Medicine and Health Sciences Commons^™

Dens Agenesis And Cervical Vertebral Malformation In A Labrador Retriever Puppy, Elisa Salas, Henry E. Cerny, Seth P. Harris

School of Veterinary and Biomedical Sciences: Faculty Publications

Cervical vertebral malformations can cause acute or progressive pain, paralysis, and potentially death. Herein we present a case report of dens agenesis; cervical vertebral malformations of C1, C2, C6, and C7; subluxation of C1 and C2 and C4 and C5; and associated degenerative myelopathy in a 5-month-old female Labrador Retriever puppy. We additionally review current knowledge regarding pathogenesis and treatment.

The Role Of Scavenger Receptor Class B Type I-Regulated Inducible Glucocorticoids In Sepsis, Junting Ai

Theses and Dissertations--Nutritional Sciences

Sepsis claims over 215,000 lives in the US annually. Inducible glucocorticoids (iGC) is produced during sepsis. However, the precise effects of iGC in sepsis remain unclear due to a lack of appropriate animal models. Glucocorticoid (GC) insufficiency is associated with a marked increase in mortality and occurs in 60% of severe septic patients. Yet the conclusion of GC therapy on septic patients is still controversial.

Scavenger receptor class B type I (SR-BI) in the adrenal mediates the selective uptake of cholesteryl ester from lipoproteins for GC synthesis. SR-BI-/- mice completely lack iGC during sepsis and are highly susceptible to septic …

Statistical Modeling Of Interfractional Tissue Deformation And Its Application In Radiation Therapy Planning, Douglas J. Vile

Theses and Dissertations

In radiation therapy, interfraction organ motion introduces a level of geometric uncertainty into the planning process. Plans, which are typically based upon a single instance of anatomy, must be robust against daily anatomical variations. For this problem, a model of the magnitude, direction, and likelihood of deformation is useful. In this thesis, principal component analysis (PCA) is used to statistically model the 3D organ motion for 19 prostate cancer patients, each with 8-13 fractional computed tomography (CT) images. Deformable image registration and the resultant displacement vector fields (DVFs) are used to quantify the interfraction systematic and random motion. By applying …

Cyclic Peptide-Capped Gold Nanoparticles For Enhanced Sirna Delivery, Amir Nasrolahi Shirazi, Karissa L. Paquin, Niall G. Howlett, Dindyal Mandal, Keykavous Parang

Pharmacy Faculty Articles and Research

Previously, we have reported the synthesis of a homochiral L-cyclic peptide [WR]5 and its use for delivery of anti-HIV drugs and biomolecules. A physical mixture of HAuCl4 and the peptide generated peptide-capped gold nanoparticles. Here, [WR]5 and [WR]5-AuNPs were tested for their efficiency to deliver a small interfering RNA molecule (siRNA) in human cervix adenocarcinoma (HeLa) cells. Flow cytometry investigation revealed that the intracellular uptake of a fluorescence-labeled non-targeting siRNA (200 nM) was enhanced in the presence of [WR]5 and [WR]5-AuNPs by 2- and 3.8-fold when compared with that of siRNA alone after 24 h incubation. Comparative toxicity results showed …

Altered Mucins (Muc) Trafficking In Benign And Malignant Conditions., Suhasini Joshi, Sushil Kumar, Amit Choudhury, Moorthy P. Ponnusamy, Surinder K. Batra

Journal Articles: Biochemistry & Molecular Biology

Mucins are high molecular weight O-glycoproteins that are predominantly expressed at the apical surface of epithelial cells and have wide range of functions. The functional diversity is attributed to their structure that comprises of a peptide chain with unique domains and multiple carbohydrate moieties added during posttranslational modifications. Tumor cells aberrantly overexpress mucins, and thereby promote proliferation, differentiation, motility, invasion and metastasis. Along with their aberrant expression, accumulating evidence suggest the critical role of altered subcellular localization of mucins under pathological conditions due to altered endocytic processes. The mislocalization of mucins and their interactions result in change in the density …

Evaluation Of Multiple Choice And Short Essay Question Items In Basic Medical Sciences, Mukhtiar Baig, Syeda Kauser Ali, Sobia Ali, Nighat Huda

Department of Continuing Professional Education

OBJECTIVES:

To evaluate Multiple Choice and Short Essay Question items in Basic Medical Sciences by determining item writing flaws (IWFs) of MCQs along with cognitive level of each item in both methods.

