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Articles 43921 - 43950 of 45148

Full-Text Articles in Medicine and Health Sciences

The Anti-Inflammatory Effects Of N^G-Nitrol-Arginine (L-Name) And Steroid In Concanavalina-Induced Uveitis, Hamdi̇ Er, Erhan Üzmez, Naki̇ Doğan, Tongabay Cumhurcu Jan 1999

The Anti-Inflammatory Effects Of N^G-Nitrol-Arginine (L-Name) And Steroid In Concanavalina-Induced Uveitis, Hamdi̇ Er, Erhan Üzmez, Naki̇ Doğan, Tongabay Cumhurcu

Turkish Journal of Medical Sciences

The objective of this study was to compare the anti-inflammatory effects of NG -nitro L-arginine (L-NAME) and corticosteroid in Concanavalin A-induced uveitis in rats. Sixteen male Wistar rats were used. After general anesthesia, intravitreal 0.1 ml Concanavalin A (100mg/ml) was injected into the left eyes of the rats. The animals were divided into 3 groups: group 1 (6 animals) received intraperitoneal 0.2 ml L-NAME (200 mg/kg) 1 hour before, 1 day and 3 days after Concanavalin A injection, group 2 (6 animals) received tropical 1% prednisolone acetate four times a day for 3 weeks, group 3 (4 animals) received an …


Immunohistochemical Localization Of Thymosin\Beta_4 In Bovine Tissuesourania E. Tsitsilonis 1, Ourania E. Tsitsilonis, Ayhan Ulubelen, Stanka Stoeva, Mirna Mihelic Rapp, W. Giebel, Rai̇ner Lehmann, Wolfgang Voelter Jan 1999

Immunohistochemical Localization Of Thymosin\Beta_4 In Bovine Tissuesourania E. Tsitsilonis 1, Ourania E. Tsitsilonis, Ayhan Ulubelen, Stanka Stoeva, Mirna Mihelic Rapp, W. Giebel, Rai̇ner Lehmann, Wolfgang Voelter

Turkish Journal of Medical Sciences

The histochemical localization of thymosin \beta_4 was investigated for the first time in several bovine tissues, using the indirect immunofluorescent technique and the newly applied alkaline phosphatase anti-alkaline phosphatase (APAAP) antibody method. A polyclonal antiserum raised against the N-terminal fragment (1-14) of thymosin \beta_4, showing less than 0.1% crossreactivity with the second b-thymosin in calf tissues, thymosin \beta_9, was used. Positive reaction for thymosin \beta_4 was observed in the cytoplasm of all tissues studied, i.e., bovine spleen, thymus, lung, liver, kidney, lymph nodes and cardiac muscle. The highest staining intensity was found in the cytoplasmic area of spleen and thymus, …


Prevention Of Recurrences Afterthyroidectomy In An Endemic Area Withprophylactic Levothyroxine Use, Adnan Çalik, Uzer Küçüktülü, Yavuz Bi̇lgi̇n, Aki̇f Çi̇nel, Etem Alhan, Burhan Pi̇şki̇n Jan 1999

Prevention Of Recurrences Afterthyroidectomy In An Endemic Area Withprophylactic Levothyroxine Use, Adnan Çalik, Uzer Küçüktülü, Yavuz Bi̇lgi̇n, Aki̇f Çi̇nel, Etem Alhan, Burhan Pi̇şki̇n

Turkish Journal of Medical Sciences

This study was planned to compare recurrence of goiters after thyroidectomy in patients who received prophylactic levothyroxine and patients who received no therapy. One hundred and twenty-six patients had been treated by bilateral subtotal thyroidectomy in the General Surgery Clinic of Karadeniz Technical University from 1987 to 1992. Eithy-eight of these patients were included in this study while the remaining patients were excluded as they were non contactable. They were divided into two groups. In group 1, there were 41 patients who had received prophylactic therapy with thyroxine 100 micro grams daily for a period of 9 to 12 months. …


Decreasing Selenium Levels Andglutathione Peroxidase Activity In Patientswith Cutaneous Leishmaniasis, Abdurrahi̇m Koçyi̇ği̇t, Özcan Erel, Mehmet Sali̇h Gürel, Adnan Seyrek, Necmeddi̇n Aktepe, Selahatti̇n Gür, Senel Avci Jan 1999

