study period. Moderated mediation tests reveal that the linkage between functional limitation and mastery varies as a function of perceived stigma and experiences of major discrimination and day-to-day discrimination, …


The Experience Of Generalized Anxiety Disorder Through The Lens Of Abraham Lincoln: The Effects Of Mental Health Stigma, Daryl Claude Medina May 2017

The Experience Of Generalized Anxiety Disorder Through The Lens Of Abraham Lincoln: The Effects Of Mental Health Stigma, Daryl Claude Medina

Senior Theses

Living with generalized anxiety disorder, also known as GAD, in the United States of America is difficult not only for the individual, but also for the people around him or her. Lifestyle changes have to be made, family dynamics need to be adjusted, and last but not least, all relationships must become flexible. In fact, these major life changes are never fixed and must continually adapt to the needs of the individual with generalized anxiety disorder since it is a lifelong medical condition. As with any other mental illness, dealing with generalized anxiety disorder takes great sacrifice in terms of …


Rct Testing Bystander Effectiveness To Reduce Violence, Ann L. Coker, Heather M. Bush, Patricia G. Cook-Craig, Sarah A. Degue, Emily R. Clear, Candace J. Brancato, Bonnie S. Fisher, Eileen A. Recktenwald May 2017

Rct Testing Bystander Effectiveness To Reduce Violence, Ann L. Coker, Heather M. Bush, Patricia G. Cook-Craig, Sarah A. Degue, Emily R. Clear, Candace J. Brancato, Bonnie S. Fisher, Eileen A. Recktenwald

Obstetrics and Gynecology Faculty Publications

Introduction: Bystander-based programs have shown promise to reduce interpersonal violence at colleges, yet limited rigorous evaluations have addressed bystander intervention effectiveness in high schools. This study evaluated the Green Dot bystander intervention to reduce sexual violence and related forms of interpersonal violence in 26 high schools over 5 years.

Design: A cluster RCT was conducted.

Setting/participants: Kentucky high schools were randomized to intervention or control (wait list) conditions.

Intervention: Green Dot−trained educators conducted schoolwide presentations and recruited student popular opinion leaders to receive bystander training in intervention schools beginning in Year 1.

Main outcome measures: The primary outcome was sexual …


A Guide For Assessing Older Adults’ Needs On Maine Islands, Beatrice Byrne May 2017

A Guide For Assessing Older Adults’ Needs On Maine Islands, Beatrice Byrne

Muskie School Capstones and Dissertations

This template may help Maine island communities identify older adults’ needs and island resources, in order to allow older adults to age in the island communities.

Three interviews with island health leaders, one community conversation with older islanders, and one pilot test provided information about what to include in the template.

The template includes a demographic survey, guides for conducting semi-structured interviews and group conversations with older adults and caregivers, a guide and worksheet for analyzing the data, a guide for assessing community resources, a guide for dissemination, and a list of additional resources.


Analyzing Organizational Commitment And The Effect On Job Turnover In Nurse Residents, Cory D. Church Apr 2017

Analyzing Organizational Commitment And The Effect On Job Turnover In Nurse Residents, Cory D. Church

Nursing Theses and Dissertations

This dissertation is an exploration of psychosocial concepts related to the experiences of a vital health human resource, newly licensed registered nurses. Newly licensed registered nurses are at risk for leaving their first job within the first year due to the difficulty of transitioning to practice. The pressure to gain competence and deliver quality care, all while navigating the workplace environment, can impact their commitment to an organization and the profession. The reader will notice these concepts threaded throughout the dissertation. While these concepts are explored in other nursing workforce populations, the researcher determined a gap in the research on …


A Mixed-Methods Study: Self-Efficacy And Barriers To Participation In Workplace Wellness Programs, Massiel Perez-Calhoon Apr 2017

A Mixed-Methods Study: Self-Efficacy And Barriers To Participation In Workplace Wellness Programs, Massiel Perez-Calhoon

Dissertations

America needs a healthy workforce to sustain the country. The scourge of obesity continues to plague Americans despite government initiatives such as the Affordable Care Act and wellness programs in the workplace to combat this epidemic. However, despite initiatives to make America healthy, barriers continued to impede the nation’s health. Lack of awareness and sensitivity to what motivates individual participants versus group participants built formidable barriers to accessing all workplace employees equitably. The purpose of this study was twofold. First, the intent of this study was to explore the relationship between self-efficacy and the impact on participation and engagement when …