METHODS:

This analytical study evaluated the quality of the assessment tools used for the first batch in a newly established medical college in Karachi, Pakistan. First and sixth module assessment tools in Biochemistry during 2009-2010 were analyzed. Cognitive level of MCQs and SEQs, were noted and MCQ item writing flaws were also evaluated.

RESULTS:

A total of 36 SEQs and 150 MCQs of four items were analyzed. The …

Attachment Style And Perceived Social Support As Predictors Of Biopsychosocial Adjustment To Cancer, Ayşe Gül Yilmaz Özpolat, Tuğba Ayaz, Özlem Konağ, Asi̇ye Özkan

Turkish Journal of Medical Sciences

Social support is associated with a decrease in psychological symptoms and a better quality of life in cancer patients. The aim of this study was to investigate the role of attachment dimensions on social and psychological adjustment to cancer and to explore the social and psychological adjustments, and medical adherence, among patients. Materials and methods: The study was conducted with 68 cancer patients, between 18 and 74 years of age. The measures taken were the Demographic Information Form, Multidimensional Scale of Perceived Social Support (MSPSS), Experiences in Close Relationships-Revised (ECR-R), and Psychosocial Adjustment to Illness Scale (PAIS-SR). Results: The results …

Effects Of Short-Term Hyperglycemia On The Vasoconstriction Of The Aorta, Soner Dönmez, Osman Gökalp, Mustafa Doğan, Hüseyi̇n Vural, Barbaros Yi̇ği̇t

Turkish Journal of Medical Sciences

To investigate vasoconstrictor responses of healthy blood vessels to short-term hyperglycemic conditions such as postprandial hyperglycemia, gestational diabetes mellitus, and steroid-induced diabetes. Materials and methods: Female Wistar rat aorta rings were incubated in normal (11 mM) and high (22 mM and 44 mM) glucose concentrations for 4 h. Responses of vasoconstriction were measured in reaction to serotonin (10-5 M), phenylephrine (10-6 M), and KCl (60 mM) compared to the ambient condition, including different glucose concentrations. Results: While the responses of vasoconstriction to KCl were increased in the presence of Krebs' solution with high glucose, no statistically significant changes were observed …

Is The Combined Use Of Insulin Resistance Indices, Including Adipokines, More Reliable In Metabolic Syndrome?, Bi̇rgül Kural, Orhan Değer, Ci̇hangi̇r Erem, Fulya Balaban Yücesan, Rezzan Ali̇yazicioğlu, Yaşam Barlak

Turkish Journal of Medical Sciences

To determine the levels of adipokines (leptin, adiponectin, resistin, and visfatin) and the indices of insulin sensitivity/resistance, and to examine the relationship among them in patients with metabolic syndrome (MetS). Materials and methods: The study groups included 45 subjects with MetS (31 women/14 men), and 45 sex-and age-matched non-MetS healthy volunteers (31 women/14 men). The levels of adipokines were determined by enzyme-linked immunosorbent assay. Results: The levels of leptin and visfatin were significantly higher in the MetS than in the non-MetS subjects (P < 0.01). There was no difference in adiponectin levels in subjects with and without MetS (P = 0.052). Similarly, resistin did not show any statistically significant difference. A statistically significant positive correlation of leptin with insulin levels was observed, while negative correlations of visfatin levels with age, and resistin levels with the ratio of adiponectin to leptin, were found in the MetS (P < 0.05). The combination of adipokines, insulin resistance-sensitivity parameters, and MetS criteria parameters gave more significant differences than a single parameter. Conclusion: Since the parameters mentioned above might affect, interact with, and/or interfere with each other, the combinations of these parameters might give more reliable results to evaluate the insulin resistance/sensitivity in MetS patients.

Induction Of A Type I Interferon Signature In Normal Human Monocytes By Gadolinium-Based Contrast Agents: Comparison Of Linear And Macrocyclic Agents., Peter J. Wermuth, Sergio A. Jimenez

Jefferson Institute of Molecular Medicine Papers and Presentations

The gadolinium-based contrast agent (GdBCA) Omniscan activates human macrophages through Toll-like receptor (TLR)-4 and TLR-7 signalling. To explore the mechanisms responsible we compared the ability of linear and macrocyclic GdBCA to induce a type I interferon signature and a proinflammatory/profibrotic phenotype in normal human monocytes in vitro. Expression of genes associated with type I interferon signalling and inflammation and production of their corresponding proteins were determined. Both linear and macrocyclic GdBCA stimulated expression of multiple type I interferon-regulated genes and the expression of numerous chemokines, cytokines and growth factors in normal human peripheral blood monocytes. There was no correlation between …

Increased Incidence Of Asthma After Previous Infantile Rsv Bronchiolitis Infection, Ellen Adelia Doebler

Physician Assistant Scholarly Project Posters

• Respiratory Syncytial Virus (RSV) is a very common infection in children less than two years of age.

