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Articles 72391 - 72420 of 77117

Full-Text Articles in Medicine and Health Sciences

Pre-Verbal Trauma, Dissociation And The Healing Process, Dorothy Dreier Scotten Jan 2003

Pre-Verbal Trauma, Dissociation And The Healing Process, Dorothy Dreier Scotten

Educational Studies Dissertations

This qualitative research study examines some of the ways in which the healing process takes place in adults who have experienced dissociation, and who have most likely been psychologically traumatized before full language development. The impact of early trauma on human cognitive, socio-emotional, and spiritual development are explored within the context of participant narratives in order to develop an understanding of what may be helpful in developing effective teaching strategies for clinical and teacher education. In-depth interviews were conducted with four adult persons who had been diagnosed with Dissociative Identity Disorder. All had histories of infant psychological trauma and all …

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Bidirectional Cavopulmonary Shunt For Cyanotic Heart Disease: Surgical Experience From A Developing Country, G. Khan, S. S. Ali, Saulat H. Fatimi Jan 2003

Bidirectional Cavopulmonary Shunt For Cyanotic Heart Disease: Surgical Experience From A Developing Country, G. Khan, S. S. Ali, Saulat H. Fatimi

Section of Cardiothoracic Surgery

Objective: The importance of bidirectional cavopulmonary anastomosis for palliation of complex cyanotic con-genital heart disease is widely recognized. This study was conducted to highlight our surgical experience withthis procedure in a developing country.
Methods: A retrospective study was conducted using medical records at the Aga Khan University Hospital,Karachi, Pakistan. Clinical findings at presentation, anatomical defects seen on transthoracic echocardiography,pre-operative McGoon index, cardiopulmonary bypass time, use of cardioplegia,post-procedure oxygen satura-tions and complications were evaluated.
Results: A total of 8 patients underwent bidirectional cavopulmonary anastomosis. There were 6 males (75%)and 2 females (25%). Ages and weights atoperation averaged 5.7 ± 3.7 …

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The Prevalence Of Silent Kidney Stones: An Ultrasonographic Screening Study, Buchholz Niels-Peter, Farhat Abbas, R Khan, Jamsheer J. Talati, M Afzal, I Rizvi Jan 2003

The Prevalence Of Silent Kidney Stones: An Ultrasonographic Screening Study, Buchholz Niels-Peter, Farhat Abbas, R Khan, Jamsheer J. Talati, M Afzal, I Rizvi

Section of Urology

Objective: Silent and not yet discovered stones of the upper urinary tract are potentially dangerous, since in due course they may cause infection, obstruction and renal damage. The aim of this study was to determine the prevalence of such silent kidney stones in a representative Pakistani population of Karachi.
Subjects and Methods: We studied 201 consecutive subjects at our hospital who underwent additional kidney screening whilst undergoing abdominal ultrasound. All these subjects did not have a history or symptoms of urolithiasis.
Results: We found silent kidney stones in 3% of subjects. All stone bearers were males. Most stones were in …

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Optimization Of Low Pre-Operative Hemoglobin Reduces Transfusion Requirement In Patients Undergoing Transurethral Resection Of Prostate, Hammad Ather, Nuzhat Faruqui, F. Abid Jan 2003

Optimization Of Low Pre-Operative Hemoglobin Reduces Transfusion Requirement In Patients Undergoing Transurethral Resection Of Prostate, Hammad Ather, Nuzhat Faruqui, F. Abid

Section of Urology

Objective: To identify factors that influence peri-operative hemorrhage in view of reducing the need for transfusions in patients undergoing trans uretheral resection of prostate (TURP).
Methods: All patients undergoing TURP between January 1997 and December 1999 were identified using lCD 9CM coding and indexing system. Overall 430 patients were identified, however, 384 charts were included and reviewed for demographics, pre and intra-operative data and post-operative morbidity. Patients were divided into two groups on the basis of presence of significant hemorrhage.
Results: Overall 384 patients were analyzed. Nineteen patients had hemorrhage - group I whereas 365had no significant hemorrhage …

