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Articles 121 - 137 of 137
Full-Text Articles in Medicine and Health Sciences
Effects Of Aqueous Garlic Extract On Oxidant/Antioxidant Status In 32d And 32dp210 Cell Lines, Aslihan Avci, Asuman Sunguroğlu, İmge B. Ergüder, Güvem Gümüş Akay, Erdi̇nç Devri̇m, Pinar Özkal Baydin, Nuray Varol, İlker Durak
Effects Of Aqueous Garlic Extract On Oxidant/Antioxidant Status In 32d And 32dp210 Cell Lines, Aslihan Avci, Asuman Sunguroğlu, İmge B. Ergüder, Güvem Gümüş Akay, Erdi̇nç Devri̇m, Pinar Özkal Baydin, Nuray Varol, İlker Durak
Turkish Journal of Medical Sciences
To investigate the possible effects of aqueous garlic extract on the oxidant/antioxidant status and apoptosis in 32D (wild type mouse myeloid cell = normal) and 32Dp210 (BCR-ABL fusion gene (+) mouse myeloid cell = Chronic Myelocytic Leukemia cells) cell lines. Materials and methods: Aqueous garlic extract (10% w/v) was added into the cell line media with 2 different final concentrations (0.4% and 1%). At 0 h and at 24, 48, and 72 h later, the oxidant (malondialdehyde (MDA) level, and xanthine oxidase (XO) enzyme activity) and antioxidant (superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) enzyme activities) parameters were …
Evaluation Of Oxidant/Antioxidant Status And Ecp Levels In Asthma, Ömer Emecen, Berri̇n Berçi̇k İnal, Füsun Erdenen, Murat Usta, Hale Aral, Güvenç Güvenen
Evaluation Of Oxidant/Antioxidant Status And Ecp Levels In Asthma, Ömer Emecen, Berri̇n Berçi̇k İnal, Füsun Erdenen, Murat Usta, Hale Aral, Güvenç Güvenen
Turkish Journal of Medical Sciences
Inflammatory and immune cells, such as eosinophils, macrophages, and neutrophils, generate more reactive oxygen species in patients with asthma than they do in healthy individuals, and oxygen radicals contribute to tissue injury in asthma. We aimed to measure total oxidant status (TOS) and antioxidant status (TAS) in order to assess oxidative and antioxidative capacity. Eosinophil cationic protein (ECP), total IgE, and eosinophils (%) were measured to evaluate the level of inflammation. Materials and methods: The study included 56 non-smoking asthma patients that were followed-up at the respiratory disease and allergy outpatient clinics, where they received ongoing treatment for 5 months …
Comparison Of In Vitro Cytotoxicity And Genotoxicity Of Mma-Based Polymeric Materials And Various Metallic Materials, Sultan Gülçe İz, Sai̇me İsmet Gürhan, Bi̇lge Hakan Şen, Tuğba Endoğan, Nesri̇n Hasirci
Comparison Of In Vitro Cytotoxicity And Genotoxicity Of Mma-Based Polymeric Materials And Various Metallic Materials, Sultan Gülçe İz, Sai̇me İsmet Gürhan, Bi̇lge Hakan Şen, Tuğba Endoğan, Nesri̇n Hasirci
Turkish Journal of Medical Sciences
To determine the in vitro cytotoxicity and genotoxicity of some polymeric and metallic implant materials used as base materials in dentistry, based on ISO (International Organization for Standardization) and OECD (Organization for Economic Co-Operation and Development) test protocols. Materials and methods: Three different acrylate-based polymeric materials were tested for their in vitro cytotoxicity and genotoxicity (polymethylmethacrylate microspheres [PMMA], a solid cement prepared by mixing PMMA with its monomer methylmethacrylate [PMMA+MMA], a solid cement prepared by mixing PMMA, MMA, and hydroxyapatite [PMMA+MMA+HA], as wells as 4 different metallic materials (titanium [Ti grade 4], nickel alloy 625 [Ni-625], stainless steel alloy 304L …
The Effect Of Caffeic Acid Phenethyl Ester On Bacterial Translocation And Intestinal Damage After Intestinal Obstruction, Cengi̇z Ara, Abuzer Di̇ri̇can, Seli̇m Erdoğan, Burhan Ateş, Di̇nçer Özgör, Fai̇k Tatli, M. Sai̇t Tekerekoğlu, Vedat Kirimlioğlu
