Medicine and Health Sciences Commons^™

A Computational Model For Recovery From Brain Injury, Wayne Wakeland

Systems Science Friday Noon Seminar Series

A computational simulation model calculates recovery trajectories following traumatic brain injury (TBI). Prior publications include a multi-scale framework for studying concussion and a systems-level causal loop diagram (CLD) and discussion of feedback processes. The scope of the computational model goes beyond concussion to include all severities of TBI. A set of first order ordinary differential equations and their associated parameters determines recovery trajectories. While highly speculative, the model serves to demonstrate the potential utility of computational models in this context. Much more research will be needed to create a properly supported research model that could be used for clinical trial …

The Tail Wagging The Dog: Positive Attitude Towards Livestock Guarding Dogs Do Not Mitigate Pastoralists’ Opinions Of Wolves Or Grizzly Bears, Daniel Kinka, Julie K. Young

United States Department of Agriculture Wildlife Services: Staff Publications

While the re-establishment of grizzly bears (Ursus arctos) and wolves (Canis lupus) in the American West marks a success for conservation, it has been contentious among pastoralists. Coincidentally, livestock guarding dogs (LGDs; Canis familiaris) have been widely adopted by producers of domestic sheep (Ovis aries) in the United States to mitigate livestock depredation by wild carnivores. We surveyed pastoralists to measure how experience with and attitudes towards LGDs related to attitudes towards livestock predators, and found positive responses regarding LGDs and negative responses regarding wolves and grizzly bears. The more respondents agreed that LGDs reduce the need for lethal management …

Mathematics Saves Lives: Models And Signals Enabling Medicine And Biology, Raina Robeva

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Evaluation Of Age- And Risk-Based Mass Drug Administration Policies To Control Soil-Transmitted Helminths: A Mathematical Modeling Study Of Ghana, Mugdha Thakur

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Transient Dynamics Of Infection Transmission In An Intensive Care Unit, Christopher Short, Matthew S. Mietchen, Eric T. Lofgren

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Oscillation In Mathematical Epidemiology, Meredith Greer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Classification Of Coronary Artery Disease In Non-Diabetic Patients Using Artificial Neural Networks, Demond Handley

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Multidisciplinary Education And Research In Biomathematics For Solving Global Challenges, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Automation Of Karl Fischer Titration For Animal Pharmaceutical Product Testing At Elanco Animal Health, Elizabeth L. Grubbs

Annual Student Research Poster Session

Ever wonder what doing research looks like in the context of working in industry? This summer I had the opportunity to work at Elanco Animal Health, the world’s third largest animal pharmaceutical company (and growing!) I worked in the Quality Control laboratories where products are tested before they are sent out the door. I did research to automate a process that checks for the water content of various animal health products. The water content of these products is important for many reasons including expiration dates and FDA requirements. The process that I automated is called Karl Fischer titration and is …

Ethnobotany And Dai Medicine: Herbal Roots, Jasper Tsai

Independent Study Project (ISP) Collection

Xishuangbanna is home to one of the most biologically and culturally diverse regions in China. Dai medicine from the Dai people has been recognized by China as one of the four major ethnic minority medicines. With over 2,500 years of practice, Dai medicine utilizes the herbs found in the diverse region mixed with principles and theories from Buddhism. There have been over 500 unique herbs used in Dai medicine, each with different properties and functions. As Xishuangbanna continues to develop as a city and expand its rubber and banana plantations, it has large impacts on the environment, living standard, education, …

Leaving Ligand Effects On Reactivity And Solubility Of Monofunctional Platinum(Ii) Anticancer Complexes, Heidi Linn Hruska Millay