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Quality Improvement: Physician Providers, And The Women Health Connection Program, In The Provision Of Breast And Cervical Cancer Screening Services In Nevada., Salome K. Kapella Jan 2003

Quality Improvement: Physician Providers, And The Women Health Connection Program, In The Provision Of Breast And Cervical Cancer Screening Services In Nevada., Salome K. Kapella

UNLV Theses, Dissertations, Professional Papers, and Capstones

Quality Improvement is one of the best solutions to the performance of healthcare services. The purpose of this study is to identify areas that need to be improved in relationship between physician providers and the Women Health Connection Program (WHC) in the provision of breast and cervical cancer screening services in Nevada. An assessment of how physicians view the program, their cooperation with the WHC program, an analysis of areas for improvement and the value of services to WHC clients have been discussed in order to improve the quality of breast and cervical cancer in the state. Comparisons have been …

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Use Of Heart Rate Reserve And Rating Of Perceived Exertion To Prescribe Exercise Intensity In Diabetic Autonomic Neueropathy, Sheri R. Colberg, David P. Swain, Aaron I. Vinik Jan 2003

Use Of Heart Rate Reserve And Rating Of Perceived Exertion To Prescribe Exercise Intensity In Diabetic Autonomic Neueropathy, Sheri R. Colberg, David P. Swain, Aaron I. Vinik

Human Movement Studies & Special Education Faculty Publications

Objective- Individuals with diabetic autonomic neuropathy (DAN) exhibit an increased resting heart rate but depressed maximal heart rate. Thus, the purpose of this study was to examine the validity of using either percent of heart rate reserve (HRR) or a rating of perceived exertion (RPE) scale to prescribe exercise intensity in diabetic individuals both with and without DAN.

Research Design and Methods-The subjects consisted of 23 individuals with type 2 diabetes, ages 45-75 years, with (DAN; n=13) or without (No DAN; n=10) clinical signs of DAN, as assessed by heart rate variability using the expiration-to-inspiration ratio of the …

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Are Our People Health Conscious? Results Of A Patients Survey In Karachi, Pakistan, Waris Qidwai, D Saleheen, S Saleem, M Andrades, Iqbal Azam Jan 2003

Are Our People Health Conscious? Results Of A Patients Survey In Karachi, Pakistan, Waris Qidwai, D Saleheen, S Saleem, M Andrades, Iqbal Azam

Department of Family Medicine

BACKGROUND: Life style is known to influence health and may be responsible for certain diseases. There is a need to document the life style on health among the Pakistani population.
METHODS: The study was conducted on patients visiting the Family Practice Center, the Aga Khan University, Karachi. A questionnaire was used to collect information on the demographic profile, and the life style on health. The ethical requirements for conducting the study were met.
RESULTS: 393 patients were surveyed. The majority were young married men, in either private or government service. Preference for consumption of fats/oils, sweets, spicy foods, …

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A Comparison Between Conventional And Holistic Exercise Interventions On Physiological Function In The Elderly, Gavin R. Mccormack Jan 2003

A Comparison Between Conventional And Holistic Exercise Interventions On Physiological Function In The Elderly, Gavin R. Mccormack

Theses: Doctorates and Masters

Aging is characterised by a decline in physiological function. The rate of this decline can depend on certain lifestyle factors, genetics, and the environment. Although life expectancy is slowly increasing, there is a need to reduce the time spent in debilitated, and non-independent states by elderly individuals. Preventive measures need to be implemented to reduce dependency and improve the quality of life for elderly individuals. One such preventive and remedial measure is the use of exercise and physical activity. Because limited exercise prescription exists for the elderly population, there is a need to determine the effectiveness of exercise interventions that …

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Clarifying The Lower Incidence Of Birth Defects In The Midwest Of Western Australia : A Study Using Capture Re-Capture Methodology, Donna Baker Jan 2003