The Effect Of Caffeic Acid Phenethyl Ester On Bacterial Translocation And Intestinal Damage After Intestinal Obstruction, Cengi̇z Ara, Abuzer Di̇ri̇can, Seli̇m Erdoğan, Burhan Ateş, Di̇nçer Özgör, Fai̇k Tatli, M. Sai̇t Tekerekoğlu, Vedat Kirimlioğlu
Turkish Journal of Medical Sciences
Intestinal obstruction (IO) induces bacterial translocation due to failure of the intestinal barrier function. Following bacterial overgrowth, its degradation products play a decisive role in the development of systemic septic complications. The aim of this study was to evaluate the effects of caffeic acid phenethyl ester (CAPE) on bacterial translocation and intestinal damage in an IO model in rats. Materials and methods: Complete IO was created in the distal ileum of rats by a single 4-0 silk suture. A total of 21 Wistar albino rats were randomized into 3 groups: Group 1, Sham (n = 7); Group 2, IO (n …
Dermatoglyphics As Markers Of Prenatal Disturbances In Schizophrenia: A Case-Control Study, Bi̇rsen Özyurt, Ahmet Songur, Mustafa Sarsilmaz, Ömer Akyol, Mustafa Namli, Reha Demi̇rel
Dermatoglyphics As Markers Of Prenatal Disturbances In Schizophrenia: A Case-Control Study, Bi̇rsen Özyurt, Ahmet Songur, Mustafa Sarsilmaz, Ömer Akyol, Mustafa Namli, Reha Demi̇rel
Turkish Journal of Medical Sciences
Several studies have reported the importance of dermatoglyphics as markers of a prenatal disturbance in patients with schizophrenia. Due to the fact that finger- and handprints are formed by the end of the second trimester, they may provide clues to disturbances in early development. The aim of this study was to determine specific dermatoglyphical frequencies in a sample of patients with schizophrenia and normal controls. Materials and methods: Fingerprints and palm prints were obtained from 45 schizophrenic patients as well as 45 healthy controls. The dermatoglyphic patterns on the fingers (total finger ridge count [TFRC]) and palms (a-b, b-c, and …
Evaluation Of Coping Strategies, Social Support, And Depressive Symptoms In Spouses Of Patients With Hematological Cancer, Safi̇ye Özkan, Yasemi̇n Kutlu
Evaluation Of Coping Strategies, Social Support, And Depressive Symptoms In Spouses Of Patients With Hematological Cancer, Safi̇ye Özkan, Yasemi̇n Kutlu
Turkish Journal of Medical Sciences
The purpose of this study was the evaluation of coping strategies, social support, and depressive symptoms in spouses of patients with hematological cancer. Materials and methods: A descriptive design was used in current study. The study was carried out at the hematology clinic of 2 university hospitals located in İstanbul. The convenience sample consisted of 150 spouses of patients who had hematological cancer. The data were collected through structured face-to-face interviews using a questionnaire form, the "Ways of Coping" Questionnaire, the Multidimensional Perceived Social Support Scale, and Beck Depression Inventory. Percentage t-tests and Pearson's product moment correlation were used to …
Reliability Of Self-Reported History In Predicting Immunity Against Measles, Rubella, Mumps, And Varicella Among Health Care Workers, Çi̇gdem Ataman Hati̇poğlu, Ferah Ergi̇n, Günay Tuncer Ertem, Cemal Bulut, Ruki̇ye Berkem, Ali̇ Pekcan Demi̇röz
Reliability Of Self-Reported History In Predicting Immunity Against Measles, Rubella, Mumps, And Varicella Among Health Care Workers, Çi̇gdem Ataman Hati̇poğlu, Ferah Ergi̇n, Günay Tuncer Ertem, Cemal Bulut, Ruki̇ye Berkem, Ali̇ Pekcan Demi̇röz
Turkish Journal of Medical Sciences
