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Articles 41401 - 41430 of 45190

Full-Text Articles in Medicine and Health Sciences

Plasma Resistin And Leptin Levels In Overweight And Lean Patients With Rheumatoid Arthritis, Nai̇me Canoruç, Ebru Kale, Ayşe Di̇cle Turhanoğlu, Şehmus Özmen, Ceyla Ogün, Abdurrahman Kaplan Jan 2009

Plasma Resistin And Leptin Levels In Overweight And Lean Patients With Rheumatoid Arthritis, Nai̇me Canoruç, Ebru Kale, Ayşe Di̇cle Turhanoğlu, Şehmus Özmen, Ceyla Ogün, Abdurrahman Kaplan

Turkish Journal of Medical Sciences

Aim: Adipocytokines are now considered important players in the etiopathogenesis of numerous metabolic and inflammatory disorders. However, plasma leptin and resistin levels in rheumatoid arthritis (RA) are still unclear. We aimed to investigate the plasma levels of leptin and resistin in patients with rheumatoid arthritis and to compare them with controls. Materials and Methods: Consecutive 52 patients with RA were compared with 52 control subjects in terms of mean leptin and resistin levels. Results: Patients with RA showed considerably higher plasma levels of leptin (34.3 ± 27.9 vs. 11.1 ± 4.1) and resistin (4.8 ± 0.7 vs. 4.0 ± 1.3) …

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Isolated Fungal Sinusitis Of The Sphenoid Sinus, Ayşe İri̇z, Muharrem Dağli, Hali̇t Akmansu, Özge Han, Bengi̇ Arslan, Adi̇l Eryilmaz Jan 2009

Isolated Fungal Sinusitis Of The Sphenoid Sinus, Ayşe İri̇z, Muharrem Dağli, Hali̇t Akmansu, Özge Han, Bengi̇ Arslan, Adi̇l Eryilmaz

Turkish Journal of Medical Sciences

Isolated fungal sphenoid sinusitis is a rare entity. Fungal sinusitis is mostly seen in immunocompromised patients and is characterized by invasive progression. We describe a immunologically competent patient with isolated aspergillosis in her sphenoid sinus.

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A Rare Cause Of Neonatal Hypocalcemia: Malignant Infantile Osteopetrosis, Hakan Uzun, Ebru Yilmaz Keski̇n, Dursun Ali̇ Şenses, Ayhan Erdem, Bünyami̇n Di̇ki̇ci̇, Kenan Kocabay Jan 2009

A Rare Cause Of Neonatal Hypocalcemia: Malignant Infantile Osteopetrosis, Hakan Uzun, Ebru Yilmaz Keski̇n, Dursun Ali̇ Şenses, Ayhan Erdem, Bünyami̇n Di̇ki̇ci̇, Kenan Kocabay

Turkish Journal of Medical Sciences

Malignant infantile osteopetrosis (MIOP) is a rare inherited bone disease characterized by reduced or dysregulated activity of osteoclasts, which results in generalized osteosclerosis. This leads to abnormal bone marrow cavity formation and to the clinical signs and symptoms of bone marrow failure and nerve compression. Symptoms related to early or late hypocalcemia may appear as the first presentation of MIOP in a newborn. We present a 14-day-old boy with neonatal hypocalcaemia due to MIOP.

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A Case Of Common Variable Immunodeficiency Disease And Thyroid Amyloidosis, Di̇lek Soysal, Ebru Türkkan, Volkan Karakuş, Erhan Tatar, Özlem Yersal Kabayeği̇t, Arzu Avci Jan 2009

A Case Of Common Variable Immunodeficiency Disease And Thyroid Amyloidosis, Di̇lek Soysal, Ebru Türkkan, Volkan Karakuş, Erhan Tatar, Özlem Yersal Kabayeği̇t, Arzu Avci

Turkish Journal of Medical Sciences

A 37-year-old male patient with fever, mild respiratory distress, diffuse goiter, and hepatosplenomegaly was admitted to our hospital. Clinical and laboratory findings showed that he had recurrent respiratory tract infections-namely bronchiectasis-due to common variable immunodeficiency disease (CVID) and AA-type amyloid deposition in the thyroid gland. Although recurrent infections as a consequence of inadequate gammaglobulin (IVIG) substitution therapy are regarded as the main cause of the development of amyloidosis, amyloidosis in a patient with hypo/agammaglobulinemia is extremely rare. In this report we discuss the association of CVID and recurrent respiratory tract infections with secondary amyloidosis restricted to one organ, the thyroid …

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Disseminated Herpes Zoster Infection In A Patient With Lymphoma, Behi̇ce Kurtaran, Semra Paydaş, Aslihan Candevi̇r, Süheyla Kömür, Hasan Sali̇h Zeki̇ Aksu Jan 2009