• Asthma is a common respiratory disease in childhood, which may cause frequent hospitalizations.

• The purpose of this study is to determine if infants previously diagnosed with RSV bronchiolitis have an increased incidence of asthma diagnosis compared to infants not diagnosed with RSV.

• The literature review examines correlation studies of both disease processes and explores incidence of asthma in patients previously diagnosed with Respiratory Syncytial Virus bronchiolitis.

• Individuals previously diagnosed with Respiratory Syncytial Virus bronchiolitis have a higher risk …

Electronic Prescribing And Its Implementation In The United States, Kate Englebert, Amber Porterfield, William K. Willis, Alberto Coustasse

Management Faculty Research

Introduction: Electronic prescribing (e-prescribing) is an important part of the nation’s push to create an electronically accessible national health system. E-prescribing allows providers to send prescriptions electronically to the pharmacy and can be stand-alone systems or part of an integrated electronic health record system.

Methodology: The methodology for this study was a literature review. Electronic databases accessed include EBSCOhost, PubMED, and Google Scholar. Additionally, government websites and a semi-structured interview were used. A total of 39 sources were referenced for the review.

Results: The results of the literature review demonstrated that e-prescribing reduces prescribing errors, increases efficiency, and helps save …

Influenza Hospitalizations In New York State 2007-2013 : Impact Of Vaccine And Antiviral Treatment Effectiveness In Reducing Severity Of Illness, Mary Dundas

Legacy Theses & Dissertations (2009 - 2024)

Background: Underlying medical conditions are known risk factors for increased severity of infectious diseases, including influenza. Although most studies on disease severity, underlying medical conditions, and prevention/treatment effectiveness occurred during the pandemic 2009-2010 season, data is also available for seasons when influenza virus B and influenza virus A subtypes pH1N1, seasonal H1N1, and H3N2 were circulating.

Comparison Of Intraarticular Bupivacaine And Levobupivacaine Injection In Rat Synovial Inflammation, Beki̇r Suat Kürkçüoğlu, Melahat Dönmez, Seher Altinel, Seda Banu Akinci, Fatma Saricaoğlu, Ülkü Aypar

Turkish Journal of Medical Sciences

Both bupivacaine and levobupivacaine are local anesthetics with strong analgesic efficacy that can be used intraarticularly. The aim of this study was to compare the effects of intraarticular bupivacaine and levobupivacaine injection on inflammation in articular cartilage and the synovium of the rat knee joint. Materials and methods: Twenty Sprague-Dawley rats were injected in the right knee joint with 0.2 mL of bupivacaine, while 0.2 mL of levobupivacaine was injected into the left knee joint. Groups of 5 were sacrificed on days 1, 7, 14, and 21 after bupivacaine and levobupivacaine administration and knee joints were examined for subintimal fibrosis, …

Effect Of Ginkgo Biloba On Brain Volume After Carotid Artery Occlusion In Rats: A Stereological And Histopathological Study, Zeynep Aktürk, Ersan Odaci, Ayşe İki̇nci̇, Orhan Baş, Si̇nan Canpolat, Serdar Çolakoğlu, Osman Fi̇kret Sönmez

Turkish Journal of Medical Sciences

This study investigated the effect of Ginkgo biloba (GB) on brain volume in cerebral ischemia induced by stopping carotid artery blood flow. Materials and methods: Twenty-four adult male rats were divided into 4 groups of 6 rats each. No procedure was performed on the control group. Ischemia was applied to the rats in the ischemia and ischemia + GB groups by clamping the arteria carotis communis for 30 min. The rats in the ischemia + GB group were given 100 mg/kg drops (Tebokan Fort Drop, Abdi İbrahim İlaç Sanayi A.Ş., Turkey) containing dry GB leaf extract orally, every day for …

Comparison Of Hippocampal Interleukin-6 Immunoreactivity After Exhaustive Exercise In Both Exercise-Trained And Untrained Rats, Lati̇fe Arzu Aral, Lamia Pinar, Güleser Göktaş, Elçi̇n Yaşar Deveden, Deni̇z Erdoğan