Clarifying The Lower Incidence Of Birth Defects In The Midwest Of Western Australia : A Study Using Capture Re-Capture Methodology, Donna Baker

Theses: Doctorates and Masters

In April 2000 the Western Australian Birth Defects Registry held its 20th Anniversary Scientific Symposium to signify the first 20 years of the Birth Defects Registry in Western Australia. At the Symposium, significant trends and occurrences in birth defects within Western Australia over the past 20 years were addressed. One factor highlighted in the Registry's 1980-1999 report was that birth defects were reported less frequently in rural regions compared with metropolitan areas. Data collected from the metropolitan area is considered by the Birth Defects Registry to be the most accurate. Therefore, incidence rates of birth defects in this area arc …

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Fall Risk Assessment : A Prospective Investigation Of Nurses' Clinical Judgement And Risk Assessment Tools In Predicting Patient Falls In An Acute Care Setting, Helen Myers Jan 2003

Fall Risk Assessment : A Prospective Investigation Of Nurses' Clinical Judgement And Risk Assessment Tools In Predicting Patient Falls In An Acute Care Setting, Helen Myers

Theses: Doctorates and Masters

Falls are a significant problem in acute care, hospital settings, and can have serious consequences, especially for older patients. Fall prevention has therefore been recognised as an important area for research and intervention. In order to target interventions and use resources effectively, a major strategy of many fall prevention programmes has been the development and/or use of risk assessment tools to identify patients who are at high risk of falling. Although many tools have been developed, few have been rigorously tested, and there is currently no evidence to support the clinical utility of fall risk assessment tools. There is a …

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All In Due Time: Perspectives On Childbirth From Deaf Parents, Rsa Region V Project Jan 2003

All In Due Time: Perspectives On Childbirth From Deaf Parents, Rsa Region V Project

Course Materials

Six Deaf couples discuss their experiences of giving birth. The stories they share represent a variety of factors and complications that occurred before, during, and after the births of their children.

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Increased Risk Of Cervical Canal Infections With Intracervical Foley Catheter, S Siddiqui, Nf Zuberi, Afia Zafar, Rn Qureshi Jan 2003

Increased Risk Of Cervical Canal Infections With Intracervical Foley Catheter, S Siddiqui, Nf Zuberi, Afia Zafar, Rn Qureshi

Department of Obstetrics & Gynaecology

OBJECTIVE: To evaluate the effect of intracervical Foley catheter insertion, for the induction of labor, on cervical canal infection.
DESIGN: A prospective interventional study with paired analysis.
PLACE AND DURATION OF STUDY: The study was conducted in the department of Obstetrics and Gynecology at the Aga Khan University, Karachi, between June 1 and August 31, 2002.
SUBJECTS AND METHODS: In 45 women undergoing cervical ripening with intracervical Foley catheter for the induction of labour at term, cervical swabs were taken for culture and sensitivity before its insertion and again after its spontaneous expulsion or removal.
RESULTS: Intracervical …

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The Role Of Meat, Poultry, And Fish Consumption In The Occurrence Of Rheumatoid And Other Forms Of Arthritis, Asnake Hailu Jan 2003

The Role Of Meat, Poultry, And Fish Consumption In The Occurrence Of Rheumatoid And Other Forms Of Arthritis, Asnake Hailu

Loma Linda University Electronic Theses, Dissertations & Projects

Rheumatoid arthritis and other forms of arthritis or rheumatism are now the leading cause of disability in the United States. The etiology and pathogenesis are less understood and available treatment options are not always satisfactory. This dissertation measures the prevalence and cumulative incidence of rheumatoid arthritis and other forms of arthritis or rheumatism, and examines any associations with current and lifetime consumption of meat, poultry, and fish (meat) using the Adventist Health Study and the Adventist Mortality Study databases. From these databases, it was possible to reconstruct a prospective cohort, obtain self-reported information on demographic characteristics, arthritis, rheumatoid arthritis, other …

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Communication Skills Of Family Physicians In A Doctor-Patient Consultation, Waris Qidwai, Si Karim, Fm. Irfan Jan 2003

Communication Skills Of Family Physicians In A Doctor-Patient Consultation, Waris Qidwai, Si Karim, Fm. Irfan

Department of Family Medicine

No abstract provided.