To determine the immunity of health care workers (HCWs) against measles, rubella, mumps, and varicella infections, and to evaluate the reliability of self-reported history of the disease in predicting immunity. Materials and methods: A self-reported questionnaire was used to obtain the history of the diseases and ELISA to screen specific IgG antibodies. The history of the diseases was compared with serological testing results. Results: Eighty-one HCWs were included in the study. Immunity against measles was 97.5%, rubella 100%, mumps 72.8%, and varicella 96.3%. Positive predictive values of positive histories of the diseases were 100% for measles and rubella, 96.5% for …
Histomorphometric Study On The Effect Of Low Dose Deltamethrin On The Developing Cerebellar Cortex, Mohd Asnizam Asari, Mohammad Shukri Abdullah, Zul Izhar Mohd Ismail
Histomorphometric Study On The Effect Of Low Dose Deltamethrin On The Developing Cerebellar Cortex, Mohd Asnizam Asari, Mohammad Shukri Abdullah, Zul Izhar Mohd Ismail
Turkish Journal of Medical Sciences
Deltamethrin is a widely used type II pyrethroid-based insecticide. Studies have indicated that neonatal exposure to deltamethrin, even at relatively low doses, results in behavioral and neurological changes. In the present study, the effect of early neonatal exposure to low doses of deltamethrin on the histogenesis of the cerebellar cortex was investigated. Materials and methods: Sprague Dawley male pups were exposed to deltamethrin daily at a dose of 1 mg/kg via intraperitoneal injection from the 2nd to the 5th postnatal day and sacrificed on postnatal days 6, 14, and 21. Following intracardiac perfusion, the cerebellum was removed, embedded with paraffin …
The Effects Of Adjuvant Therapies For Sepsis On Hepatic And Renal Function: A Retrospective Analysis Of 108 Icu Patients, Beri̇t Gökçe Ceylan, Lütfi̇ Yavuz, Füsun Eroğlu, Şenol Gülmen, Ömer Ridvan Tarhan, Adnan Alaca
The Effects Of Adjuvant Therapies For Sepsis On Hepatic And Renal Function: A Retrospective Analysis Of 108 Icu Patients, Beri̇t Gökçe Ceylan, Lütfi̇ Yavuz, Füsun Eroğlu, Şenol Gülmen, Ömer Ridvan Tarhan, Adnan Alaca
Turkish Journal of Medical Sciences
As liver and kidney failure have a direct effect on mortality, morbidity, and intensive care unit (ICU) length of stay in sepsis patients, maintaining their functions or minimizing the degree of failure should be one of the most important goals of therapy. In this retrospective study we investigated the effects of recently introduced adjuvant therapies on hepatorenal functions in septic ICU patients. Materials and methods: We conducted comparative and retrospective data analysis of 108 patients with sepsis that were followed-up during a 2-year period in the ICU. We recorded AST, ALT, ALP, albumin, bilirubin, and INR in order to evaluate …
Levels Of Haemophilus Influenzae Type B (Hib) Antibody In Turkey Before Routine Immunization, Cemi̇le Sönmez, Ni̇lay Çöplü, Demet Kurtoğlu, Berri̇n Esen, Annette Crowley Luke, Lorraine Ransley, Ayşegül Gözalan
Levels Of Haemophilus Influenzae Type B (Hib) Antibody In Turkey Before Routine Immunization, Cemi̇le Sönmez, Ni̇lay Çöplü, Demet Kurtoğlu, Berri̇n Esen, Annette Crowley Luke, Lorraine Ransley, Ayşegül Gözalan
Turkish Journal of Medical Sciences
The Haemophilus influenzae type b (Hib) vaccine was introduced into the routine immunization schedule in Turkey on January 1, 2007. This study investigates the immunity to Hib prior to the introduction of the vaccine. Materials and methods: Serum samples were collected from healthy volunteers between the ages of 6 months and 50 + years of age, living in the area of 26 health centers in the Samsun, Antalya, and Diyarbakir provinces during 2000-2001. In total, 1713 sera were selected for this study, and the younger age groups were given priority (range 0-82). A commercial ELISA test was used to measure …
