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Articles 43981 - 44010 of 45148

Full-Text Articles in Medicine and Health Sciences

In Situ Hybridization For The Detection And Localization Of Swine Chlamydia Trachomatis, C. Chae, D.-S. Cheon, D. Kwon, O. Kim, B. Kim, J. Suh, D. G. Rogers, K. D. E. Everett, A. A. Anderson Jan 1999

In Situ Hybridization For The Detection And Localization Of Swine Chlamydia Trachomatis, C. Chae, D.-S. Cheon, D. Kwon, O. Kim, B. Kim, J. Suh, D. G. Rogers, K. D. E. Everett, A. A. Anderson

School of Veterinary and Biomedical Sciences: Faculty Publications

Gnotobiotic piglets were inoculated intralaryngeally with swine Chlamydia trachomatis strain R33 or orally with swine C. trachmatis strain R27. Archived formalin-fixed, paraffin-embedded tissues from piglets euthanatized 4–7 days postinoculation were examined by in situ hybridization for C. trachomatis nucleic acid using a nonradioactive digoxigenin-labeled DNA probes that targeted specific ribosomal RNA or omp1 mRNA molecules of the swine C. trachomatis strains. Positive hybridization signals were detected in bronchial epithelial cells, bronchiolar epithelial cells, pneumocytes, alveolar and interstitial macrophages, and jejunal and ileal enterocytes. Chlamydia-infected cells had a strong signal that was confined to the intracytoplasmic inclusions. Positive hybridization signals were …


Potential Associations Among Genetic Markers In The Serotonergic System And The Antisocial Alcoholism Subtype, E. M. Hill, S. F. Stoltenberg, M. Burmeister, M. Closser, R. A. Zucker Jan 1999

Potential Associations Among Genetic Markers In The Serotonergic System And The Antisocial Alcoholism Subtype, E. M. Hill, S. F. Stoltenberg, M. Burmeister, M. Closser, R. A. Zucker

Department of Psychology: Faculty Publications

Alcoholism is transmitted in families. The complexity and heterogeneity of this disorder has made it difficult to identify specific genetic correlates. One design with the potential to do so is the family-based association study, in which the frequencies of genetic polymorphisms are compared between affected and nonaffected members. Reduced central serotonin neurotransmission is associated with features of an antisocial subtype of alcoholism, although a primary deficit has not been traced to a particular component. Genetic markers related to the serotonergic system have been identified, located, and cloned. If associations can be discovered, the development process for pharmacotherapy could be facilitated. …


The Effect Of Fish Oil On Liver And Plasma Mda And Antioxidant Status Of Rats, Nuriye Mete, Birgül Işik, Levent Erdi̇nç, Fuat Gürkan Jan 1999

The Effect Of Fish Oil On Liver And Plasma Mda And Antioxidant Status Of Rats, Nuriye Mete, Birgül Işik, Levent Erdi̇nç, Fuat Gürkan

Turkish Journal of Medical Sciences

The question how fish oil (FO) and soybean oil (SO) change the state of antioxidant and the lipid peroxidation in liver and plasma of rats and the protective role of vitamin E were investigated. Six-week-old forty male Sprague-Dawley rats were divided into five groups. One of the groups fed a control diet, another one fed SO, while the other three groups fed FO diet at the level of 10% Vitamin E supplementation was maintained to three different levels 3, 50, 150 IU/per kg diet in the FO diets and 3 IU vitamin E per kg of the SO diet. At …


Quantification Of Total Collagen In Rabbit Tendonby The Sirius Red Method, Dilek Taşkiran, Emin Taşkiran, Hüseyin Yercan, Fatma Z. Kutay Jan 1999

Quantification Of Total Collagen In Rabbit Tendonby The Sirius Red Method, Dilek Taşkiran, Emin Taşkiran, Hüseyin Yercan, Fatma Z. Kutay

Turkish Journal of Medical Sciences

No abstract provided.