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Physical Exercise As A Key Health Determinant Among Patients, Waris Qidwai, Danish Saleheen, Sadia Saleem, Marie Andrades, Iqbal Azam Jan 2003

Physical Exercise As A Key Health Determinant Among Patients, Waris Qidwai, Danish Saleheen, Sadia Saleem, Marie Andrades, Iqbal Azam

Department of Family Medicine

No abstract provided.

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Patient Complaints Among Emergency Room Patients At A Teaching Hospital In Karachi, Waris Qidwai, Muhammad Baqir, Syed Sohail Ali, Semi Ayub Jan 2003

Patient Complaints Among Emergency Room Patients At A Teaching Hospital In Karachi, Waris Qidwai, Muhammad Baqir, Syed Sohail Ali, Semi Ayub

Department of Family Medicine

OBJECTIVES: To study the chief presenting complaints among patients presenting to the Emergency Medical services.
SETTING: This study was conducted at the Emergency Room of Aga Khan University Hospital, Karachi during March and April, 2003.
METHODS: A survey was carried out by the study investigators. This survey included patients who were not very sick and were selected at random. Demographic profiles of the respondents were noted. EPI-info and SPSS computer software programs were used for analysis of the results.
RESULTS: One hundred patients were surveyed. The majority was relatively young, married men and women, well educated and …

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Perceptions On Bioethics Among Patients Presenting To Family Physicians At A Teaching Hospital In Karachi, Waris Qidwai, Hafeez Qureshi, Syed Sohail Ali, Mahboob Alam, Syed Lgbal Azam Jan 2003

Perceptions On Bioethics Among Patients Presenting To Family Physicians At A Teaching Hospital In Karachi, Waris Qidwai, Hafeez Qureshi, Syed Sohail Ali, Mahboob Alam, Syed Lgbal Azam

Department of Family Medicine

Objective: To study the perceptions on bioethics among patients presenting to family physicians at a teaching hospital in Karachi, Pakistan Study design: Questionnaire based cross sectional survey
Settings: The study was carried out at the family practice center, the Aga Khan University Hospital, Karachi Main outcome measures: Perceptions on the broad principles of bioethics
Results: Majority of the respondents were young and well educated and better placed socioeconomically. Respondents reported the moral duties of a physician and their reaction in the event of the death of a close relative due to a doctor`s negligence. The majority agreed …

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Paternalistic Model Of Medical Practice, Waris Qidwai Jan 2003

Paternalistic Model Of Medical Practice, Waris Qidwai

Department of Family Medicine

No abstract provided.

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Use Of Services Of Spiritual Healers Among Patients Presenting To Family Physicians At A Teaching Hospital In Karachi, Pakistan, Waris Qidwai Jan 2003

Use Of Services Of Spiritual Healers Among Patients Presenting To Family Physicians At A Teaching Hospital In Karachi, Pakistan, Waris Qidwai

Department of Family Medicine

Objective: To study the use of the services of spiritual healers, among patients visiting the family physicians, at a teaching hospital in, Karachi. Design: Cross-sectional survey
Place and Duration of Study: Family practice center, the Aga Khan University, Karachi, from February to June, 2001
Subjects and Methods: A total of 387 patients were surveyed. A questionnaire was developed and administered to collect information on the use of the services of spiritual healers among the respondents.
Results: Most of the respondents were young, well educated and better placed socio-economically. The use of the services of spiritual healers …