Masters Theses & Specialist Projects

Monofunctional platinum(II) complexes, such as phenanthriplatin and pyriplatin, have notably different characteristics from the bifunctional anticancer complexes, such as cisplatin and oxaliplatin, which have detrimental toxicities and resistance associated with them. The unique properties of the monofunctional complexes may be exploited to target cancer cells without producing the toxic side effects associated with the current FDA-approved platinum-based anticancer drugs. To advance the understanding of these monofunctional platinum(II) complexes, this study replaced the chloride leaving ligand with an acetate group, which should increase solubility and alter the rate of reactivity with key amino acid and nucleotide targets. Phenanthriplatin and pyriplatin compounds …

Interaction Of A Platinum Triamine Complex Having A Seven-Membered Chelate Ring With N-Acetyl-Lmethionine And Guanosine 5'-Monophosphate, Jae Ko

Masters Theses & Specialist Projects

In the 1960s, Rosenberg and his colleagues confirmed the anti-cancer activity of cisplatin. Although cisplatin was capable of killing testicular cancer cells there were also serious side effects. It was necessary to find alternate ways of overcoming side effects, and soon many researchers have discovered novel platinum compounds that show similar reactivity. Recently, replacing one chloride group to a heterocyclic amine group showed significant cytotoxicity with a different binding activity than cisplatin. Previously in our lab, [Pt(Me5dien)(NO3)]+ and [Pt(Et2dien)Cl]+ have been synthesized and reacted with NAcetyl- L-methionine (N-AcMet) and Guanosine 5’-monophosphate (5’-GMP) showed unusual reactivity. Unlike most previously studied platinum …

Differences In Duration Of Untreated Psychosis For Racial And Ethnic Minority Groups With First-Episode Psychosis: An Updated Systematic Review And Meta-Analysis., Nicole Schoer, Chen Wei Huang, Kelly K. Anderson

Epidemiology and Biostatistics Publications

PURPOSE: Ethnic minority groups with early psychosis may have longer treatment delays, potentially leading to poorer outcomes. We updated a previous systematic review of the literature on racial and ethnic differences in duration of untreated psychosis (DUP) among people with first-episode psychosis.

RESULTS: Six of 17 studies described significant differences across aggregated racial groups; however, the pooled estimates did not show differences across groups. Additional data from this update allowed for disaggregated analyses, finding that Black-African groups have a shorter DUP, whereas Black-Caribbean groups have longer DUP, relative to White groups.

CONCLUSIONS: These findings highlight the importance of in-depth research …

The Changing Role Of Rodenticides And Their Alternatives In The Management Of Commensal Rodents, Gary Witmer

United States Department of Agriculture Wildlife Services: Staff Publications

Rodents cause substantial damage and losses of foodstuffs around the world. They also transmit many diseases to humans and livestock. While various methods are used to reduce damage caused by rodents, rodenticides remain an important tool in the toolbox. However, like all tools, rodenticides have advantages and disadvantages. Several considerations are shaping the future of rodenticide use, including manufacturing and registration costs, concern about toxicity levels and nontarget animal hazards, potential hazards to children, reduced effectiveness of some formulations, and humaneness to the targeted rodents. Many of these disadvantages apply to anticoagulant rodenticides, and their use is being more restricted …

Synthesis Of Bis(Imino)Pyridine Iron(Ii) Complexes And Development Of Bis(Imino)Pyridine Iron(Ii) Catalyzed Carbene Transfer Reactions, Ban Wang

Masters Theses & Specialist Projects

Metal catalysis of symmetric and asymmetric carbene transfer reactions has been widely applied in natural product synthesis and material science over years. Metal carbene can be easily generated from the extrusion of nitrogen under the catalysis of metal complexes to further undergo various organic reactions, O/N/C-H insertions, cycloadditions, and ylide formations. Currently, the dominant effective catalysts for carbene reactions are built with expensive precious metal, for example, rhodium, ruthenium, palladium, gold. Notably, the effective reactivity and enantioselectivity of the dirhodium(II) catalysts are researched and established over the decades. However, the use of precious metal catalysts is the major source of …