Turkish Journal of Medical Sciences

Exhaustive exercise is a strong stress factor and can impact cytokine production in the brain. Interleukin-6 (IL-6) is produced in greater amounts than any other cytokine in response to exercise, and its effects are closely related to both exercise duration and intensity. In this study, we measured the differences between the amount of IL-6 reactivity of the hippocampus after an exhaustive session of running in long-term exercise-trained and untrained rats. Materials and methods: The exercise-trained group ran on a treadmill for 12 weeks. Both groups were forced to run until exhaustion. Each group of rats was sacrificed immediately, 1 day, …

The Role Of Hepcidin And Its Related Genes (Bmp6, Gdf-15, And Hjv) In Rats Exposed To Ischemia And Reperfusion, Recep Dokuyucu, Tuncer Demi̇r, Önder Yumrutaş, Ayşe Bi̇nnur Erbağci, Mustafa Örkmez, Abdulkadi̇r Yasi̇r Bahar, Recep Bayraktar, İbrahi̇m Bozgeyi̇k, Davut Si̇nan Kaplan, Beyhan Cengi̇z, Cahi̇t Bağci

Turkish Journal of Medical Sciences

To determine the roles of hepcidin and its related genes in a renal ischemia/reperfusion model. Materials and methods: A total of 20 Wistar albino rats were equally divided into 2 groups: Group I was the control group and Group II was the ischemia and reperfusion (I/R) group (60 min of ischemia + 48 h of reperfusion). I/R was performed on the left kidneys of these rats and then the I/R-treated kidneys were removed. The levels of serum biochemical markers were evaluated after renal I/R. The expression levels of hepcidin-linked genes [growth differentiation factor 15 (GDF-15), bone morphogenetic protein 6 (BMP6), …

Asymmetric Dimethyl Arginine Levels In Chronic Hemodialysis Patients, Aydin Çi̇fci̇, Sali̇h İnal, Coşkun Kaya

Turkish Journal of Medical Sciences

To investigate serum asymmetric dimethyl arginine (ADMA) levels in maintenance hemodialysis (HD) patients and to assess their potential correlations with C-reactive protein (CRP), albumin, and cholesterol levels as the established cardiovascular and nutritional parameters. Materials and methods: Forty-nine patients on maintenance HD treatment and 22 healthy volunteers with similar age and sex characteristics were recruited into the study. Serum albumin, CRP, creatinine, calcium, phosphate, total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, hemoglobin, white blood cell counts, and serum ADMA levels were measured. Results: HD patients had significantly higher ADMA levels compared with healthy controls (0.51 ± 0.25 …

Migraine Prevalence, Disability, And Sociodemographic Properties In The Eastern Region Of Turkey: A Population-Based Door-To-Door Survey, Gökhan Özdemi̇r, Recep Aygül, Recep Demi̇r, Lütfi̇ Özel, Ayfer Erteki̇n, Hizir Ulvi̇

Turkish Journal of Medical Sciences

To determine the frequency of migraine in the eastern part of Turkey and its sociodemographic characteristics, impact on disability, and clinical aspects. Materials and methods: The study was conducted door-to-door in the eastern part of Turkey. Those who suffered from headaches were diagnosed with migraine as per the 2004 diagnosis criteria of the International Headache Society and its frequency was determined. Demographic data and Migraine Disability Assessment Scale (MIDAS) scores were recorded. Results: Of the individuals evaluated, 60.4% (883) suffered from headaches, of which 43.6% (637) were evaluated as nonmigraine and 16.8% (246) as migraine headaches. Migraine prevalence was detected …

Genotype Distribution Of Hepatitis C Virus In Khorasan Razavi Province, Iran, Reza Afshari, Hosein Nomani, Fatemeh Riyahi Zaniani, Maryam Sadat Nabavinia, Zohreh Mirbagheri, Mojtaba Meshkat, Sina Gerayli, Sina Rostami, Zahra Meshkat

Turkish Journal of Medical Sciences

Several types of the hepatitis C virus (HCV), with variations in different parts of the genome, have been isolated from different regions of the world. Based on heterogenic sequences in the isolated genome, HCV is classified into different genotypes and subtypes. Data on distribution of HCV genotypes in a certain region could be important to patient management. Therefore, this study was conducted to determine the distribution of HCV in Mashhad, Northeast Iran. Materials and methods: This cross-sectional study was conducted on 103 patients with HCV infections in Mashhad. Among the participants, at least 22 (21.4%) were intravenous drug users. HCV …

Transradial Approach In The Diagnosis And Treatment Of Coronary Artery Disease: A 2-Center Experience, Mustafa Yurtdaş, Yüksel Kaya, Edi̇p Gönüllü