Disseminated Herpes Zoster Infection In A Patient With Lymphoma, Behi̇ce Kurtaran, Semra Paydaş, Aslihan Candevi̇r, Süheyla Kömür, Hasan Sali̇h Zeki̇ Aksu

Turkish Journal of Medical Sciences

Immunosuppression facilitates varicella zoster virus (VZV) reactivation in immunocompromised patients. Atypical presentation such as disseminated disease of herpes zoster infection has been described in immunosuppressed patients. One of the best choices of therapy in herpes zoster infection is acyclovir, but long-term therapy may cause resistance to it. In this report a disseminated herpes zoster infection is described in a patient with T cell lymphoma after acyclovir/valacyclovir therapy. The infection was irresponsive to acyclovir and valacyclovir and we were unable to control the infection because it was not possible to obtain foscarnet and the patient died due to Staphylococcus epidermis sepsis.

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Primary Mucosal Desmoplastic Melanoma Of The Gingiva, Reşi̇t Doğan Köseoğlu, İbrahi̇m Aladağ, Engi̇n Sezer, Ni̇lüfer Özkan Jan 2009

Primary Mucosal Desmoplastic Melanoma Of The Gingiva, Reşi̇t Doğan Köseoğlu, İbrahi̇m Aladağ, Engi̇n Sezer, Ni̇lüfer Özkan

Turkish Journal of Medical Sciences

Desmoplastic melanoma (DM) is a very rare variant of malignant melanoma. Mucosal involvement in DM is exceedingly rare and the differential diagnosis is problematic for surgical pathologists. To the best of our knowledge only 16 cases of DM originating from mucosal surfaces of the oral cavity have been described in the literature. Herein we describe a 59-year-old male with primary DM of the oral mucosa and discuss the status of p53, caspase-3, and FasL (Fas ligand) in the pathogenesis of this rare disease.

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A Patient With Addison's Disease Whose Sixth Pregnancy Resulted In A Healthy Baby, Yusuf Aydin, Merve Yilmaz, Di̇lek Berker, İhsan Üstün, Tuncay Deli̇başi, Serdar Güler Jan 2009

A Patient With Addison's Disease Whose Sixth Pregnancy Resulted In A Healthy Baby, Yusuf Aydin, Merve Yilmaz, Di̇lek Berker, İhsan Üstün, Tuncay Deli̇başi, Serdar Güler

Turkish Journal of Medical Sciences

No abstract provided.

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Measurement Of Total Antioxidant Response In Colorectal Cancer Using A Novel Automated Method, Abdullah Özgönül, Nurten Aksoy, Fuat Di̇lmec, Ali̇ Uzunköy, Şahi̇n Aksoy Jan 2009

Measurement Of Total Antioxidant Response In Colorectal Cancer Using A Novel Automated Method, Abdullah Özgönül, Nurten Aksoy, Fuat Di̇lmec, Ali̇ Uzunköy, Şahi̇n Aksoy

Turkish Journal of Medical Sciences

Aim: The aim of this study was to compare the antioxidative status in patients with colorectal cancer and healthy controls, based on measurements made using a novel method. Materials and Methods: The study was conducted between 2005 and 2007, and included 30 patients with colorectal cancer and 30 healthy controls. To determine the antioxidative status of the patients and healthy controls, serum total antioxidant capacity was measured using a novel automated method. Blood samples were taken from the healthy controls and the patients. Results: Total serum antioxidant capacity was significantly lower in colorectal cancer patients than in healthy persons (P < 0.023). Conclusions: Patients with colorectal cancer are exposed to oxidative stress, which may have a role in the pathogenesis of the disease. The novel automated method used in this study was developed in our laboratory, and is feasible and fully automated; therefore, it may be useful for evaluating oxidative-antioxidative balance in patients with colorectal cancer.

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The Role Of Magnetic Resonance Imaging In The Prediction Of The Neurodevelopmental Outcome Of Acute Bilirubin Encephalopathy In Newborns, Mustafa Mansur Tatli, Ahmet Karadağ, Ender Ödemi̇ş, Sümeyye Sarraoğlu, Mehmet Yörübulut Jan 2009

The Role Of Magnetic Resonance Imaging In The Prediction Of The Neurodevelopmental Outcome Of Acute Bilirubin Encephalopathy In Newborns, Mustafa Mansur Tatli, Ahmet Karadağ, Ender Ödemi̇ş, Sümeyye Sarraoğlu, Mehmet Yörübulut