Decreasing Selenium Levels Andglutathione Peroxidase Activity In Patientswith Cutaneous Leishmaniasis, Abdurrahi̇m Koçyi̇ği̇t, Özcan Erel, Mehmet Sali̇h Gürel, Adnan Seyrek, Necmeddi̇n Aktepe, Selahatti̇n Gür, Senel Avci

Turkish Journal of Medical Sciences

For most infectious diseases, increased formation of reactive oxygen species is secondary to the primary disease process. Some microorganisms are highly susceptible to exogenous reactive oxygen species such as hydrogen peroxide. Glutathione peroxidase (GSH-Px) remove H 2 O 2 , and selenium is requird for the activity of GSH-Px. Therefore, to assess the status of GSH-Px and selenium in cutaneous leishmaniasis (CL), we determined serum selenium concentration and blood GSH-Px activity in 52 patients with CL and in 38 healthy controls. Selenium concentrations and GSH-Px activities were found to be lower in the patient group than in the controls (p


The Role Of Serum Lipids On Cyclosporine-Inducedgingival Overgrowth In Renal Transplantpatients, Tunç İlgenli̇, Gül Ati̇lla, Mustafa Ci̇ri̇t, Nezi̇h Azmak Jan 1999

The Role Of Serum Lipids On Cyclosporine-Inducedgingival Overgrowth In Renal Transplantpatients, Tunç İlgenli̇, Gül Ati̇lla, Mustafa Ci̇ri̇t, Nezi̇h Azmak

Turkish Journal of Medical Sciences

Cyclosporine-A (CsA) is widely used to prevent organ rejection in recipients of transplanted organs and also in the treatment of various systemic diseases. CsA has a number of side effects, including gingival overgrowth (GO). However, the pathogenesis of CsA-induced GO remains uncertain. It has been postulated that CsA alters fibroblast activity. CsA is transported in plasma by binding to lipid components. It is possible that changes in serum lipid levels could alter the interaction between the CsA and gingival fibroblasts within the gingival tissues. It has also been reported that CsA may alter serum lipid levels in the transplant population. …


Clinical And Histopathological Indicators Of Neckmetastasis In Laryngeal Carcinoma, Şefi̇k Hali̇t Akmansu, Hakan Korkmaz, Engi̇n Dursun, Seli̇m Sermet Erbek, Hakan Göçmen, Tuğba Ünal, Cavi̇t Özeri̇ Jan 1999

Clinical And Histopathological Indicators Of Neckmetastasis In Laryngeal Carcinoma, Şefi̇k Hali̇t Akmansu, Hakan Korkmaz, Engi̇n Dursun, Seli̇m Sermet Erbek, Hakan Göçmen, Tuğba Ünal, Cavi̇t Özeri̇

Turkish Journal of Medical Sciences

Determination of cervical metastasis preoperatively is very important in planning the treatment strategy in laryngeal carcinoma. In spite of vigorous clinical and detailed high technology radiological examinations, the occult metastasis rate is between 12-17% in No necks. In recent years most of the studies are related to the clinical and histopathological risk factors that may effect cervical metastasis. In this study we reviewed the primary tumors and neck specimens of laryngeal carcinoma patients operated in our clinic retrospectively. In 46 laryngeal carcinoma patients with laryngectomy and neck dissection, the following criteria were examined; Tumor localization, T status, histologic grading, peripheral …


Comparison Of Intubation Conditions Ofalfentanil And Propofol With Atracurium In Shortprocedures Of Children, Ahmet Can Şenel, Erdem Nai̇l Duman, Mevlüt Yurtseven, Gönül Aktürk Jan 1999

Comparison Of Intubation Conditions Ofalfentanil And Propofol With Atracurium In Shortprocedures Of Children, Ahmet Can Şenel, Erdem Nai̇l Duman, Mevlüt Yurtseven, Gönül Aktürk

Turkish Journal of Medical Sciences

We have assessed tracheal intubating conditions in 45 ASA I-II children, aged 4-14 years undergoing elective ear, nose and throat surgery. After the induction dose of propofol 2.5 mgkg -1 , group I received alfentanil 10 µgkg -1 , group II received alfentanil 20 µgkg -1 and group III received atracurium 0.5 mgkg-1 for tracheal intubation. The mean arterial pressure (MAP), heart rate (HR), arterial oxygen saturation (SaO 2 ), end tidal carbondioxide (ETCO2) and intubation conditions were investigated. The quality of tracheal intubation was graded according to the ease of laryngoscopy, position of the vocal cords, coughing and jaw …


Autosomal Dominant Osteopetrosis Type Ii, Kazim Şenel, Si̇nan Sönmez, Lale Cerrahoğlu, Mahi̇r Uğur, Selami̇ Suma Jan 1999

Autosomal Dominant Osteopetrosis Type Ii, Kazim Şenel, Si̇nan Sönmez, Lale Cerrahoğlu, Mahi̇r Uğur, Selami̇ Suma

Turkish Journal of Medical Sciences

No abstract provided.