When One Is Sick And Two Need Help: Caregivers’ Perspectives On The Negative Consequences Of Caring, Ilja Ormel, Susan Law, Courtney Abbott, Mark Yaffe, Marc Saint-Cyr, Kerry Kuluski, Debbie Josephson, Ann C. Macaulay Apr 2017

When One Is Sick And Two Need Help: Caregivers’ Perspectives On The Negative Consequences Of Caring, Ilja Ormel, Susan Law, Courtney Abbott, Mark Yaffe, Marc Saint-Cyr, Kerry Kuluski, Debbie Josephson, Ann C. Macaulay

Patient Experience Journal

Informal or family caregivers contribute significantly to individual care, and to the Canadian healthcare system, yet receive limited support from governments, institutions, and healthcare professionals in recognition of their role, or in response to their health and social care needs – often due to the negative consequences of caregiving. Learning about the diversity of others’ experiences can positively influence personal decision-making, reduce feelings of isolation, as well as promote adjustment to a personal situation. For caregivers, however, few resources exist that provide reliable information on others’ experiences. We collected the narratives of caregivers’ experiences of caring for someone with a …


Evaluating Variables Of Patient Experience And The Correlation With Design, Dyutima Jha, Amy Keller Frye, Jennifer Schlimgen Apr 2017

Evaluating Variables Of Patient Experience And The Correlation With Design, Dyutima Jha, Amy Keller Frye, Jennifer Schlimgen

Patient Experience Journal

The objective of this paper was to understand the variables of patient experience by analyzing recent and relevant evidence and to identify design solutions within the hospital environment that positively impact those variables. A systematic review of literature published from 2008-present was conducted to identify variables that contribute to patient experience benefits. Identified variables were documented and categorized into a design, organizational, and outcome variable matrix. Interviews were conducted with professionals from healthcare institutions, architecture firms and organizations committed to improving the patient experience. Data from healthcare facilities, with high patient experience scores, was also examined to derive effective design …


Grounded Theory And The Conundrum Of Literature Review: Framework For Novice Researchers, Mohamed T. El Hussein, Andrea Kennedy, Brent Oliver Apr 2017

Grounded Theory And The Conundrum Of Literature Review: Framework For Novice Researchers, Mohamed T. El Hussein, Andrea Kennedy, Brent Oliver

The Qualitative Report

The issue of the literature review remains a conundrum and a controversy within the discourse on grounded theory methodology. Grounded theory researchers are expected to minimize preconceptions to ensure the concept of interest is grounded in data, yet at the same time are required to evaluate existing literature to support institutional ethics and scientific review of the research proposal. In addressing this dilemma, we espouse that literature review in grounded theory should comprise a multistage nonlinear approach to the literature and introduce a framework for novice grounded theory researchers. This framework offers a reflexive, dynamic and integrative process for conducting …


Improving Lgbt Cultural Competence In Senior Nursing Students, Hallie Orgel Apr 2017

Improving Lgbt Cultural Competence In Senior Nursing Students, Hallie Orgel

Evidence-Based Practice Project Reports

LGBT (lesbian, gay, bisexual, transgender) health care is considered a national priority by The Institute of Medicine (IOM, 2011) and HealthyPeople 2020 (2013). The shortage of LGBT culturally competent health care providers is a top contributor to the oppression and discrimination affecting LGBT health (2013). The purpose of the evidence-based practice (EBP) project was to improve the cultural competence of nursing students by improving their knowledge, attitudes, and skills in working with the LBGT population. A multi-method intervention was provided to seniors in a baccalaureate program. The project took place at a private Midwestern university and utilized a pretest/post-test design. …


High School Student Concussion Recovery Program: Teacher Involvement In Student Academic Transitions To Classroom And To Sports, Brittany Diego Apr 2017

High School Student Concussion Recovery Program: Teacher Involvement In Student Academic Transitions To Classroom And To Sports, Brittany Diego

Scholarly and Creative Works Conference (2015 - 2021)

Many symptoms of concussions can greatly interfere with the cognitive abilities and skills students use in school. Although students may have similar symptoms, they experience concussions differently. Students returning to the classroom from a concussion often have different needs and abilities.