Turkish Journal of Medical Sciences

Aim: Magnetic resonance imaging (MRI) is widely used in the diagnosis of acute bilirubin encephalopathy, but the relationship between MRI findings and neurodevelopmental outcome in newborns with acute bilirubin encephalopathy remains unclear. The aim of this study was to investigate the relationship between acute bilirubin encephalopathy, MRI findings, and neurodevelopmental outcome. Materials and Methods: The study included 13 infants with acute bilirubin encephalopathy. MRI was performed at 11-30 days of age. Infants were evaluated using the Denver Developmental Screening Test at 3 and 6 months of age. Results: Four of the 13 infants developed well. Five infants had abnormal MRI …

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The Effect Of Anterior Nasal Packing With Airway Tubes On Pulmonary Function Following Septoplasty*, Hani̇fi̇ Kurtaran, Nebi̇l Ark, Fati̇h Sadikoğlu, K. Şeri̇fe Uğur, Türker Yilmaz, Zeki̇ Yildirim, Davut Aktaş Jan 2009

The Effect Of Anterior Nasal Packing With Airway Tubes On Pulmonary Function Following Septoplasty*, Hani̇fi̇ Kurtaran, Nebi̇l Ark, Fati̇h Sadikoğlu, K. Şeri̇fe Uğur, Türker Yilmaz, Zeki̇ Yildirim, Davut Aktaş

Turkish Journal of Medical Sciences

Aim: To investigate the effects of nasal packing with airway tubes on pulmonary function following septoplasty. Materials and methods: Fifty patients who were operated for nasal septal deviation between 2006 and 2008 were included in our study. Nasal packs with airway tubes were used for all patients following septoplasty. Pulmonary function tests and PO2 measurements with pulse oximetry were performed preoperatively and in the second postoperative day just before removal of the nasal pack. Forced Vital Capacity (FVC), Forced Expiratory Volume in 1 Second (FEV_1), FEV_1/FVC (FEV_1%), Forced Expiratory Flow (FEF_{25-75}%), and PO2 values were compared. Results: The mean age …

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Annexin A2, A7, And A11 Expression In Head And Neck Squamous Cell Carcinoma*, Sema Hücümenoğlu, Berrak Gümüşkaya, Murat Alper, Bülent Öcal, Erdem Karabulut Jan 2009

Annexin A2, A7, And A11 Expression In Head And Neck Squamous Cell Carcinoma*, Sema Hücümenoğlu, Berrak Gümüşkaya, Murat Alper, Bülent Öcal, Erdem Karabulut

Turkish Journal of Medical Sciences

Aim: To investigate annexin A2 (ANXA2), annexin A7 (ANXA7), and annexin A11 (ANXA11) expression in head and neck squamous cell carcinoma (HNSCC). Although overexpression of ANXA2 has been reported in HNSCC, there are no studies on ANXA7 or ANXA11 in the same region. Materials and Methods: ANXA2, ANXA7, and ANXA11 were immunohistochemically studied in paraffin-embedded sections obtained from 43 patients with HNSCC. Results: ANXA2 and ANXA11 expression was more intense in the tumor areas in HNSCC (P = 0 for ANXA2, P = 0.05 for ANXA11). Both the tumors and normal mucosae showed membranous staining for ANXA7 and ANXA2, while …

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Radiological And Pathological Correlation In Patients With Bronchioloalveolar Lung Carcinoma, Serpi̇l Öcal, Gülnur Önde Üçoluk, Belgi̇n Samurkaşoğlu, Funda Demi̇rağ, İlker Eti̇kan, Peli̇n Bayazit Jan 2009

Radiological And Pathological Correlation In Patients With Bronchioloalveolar Lung Carcinoma, Serpi̇l Öcal, Gülnur Önde Üçoluk, Belgi̇n Samurkaşoğlu, Funda Demi̇rağ, İlker Eti̇kan, Peli̇n Bayazit

Turkish Journal of Medical Sciences

Aim: To assess the correlation between pathological and radiological findings in patients with pure bronchioloalveolar carcinoma (BAC). Materials and Methods: We retrospectively evaluated the pathological and radiological findings in patients with pure BAC. Results: We reviewed the case records, pathological specimens, and computer files of 26 patients with a pathologic diagnosis of pure BAC during a 3-year period. There was a statistically significant relationship between pathological and radiological findings (X^2 = 15.143, P = 0.004). There was a correlation between mucinous pathology and diffuse pattern, as well as between non-mucinous pathology and solitary nodule/mass/cavitation. A statistically significant relationship between lymphocytic …

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Evaluation Of Lower Urinary System Symptoms And Neurogenic Bladder In Children With Cerebral Palsy: Relationships With The Severity Of Cerebral Palsy And Mental Status, Si̇bel Ünsal, Canan Çulha, Hakan Tunç, Murat Kurt, Sumru Özel, Ali̇ Atan Jan 2009