Ultrasound And Magnetic Resonance Imagingfindings Of Choroid Plexus Papilloma, Suat Eren, Pinar Polat, Yusuf Tüzün, Selami̇ Suma Jan 1999

Ultrasound And Magnetic Resonance Imagingfindings Of Choroid Plexus Papilloma, Suat Eren, Pinar Polat, Yusuf Tüzün, Selami̇ Suma

Turkish Journal of Medical Sciences

No abstract provided.


Neonatal Cerebral Candida Abscess: Radiologic And Clinical Findings, Ömer Cevi̇t, Hulusi̇ Eği̇lmez, Hayri̇ B. Toksoy, Di̇lara İçağasioğlu, Turan Sarikaya, İdri̇s Sütçü Jan 1999

Neonatal Cerebral Candida Abscess: Radiologic And Clinical Findings, Ömer Cevi̇t, Hulusi̇ Eği̇lmez, Hayri̇ B. Toksoy, Di̇lara İçağasioğlu, Turan Sarikaya, İdri̇s Sütçü

Turkish Journal of Medical Sciences

No abstract provided.


The Use Of Polypeptide Probes Selected Fromartificial Peptide Libraries For The Recognitionand Differentiation Of Dna Sequences, Erol Ömer Atalay, Berri̇n Erdağ, Beyazit Çirakoğlu Jan 1999

The Use Of Polypeptide Probes Selected Fromartificial Peptide Libraries For The Recognitionand Differentiation Of Dna Sequences, Erol Ömer Atalay, Berri̇n Erdağ, Beyazit Çirakoğlu

Turkish Journal of Medical Sciences

In the novel approach suggested here, we examined the use of polypeptide probes selected from artificial peptide libraries for the identification of the differences in dsDNA sequences which are potential targets for the genetic diseases. As a model system two target DNAs which are the polymerase chain reaction (PCR) products of the two hage-display vector multiple cloning sites (MCS) differing at 18 base pair long has been used. In the production of the target sequences biotinylated primers were used in PCR. The polypeptide probes obtained from artificial peptide library by the selection of phage-display techniques. Identified clones bearing the candidate …


Technical Approach To Generate Polyclonalantibodies Against Bacterially Expressed Gst-Pyk-C: Evaluation Of Cross-Reaction Andrecognition In Some Mammalian And Yeast Celllysates, Ayşegül Ayyildiz Jan 1999

Technical Approach To Generate Polyclonalantibodies Against Bacterially Expressed Gst-Pyk-C: Evaluation Of Cross-Reaction Andrecognition In Some Mammalian And Yeast Celllysates, Ayşegül Ayyildiz

Turkish Journal of Medical Sciences

Pyk-2 is a protein tyrosine kinase, highly expressed in human hippocampus, dentate gyrus and olfactory bulb. In this study, polyclonal antibodies against the C-terminal of pyk-2, starting from Pro-759, were generated by injecting rabbits with the bacterially expressed GST fusion construct, generated by cloning the C-terminal domain of pyk-2 into pGEX-3X vector and affinity purification to increase the specificity of recognition. Anti-pyk-C was shown to recognize a 123 kD band in Western Blots of 293 cells transfected with pyk-2, as well as PC-12, COS and 3T3 cells and not to cross-react with FAK transfected Sf-21 lysates, in spite of high …


Opioid Modulation Of The Pre-Ovulatory Lh Surge In The Conscious Rat: Involvement Of Indolamines, Bayram Yilmaz, Desmond P. Gilmore Jan 1999

Opioid Modulation Of The Pre-Ovulatory Lh Surge In The Conscious Rat: Involvement Of Indolamines, Bayram Yilmaz, Desmond P. Gilmore

