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Full-Text Articles in Medicine and Health Sciences

The Prognostic Value Of Histological Grade In The Outcome Of Patients With Invasive Breast Cancer, Gül Dağlar, Yunus Nadi̇ Yüksek, Ahmet Uğur Gözalan, Tanju Tütüncü, Yeşi̇m Güngör, Nuri̇ Aydin Kama Jan 2010

The Prognostic Value Of Histological Grade In The Outcome Of Patients With Invasive Breast Cancer, Gül Dağlar, Yunus Nadi̇ Yüksek, Ahmet Uğur Gözalan, Tanju Tütüncü, Yeşi̇m Güngör, Nuri̇ Aydin Kama

Turkish Journal of Medical Sciences

Prognostic factors are useful for the prediction of survival in breast cancer patients. According to many studies, tumor size and lymph node stage are the most powerful predictors of tumor behavior. The aim of the present study was to investigate the prognostic value of tumor histological grade. Materials and methods: The study included 214 operable breast cancer patients treated at the same institution that were evaluated to determine the prognostic value of tumor histological grade. Clinico-histopathological features of the patients were also evaluated for overall survival (OS) and disease-free survival (DFS). Results: Tumor histological grade was an independent factor in …

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Can [F-18] Fluorodeoxyglucose Positron Emission Tomography Replace Sentinel Lymph Node Biopsy For The Detection Of Axillary Metastases In Patients With Early-Stage Breast Cancer?*, Semi̇h Görgülü, Mehmet Fati̇h Can, Oğuz Hançerli̇oğullari, Nuri̇ Arslan, Erkan Öztürk, Emel Öztürk, Müjdat Balkan, Turgut Tufan Jan 2010

Can [F-18] Fluorodeoxyglucose Positron Emission Tomography Replace Sentinel Lymph Node Biopsy For The Detection Of Axillary Metastases In Patients With Early-Stage Breast Cancer?*, Semi̇h Görgülü, Mehmet Fati̇h Can, Oğuz Hançerli̇oğullari, Nuri̇ Arslan, Erkan Öztürk, Emel Öztürk, Müjdat Balkan, Turgut Tufan

Turkish Journal of Medical Sciences

To investigate the value of fluorodeoxyglucose positron emission tomography (FDG-PET) in detecting axillary involvement, and to compare its accuracy with sentinel lymph node biopsy (SLNB) in patients with clinically early-stage breast cancer. Materials and methods: Twenty-eight female patients with histologically-confirmed T1-2 breast cancer who were scheduled to have SLNB were included in the study. FDG-PET images were obtained 1-7 days prior to surgery with an intravenous injection of 370 MBq of FDG, while plasma glucose levels were maintained below 120 mg/dL. All the images were interpreted by 2 independent nuclear medicine specialists, who were blinded to the histological diagnoses. SLNB …

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Do Uroflowmetric Findings Change By Treatment Of Urinary Tract Infection In Girls With Dysfunctional Voiding?, Emrah Şenel, Hüseyi̇n Tuğrul Ti̇ryaki̇, Fati̇h Akbiyik, Hali̇l Faruk Atayurt Jan 2010

Do Uroflowmetric Findings Change By Treatment Of Urinary Tract Infection In Girls With Dysfunctional Voiding?, Emrah Şenel, Hüseyi̇n Tuğrul Ti̇ryaki̇, Fati̇h Akbiyik, Hali̇l Faruk Atayurt

Turkish Journal of Medical Sciences

The goal of the study was to evaluate the efficiency of repeated uroflowmetry study in girls who present with dysfunctional voiding with normal radiologic evaluation. Materials and methods: Twenty five children (25 girls with a mean age of 8.9 years) with recurrent urinary tract infection (UTI) and dysfunctional voiding who have normal radiologic evaluation were prospectively evaluated by uroflowmetry tests. Uroflowmetry study was repeated after the UTI treatment in asymptomatic period. Results: Mean urine volume was 254.31 ± 199.49 cc and the mean micturition time was 25.22 ± 15.43 s at the first uroflowmetry. Prolonged micturition time was noted in …

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Comparison Of Remifentanil, Alfentanil, And Fentanil Co-Administered With Propofol To Facilitate Laryngeal Mask Insertion, Ali̇ Sizlan, Uğur Göktaş, Ceyda Özhan, Mehmet Özgür Özhan, Mehmet Emi̇n Orhan, Ercan Kurt Jan 2010

Comparison Of Remifentanil, Alfentanil, And Fentanil Co-Administered With Propofol To Facilitate Laryngeal Mask Insertion, Ali̇ Sizlan, Uğur Göktaş, Ceyda Özhan, Mehmet Özgür Özhan, Mehmet Emi̇n Orhan, Ercan Kurt