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Implications For The Practice Of A Patient Expectation And Satisfaction Survey, At A Teaching Hospital In Karachi, Pakistan, Waris Qidwai, R. H. Dhanani, F. M. Khan Jan 2003

Implications For The Practice Of A Patient Expectation And Satisfaction Survey, At A Teaching Hospital In Karachi, Pakistan, Waris Qidwai, R. H. Dhanani, F. M. Khan

Department of Family Medicine

Objective: To study the expectations and satisfaction of patients visiting Family Practice Clinics, at the Aga Khan University Hospital, in Karachi, Pakistan. Methodology: A cross sectional survey of 316 patients was carried out. A questionnaire, based on the study objectives was developed and administered. The participating patient signed a consent form, after assurance of confidentiality was provided. Data on the demographic profile of the patients was collected.
Results: The mean age was 33.81 years, with 105 (33.2%) women, and 211 (66.8%) men. The majority were married, with education above intermediate level and were in private or government service or were …

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Prevalence And Perceptions About Consanguineous Marriages Among Patients Presenting To Family Physicians, In 2001 At A Teaching Hospital In Karachi, Pakistan, Waris Qidwai, Iqbal Azam, Faisal M Khan Jan 2003

Prevalence And Perceptions About Consanguineous Marriages Among Patients Presenting To Family Physicians, In 2001 At A Teaching Hospital In Karachi, Pakistan, Waris Qidwai, Iqbal Azam, Faisal M Khan

Department of Family Medicine

Aim: Consanguineous marriages are common in Pakistan despite their declining popularity in the developed world. In the present study, a questionnaire based survey was used to record the attitudes and perceptions of consanguineous marriages among the sample population.
Methods: A questionnaire was developed to collect information on the acceptability of, and perceptions about, consanguineous marriages among patients presenting to family physicians, at the Family Practice Center of the Aga Khan University Hospital in Karachi, Pakistan. Demographic data was collected as part of the questionnaire. Each participating patient signed a consent form after assurance of confidentiality was provided.
Results …

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Animal Anti-Apoptotic Genes Ameliorate The Loss Of Turgor In Water-Stressed Transgenic Tobacco, Tala Awada, D. D. Dunigan, M. B. Dickman Jan 2003

Animal Anti-Apoptotic Genes Ameliorate The Loss Of Turgor In Water-Stressed Transgenic Tobacco, Tala Awada, D. D. Dunigan, M. B. Dickman

Nebraska Center for Virology: Faculty Publications

Nicotiana tabacum L. ‘Glurk’ plants were transformed with antiapoptotic animal genes [chicken Bcl-xl; nematode CED-9; chicken Bcl-xl(GA) a mutant of Bcl-xl; and a 3’ non-coding region of human Bcl-2, referred to as 161-1]. Our objectives were to determine whether plant transformation with anti-apoptotic genes ameliorates drought tolerance in tobacco plants by subjecting the plants to a dry-down period. The non-transformed Glurk and the transgenic Glurk harboring G115, which expresses β-glucuronidase, served as controls. Transformation of tobacco plants with animal anti-apoptotic genes significantly impacted the rates of photosynthesis (A) and stomatal conductance (gs), but not to the same extent …

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Identification Of Novel Domains Within Sox-2 And Sox-11 Involved In Autoinhibition Of Dna Binding And Partnership Specificity, Matthew S. Wiebe, Tamara K. Nowling, Angie Rizzino Jan 2003

Identification Of Novel Domains Within Sox-2 And Sox-11 Involved In Autoinhibition Of Dna Binding And Partnership Specificity, Matthew S. Wiebe, Tamara K. Nowling, Angie Rizzino

Nebraska Center for Virology: Faculty Publications

Sox transcription factors play key regulatory roles throughout development, binding DNA through a consensus (A/T)(A/T)CAA(A/T)G sequence. Although many different Sox proteins bind to this se-quence, it has been observed that gene regulatory elements are commonly responsive to only a small subset of the entire family, implying that regulatory mechanisms exist to permit selective DNA bind-ing and/or transactivation by Sox family members. To identify and explore the mechanisms modu-lating gene activation by Sox proteins further, we compared the function of Sox-2 and Sox-11. This led to the discovery that Sox proteins are regulated differentially at multiple levels, including trans-activation, protein partnerships …