Turkish Journal of Medical Sciences

Endogeonus opioid peptides play an important role in the generation of the pre-ovulatory LH surge. We investigated the interrelationship between the oploid and indolaminergic systems in the regutalion of LH secretion, and the involvement of \mu-and \kappa-opioid subtypes in this process. Concsious female rats bearing cannula in the femoral artery were injected intraperitoneally with \mu-(diamorphine) and \kappa -(U-50488H) opioid agonists either alone or with their respective antagonists, naloxone and MR2266, on pro-oestrus. Blood samples were collected hourly between 15.00 and 19.00 and plasma LH levels were measured by RIA. 5-HT and 5-HIAA concentrations were determined by HPLC-ECD in the MPOA, …


Effects Of Cyclosporin A On Rat Pancreatic \Beta And Dcells And Glucose Levels (An Immunocytochemicalstudy), Kadri̇ Güven, Fi̇gen Öztürk, Fahretti̇n Keleşti̇mur Jan 1999

Effects Of Cyclosporin A On Rat Pancreatic \Beta And Dcells And Glucose Levels (An Immunocytochemicalstudy), Kadri̇ Güven, Fi̇gen Öztürk, Fahretti̇n Keleşti̇mur

Turkish Journal of Medical Sciences

The effects of cyclosporin A (CsA) on rat pancreatic islet \beta and D cells and plasma glucose levels at doses of 50 mg/kg body weight applied for 20 days were investigated. Fifteen Swiss Albino rats were used as the study group and 5 were the control group. Rat pancreatic islet \beta and D cells were stained immunocytochemically by anti-insulin and anti-somatostation antibodies. \beta and D cells from 15 different islets were evaluated qualitatively and quantitatively. Plasma glucose changes were also compared between the study and the control group. The pancreas morphology was found to be normal in both groups by …


The Effects Of Hyaluronic Acid On Myringoplasty Inrats, Ahmet Kutluhan, Serdar Uğraş, Emi̇n İnalkaç, Nusret Akpolat Jan 1999

The Effects Of Hyaluronic Acid On Myringoplasty Inrats, Ahmet Kutluhan, Serdar Uğraş, Emi̇n İnalkaç, Nusret Akpolat

Turkish Journal of Medical Sciences

Tympanic membrane perforations arise from a variety of causes. Some of them require myringoplasty. In this study, we used hyaluronic acid, a polysaccharide with high-molecular- weight which may be obtained commercially and affects modulations of cell function. An experimental myringoplasty was performed on rats in which a chronic dry tympanic membrane perforation was formed. While physiological saline was embedded in Gelfoam ® which was supported under and over the graft, in group 1, hyaluronic acid embedded gelfoam was used in group 2. Better epithelization, less calcification and scar tissue were established in group 2 myringoplasties. This study shows that hyaluronic …


The In Vitro Effects Of The Antimalarial Drug Primaquine, On The Activities Of Some Enzymes In Human Erythrocyte Lyzates, Meltem Müftüoğlu, Nazmi̇ Özer Jan 1999

The In Vitro Effects Of The Antimalarial Drug Primaquine, On The Activities Of Some Enzymes In Human Erythrocyte Lyzates, Meltem Müftüoğlu, Nazmi̇ Özer

Turkish Journal of Medical Sciences

The effect of primaquine on the enzymatic antioxidant defence mechanisms of erythrocytes were determined by measuring the activities of the below enzymes, before and after 30 minutes of incubation of hemolyzates with 1 mM primaquine at 37°C. Among the enzymes studied glucose-6- phosphate dehydrogenase seemed the most sensitive enzyme; 57 % and 78 % inhibition at zero (due to the binding of primaquine to NADP binding site) and 30 minutes of incubation (due to the reactive oxygen species), respectively. Catalase, superoxide dismutase, and glutathione-S-transferase were less sensitive to primaquine-derived reactive oxygen species: 33, 11, and 0 % inhibition at the …


Estimation Of The Prevalence Of A Disease From Screening Tests, Ergun Karaağaoğlu Jan 1999

Estimation Of The Prevalence Of A Disease From Screening Tests, Ergun Karaağaoğlu

Turkish Journal of Medical Sciences

Since most secreening tests are not 100% accurate, the proportion of subjects screened positive in such a test cannot be used as an estimate of the population prevalence. Methods which take sensitivity and the specificity into consideration should be employed in such circumstances. Estimation of the population prevalence as defined by Gartand Buck may produce results which are outside the range of 0 to 1. A Bayesian approach avoids results of this kind, but requires complicated computations. Lew and Levy proposed an approximation to the Bayesian estimate of the population prevalence. To simplify the computations, I propose a method which …