Research shows that a formal, individualized protocol to treat suspected concussions, both academically and physically, is vital to the successful recovery of each student. Much research is available on concussions for professional athletes, specifically related to recovery and returning to their sport. However, there is little research about high school students regarding concussions. Concussion recovery programs for high school …


Rape Crisis Center Professionals' Perception Of Sexual Violence Policy: A Qualitative Analysis, Stephanie Manieri Apr 2017

Rape Crisis Center Professionals' Perception Of Sexual Violence Policy: A Qualitative Analysis, Stephanie Manieri

Scholarly and Creative Works Conference (2015 - 2021)

The purpose of this study is to collect information about the perceptions of rape crisis center professionals regarding the current policies surrounding sexual violence crimes that victimize people over the age of 18. This research aims to gather information about effective and ineffective policies from professionals who are first- responders to sexual assaults.


Exploring The Life Course Perspective In Maternal And Child Health Through Community-Based Participatory Focus Groups: Social Risks Assessment, Abraham Salinas-Miranda, Lindsey M. King, Hamisu M. Salihu, Estrellita "Lo" Berry, Deborah Austin, Susan Nash, Kenneth Scarborough, Evangeline Best, Lillian Cox, Georgette King, Carrie Hepburn, Conchita Burpee, Eugene Richardson, Marlo Ducket, Richard Briscoe, Julie Baldwin Apr 2017

Exploring The Life Course Perspective In Maternal And Child Health Through Community-Based Participatory Focus Groups: Social Risks Assessment, Abraham Salinas-Miranda, Lindsey M. King, Hamisu M. Salihu, Estrellita "Lo" Berry, Deborah Austin, Susan Nash, Kenneth Scarborough, Evangeline Best, Lillian Cox, Georgette King, Carrie Hepburn, Conchita Burpee, Eugene Richardson, Marlo Ducket, Richard Briscoe, Julie Baldwin

Journal of Health Disparities Research and Practice

Little is known about the patterns of risk factors experienced by communities of color and how diverse community contexts shape the health trajectory of women from the early childhood period to the time of their pregnancies. Thus, we conducted a focus group study to identify social risks over the life course that contribute to maternal and child health from the perspective of community members residing in low income urban areas.

Ten community-based participatory focus groups were conducted with residents from selected communities in Tampa, Florida, from September to November 2013. We used the life course perspective to illuminate and explain …


Modeling The Trauma-Antisociality Relationship As Mediated By World Assumptions: Associations With Gender And Drinking Outcomes, Kathryn Fokas Apr 2017

Modeling The Trauma-Antisociality Relationship As Mediated By World Assumptions: Associations With Gender And Drinking Outcomes, Kathryn Fokas

Psychology ETDs

Previous research has established links between traumatic experiences and externalizing pathology including substance use and antisocial behavior, but little is known about potential mechanisms linking these phenomena. This study proposed a novel conceptual model linking these phenomena via the cognitive mechanism of negative world assumptions, or beliefs about the inherent dangerousness and unpredictability of life and others. Given previous mixed findings, this study also sought to explore potential interactions between gender and these phenomena. It was hypothesized that, within a sample of adults seeking alcohol treatment, world assumptions would mediate and gender would moderate the trauma-antisociality association. It also was …


Retention Of Normal Glia Function By An Isoform-Selective Protein Kinase Inhibitor Drug Candidate That Modulates Cytokine Production And Cognitive Outcomes, Zhengqiu Zhou, Adam D. Bachstetter, Claudia B. Späni, Saktimayee M. Roy, D. Martin Watterson, Linda J. Van Eldik Apr 2017

Retention Of Normal Glia Function By An Isoform-Selective Protein Kinase Inhibitor Drug Candidate That Modulates Cytokine Production And Cognitive Outcomes, Zhengqiu Zhou, Adam D. Bachstetter, Claudia B. Späni, Saktimayee M. Roy, D. Martin Watterson, Linda J. Van Eldik

Sanders-Brown Center on Aging Faculty Publications

Background: Brain p38α mitogen-activated protein kinase (MAPK), a potential therapeutic target for cognitive dysfunction based on the neuroinflammation-synaptic dysfunction cycle of pathophysiology progression, offers an innovative pharmacological strategy via inhibiting the same activated target in both glia and neurons, thereby enhancing the possibility for efficacy. The highly selective, brain-penetrant p38αMAPK inhibitor MW150 attenuates cognitive dysfunction in two distinct Alzheimer's disease (AD)-relevant models and avoids the problems encountered with previous mixed-kinase inhibitor drug candidates. Therefore, it is essential that the glial effects of this CNS-active kinase inhibitor be addressed in order to anticipate future use in clinical investigations.