Evaluation Of Lower Urinary System Symptoms And Neurogenic Bladder In Children With Cerebral Palsy: Relationships With The Severity Of Cerebral Palsy And Mental Status, Si̇bel Ünsal, Canan Çulha, Hakan Tunç, Murat Kurt, Sumru Özel, Ali̇ Atan

Turkish Journal of Medical Sciences

Aim: This study aimed to evaluate lower urinary system symptoms, to determine bladder type in children with cerebral palsy (CP), and to determine the relationship between bladder type, and the severity of CP and mental status of the children. Materials and Methods: The study included 41 children with CP. Subjects were first asked to provide information concerning lower urinary system symptoms. Urodynamic examination was performed in 41 children with CP. The severity of CP was determined according to the Gross Motor Functional Classification System (GMFCS). The Stanford-Binet Intelligence Scale was used to determine intelligence quotients (IQ). After urodynamic examination, subjects …

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Body Fat, Dyslipidemia, Blood Pressure And The Effects Of Smoking In Germans And Turks, Günay Can, Peter Schwandt, Altan Onat, Gülay Hergenç, Gerda-Maria Haas Jan 2009

Body Fat, Dyslipidemia, Blood Pressure And The Effects Of Smoking In Germans And Turks, Günay Can, Peter Schwandt, Altan Onat, Gülay Hergenç, Gerda-Maria Haas

Turkish Journal of Medical Sciences

Aim: Determining the difference regarding obesity in German and Turkish adults. Materials and Methods: This study examined a cross-section of adults aged 30-79 years old. Age-adjustment was uniformly provided for comparisons. Results: Among 3055 Germans and 2925 Turks, Turkish women had significantly higher markers of (abdominal) obesity than German women, while waist circumference (WC) was similar among males. Blood pressure (BP), concentrations of total, LDL-cholesterol, and apolipoprotein B were significantly higher among Germans, whereas Turks had markedly higher fasting triglycerides and lower HDL-cholesterol. Unlike Germans, the current trend of smoking among Turks correlates with lower WC and lower systolic BP …

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Clinical Evaluation Of 625 Lacunar Syndrome Patients, Kavian Ghandehari, Zahra Izadi Mood Jan 2009

Clinical Evaluation Of 625 Lacunar Syndrome Patients, Kavian Ghandehari, Zahra Izadi Mood

Turkish Journal of Medical Sciences

Aim: Lacunar syndromes consist of a group of characteristic clinical presentations that are usually compatible with a small deep infarct. Validation of these syndromes could help neurologists predict the prognosis and type of cerebrovascular disease. Materials and Methods: Consecutive stroke patients on 2 Iranian stroke registries compiled between 2001 and 2007 were enrolled in this prospective validation study. Lacunar syndromes were defined as pure motor, pure sensory, mixed sensory motor, ataxic hemiparesis, dysarthria clumsy hand, and atypical subtypes. All of the patients with ischemic stroke had at least one brain CT scan performed 48 h after stroke. Patients whose CT …

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Ureteroscopic Management Of Distal Ureteral Stones In Children: Holmium: Yag Laser Vs. Pneumatic Lithotripsy, Turgut Yapanoğlu, Hasan Riza Aydin, Yilmaz Aksoy, İsa Özbey Jan 2009

Ureteroscopic Management Of Distal Ureteral Stones In Children: Holmium: Yag Laser Vs. Pneumatic Lithotripsy, Turgut Yapanoğlu, Hasan Riza Aydin, Yilmaz Aksoy, İsa Özbey

Turkish Journal of Medical Sciences

Aim: In this retrospective study, we aimed to compare the treatment results of pneumatic and holmium laser-assisted ureteroscopy in managing distal ureteral calculi in children. Materials and methods: The study group included a total of 36 children (23 boys, 13 girls) who underwent ureteroscopy between June 1998 and April 2008 due to distal ureteral calculi. Pneumatic lithotripsy was performed in 11 children and holmium:YAG laser lithotripsy in 25. Results: Their ages ranged from 18 months to 14 years (mean: 8.5 ± 3.5 years). The overall success rate for the holmium:YAG laser lithotripsy (100%) was higher than that of pneumatic lithotripsy …

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Increased P Wave Dispersion In Hypothyroidism: A Sign Of Risk Of Atrial Fibrillation, Ramazan Akdemi̇r, Nesli̇han Ebru Eryaşar, Kudret Çeli̇k, Aşkin Güngüneş, Hakan Ci̇nemre, Cemi̇l Bi̇li̇r, Nermi̇n Akdemi̇r, Harun Kiliç Jan 2009