Spinal Anesthesia In Children With Rectalpremedication With Midazolam, Ketamine Andatropine, Bi̇nnur Sarihasan, Si̇bel Bariş, Fadi̇me Yeşi̇ltaş, Ayla Tür, Haydar Şahi̇noğlu, Emre Üstün, Fuat Güldoğuş, Deni̇z Karakaya, Zeynep Kayhan Jan 1999

Spinal Anesthesia In Children With Rectalpremedication With Midazolam, Ketamine Andatropine, Bi̇nnur Sarihasan, Si̇bel Bariş, Fadi̇me Yeşi̇ltaş, Ayla Tür, Haydar Şahi̇noğlu, Emre Üstün, Fuat Güldoğuş, Deni̇z Karakaya, Zeynep Kayhan

Turkish Journal of Medical Sciences

This study was designed to investigate the anxiolytic effects as well as acceptance of spinal anesthesia after rectally administered midazolam, ketamine and atropine for postoperative sedation in children. Spinal anesthesia is an easy and safe method in the pediatric age group especially for outpatients. Spinal anesthesia was administered to 20 patients, aged between 2 months and 2 years, premedicated with 0.5 mg/kg midazolam + 5 mg/kg ketamine + 0.02 mg/kg atropine rectally. During vein puncture 14 children were asleep, 5 children were anxious and 1 child was crying and during spinal anesthesia 7 children were asleep, 10 children were anxious …


The Comparison Of The Efficacy Aerobic Exercisesversus Strengthening, Stretching Andmobilization Exercises In Subacute And Chroniclow Back Pain, Ayşe Karan, Lütfi̇ye Müslümanoğlu, Semi̇h Aki, Mustafa Fi̇li̇z, Emel Özcan Yildiz, Ender Berker Jan 1999

The Comparison Of The Efficacy Aerobic Exercisesversus Strengthening, Stretching Andmobilization Exercises In Subacute And Chroniclow Back Pain, Ayşe Karan, Lütfi̇ye Müslümanoğlu, Semi̇h Aki, Mustafa Fi̇li̇z, Emel Özcan Yildiz, Ender Berker

Turkish Journal of Medical Sciences

The aim of this study was to investigate and compare the efficacy of aerobic exercises versus strengthening, stretching and mobilization exercises in patients with subacute or chronic low back pain. Forty patients were recruited for the study and randomly allocated to two groups. All patients were evaluated at admission, mid-treatment and termination of the program by visual analog scale (VAS), face scale, weekly analgesic intake and Million visual analog scale for pain. They were also scored by Roland-Morris scale and Oswestry scale for functional impairment. Beck depression inventory was used to evaluate depression and lumbar range of motion was measured …


The Evaluation Of Elongated Styloid Process In Panoramic Radiographs In Edentulous Patients, Memduha Gülhal Bozkir, Hasan Boğa, Fahri̇ Dere Jan 1999

The Evaluation Of Elongated Styloid Process In Panoramic Radiographs In Edentulous Patients, Memduha Gülhal Bozkir, Hasan Boğa, Fahri̇ Dere

Turkish Journal of Medical Sciences

It has been estimated that between 2% to 28% of the general adult population has radiographic evidence of elongated styloid process. In adults, the mean radiographic lenght of the styloid process is 20 to 30 mm and its tip is located between the external and internal carotid arteries, just lateral to the tonsillar fossa. Eagle's syndrome occurs when an elongated styloid process or ossified stylohyoid ligament causes recurrent throat pain or foreign body sensation, dysphagia, or facial pain. It may develop inflammatory changes or impinge on the adjacent arteries or sensory nerve endings, leading to the symptoms described. To study …


Accuracy Of Sphygmomanometers, Okay Başak, Şebnem Karazeybek Jan 1999

Accuracy Of Sphygmomanometers, Okay Başak, Şebnem Karazeybek

Turkish Journal of Medical Sciences

One of the factors affecting the accuracy of readings of blood pressure is the equipment used. Defects or inaccuracy of aneroid sphygmomanometers may be source of error in blood pressure measurement. We inspected 100 sphygmomanometers for physical defects and assessed their accuracy against a standard mercury manometer at four different pressure points. 46 of the 100 sphygmomanometers were determined to be intolerant (deviation from the mercury manometer by greater than±3 mm Hg at two or more of the test points). There were faults in the inflation-deflation system of 34 sphygmomanometers. The most common physical defects were: defective pump bulb, defective …


Chromosome 2 Fragility- 48, Xxyy Syndrome, Öztürk Özdemi̇r, E. Ferda Perçi̇n, İlhan Sezgi̇n Jan 1999

Chromosome 2 Fragility- 48, Xxyy Syndrome, Öztürk Özdemi̇r, E. Ferda Perçi̇n, İlhan Sezgi̇n

Turkish Journal of Medical Sciences

No abstract provided.


