Medicine and Health Sciences Commons^™

The Effects Of Moderate Exercise Training On Nutrient Intake In Mildly Obese Women, Leann Onasch

Loma Linda University Electronic Theses, Dissertations & Projects

The relationship between moderate exercise training (five 45 min sessions/week, brisk walking at 62+2% V0_2max for 15 weeks) and changes in nutrient intake was investigated in a group of 36 sedentary, mildly obese women, conducted using a two (exercise, EX and nonexercise, NEX groups) x three (baseline, six-, 15-week testing sessions) factorial design, with data analyzed using repeated measures ANOVA. The pattern of change over time between groups for kilocalorie intake tended to be different between groups [F(2,68)=2.50,p=0.089] with the EX group experiencing a significant decrease versus baseline by 15 weeks. Significant group x time interactions were found for …

Effects Of Trigger Point Massage And Transcutaneous Electrical Stimulation On Muscular Tension In The Upper Trapezius, Kathryn L. Strum

All-Inclusive List of Electronic Theses and Dissertations

The study investigated the treatment methods of trigger point massage therapy and transcutaneous electrical muscle stimulation (TENS) with the intent of clarifying which method decreased the level of muscular tension in the upper trapezius muscle more effectively over various time periods. The members of the Indiana State University softball team, consisting of sixteen women, were the subjects for this study. The subjects were randomly assigned to one of three groups: a trigger point massage group; a TENS group; and a control group. Using electromyography, the subjects were tested four times throughout the treatment procedure. The control group participated in the …

Effects Of Applied Soil Repellent Finish On Pesticide Residues In Work Clothing, Sandra L. Prior

Community & Environmental Health Theses & Dissertations

This study explores the feasibility of using an applied soil repellent finish, Scotchgard, on 100% cotton denim fabric in order to enhance the removal of atrazine and alachlor residue during the laundering process. The experimental findings provided no statistically significant evidence that Scotchgard fabric protector reduced pesticide residuals on the 100% cotton denim fabric either before or after laundering. A significant finding secondary to the study involved the possible interaction of Scotchgard with the pesticide alachlor, leaving greater amounts of residual on the fabric after laundering than those found with no fabric treatment. This suggests that agricultural workers be cautioned …

Development Of Catalytic Rnas As Potential Anti-Hiv-1 Agents, Pairoj Sae Chang

Loma Linda University Electronic Theses, Dissertations & Projects

RNA molecules with enzymatic activity (ribozymes) targeted to the genome of HIV-1 were developed and demonstrated to mediate site-specific cleavage of the HIV-1 RNA in vitro and to inhibit viral proliferation intracellularly. Two classes of ribozymes that incorporate a "hammerhead" catalytic center were utilized, eotide elements in the viral sequence to provide half of the The first class used nuclcatalytic center. A complementary strand harboring the remaining active site nucleotides was supplied in trans and directed the site-specific cleavage of the HIV-1 RNA target. A second type of ribozyme incorporated the entire catalytic center, minus the site of cleavage, within …

Proto-Oncogene Regulation By Growth Factors In Bone Cells, Harold Lyndon Merriman

Loma Linda University Electronic Theses, Dissertations & Projects

Previous studies have shown that bone cells in culture produce a number of growth factors that are important in bone regulation. Chick and mouse primary calvarial cultures consist of a mixture of cell types that make it difficult to interpret the results from these model systems. In contrast, MC3T3-E1 cells are a clonal mouse osteoblast-like cell line. Since MC3T3-E1 cells consist of a single population of calvarial cells, they make an ideal system in which to study the autocrine effects of bone growth factors.

Based on this work, MC3T3-E1 cells are now known to produce IGF-I, TGF-beta and IGF-II in …

Electrophysiology, Cell Calcium, And Mechanisms Of Hepatocyte Volume Regulation, Walid E. Khalbuss

Electronic Theses and Dissertations

The electrophysiologic technique (Reuss, L., Proc. Natl. Acad. Sci. USA 82:6014, 1985) was modified to measure changes in steady-state hepatocyte volume during osmotic stress. Hepatocytes in mouse liver slices were loaded with tetramethylammonium ion (TMA$\sp{+}$) during transient exposure of cells to nystatin. Intracellular TMA$\sp{+}$ activity (a$\sp{\rm i}\sb{\rm TMA}$) was measured with TMA$\sp{+}$-sensitive, double-barreled microelectrodes. Loading hepatocytes with TMA$\sp{+}$ did not change their membrane potential (V$\sb{\rm m}$), and under steady-state conditions a$\sp{\rm i}\sb{\rm TMA}$ remained constant over 4 min in single impalements. Hyperosmotic solutions (50, 100, & 150 mM sucrose added to media) and hyposmotic solutions (sucrose in media reduced by …

Santa Clara Magazine, Volume 32 Number 4, Summer 1990, Santa Clara University

Santa Clara Magazine

10 - WHAT'S UP WITH COMIC BOOKS? Comic books aren't what they used to be but they continue to charm our children. By Mitch Finley '73

14 - STRESS, ILLNESS, AND PSYCHOTHERAPY The meaning of a stressful situation determines whether it is perceived as a challenge to be overcome or a demoralization. By Jerome D. Frank

18 - A BEELINE TO THE USA "Killer" bees have been winging their way from Brazil since scores of queens escaped a Sao Paolo lab in 1957. By Paul M. McCarthy '46

21 - PROMISE & OPPORTUNITY An economic forecast for the 1990s by …

The Growth Of Simian Virus 40 (Sv40) Host Range/Adenovirus Helper Function Mutants In An African Green Monkey Cell Line That Constitutively Expresses The Sv40 Agnoprotein., Terryl P. Stacy, Michele Chamberlain, Susan Carswell, Charles N. Cole