Increased P Wave Dispersion In Hypothyroidism: A Sign Of Risk Of Atrial Fibrillation, Ramazan Akdemi̇r, Nesli̇han Ebru Eryaşar, Kudret Çeli̇k, Aşkin Güngüneş, Hakan Ci̇nemre, Cemi̇l Bi̇li̇r, Nermi̇n Akdemi̇r, Harun Kiliç

Turkish Journal of Medical Sciences

Aim: As in hyperthyroidism, cardiac arrhythmias can be seen in hypothyroidism. In this study, we measured P wave dispersion among hypothyroid patients to evaluate atrial fibrillation risk. Methods: 75 patients who received first time diagnosis of hypothyroidism and 40 normal control patients were included in this study. Each patient had echocardiographic and electrocardiographic studies were carried out. Groups were compared for statistically significant difference in P wave dispersion, minimum P wave duration and maximum P wave duration. Results: The groups were similar in echocardiographic and electrocardiograpic features. P wave dispersion was significantly higher in the hypothyroid group compared to normal …

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Cefoperazone-Sulbactam Plus Amikacin Empirical Therapy For Febrile Neutropenia In Children With Cancer, İbrahi̇m Bayram, Fati̇h Erbey, Derya Alabaz, Sema Yilmaz, Ati̇la Tanyeli̇ Jan 2009

Cefoperazone-Sulbactam Plus Amikacin Empirical Therapy For Febrile Neutropenia In Children With Cancer, İbrahi̇m Bayram, Fati̇h Erbey, Derya Alabaz, Sema Yilmaz, Ati̇la Tanyeli̇

Turkish Journal of Medical Sciences

Aim: To determine the efficacy and safety of cefoperazone-sulbactam combined with amikacin in the treatment of febrile neutropenia in children with cancer. Materials and Methods: The study included 20 cancer cases with 26 febrile neutropenia (FEN) episodes. Patient selection criteria were defined according to the guidelines issued by the Infectious Disease Society of America (IDSA). Results: Patients diagnosed with acute leukemia (58%) and solid tumors (42%) were recorded. Twelve (46.2%) of the primary disease cases were refractory. The number of infection episodes identified microbiologically and clinically was 10 (38.5%) and 12 (46.1%), respectively. Fever of unknown origin was observed in …

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Cognitive Impairment Among Type-2 Diabetic Subjects And Its Relationship With Long-Term Complications, Oğuz Teki̇n, Serdar Çukur, Remzi̇ Karadağ, Ayşe Tunca, Olgun Göktaş, Adem Özkara, Bünyami̇n Işik, Sevsen Cebeci̇, Ramazan Yi̇ği̇toğlu Jan 2009

Cognitive Impairment Among Type-2 Diabetic Subjects And Its Relationship With Long-Term Complications, Oğuz Teki̇n, Serdar Çukur, Remzi̇ Karadağ, Ayşe Tunca, Olgun Göktaş, Adem Özkara, Bünyami̇n Işik, Sevsen Cebeci̇, Ramazan Yi̇ği̇toğlu

Turkish Journal of Medical Sciences

Aim: Studies about relationships between diabetes mellitus, diabetic complications, and cognitive functions have been initiative factors for this study. We evaluated various relations between procedure of the disease, diabetic complications, and cognitive functions among diabetic subjects. Materials and methods: Type-2 diabetic patients were evaluated for their disease status, complications, and cognitive functions (by Mini Mental State Examination (MMSE) test). We compared MMSE results of the patients with the control group. Results: We evaluated 75 patients with type-2 diabetes mellitus and 49 control subjects. Orientation (P = 0.006), attention and calculation (P = 0.002), and total (P < 0.001) scores of the control group were significantly greater compared to the diabetic group. We observed negative correlation between the length of disease and cognitive functions within the diabetic group. Recall scores of the diabetic subjects with 6 and less HBAIC levels were significantly greater than those with 6.1 and greater levels (P = 0.049). We observed negative relations between registration scores and retinopathy, but not between orientation and total scores and hypertension among diabetic subjects. Conclusion: Type-2 diabetes mellitus may destroy cognitive function. Length of disease, high serum HBAIC levels, hypertension, and retinopathy are significant additional risk factors. We conclude that cognitive function assessment should be routine procedure in the management of type-2 diabetes mellitus.