Methods: …


Decreasing Social Isolation Through An Intergenerational Social Engagement Program, Jacqueline Kendona Apr 2017

Decreasing Social Isolation Through An Intergenerational Social Engagement Program, Jacqueline Kendona

Doctor of Occupational Therapy Capstone Projects

Social isolation is the absence of meaningful contact with others. Older adults who perceived themselves as socially isolated are at risk of negative health outcomes. A person’s psychological wellbeing can be improved through engaging in meaningful leisure activities.

The Intergenerational Social Engagement Program, or the ISEP, was developed to connect older adults and high school students to help decrease social isolation in older adults. The ISEP incorporates concepts from the Canadian Model of Occupational Performance and is intended for implementation in senior living communities. The program is to be led by an occupational therapist. Occupational therapy practitioners have an understanding …


An Analysis Of Positive Coping Mechanisms Utilized To Overcome Trauma In Post-Genocidal Rwanda, Danielle Marvin Apr 2017

An Analysis Of Positive Coping Mechanisms Utilized To Overcome Trauma In Post-Genocidal Rwanda, Danielle Marvin

Independent Study Project (ISP) Collection

From April 7th to July 1st of 1994, one million Rwandan people were brutally murdered by their friends and neighbors in the meticulously planned and government-sponsored Genocide against the Tutsi. Survivors witnessed killings and sexual assault, had their lives threatened, lost multiple family members, and hid under dead bodies to evade the killers. To make matters worse, trust within communities and even within families was destroyed as Hutu perpetrators turned against Tutsis they had, days earlier, been inviting to family events. After the genocide, PTSD rates among adults in Rwanda were estimated at 20.5% for men and 30% for women …


Water, Sanitation And Hygiene In Rwamwanja Refugee Settlement, Katelyn Bergl Apr 2017

Water, Sanitation And Hygiene In Rwamwanja Refugee Settlement, Katelyn Bergl

Independent Study Project (ISP) Collection

No abstract provided.


Challenges And Successes Of Adolescent Reproductive Healthcare And Education In Cachoeira, Bahia, Brazil, Elana Margosis Apr 2017

Challenges And Successes Of Adolescent Reproductive Healthcare And Education In Cachoeira, Bahia, Brazil, Elana Margosis

Independent Study Project (ISP) Collection

In this project, I discuss the impact of social, medical, and political factors on the reproductive healthcare of adolescents in Cachoeira, Bahia, Brazil. I collected qualitative data through formal interviews with public health professionals in the Sistema Única de Saúde (SUS), the Brazilian public health system, and through observations of clinic and home visits. Due to ethical concerns, I did not conduct formal interviews with the patients, were not of legal age. I focused on prevention of pregnancy and STI transmission of adolescents as metrics with which to measure sexual health. I gathered information with the intention to understand SUS’ …


Access To Information And Services Regarding Maternal Health And Healthcare Within Tribal Communities Around Udaipur, Rajasthan, Arista Jhanjee Apr 2017

Access To Information And Services Regarding Maternal Health And Healthcare Within Tribal Communities Around Udaipur, Rajasthan, Arista Jhanjee

Independent Study Project (ISP) Collection

The following study seeks to investigate access to antenatal and delivery-related services and information among women residing in rural, tribal communities around Udaipur, Rajasthan, and to analyze determinants that affect such access. More specifically, it seeks to evaluate one determinant in particular: that of association with and use of the services provided by the nonprofit organization Seva Mandir, which works with rural communities throughout southern Rajasthan in order to facilitate the improvement of health and development activities and outcomes. Methods used for the collection of the data upon which the study draws were qualitative: interviews were conducted with 27 women …


Daycare, Decision-Making, And The Determinants Of Health: A Mother-Centric Approach To Understanding Childcare And Child Health In Rural Dharamshala, Arielle Rawlings Apr 2017

Daycare, Decision-Making, And The Determinants Of Health: A Mother-Centric Approach To Understanding Childcare And Child Health In Rural Dharamshala, Arielle Rawlings

Independent Study Project (ISP) Collection

Indian children have long suffered from some of the world’s worst rates of malnutrition. However, there is an evident mismatch between the macro proliferation of India’s intergenerational cycle of malnutrition and the micro ways in which it is often approached, as established views that place blame on mothers for the poor health status of their children have systematically removed blame from underlying structural determinants of health such as government policies, social inequalities, and economic conditions. Taking a mother-centric approach, this study examines the links between childcare practices and maternal decisionmaking in the context of Dharamshala, Kangra District, Himachal Pradesh. Interviews …