Genitourinary Abnormalities In Children With Urinary Tract Infections, Ayşe Balat, L. Leighton Hill Jan 1999

Genitourinary Abnormalities In Children With Urinary Tract Infections, Ayşe Balat, L. Leighton Hill

Turkish Journal of Medical Sciences

Urinary-tract infections (UTI) are common infectious diseases in childhood. The presence of UTI may be an indicator of a serious genitourinary (GU) abnormality that requires medical intervention. We retrospectively reviewed the charts of children discharged with a diagnosis of UTI from the Texas Children's Hospital, Houston, Texas, between July 1, 1991 and June 30, 1994. The purpose of the study was to determine how many patients had underlying GU abnormalities, the specific type of abnormality, and the microorganism causing the UTI. During the 3-year period, there were 48,382 discharges from the hospital, and 1,221 (2.5%) of those discharges were patients …


Effect Of Exercise On Blood Antioxidant Status And Erythrocyte Lipid Peroxidation: Role Of Dietary Supplementation Of Vitamin E, Mustafa Kelle, Hüda Di̇ken, Abdurrahman Şermet, Mukadder Atmaca, Cemi̇l Tümer Jan 1999

Effect Of Exercise On Blood Antioxidant Status And Erythrocyte Lipid Peroxidation: Role Of Dietary Supplementation Of Vitamin E, Mustafa Kelle, Hüda Di̇ken, Abdurrahman Şermet, Mukadder Atmaca, Cemi̇l Tümer

Turkish Journal of Medical Sciences

We tested the effects of moderate physical exercise on the blood antioxidant capacity and erythrocyte lipid peroxidation in 21 Wistar albino rats. Erythrocyte superoxide dismutase (SOD) activity increased significantly (p


Administration Of Granulocyte Colonystimulating Factor (G-Csf) In Experimentallyinfected Rats, Ömer Cevi̇t, Ruhi̇ye Cevi̇t, Gökhan Köylüoğlu, Di̇lara İçağasioğlu, Asim Gülteki̇n, Fatoş Tanzer Jan 1999

Administration Of Granulocyte Colonystimulating Factor (G-Csf) In Experimentallyinfected Rats, Ömer Cevi̇t, Ruhi̇ye Cevi̇t, Gökhan Köylüoğlu, Di̇lara İçağasioğlu, Asim Gülteki̇n, Fatoş Tanzer

Turkish Journal of Medical Sciences

We investigated the effect of antibiotic or G-CSF plus antibiotic therapy given to E. coli septic rats. In our study, 80 rats were inoculated transperitoneally with 1 ml of a solution containing 10 7 colony forming units per milliliter of E. coli. Rats were divided into four treatment groups before being inoculaded with E. coli in a random fashion. Therapy was then started with cefotaxime (150 mg/kg intraperitonelally) and either Granulocyte-Colony Stimulation Factor (G-CSF; 30 µg/kg intarperitoneally) or placebo 24 hours after inoculation of E. coli for 3 consective days. Group A 1 , sepsis-antibiotics group, had a mortality rate …


A Patient With Three Simultaneously Occurring Malignancies, Bahar Kiliçarslan, Gülay Özbi̇li̇m, Gökbay Elpek, Şeyda Karaveli̇, Mi̇ne Üner Jan 1999

A Patient With Three Simultaneously Occurring Malignancies, Bahar Kiliçarslan, Gülay Özbi̇li̇m, Gökbay Elpek, Şeyda Karaveli̇, Mi̇ne Üner

Turkish Journal of Medical Sciences

No abstract provided.


The Evaluation Of Microanastomoses In Rats Withcolor Doppler Ultrasonography, Bahri̇ Üstünsöz, İbrahi̇m Somuncu, Mahmut Kömürcü, Mustafa Başşbozkurt, Sabri̇ Ateşalp, Alper Alemdaroğlu Jan 1999

The Evaluation Of Microanastomoses In Rats Withcolor Doppler Ultrasonography, Bahri̇ Üstünsöz, İbrahi̇m Somuncu, Mahmut Kömürcü, Mustafa Başşbozkurt, Sabri̇ Ateşalp, Alper Alemdaroğlu

Turkish Journal of Medical Sciences

Purpose: To evaluate the vascular patency of microanastomoses in rats with color Doppler ultrasonography. Materials and Methods: 15 superficial femoral and 15 carotid arterial end-to-end anastomoses were performed in 30 white rats. All arteries were evaluated pre- and post-operatively by color Doppler ultrasonography with a 7.5 mHz linear transducer (Acuson 128HP). All results were correlated with surgery after final Doppler evaluation. Results: The subjects were divided into three groups: (a) patent anastomosis; (b) partial occlusive anastomosis; (c) total occlusive anastomosis. The predictive value ratios for the patency group was 100% (15/15), that for the partial occlusive group was 67% (6/9) …


