Interprofessional Peer Teaching: Assistive Device Training And Medications Impacting Safe Ambulation, Niamh M. Tunney, Melissa Chesson, Gina J. Ryan

Internet Journal of Allied Health Sciences and Practice

ABSTRACT

Purpose: An interprofessional peer teaching activity was designed and implemented to provide students with an opportunity to practice interprofessional education collaborative (IPEC) competencies while improving student knowledge of assistive devices for gait and medications impacting safe ambulation. Method: During the activity, second year physical therapy students instructed third year pharmacy students in the accurate fit and counseling for use of canes, crutches, and walkers. Pharmacy students then demonstrated these skills and were checked off on their ability to accurately fit and instruct consumers on basic gait patterns. The pharmacy students in turn educated the physical therapy students about medications …

A Case Of Intertrochanteric Fracture, Sahil Munjal

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Alcohol Induced Psychotic Disorder With Depression Presenting During Covid19 Lockdown, Dr. Sopan T, Dr Kishor M

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Spina Bifida Occulta With Tethered Cord Syndrome, Dr. Shivangi G, Dr. M.D. Ravi

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Squamous Cell Carcinoma, Dr. Pranav Prabhu, Dr. Gurgi Mukthinath

Digital Journal of Clinical Medicine

No abstract provided.

The Effects Of Scheduling Acetaminophen And Methocarbamol Administration On Postoperative Opioid Use And Related Side Effects Among Cardiac Surgery Patients, Whitney Jamison

DNP Projects

The Effects of Scheduled Acetaminophen and Methocarbamol Administration on Postoperative Opioid Use and Related Side Effects Among Cardiac Surgery Patients

ABSTRACT

Purpose

Opioid therapy is commonly prescribed to combat surgical pain in hospitals across the United States and is associated with many negative side effects including dependence and nausea. The purpose of this study was to retrospectively examine the effects of scheduling acetaminophen and methocarbamol administration postoperatively throughout the cardiac surgery patients’ hospital stay. Through retrospective chart reviews, the aims of postoperative opioid use, postoperative opioid use according to hospital length of stay, antiemetic use, and opioid prescription at discharge …

Using Electrolyte Repletion Guidelines To Improve The Rate Of Oral Potassium And Magnesium Delivery, Joshua Riley, Alan Kubey, Md

Phase 1

Introduction: Evidence-based guidelines for electrolyte replacement that safely encourage oral (PO) and/or intravenous (IV) dosing more successfully attain goal levels than standard care. However, the Thomas Jefferson University Hospital (TJUH) electrolyte replacement guidelines (JG 11-1296), approved in 2002 and last updated in 2008, provide guidance for IV repletion not PO. Between 5/2017-11/2017, TJUH dosed potassium and magnesium in a 2.30 and 4.24 IV:PO ratio, respectively. If 50% of doses were given PO, we anticipate ~$800,000 annual TJUH savings.

Methods: We created a multidisciplinary team and completed a literature review to inform the creation of updated TJUH guidelines for …

Antioxidant And Antimicrobial Activities Of Crude Extracts Of Actinomycetes From Soils, Khaing Zar Wai

Chulalongkorn University Theses and Dissertations (Chula ETD)

A total of 17 actinomycetes isolated from soil collected from Nong Khai, Nakhon Ratchasima, Khon Kaen, Phichit, Chachoengsao and Udonthani Province, were evaluated on antimicrobial and antioxidant activities. They were identified as Streptomyces (16 strains) and Micromonospora (1 strain) based on their phenotypic and chemotaxonomic characteristics including 16S rRNA gene sequences analysis. Strain JA03 showed 98.95% similarity of 16S rRNA gene sequence to S. puniciscabiei DSM 41929T. Strain JA03 was found to be the novel species of genus Streptomyces based on whole genome average nucleotide identity (ANI). All these strains were evaluated on antimicrobial and antioxidant activities. Based on agar …

Effect Of Jorunnamycin A On Cancer Stem Cells Of Human Lung Cancer H460 Cells, Somruethai Sumkhemthong

Chulalongkorn University Theses and Dissertations (Chula ETD)

It has been recognized that cancer stem-like cells (CSCs) in tumor tissue crucially contribute to therapeutic failure, resulting in a high mortality rate in lung cancer patients. Due to their stem-like features of self-renewal and tumor formation, CSCs can lead to drug resistance and tumor recurrence. Herein, the suppressive effect of jorunnamycin A, a bistetrahydroisoquinolinequinone isolated from Thai blue sponge Xestospongia sp., on cancer spheroid initiation and self-renewal in the CSCs of human lung cancer cells is revealed. The depletion of stemness transcription factors, including Nanog, Oct-4, and Sox2 in the lung CSC-enriched population treated with jorunnamycin A (0.5 µM), …