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Cut-Off Value Of D-Dimer In Pulmonary Thromboembolism And Pneumonia, Ayşegül Karalezli̇, H. Canan Hasanoğlu, Selda Kaya, Eli̇f Babaoğlu, Z. Ci̇bali̇ Açikgöz, Asi̇ye Kanbay, Derya Öztuna Jan 2009

Cut-Off Value Of D-Dimer In Pulmonary Thromboembolism And Pneumonia, Ayşegül Karalezli̇, H. Canan Hasanoğlu, Selda Kaya, Eli̇f Babaoğlu, Z. Ci̇bali̇ Açikgöz, Asi̇ye Kanbay, Derya Öztuna

Turkish Journal of Medical Sciences

Aim: The differential diagnosis of pulmonary thromboembolism (PTE) and pneumonia remains difficult in emergency rooms. High D-dimer levels in the pneumonia may be misdiagnosed as PTE on the basis of similar clinical, radiological, and laboratory findings. Since D-dimer elevation may also be seen in pneumonia cases, the comparison of D-dimer values in patients diagnosed as pneumonia and PTE, in order to determine a cut-off value between the 2 diseases, was aimed in this study. Materials and methods: Patients in the community acquired pneumonia (CAP) group were classified according to the American Thoracic Society (ATS) 2001 criteria. Groups III and IV …

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Does Employment Status Influence Obesity Prevalence Among Females? A Comparative Study From Ankara, Turkey, Di̇lek Aslan, Zeynep Altin, Necmi̇ye Beydağ, Celi̇le Hati̇poğlu Jan 2009

Does Employment Status Influence Obesity Prevalence Among Females? A Comparative Study From Ankara, Turkey, Di̇lek Aslan, Zeynep Altin, Necmi̇ye Beydağ, Celi̇le Hati̇poğlu

Turkish Journal of Medical Sciences

Aim: In this study, we aimed to compare the nutritional habits and obesity status of employed and not-employed (i.e. homemakers) women from an urban population in Ankara between April 2 and 17, 2007. Materials and methods: Employed females (107) were amongst Keçiören (a district of Ankara) municipal employees, and homemakers were selected among the residents of the catchment area of a primary health care unit (PHCU) within the same district. The 2 groups (employed and homemakers) were high school and university graduates and were similar to each other in terms of education and age. The World Health Organization defines "overweight" …

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The Effect Of Experimentally Induced Carbon Dioxide Pneumoperitoneum On Intra-Abdominal And Intra-Esophageal Ph, Tutku Soyer, Tolga Reşat Aydos, Zuhal Aktuna, Oğuzhan Korkut, Gökhan Osmanoğlu, Öymen Hançerli̇oğullari, Murat Çakmak Jan 2009

The Effect Of Experimentally Induced Carbon Dioxide Pneumoperitoneum On Intra-Abdominal And Intra-Esophageal Ph, Tutku Soyer, Tolga Reşat Aydos, Zuhal Aktuna, Oğuzhan Korkut, Gökhan Osmanoğlu, Öymen Hançerli̇oğullari, Murat Çakmak

Turkish Journal of Medical Sciences

Aim: An experimental study was performed to evaluate the effect of CO_2 pneumoperitoneum on intra-abdominal (IA) and intra-esophageal (IE) pH. Material and methods: The study included 18 Wistar rats. In the control group (n = 6) a pH catheter was inserted into the peritoneal cavity via a left upper quadrant incision and another catheter was inserted into the lower esophagus via the oral route. Pre- and post-insufflation IA and IE pH were recorded every 5 min for 1 h. In the experimental groups, in addition to pH catheters, a 16-G catheter was inserted into the abdomen above the umbilicus. In …

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Etofenamate And Anastomoses Of The Colon In Rats, Aydin İnan, Önder Sürgi̇t, Meral Şen, Ayhan Akpinar, Mi̇kdat Bozer Jan 2009

Etofenamate And Anastomoses Of The Colon In Rats, Aydin İnan, Önder Sürgi̇t, Meral Şen, Ayhan Akpinar, Mi̇kdat Bozer

Turkish Journal of Medical Sciences

Aim: Non-steroidal anti-inflammatory drugs have been used for many years due to their analgesic and anti-inflammatory properties. They have also been used for postoperative analgesia. We aimed to study the effects of etofenamate, a non-steroidal anti-inflammatory drug, on the healing of colonic anastomoses in rats. Materials and methods: Sprague-Dawley rats were used in this study. Resection and anastomosis were performed on the distal colon. The etofenamate group received 30 mg/kg etofenamate and the control group received 0.1 mL of 0.9% NaCl intramuscularly daily. Bursting pressures of anastomoses and hydroxyproline levels of perianastomotic tissues were determined on days 3 and 7. …

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Clinical And Pathological Features Of Nodular Gastritis In Adults, İbrahi̇m Koral Önal, Cenk Sökmensüer, Eda Demi̇r Önal, Osman Ersoy, Özgür Yeni̇ova, Musa Aydinli, Özlem Yönem, Özgür Harmanci, Yusuf Bayraktar, Fi̇gen Batman Jan 2009