The In Vitro Effect Of Plasmodium Bergheiantigen Lysate On Natural Killer (Nk) Cellcytotoxic Activity, Cemaletti̇n Albayi̇, Ayşegül Yücel, Kemal Çeber, Turgut İmi̇r Jan 1999

The In Vitro Effect Of Plasmodium Bergheiantigen Lysate On Natural Killer (Nk) Cellcytotoxic Activity, Cemaletti̇n Albayi̇, Ayşegül Yücel, Kemal Çeber, Turgut İmi̇r

Turkish Journal of Medical Sciences

Plasmodium berghei is the rodent equivalent of Plasmodium falciparum which causes cerebral malaria in humans. However, P. berghei does not cause cerebral malaria in BALB/c mice, instead it leads to parasitemia, fever and some degree of liver damage. Although different aspects of immunological response have been intensively investigated in malaria; this the first time the in vitro effect of P. berghei antigen lysate on murine NK cytotoxic activity was studied. It was observed that this parasite antigen lysate suppresed the cytolytic activity of NK cells in a dose-dependent manner. Because the suppression of NK cell activity in a dose-dependent manner …


Generalized Bcg Lymphadenitis In An Infant:Diagnostic Dilemma With Lepromatous Leprosyand Gaucher Disease On Fine Needle Aspiration, Mustafa Hacimustafaoğlu, Mehmet Okan, Ömer Yerci̇, Suna Gedi̇koğlu, İrfan Kiriştioğlu, İbrahi̇m Ildirim Jan 1999

Generalized Bcg Lymphadenitis In An Infant:Diagnostic Dilemma With Lepromatous Leprosyand Gaucher Disease On Fine Needle Aspiration, Mustafa Hacimustafaoğlu, Mehmet Okan, Ömer Yerci̇, Suna Gedi̇koğlu, İrfan Kiriştioğlu, İbrahi̇m Ildirim

Turkish Journal of Medical Sciences

A two-year old male infant with generalized BCG lymphadenitis is presented. There was no obvious immunodeficiency disorder detected in the patient. BCG vaccine had been given at two months of age, and the lymphadenopathy developed at 21 months of age. Fine needle aspiration biopsy of the lymph node on Giemsa stain revealed macrophages very similar to Gaucher cells. These cells also resembled macrophages seen in lepromatous leprosy. They were engorged with acid fast bacilli and had streaked or wrinkled cytoplasm. Mycobacterium bovis was cultured from the lymph nodes and the patients improved with antituberculous therapy.


Infantile Galactosialidosis Associated Withvitamin D Deficiency Rickets, Koray Boduroğlu, Ergül Tunçbi̇lek, Turgay Coşkun, Canan Uçar Jan 1999

Infantile Galactosialidosis Associated Withvitamin D Deficiency Rickets, Koray Boduroğlu, Ergül Tunçbi̇lek, Turgay Coşkun, Canan Uçar

Turkish Journal of Medical Sciences

Galactosialidosis is an autosomal recessive disease with combined deficiency of two lysosomal enzymes due to the lack of a protective protein. We report on a boy with infantile galactosialidosis who has an intermediate phenotype and vitamin D deficiency rickets. Due to the possible role of vitamin D deficiency in the pathogenesis of dysostosis multiplex we recommend that patients with lysosomal storage disease should be supplemented with vitamin D.


Nadph-Diaphorase-Reactive Neurons In Rat Basal Ganglia, Gülgün Kayalioğlu, Fi̇gen Gövsa, Mete Ertürk Jan 1999

Nadph-Diaphorase-Reactive Neurons In Rat Basal Ganglia, Gülgün Kayalioğlu, Fi̇gen Gövsa, Mete Ertürk

Turkish Journal of Medical Sciences

NADPH-d reaction was performed on nine male Sprague-Dawley rats and morphometry of NADPH-d(+) cells was investigated in caudate-putamen, globus pallidus and ventral pallidum. In caudate-putamen we observed intensely stained NADPH-d (+) cells. Maximum diameter and minimum diameters of the NADPH-d (+) cells in caudate-putamen was measured as 19.19±0.04 \mum and 10.42±0.12 \mum, consequently. In globus pallidus, moderately stained NADPH-d (+) cells were observed. We measured the maximum and minimum diameters of the NADPH-d (+) cells as 19.93±0.24 \mum and 10.42±0.12 \mum, consequently. In ventral pallidum, medium-sized, moderately stained cells were present. Maximum and minimum diameters of the NADPH-d (+) cells …