Chagas, Enfermedad Olvidada: Una Perspectiva Histórica De La Prevención Y Control Del Chagas En La Provincia De Salta, Argentina (1909 – 2017) \ Chagas, A Forgotten Disease: A Historical Perspective On The Prevention And Control Of Chagas In Salta Province, Argentina (1909 – 2017), Tara Shea Apr 2017

Chagas, Enfermedad Olvidada: Una Perspectiva Histórica De La Prevención Y Control Del Chagas En La Provincia De Salta, Argentina (1909 – 2017) \ Chagas, A Forgotten Disease: A Historical Perspective On The Prevention And Control Of Chagas In Salta Province, Argentina (1909 – 2017), Tara Shea

Independent Study Project (ISP) Collection

El Chagas es una enfermedad vectorial más conocida en zonas rurales de América Latina y en Argentina es endémica en la región noroeste del país (MSAL, 2017). Designada una enfermedad tropical desatendida (Neglected Tropical Disease, NTD) por la OMS, la crónica del Chagas desde su “hallazgo casual” en 1909 siempre se trató de abandono (INP, 2017; MSF, 2012; OMS, 2017; Reyes López, 2009; Stamboulian, 2015; Zabala, 2009). En toda la Argentina se identifican 1.600.000 casos y 7.300.000 personas expuestas al Chagas, dando el país una de las tasas chagásicas más altas del mundo (Bär, 2015; MSAL, 2017).1

El modo de …


El Estudio Del Viejismo En La Ciudad Autónoma De Buenos Aires Desde La Perspectiva De Los Adultos Mayores Con Diferentes Coberturas De Salud \ The Study Of Ageism In The Autonomous City Of Buenos Aires From The Perspective Of Older Adults With Different Health Coverage, Tara Tardino Apr 2017

El Estudio Del Viejismo En La Ciudad Autónoma De Buenos Aires Desde La Perspectiva De Los Adultos Mayores Con Diferentes Coberturas De Salud \ The Study Of Ageism In The Autonomous City Of Buenos Aires From The Perspective Of Older Adults With Different Health Coverage, Tara Tardino

Independent Study Project (ISP) Collection

Argentina is a country with that has a growing population of older adults as the life expectancy continues to increase. Because the population of older people continues to grow, ageism is a topic of concern. Ageism, or discrimination against older people because of their age, can affect one’s mental health, one’s auto-perception of identity and abilities, one’s relationship with his or her doctor, and can contribute to maltreatment and abuse. In this present research I explored how older adults in the Autonomous City of Buenos Aires perceive stereotypes of older people in society, how these stereotypes can lead to discrimination, …


A Bottom-Up Approach To Effectively Implementing A Good Samaritan Policy At Bryant University, Jessica Fleet Apr 2017

A Bottom-Up Approach To Effectively Implementing A Good Samaritan Policy At Bryant University, Jessica Fleet

Honors Projects in History and Social Sciences

The rising numbers of substance consumption on college campuses are becoming a public concern for higher educational institutions across the United States. The thesis studies the relationship between state laws and private higher education institution laws in regards to substance abuse. Examining state laws and private universities Medical Amnesty and Good Samaritan laws were used to determine what would effectively replace Bryant University’s current Substance Abuse Policy. The current policy lacks an educational element along with stressing the word of mouth ideology that students are protected when in need of drug or alcohol assistance in a medical situation. This is …


The Jagori Rural Charitable Trust Model: Menstrual Education Of Women And Adolescent Girls In The Villages Of Rural Dharamsala, Madelon Morford Apr 2017

The Jagori Rural Charitable Trust Model: Menstrual Education Of Women And Adolescent Girls In The Villages Of Rural Dharamsala, Madelon Morford

Independent Study Project (ISP) Collection

Reproductive rights and education of women in rural communities is of lesser importance in India’s patriarchal society. Reproductive health is a conversation that is rarely discussed, and the health status of women is of little priority behind that of men and children’s health. Education about the health and hygiene of menstruation allows for women and adolescent girls to play a role in their own health maintenance, as well as normalizes the discussion of menstruation and reproductive health. Studying Jagori Rural Charitable Trust’s efforts to disseminate knowledge about reproductive health, with specific focus on menstruation, allows for an understanding of the …