Aloe Vera And Health Outcomes: An Umbrella Review Of Systematic Reviews And Meta-Analyses, Saranrat Sadoyu

Chulalongkorn University Theses and Dissertations (Chula ETD)

This umbrella review aims to summarize and assess the effects of Aloe vera on health outcomes. Methods: Only systematic reviews and meta-analyses of clinical trials that investigated the effects of Aloe vera on health outcomes were eligible. PubMed, Scopus, Embase, Cochrane database of systematic reviews, CINAHL, and AMED were searched from inception to October 2019. Two independent reviewers extracted data, assessed the methodological quality, and rated the credibility of evidence according to established criteria into convincing, highly suggestive, suggestive, weak, and not significant. Results: Ten articles reporting 71 unique outcomes of Aloe vera were included. Of these, 47 (67%) were …

Production Of Recombinant Protein Ltb-Ctla4 By Transient Plant-Based Expression Using Geminiviral Vector, Sutita Yiemchavee

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cancer is one of the leading global causes of death. In 2018, WHO estimated that 9.6 million patients died from cancer, with 18.1 million new cases emerged. In recent years, immunotherapy is considered as a treatment improving cancer-related immune function by manipulating the immune checkpoints in the immune system. Cytotoxic-T-lymphocyte antigen 4 (CTLA-4) is a immune checkpoint transmembrane protein. The expression of CTLA-4 on the surface of activated T-cell could downregulate the production and proliferation of cytotoxic T-lymphocyte cells (CTLs). CTLs are the host-defended immune cells that could retard the growth of cancer cells by recognizing the tumor-associated antigens expressed …

Formulation Development Of Extended And Immediate Release Tablets Using Extrusion-Based 3d Printing Technology, Yee Mon Than

Chulalongkorn University Theses and Dissertations (Chula ETD)

Fused deposition modelling (FDM) based 3D printing technology for oral solid dosage form has shown promising results in the fabrication of individualized tablets compared to conventional method. However, the main concern of this technique is the quality of drug loaded filament including mechanical properties such as flexibility, stiffness and brittleness. To cope with these problems, filaments were produced via hot melt extrusion (HME) by screening and characterizing a series of pharmaceutical mixtures (6 types of polymers and 5 types of disintegrants) and processing parameters for specifying the design space in Design of Experiment (DoE). Therefore, the purposes of the present …

Introducing A Model And A Framework To Unify The Pharmaceutical Quality System Enablers Quality Risk Management & Knowledge Management, Martin J. Lipa, Kevin O'Donnell, Anne Greene

Articles

An organization that effectively manages knowledge should be able to recognize and proactively apply new learnings to better anticipate risks. This is particularly important in the manufacture of medicinal products. Since the publication of ICH Q10 in 2010, Quality Risk Management (QRM) and Knowledge Management (KM) have been positioned as co-enablers to the Pharmaceutical Quality System. The authors of this paper present a Knowledge Management process model to foster greater practical understanding of the practice of knowledge management. This model when joined with the familiar ICH Q9 process model for QRM, should enable a company to better manage their knowledge …

Multicellular Spheroids Of A549 And A549-Irfp As An In Vitro Model Of Lung Cancer, Xinyu Pei

University of the Pacific Theses and Dissertations

Lung cancer is the second most common cancer in both men and women around the world, and 85% of it is non-small cell lung cancer (NSCLC). It is estimated that in 2020, there will be 228,820 cases of lung cancer and 135,720 deaths from lung (American Cancer Society, 2020). The prognosis of lung cancer is poor (

Traditionally, the most commonly used in vitro method for screening therapeutic drugs is monolayer cell cultures, which are reproducible, convenient and of low cost. However, monolayer cell culture models are unable to reproduce many properties of in vivo solid tumors such as the …

Tubular Adenoma Of Breast, Diksha Dadlani

Digital Journal of Clinical Medicine

No abstract provided.

Kikuchi-Fujimoto Disease, Rohan Karkra

Digital Journal of Clinical Medicine

No abstract provided.