Prevalence Of Helicobacter Pylori Infection In Healthcare Workers, Maliheh Metanat, Batool Sharifi-Mood, Shahrokh Izadi
Prevalence Of Helicobacter Pylori Infection In Healthcare Workers, Maliheh Metanat, Batool Sharifi-Mood, Shahrokh Izadi
Turkish Journal of Medical Sciences
Helicobacter pylori (H. pylori) is a major factor in inflammatory and malignant diseases of the gastrointestinal tract. The epidemiologic pattern of this infection varies among developed and developing countries, and is related to the general standards of living in each region. In view of the importance of this infection and its different prevalence in different regions of Iran, as well as its long-term complications, this study was conducted to investigate the prevalence of H. pylori infection and its contributing factors in Zahedan. Materials and methods: Ninety-seven healthcare workers without digestive symptoms or a history of H. pylori eradication were randomly …
The Prevalence Of Trichomonas Vaginalis Infection Among Patients That Presented To Hospitals In The Kermanshah District Of Iran In 2006 And 2007, Abdolali Chalechale, Isaac Karimi
The Prevalence Of Trichomonas Vaginalis Infection Among Patients That Presented To Hospitals In The Kermanshah District Of Iran In 2006 And 2007, Abdolali Chalechale, Isaac Karimi
Turkish Journal of Medical Sciences
To determine the prevalence of Trichomonas vaginalis (Tv) among women that presented to hospitals in the Kermanshah district of Iran in 2006 and 2007. Materials and methods: This retrospective study included 33.690 women that presented to primary pathology laboratories in Kermanshah. Vaginal and cervical swabs were collected, and then stained with Papanicolaou (Pap) stain. Additionally, seasonal variations in the prevalence rate were compared to identify significant differences in the prevalence of Tv according to season. Results: Among the 33,690 women, 300 were infected with Tv (a prevalence rate of 0.9%). The 30-39-year-old age group had a significantly higher prevalence of …
Atypical Clinical Manifestation Of Dementia: A Progressive Visuospatial Deficit, Mehmet Güney Şenol, Hakan Tekeli̇, Erdem Toğrol, Mehmet Saraçoğlu
Atypical Clinical Manifestation Of Dementia: A Progressive Visuospatial Deficit, Mehmet Güney Şenol, Hakan Tekeli̇, Erdem Toğrol, Mehmet Saraçoğlu
Turkish Journal of Medical Sciences
Clinically and neuropathologically dementia is a very heterogeneous disease. Alzheimer's disease (Alzheimer disease, AD), the most common cause of dementia, is an acquired cognitive and behavioral impairment of sufficient severity that markedly interferes with social and occupational functioning. This disease may be manifested as progressive memory problems, visuospatial deterioration, aphasia and/or deficits of executive functions. The patient we report here is a 73-year-old female patient with loss of ability of finding directions and understanding the shapes of materials. Her complaints increased progressively during the last two years. Even if she had retired from tailoring, she had deterioration in the visuospatial …
Is Oxidative Stress An Etiologic Factor In Idiopathic Male Infertility?, Ercan Yeni̇, Hali̇l Çi̇ftçi̇, Murat Savaş, Ayhan Veri̇t, Abdullah Taşkin
Is Oxidative Stress An Etiologic Factor In Idiopathic Male Infertility?, Ercan Yeni̇, Hali̇l Çi̇ftçi̇, Murat Savaş, Ayhan Veri̇t, Abdullah Taşkin
Turkish Journal of Medical Sciences
The total antioxidant capacity (TAC) and total peroxide (TP) levels in the blood and seminal plasma of idiopathic infertile patients were compared with those of fertile controls to determine the role of oxidative stress in the etiology of idiopathic male infertility. Material and methods: Thirty-two idiopathic infertile males and 30 healthy, married, age-matched control subjects were included in the study. TAC and TP levels were measured in the blood and seminal plasma, and sperm parameters were studied in both groups. Results: Sperm parameters were significantly impaired in the study group compared with the controls. Blood plasma TAC and TP levels …