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Saru, A Sara Homolog, Is Repressed By Sart And Regulates Virulence Genes In Staphylococcus Aureus, Adhar C. Manna, Ambrose L. Cheung Jan 2003

Saru, A Sara Homolog, Is Repressed By Sart And Regulates Virulence Genes In Staphylococcus Aureus, Adhar C. Manna, Ambrose L. Cheung

Dartmouth Scholarship

In searching the Staphylococcus aureus genome, we previously identified sarT, a homolog of sarA, which encodes a repressor for alpha-hemolysin synthesis. Adjacent but transcribed divergently to sarT is sarU, which encodes a 247-residue polypeptide, almost twice the length of SarA. Sequence alignment disclosed that SarU, like SarS, which is another SarA homolog, could be envisioned as a molecule with two halves, with each half being homologous to SarA. SarU, as a member of the SarA family proteins, disclosed conservation of basic residues within the helix-turn-helix motif and within the beta hairpin loop, two putative DNA binding domains within this protein …

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Prenatal Chromosomal Diversification Of Leukemia In Monozygotic Twins, Helena Kempski, Karen A. Mensa- Bonsu, Lyndal Kearney, G. Reza Jalali, Ian Hann, Mohammad Khurshid, Mel Greaves Jan 2003

Prenatal Chromosomal Diversification Of Leukemia In Monozygotic Twins, Helena Kempski, Karen A. Mensa- Bonsu, Lyndal Kearney, G. Reza Jalali, Ian Hann, Mohammad Khurshid, Mel Greaves

Section of Haematology/Oncology

Previous studies on concordant acute lymphoblastic leukemia (ALL) in identical twins have identified the leukemia as monoclonal with MLL or ETV6-RUNX1 gene fusion as early or initiating events in utero. In the latter case, postnatal latency is associated with secondary genetic events such as ETV6 deletion. We describe here a pair of infant twins with concordant acute monoblastic leukemia (AML). They are a unique pair in that their leukemia blasts display extensive intraclonal chromosomal diversity. Comparison of the leukemic cells between the two twins by karyotype and fluorescence in situ hybridization identifies a common or shared stem line …

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Hyalgan® Has A Dose-Dependent Differential Effect On Macrophage Proliferation And Cell Death, Kyle M. Sheehan, Lindsey B. Delott, Susan M. Day, David H. Deheer Jan 2003

Hyalgan® Has A Dose-Dependent Differential Effect On Macrophage Proliferation And Cell Death, Kyle M. Sheehan, Lindsey B. Delott, Susan M. Day, David H. Deheer

University Faculty Publications and Creative Works

The intra-articular injection of high molecular weight hyaluronic acid (HA) has been reported to be an effective treatment for pain of osteoarthritis of the knee. However, the mechanism by which HA exerts its effect is unknown. To explore HA's influence on the growth of U937 human macrophages, cells were incubated for 168 h with three concentrations, 1, 0.1 and 0.01 mg/mL, of Hyalgan®, a high molecular weight HA preparation. At 24-h increments, the cells were examined for proliferation, cell cycle distribution as well as the number of apoptotic and dead cells. Exposing macrophages to 1 mg/mL Hyalgan® significantly reduced the …

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Antipyretic, Parasitologic, And Immunologic Effects Of Combining Sulfadoxine/Pyrimethamine With Chloroquine Or Paracetamol For Treating Uncomplicated Plasmodium Falciparum Malaria, E. Hugosson, D. Tarimo, M. Troye-Blomberg, S.M. Montgomery, Zul Premji, A. Bjorkman Jan 2003