Diastolic Dysfunction: Pathogenesis, Therapy Andthe Importance Of Doppler Echocardiography, Fati̇h Yalçin, James Thomas Jan 1999

Diastolic Dysfunction: Pathogenesis, Therapy Andthe Importance Of Doppler Echocardiography, Fati̇h Yalçin, James Thomas

Turkish Journal of Medical Sciences

Diastolic dysfunction is characterized by increased resistance to ventricular filling, inappropriate upward shift of the diastolic pressure-volume relationship and exercise intolerance. Inappropriate tachycardia, decreased diastolic compliance and impaired systolic relaxation lead to diastolic dysfunction. Optimal therapy will depend on the type and pathophysiologic phase of disease. Doppler echocardiography is a valuable tool to diagnose diastolic dysfunction and therapeutic effects of drugs on diastolic function in different groups of patients. Recently a lot of studies have been going on this subject.


Cloning And Transcriptional Activation Of Thevitamin D Receptor (Amphibians)1, Meral Güzey Jan 1999

Cloning And Transcriptional Activation Of Thevitamin D Receptor (Amphibians)1, Meral Güzey

Turkish Journal of Medical Sciences

The vitamin D receptor (VDR), a member of the nuclear receptor superfamily, is an integral part of the body's calcium regulatory system. Mammalian and avian VDR genes were isolated, sequenced and characterized. In this study we cloned the vitamin D receptor from amphibians. We received a cDNA library prepared from amphibian (frog) tissues and prepared a cDNA probe based on the avian VDR. We screened the library and located the positive clones. Complete structure of VDR gene has been compared with other species and concluded that it shares 79%, 73%, 73% and 75% identity at the aminoacid level with the …


The Effect Of Dietary Calcium Intake On Plasma Renin Activity And Parathormon In Deoxycorticosteron Salt Hypertension, Ali̇ Gözey, Besi̇m Özaykan, Sai̇me Paydaş, Ayşe Doğan Jan 1999

The Effect Of Dietary Calcium Intake On Plasma Renin Activity And Parathormon In Deoxycorticosteron Salt Hypertension, Ali̇ Gözey, Besi̇m Özaykan, Sai̇me Paydaş, Ayşe Doğan

Turkish Journal of Medical Sciences

The effects of diets containing 2% and 4% calcium (Ca) on deoxycorticosteron (DOC) salt hypertension were studied in 29 male rats weighting 210-260 g. Rats were categorized into four groups: Group I: control rats (6), group II: DOC hypertensive group (n=8), group III: DOC-low Ca diet (2% CaCl 2 ) (8) and group IV: DOC-high Ca diet (4% CaCl_2 ) (n=7). During the six weeks follow up period, indirect systolic blood pressure (SBP) was highest in group II while it was found to be less increased in group III and IV. Weight increase was lowest in group IV (P


The Therapeutic Effect Of Nifedipine As A Ca+2entry Blocker On Experimental Transientischemic Retina, Murat Kaya, Cemal Gündoğdu Jan 1999

The Therapeutic Effect Of Nifedipine As A Ca+2entry Blocker On Experimental Transientischemic Retina, Murat Kaya, Cemal Gündoğdu

Turkish Journal of Medical Sciences

We evaluated the effect of nifedip-ine, an L-type voltage sensitive Ca+2 channel (VSCC) blocker, on the onset of neuronal damage induced by transient ischemia of guinea pig retinas in vivo. The animals were divided into two groups. In the first group 2 mg/kg Nifedipine was administered intraperi-toneally, while only 2 cc/kg NaCl 0.9% solution was given to the second group thirty minutes before the ischemic insult. Seven days after the temporary ligation of bilateral common carotid arteries for 45 minutes, the animals were dispatched and the eyes were enucleated for histopathologic analysis. It was observed that in the Nifedipine treated …