Turkish Journal of Medical Sciences

To compare the efficacy of different doses of fentanil, remifentanil, and alfentanil co-administered with propofol in patients undergoing minor surgery. Materials and methods: This double-blind, multi-centered, placebo-controlled study was conducted in 2 medical centers. One hundred forty-one ASA class I and II adult patients aged 18-65 years were included in the study. Patients received i.v. 1 µg kg^{-1} fentanil (group F, n = 33), 10 µg kg^{-1} alfentanil (group A, n = 33), 0.5 µg kg^{-1} remifentanil (group R, n = 36), or saline (control group, n = 39) co-administered with propofol 2.5 mg kg^{-1} without additives over 30 s. …

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Single Shot “3-In-1” Femoral Nerve Blockade With 0.25% Or 0.375% Levobupivacaine Provides Similar Postoperative Analgesia For Total Knee Replacement, Alpaslan Apan, Fi̇li̇z Sari, Alp Burak Ekmekçi̇ Jan 2010

Single Shot “3-In-1” Femoral Nerve Blockade With 0.25% Or 0.375% Levobupivacaine Provides Similar Postoperative Analgesia For Total Knee Replacement, Alpaslan Apan, Fi̇li̇z Sari, Alp Burak Ekmekçi̇

Turkish Journal of Medical Sciences

To compare postoperative analgesia provided by single shot "3-in-1" femoral nerve blockade using 0.25% or 0.375% levobupivacaine in preceding with spinal anesthesia for unilateral total knee replacement surgery. Materials and methods: Forty consenting patients undergoing unilateral total knee arthroplasty were included in this prospective randomized study. Spinal anesthesia was achieved with 15 mg plain bupivacaine at the L3-4 or L4-5 interspace. After resolution of the spinal anesthesia, patients were randomized into 2 groups: "3-in-1" femoral nerve blocks were performed using 30 mL of 0.25% levobupivacaine (Group 1, n = 20) or 0.375% levobupivacaine (Group 2, n = 20). Pain was …

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A Comparison Of The Treatment Of Ddh In The Older Children By Femoral Shortening With A) Acetabular Shelf And B) Innominate Osteotomy Plus Shelf, Meti̇n Doğan, Savaş Ağaoğlu, Durmuş Ali̇ Öçgüder, Mahmut Uğurlu, Rahmi̇ Yavuz Önem, Mustafa Aksoy, Murat Bozkurt Jan 2010

A Comparison Of The Treatment Of Ddh In The Older Children By Femoral Shortening With A) Acetabular Shelf And B) Innominate Osteotomy Plus Shelf, Meti̇n Doğan, Savaş Ağaoğlu, Durmuş Ali̇ Öçgüder, Mahmut Uğurlu, Rahmi̇ Yavuz Önem, Mustafa Aksoy, Murat Bozkurt

Turkish Journal of Medical Sciences

To examine the surgical outcome of 2 different techniques used in the treatment of developmental dislocation of the hip with delayed diagnosis. Materials and methods: The patients were divided into 2 groups based on the technique applied: 21 hips of 18 patients were included in Group 1 and 20 hips of 16 patients were included in Group 2. Initially, all the patients were subjected to femoral osteotomy, shortening, varization and derotation. In Group 1, additionally extra-articular grafting was performed for acetabulum and in Group 2, acetabular osteotomy and extraarticular grafting were performed. The mean age of Group 1 was 8 …

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Suitable Empiric Antibiotic Therapy Saves Life In Nosocomial Pneumonia Caused By Stenotrophomonas Maltophilia, Gürdal Yilmaz, Savaş Özsu, İfti̇har Köksal, Tevfi̇k Özlü Jan 2010

Suitable Empiric Antibiotic Therapy Saves Life In Nosocomial Pneumonia Caused By Stenotrophomonas Maltophilia, Gürdal Yilmaz, Savaş Özsu, İfti̇har Köksal, Tevfi̇k Özlü

Turkish Journal of Medical Sciences

Stenotrophomonas maltophilia is a nosocomial pathogen of increasing importance. Empiric antibiotic therapy for S. maltophilia infection is difficult because the microorganism is resistant to a number of agents typically used for health care associated infections, thus potentially increasing mortality. This study investigates 23 nosocomial pneumonia cases caused by S. maltophilia, the antibacterial sensitivity of the bacterium and the effect on mortality of suitable empiric therapy. Materials and methods: Twenty-three patients with nosocomial pneumonia caused by S. maltophilia between January 2000 and December 2006 at the Karadeniz Technical University Hospital were retrospectively investigated. Results: Suitable empiric therapy was used with 12 …