Protein C, Protein S And Antithrombin Iii Levelsin A Rabbit Sepsis Model, Mehmet Totan, Cengi̇z Di̇lber, Davut Albayrak Jan 1999

Protein C, Protein S And Antithrombin Iii Levelsin A Rabbit Sepsis Model, Mehmet Totan, Cengi̇z Di̇lber, Davut Albayrak

Turkish Journal of Medical Sciences

The consumption of coagulation inhibitors will augment coagulation triggered excessively in sepsis. The determination of levels of these inhibitors may open new substitution treatment schedules to overcome the plateau of the achieved improvement ratio with antimicrobial treatment. Staphylococcus aureus ATCC 25923, 1x10 9 per kg day for two days was administered intravenously to 30 albino rabbits to induce sepsis. Clinical and hematological signs were determined and sepsis was determined with blood culture. The complete blood count, protein C, protein S and antithrombin III levels were examined at the baseline and after sepsis development. The mean proportions of baseline to sepsis …


Immunohistochemical Study On Thepcna-Immunoreactivity In The Uterus Of Ratsovariectomized Or Treated With Antiestrogenclomiphene Citrate, Leyla Canpolat, İbrahi̇m Hani̇fi̇ Özercan, Nurten Bozlak, Cengi̇z Doğan Jan 1999

Immunohistochemical Study On Thepcna-Immunoreactivity In The Uterus Of Ratsovariectomized Or Treated With Antiestrogenclomiphene Citrate, Leyla Canpolat, İbrahi̇m Hani̇fi̇ Özercan, Nurten Bozlak, Cengi̇z Doğan

Turkish Journal of Medical Sciences

PCNA (proliferating cell nuclear antigen) immunoreactivity in the uterus of mature rats was investigated after long term administration of clomiphene citrate and ovariectomy. In the luminal epithelium and glandular epithelium and endometrial stroma regions, few PCNA-immunoreactive cells were observed. PCNA reactivity was estimated for the luminal and glandular epithelium and for the stromal cells. Treatment of clomiphene citrate decreased the proliferation of the luminal epithelial cell and stromal cells to the same extent as ovariectomy. In both of these groups, the proportion of anti-PCNA positive cells in the glandular epithelium was significantly higher than in the luminal epihelium and stromal …


Determination Of Viable Myocardium In Patientswith Ischaemic Left Ventricular Dysfunction:Comparison Of Thallium-201 Single-Photonemission Computed Tomography With Nitrateand Dobutamine Echocardiography, Mustafa Cemri̇, Ridvan Yalçin, Bülent Boyaci, Özlem Kapucu, Tamer Atasever, Ati̇ye Çengel, Övsev Dörtlemez, Hali̇s Dörtlemez Jan 1999

Determination Of Viable Myocardium In Patientswith Ischaemic Left Ventricular Dysfunction:Comparison Of Thallium-201 Single-Photonemission Computed Tomography With Nitrateand Dobutamine Echocardiography, Mustafa Cemri̇, Ridvan Yalçin, Bülent Boyaci, Özlem Kapucu, Tamer Atasever, Ati̇ye Çengel, Övsev Dörtlemez, Hali̇s Dörtlemez

Turkish Journal of Medical Sciences

The method of Thallium - 201- single - photon emission computed tomography (Tl-201 SPECT) have been commonly used to detect uncontractile but viable myocardium in patients with ischemic left ventricular dysfunction. The aim of this study was to establish the value of nitrate echocardiography (NE) and low dose dobutamine echocardiography (LDDE) to detect viable myocardium when compared to Tl-201 SPECT. Twently patients (16 M, 4F; mean age: 56.4±9.6 years) who had anterior myocardial infarction in the last three months were studied. Within the same week, but on different days NE, LDDE and Tl-201 SPECT procedures were performed to the patients. …


Neutrophil Chemotaxis In Acutely Infected Andclinically Stable Cystic Fibrosis Patients, Burçi̇n Şener, Gülşen Hasçeli̇k, Uğur Özçeli̇k, Ayfer Günalp, Ayhan Göçmen Jan 1999