Antipyretic, Parasitologic, And Immunologic Effects Of Combining Sulfadoxine/Pyrimethamine With Chloroquine Or Paracetamol For Treating Uncomplicated Plasmodium Falciparum Malaria, E. Hugosson, D. Tarimo, M. Troye-Blomberg, S.M. Montgomery, Zul Premji, A. Bjorkman

Pathology, East Africa

Sulfadoxine/pyrimethamine (SP) is increasingly used against malaria in sub-Saharan Africa because of chloroquine resistance. However, chloroquine may have a beneficial antipyretic effect. We therefore compared the combination of SP plus chloroquine, chloroquine alone, SP alone, and SP plus paracetamol in the treatment of uncomplicated Plasmodium falciparum malaria in 175 Tanzanian children (1-4 years old) in a randomized trial. Outcome variables were axillary temperatures every six hours, daily parasitemias, and serum levels of IgG antibodies to P. falciparum. Lower mean temperatures (6-48 hours) were achieved with SP plus chloroquine or paracetamol than with SP alone (P < 0.001) or chloroquine alone (P < 0.05). All three SP-treated groups showed high and similar parasite reduction (0-48 hours), whereas treatment with chloroquine alone was much less effective. Levels of IgG antibodies to P. falciparum increased significantly (P < 0.001) and similarly in the four treatment groups between days 0, 2. and 3. Thus, the addition of chloroquine or paracetamol to SP improved the clinical outcome, but did not affect the parasitologic response or antibody production.

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Role Of Neuropoietic Cytokines In Development And Progression Of Diabetic Polyneuropathy: From Glucose Metabolism To Neurodegeneration, Dusanka S. Skundric, Robert P. Lisak Jan 2003

Role Of Neuropoietic Cytokines In Development And Progression Of Diabetic Polyneuropathy: From Glucose Metabolism To Neurodegeneration, Dusanka S. Skundric, Robert P. Lisak

Neurology Faculty Publications

Diabetic neuropathy develops as a result of hyperglycemia- induced local metabolic and microvascular changes in both type I and type II diabetes mellitus. Diabetic neuropathy shows slower impulse conduction, axonal degeneration, and impaired regeneration. Diabetic neuropathy affects peripheral, central, and visceral sensorimotor and motor nerves, causing improper locomotor and visceral organ dysfunctions. The pathogenesis of diabetic neuropathy is complex and involves multiple pathways. Lack of success in preventing neuropathy, even with successful treatment of hyperglycemia, suggests the presence of early mediators between hyperglycemia-induced metabolic and enzymatic changes and functional and structural properties of Schwann cells (SCs) and axons. It is …

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Prostate Cancer: Some Clinical And Scientific Dilemmas., Paul D. Abel, El-Nasir Lalani Jan 2003

Prostate Cancer: Some Clinical And Scientific Dilemmas., Paul D. Abel, El-Nasir Lalani

Department of Pathology and Laboratory Medicine

No abstract provided.

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Use Of Intravenous Anti-D In Patients With Refractory And Relapsed Immune Thrombocytopenic Purpura, R. Sajid, Salman Adil, Z. Fadoo, S. Sabir, Mohammad Khurshid Jan 2003

Use Of Intravenous Anti-D In Patients With Refractory And Relapsed Immune Thrombocytopenic Purpura, R. Sajid, Salman Adil, Z. Fadoo, S. Sabir, Mohammad Khurshid

Department of Pathology and Laboratory Medicine

Objective: To determine the response to IV anti-D and its comparison with splenectomy as second line therapy in refractory and relapsed cases of ITP, in the Aga Khan University Hospital, Karachi.
Methods: A total of 23 patients with chronic ITP were treated with either anti-D or splenectomy as second line treatment. The patients were assessed for time to achieve a response to second line treatment, duration ofresponse and adverse events.
Results: There were 12 patients in the anti-D group and 11 in the splenectomy group. The mean platelet count at presentation was 9,000/cumm. The mean age was 8.9 …

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