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The Relationship Between Daily Caffeine Consumption And Withdrawal Symptoms: A Questionnaire-Based Study, Nermi̇n Küçer Jan 2010

The Relationship Between Daily Caffeine Consumption And Withdrawal Symptoms: A Questionnaire-Based Study, Nermi̇n Küçer

Turkish Journal of Medical Sciences

To estimate daily caffeine intake among a group of university students at the Kocaeli Vocational School of Health Services in Turkey, and to determine the relationship between daily caffeine consumption and withdrawal symptoms. Materials and methods: This survey study was conducted using a questionnaire that was administered to 156 university students (129 females, 27 males) at the Kocaeli Vocational School of Health Services in Kocaeli, Turkey. The quantity of caffeine-containing products consumed was recorded on a daily basis, depending on the dietary habits of the consumer. The t test for differences between 2 proportions (using the normal approximation) was used …

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Nitric Oxide And Trace Metals In Relation To Haemoglobin F Concentration In Nigerian Sickle Cell Disease Patients, John Ayodele Olaniyi, Olatubosun Ganiyu Arinola Jan 2010

Nitric Oxide And Trace Metals In Relation To Haemoglobin F Concentration In Nigerian Sickle Cell Disease Patients, John Ayodele Olaniyi, Olatubosun Ganiyu Arinola

Turkish Journal of Medical Sciences

Sickle cell disease (SCD) is an inherited haemoglobin (Hb) disorder associated with vaso-occlusive events, oxidative stress, high energy demand, and endothelial dysfunction. The endothelium plays a central role in the regulation of vascular homeostasis by releasing nitric oxide (NO) among other factors. Therefore, the objective of this study was to measure plasma levels of NO, trace metals, and HbF in SCD patients. Materials and methods: Plasma levels of NO, Zn, Mg, Mn, Se, Cu, Fe, Haemoglobin F (HbF) were measured in 59 steady state SCD patients referred to the Department of Haematology, University College Hospital, Ibadan, Nigeria and 35 age/sex …

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Tetanus In An Intensive Care Unit Of A Turkish Hospital: Patient Analysis Of A 6-Year Period, Behi̇ce Kurtaran, Emre Karakoç, Aslihan Candevi̇r, Süheyla Kömür, Ayşe Seza İnal, Fi̇li̇z Ki̇bar, Yeşi̇m Taşova, Neşe Saltoğlu, Hasan Sali̇h Zeki̇ Aksu Jan 2010

Tetanus In An Intensive Care Unit Of A Turkish Hospital: Patient Analysis Of A 6-Year Period, Behi̇ce Kurtaran, Emre Karakoç, Aslihan Candevi̇r, Süheyla Kömür, Ayşe Seza İnal, Fi̇li̇z Ki̇bar, Yeşi̇m Taşova, Neşe Saltoğlu, Hasan Sali̇h Zeki̇ Aksu

Turkish Journal of Medical Sciences

To retrospectively evaluate the clinical features of patients admitted to the medical intensive care unit (ICU) of our hospital between January 2001 and May 2007 due to tetanus. Materials and methods: Patient vaccination history, incubation period, nosocomial infections, noninfectious conditions, mortality, and length of stay in the ICU and hospital were documented. Results: Fifteen tetanus patients were admitted during the 6-year period. Mean age of the patients (9 male, 6 female) was 60 ± 13 years. Median length of stay was 42 days (range: 30-77 days) for survivors and 7 days (range: 1-59 days) for non-survivors. Mortality was consequent to …

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Abnormal Hemoglobins Associated With The Beta-Globin Gene In Antalya Province, Turkey, İbrahi̇m Keser, Aki̇f Yeşi̇li̇pek, Duran Canatan, Güven Lüleci̇ Jan 2010

Abnormal Hemoglobins Associated With The Beta-Globin Gene In Antalya Province, Turkey, İbrahi̇m Keser, Aki̇f Yeşi̇li̇pek, Duran Canatan, Güven Lüleci̇

Turkish Journal of Medical Sciences

Abnormal hemoglobins are the most common hemoglobinopathies after beta-thalassemia in the world. More than 40 abnormal hemoglobin variants have been reported in the Turkish population. Therefore, it is one of the target areas for carrier screening. In our study, we aimed to screen the abnormal hemoglobins that cause clinical thalassemia in the Antalya population. Materials and methods: The present study identified the abnormal hemoglobins associated with the beta-globin gene using different molecular genetic techniques following high performance liquid chromatography (HPLC) results. We studied 972 postnatal and 361 prenatal cases (total: 1333 cases, 2666 chromosomes) with the disorder from 1998 up …