Neutrophil Chemotaxis In Acutely Infected Andclinically Stable Cystic Fibrosis Patients, Burçi̇n Şener, Gülşen Hasçeli̇k, Uğur Özçeli̇k, Ayfer Günalp, Ayhan Göçmen

Turkish Journal of Medical Sciences

Brochopulmonary infection in cystic fibrosis (CF) patients is associated with chronic progressive lung disease. The role of host factors, such as neutrophil functions, in the progressive pathologic processes in the respiratory tract of these patients, is poorly defined. Neutrophil chemotaxis is one of the first mechanisms of host defense to become activated after bacterial invasion has occurred. This study was aimed to evaluate the role of neutrophil chemotaxis in CF and also to determine whether an acute bacterial infection and the nutritional status can affect neutrophil chemotaxis or not. Twelve acutely infected and 12 clinically stable CF patients and 10 …


Characterization Of Catalytic Phenotype Of \Beta-Galactosidasefrom Laci Mutant, E. Coli Csh-36,As A Tool For The Management Of Lactoseintolerance, Ayşegül Ayyildiz Jan 1999

Characterization Of Catalytic Phenotype Of \Beta-Galactosidasefrom Laci Mutant, E. Coli Csh-36,As A Tool For The Management Of Lactoseintolerance, Ayşegül Ayyildiz

Turkish Journal of Medical Sciences

Objectives: Lactose intolerance is a common public health problem with 5-100% prevalance among different populations of the world. Use of \beta-galactosidase to reduce the lactose content in food or consumption of special products of milk or exogeneous lactase enzyme are among the approaches taken to manage lactose intolerance. Recombinant \beta -galactosidase as well as \beta -galactosidase derived from different sources have variances in their bioefficiency. Thermodynamic properties of \beta -galactosidase determines the industrial efficiency. In this \beta -galactosidase from E. coli CSH-36, a constitutive expressor of enzyme was investigated for enzyme biofunctionality. Methods: The enzyme was purified by cell lysis, …


Dose Dependent Changes In The Cristaneuroepitheium Resulting From Gentamicinototoxicity In The Chinchilla, Hasan Tanyeri̇, Ivan Lopez, Larry Hoffman Jan 1999

Dose Dependent Changes In The Cristaneuroepitheium Resulting From Gentamicinototoxicity In The Chinchilla, Hasan Tanyeri̇, Ivan Lopez, Larry Hoffman

Turkish Journal of Medical Sciences

This experiment was conducted to investigate the dose-dependent effects of gentamicin (GM) on the neuroepithelial morphology of the posterior crista ampullares (PCA) of the adult chinchilla. The experiment focused on hair cell (HC) morphology to monitor GM's dose-dependent effects and also to define an ototoxically-efficient and safe dose what would subsequently be used in a time course study. Chinchillas (n=13) were treated with subcutaneous (SC) daily doses of 120 mg/kg, 60 mg/kg, and 30 mg/kg GM, respectively, for six days. Light microscopy observations were made from the excised PCA of two animals from each group that survided the complete treatment …


The Effects Of Smoking On Glutathione Levels Inbronchoalveolar Lavage Fluid, Füsun Alataş, Necla Özdemi̇r, Özkan Alataş, Si̇nan Ergi̇nel, Muzaffer Meti̇ntaş, Rana Işik Jan 1999

The Effects Of Smoking On Glutathione Levels Inbronchoalveolar Lavage Fluid, Füsun Alataş, Necla Özdemi̇r, Özkan Alataş, Si̇nan Ergi̇nel, Muzaffer Meti̇ntaş, Rana Işik

Turkish Journal of Medical Sciences

Cigarette smoke contains high concentrations of oxidants and reactive oxygen species. The aim of this study was to evaluate the effect of long-term cigarette smoking on glutathione (GSH) levels in bronchoalveolar lavage (BAL) fluid. Nineteen current cigarette smokers and seven healthy nonsmoking volunteers were included in the study. BAL was performed by infusion of five sequential 20 ml aliquots and each aliquot was immediately aspirated. The levels of GSH were determined in BAL fluids. The epithelial lining fluid volume was calculated by the ratio of urea concentration in BAL fluid to that in serum. Lower GSH levels were observed in …