Dartmouth Scholarship

The simian virus 40 T-antigen carboxy-terminal mutants, dlA2459 and dlA2475, are cell line and temperature dependent for growth and plaque formation in monkey kidney cells. Although these mutants did form plaques on BSC-1 cells at 37 degrees C, they were about fivefold less efficient for plaque formation than wild-type simian virus 40. These mutants did not grow in CV-1 cells and did not synthesize agnoprotein in those cells. CV-1 cells which constitutively express the agnoprotein were permissive for mutant plaque formation. However, late mRNAs, virion proteins, and progeny virion yields did not accumulate to wild-type levels during mutant infection of …

Microwell Based Solid Phase Competitive Enzyme Immunoassay For Estradiol And Estriol, Jeng-Ting Yang

Chemistry & Biochemistry Theses & Dissertations

A sensitive and simple microwell based competition enzyme immunoassay for the quantitative determination of estradiol (E₂) and estriol (E₃) was developed. Nicrowells coated with antibody were incubated with antigen followed by adding horseradish peroxidase (HRPO) conjugate. The assay, which can be performed within two hours at room temperature, involved simultaneous incubation of E₂ - or E₃-HRPO conjugate and serum sample in polystyrene microwells coated with anti- E₂ or anti-E₃ gamma globulin fraction.

Gamma globulin was isolated from whole anti-serum by DEAE-cellulose chromatography. A carbodiimide coupling method was utilized to prepare the …

Development Of A Solid Phase Enzyme Immunoassay For Total Serum Testosterone, Li Li

Chemistry & Biochemistry Theses & Dissertations

An enzyme-labeled immunoassay of sufficient range and sensitivity was developed for serum testosterone determination. In this method, the testosterone in the serum sample and testosterone-HRPO conjugate compete with each other for the limited antibody binding sites on the anti-testosterone gamma globulin coated microwell. The assay can be performed in only 2.5 hours.

The gamma globulin fraction was isolated from the anti-testosterone whole serum by DEAE-cellulose column chromatography. Testosterone-peroxidase conjugate was prepared by a carbodiimide coupling method. The interference which arises from the binding of testosterone to steroid hormone binding protein was eliminated by the addition of 17 beta-estradiol. All assay …

The Determination Of Clomiphene Citrate And Tamoxifen In Human Blood Plasma And Semen, Janice Irene Kiss

Chemistry & Biochemistry Theses & Dissertations

Triphenylethylene antiestrogen compounds are used to stimulate ovulation in anovulary women and spermatogenesis in oligozoospermatic males. Clomiphene Citrate (CC) is given therapeuticaly as a mixture of the trans (E) and cis (Z) isomers. Each of these isomers has its own characteristic agonist-antagonist profiles. Only the trans form of Tamoxifen (T) is administered therapeutically.

HPLC methodologies were developed for the determination of CC and Tin human blood and seminal plasma. The methodologies involved extraction of the triphenylethylene compounds using hexane, followed by evaporation of the hexane under N₂. The residue was then taken up in a volume of HPLC …

Access To Health Care: A U.S. Congressional Staffer's Perspective On A National Problem, Phyllis M. Albritton

Henry Ford Hospital Medical Journal

No abstract provided.

Minority Health And Public Policy: Developing An Agenda Toward The Year 2000, Warren W. Hewitt Jr.

Henry Ford Hospital Medical Journal

No abstract provided.

Primary Care: The Urban Hospital's Role, Bruce C. Vladeck

Henry Ford Hospital Medical Journal

No abstract provided.

Subacute Care In Urban Hospitals: A Case For Urban Swingbeds, Sarah A. Grim

Henry Ford Hospital Medical Journal

No abstract provided.

Senator Kennedy's Proposal To Guarantee Basic Health Benefits For All Americans, David Nexon

Henry Ford Hospital Medical Journal

No abstract provided.

The Role Of Group Health Cooperative In The Development Of Washington State's Basic Health Plan, Aubrey Davis

Henry Ford Hospital Medical Journal

No abstract provided.

The Challenges Of Urban Health Care Delivery, Edward J. Connors

Henry Ford Hospital Medical Journal

No abstract provided.

Fighting The Pushers In Minority America, Caswell A. Evans Jr.

Henry Ford Hospital Medical Journal

No abstract provided.

The Epidemic Of Violence And Its Impact On The Health Care System, Deborah Prothrow-Stith

Henry Ford Hospital Medical Journal

No abstract provided.

Future Directions For Urban Health Care, Symond R. Gottlieb, Gail L. Warden, Iris R. Shannon, Seth L. Foldy, David M. Kinzer

Henry Ford Hospital Medical Journal

No abstract provided.

The Other National Debt, Bruce W. Steinhauer, David C. Leach, Mary West, Sheila Keefe

Henry Ford Hospital Medical Journal

No abstract provided.

The Real-World Issues In Access To Care, David M. Kinzer

Henry Ford Hospital Medical Journal

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The National Health Agenda: The Troubling Future Of The American People, Reed V. Tuckson

Henry Ford Hospital Medical Journal

No abstract provided.

The San Diego County Medical Services Program, Ron Threatt

Henry Ford Hospital Medical Journal

No abstract provided.

The Aids Epidemic: Casting Light Into The Darkness, Evelyn Fisher

Henry Ford Hospital Medical Journal

No abstract provided.

Approaches To Financing Care For The Uninsured, S. E. Berki

Henry Ford Hospital Medical Journal

No abstract provided.

The Basic Health Plan Of The State Of Washington, W. Featherstone Reid

Henry Ford Hospital Medical Journal

No abstract provided.

Implementation Of The Washington State Basic Health Plan, Thomas L. Kobler

Henry Ford Hospital Medical Journal

No abstract provided.