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Asymptomatic Carriage Of Bacteria In Food Workers In Nilüfer District, Bursa, Turkey*, Kayihan Pala, Cüneyt Özakin, Nalan Akiş, Melda Sinirtaş, Suna Gedi̇koğlu, Hamdi̇ Ayteki̇n Jan 2010

Asymptomatic Carriage Of Bacteria In Food Workers In Nilüfer District, Bursa, Turkey*, Kayihan Pala, Cüneyt Özakin, Nalan Akiş, Melda Sinirtaş, Suna Gedi̇koğlu, Hamdi̇ Ayteki̇n

Turkish Journal of Medical Sciences

This study was carried out in order to determine the nasal carriage of Staphylococcus aureus and the faecal carriage of Salmonella spp., Shigella spp., Yersinia enterocolitica, Listeria monocytogenes, and Escherichia coli O157:H7 in food industry workers. Materials and methods: During the study, face to face interviews were conducted with the workers and 9-item questionnaires regarding demographic information, working time, and periodical medical examinations were administered. In the study nasal swab specimens of 1115 individuals and faecal specimens of 1061 individuals were bacteriologically investigated. Results: The nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) was found to be significantly more common in …

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Four Cases Of Myotonia Congenita In A Turkish Family*, Recep Aygül, Gökhan Özdemi̇r, Di̇lcan Kotan Jan 2010

Four Cases Of Myotonia Congenita In A Turkish Family*, Recep Aygül, Gökhan Özdemi̇r, Di̇lcan Kotan

Turkish Journal of Medical Sciences

Myotonia congenita is a rare muscular disorder with autosomal dominant or autosomal recessive inheritance, and is characterized by painless myotonia. A 44-year-old mother presented at our clinic with a son and a daughter, all sharing the same complaints of difficulty in relaxing their hands and beginning to walk, and spasms during chewing. The family had also another 16-year-old daughter, but she had no such complaints. The mother reported that her father and 2 sisters had the same disease, but that her brother was healthy. Their pedigree analysis revealed that the disease was present for 3 generations and had an autosomal …

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Cancer And Ovarian Tissue Cryopreservation, Yavuz Emre Şükür, Batuhan Özmen, Murat Sönmezer Jan 2010

Cancer And Ovarian Tissue Cryopreservation, Yavuz Emre Şükür, Batuhan Özmen, Murat Sönmezer

Turkish Journal of Medical Sciences

Although ovarian tissue cryopreservation is still accepted as an experimental procedure, it has recently become an increasingly resorted technique in highly specialized in vitro fertilization (IVF) clinics. Its indications include many childhood cancers, breast cancer, some autoimmune diseases, hematopoietic stem cell transplantation, and pelvic radiation therapy due to solid tumors. The chemotherapeutics and radiation therapy may diminish ovarian reserve and cause premature ovarian failure. It currently seems as the only option for fertility preservation in children where ovulation induction is ethically not acceptable, and for those when cytotoxic therapy is urgent. There are 2 main methods for transplantation of frozen-thawed …

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Cd10 Expression In Urothelial Bladder Carcinomas: Staining Patterns And Relationship With Pathologic Parameters*, Ni̇lüfer Onak Kandemi̇r, Burak Bahadir, Banu Doğan Gün, Gamze Yurdakan, Ni̇met Karadayi, Şükrü Oğuz Özdamar Jan 2010

Cd10 Expression In Urothelial Bladder Carcinomas: Staining Patterns And Relationship With Pathologic Parameters*, Ni̇lüfer Onak Kandemi̇r, Burak Bahadir, Banu Doğan Gün, Gamze Yurdakan, Ni̇met Karadayi, Şükrü Oğuz Özdamar

Turkish Journal of Medical Sciences

CD10 is a cell surface metalloprotease that inactivates various bioactive neuropeptides. CD10 has been suggested as a useful prognostic marker for urothelial carcinoma, but there are only a few studies of CD10 in urothelial tumors and they have shown varying results. The aims of this study were to investigate the expression of CD10 in urothelial bladder carcinomas and to clarify its association with pathologic parameters. Materials and methods: A total of 50 urothelial bladder carcinomas were selected from archival material. All cases were reevaluated histopathologically and graded according to the WHO/ISUP 1998 classification. The TNM system was used for their …

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Small-For-Gestational-Age Newborns Need A Special Fluid Therapy Strategy, Alparslan Tonbul, Cüneyt Tayman, Ahmet Karadağ, Hali̇se Akça, Nurdan Uras, Mustafa Mansur Tatli Jan 2010