A Combined Variation Of The Arteries And The Nerve In A Leg, Zeli̇ha Kurtoğlu, M. Haluk Uluutku Jan 1999

A Combined Variation Of The Arteries And The Nerve In A Leg, Zeli̇ha Kurtoğlu, M. Haluk Uluutku

Turkish Journal of Medical Sciences

During the dissection of an amputed leg, we discovered a combined variation involving the branching of the popliteal artery and tibial nerve. The popliteal artery showed a trifurcation pattern, and one of its branches, the posterior tibial artery, was hypoplastic. In addition, a small branch arising from the tibial nerve in the upper part of the leg distally crossed the peroneal artery and contributed to the medial plantar nerve. In this article, such a case of embryonic origin is discussed, along with the clinical significance of these variations. The variant nerve and its relationship with the variant artery have not …


Faculty Publications 1998, Lsu Health Sciences Center New Orleans Jan 1999

Faculty Publications 1998, Lsu Health Sciences Center New Orleans

Historical Faculty Publications

This Faculty bibliography contains 822 publications.


Agnors, Pcna And Histologic Activity Index Inchronic Liver Disease, Koray Ceyhan, İlkser Akpolat, İbrahim Kobat, Nazan Bozdoğan, Selim Erekul Jan 1999

Agnors, Pcna And Histologic Activity Index Inchronic Liver Disease, Koray Ceyhan, İlkser Akpolat, İbrahim Kobat, Nazan Bozdoğan, Selim Erekul

Turkish Journal of Medical Sciences

Chronic hepatitis is a clinical and pathological syndrome, which has several causes and it is characterized by varying degrees of hepatocellular necrosis and inflammation. Several systems have been proposed to evaluate the diagnosis, grading and staging of chronic hepatitis. A histologic activity index (HAI) has been developed which generates a numerical score for liver biopsy specimens obtained from patients with chronic hepatitis. The aim of this study was to evaluate the correlation between HAI and proliferative activity markers, such as PCNA and AgNORs in biopsy specimens obtained from patients with chronic liver disease including chronic hepatitis and cirrhosis. Mean AgNOR …


Diurnal Variation Of Methotrexatepharmacokinetics In Adults With Osteosarcoma, Necdet Soykan, Mehtap Çinar, Cenk Can, Banu Çiçek Bi̇lkay Jan 1999

Diurnal Variation Of Methotrexatepharmacokinetics In Adults With Osteosarcoma, Necdet Soykan, Mehtap Çinar, Cenk Can, Banu Çiçek Bi̇lkay

Turkish Journal of Medical Sciences

The daytime and nighttime dispositions of high dose (12 g/m 2 ) methotrexate were examined in 8 osteosarcoma patients. The plasma and renal clearances, urine pH values and area under the curves were compared. The plasma clearance of methotrexate tended to fall after it was administered at (from 1.74±0.06 ml/min/kg to 0.47±0.01 ml/min/kg, p


Effect Of Psychological Stress On Nasal Immunity, Erdal Seren, Abdülcemal Ümit Işik, Mehmet İmamoglu, Osman Bahadir, Mehmet Arif Köroğlu, Yavuz Tekeli̇oğlu Jan 1999

Effect Of Psychological Stress On Nasal Immunity, Erdal Seren, Abdülcemal Ümit Işik, Mehmet İmamoglu, Osman Bahadir, Mehmet Arif Köroğlu, Yavuz Tekeli̇oğlu

Turkish Journal of Medical Sciences

Stress activates the hypotalamic-pituitary- adrenal axis, increases circulating glucocorticoids, and is associated with alterations in immune functions. Nasal mucosa is richly innervated by sympathetic nerve fiber and nasal patency changes in response to various sympathetic stimuli. These fibres form close neuroeffector junctions with lymphocytes and macrophages. Nasal lavage and peripheral blood samples were collected from healthy medical students one hour before their exams and a week later, after the declaration of results of the exams were announced. We determined and compared the distribution of T lymphocyte subsets in students under psychological stress The T cell: natural killer cell, T helper …


The Assessment Of Anthropometrical Measurements Of Newborns And The Incidence Of Fetal Malnutrition In Erzurum Region, Zerrin Orbak, Hüseyin Tan, Nevin Sağsöz, Fatih Zor Jan 1999