Clinical And Pathological Features Of Nodular Gastritis In Adults, İbrahi̇m Koral Önal, Cenk Sökmensüer, Eda Demi̇r Önal, Osman Ersoy, Özgür Yeni̇ova, Musa Aydinli, Özlem Yönem, Özgür Harmanci, Yusuf Bayraktar, Fi̇gen Batman

Turkish Journal of Medical Sciences

Aim: Data on antral nodularity in adults are sparse. Although the association of nodular gastritis with Helicobacter pylori infection is well known, its potential as a premalignant lesion and its association with other gastroduodenal diseases are questionable. Materials and methods: The medical records of the patients between 2003 and 2006 were retrospectively reviewed to analyze their demographics, clinical characteristics, and endoscopic and pathological features. Results: Of 9949 adult patients who underwent endoscopy, 185 (1.86%) were diagnosed with nodular gastritis, 167 (90%) of whom had dyspepsia. The presence of Helicobacter pylori was demonstrated in 65.4% (121/185). There were 16 cases (8.7%) …

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An Analysis Of Adult Patients With Pulmonary And Extrapulmonary Tuberculosis*, Aygün Öztop, İpek Ünsal, Türkan Günay, Vi̇ldan Avkan Oğuz, Riza Çakmak Jan 2009

An Analysis Of Adult Patients With Pulmonary And Extrapulmonary Tuberculosis*, Aygün Öztop, İpek Ünsal, Türkan Günay, Vi̇ldan Avkan Oğuz, Riza Çakmak

Turkish Journal of Medical Sciences

Aim: In this study, it was planned to compare the features of pulmonary and extra-pulmonary tuberculosis patients over age 15 years. Materials and methods: We compared 360 newly diagnosed pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) patients who were treated and followed up in Kahramanlar Tuberculosis Dispensary between 2000 and 2003, and were older than 15 years of age. The medical records of both patient groups were investigated in terms of age, sex, accompanying diseases, contact history and means of diagnosis. Results: The data were compared statistically between the 2 groups. Of these patients 78.1% were diagnosed with PTB while …

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The Effects Of Adding Tramadol To Ropivacaine On Axillary Brachial Plexus Blockade In Uremic Patients*, Bayazit Di̇kmen, Mehmet Gamli, Eyüp Horasanli, Di̇lşen Örnek, Melekşah Pekel, Aydin Selçuk Jan 2009

The Effects Of Adding Tramadol To Ropivacaine On Axillary Brachial Plexus Blockade In Uremic Patients*, Bayazit Di̇kmen, Mehmet Gamli, Eyüp Horasanli, Di̇lşen Örnek, Melekşah Pekel, Aydin Selçuk

Turkish Journal of Medical Sciences

Aim: To evaluate the effect of tramadol added to ropivacaine on quality of anesthesia, onset of sensory and motor blockade, duration of sensory and motor blockade, and first analgesic request time for axillary brachial plexus block in uremic patients. Materials and methods: After institutional approval and informed consent had been obtained, 45 ASA III uremic patients (age range 30-80) scheduled for arteriovenous fistula surgery were included in the study. Patients were randomly allocated into 2 groups. Axillary block was performed with a peripheral nerve stimulator by multiple injection technique. Patients in Group R (n = 23) received 38 mL of …

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The Efficacy Of Quantitative Fluorescent-Polymerase Chain Reaction (Qf-Pcr) In The Diagnosis Of Prenatal Aneuploidy, Serpi̇l Aydoğmuş, Hüseyi̇n Levent Keski̇n, Semra Baykal Gökçe, Ayşe Fi̇li̇z Avşar, Emi̇ne Çelen Jan 2009

The Efficacy Of Quantitative Fluorescent-Polymerase Chain Reaction (Qf-Pcr) In The Diagnosis Of Prenatal Aneuploidy, Serpi̇l Aydoğmuş, Hüseyi̇n Levent Keski̇n, Semra Baykal Gökçe, Ayşe Fi̇li̇z Avşar, Emi̇ne Çelen

Turkish Journal of Medical Sciences

Aim: To investigate the efficacy of quantitative fluorescent-polymerase chain reaction (QF-PCR) in the diagnosis of aneuploidy. Materials and methods: The study included 40 pregnant women considered to be at high risk, based on positive trisomy 21 screening results, that underwent amniocentesis for karyotyping to detect chromosomal anomalies. In amniotic fluid aneuploidy detection was carried out by both standard karyotyping and the QF-PCR method, and the results obtained with both methods were compared. In order to determine the efficacy of QF-PCR, its sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated. Results: Of the 40 patients’ results …