Small-For-Gestational-Age Newborns Need A Special Fluid Therapy Strategy, Alparslan Tonbul, Cüneyt Tayman, Ahmet Karadağ, Hali̇se Akça, Nurdan Uras, Mustafa Mansur Tatli

Turkish Journal of Medical Sciences

To determine the fluid requirement of small-for-gestational-age (SGA) newborns and to compare them with that of appropriate for gestational age (AGA) newborns in the first 5 days of life. Materials and methods: The present study was conducted from January 2007 to August 2007, including newborns with a gestation age of 32-40 weeks, with respiratory problems, feeding problems, and prematurity, and required intravenous fluid for at least 3 days. Two study groups were established: SGA (group 1) and AGA (group 2) according to the Lubchenco scale. All newborns were cared at an ambient humidity of 40% in an incubator and received …

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Serum Nitric Oxide And Peroxynitrite Levels In Adult Sero-Positive Rheumatoid Arthritis Treated With Disease Modifying Antirheumatic Drugs: A Preliminary Report, Marwan S.M. Al-Nimer, Samir Abdul-Hassan Al-Obaidi, Khalid S. Al-Dulaimi Jan 2010

Serum Nitric Oxide And Peroxynitrite Levels In Adult Sero-Positive Rheumatoid Arthritis Treated With Disease Modifying Antirheumatic Drugs: A Preliminary Report, Marwan S.M. Al-Nimer, Samir Abdul-Hassan Al-Obaidi, Khalid S. Al-Dulaimi

Turkish Journal of Medical Sciences

The contribution of inducible nitric oxide synthase (iNOS) to oxidative/nitrative stress is well documented in inflamed joints. Nitric oxide stimulates the synthesis of proinflammatory mediators and cytotoxic molecules with a pivotal role in apoptosis at the joint of rheumatoid arthritis. This study aimed to assess the serum levels of nitric oxide and peroxynitrite in sero positive rheumatoid patients treated with disease modifying antirheumatic drugs. Materials and methods: Sixteen known patients with sero-positive rheumatoid arthritis fulfilling the criteria of the American College of Rheumatology and on disease modifying antirheumatic drugs were allocated from the consultant clinic of rheumatology at Al-Yarmouk Teaching …

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Histopathologic Changes In The Rabbit Submandibular Gland After 5-Fluorouracil Chemotherapy, Oktay Özel, Abdullah Ayçi̇çek, Fethullah Kenar, Fatma Aktepe, Ramazan Sargin, Mustafa Deni̇z Yilmaz, Fevzi̇ Sefa Dereköy Jan 2010

Histopathologic Changes In The Rabbit Submandibular Gland After 5-Fluorouracil Chemotherapy, Oktay Özel, Abdullah Ayçi̇çek, Fethullah Kenar, Fatma Aktepe, Ramazan Sargin, Mustafa Deni̇z Yilmaz, Fevzi̇ Sefa Dereköy

Turkish Journal of Medical Sciences

To determine the early-stage effects of 5-fluorouracil (5-FU) on the histology of the submandibular gland. Materials and methods: The study included 30 New Zealand rabbits. They were divided into 3 groups. No drugs were administered to group 1 (control group), and 5-FU was administered for 5 days to group 2 and for 10 days to group 3. Submandibular gland excision was then performed. Histopathological examination was performed with hematoxylin-eosin staining, apoptosis was determined based on TUNEL staining, and cell proliferation was examined using the PCNA antibody. Results: While no granular change was seen in group 1, granular change was observed …

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Serum Nonesterified Fatty Acids, Ghrelin, And Homocysteine Levels In Women With Polycystic Ovary Syndrome, İsmai̇l Temel, Önder Çeli̇k, Şeyma Hasçalik, Ni̇lüfer Çeli̇k, İbrahi̇m Şahi̇n, Süleyman Aydin Jan 2010

Serum Nonesterified Fatty Acids, Ghrelin, And Homocysteine Levels In Women With Polycystic Ovary Syndrome, İsmai̇l Temel, Önder Çeli̇k, Şeyma Hasçalik, Ni̇lüfer Çeli̇k, İbrahi̇m Şahi̇n, Süleyman Aydin