Socioemotional Selectivity And Psychological Health In Amyotrophic Lateral Sclerosis Patients And Caregivers: A Longitudinal, Dyadic Analysis, Suzanne C. Segerstrom, Edward J. Kasarskis, David W. Fardo, Philip M. Westgate

Psychology Faculty Publications

Objective: Socioemotional selectivity theory predicts that as the end of life approaches, goals and resources that provide immediate, hedonic reward become more important than those that provide delayed rewards. This study tested whether these goal domains differentially affected psychological health in the context of marital dyads in which one partner had been diagnosed with amyotrophic lateral sclerosis (ALS), a life-limiting disease.

Design: ALS patients (N = 102) being treated in three multidisciplinary clinics and their spouses (N = 100) reported their loneliness, financial worry and psychological health every 3 months for up to 18 months.

Main …

South Dakota State University : Research Fall 2019, South Dakota State University

State of Discovery South Dakota State University's Research Magazine

[Page] 2 Curcumin formulation on its way to health product market
[Page] 4 Flexibility key to forging research partnership with Kodo Kids
[Page] 6 Researcher examines hope among children in Flint, Michigan
[Page] 7 Plant pathologist battles stem canker
[Page] 8 Removing ‘Typhoid Marys’ restores health of Custer bighorn sheep herd
[Page] 10 Breeder, food scientist help improve quality of oats, increase local production
[Page] 13 SDSU, community leaders explore new ways to drive research, partnerships
[Page] 14 SDSU, community leaders explore new ways to drive research, partnerships
[Page] 16 Engineering builds business connections through Research Park
[Page] 17 Research …

Tracking Canada Geese Near Airports: Using Spatial Data To Better Inform Management, Ryan Askren, Brett E. Dorak, Heath M. Hagy, Michael W. Eichholz, Brian E. Washburn, Michael P. Ward

United States Department of Agriculture Wildlife Services: Staff Publications

The adaptation of birds to urban environments has created direct hazards to air transportation with the potential for catastrophic incidents. Bird–aircraft collisions involving Canada geese (Branta canadensis; goose) pose greater risks to aircraft than many bird species due to their size and flocking behavior. However, information on factors driving movements of geese near airports and within aircraft arrival/departure areas for application to management are limited. To address this need, we deployed 31 neck collar-mounted global positioning system transmitters on Canada geese near Midway International Airport in Chicago, Illinois, USA during November 2015 to February 2016. We used the movement data …

Effectiveness Of Snap And A24-Automated Traps And Broadcast Anticoagulant Bait In Suppressing Commensal Rodents In Hawaii, Aaron B. Shiels, Tyler Bogardus, Jobriath Rohrer, Kapua Kawelo

United States Department of Agriculture Wildlife Services: Staff Publications

Commensal rodents (invasive rats, Rattus spp.; house mice, Mus musculus) are well established globally. They threaten human health by disease transfer and impact economies by causing agricultural damage. On island landscapes, they are frequent predators of native species and affect biodiversity. To provide managers with better information regarding methods to suppress commensal rodent populations in remote island forests, in 2016 we evaluated the effectiveness of continuous rat trapping using snap-traps, Goodnature® A24 self-resetting rat traps, and a 1-time (2-application) hand-broadcast of anticoagulant rodenticide bait pellets (Diphacinone-50) applied at 13.8 kg/ha per application in a 5-ha forest on Oahu, Hawaii, USA. …

Application Strategy For An Anthraquinonebased Repellent And The Protection Of Soybeans From Canada Goose Depredation, Scott J. Werner, Matthew Gottlob, Charles D. Dieter, Joshua D. Stafford