Turkish Journal of Medical Sciences

To document the safety, success, and complications of transradial coronary procedures. Materials and methods: This retrospective study consisted of 427 patients who had undergone transradial coronary angiography and/or angioplasty between June 2010 and May 2012. The main outcome measures were the procedural safety, success rate, and complications associated with transradial interventions. Results: Procedural success rate was 93.2% (398/427), with cannulation time of 2.1 ± 1.4 min, diagnostic time of 5.6 ± 2.1 min, fluoroscopy time of 9.5 ± 6.6 min, and total procedure time of 47.1 ± 20.2 min. The main causes for unsuccessful procedures were failed radial puncture (11 …

Seasonal Variation And Risk Factors Associated With Surgical Site Infection Rate In Kano, Nigeria, Emmanuel Nwankwo, Stephen Edino

Turkish Journal of Medical Sciences

To evaluate the seasonal variations and risk factors associated with surgical site infection (SSI) rate in Kano. Materials and methods: A total of 5800 patients admitted for surgery, drawn from Aminu Kano Teaching Hospital and Murtala Mohammed Specialist Hospital, underwent different types of surgical procedures between January 2010 and December 2011. Out of those patients, 1463 confirmed infected cases were screened for bacterial and fungal infection by standard microbiological procedures. Questionnaires were administered after informed consent to ascertain patients' lifestyles. Medical histories were obtained from their case files. Results: Out of 5800 patients, 1463 were confirmed to be clinically infected, …

Age-Related Changes In Biomechanical Parameters Of The Cornea And Intraocular Pressure In A Healthy Turkish Population, Emi̇ne Şen, Kadri̇ye Ufuk Elgi̇n, Pinar Yüksekkaya, Mehmet Hakan Tirhiş, Fatma Nur Baran Aksakal, Mehmet Yasi̇n Teke, Faruk Öztürk

Turkish Journal of Medical Sciences

To investigate age-related changes in intraocular pressure (IOP) and biomechanical parameters of the cornea in healthy subjects. Materials and methods: There were 404 healthy subjects included prospectively in this study. The subjects were divided into 3 groups (Group 1: 93 subjects aged 60). Corneal compensated IOP (IOPcc), Goldmann correlated IOP (IOPg), corneal hysteresis (CH), and corneal resistance factor (CRF) were measured by the Ocular Response Analyzer. Results: When all the study groups were evaluated, a moderately significant negative correlation was found between age and CH and between age and CRF (Spearman's rho = -0.372 and -0.353, respectively; P < 0.0001 for both correlations). There were significant age-related differences among the 3 groups in terms of IOPg, CH, CRF, and central corneal thickness (P = 0.002, P = 0.000, P = 0.000, P = 0.006). There was no confirmation of any difference of IOPcc among the groups (P = 0.427). Conclusion: The mean values of IOPg, CH, and CRF were lower than the other parameters in Group 3 but no significant differences were determined in IOPcc values in the age groups.

Effects Of Some Of The Regional Turkish Fermented Foods And Medications On Respiratory Alcohol Levels, Cem Uysal, Mustafa Karapi̇rli̇, Mehmet Aki̇f İnanici

Turkish Journal of Medical Sciences

Alcohols are used in many areas like medicine and industry. They may be naturally found in some fruits and vegetables secondary to fermentation. According to the traffic law in Turkey, professional drivers are prohibited from driving while they are under the influence of alcohol; nonprofessional drivers are allowed to drive vehicles with a blood alcohol level of up to 50 mg/dL. The aim of this research is to determine whether or not consumed medicine or fermented, nonalcoholic beverages cause false positive results in breathalyzer tests. Materials and methods: In this research, we used nonalcoholic fermented foods and 6 medicines. After …

Normal M Mode Values In Healthy Turkish Children, Bülent Oran, Abdurrahman Sai̇d Bodur, Derya Arslan, Derya Çi̇men, Osman Güvenç

Turkish Journal of Medical Sciences

Evaluation of cardiac structures requires a large study group for accurate data on normal values. The aim of the study was to obtain normal M mode echocardiographic values in a substantial sample of healthy term neonates and children to develop centile charts. Materials and methods: Data were obtained over 2 years from a single center in Turkey, from 1200 healthy infants and children aged 1 day to 17 years. Using echocardiographic investigation, measurements were obtained of the following: left ventricular dimension at end diastole and end systole; thickness of interventricular septum and posterior wall of the left ventricle; aortic and …