Turkish Journal of Medical Sciences

To investigate the possible relationship of serum levels of nonesterified fatty acids (NEFA), ghrelin, and homocysteine levels to metabolic and hormonal features in women with polycystic ovary syndrome (PCOS). Materials and methods: Thirty women with PCOS and 30 healthy women with similar age and body mass index (BMI) were recruited. Fasting serum NEFA, ghrelin, homocysteine, growth hormone (GH), cardiac troponin I, glucose, insulin, lipids, and homeostasis model assessment of insulin resistance (HOMA-IR) were measured. Results: Serum NEFA, homocysteine, insulin, HOMA-IR, cholesterol, and testosterone levels were significantly higher but in contrast ghrelin level was significantly lower in women with PCOS compared …

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Subclinical Hypothyroidism In Obese Turkish Adolescents: The Relationship With Anthropometry And Fatty Liver, Şami̇l Hizli, Nur Arslan, Ayhan Abaci, Benal Büyükgebi̇z Jan 2010

Subclinical Hypothyroidism In Obese Turkish Adolescents: The Relationship With Anthropometry And Fatty Liver, Şami̇l Hizli, Nur Arslan, Ayhan Abaci, Benal Büyükgebi̇z

Turkish Journal of Medical Sciences

To evaluate whether subclinical hypothyroidism (SH) is associated with anthropometry and fatty infiltration of liver in obese adolescents. Materials and methods: The adolescents attended with the complaint of obesity aged 11 to 15 years included in the study. Patients were diagnosed as obese adolescents with fatty liver. Age-, gender-, and body weight-matched obese adolescents without fatty liver seen during the same period served as controls. Clinical characteristics, laboratory parameters, and frequency of subclinical hypothyroidism (SH) of both groups were compared. Results: The study population included 218 adolescents with obesity. Of 218, 30 (13.7%) had fatty liver at ultrasonography (group 1) …

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Clinical Presentation Of Breast Tuberculosis In Eastern Anatolia, S. Selçuk Atamanalp, Cemal Gündoğdu, Pinar Polat, Gürkan Öztürk, Bülent Aydinli, Durkaya Ören, Mahmut Başoğlu, M. İlhan Yildirgan Jan 2010

Clinical Presentation Of Breast Tuberculosis In Eastern Anatolia, S. Selçuk Atamanalp, Cemal Gündoğdu, Pinar Polat, Gürkan Öztürk, Bülent Aydinli, Durkaya Ören, Mahmut Başoğlu, M. İlhan Yildirgan

Turkish Journal of Medical Sciences

Breast tuberculosis is a very rare disease of the breast. This report aimed to review our clinical experience of 20 years and 7 cases of breast tuberculosis. Materials and methods: The records of 7 patients with breast tuberculosis were reviewed retrospectively. Results: The surgical procedure applied for breast tuberculosis comprised 1.3% of all surgical procedures of breast surgery. The mean age of the breast tuberculosis patients was 36 years, and all of the patients were female. The mean symptom duration was 12.8 months. The most common symptoms were painful breast mass in all the patients, 2 (28.6%) of whom had …

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A Bacteriological Examination Of Urine Before And After Urodynamic Testing, Defne Gümüş, Yaşar Bağdatli Jan 2010

A Bacteriological Examination Of Urine Before And After Urodynamic Testing, Defne Gümüş, Yaşar Bağdatli

Turkish Journal of Medical Sciences

Urodynamic studies have been associated with an increased risk of bacteriuria and symptomatic urinary tract infection (UTI) because it is applied by invasive catheterization. In this study the value of antibiotic prophylaxis in decreasing the risk of bacteriuria and symptomatic UTI has been questioned in children. Materials and methods: Urine samples of 90 patients, who were taken before and after urodynamic testing in Cerrahpaşa Faculty of Medicine Videourodynamics Laboratory of Child Surgery Department, were cultured microbiologically to determine the presence of bacteriuria. Results: The rate of bacteriuria was found statistically higher in 50 patients under trimethoprim/sulphamethoxazole and 17 under nitrofurantoin …

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The Role Of Ultrasonographic Hepatic Artery Resistive Index In The Diagnosis Of Insulin Resistance In Obese Children With Non-Alcoholic Fatty Liver Disease, Şami̇l Hizli, Ali̇ Koçyi̇ği̇t, Nur Arslan, Sedat Alpaslan Tuncel, Fati̇h Demi̇rci̇oğlu, Handan Çakmakçi, Benal Büyükgebi̇z Jan 2010

The Role Of Ultrasonographic Hepatic Artery Resistive Index In The Diagnosis Of Insulin Resistance In Obese Children With Non-Alcoholic Fatty Liver Disease, Şami̇l Hizli, Ali̇ Koçyi̇ği̇t, Nur Arslan, Sedat Alpaslan Tuncel, Fati̇h Demi̇rci̇oğlu, Handan Çakmakçi, Benal Büyükgebi̇z