United States Department of Agriculture Wildlife Services: Staff Publications

Agricultural crops can sustain extensive damage caused by Canada geese (Branta canadensis) when these crops are planted near wetlands or brood-rearing sites. From 2000 to 2015, South Dakota Game, Fish and Parks spent >$5.6 million to manage damages caused by Canada geese to agricultural crops (primarily soybeans) in South Dakota, USA. For the purpose of developing a repellent application strategy for nonlethal goose damage management, we comparatively evaluated the width of anthraquinone applications (i.e., 9.4 L Flight Control® Plus goose repellent/ha [active ingredient: 50% 9,10-anthraquinone] at 0–36 m versus 0–73 m perpendicular to the edge of wetlands in 2014), the …

A Review Of Rat Lungworm Infection And Recent Data On Its Definitive Hosts In Hawaii, Chris Niebuhr, Susan I. Jarvi, Shane R. Siers

United States Department of Agriculture Wildlife Services: Staff Publications

Rat lungworm (Angiostrongylus cantonensis) is a zoonotic nematode that causes rat lungworm disease (angiostrongyliasis), a potentially debilitating form of meningitis, in humans worldwide. The definitive hosts for rat lungworm are primarily members of the genus Rattus, with gastropods as intermediate hosts. This parasite has emerged as an important public health concern in the United States, especially in Hawaii, where the number of human cases has increased in the last decade. Here we discuss the current knowledge of the rat lungworm, including information on the life cycle and host species, as well as updates on known infection levels. Three species of …

Estimating Waterbird Abundance On Catfish Aquaculture Ponds Using An Unmanned Aerial System, Paul C. Burr, Sathishkumar Samiappan, Lee A. Hathcock, Robert J. Moorhead, Brian S. Dorr

United States Department of Agriculture Wildlife Services: Staff Publications

In this study, we examined the use of an unmanned aerial system (UAS) to monitor fish-eating birds on catfish (Ictalurus spp.) aquaculture facilities in Mississippi, USA. We tested 2 automated computer algorithms to identify bird species using mosaicked imagery taken from a UAS platform. One algorithm identified birds based on color alone (color segmentation), and the other algorithm used shape recognition (template matching), and the results of each algorithm were compared directly to manual counts of the same imagery. We captured digital imagery of great egrets (Ardea alba), great blue herons (A. herodias), and doublecrested cormorants (Phalacrocorax auritus) on aquaculture …

Smartbfa: A Passive Crowdsourcing System For Point-To-Point Barrier-Free Access, Mohammed Nazir Kamaldin, Susan Kee, Songwei Kong, Chengkai Lee, Huiguang Liang, Alisha Saini, Hwee-Pink Tan, Hwee Xian Tan

Research Collection School Of Computing and Information Systems

At the Bloomberg Live `Sooner Than You Think' forum [1] held in Singapore in 2018, nearly 75% of delegates picked inclusiveness to be the key measure of success for a smart city. An inclusive smart city is a citizen-centered approach that extends the experiences provided by smart city solutions to all citizens, including seniors and persons with disabilities (PwDs).Despite existing regulations on barrier-free accessibility for buildings and public infrastructure, pedestrian infrastructure is generally still inaccessible to PwDs in many parts of the world. In this paper, we present SmartBFA (Smart Mobility and Accessibility for Barrier Free Access) - a publicly-funded …

Fall 2019

Scientia

Education Taking Flight; The Vincentian Question and the Chemistry Teacher; Science Goes Global; Minister of Hope: Neurosurgeon and cancer researcher Alfredo Quinones-Hinojosa, MD, believes hope is more powerful than fear; What's New: The college introduced four new programs and tracks in its offerings for the 2019-20 academic year; Lab Notes; A Teacher Who Really Counts: Golden Apple Recipient Candice Cortese (CSH MA '10) Reflects on her Love of Teaching Math; One Smart Cookie: Chemistry Student Lucienna Wolf Says, "If You Really Apply Yourself, the Teachers Are More Than Happy to Help You."