The Prognostic Value Of Histological Grade In The Outcome Of Patients With Invasive Breast Cancer, Gül Dağlar, Yunus Nadi̇ Yüksek, Ahmet Uğur Gözalan, Tanju Tütüncü, Yeşi̇m Güngör, Nuri̇ Aydin Kama
The Prognostic Value Of Histological Grade In The Outcome Of Patients With Invasive Breast Cancer, Gül Dağlar, Yunus Nadi̇ Yüksek, Ahmet Uğur Gözalan, Tanju Tütüncü, Yeşi̇m Güngör, Nuri̇ Aydin Kama
Turkish Journal of Medical Sciences
Prognostic factors are useful for the prediction of survival in breast cancer patients. According to many studies, tumor size and lymph node stage are the most powerful predictors of tumor behavior. The aim of the present study was to investigate the prognostic value of tumor histological grade. Materials and methods: The study included 214 operable breast cancer patients treated at the same institution that were evaluated to determine the prognostic value of tumor histological grade. Clinico-histopathological features of the patients were also evaluated for overall survival (OS) and disease-free survival (DFS). Results: Tumor histological grade was an independent factor in …
Can [F-18] Fluorodeoxyglucose Positron Emission Tomography Replace Sentinel Lymph Node Biopsy For The Detection Of Axillary Metastases In Patients With Early-Stage Breast Cancer?*, Semi̇h Görgülü, Mehmet Fati̇h Can, Oğuz Hançerli̇oğullari, Nuri̇ Arslan, Erkan Öztürk, Emel Öztürk, Müjdat Balkan, Turgut Tufan
Can [F-18] Fluorodeoxyglucose Positron Emission Tomography Replace Sentinel Lymph Node Biopsy For The Detection Of Axillary Metastases In Patients With Early-Stage Breast Cancer?*, Semi̇h Görgülü, Mehmet Fati̇h Can, Oğuz Hançerli̇oğullari, Nuri̇ Arslan, Erkan Öztürk, Emel Öztürk, Müjdat Balkan, Turgut Tufan
Turkish Journal of Medical Sciences
To investigate the value of fluorodeoxyglucose positron emission tomography (FDG-PET) in detecting axillary involvement, and to compare its accuracy with sentinel lymph node biopsy (SLNB) in patients with clinically early-stage breast cancer. Materials and methods: Twenty-eight female patients with histologically-confirmed T1-2 breast cancer who were scheduled to have SLNB were included in the study. FDG-PET images were obtained 1-7 days prior to surgery with an intravenous injection of 370 MBq of FDG, while plasma glucose levels were maintained below 120 mg/dL. All the images were interpreted by 2 independent nuclear medicine specialists, who were blinded to the histological diagnoses. SLNB …
Underlying Diseases Of Recurrent Pneumonia In Turkish Children*, Osman Özdemi̇r, Si̇nan Sari, Arzu Bakirtaş, Peli̇n Zorlu, Ülker Ertan
Underlying Diseases Of Recurrent Pneumonia In Turkish Children*, Osman Özdemi̇r, Si̇nan Sari, Arzu Bakirtaş, Peli̇n Zorlu, Ülker Ertan
Turkish Journal of Medical Sciences
The aim of the present study was to determine the relative frequency of recurrent pneumonia in children and to describe its underlying illnesses. Materials and methods: Children between 3 months and 16 years old who had a history of 2 or more episodes of pneumonia per year, or 3 or more episodes in a lifetime were investigated retrospectively at Doctor Sami Ulus Children's Training and Research Hospital between January 2002 and December 2004. Results: Out of 595 children admitted for pneumonia, 62 (10.42%) met the criteria for recurrent pneumonia. An underlying illness was demonstrated in 56 patients (90.32%). In this …