Turkish Journal of Medical Sciences

To determine the role of hepatic artery resistive index (HARI) measurement in the prediction of insulin resistance (IR) in obese children with nonalcoholic fatty liver disease (NAFLD). Materials and methods: A total of 64 obese subjects with NAFLD (13.5 ± 1.36 years of age, 34 male) and 32 age- and gender-matched control subjects (13.8 ± 1.24 years of age, 16 male) were enrolled in the study. All subjects underwent a physical examination, laboratory tests, and ultrasonographic and Doppler examinations of the liver. The homeostasis model assessment of IR (HOMA-IR) was used for the IR diagnosis. Results: Obese subjects with NAFLD …

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Effect Of Passive Smoking On The Development Of Chronic Obstructive Pulmonary Disease In Southeastern Turkey, Teki̇n Yildiz, Füsun Topçu, Yusuf Çeli̇k, Levent Akyildiz, Güngör Ateş, Di̇lek Durak Jan 2010

Effect Of Passive Smoking On The Development Of Chronic Obstructive Pulmonary Disease In Southeastern Turkey, Teki̇n Yildiz, Füsun Topçu, Yusuf Çeli̇k, Levent Akyildiz, Güngör Ateş, Di̇lek Durak

Turkish Journal of Medical Sciences

To determine the effect of passive smoking on the development of chronic obstructive pulmonary disease (COPD) among persons who spend a long time in cafes. Materials and methods: The study sample included 348 male smokers who were older than 40 years and spend a long time in cafes. The questions were derived from the European Coal and Steel Community (ECSC) questionnaire. We also inquired about the nature of cafe visits (hours/day, visits/week, visits/month). Results: COPD was found in 18.1% (63/348 subjects) of the smokers aged >=40 years. In these 63 subjects, based on spirometry results, the rate of mild and …

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Hospital-Acquired Pneumonia In Nonintensive Care Unit Wards, Meltem Avci, Onur Özgenç, Ayten Coşkuner, Berna Bozca, Levent Kidak, Gülşen Mermut, Mehmet Sezai̇ Taşbakan, Nesli̇han Genç, Gülşen Güloğlu, Alpay Ari Jan 2010

Hospital-Acquired Pneumonia In Nonintensive Care Unit Wards, Meltem Avci, Onur Özgenç, Ayten Coşkuner, Berna Bozca, Levent Kidak, Gülşen Mermut, Mehmet Sezai̇ Taşbakan, Nesli̇han Genç, Gülşen Güloğlu, Alpay Ari

Turkish Journal of Medical Sciences

To determine the incidence, risk factors, etiology, and antibiotic susceptibility of hospital-acquired pneumonia (HAP) in nonintensive care units (non-ICU) and nonintubated adult patients. Materials and methods: A prospective surveillance study was performed from January 2006 through December 2007 in the medical and surgical wards of the İzmir Teaching and Research Hospital. Results: During the study period, data on 57,133 patients with a total of 413,515 patient-days were analyzed. A total of 106 HAP episodes occurred in 99 patients. The infection rate per 100 patients and per 1000 patient-days was found to be 0.2% and 0.3%, respectively. HAP episodes were detected …

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Comparison Of The Effects Of Repeated Dose Treatments Of Lornoxicam And Meloxicam On Renal Functions In Rats, Başak Pehli̇van, Özgün Çuvaş, Hülya Başar, Fati̇h Bakir, Hüseyi̇n Üstün, Bayazit Di̇kmen Jan 2010

Comparison Of The Effects Of Repeated Dose Treatments Of Lornoxicam And Meloxicam On Renal Functions In Rats, Başak Pehli̇van, Özgün Çuvaş, Hülya Başar, Fati̇h Bakir, Hüseyi̇n Üstün, Bayazit Di̇kmen

Turkish Journal of Medical Sciences

We aimed to investigate the renal effects of meloxicam, a preferential cyclooxygenase-2 inhibitor nonsteroidal antiiflammatory drug, and lornoxicam, a nonspecific cyclooxygenase inhibitor, in rats. We wanted to test the hypothesis that preferential cyclooxygenase-2 inhibitors have a higher renal safety profile when compared with the nonspecific cyclooxygenase inhibitors. Materials and methods: Thirty healthy male Sprague-Dawley rats were included in the study. During the study period, 0.9% NaCl, 5.8 mg kg^{-1} meloxicam, or 1.3 mg kg^{-1} lornoxicam were given in 1 mL volumes once daily by the peritoneal route. On day 14, rats were placed in metabolic cages and their urine was …