Teratogenic Effects Of Electromagnetic Fields Onthe Skeletal Systems Of Rat Fetuses, Hi̇kmet Hassa, Ömer T. Yalçin, Ni̇lgün Basmak, Hamza Esen, Duygu Koyuncu, Nevi̇n Kurtdere, Reşat N. Aşti Jan 1999

Teratogenic Effects Of Electromagnetic Fields Onthe Skeletal Systems Of Rat Fetuses, Hi̇kmet Hassa, Ömer T. Yalçin, Ni̇lgün Basmak, Hamza Esen, Duygu Koyuncu, Nevi̇n Kurtdere, Reşat N. Aşti

Turkish Journal of Medical Sciences

OBJECTIVE: To evaluate the potential teratogenic effects of electromagnetic fields on the skeletal systems of rat fetuses. MATERIAL AND METHODS: Twenty-five pregnant rats, which had been exposed to electromagnetic fields with frequencies of vertical 50 Hz and horizontal 20 kHz and a total maximum intensity of 10 milligauss, during their pregnancies, were the study group, while 15 pregnant rats were the control group. One hunderd eighty-nine and 125 fetuses obtained from the study and the control group respectively, were evaluated for abnormalities and variations in the skeletal system. The chi-square test was used for the statistical analysis. RESULTS: Major abnormality, …


The Prevalance Of Diseases With Diarrhoeaamong Children Under Five Years Old In Differentsocio-Economical Levels, Ali̇ İhsan Bozkurt, Servet Özgür, Bi̇rgül Özçirpici Jan 1999

The Prevalance Of Diseases With Diarrhoeaamong Children Under Five Years Old In Differentsocio-Economical Levels, Ali̇ İhsan Bozkurt, Servet Özgür, Bi̇rgül Özçirpici

Turkish Journal of Medical Sciences

This study was carried out on a representative sample consisting of 429 households in Gaziantep. The prevalance of diseases with diarrhoea was found to be 22.9% among children under five years old in the two weeks preceding the survey. It was observed that 51.3% of children with diarrhoea were taken to a medical facility, the mean duration of the diarrhoea was 4.5±3.8 days, and the rate of children with diarrhoea during the preceding 24 hours was 11.8%. It was also determined that the rate of children with diarrhoea whose intake of fluids was increased was 65.1%, the ratio of children …


Treatment Of Cervical Spondylosis By Anteriorsubtotal Vertebrectomy And Iliac Bone Fusion, Mehmet Yaşar Kaynar, Pami̇r Erdi̇nçler, Ali̇ Kafadar, Murat Hanci, Emi̇n Özyurt, Ali̇ Çeti̇n Sarioğlu Jan 1999

Treatment Of Cervical Spondylosis By Anteriorsubtotal Vertebrectomy And Iliac Bone Fusion, Mehmet Yaşar Kaynar, Pami̇r Erdi̇nçler, Ali̇ Kafadar, Murat Hanci, Emi̇n Özyurt, Ali̇ Çeti̇n Sarioğlu

Turkish Journal of Medical Sciences

There is no ideal surgical technique for cervical spondylosis. The choice of surgical procedure remains controversial. A series of 25 patients who had undergone subtotal vertebrectomy and iliac bone fusion between 1985 and 1995 were reviewed. There were 19 men and 6 women with an average age of 55.6 years. All of the patients had cervical myelopathy and /or radiculopathy due to multi-level spondylosis and 7 with associated ossification of the posterior longitudinal ligament. In 6 patients 1 vertebral body, in 10 patients 2 vertebral bodies, and in 9 patients 3 vertebral bodies were resected. After a mean 15-month follow-up …


Some Variations In The Formation Of The Brachialplexus In Infants*, Ahmet Uzun, Sai̇t Bi̇lgi̇ç Jan 1999

Some Variations In The Formation Of The Brachialplexus In Infants*, Ahmet Uzun, Sai̇t Bi̇lgi̇ç

Turkish Journal of Medical Sciences

The anatomical variations of the brachial plexus in human have clinical significance to surgeons, radiologists and anatomists. We studied some variations in the formation of 130 brachial plexuses in sixty-five infant cadavers (34 males, 31 females; aged 1-7 days). The brachial plexus consisted of the 5 th , 6 th , 7 th , and 8 th cervical spinal nerves and 1 st thoracic spinal nerve (69.23%). We found that among the 130 plexuses, 30.77% also received a contribution from C4 (Fig.1, A ) . The variations in the formation of brachial plexuses were classified into three groups. Group 1 …