The Assessment Of Anthropometrical Measurements Of Newborns And The Incidence Of Fetal Malnutrition In Erzurum Region, Zerrin Orbak, Hüseyin Tan, Nevin Sağsöz, Fatih Zor

Turkish Journal of Medical Sciences

We included in this study 1100 newborns whose gestational ages were between 26 and 42 weeks. Of these infants, 323(29.4%) were preterm. The others 777(70.6%) were term infants. In term newborns, the mean weight, length, head circumference and ponderal indexes of males were significantly higher than those of females (p


Nosocomial Urinary Tract Infections In Children, Ayse Balat, L. Leighton Hill Jan 1999

Nosocomial Urinary Tract Infections In Children, Ayse Balat, L. Leighton Hill

Turkish Journal of Medical Sciences

Nosocomial infections are a major cause of morbidity and mortality in hospitalized children, and the urinary tract is one of the most common sites of these infections. We retrospectively reviewed the charts of 1,221 children discharged with a diagnosis of urinary tract infection (UTI) from July 1, 1991 to June 30, 1994. Of the 1,221 UTIs, there were 137 (11.2%) cases of nosocomial UTI (NUTI) in 136 patients. NUTI accounted for 0.28% of all discharges (48, 382 patients) at a single institution over the 3-year period studied. There were 75 girls and 61 boys. The mean age was 4.4 years …


Effect Of Dehydration On The Pharmacokinetics Of Mefenamic Acid, Shadab Qamar, Nadeem Irfan, Mahmood Ahmad, Muhammad Jamshaid, Naeem A. Muzaffar Jan 1999

Effect Of Dehydration On The Pharmacokinetics Of Mefenamic Acid, Shadab Qamar, Nadeem Irfan, Mahmood Ahmad, Muhammad Jamshaid, Naeem A. Muzaffar

Turkish Journal of Medical Sciences

The pharmacokinetic properties and bioavailability of mefenamic acid was studied in normal and dehydrated rabbits. High perfomance liquid chromatography (HPLC) was used for the assay of mefenamic acid in plasma samples. The mean plasma concentration and area under the plasma concentration-time curve decreased but the volume of distribution and total body clearance increased significantly (P


A Novel Clinical And Laboratory Based Approach To Coronary Heart Disease: Relationship Between Angiography Findings, Antioxidant Enzymes And No, Bülent Sözmen, Fevzi̇ye Uysal, Dervi̇ş Gazi̇tepe, Leyla Aslan, Eser Yildirim Sözmen Jan 1999

A Novel Clinical And Laboratory Based Approach To Coronary Heart Disease: Relationship Between Angiography Findings, Antioxidant Enzymes And No, Bülent Sözmen, Fevzi̇ye Uysal, Dervi̇ş Gazi̇tepe, Leyla Aslan, Eser Yildirim Sözmen

Turkish Journal of Medical Sciences

Atherosclerosis is the most common manifestation of cardiovascular disease. However the exact mechanisms that take place in its pathogenesis have not yet been completely understood. Free radicals and lipid peroxidation may play an important role in the pathogenesis of atherosclerosis and endothelial dysfunction also may be an aggravating factor in this process. Unfortunately all of the previous studies have focused on the atherosclerotic tissue. Our aim was to establish a relationship between the antioxidant enzymes and plasma nitrate as an index of whole-body, endogenous nitric oxide production in coronary heart disease and also the relationship between these parameters and the …


Urinary Serotonin And 5-Hydroxyindolacetic Acid Levels In Preeclampsia, Pervi̇n Vural, Cemi̇l Akgül, Mukaddes Canbaz, Alkan Yildirim Jan 1999

Urinary Serotonin And 5-Hydroxyindolacetic Acid Levels In Preeclampsia, Pervi̇n Vural, Cemi̇l Akgül, Mukaddes Canbaz, Alkan Yildirim

Turkish Journal of Medical Sciences

The role of serotonin in the pathogenesis of hypertension which is one of the main symptoms of preeclampsia is of growing importance. The levels of serotonin (5-Hydroxytryptamin or 5-HT) and its metabolite, 5-Hydroxyindolacetic acid (5-HIAA) in twenty-four hour urine samples taken from severe preeclamptic and normotensive pregnant women were determined by colon chromotography and spectrophotometry. In preeclamptic pregnant women there was a significant increase in 5-HT levels (P