A Review Of 57 Zone: A Social Media Network For Tb Consultation And Communication In Kunming, China, India Medaris Apr 2017

A Review Of 57 Zone: A Social Media Network For Tb Consultation And Communication In Kunming, China, India Medaris

Independent Study Project (ISP) Collection

Yunnan, a predominantly agricultural province in southwest China, is a province with a high rate of both tuberculosis (TB) and multi-drug resistant tuberculosis (MDR TB), with nearly 25,000 cases of pulmonary TB reported each year. Former TB/MDR TB patients in Yunnan, with the support of Family Health International 360 NGO (FHI) are trying to combat this problem. They have created a social media network for TB consultation and communication, 57 Zone, where TB patients can talk about their medication, adverse drug effects, and nutrition and psychosocial concerns. The goal of this study was the look at what aspects of the …


A Medical Student Foray Into The Depths Of Public Health: An Exploratory Investigation Toward A Community Dashboard Characterizing The Experiences Of Frailty In Order To Guide Improvement, An Harmanli, Danielle Fahoome, Burton Masem, Ellen Massey, Beverly Lunsford, Joanne Lynn, Elizabeth Cobbs Apr 2017

A Medical Student Foray Into The Depths Of Public Health: An Exploratory Investigation Toward A Community Dashboard Characterizing The Experiences Of Frailty In Order To Guide Improvement, An Harmanli, Danielle Fahoome, Burton Masem, Ellen Massey, Beverly Lunsford, Joanne Lynn, Elizabeth Cobbs

GW Research Days 2016 - 2020

While it is known that there are many shortcomings in the care of the elderly, their rate and impact on the community and the elderly themselves is not well understood. In exploring the possibilities for using existing data and available informants, a dashboard could be created that would enable a geographic community to understand the experience of living with disabilities in old age, to prioritize problems, and to test improvements.

The methods included a literature review to understand what and how easily information could be accessed, gathered, and presented. In regards to literature on data collection, CMS claims data, MDS, …


Csf Protein Changes Associated With Hippocampal Sclerosis Risk Gene Variants Highlight Impact Of Grn/Pgrn, David W. Fardo, Yuriko Katsumata, John S. K. Kauwe, Yuetiva Deming, Oscar Harari, Carlos Cruchaga, Alzheimer’S Disease Neuroimaging Initiative, Peter T. Nelson Apr 2017

Csf Protein Changes Associated With Hippocampal Sclerosis Risk Gene Variants Highlight Impact Of Grn/Pgrn, David W. Fardo, Yuriko Katsumata, John S. K. Kauwe, Yuetiva Deming, Oscar Harari, Carlos Cruchaga, Alzheimer’S Disease Neuroimaging Initiative, Peter T. Nelson

Sanders-Brown Center on Aging Faculty Publications

Objective—Hippocampal sclerosis of aging (HS-Aging) is a common cause of dementia in older adults. We tested the variability in cerebrospinal fluid (CSF) proteins associated with previously identified HS-Aging risk single nucleotide polymorphisms (SNPs).

Methods—Alzheimer’s Disease Neuroimaging Initiative cohort (ADNI; n=237) data, combining both multiplexed proteomics CSF and genotype data, were used to assess the association between CSF analytes and risk SNPs in four genes (SNPs): GRN (rs5848), TMEM106B (rs1990622), ABCC9 (rs704180), and KCNMB2 (rs9637454). For controls, non-HS-Aging SNPs in APOE (rs429358/rs7412) and MAPT (rs8070723) were also analyzed against Aβ1-42 and total tau CSF analytes.

Results—The GRN risk …


Being Transgender And Seeking Healthcare In The World’S Most Liberal City, Nicole Sharpe Apr 2017

Being Transgender And Seeking Healthcare In The World’S Most Liberal City, Nicole Sharpe

Independent Study Project (ISP) Collection

The right to the highest form of healthcare is one of the most essential rights a person should have. It should be accessible to all human beings, and it appears this is not the case when it comes from the transgender population in the Netherlands and the U.S. In addition to transitional health care needs like hormonal treatment and surgery, transgender people require the same variety of general health care needs as many other groups of individuals. When obstacles create stigma within health care providing facilities, transgender individuals may be less inclined or discouraged to seek the care they need. …


The Disappearance Of Nyoman And Ketut, Laura Michelle Garvie Apr 2017

The Disappearance Of Nyoman And Ketut, Laura Michelle Garvie

Independent Study Project (ISP) Collection

No abstract provided.