Is The Diagnosis And Treatment Of Childhood Acute Bacterial Meningitis In Turkey Evidence-Based?, Özden Türel, Mustafa Bakir

Turkish Journal of Medical Sciences

Evidence-based guidance is likely to significantly improve patient care. We aimed to characterize the adequacy of standard diagnostic methods and treatment in children with acute bacterial meningitis (ABM) in Turkey. Materials and methods: We conducted a retrospective study among children 1 month to 5 years old hospitalized with ABM in İstanbul. The World Health Organization case definition and laboratory criteria were used for diagnosis. Results: Of the 283 cases, 250 were probable and 33 (11.2%) were confirmed as bacterial meningitis. The majority of patients (92%) were treated at 9 governmental hospitals and the remaining 21 at 2 university hospitals. Blood …

Association Between The Apelin Rs2235306 Gene Polymorphism And Metabolic Syndrome, Mohammad Hashemi, Hamzeh Rezaei, Ebrahim Eskandari-Nasab, Mahmoud Ali Kaykhaei, Mohsen Taheri

Turkish Journal of Medical Sciences

The rs2235306 of apelin polymorphism has been shown to be associated with fasting plasma glucose levels and hypertension. The present study aimed to investigate the impact of the apelin rs2235306 gene polymorphism on the risk of metabolic syndrome (MeS) in a sample of the Iranian population. Materials and methods: This population-based cross-sectional study was performed on 151 subjects with MeS and 149 without MeS, as defined by ATPIII criteria. Apelin rs2235306 polymorphism detection was done using the tetra amplification refractory mutation system-polymerase chain reaction. Because the apelin gene is located on the X chromosome, statistical analyses were conducted in a …

Endothelial Dysfunction And Insulin Resistance In Young Women With Polycystic Ovarian Syndrome, Mi̇ne Yavuz Taşlipinar, Nedret Kiliç, Ni̇lüfer Bayraktar, İsmai̇l Güler, Yasemi̇n Gülcan Kurt, Tayfun Göktaş, Mehmet Zeki̇ Taner, Mehmet Özdemi̇r Hi̇mmetoğlu, Hali̇l Yaman, Abdullah Taşlipinar

Turkish Journal of Medical Sciences

To evaluate whether there is a correlation between insulin resistance and nitric oxide-related endothelial dysfunction in patients with polycystic ovarian syndrome (PCOS). Materials and methods: The study was conducted with 25 young women with PCOS and 25 young healthy women, between 18 and 35 years of age. Plasma asymmetric dimethylarginine (ADMA) levels, serum nitric oxide (NO) levels, and homeostatic model assessment of insulin resistance (HOMA-IR) rates were measured in both the patient and control groups. Results: Plasma ADMA levels were significantly higher in PCOS patients than in the controls (P = 0.001). Serum NO levels were significantly lower in patients …

Pittsburgh Sleep Quality Index Scores And Their Relationship With Body Measurements In Late Menopause Patients, Ayli̇n Ayrim, Esra Aktepe Keski̇n, Duygu Özol

Turkish Journal of Medical Sciences

With an increase in life expectancy, women live about one-third of their lives in the postmenopausal period. Our aim was to investigate the findings regarding quality of sleep and sleep apnea in postmenopausal women and research the relationship between sleep complaints and body measurements. Materials and methods: The Pittsburgh Sleep Quality Index (PSQI) was administered to all participants and their height, weight, and neck circumferences were measured. Results: A total of 206 patients (mean age: 61.4 ± 8.8 years) were included. Their mean weight gain after menopause was 8.1 ± 12.8 kg, and their mean neck circumference and body mass …

Seroprevalences And Associated Risk Factors Of Hepatitis B And C In Adults, Mustafa Yildirim, Selma Çakir, Mehmet Faruk Geyi̇k, Davut Özdemi̇r, Ertuğrul Güçlü, Mehmet Çakir

Turkish Journal of Medical Sciences

Chronic hepatitis due to hepatitis B and hepatitis C virus infections is the most common cause of chronic liver disease. In this study we aimed to find out seroprevalences and associated risk factors of hepatitis B and C in adults in Düzce. Materials and methods: The sample of study was determined with a cluster-type sampling method. The study included 1321 people, consisting of 667 women and 654 men who were 18 years or older. A questionnaire about demographic information and risk factors was applied. Results: Seroprevalences of HBsAg, anti-HBs, and anti-HCV were 4.8%, 9.4%, and 0.7%, respectively. HBsAg seroprevalences were …