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Endoscopic Polypectomy: Outcomes Of 467 Cases In 20 Years, S. Selçuk Atamanalp, Fuat Şentürk, Nesri̇n Gürsan, Gürkan Öztürk, Abdul Meci̇t Kantarci, M. İlhan Yildirgan, Mahmut Başoğlu Jan 2009

Endoscopic Polypectomy: Outcomes Of 467 Cases In 20 Years, S. Selçuk Atamanalp, Fuat Şentürk, Nesri̇n Gürsan, Gürkan Öztürk, Abdul Meci̇t Kantarci, M. İlhan Yildirgan, Mahmut Başoğlu

Turkish Journal of Medical Sciences

Aim: Endoscopic polypectomy has an important place in the treatment of polyps—the preliminary lesions of colorectal cancers. This study aimed to discuss the outcomes of endoscopic polypectomy in 467 patients for 692 polyps over the course of 20 years. Materials and methods: The records of 692 endoscopic polypectomies performed in 467 patients between July 1988 and July 2008 were retrospectively evaluated. Results: Patient age ranged from 3 to 85 years (mean: 50.6 years), and 302 of the 467 (64.7%) patients were male. Polypectomy was performed for 692 polyps (mean: 1.5; range: 1-12). The most common polyp location was the rectum …

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An Abnormal Digital Rectal Examination Is An Independent Predictor Of High Radical Prostatectomy Gleason’S Score ( ≥7) In Patients With Clinically Localized Prostate Cancer, Özgür Uğurlu, Mesut Çeti̇nkaya, Cüneyt Özden, Ç. Volkan Özteki̇n, A. Özgür Akdemi̇r, Ali̇ Memi̇ş, Mehmet Yariş Jan 2009

An Abnormal Digital Rectal Examination Is An Independent Predictor Of High Radical Prostatectomy Gleason’S Score ( ≥7) In Patients With Clinically Localized Prostate Cancer, Özgür Uğurlu, Mesut Çeti̇nkaya, Cüneyt Özden, Ç. Volkan Özteki̇n, A. Özgür Akdemi̇r, Ali̇ Memi̇ş, Mehmet Yariş

Turkish Journal of Medical Sciences

Aim: The aim of this study was to investigate the importance of digital rectal examination (DRE), serum total prostate specific antigen (PSA), percent free PSA (fPSA%), and PSA density (PSAD) in the prediction of high radical prostatectomy Gleason’s scores (GSs) ≥ 7 in patients with clinically localized prostate cancer. Materials and methods: Two hundred twenty-five patients who underwent radical prostatectomy for clinically localized prostate cancer were included in the study. The patients were grouped with respect to their radical prostatectomy GSs: group 1 including the patients with GSs < 6 (n = 170) and group 2 including the ones with GSs ≥ 7 (n = 55). The groups were compared with respect to potential predictors of a high GS, which were patient age, gland volume (Vp) obtained by transrectal ultrasound, DRE, PSA, fPSA%, and PSAD. Results: The mean age, PSA, fPSA%, and PSAD values of groups 1 and 2 were 65.23 ± 7.7 and 65.05 ± 7.1 years, 11.20 ± 9.2 and 11.09 ± 6.8 ng/mL, 16.2 ± 8.6 and 15.5 ± 8.1, and 0.25 ± 0.20 and 0.28 ± 0.18 ng/mL/cc, respectively. The groups were similar with respect to mean age, PSA, fPSA%, and PSAD (P > 0.05 for all). Mean prostate volume of patients in group 2 was …

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Reference Value For The Alad Enzyme Activity Ratio In Men Based On The Improvement Of Each Analytical Step Of The Colorimetric Method And The Active/Non-Active Lead Concept, Mustafa Gültepe, Hüseyi̇n Kayadi̇bi̇, Burhanetti̇n Bolat Jan 2009

Reference Value For The Alad Enzyme Activity Ratio In Men Based On The Improvement Of Each Analytical Step Of The Colorimetric Method And The Active/Non-Active Lead Concept, Mustafa Gültepe, Hüseyi̇n Kayadi̇bi̇, Burhanetti̇n Bolat

Turkish Journal of Medical Sciences

Aim: The ALAD enzyme activity ratio, which is highly sensitive to and specific for lead inhibition, can be used to diagnose lead-exposed individuals, but a reference value for it has not yet been established. Therefore, we aimed to establish a reference value for the ALAD activity ratio by improving each analytical step of the colorimetric method described by Mitchell et al. Materials and methods: Activators, pH, hemolyzing agents, and Ehrlich’s reagent were evaluated to obtain the optimal conditions for the restoration of lead-inhibited ALAD enzyme activity. Results: ZnCl2 and DTT were the preferred activators, the pH of sodium phosphate buffer …

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