An Analysis Of The Rajasthan Public Health System’S Response To The 2019 Dengue Insurgence, Luke Bryan

Independent Study Project (ISP) Collection

Dengue virus is in a pandemic status and is a major public health issue in the modern world. The mosquito-borne disease is largely prevalent in Asia and specifically India, where more than half of the states are considered to have complete presence of the dengue virus. The intricate infrastructure of the Indian public health system looks for dengue cases at all levels and reports to the integrated disease surveillance programme (IDSP).

Analyses of the IDSP and trends of dengue cases was done in response to dengue outbreaks throughout the state. Geographic information system (GIS) maps were created to evaluate a …

Follow-Up Decision Support Tool For Public Healthcare: A Design Research Perspective, Shah J. Miah, Najmul Hasan, John Gammack

All Works

© 2019, Korean Society of Medical Informatics. All rights reserved. Objectives: Mobile health (m-Health) technologies may provide an appropriate follow-up support service for patient groups with post-treatment conditions. While previous studies have introduced m-Health methods for patient care, a smart system that may provide follow-up communication and decision support remains limited to the management of a few specific types of diseases. This paper introduces an m-Health solution in the current climate of increased demand for electronic information exchange. Methods: Adopting a novel design science research approach, we developed an innovative solution model for post-treatment follow-up decision support interaction for use …

Mental Health And Gun Violence: A Link Held By Misperception, Neil Morte, Kelly L. Sullivan

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

No abstract provided.

An Animal-Assisted Intervention Study In The Nursing Home: Lessons Learned, Lonneke G. J. A. Schuurmans, Inge Noback, Jos M. G. A. Schols, Marie-Jose Enders-Slegers

People and Animals: The International Journal of Research and Practice

AAI studies in the nursing home pose a specific set of challenges. In this article the practical and ethical issues encountered during a Dutch psychogeriatric nursing home AAI study are addressed with the aim of sharing our experiences for future researchers as well as AAI practitioners in general.

In our study we compared three groups of clients with dementia who participated in group sessions of either visiting dog teams, visiting FurReal Friend robot animals, or visiting students (control group) and monitored the effect on social interaction and neuropsychiatric symptoms through video analysis and questionnaires. We encountered the following four categories …

Sure 2019 Undergraduate Science Conference Booklet, Sure Network

Group Reports

The Second Annual Science Undergraduate Research Experience (SURE) Conferences (SURE 2019) took place on 27th September 2019 in Institute of Technology, Carlow, Technological University Dublin and Institute of Technology, Sligo. The simultaneous conferences had a total of 23 oral presentations and 67 poster presentations, and were attended by over 450 students, academic staff, professional body and industry representatives.

The aims of the conference were to:

• Provide current students with an opportunity to gain an understanding of the work which has been undertaken by recent graduates, and the career opportunities that exist for graduates in Scientific disciplines.
• Provide recent graduates with …

Metformin Blunts Muscle Hypertrophy In Response To Progressive Resistance Exercise Training In Older Adults: A Randomized, Double‐Blind, Placebo‐Controlled, Multicenter Trial: The Masters Trial, R. Grace Walton, Cory M. Dungan, Douglas E. Long, S. Craig Tuggle, Kate Kosmac, Bailey D. Peck, Heather M. Bush, Alejandro G. Villasante Tezanos, Gerald Mcgwin, Samuel T. Windham, Fernando Ovalle, Marcas M. Bamman, Philip A. Kern, Charlotte A. Peterson

Center for Muscle Biology Faculty Publications

Progressive resistance exercise training (PRT) is the most effective known intervention for combating aging skeletal muscle atrophy. However, the hypertrophic response to PRT is variable, and this may be due to muscle inflammation susceptibility. Metformin reduces inflammation, so we hypothesized that metformin would augment the muscle response to PRT in healthy women and men aged 65 and older. In a randomized, double-blind trial, participants received 1,700 mg/day metformin (N = 46) or placebo (N = 48) throughout the study, and all subjects performed 14 weeks of supervised PRT. Although responses to PRT varied, placebo gained more lean body …