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Protective Effect Of Selenium On Intussusception-Induced Ischemia/Reperfusion Intestinal Oxidative Injury In Rats*, Hülya Akman, Sali̇h Somuncu, Günnur Di̇kmen, Şebnem Ayva, Tutku Soyer, Paki̇ze Doğan, Murat Çakmak Jan 2010

Protective Effect Of Selenium On Intussusception-Induced Ischemia/Reperfusion Intestinal Oxidative Injury In Rats*, Hülya Akman, Sali̇h Somuncu, Günnur Di̇kmen, Şebnem Ayva, Tutku Soyer, Paki̇ze Doğan, Murat Çakmak

Turkish Journal of Medical Sciences

To evaluate the protective effect of selenium on intestinal ischemia-reperfusion injury due to intussusception. Materials and methods: Forty Wistar albino rats were allocated to 4 equal groups (n = 10). After anesthetization, 2 cm of intestinal segment, 20 cm proximal to the ileocecal valve, was removed in the control group (CG). In the intussusception group (ING), intussusception was performed 20 cm proximal to the ileocecal valve by pushing the proximal intestinal segment distally with a stylet, and 2 cm of intestinal segment was removed 4 h later. Intussusception was reduced and a 2 cm segment was removed after another 4 …

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Possible Role Of Toxoplasmosis In Patients With First-Episode Schizophrenia*, Mehmet Tanyüksel, Özcan Uzun, Engi̇n Araz, Özgür Koru, Cahi̇t Babür Jan 2010

Possible Role Of Toxoplasmosis In Patients With First-Episode Schizophrenia*, Mehmet Tanyüksel, Özcan Uzun, Engi̇n Araz, Özgür Koru, Cahi̇t Babür

Turkish Journal of Medical Sciences

To determine the possible relationship between toxoplasmosis and patients with first-episode schizophrenia (FES). Materials and methods: Seventy-three subjects with FES (15-54 years old; mean: 23.4 years) and 40 healthy individuals (20-54 years old; mean: 30.3 years) were enrolled in the study. Most of the FES patients (90.4%) and the control individuals (95.0%) were male. Specific IgG and IgM antibodies to Toxoplasma gondii were investigated by enzyme-linked immunosorbent assay (ELISA), and the total amount of antibodies was investigated with the Sabin-Feldman dye test (SFDT). Results: Compared to the control individuals, study subjects had significantly more toxoplasmosis-like symptoms and more cats in …

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Oxidative Predictors And Lipoproteins In Male Soccer Players, Faruk Yamaner Jan 2010

Oxidative Predictors And Lipoproteins In Male Soccer Players, Faruk Yamaner

Turkish Journal of Medical Sciences

To determine male soccer players’ lipoprotein levels, and their total antioxidant capacity, total oxidant status, oxidative stress index, and lipid hydroperoxide and lipoprotein levels after exercise. Materials and methods: The study group included 33 certificated male soccer players with an age range of 17-20 years and the control group included 53 healthy male volunteers with an age range of 18-20 years. Their total antioxidant capacity, total oxidant status, oxidative stress index, and lipid hydroperoxide and lipoprotein levels were analyzed and compared. Results: In the baseline, plasma levels, total oxidant statuses, oxidative stress indices, and lipid hydroperoxide levels were found of …

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Molecular Analyses Of Salmonella Serotype Typhi And Salmonella Serotype Paratyphi B Strains Isolated In Turkey, Istar Dolapçi, Bi̇rsel Erdem, Alper Tekeli̇, Ebru Us, Mehseti̇ Bayramova, Begüm Saran, Fi̇kret Şahi̇n Jan 2010

Molecular Analyses Of Salmonella Serotype Typhi And Salmonella Serotype Paratyphi B Strains Isolated In Turkey, Istar Dolapçi, Bi̇rsel Erdem, Alper Tekeli̇, Ebru Us, Mehseti̇ Bayramova, Begüm Saran, Fi̇kret Şahi̇n

Turkish Journal of Medical Sciences

To investigate the characteristics of Salmonella serotype Typhi and Salmonella serotype Paratyphi B, which still remain significant in Turkey. Materials and methods: Eighteen S. Typhi and 42 S. Paratyphi B strains isolated from clinical samples were investigated by plasmid profile analysis, enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR), and pulsed field gel electrophoresis (PFGE) methods. Results: Plasmid profile analysis showed that 10 out of 18 (56%) S. Typhi isolates harbored 1 to 3 plasmids, and 11 out of 42 (26.2%) S. Paratyphi B isolates harbored 1 to 4 plasmids. PFGE performed with restriction enzyme AvrII grouped both S. Typhi and …

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