Macular And Optic Disc Drusenoid Deposits With Hemifield Defects In A Patient With Iga Nephropathy: New Findings, Dr. Prabhakar S K

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Megaloblastic Anemia With Suspected Gilbert Syndrome, Nair A, Prasad R, Dr. Ravikumar S, Dr. Prasanna Kumar

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Recurrent Pregnancy Loss Due To Bicornuate Uterus, Chandran S

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Right Lower Lobe Lung Abscess With Stage Iii Empyema, Dey Sauparna, Dr. Ravi M D

Digital Journal of Clinical Medicine

No abstract provided.

Uterine Prolapse, Nimisha Sinha, Sakshi Anurika, Dr. Anu Prerana

Digital Journal of Clinical Medicine

No abstract provided.

Ataxia Telangiectasia- A Case Report, Pooja Pallavi, Dr. Rajani H.S

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Sjogren’S Syndrome With Leucocytoclastic Vasculitis With Hypokalemic Periodic Paralysis, Dr. Pranay Penmetsa, Dr. Subramanian R

Digital Journal of Clinical Medicine

No abstract provided.

“Hunting” A Case Of External Ophthalmoplegia: Tolosa-Hunt Syndrome, Dr Vaishnavi S.G, Dr Shasthara P

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Tenofovir Induced Osteopenia, Dr Kruthi M, Dr Rajendra Prasad S

Digital Journal of Clinical Medicine

No abstract provided.

Implementation Of A Pediatric Pharmacy Education Program At A Community Regional Medical Center., Chelsea L Ferguson Pharmd, Sarah Ferrell Pharmd, Karen Kovey Pharmd, Joanna Young, Sara Trovinger

Parkview Pharmacy Department

OBJECTIVES: This study aimed to implement a web-based pediatric education program designed for pharmacists who participate in neonatal and pediatric order verification at a community-based health system and to evaluate the success through measuring outcomes related to both comfort and competence of pharmacists in pediatric and neonatal pharmacotherapy.

METHODS: This prospective quality improvement study assessed changes in confidence and competence from before to after education. Eight educational modules were designed to provide education based on the needs of this institution. All pharmacists who participate in neonatal and pediatric order verification were eligible for inclusion throughout the health system. Time in …

An Evaluation Of The Medical Management Received In The Institutional Setting During Cardiac Arrest At A Community Hospital, Danielle Carr, Jillian Coons Pharmd, Bcps, Jamie Gaul Pharmd, Bcps, Sarah Ferrell Pharmd, Abby L. Todt Pharmd, Bcps

Parkview Pharmacy Department

2020 ASHP Midyear Clinical Meeting / Virtual Meeting / Poster # SP-501

Objective: To evaluate the medical management patients receive in the institutional setting during cardiac arrest compared to the 2019 American Heart Association (AHA) advanced cardiac life support (ACLS) treatment algorithms

Appropriateness Of Intravenous Acetaminophen Use In The Emergency Departments Across A Multi-Hospital Community Health System, Allison Clemens Pharmd, Sarah Meeks Pharmd, Bryan Statz Pharmd

Parkview Pharmacy Department

2020 ASHP Midyear Clinical Meeting

The objective of this study was to evaluate adherence to institutional restriction criteria for intravenous acetaminophen use in the emergency departments within a community hospital system.

Evaluation Of Beta-Lactam Allergy Classification And Carbapenem Use In Patients Admitted To The Medical-Surgical Floors Of A Large, Community Hospital, Zachary Brown Pharmd, Dylan Walker, Trent Towne Pharmd, Bcps

Parkview Pharmacy Department

Background and Objective

Background • CDC reports half of patients admitted to the hospital received at least 1 dose of antibiotics from 2006-2012 • Approximately 32 million people in the United States have a documented allergy to a beta-lactam (BL) antibiotic • Approximately 10% of all US patients report having an allergic reaction to a BL in their lifetime • Fewer than 1% has a true IgE (immunoglobulin E) mediated allergy to a BL • Over 80% of those patients with an IgE-mediated allergy lose sensitivity after 10 years • Penicillin-skin testing cost: ~$220 • Per the CDC, carbapenem use …

Evaluation Of A Pharmacy Managed Vancomycin Dosing Protocol For Critically Ill Adult Patients Requiring Continuous Renal Replacement Therapy (Crrt) At A Community Hospital, Ally Fulton, Aubrey Mills Pharmd, Abby L. Todt Pharmd, Bcps, Sarah Ferrell Pharmd, Jamie Gaul Pharmd, Bcps

Parkview Pharmacy Department

2020 ASHP Midyear Clinical Meeting / Virtual Meeting/ Poster

Objective: The purpose of this medication use evaluation (MUE) was to evaluate a pharmacy managed vancomycin dosing protocol for patients on CRRT patients in a community hospital.